Knowledge

Potassium citrate

Source 📝

241: 151: 24: 521: 747:
Potassium citrate liquid is usually administered by mouth in a diluted aqueous solution, because of its somewhat caustic effect on the stomach lining, and the potential for other mild health hazards. Pill tablets also exist in normal, and extended-release formulations.
88: 979: 665:
Potassium citrate is rapidly absorbed when given by mouth, and is excreted in the urine. Since it is an alkaline salt, it is effective in reducing the pain and frequency of
457: 703: 534: 1344: 1049: 290: 669:
when these are caused by highly acidic urine. It is used for this purpose in dogs and cats, but is chiefly employed as a non-irritating
768: 1898: 872:
Phillips, Rebecca; Hanchanale, Vishwanath S; Myatt, Andy; Somani, Bhaskar; Nabi, Ghulam; Biyani, C Shekhar (6 October 2015).
529: 1086: 950: 1042: 255: 1942: 1915: 541: 935: 786: 1952: 1035: 198: 146: 108: 1957: 860: 219: 725: 1834: 1775: 1626: 1403: 974: 433: 264:
InChI=1S/C6H8O7.3K/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3
1443: 1146: 1141: 274:
InChI=1/C6H8O7.3K/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3
629:
In 2020, it was the 297th most commonly prescribed medication in the United States, with more than 1
1806: 236: 1903: 1111: 1811: 1418: 1370: 1287: 1131: 921: 657:
to it. The solution can then be filtered and the solvent can be evaporated till granulation.
1598: 1563: 1473: 1320: 1269: 646: 1017: 1463: 1325: 1297: 1234: 736: 207: 128: 36: 8: 1375: 1350: 1330: 1315: 1224: 1219: 1204: 1199: 1194: 695:. A systematic review showed a significant reduction in the incidence of stone formation 654: 650: 64: 54: 849: 825: 240: 150: 1789: 1611: 1483: 1335: 1254: 1209: 1126: 1078: 1058: 898: 873: 874:"Citrate salts for preventing and treating calcium containing kidney stones in adults" 1947: 1857: 1852: 1693: 1593: 1588: 1550: 1468: 1380: 1360: 1264: 1259: 1244: 1229: 1214: 1166: 1161: 1136: 1101: 1096: 903: 780: 1752: 1744: 1698: 1675: 1657: 1545: 1438: 1423: 1413: 1365: 1355: 1239: 1121: 1106: 893: 889: 885: 677: 595:
taste. It contains 38.28% potassium by mass. In the monohydrate form, it is highly
564: 468: 403: 313: 1018:"Potassium citrate improves renal function in rats with polycystic kidney disease" 800: 187: 1880: 1862: 1829: 1770: 1721: 1716: 1621: 1516: 1428: 1398: 1292: 1249: 1171: 1151: 1116: 1091: 718: 975:
US Fire extinguishing composition and method for fire extinguishing 5945025A
1909: 1760: 1606: 1568: 1511: 1488: 1478: 1458: 1448: 1433: 1408: 1176: 1156: 729: 512: 728:
that is particularly useful against kitchen fires. Its alkaline pH encourages
496: 1936: 1640: 1493: 1453: 696: 688: 607: 392: 382: 166: 139: 1027: 1739: 1062: 907: 724:
Frequently used in an aqueous solution with other potassium salts, it is a
615: 600: 463: 1580: 1537: 733: 714: 681: 642: 596: 588: 568: 355: 1765: 1555: 1279: 692: 414: 340: 119: 1307: 1186: 666: 619: 561: 511:
Except where otherwise noted, data are given for materials in their
1872: 1821: 1798: 1708: 1521: 707: 670: 611: 420: 158: 87: 23: 1844: 1616: 1529: 623: 610:, potassium citrate is used to regulate acidity, and is known as 425: 372: 174: 1667: 1649: 1503: 1390: 99: 641:
Potassium citrate can be synthesized by the neutralization of
871: 77: 224: 1731: 1685: 706:
in the treatment of mild urinary tract infections, such as
592: 362: 676:
Potassium citrate is an effective way to treat/manage
159: 41:Tripotassium 2-hydroxypropane-1,2,3-tricarboxylate 732:to insulate the fuel from oxidizing air, and the 1934: 186: 973: 951:"What is a Class K Fire Extinguisher Used For?" 63: 1057: 1043: 1022:Journal of the American Society of Nephrology 614:E332. Medicinally, it may be used to control 739:absorbs heat energy to reduce temperatures. 687:It is widely used to treat urinary calculi ( 826:"Potassium Citrate - Drug Usage Statistics" 775:. Archived from the original on 2017-08-15. 1050: 1036: 591:crystalline powder. It is odorless with a 239: 149: 127: 897: 206: 878:Cochrane Database of Systematic Reviews 235: 1935: 763: 761: 691:), and is often used by patients with 397:230 °C (446 °F; 503 K) 387:180 °C (356 °F; 453 K) 140: 1031: 645:which is achieved by the addition of 267:Key: QEEAPRPFLLJWCF-UHFFFAOYSA-K 107: 936:"Soft Drinks with Potassium Citrate" 467: 861:Potassium Citrate for Kidney Stones 758: 277:Key: QEEAPRPFLLJWCF-DFZHHIFOAD 177: 13: 14: 1969: 1010: 742: 998:IOP Conf. Ser.: Mater. Sci. Eng. 955:resources.impactfireservices.com 948: 922:"Potassium citrate for cystitis" 519: 22: 1288:adenosine triphosphate disodium 986: 967: 515:(at 25 °C , 100 kPa). 1024:. Retrieved December 17, 2016. 942: 928: 914: 890:10.1002/14651858.CD010057.pub2 865: 854: 843: 818: 793: 1: 751: 726:wet chemical fire suppressant 1404:Glucose with sodium chloride 636: 571:with the molecular formula K 7: 699:0.26, 95% CI 0.10 to 0.68. 485:or concentration (LD, LC): 345:306.395 g/mol 10: 1974: 1087:β-hydroxy-β-methylbutyrate 850:Medscape on hypocitraturia 298:...O=C()CC(O)(C()=O)CC(=O) 1893: 1871: 1843: 1820: 1797: 1788: 1730: 1707: 1684: 1666: 1648: 1639: 1502: 1389: 1306: 1278: 1185: 1077: 1070: 977:, James A. Cunningham 785:: CS1 maint: unfit URL ( 509: 481: 476: 450: 306: 286: 251: 47: 35: 30: 21: 713:It is also used in many 1943:Food acidity regulators 660: 633:million prescriptions. 702:It is also used as an 505:5400mg/kg (oral, rat) 1564:methylsulfonylmethane 801:"The Top 300 of 2020" 647:potassium bicarbonate 1602:-adenosyl methionine 1298:monosodium phosphate 737:dehydration reaction 680:, if the patient is 558:tripotassium citrate 37:Preferred IUPAC name 1953:Potassium compounds 1835:monofluorophosphate 1345:+hydrogen carbonate 1059:Mineral supplements 769:"Potassium Citrate" 655:potassium hydroxide 651:potassium carbonate 503:170 mg/kg (IV, dog) 404:Solubility in water 167:(antioxidants, ...) 18: 1958:E-number additives 1920:Never to phase III 1612:Sodium thiosulfate 1444:hydrogen carbonate 542:Infobox references 17:Potassium citrate 16: 1930: 1929: 1889: 1888: 1784: 1783: 1755: 1747: 1635: 1634: 1594:protamine sulfate 1589:potassium sulfate 1575: 1558: 1540: 1532: 1524: 1147:lactate gluconate 1142:glycerylphosphate 587:. It is a white, 554:Potassium citrate 550:Chemical compound 548: 547: 220:CompTox Dashboard 89:Interactive image 1965: 1807:(III) picolinate 1795: 1794: 1753: 1745: 1676:potassium iodide 1646: 1645: 1573: 1556: 1546:Iron(II) sulfate 1538: 1530: 1522: 1112:+cholecalciferol 1075: 1074: 1052: 1045: 1038: 1029: 1028: 1004: 990: 984: 983: 982: 978: 971: 965: 964: 962: 961: 946: 940: 939: 932: 926: 925: 918: 912: 911: 901: 884:(10): CD010057. 869: 863: 858: 852: 847: 841: 840: 838: 836: 822: 816: 815: 813: 811: 797: 791: 790: 784: 776: 765: 704:alkalizing agent 632: 532: 526: 523: 522: 471: 314:Chemical formula 244: 243: 228: 226: 210: 190: 179: 161: 153: 142: 131: 111: 91: 67: 26: 19: 15: 1973: 1972: 1968: 1967: 1966: 1964: 1963: 1962: 1933: 1932: 1931: 1926: 1925: 1910:Clinical trials 1885: 1867: 1839: 1816: 1780: 1726: 1703: 1680: 1662: 1631: 1517:Calcium sulfate 1498: 1419:calcium edetate 1399:Docusate sodium 1385: 1302: 1274: 1181: 1066: 1056: 1013: 1008: 1007: 992:Xiaofang Wangy 991: 987: 980: 972: 968: 959: 957: 947: 943: 934: 933: 929: 924:. patient.info. 920: 919: 915: 870: 866: 859: 855: 848: 844: 834: 832: 824: 823: 819: 809: 807: 799: 798: 794: 778: 777: 767: 766: 759: 754: 745: 719:buffering agent 663: 639: 630: 586: 582: 578: 574: 556:(also known as 551: 544: 539: 538: 537:  ?) 528: 524: 520: 516: 504: 500: 494: 460: 442: 423: 406: 354: 334: 330: 326: 322: 316: 302: 299: 294: 293: 282: 279: 278: 275: 269: 268: 265: 259: 258: 247: 229: 222: 213: 193: 180: 134: 114: 94: 81: 70: 57: 43: 42: 12: 11: 5: 1971: 1961: 1960: 1955: 1950: 1945: 1928: 1927: 1924: 1923: 1922: 1921: 1918: 1907: 1901: 1895: 1894: 1891: 1890: 1887: 1886: 1884: 1883: 1877: 1875: 1869: 1868: 1866: 1865: 1860: 1855: 1849: 1847: 1841: 1840: 1838: 1837: 1832: 1826: 1824: 1818: 1817: 1815: 1814: 1812:(III) chloride 1809: 1803: 1801: 1792: 1786: 1785: 1782: 1781: 1779: 1778: 1773: 1768: 1763: 1758: 1750: 1742: 1736: 1734: 1728: 1727: 1725: 1724: 1719: 1713: 1711: 1705: 1704: 1702: 1701: 1696: 1690: 1688: 1682: 1681: 1679: 1678: 1672: 1670: 1664: 1663: 1661: 1660: 1654: 1652: 1643: 1637: 1636: 1633: 1632: 1630: 1629: 1624: 1619: 1614: 1609: 1607:Sodium sulfate 1604: 1596: 1591: 1586: 1584:-α-lipoic acid 1578: 1566: 1561: 1553: 1548: 1543: 1535: 1527: 1519: 1514: 1512:barium sulfate 1508: 1506: 1500: 1499: 1497: 1496: 1491: 1489:Suramin sodium 1486: 1481: 1476: 1474:stibogluconate 1471: 1466: 1461: 1456: 1451: 1446: 1441: 1436: 1431: 1426: 1421: 1416: 1411: 1409:Heparin sodium 1406: 1401: 1395: 1393: 1387: 1386: 1384: 1383: 1378: 1373: 1368: 1363: 1358: 1353: 1348: 1338: 1333: 1328: 1323: 1318: 1312: 1310: 1304: 1303: 1301: 1300: 1295: 1293:hydroxyapatite 1290: 1284: 1282: 1276: 1275: 1273: 1272: 1267: 1262: 1257: 1252: 1247: 1242: 1237: 1232: 1227: 1222: 1217: 1212: 1207: 1202: 1197: 1191: 1189: 1183: 1182: 1180: 1179: 1177:hydroxyapatite 1174: 1169: 1164: 1159: 1154: 1149: 1144: 1139: 1134: 1132:glucoheptonate 1129: 1124: 1119: 1114: 1109: 1104: 1099: 1094: 1089: 1083: 1081: 1072: 1068: 1067: 1055: 1054: 1047: 1040: 1032: 1026: 1025: 1012: 1011:External links 1009: 1006: 1005: 985: 966: 949:Fire, Impact. 941: 927: 913: 864: 853: 842: 817: 792: 756: 755: 753: 750: 744: 743:Administration 741: 730:saponification 662: 659: 638: 635: 584: 580: 576: 572: 549: 546: 545: 540: 518: 517: 513:standard state 510: 507: 506: 501: 492: 490: 487: 486: 479: 478: 474: 473: 461: 456: 453: 452: 448: 447: 444: 440: 430: 429: 417: 411: 410: 407: 402: 399: 398: 395: 389: 388: 385: 379: 378: 375: 369: 368: 365: 359: 358: 351: 347: 346: 343: 337: 336: 332: 328: 324: 320: 317: 312: 309: 308: 304: 303: 301: 300: 297: 289: 288: 287: 284: 283: 281: 280: 276: 273: 272: 270: 266: 263: 262: 254: 253: 252: 249: 248: 246: 245: 232: 230: 218: 215: 214: 212: 211: 203: 201: 195: 194: 192: 191: 183: 181: 173: 170: 169: 163: 155: 154: 144: 136: 135: 133: 132: 124: 122: 116: 115: 113: 112: 104: 102: 96: 95: 93: 92: 84: 82: 75: 72: 71: 69: 68: 60: 58: 53: 50: 49: 45: 44: 40: 39: 33: 32: 28: 27: 9: 6: 4: 3: 2: 1970: 1959: 1956: 1954: 1951: 1949: 1946: 1944: 1941: 1940: 1938: 1919: 1917: 1914: 1913: 1911: 1908: 1905: 1902: 1900: 1897: 1896: 1892: 1882: 1879: 1878: 1876: 1874: 1870: 1864: 1861: 1859: 1856: 1854: 1851: 1850: 1848: 1846: 1842: 1836: 1833: 1831: 1828: 1827: 1825: 1823: 1819: 1813: 1810: 1808: 1805: 1804: 1802: 1800: 1796: 1793: 1791: 1787: 1777: 1774: 1772: 1769: 1767: 1764: 1762: 1759: 1757: 1751: 1749: 1743: 1741: 1738: 1737: 1735: 1733: 1729: 1723: 1720: 1718: 1715: 1714: 1712: 1710: 1706: 1700: 1697: 1695: 1694:(II) fumarate 1692: 1691: 1689: 1687: 1683: 1677: 1674: 1673: 1671: 1669: 1665: 1659: 1656: 1655: 1653: 1651: 1647: 1644: 1642: 1638: 1628: 1625: 1623: 1620: 1618: 1615: 1613: 1610: 1608: 1605: 1603: 1601: 1597: 1595: 1592: 1590: 1587: 1585: 1583: 1579: 1577: 1571: 1567: 1565: 1562: 1560: 1554: 1552: 1549: 1547: 1544: 1542: 1536: 1534: 1528: 1526: 1520: 1518: 1515: 1513: 1510: 1509: 1507: 1505: 1501: 1495: 1494:Valproic acid 1492: 1490: 1487: 1485: 1482: 1480: 1477: 1475: 1472: 1470: 1467: 1465: 1464:nitroprusside 1462: 1460: 1457: 1455: 1452: 1450: 1447: 1445: 1442: 1440: 1437: 1435: 1432: 1430: 1427: 1425: 1422: 1420: 1417: 1415: 1412: 1410: 1407: 1405: 1402: 1400: 1397: 1396: 1394: 1392: 1388: 1382: 1379: 1377: 1374: 1372: 1369: 1367: 1364: 1362: 1359: 1357: 1354: 1352: 1349: 1346: 1342: 1339: 1337: 1334: 1332: 1329: 1327: 1324: 1322: 1319: 1317: 1314: 1313: 1311: 1309: 1305: 1299: 1296: 1294: 1291: 1289: 1286: 1285: 1283: 1281: 1277: 1271: 1268: 1266: 1263: 1261: 1258: 1256: 1253: 1251: 1248: 1246: 1243: 1241: 1238: 1236: 1233: 1231: 1228: 1226: 1223: 1221: 1218: 1216: 1213: 1211: 1208: 1206: 1203: 1201: 1198: 1196: 1193: 1192: 1190: 1188: 1184: 1178: 1175: 1173: 1170: 1168: 1165: 1163: 1160: 1158: 1155: 1153: 1150: 1148: 1145: 1143: 1140: 1138: 1135: 1133: 1130: 1128: 1125: 1123: 1120: 1118: 1115: 1113: 1110: 1108: 1105: 1103: 1100: 1098: 1095: 1093: 1090: 1088: 1085: 1084: 1082: 1080: 1076: 1073: 1069: 1064: 1060: 1053: 1048: 1046: 1041: 1039: 1034: 1033: 1030: 1023: 1019: 1016:Tanner, G.A. 1015: 1014: 1002: 999: 995: 989: 976: 970: 956: 952: 945: 937: 931: 923: 917: 909: 905: 900: 895: 891: 887: 883: 879: 875: 868: 862: 857: 851: 846: 831: 827: 821: 806: 802: 796: 788: 782: 774: 770: 764: 762: 757: 749: 740: 738: 735: 731: 727: 722: 720: 716: 711: 709: 705: 700: 698: 694: 690: 689:kidney stones 685: 683: 679: 674: 672: 668: 658: 656: 652: 648: 644: 634: 627: 625: 621: 618:derived from 617: 616:kidney stones 613: 609: 608:food additive 604: 602: 598: 594: 590: 570: 566: 563: 559: 555: 543: 536: 531: 514: 508: 502: 498: 489: 488: 484: 480: 475: 470: 465: 462: 459: 455: 454: 451:Pharmacology 449: 445: 439: 435: 432: 431: 427: 424:insoluble in 422: 418: 416: 413: 412: 408: 405: 401: 400: 396: 394: 393:Boiling point 391: 390: 386: 384: 383:Melting point 381: 380: 376: 374: 371: 370: 366: 364: 361: 360: 357: 353:white powder 352: 349: 348: 344: 342: 339: 338: 318: 315: 311: 310: 305: 296: 295: 292: 285: 271: 261: 260: 257: 250: 242: 238: 237:DTXSID8027325 234: 233: 231: 221: 217: 216: 209: 205: 204: 202: 200: 197: 196: 189: 185: 184: 182: 176: 172: 171: 168: 164: 162: 157: 156: 152: 148: 145: 143: 141:ECHA InfoCard 138: 137: 130: 126: 125: 123: 121: 118: 117: 110: 109:ChEMBL1200458 106: 105: 103: 101: 98: 97: 90: 86: 85: 83: 79: 74: 73: 66: 62: 61: 59: 56: 52: 51: 46: 38: 34: 29: 25: 20: 1881:(IV) sulfate 1776:zinc sulfate 1699:(II) sulfate 1627:zinc sulfate 1622:(IV) sulfate 1599: 1581: 1569: 1541:-glutathione 1371:permanganate 1340: 1021: 1000: 997: 993: 988: 969: 958:. Retrieved 954: 944: 930: 916: 881: 877: 867: 856: 845: 833:. Retrieved 829: 820: 808:. Retrieved 804: 795: 772: 746: 723: 712: 701: 686: 675: 664: 640: 628: 605: 601:deliquescent 557: 553: 552: 482: 437: 48:Identifiers 1906:from market 1559:-methionine 1484:thiosulfate 1321:bicarbonate 1270:L-threonate 734:endothermic 715:soft drinks 682:hypokalemic 643:citric acid 597:hygroscopic 589:hygroscopic 569:citric acid 497:median dose 483:Lethal dose 419:soluble in 356:hygroscopic 350:Appearance 307:Properties 147:100.011.596 1937:Categories 1790:Ultratrace 1771:proteinate 1756:-carnosine 1748:-aspartate 1469:phosphates 1326:bitartrate 1280:Phosphorus 1235:levulinate 1127:glubionate 960:2022-08-18 773:hazard.com 752:References 693:cystinuria 678:arrhythmia 415:Solubility 377:1.98 g/cm 341:Molar mass 208:86R1NVR0HW 120:ChemSpider 76:3D model ( 55:CAS Number 1916:Phase III 1904:Withdrawn 1858:carbonate 1853:aspartate 1761:gluconate 1658:gluconate 1576:-cysteine 1525:-cysteine 1439:gluconate 1424:carbonate 1414:ascorbate 1376:phosphate 1351:gluconate 1331:carbonate 1316:ascorbate 1308:Potassium 1225:glycinate 1220:gluconate 1205:carbonate 1200:aspartate 1195:ascorbate 1187:Magnesium 1167:phosphate 1162:pangamate 1137:gluconate 1102:carbonate 1097:ascorbate 835:7 October 810:7 October 667:urination 637:Synthesis 620:uric acid 562:potassium 367:odorless 165:E332(ii) 1948:Citrates 1873:Vanadium 1830:fluoride 1822:Fluorine 1799:Chromium 1722:selenite 1717:selenate 1709:Selenium 1572:-acetyl- 1533:-cystine 1429:chloride 1336:chloride 1255:pidolate 1210:chloride 1122:folinate 1107:chloride 908:26439475 830:ClinCalc 805:ClinCalc 781:cite web 708:cystitis 671:diuretic 612:E number 477:Hazards 472:) 458:ATC code 421:glycerin 409:soluble 160:E number 65:866-84-2 1863:orotate 1845:Lithium 1740:acetate 1617:taurine 1551:sulfate 1479:sulfate 1459:nitrite 1449:lactate 1434:citrate 1381:sulfate 1361:lactate 1341:citrate 1265:taurate 1260:sulfate 1245:orotate 1230:lactate 1215:citrate 1172:sulfate 1152:lactate 1117:citrate 1092:acetate 1079:Calcium 899:9578669 624:cystine 560:) is a 535:what is 533: ( 466: ( 464:A12BA02 434:Acidity 426:ethanol 373:Density 335: 175:PubChem 1899:WHO-EM 1668:Iodine 1650:Copper 1504:Sulfur 1454:malate 1391:Sodium 1366:malate 1356:iodide 1240:malate 1157:malate 1003:022047 981:  906:  896:  631:  593:saline 530:verify 527:  428:(95%) 291:SMILES 100:ChEMBL 31:Names 1766:oxide 1641:Trace 1250:oxide 1071:Major 996:2019 994:et al 717:as a 606:As a 256:InChI 188:13344 129:12775 78:JSmol 1732:Zinc 1686:Iron 904:PMID 882:2015 837:2022 812:2022 787:link 661:Uses 599:and 565:salt 446:8.5 363:Odor 199:UNII 1063:A12 1001:490 894:PMC 886:doi 653:or 622:or 567:of 469:WHO 225:EPA 178:CID 1939:: 1912:: 1020:. 953:. 902:. 892:. 880:. 876:. 828:. 803:. 783:}} 779:{{ 771:. 760:^ 721:. 710:. 697:RR 684:. 673:. 649:, 626:. 603:. 493:50 491:LD 443:) 436:(p 1754:L 1746:L 1600:S 1582:R 1574:L 1570:N 1557:L 1539:L 1531:L 1523:L 1347:) 1343:( 1065:) 1061:( 1051:e 1044:t 1037:v 963:. 938:. 910:. 888:: 839:. 814:. 789:) 585:7 583:O 581:5 579:H 577:6 575:C 573:3 525:N 499:) 495:( 441:a 438:K 333:7 331:O 329:5 327:H 325:6 323:C 321:3 319:K 227:) 223:( 80:)

Index


Preferred IUPAC name
CAS Number
866-84-2
JSmol
Interactive image
ChEMBL
ChEMBL1200458
ChemSpider
12775
ECHA InfoCard
100.011.596
Edit this at Wikidata
E number
(antioxidants, ...)
PubChem
13344
UNII
86R1NVR0HW
CompTox Dashboard
DTXSID8027325
Edit this at Wikidata
InChI
SMILES
Chemical formula
Molar mass
hygroscopic
Odor
Density
Melting point

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.