693:
670:
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49:
58:
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1548:. Tetracycline displayed higher potency, better solubility, and more favorable pharmacology than the other antibiotics in its class, leading to its FDA approval in 1954. The new compound was one of the first commercially successful semi-synthetic antibiotics that was used, and laid the foundation for the development of Sancycline,
1703:
to require tetracycline to develop beyond the larval stage. Modified males raised in a laboratory develop normally as they are supplied with this chemical and can be released into the wild. Their subsequent offspring inherit this trait, but find no tetracycline in their environments, so never develop
1669:
models in mice. Engineers were able to develop a retrovirus that induced a particular type of leukemia in mice, and could then "switch" the cancer on and off through tetracycline administration. This could be used to grow the cancer in mice and then halt it at a particular stage to allow for further
1478:
peptide chain. Tetracycline blocks the A-site so that a hydrogen bond is not formed between the amino acids. Tetracycline binds to the 30S and 50S subunit of microbial ribosomes. Thus, it prevents the formation of a peptide chain. The action is usually not inhibitory and irreversible even with the
1067:
caused by bacterial infections. The mechanism of action for the antibacterial effect of tetracyclines relies on disrupting protein translation in bacteria, thereby damaging the ability of microbes to grow and repair; however, protein translation is also disrupted in eukaryotic
762:
1479:
withdrawal of the drug. Mammalian cells are not vulnerable to the effect of
Tetracycline as these cells contain no 30S ribosomal subunits so do not accumulate the drug. This accounts for the relatively small off-site effect of tetracycline on human cells.
2850:
Litch JM, Encarnacion M, Chen S, Leonard J, Burkoth TL (November 1996). "Use of the polymeric matrix as internal standard for quantitation of in vivo delivery of tetracycline HCl from
Actisite tetracycline fiber during periodontal treatment".
2828:
1605:
described the "big price hikes of some generic drugs" as a "relatively new phenomenon" which has left most pharmacists "grappling" with large upswings" in the "costs of generics, with 'overnight' price changes sometimes exceeding 1,000%."
1314:
Discolor permanent teeth (yellow-gray-brown), from prenatal period through childhood and adulthood. Children receiving long- or short-term therapy with a tetracycline or glycylcycline may develop permanent brown discoloration of the
1169:
in humans. Tetracycline labeling is used to determine the amount of bone growth within a certain period of time, usually a period around 21 days. Tetracycline is incorporated into mineralizing bone and can be detected by its
1174:. In "double tetracycline labeling", a second dose is given 11–14 days after the first dose, and the amount of bone formed during that interval can be calculated by measuring the distance between the two fluorescent labels.
2916:
Dugray A, Geay JF, Foudi A, Bonnet ML, Vainchenker W, Wendling F, et al. (October 2001). "Rapid generation of a tetracycline-inducible BCR-ABL defective retrovirus using a single autoregulatory retroviral cassette".
3296:
980:, and several other previously sensitive organisms is now quite common. Tetracyclines remain especially useful in the management of infections by certain obligately intracellular bacterial pathogens such as
2820:
804:
InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1
3289:
2344:
4087:
3282:
1644:. In the game, players may find the antibiotic to treat the common cold, influenza, cholera and infected wounds, but does not portray any side effects associated with tetracycline.
5158:
1532:(Aureomycin), in 1945. The structure of Aureomycin was elucidated in 1952 and published in 1954 by the Pfizer-Woodward group. After the discovery of the structure, researchers at
6103:
1499:
or a ribosomal protection protein. Efflux pumps actively eject tetracycline from the cell, preventing the build up of an inhibitory concentration of tetracycline in the
1621:. The term "tetracycline" is also used to denote the four-ring system of this compound; "tetracyclines" are related substances that contain the same four-ring system.
897:
5379:
5369:
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923:
Tetracyclines have a broad spectrum of antibiotic action. Originally, they possessed some level of bacteriostatic activity against almost all medically relevant
5384:
6234:
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2886:
1614:
It is marketed under the brand names
Sumycin, Tetracyn, and Panmycin, among others. Actisite is a thread-like fiber formulation used in dental applications.
247:
5151:
2381:
5364:
2754:
Bassett EJ, Keith MS, Armelagos GJ, Martin DL, Villanueva AR (September 1980). "Tetracycline-labeled human bone from ancient
Sudanese Nubia (A.D. 350)".
1022:, are also susceptible to tetracyclines. Tetracycline tablets were used in the plague outbreak in India in 1994. Tetracycline is first-line therapy for
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1662:
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1215:
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2354:
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5234:
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2040:
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mummies from between 350 and 550 A.D. were found to exhibit patterns of fluorescence identical with that of modern tetracycline labelled bone.
1503:. Ribosomal protection proteins interact with the ribosome and dislodge tetracycline from the ribosome, allowing for translation to continue.
5404:
5209:
1752:
145:
6053:
2190:
Sánchez AR, Rogers RS, Sheridan PJ (October 2004). "Tetracycline and other tetracycline-derivative staining of the teeth and oral cavity".
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1893:
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5419:
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2437:
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4065:
440:(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
2168:
3987:
1787:
4939:
4883:
4031:
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1276:
2961:
1248:
2110:
1932:
Lippincott's
Illustrated Reviews: Pharmacology, 4th ed. Harvery RA, Champe, PC. Lippincott, Williams & Wilkins, 2009
1629:
Due to the drug's association with fighting infections, it serves as the main "commodity" in the science fiction series
821:
196:
3648:
2797:
Armelagos G (2000). "Take Two Beers and Call Me in 1,600 Years: Use of
Tetracycline by Nubians and Ancient Egyptians".
2087:
6229:
2461:"Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance"
1887:
952:, which display intrinsic resistance. However, acquired (as opposed to inherent) resistance has proliferated in many
796:
1255:
1234:
5178:
4900:
4048:
2894:
1080:
5953:
1944:"Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research"
6194:
3274:
432:
357:
177:
2377:
2111:"Bait ingestion by free-ranging raccoons and nontarget species in an oral rabies vaccine field trial in Florida"
1564:
Tetracycline has a high affinity for calcium and is incorporated into bones during the active mineralization of
5635:
1578:
It is conjectured that the beer brewed by the
Nubians was the source of the tetracycline found in these bones.
1262:
4002:
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2349:
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610:
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4932:
4832:
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2627:
Stephens CR, Conover LH, Pasternack R, Hochstein FA, Moreland WT, Regna PP, et al. (July 1954).
1907:
1223:
5938:
5485:
5324:
2051:
1993:"Tetracycline antibiotics impair mitochondrial function and its experimental use confounds research"
6204:
6063:
5978:
4351:
3809:
3109:
1618:
1571:
There is evidence that early inhabitants of
Northeastern Africa consumed tetracycline antibiotics.
1488:
1307:
665:
31:
4095:
956:
and greatly eroded the formerly vast versatility of this group of antibiotics. Resistance amongst
4975:
4888:
4036:
3094:
1219:
233:
127:
17:
1544:
reaction replaced a chlorine moiety with a hydrogen, creating a compound named tetracycline via
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5083:
4234:
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2562:
1057:
941:
936:
932:
631:
1877:
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It is also used to produce several semisynthetic derivatives, which together are known as the
896:
Tetracycline was patented in 1953 and was approved for prescription use in 1954. It is on the
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3997:
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3089:
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2707:"Characterization of eight different tetracyclines: advances in fluorescence bone labeling"
1834:
1700:
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in 1948 as natural products, and first prescribed in 1948. Benjamin Duggar, working under
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57:
8:
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5136:
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2429:
2271:, Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases, 2012,
1942:
Moullan N, Mouchiroud L, Wang X, Ryu D, Williams EG, Mottis A, et al. (March 2015).
1658:
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1537:
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1433:
Caution should be exercised in long-term use when breastfeeding. Short-term use is safe;
1375:
946:
449:
240:
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1838:
1568:. When incorporated into bones, tetracycline can be identified using ultraviolet light.
1536:
began chemically modifying aureomycin by treating it with hydrogen in the presence of a
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458:
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2017:
1992:
1968:
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207:
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2207:
2203:
2160:
2130:
2022:
1973:
1883:
1850:
1846:
1742:
1641:
1633:, with the search for tetracycline becoming a major preoccupation in later episodes.
1529:
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982:
621:
490:
169:
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2946:
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Since tetracycline is absorbed into bone, it is used as a marker of bone growth for
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Pautke C, Vogt S, Kreutzer K, Haczek C, Wexel G, Kolk A, et al. (July 2010).
2008:
30:
This article is about the specific antibiotic. For the family of antibiotics, see
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1991:
Chatzispyrou IA, Held NM, Mouchiroud L, Auwerx J, Houtkooper RH (November 2015).
1959:
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Conover LH, Moreland WT, English AR, Stephens CR, Pilgrim FJ (September 1953).
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2231:
2126:
1809:
1565:
1545:
1471:
957:
2597:
2510:"Ribosomal protection proteins and their mechanism of tetracycline resistance"
1470:
Tetracycline inhibits protein synthesis by blocking the attachment of charged
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2318:. John Wiley & Sons, Inc. p. 367 – via ProQuest Ebook Central.
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It is also one of a group of antibiotics which together may be used to treat
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1977:
1912:
World Health
Organization model list of essential medicines: 21st list 2019
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893:
may harm the baby. It works by inhibiting protein synthesis in bacteria.
855:
163:
2683:
2644:
2269:
LiverTox: Clinical and
Research Information on Drug-Induced Liver Injury
1919:
1825:
Nelson ML, Levy SB (December 2011). "The history of the tetracyclines".
1353:
remedies (some common antacids and over-the-counter heartburn medicines)
510:
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5923:
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3263:
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3129:
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2403:
1696:
1457:
use have been reported, but a causative role has not been established.
1233:
if you can. Unsourced or poorly sourced material may be challenged and
1138:
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994:
988:
843:
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3532:
3458:
3433:
3429:
3239:
3159:
3072:
3042:
1598:
1516:
The tetracyclines, a large family of antibiotics, were discovered by
1500:
1421:
1379:
1338:
1161:
Tetracycline hydrochloride is available as yellow crystalline powder.
1122:
890:
476:
414:
149:
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susceptibility data for some medically significant microorganisms:
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501:
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2316:
Antibiotics Manual : A Guide to Commonly Used Antimicrobials
1747:
1182:
1146:
1134:
1039:
1011:
886:
863:
851:
1990:
1597:, in the USA the price of tetracycline rose from $ 0.06 per 250-
4818:
3592:
3031:
2584:
Jukes TH (1985). "Some historical notes on chlortetracycline".
1533:
1327:
1130:
904:. Tetracycline was originally made from bacteria of the genus
601:
2665:
2508:
Connell SR, Tracz DM, Nierhaus KH, Taylor DE (December 2003).
2430:"Antimicrobial Agents in the Treatment of Infectious Disease."
2048:
Susceptibility and Minimum Inhibitory Concentration (MIC) Data
881:
development if used by children less than eight years of age,
877:, rash, and loss of appetite. Other side effects include poor
784:
C1(c2cccc(c2C(=O)C3=C(4((C31)(C(=C(C4=O)C(=O)N)O)N(C)C)O)O)O)O
111:
1417:
1368:
878:
752:
581:
4947:
1125:
parasites, including those responsible for diseases such as
654:
2849:
2753:
1591:
According to data from EvaluatePharma and published in the
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1357:
1346:
1342:
1323:
561:
102:
93:
84:
5166:
2507:
4478:
4129:
1906:
1487:
Bacteria usually acquire resistance to tetracycline from
1364:
1319:
5179:
2704:
1941:
1922:. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
1665:. It has been used as an engineered "control switch" in
2297:"Tinnitus: Ringing in the ears and what to do about it"
1406:
by displacing it from the various protein-binding sites
898:
World Health Organization's List of Essential Medicines
2814:
2812:
6157:
3017:
2915:
2821:"As competition wanes, prices for generics skyrocket"
2189:
1786:. The American Society of Health-System Pharmacists.
1121:
The tetracyclines also have activity against certain
114:
105:
99:
78:
2962:"Can GM mosquitoes rid the world of a major killer?"
1699:, and several other diseases) uses a strain that is
108:
90:
87:
81:
2809:
2108:
1673:A technique being developed for the control of the
96:
2559:"Chemistry and chemical biology of tetracyclines"
2313:
2109:Olson CA, Mitchell KD, Werner PA (October 2000).
842:family of medications, used to treat a number of
6181:
2301:Harvard Health Publishing Harvard Medical School
1528:, discovered the first tetracycline antibiotic,
1429:may result from ingesting expired tetracyclines.
489:
2238:. Treasure Island (FL): StatPearls Publishing.
1875:
1010:. Certain rare or exotic infections, including
464:
457:
27:Antibiotic used to treat a number of infections
3663:
2328:
2229:
1229:Please review the contents of the section and
6235:World Health Organization essential medicines
5152:
4933:
4081:
3649:
3290:
3003:
2471:(2): 232–60, second page, table of contents.
2458:
2333:. Jones & Bartlett Learning. p. 179.
1753:National Center for Biotechnology Information
1437:in milk is low to nil. According to the U.S.
834:, sold under various brand names, is an oral
2329:Riordan J, Wambach K, eds. (November 2010).
2161:"Tetracycline: MedlinePlus Drug Information"
1984:
1177:Tetracycline is also used as a biomarker in
409:8–11 hours, 57–108 hours (kidney impairment)
195:
5435:
1935:
1601:pill in 2013 to $ 4.06 a pill in 2015. The
1482:
365:In general: ℞ (Prescription only)
339:
329:
319:
5486:Allopregnanedione (5α-dihydroprogesterone)
5159:
5145:
4940:
4926:
4549:
4088:
4074:
3656:
3642:
3297:
3283:
3010:
2996:
2465:Microbiology and Molecular Biology Reviews
2050:. TOKU-E. 8 September 2015. Archived from
1827:Annals of the New York Academy of Sciences
1824:
1778:
1776:
1774:
1772:
1770:
1768:
1766:
1764:
1762:
1409:Cause breathing complications, as well as
1349:ions, not to be taken at the same time as
691:
668:
529:
56:
47:
2818:
2796:
2730:
2533:
2484:
2016:
1967:
1820:
1818:
549:
5184:Tooltip Constitutive androstane receptor
2959:
2672:Journal of the American Chemical Society
2633:Journal of the American Chemical Society
2337:
1559:
1156:
2434:Todars Online Text Book of Bacteriology
1759:
918:
664:
509:
168:
14:
6182:
5939:Pregnanedione (5β-dihydroprogesterone)
5325:Pregnanedione (5β-dihydroprogesterone)
3988:Clindamycin/adapalene/benzoyl peroxide
2378:"Mechanism of Action of Tetracyclines"
2092:The Johns Hopkins Medical Institutions
2061:
1900:
1896:from the original on 20 December 2016.
1882:. John Wiley & Sons. p. 489.
1815:
1652:
1581:
1465:
1181:to detect consumption of medicine- or
873:Common side effects include vomiting,
682:
5140:
4921:
4069:
3637:
3278:
2991:
2831:from the original on 19 November 2015
2583:
2514:Antimicrobial Agents and Chemotherapy
2427:
2375:
2345:"FDA Adverse Events Reporting System"
2225:
2223:
2221:
1914:. Geneva: World Health Organization.
1790:from the original on 28 December 2016
1152:
1116:
630:
609:
589:
186:
154:
2972:from the original on 5 December 2013
2192:International Journal of Dermatology
1636:Tetracycline is also represented in
1198:
636:
309:
299:
289:
279:
269:
259:
2440:from the original on 8 October 2013
569:
480:
24:
2865:10.1111/j.1600-0765.1996.tb00518.x
2218:
2067:
1109:
25:
6246:
2556:
2459:Chopra I, Roberts M (June 2001).
2331:Breastfeeding and Human Lactation
2314:Schlossberg DL, Samuel R (2017).
1098:
1094:
939:, with a few exceptions, such as
900:. Tetracycline is available as a
218:
6167:
2819:McCluskey PD (6 November 2015).
2723:10.1111/j.1469-7580.2010.01237.x
2526:10.1128/AAC.47.12.3675-3681.2003
2384:from the original on 5 June 2012
2353:. 27 August 2010. Archived from
2204:10.1111/j.1365-4632.2004.02108.x
2171:from the original on 10 May 2017
2094:. 8 January 2001. Archived from
1847:10.1111/j.1749-6632.2011.06354.x
1295:
1203:
722:
716:
74:
4948:Drugs used for diseases of the
2953:
2909:
2879:
2853:Journal of Periodontal Research
2843:
2790:
2747:
2698:
2659:
2629:"The Structure of Aureomycin 1"
2620:
2577:
2550:
2501:
2452:
2421:
2396:
2369:
2322:
2307:
2289:
2257:
2183:
2153:
2102:
2080:
2070:"Tetracycline labeling of bone"
2033:
1876:Fischer J, Ganellin CR (2006).
1722:"Antibiotic abbreviations list"
1460:
1188:
913:
809:Key:OFVLGDICTFRJMM-WESIUVDSSA-N
5491:Allopregnanolone (brexanolone)
4589:transpeptidation/translocation
2668:"Terramycin. Xi. Tetracycline"
2586:Reviews of Infectious Diseases
2477:10.1128/MMBR.65.2.232-260.2001
2230:Shutter MC, Akhondi H (2024).
1926:
1869:
1802:
1735:
1714:
1609:
1420:, so should be avoided during
1322:, so are not to be taken with
1231:add the appropriate references
728:
710:
13:
1:
6146:Receptor/signaling modulators
6104:Tropanyl 3,5-dimethulbenzoate
5954:Pregnenolone 16α-carbonitrile
4003:Erythromycin/benzoyl peroxide
2009:10.1158/0008-5472.CAN-15-1626
1879:Analogue-based Drug Discovery
1707:
3993:Clindamycin/benzoyl peroxide
2350:Food and Drug Administration
2115:Journal of Wildlife Diseases
2041:"Tetracycline hydrochloride"
1960:10.1016/j.celrep.2015.02.034
1667:chronic myelogenous leukemia
1586:
1511:
1439:Food and Drug Administration
1079:The following list presents
1072:leading to effects that may
1024:Rocky Mountain spotted fever
998:. They are also of value in
976:, anaerobes, members of the
7:
5681:Dodecylbenzenesulfonic acid
5440:Tooltip Pregnane X receptor
5168:Xenobiotic-sensing receptor
2960:Urquhart C (15 July 2012).
1647:
1216:reliable medical references
10:
6251:
4018:Tretinoin/benzoyl peroxide
3983:Adapalene/benzoyl peroxide
3058:Sodium monofluorophosphate
2127:10.7589/0090-3558-36.4.734
1670:experimentation or study.
1663:transcriptional activation
1661:, tetracycline is used in
1538:palladized carbon catalyst
1506:
1447:toxic epidermal necrolysis
1416:Affect bone growth of the
1318:Be inactivated by calcium
1192:
700:Chemical and physical data
29:
6137:
5433:
5177:
5102:
5064:
4961:
4878:
4833:Quinupristin/dalfopristin
4791:
4763:
4735:
4597:
4586:
4540:
4486:
4477:
4451:
4365:
4350:
4330:
4269:
4152:
4137:
4128:
4101:inhibit protein synthesis
4026:
4008:Erythromycin/isotretinoin
3975:
3939:
3896:
3833:
3780:
3747:
3714:
3676:
3601:
3523:
3480:
3471:
3368:
3334:
3325:
3232:
3198:
3071:
3030:
2887:"Aftermath Episode Recap"
1908:World Health Organization
1222:or relies too heavily on
817:
792:
772:
750:
737:
704:
699:
680:
648:
620:
600:
580:
560:
540:
520:
500:
475:
448:
428:
423:
413:
400:
390:
380:
372:
356:
351:
246:
232:
206:
176:
162:
144:
136:
126:
69:
64:
55:
46:
6230:Tetracycline antibiotics
6064:Testosterone isocaproate
5979:Reverse triiodothyronine
4352:Tetracycline antibiotics
3110:Cetylpyridinium chloride
1624:
1619:tetracycline antibiotics
1483:Mechanisms of resistance
1443:Stevens–Johnson syndrome
1308:tetracycline antibiotics
1056:, and nasal carriage of
32:Tetracycline antibiotics
5456:17α-Hydroxyprogesterone
5451:17α-Hydroxypregnenolone
4976:Aluminium acetotartrate
2776:10.1126/science.7001623
2598:10.1093/clinids/7.5.702
2376:Mehta A (27 May 2011).
2088:"Tetracycline Labeling"
1495:that either encodes an
931:bacterial genera, both
6195:Anti-acne preparations
5084:Fluocinolone acetonide
2931:10.1038/sj.leu.2402225
2380:. Pharmaxchange.info.
1162:
1112:: 1 μg/mL to 128 μg/mL
1076:experimental results.
942:Pseudomonas aeruginosa
419:Urine (>60%), feces
5195:6,7-Dimethylesculetin
3998:Clindamycin/tretinoin
1640:'s survival sandbox,
1560:Evidence in antiquity
1522:Yellapragada Subbarow
1518:Benjamin Minge Duggar
1413:, in some individuals
1384:Cause microvesicular
1363:, so exposure to the
1160:
1053:Mycoplasma pneumoniae
973:Neisseria gonorrhoeae
5782:Hypericum perforatum
5771:Hetacillin potassium
4981:Aluminium triacetate
4542:Peptidyl transferase
4013:Sulfacetamide/sulfur
3245:Acetylsalicylic acid
3090:Benzoxonium chloride
2098:on 15 December 2012.
2057:on 8 September 2015.
1810:U.S. patent 2699054A
1701:genetically modified
1526:Lederle Laboratories
1002:infections, such as
954:pathogenic organisms
919:Spectrum of activity
5611:Cyproterone acetate
5511:Amlodipine besylate
4171:Dihydrostreptomycin
3853:Cyproterone acetate
3490:Silver sulfadiazine
2768:1980Sci...209.1532B
2762:(4464): 1532–1534.
2684:10.1021/ja01114a537
2645:10.1021/ja01642a064
2404:"Tetracycline, USP"
1839:2011NYASA1241...17N
1659:genetic engineering
1653:Genetic engineering
1638:Bohemia Interactive
1582:Society and culture
1489:horizontal transfer
1466:Mechanism of action
1451:erythema multiforme
1374:Cause drug-induced
1185:-containing baits.
889:easily. Use during
43:
6190:1948 introductions
6084:Thonzonium bromide
5839:Methylprednisolone
5640:prasterone sulfate
4905:Never to phase III
4053:Never to phase III
3701:Blue light therapy
3696:8-Hydroxyquinoline
3667:-treating agents (
2897:on 13 October 2017
2711:Journal of Anatomy
2357:on 17 January 2011
1411:anaphylactic shock
1371:is not recommended
1337:Be inactivated by
1163:
1153:Use as a biomarker
1117:Anti-eukaryote use
978:Enterobacteriaceae
902:generic medication
39:
6155:
6154:
5789:Indinavir sulfate
5496:Alpha-Lipoic acid
5471:Δ-Androstenedione
5461:Δ-Androstenedione
5134:
5133:
5021:Hydrogen peroxide
4915:
4914:
4874:
4873:
4870:
4869:
4582:
4581:
4473:
4472:
4469:
4468:
4378:Chlortetracycline
4346:
4345:
4063:
4062:
3772:Red light therapy
3749:Anti-inflammatory
3631:
3630:
3627:
3626:
3473:Chemotherapeutics
3467:
3466:
3350:Chlortetracycline
3310:chemotherapeutics
3272:
3271:
3190:Tibezonium iodide
3135:Hydrogen peroxide
3100:Chlortetracycline
3063:Stannous fluoride
2925:(10): 1658–1662.
2678:(18): 4622–4623.
2639:(13): 3568–3575.
2520:(12): 3675–3681.
2303:. 15 August 2022.
2149:on 15 April 2013.
2076:on 12 March 2007.
2003:(21): 4446–4449.
1954:(10): 1681–1691.
1530:chlortetracycline
1441:(FDA), cases of
1304:
1303:
1280:
829:
828:
763:Interactive image
650:CompTox Dashboard
222:
189:
16:(Redirected from
6242:
6172:
6171:
6170:
6163:
6074:Thiamylal sodium
5809:γ-linolenic acid
5805:α-Linolenic acid
5803:Linolenic acid:
5794:Lasalocid sodium
5784:(St John's wort)
5676:Docusate calcium
5606:Cyclophosphamide
5481:Allopregnanediol
5466:Δ-Androstenediol
5441:
5437:
5395:Ethinylestradiol
5245:Cyclophosphamide
5185:
5181:
5161:
5154:
5147:
5138:
5137:
4985:Burow's solution
4942:
4935:
4928:
4919:
4918:
4595:
4594:
4547:
4546:
4484:
4483:
4433:Rolitetracycline
4363:
4362:
4150:
4149:
4135:
4134:
4090:
4083:
4076:
4067:
4066:
3886:Ethinylestradiol
3739:Benzoyl peroxide
3691:Benzoyl peroxide
3658:
3651:
3644:
3635:
3634:
3609:Ingenol mebutate
3478:
3477:
3332:
3331:
3299:
3292:
3285:
3276:
3275:
3180:Sodium perborate
3115:Domiphen bromide
3012:
3005:
2998:
2989:
2988:
2982:
2981:
2979:
2977:
2957:
2951:
2950:
2913:
2907:
2906:
2904:
2902:
2893:. Archived from
2883:
2877:
2876:
2847:
2841:
2840:
2838:
2836:
2816:
2807:
2806:
2794:
2788:
2787:
2751:
2745:
2744:
2734:
2702:
2696:
2695:
2663:
2657:
2656:
2624:
2618:
2617:
2581:
2575:
2574:
2572:
2570:
2561:. Archived from
2554:
2548:
2547:
2537:
2505:
2499:
2498:
2488:
2456:
2450:
2449:
2447:
2445:
2428:Todar K (2012).
2425:
2419:
2418:
2416:
2414:
2400:
2394:
2393:
2391:
2389:
2373:
2367:
2366:
2364:
2362:
2341:
2335:
2334:
2326:
2320:
2319:
2311:
2305:
2304:
2293:
2287:
2286:
2285:
2283:
2265:"Demeclocycline"
2261:
2255:
2254:
2252:
2250:
2227:
2216:
2215:
2187:
2181:
2180:
2178:
2176:
2157:
2151:
2150:
2145:. Archived from
2106:
2100:
2099:
2084:
2078:
2077:
2072:. Archived from
2065:
2059:
2058:
2056:
2045:
2037:
2031:
2030:
2020:
1988:
1982:
1981:
1971:
1939:
1933:
1930:
1924:
1923:
1904:
1898:
1897:
1873:
1867:
1866:
1822:
1813:
1812:
1806:
1800:
1799:
1797:
1795:
1780:
1757:
1756:
1739:
1733:
1732:
1730:
1728:
1718:
1552:, and later the
1453:associated with
1427:Fanconi syndrome
1361:photosensitivity
1299:
1298:
1290:
1287:
1281:
1279:
1238:
1207:
1206:
1199:
1111:
1101:to >128 μg/mL
1100:
1096:
1089:Escherichia coli
825:
824:
765:
745:
730:
724:
718:
712:
695:
684:
673:
672:
658:
656:
640:
634:
613:
593:
573:
553:
533:
513:
493:
483:
482:
468:
461:
405:
343:
333:
323:
313:
303:
293:
283:
273:
263:
220:
217:
199:
188:
185:
172:
158:
121:
120:
117:
116:
113:
110:
107:
104:
101:
98:
95:
92:
89:
86:
83:
80:
60:
51:
44:
42:
38:
21:
6250:
6249:
6245:
6244:
6243:
6241:
6240:
6239:
6205:Cancer research
6180:
6179:
6178:
6168:
6166:
6158:
6156:
6151:
6133:
6034:Suberoylanilide
5751:Fluorometholone
5646:Dibunate sodium
5526:Aurothioglucose
5439:
5429:
5365:3,17β-Estradiol
5183:
5173:
5165:
5135:
5130:
5098:
5066:Corticosteroids
5060:
4996:Chloramphenicol
4957:
4946:
4916:
4911:
4910:
4895:Clinical trials
4866:
4852:Streptogramin B
4847:Streptogramin A
4787:
4759:
4731:
4578:
4559:Chloramphenicol
4536:
4490:
4465:
4447:
4428:Penimepicycline
4423:Oxytetracycline
4354:
4342:
4326:
4265:
4141:
4139:Aminoglycosides
4124:
4094:
4064:
4059:
4058:
4043:Clinical trials
4022:
3971:
3935:
3892:
3829:
3776:
3743:
3710:
3672:
3662:
3632:
3623:
3597:
3563:Podophyllotoxin
3519:
3463:
3387:Aminoglycosides
3380:Chloramphenicol
3364:
3355:Oxytetracycline
3338:and derivatives
3321:
3303:
3273:
3268:
3228:
3205:Glucocorticoids
3202:
3200:Corticosteroids
3194:
3067:
3053:Sodium fluoride
3026:
3016:
2986:
2985:
2975:
2973:
2958:
2954:
2914:
2910:
2900:
2898:
2885:
2884:
2880:
2848:
2844:
2834:
2832:
2817:
2810:
2799:Natural History
2795:
2791:
2752:
2748:
2703:
2699:
2664:
2660:
2625:
2621:
2582:
2578:
2568:
2566:
2565:on 17 June 2007
2555:
2551:
2506:
2502:
2457:
2453:
2443:
2441:
2426:
2422:
2412:
2410:
2402:
2401:
2397:
2387:
2385:
2374:
2370:
2360:
2358:
2343:
2342:
2338:
2327:
2323:
2312:
2308:
2295:
2294:
2290:
2281:
2279:
2263:
2262:
2258:
2248:
2246:
2228:
2219:
2198:(10): 709–715.
2188:
2184:
2174:
2172:
2165:medlineplus.gov
2159:
2158:
2154:
2107:
2103:
2086:
2085:
2081:
2066:
2062:
2054:
2043:
2039:
2038:
2034:
1997:Cancer Research
1989:
1985:
1940:
1936:
1931:
1927:
1905:
1901:
1890:
1874:
1870:
1823:
1816:
1808:
1807:
1803:
1793:
1791:
1782:
1781:
1760:
1741:
1740:
1736:
1726:
1724:
1720:
1719:
1715:
1710:
1683:(the infection
1655:
1650:
1627:
1612:
1589:
1584:
1562:
1514:
1509:
1485:
1468:
1463:
1435:bioavailability
1402:Interfere with
1398:epigastric pain
1300:
1296:
1291:
1285:
1282:
1239:
1228:
1224:primary sources
1208:
1204:
1197:
1195:Tooth bleaching
1191:
1155:
1119:
921:
916:
883:kidney problems
820:
818:
813:
810:
805:
800:
799:
788:
785:
780:
779:
768:
743:
733:
727:
721:
715:
676:
652:
644:
616:
596:
576:
556:
536:
516:
496:
479:
471:
444:
441:
436:
435:
403:
396:Not metabolized
382:Bioavailability
374:Pharmacokinetic
368:
347:
235:
228:
209:
202:
77:
73:
35:
28:
23:
22:
15:
12:
11:
5:
6248:
6238:
6237:
6232:
6227:
6222:
6217:
6212:
6207:
6202:
6197:
6192:
6177:
6176:
6153:
6152:
6150:
6149:
6142:
6138:
6135:
6134:
6132:
6131:
6126:
6117:
6116:
6111:
6106:
6101:
6099:Troleandomycin
6096:
6091:
6086:
6081:
6076:
6071:
6066:
6061:
6056:
6051:
6046:
6041:
6036:
6031:
6026:
6021:
6019:Spironolactone
6016:
6011:
6006:
6001:
5996:
5991:
5986:
5981:
5976:
5971:
5966:
5961:
5956:
5951:
5946:
5941:
5936:
5931:
5926:
5921:
5916:
5911:
5906:
5901:
5896:
5891:
5889:Norelgestromin
5886:
5881:
5876:
5871:
5866:
5861:
5856:
5851:
5846:
5841:
5836:
5831:
5826:
5821:
5816:
5811:
5801:
5796:
5791:
5786:
5778:
5773:
5768:
5763:
5758:
5753:
5748:
5746:Flucloxacillin
5743:
5738:
5733:
5728:
5723:
5718:
5713:
5708:
5703:
5698:
5693:
5688:
5683:
5678:
5673:
5668:
5663:
5658:
5653:
5648:
5643:
5633:
5623:
5618:
5613:
5608:
5603:
5601:Corticosterone
5598:
5593:
5588:
5583:
5578:
5573:
5568:
5566:Chlorpromazine
5563:
5558:
5553:
5548:
5543:
5538:
5533:
5528:
5523:
5518:
5513:
5508:
5503:
5498:
5493:
5488:
5483:
5478:
5473:
5468:
5463:
5458:
5453:
5444:
5442:
5431:
5430:
5428:
5427:
5422:
5417:
5412:
5407:
5402:
5397:
5392:
5387:
5385:17-Androstanol
5382:
5380:3β-Androstanol
5377:
5375:3α-Androstenol
5372:
5370:3α-Androstanol
5367:
5358:
5357:
5352:
5347:
5342:
5337:
5332:
5327:
5322:
5317:
5312:
5307:
5302:
5297:
5292:
5287:
5282:
5277:
5272:
5267:
5262:
5252:
5247:
5242:
5237:
5232:
5227:
5225:Chlorpromazine
5222:
5217:
5212:
5207:
5202:
5197:
5188:
5186:
5175:
5174:
5164:
5163:
5156:
5149:
5141:
5132:
5131:
5129:
5128:
5123:
5118:
5112:
5110:
5100:
5099:
5097:
5096:
5091:
5089:Hydrocortisone
5086:
5081:
5076:
5070:
5068:
5062:
5061:
5059:
5058:
5053:
5048:
5043:
5038:
5033:
5028:
5023:
5018:
5013:
5008:
5003:
4998:
4993:
4988:
4978:
4973:
4967:
4965:
4959:
4958:
4945:
4944:
4937:
4930:
4922:
4913:
4912:
4909:
4908:
4907:
4906:
4903:
4892:
4886:
4880:
4879:
4876:
4875:
4872:
4871:
4868:
4867:
4865:
4864:
4854:
4849:
4844:
4830:
4816:
4797:
4795:
4793:Streptogramins
4789:
4788:
4786:
4785:
4780:
4775:
4769:
4767:
4761:
4760:
4758:
4757:
4752:
4747:
4741:
4739:
4733:
4732:
4730:
4729:
4724:
4719:
4714:
4712:Troleandomycin
4709:
4704:
4699:
4694:
4689:
4684:
4679:
4674:
4669:
4664:
4659:
4654:
4649:
4644:
4642:Flurithromycin
4639:
4634:
4629:
4627:Clarithromycin
4624:
4619:
4614:
4609:
4603:
4601:
4592:
4584:
4583:
4580:
4579:
4577:
4576:
4571:
4566:
4561:
4555:
4553:
4544:
4538:
4537:
4535:
4534:
4529:
4524:
4519:
4514:
4509:
4504:
4498:
4496:
4481:
4475:
4474:
4471:
4470:
4467:
4466:
4464:
4463:
4457:
4455:
4453:Glycylcyclines
4449:
4448:
4446:
4445:
4440:
4435:
4430:
4425:
4420:
4415:
4410:
4405:
4400:
4395:
4390:
4388:Demeclocycline
4385:
4380:
4375:
4369:
4367:
4360:
4348:
4347:
4344:
4343:
4341:
4340:
4334:
4332:
4328:
4327:
4325:
4324:
4319:
4313:
4312:
4311:
4310:
4305:
4300:
4295:
4290:
4279:
4277:
4273:Micromonospora
4267:
4266:
4264:
4263:
4261:Nourseothricin
4258:
4253:
4248:
4243:
4238:
4227:
4226:
4225:
4224:
4219:
4214:
4209:
4198:
4197:
4196:
4195:
4190:
4185:
4174:
4173:
4168:
4162:
4160:
4147:
4132:
4126:
4125:
4097:Antibacterials
4093:
4092:
4085:
4078:
4070:
4061:
4060:
4057:
4056:
4055:
4054:
4051:
4040:
4034:
4028:
4027:
4024:
4023:
4021:
4020:
4015:
4010:
4005:
4000:
3995:
3990:
3985:
3979:
3977:
3973:
3972:
3970:
3969:
3964:
3959:
3954:
3949:
3943:
3941:
3937:
3936:
3934:
3933:
3928:
3923:
3918:
3913:
3908:
3902:
3900:
3894:
3893:
3891:
3890:
3889:
3888:
3883:
3873:
3872:
3871:
3868:Spironolactone
3865:
3860:
3855:
3850:
3839:
3837:
3831:
3830:
3828:
3827:
3821:
3816:
3807:
3802:
3797:
3792:
3786:
3784:
3778:
3777:
3775:
3774:
3769:
3764:
3759:
3753:
3751:
3745:
3744:
3742:
3741:
3736:
3731:
3729:Salicylic acid
3726:
3720:
3718:
3712:
3711:
3709:
3708:
3703:
3698:
3693:
3688:
3682:
3680:
3674:
3673:
3661:
3660:
3653:
3646:
3638:
3629:
3628:
3625:
3624:
3622:
3621:
3616:
3611:
3605:
3603:
3599:
3598:
3596:
3595:
3590:
3585:
3580:
3575:
3570:
3565:
3560:
3555:
3550:
3545:
3540:
3535:
3529:
3527:
3521:
3520:
3518:
3517:
3512:
3507:
3505:Sulfamethizole
3502:
3497:
3492:
3486:
3484:
3475:
3469:
3468:
3465:
3464:
3462:
3461:
3456:
3451:
3446:
3437:
3436:
3426:
3425:
3415:
3414:
3404:
3403:
3398:
3393:
3383:
3382:
3372:
3370:
3366:
3365:
3363:
3362:
3357:
3352:
3347:
3345:Demeclocycline
3341:
3339:
3329:
3323:
3322:
3314:dermatological
3302:
3301:
3294:
3287:
3279:
3270:
3269:
3267:
3266:
3257:
3252:
3247:
3242:
3236:
3234:
3230:
3229:
3227:
3226:
3221:
3219:Hydrocortisone
3216:
3210:
3208:
3196:
3195:
3193:
3192:
3187:
3182:
3177:
3172:
3167:
3162:
3157:
3152:
3147:
3142:
3137:
3132:
3127:
3122:
3117:
3112:
3107:
3102:
3097:
3092:
3087:
3085:Amphotericin B
3081:
3079:
3069:
3068:
3066:
3065:
3060:
3055:
3050:
3045:
3039:
3037:
3028:
3027:
3021:preparations (
3019:Stomatological
3015:
3014:
3007:
3000:
2992:
2984:
2983:
2952:
2908:
2878:
2859:(8): 540–544.
2842:
2808:
2789:
2746:
2697:
2658:
2619:
2592:(5): 702–707.
2576:
2549:
2500:
2451:
2420:
2395:
2368:
2336:
2321:
2306:
2288:
2256:
2232:"Tetracycline"
2217:
2182:
2152:
2121:(4): 734–743.
2101:
2079:
2060:
2032:
1983:
1934:
1925:
1899:
1888:
1868:
1814:
1801:
1784:"Tetracycline"
1758:
1743:"Tetracycline"
1734:
1712:
1711:
1709:
1706:
1654:
1651:
1649:
1646:
1626:
1623:
1611:
1608:
1588:
1585:
1583:
1580:
1566:hydroxyapatite
1561:
1558:
1554:Glycylcyclines
1546:hydrogenolysis
1513:
1510:
1508:
1505:
1484:
1481:
1467:
1464:
1462:
1459:
1431:
1430:
1424:
1414:
1407:
1400:
1394:
1388:
1382:
1372:
1354:
1335:
1316:
1302:
1301:
1294:
1292:
1245:"Tetracycline"
1211:
1209:
1202:
1190:
1187:
1154:
1151:
1118:
1115:
1114:
1113:
1102:
1036:B. burgdorferi
959:Staphylococcus
920:
917:
915:
912:
827:
826:
815:
814:
812:
811:
808:
806:
803:
795:
794:
793:
790:
789:
787:
786:
783:
775:
774:
773:
770:
769:
767:
766:
758:
756:
748:
747:
741:
735:
734:
731:
725:
719:
713:
708:
702:
701:
697:
696:
686:
678:
677:
675:
674:
661:
659:
646:
645:
643:
642:
626:
624:
618:
617:
615:
614:
606:
604:
598:
597:
595:
594:
586:
584:
578:
577:
575:
574:
566:
564:
558:
557:
555:
554:
546:
544:
538:
537:
535:
534:
526:
524:
518:
517:
515:
514:
506:
504:
498:
497:
495:
494:
486:
484:
473:
472:
470:
469:
462:
454:
452:
446:
445:
443:
442:
439:
431:
430:
429:
426:
425:
421:
420:
417:
411:
410:
407:
398:
397:
394:
388:
387:
384:
378:
377:
370:
369:
367:
366:
362:
360:
354:
353:
349:
348:
346:
345:
252:
250:
244:
243:
238:
236:administration
230:
229:
227:
226:
224:
214:
212:
204:
203:
201:
200:
182:
180:
174:
173:
166:
160:
159:
152:
142:
141:
138:
134:
133:
130:
124:
123:
71:
67:
66:
62:
61:
53:
52:
26:
9:
6:
4:
3:
2:
6247:
6236:
6233:
6231:
6228:
6226:
6223:
6221:
6218:
6216:
6213:
6211:
6208:
6206:
6203:
6201:
6198:
6196:
6193:
6191:
6188:
6187:
6185:
6175:
6165:
6164:
6161:
6148:
6147:
6143:
6140:
6139:
6136:
6130:
6127:
6125:
6122:
6119:
6118:
6115:
6112:
6110:
6107:
6105:
6102:
6100:
6097:
6095:
6092:
6090:
6087:
6085:
6082:
6080:
6077:
6075:
6072:
6070:
6067:
6065:
6062:
6060:
6057:
6055:
6052:
6050:
6047:
6045:
6042:
6040:
6039:Sulfisoxazole
6037:
6035:
6032:
6030:
6027:
6025:
6022:
6020:
6017:
6015:
6012:
6010:
6007:
6005:
6002:
6000:
5997:
5995:
5992:
5990:
5987:
5985:
5982:
5980:
5977:
5975:
5972:
5970:
5967:
5965:
5962:
5960:
5957:
5955:
5952:
5950:
5947:
5945:
5942:
5940:
5937:
5935:
5932:
5930:
5927:
5925:
5922:
5920:
5917:
5915:
5914:Phenobarbital
5912:
5910:
5907:
5905:
5902:
5900:
5897:
5895:
5892:
5890:
5887:
5885:
5882:
5880:
5877:
5875:
5872:
5870:
5867:
5865:
5862:
5860:
5857:
5855:
5852:
5850:
5847:
5845:
5842:
5840:
5837:
5835:
5832:
5830:
5827:
5825:
5822:
5820:
5817:
5815:
5812:
5810:
5806:
5802:
5800:
5799:Levothyroxine
5797:
5795:
5792:
5790:
5787:
5785:
5783:
5779:
5777:
5774:
5772:
5769:
5767:
5764:
5762:
5761:Guggulsterone
5759:
5757:
5754:
5752:
5749:
5747:
5744:
5742:
5739:
5737:
5734:
5732:
5729:
5727:
5724:
5722:
5719:
5717:
5714:
5712:
5709:
5707:
5704:
5702:
5699:
5697:
5694:
5692:
5689:
5687:
5684:
5682:
5679:
5677:
5674:
5672:
5669:
5667:
5664:
5662:
5659:
5657:
5656:Dicloxacillin
5654:
5652:
5649:
5647:
5644:
5641:
5637:
5634:
5631:
5627:
5624:
5622:
5621:Dexamethasone
5619:
5617:
5614:
5612:
5609:
5607:
5604:
5602:
5599:
5597:
5594:
5592:
5589:
5587:
5584:
5582:
5579:
5577:
5574:
5572:
5569:
5567:
5564:
5562:
5559:
5557:
5556:Cephaloridine
5554:
5552:
5549:
5547:
5544:
5542:
5539:
5537:
5534:
5532:
5529:
5527:
5524:
5522:
5519:
5517:
5514:
5512:
5509:
5507:
5504:
5502:
5499:
5497:
5494:
5492:
5489:
5487:
5484:
5482:
5479:
5477:
5474:
5472:
5469:
5467:
5464:
5462:
5459:
5457:
5454:
5452:
5449:
5446:
5445:
5443:
5438:
5432:
5426:
5423:
5421:
5418:
5416:
5413:
5411:
5408:
5406:
5403:
5401:
5398:
5396:
5393:
5391:
5388:
5386:
5383:
5381:
5378:
5376:
5373:
5371:
5368:
5366:
5363:
5360:
5359:
5356:
5355:Valproic acid
5353:
5351:
5348:
5346:
5343:
5341:
5338:
5336:
5333:
5331:
5328:
5326:
5323:
5321:
5318:
5316:
5315:Phenobarbital
5313:
5311:
5308:
5306:
5303:
5301:
5298:
5296:
5293:
5291:
5288:
5286:
5283:
5281:
5278:
5276:
5273:
5271:
5268:
5266:
5263:
5260:
5256:
5253:
5251:
5248:
5246:
5243:
5241:
5238:
5236:
5233:
5231:
5228:
5226:
5223:
5221:
5218:
5216:
5215:Carbamazepine
5213:
5211:
5208:
5206:
5203:
5201:
5198:
5196:
5193:
5190:
5189:
5187:
5182:
5176:
5172:
5169:
5162:
5157:
5155:
5150:
5148:
5143:
5142:
5139:
5127:
5124:
5122:
5119:
5117:
5114:
5113:
5111:
5109:
5105:
5101:
5095:
5092:
5090:
5087:
5085:
5082:
5080:
5079:Dexamethasone
5077:
5075:
5074:Betamethasone
5072:
5071:
5069:
5067:
5063:
5057:
5054:
5052:
5049:
5047:
5044:
5042:
5039:
5037:
5036:Nitrofurazone
5034:
5032:
5029:
5027:
5024:
5022:
5019:
5017:
5014:
5012:
5009:
5007:
5006:Ciprofloxacin
5004:
5002:
5001:Chlorhexidine
4999:
4997:
4994:
4992:
4989:
4986:
4982:
4979:
4977:
4974:
4972:
4969:
4968:
4966:
4964:
4960:
4955:
4951:
4943:
4938:
4936:
4931:
4929:
4924:
4923:
4920:
4904:
4902:
4899:
4898:
4896:
4893:
4890:
4887:
4885:
4882:
4881:
4877:
4862:
4858:
4857:Virginiamycin
4855:
4853:
4850:
4848:
4845:
4842:
4838:
4834:
4831:
4828:
4824:
4820:
4817:
4814:
4810:
4806:
4802:
4801:Pristinamycin
4799:
4798:
4796:
4794:
4790:
4784:
4781:
4779:
4776:
4774:
4771:
4770:
4768:
4766:
4762:
4756:
4755:Solithromycin
4753:
4751:
4748:
4746:
4745:Telithromycin
4743:
4742:
4740:
4738:
4734:
4728:
4725:
4723:
4720:
4718:
4717:Tulathromycin
4715:
4713:
4710:
4708:
4705:
4703:
4700:
4698:
4697:Telithromycin
4695:
4693:
4690:
4688:
4687:Solithromycin
4685:
4683:
4682:Roxithromycin
4680:
4678:
4675:
4673:
4670:
4668:
4665:
4663:
4660:
4658:
4655:
4653:
4650:
4648:
4647:Gamithromycin
4645:
4643:
4640:
4638:
4635:
4633:
4632:Dirithromycin
4630:
4628:
4625:
4623:
4620:
4618:
4615:
4613:
4610:
4608:
4605:
4604:
4602:
4600:
4596:
4593:
4590:
4585:
4575:
4572:
4570:
4569:Thiamphenicol
4567:
4565:
4564:Azidamfenicol
4562:
4560:
4557:
4556:
4554:
4552:
4548:
4545:
4543:
4539:
4533:
4530:
4528:
4525:
4523:
4520:
4518:
4515:
4513:
4510:
4508:
4505:
4503:
4500:
4499:
4497:
4494:
4489:
4488:Oxazolidinone
4485:
4482:
4480:
4476:
4462:
4459:
4458:
4456:
4454:
4450:
4444:
4441:
4439:
4436:
4434:
4431:
4429:
4426:
4424:
4421:
4419:
4416:
4414:
4411:
4409:
4406:
4404:
4401:
4399:
4396:
4394:
4391:
4389:
4386:
4384:
4381:
4379:
4376:
4374:
4371:
4370:
4368:
4366:Tetracyclines
4364:
4361:
4358:
4353:
4349:
4339:
4336:
4335:
4333:
4329:
4323:
4320:
4318:
4315:
4314:
4309:
4306:
4304:
4301:
4299:
4296:
4294:
4291:
4289:
4286:
4285:
4284:
4281:
4280:
4278:
4275:
4274:
4268:
4262:
4259:
4257:
4254:
4252:
4249:
4247:
4244:
4242:
4241:Spectinomycin
4239:
4236:
4232:
4229:
4228:
4223:
4220:
4218:
4215:
4213:
4210:
4208:
4205:
4204:
4203:
4200:
4199:
4194:
4191:
4189:
4186:
4184:
4181:
4180:
4179:
4176:
4175:
4172:
4169:
4167:
4164:
4163:
4161:
4158:
4157:
4151:
4148:
4145:
4140:
4136:
4133:
4131:
4127:
4122:
4118:
4114:
4110:
4106:
4102:
4098:
4091:
4086:
4084:
4079:
4077:
4072:
4071:
4068:
4052:
4050:
4047:
4046:
4044:
4041:
4038:
4035:
4033:
4030:
4029:
4025:
4019:
4016:
4014:
4011:
4009:
4006:
4004:
4001:
3999:
3996:
3994:
3991:
3989:
3986:
3984:
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3978:
3974:
3968:
3965:
3963:
3960:
3958:
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3927:
3924:
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3919:
3917:
3914:
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3909:
3907:
3904:
3903:
3901:
3899:
3895:
3887:
3884:
3882:
3879:
3878:
3877:
3874:
3869:
3866:
3864:
3861:
3859:
3856:
3854:
3851:
3849:
3846:
3845:
3844:
3843:Antiandrogens
3841:
3840:
3838:
3836:
3832:
3825:
3822:
3820:
3817:
3815:
3811:
3810:Tetracyclines
3808:
3806:
3805:Sulfacetamide
3803:
3801:
3798:
3796:
3793:
3791:
3788:
3787:
3785:
3783:
3779:
3773:
3770:
3768:
3765:
3763:
3760:
3758:
3755:
3754:
3752:
3750:
3746:
3740:
3737:
3735:
3732:
3730:
3727:
3725:
3724:Glycolic acid
3722:
3721:
3719:
3717:
3713:
3707:
3704:
3702:
3699:
3697:
3694:
3692:
3689:
3687:
3684:
3683:
3681:
3679:
3678:Antibacterial
3675:
3670:
3666:
3659:
3654:
3652:
3647:
3645:
3640:
3639:
3636:
3620:
3617:
3615:
3614:Metronidazole
3612:
3610:
3607:
3606:
3604:
3600:
3594:
3591:
3589:
3586:
3584:
3581:
3579:
3576:
3574:
3571:
3569:
3566:
3564:
3561:
3559:
3556:
3554:
3551:
3549:
3546:
3544:
3541:
3539:
3536:
3534:
3531:
3530:
3528:
3526:
3522:
3516:
3515:Sulfamerazine
3513:
3511:
3510:Sulfanilamide
3508:
3506:
3503:
3501:
3498:
3496:
3495:Sulfathiazole
3493:
3491:
3488:
3487:
3485:
3483:
3479:
3476:
3474:
3470:
3460:
3457:
3455:
3452:
3450:
3447:
3445:
3442:
3439:
3438:
3435:
3431:
3428:
3427:
3424:
3423:Virginiamycin
3420:
3419:Streptogramin
3417:
3416:
3413:
3409:
3406:
3405:
3402:
3399:
3397:
3394:
3392:
3388:
3385:
3384:
3381:
3377:
3374:
3373:
3371:
3367:
3361:
3358:
3356:
3353:
3351:
3348:
3346:
3343:
3342:
3340:
3337:
3333:
3330:
3328:
3324:
3319:
3315:
3311:
3307:
3300:
3295:
3293:
3288:
3286:
3281:
3280:
3277:
3265:
3261:
3258:
3256:
3253:
3251:
3248:
3246:
3243:
3241:
3238:
3237:
3235:
3231:
3225:
3224:Triamcinolone
3222:
3220:
3217:
3215:
3214:Dexamethasone
3212:
3211:
3209:
3206:
3201:
3197:
3191:
3188:
3186:
3183:
3181:
3178:
3176:
3173:
3171:
3168:
3166:
3163:
3161:
3158:
3156:
3153:
3151:
3148:
3146:
3145:Metronidazole
3143:
3141:
3138:
3136:
3133:
3131:
3128:
3126:
3123:
3121:
3118:
3116:
3113:
3111:
3108:
3106:
3103:
3101:
3098:
3096:
3095:Chlorhexidine
3093:
3091:
3088:
3086:
3083:
3082:
3080:
3078:
3074:
3070:
3064:
3061:
3059:
3056:
3054:
3051:
3049:
3046:
3044:
3041:
3040:
3038:
3036:
3033:
3029:
3024:
3020:
3013:
3008:
3006:
3001:
2999:
2994:
2993:
2990:
2971:
2967:
2963:
2956:
2948:
2944:
2940:
2936:
2932:
2928:
2924:
2920:
2912:
2896:
2892:
2888:
2882:
2874:
2870:
2866:
2862:
2858:
2854:
2846:
2830:
2826:
2822:
2815:
2813:
2804:
2800:
2793:
2785:
2781:
2777:
2773:
2769:
2765:
2761:
2757:
2750:
2742:
2738:
2733:
2728:
2724:
2720:
2716:
2712:
2708:
2701:
2693:
2689:
2685:
2681:
2677:
2673:
2669:
2662:
2654:
2650:
2646:
2642:
2638:
2634:
2630:
2623:
2615:
2611:
2607:
2603:
2599:
2595:
2591:
2587:
2580:
2564:
2560:
2553:
2545:
2541:
2536:
2531:
2527:
2523:
2519:
2515:
2511:
2504:
2496:
2492:
2487:
2482:
2478:
2474:
2470:
2466:
2462:
2455:
2439:
2435:
2431:
2424:
2409:
2405:
2399:
2383:
2379:
2372:
2356:
2352:
2351:
2346:
2340:
2332:
2325:
2317:
2310:
2302:
2298:
2292:
2278:
2274:
2270:
2266:
2260:
2245:
2241:
2237:
2233:
2226:
2224:
2222:
2213:
2209:
2205:
2201:
2197:
2193:
2186:
2170:
2166:
2162:
2156:
2148:
2144:
2140:
2136:
2132:
2128:
2124:
2120:
2116:
2112:
2105:
2097:
2093:
2089:
2083:
2075:
2071:
2064:
2053:
2049:
2042:
2036:
2028:
2024:
2019:
2014:
2010:
2006:
2002:
1998:
1994:
1987:
1979:
1975:
1970:
1965:
1961:
1957:
1953:
1949:
1945:
1938:
1929:
1921:
1917:
1913:
1909:
1903:
1895:
1891:
1889:9783527607495
1885:
1881:
1880:
1872:
1864:
1860:
1856:
1852:
1848:
1844:
1840:
1836:
1832:
1828:
1821:
1819:
1811:
1805:
1789:
1785:
1779:
1777:
1775:
1773:
1771:
1769:
1767:
1765:
1763:
1754:
1750:
1749:
1744:
1738:
1723:
1717:
1713:
1705:
1704:into adults.
1702:
1698:
1694:
1690:
1686:
1682:
1681:
1680:Aedes aegypti
1676:
1671:
1668:
1664:
1660:
1645:
1643:
1639:
1634:
1632:
1622:
1620:
1615:
1607:
1604:
1600:
1596:
1595:
1579:
1576:
1574:
1569:
1567:
1557:
1555:
1551:
1547:
1543:
1539:
1535:
1531:
1527:
1523:
1519:
1504:
1502:
1498:
1494:
1490:
1480:
1477:
1473:
1458:
1456:
1452:
1448:
1444:
1440:
1436:
1428:
1425:
1423:
1419:
1415:
1412:
1408:
1405:
1401:
1399:
1395:
1393:
1389:
1387:
1383:
1381:
1377:
1373:
1370:
1366:
1362:
1359:
1355:
1352:
1348:
1344:
1340:
1336:
1333:
1329:
1325:
1321:
1317:
1313:
1312:
1311:
1309:
1293:
1289:
1286:November 2022
1278:
1275:
1271:
1268:
1264:
1261:
1257:
1254:
1250:
1247: –
1246:
1242:
1241:Find sources:
1236:
1232:
1226:
1225:
1221:
1217:
1212:This section
1210:
1201:
1200:
1196:
1186:
1184:
1180:
1175:
1173:
1168:
1159:
1150:
1148:
1144:
1143:balantidiasis
1140:
1136:
1132:
1129:caused by an
1128:
1124:
1108:
1107:
1103:
1092:
1090:
1086:
1085:
1084:
1082:
1077:
1075:
1071:
1066:
1065:peptic ulcers
1061:
1059:
1055:
1054:
1049:
1045:
1041:
1037:
1033:
1029:
1025:
1021:
1017:
1013:
1009:
1005:
1001:
997:
996:
991:
990:
985:
984:
979:
975:
974:
969:
967:
966:Streptococcus
962:
960:
955:
951:
949:
944:
943:
938:
937:Gram-negative
934:
933:Gram-positive
930:
926:
911:
909:
908:
903:
899:
894:
892:
888:
884:
880:
876:
871:
869:
865:
861:
857:
853:
849:
845:
841:
840:tetracyclines
837:
833:
823:
816:
807:
802:
801:
798:
791:
782:
781:
778:
771:
764:
760:
759:
757:
754:
749:
742:
740:
736:
709:
707:
703:
698:
694:
690:
687:
685:
683:ECHA InfoCard
679:
671:
667:
666:DTXSID7023645
663:
662:
660:
651:
647:
639:
638:RCSB PDB
633:
628:
627:
625:
623:
619:
612:
608:
607:
605:
603:
599:
592:
588:
587:
585:
583:
579:
572:
568:
567:
565:
563:
559:
552:
548:
547:
545:
543:
539:
532:
528:
527:
525:
523:
519:
512:
508:
507:
505:
503:
499:
492:
488:
487:
485:
478:
474:
467:
463:
460:
456:
455:
453:
451:
447:
438:
437:
434:
427:
422:
418:
416:
412:
408:
406:
399:
395:
393:
389:
385:
383:
379:
375:
371:
364:
363:
361:
359:
355:
350:
342:
337:
332:
327:
322:
317:
312:
307:
302:
297:
292:
287:
282:
277:
272:
267:
262:
257:
254:
253:
251:
249:
245:
242:
239:
237:
231:
225:
216:
215:
213:
211:
205:
198:
193:
184:
183:
181:
179:
175:
171:
167:
165:
161:
157:
153:
151:
147:
143:
140:TE/TET/TC/TCY
139:
135:
131:
129:
125:
119:
72:
70:Pronunciation
68:
65:Clinical data
63:
59:
54:
50:
45:
37:
33:
19:
6220:Hepatotoxins
6210:Carboxamides
6144:
6124:Ketoconazole
6121:Antagonists:
6120:
6094:Troglitazone
6069:Tetracycline
6068:
6024:Spiroxatrine
5969:Quingestrone
5964:Progesterone
5949:Pregnenolone
5944:Pregnanolone
5934:Pregnanediol
5929:Prednisolone
5854:Mifepristone
5781:
5756:Griseofulvin
5736:Fenbendazole
5721:Famprofazone
5716:Erythromycin
5711:Epothilone B
5696:Eburnamonine
5591:Clotrimazole
5581:Clofenvinfos
5516:Antimycotics
5447:
5410:Okadaic acid
5362:Antagonists:
5361:
5350:Troglitazone
5285:Mifepristone
5280:Methoxychlor
5275:Griseofulvin
5270:Ellagic acid
5250:Cypermethrin
5240:Clotrimazole
5191:
5094:Prednisolone
5056:Tetracycline
5055:
4841:Quinupristin
4837:Dalfopristin
4765:Lincosamides
4702:Tildipirosin
4672:Oleandomycin
4637:Erythromycin
4607:Azithromycin
4443:Tetracycline
4442:
4418:Omadacycline
4403:Meclocycline
4393:Eravacycline
4383:Clomocycline
4298:Micronomicin
4271:
4246:Hygromycin B
4235:+loteprednol
4193:Ribostamycin
4166:Streptomycin
4156:Streptomyces
4154:
3976:Combinations
3911:Isotretinoin
3858:Drospirenone
3848:Bicalutamide
3800:Erythromycin
3706:Tea tree oil
3686:Azelaic acid
3619:Tirbanibulin
3573:Tromantadine
3482:Sulfonamides
3444:Fusidic acid
3440:
3412:Nadifloxacin
3360:Tetracycline
3359:
3336:Tetracycline
3335:
3185:Tetracycline
3184:
3170:Oxyquinoline
3105:Clotrimazole
2974:. Retrieved
2966:The Observer
2965:
2955:
2922:
2918:
2911:
2899:. Retrieved
2895:the original
2891:SyFy Channel
2890:
2881:
2856:
2852:
2845:
2833:. Retrieved
2825:Boston Globe
2824:
2802:
2798:
2792:
2759:
2755:
2749:
2717:(1): 76–82.
2714:
2710:
2700:
2675:
2671:
2661:
2636:
2632:
2622:
2589:
2585:
2579:
2567:. Retrieved
2563:the original
2552:
2517:
2513:
2503:
2468:
2464:
2454:
2442:. Retrieved
2433:
2423:
2411:. Retrieved
2407:
2398:
2386:. Retrieved
2371:
2359:. Retrieved
2355:the original
2348:
2339:
2330:
2324:
2315:
2309:
2300:
2291:
2280:, retrieved
2268:
2259:
2247:. Retrieved
2235:
2195:
2191:
2185:
2173:. Retrieved
2164:
2155:
2147:the original
2118:
2114:
2104:
2096:the original
2091:
2082:
2074:the original
2063:
2052:the original
2047:
2035:
2000:
1996:
1986:
1951:
1948:Cell Reports
1947:
1937:
1928:
1920:10665/325771
1911:
1902:
1878:
1871:
1833:(1): 17–32.
1830:
1826:
1804:
1792:. Retrieved
1746:
1737:
1725:. Retrieved
1716:
1693:dengue fever
1689:yellow fever
1678:
1672:
1656:
1635:
1628:
1616:
1613:
1602:
1594:Boston Globe
1592:
1590:
1577:
1570:
1563:
1515:
1486:
1469:
1461:Pharmacology
1432:
1404:methotrexate
1330:, and other
1305:
1283:
1273:
1266:
1259:
1252:
1240:
1220:verification
1213:
1189:Side effects
1176:
1172:fluorescence
1164:
1120:
1104:
1087:
1078:
1070:mitochondria
1062:
1058:meningococci
1051:
1043:
1035:
1032:Lyme disease
1027:
1008:Lyme disease
1000:spirochaetal
993:
987:
981:
971:
965:
958:
947:
940:
922:
914:Medical uses
907:Streptomyces
905:
895:
872:
846:, including
832:Tetracycline
831:
830:
819:
402:Elimination
358:Legal status
352:Legal status
197:Tetracycline
178:License data
41:Tetracycline
36:
6225:Otologicals
6215:Dermatoxins
6109:Zafirlukast
6079:Thiothixene
6059:Terconazole
6009:Simvastatin
5884:Nisoldipine
5879:Nilvadipine
5864:Nicardipine
5834:Metacycline
5661:Dimercaprol
5616:Demecolcine
5576:Clindamycin
5571:Ciglitazone
5521:Artemisinin
5501:Ambrisentan
5405:Nigramide J
5340:Telmisartan
5300:Nicardipine
5210:Benfuracarb
5205:Artemisinin
5108:anesthetics
5046:Polymyxin B
4971:Acetic acid
4891:from market
4827:Linopristin
4773:Clindamycin
4750:Cethromycin
4677:Rokitamycin
4662:Midecamycin
4657:Kitasamycin
4574:Florfenicol
4551:Amphenicols
4495:inhibitors)
4461:Tigecycline
4438:Sarecycline
4413:Minocycline
4408:Metacycline
4398:Lymecycline
4373:Doxycycline
4217:Bekanamycin
4188:Paromomycin
4146:inhibitors)
4039:from market
3947:Epristeride
3931:Trifarotene
3916:Motretinide
3824:Doxycycline
3819:Minocycline
3814:Lymecycline
3790:Clindamycin
3782:Antibiotics
3757:Niacinamide
3716:Keratolytic
3588:Ibacitabine
3543:Idoxuridine
3538:Penciclovir
3454:Tyrothricin
3327:Antibiotics
3306:Antibiotics
3260:Epinephrine
3255:Benzydamine
3250:Becaplermin
3175:Polynoxylin
3155:Minocycline
3140:Mepartricin
3120:Doxycycline
3077:antiseptics
3035:prophylaxis
2835:18 November
2805:(4): 50–53.
2068:Mayton CA.
1610:Brand names
1550:Minocycline
1497:efflux pump
1455:doxycycline
1386:fatty liver
1367:or intense
1351:indigestion
1214:needs more
1048:psittacosis
1020:brucellosis
856:brucellosis
746: g·mol
689:100.000.438
591:CHEBI:27902
424:Identifiers
164:MedlinePlus
137:Other names
128:Trade names
6200:Biomarkers
6184:Categories
6089:Tianeptine
6054:Tenylidone
6049:Tacrolimus
5994:Rimexolone
5984:Rifampicin
5924:Plicamycin
5909:Paclitaxel
5894:Omeprazole
5874:Nifedipine
5849:Mevastatin
5844:Metyrapone
5824:Lovastatin
5819:Loratadine
5776:Hyperforin
5766:Haloprogin
5731:Felodipine
5706:Enzacamene
5686:Dronabinol
5651:Diclazuril
5630:prasterone
5586:Chloroxine
5561:Cephradine
5531:Bile acids
5345:Tolnaftate
5310:Permethrin
5295:Nevirapine
5290:Nefazodone
5259:prasterone
5220:Carvedilol
5200:Amiodarone
5171:modulators
5104:Analgesics
5026:Miconazole
5016:Gentamicin
5011:Clioquinol
4991:Boric acid
4823:Flopristin
4783:Pirlimycin
4778:Lincomycin
4727:Tylvalosin
4707:Tilmicosin
4692:Spiramycin
4667:Miocamycin
4622:Carrimycin
4617:Carbomycin
4599:Macrolides
4522:Ranbezolid
4502:Eperezolid
4493:initiation
4322:Astromicin
4317:Verdamicin
4308:Isepamicin
4303:Plazomicin
4288:Netilmicin
4283:Gentamicin
4231:Tobramycin
4183:Framycetin
4144:initiation
3921:Tazarotene
3558:Resiquimod
3525:Antivirals
3449:Bacitracin
3408:Quinolones
3396:Gentamicin
3376:Amphenicol
3264:Adrenalone
3150:Miconazole
3130:Hexetidine
2361:14 January
2236:StatPearls
1794:8 December
1708:References
1697:Zika fever
1256:newspapers
1193:See also:
1139:plasmodium
1123:eukaryotic
1028:Rickettsia
995:Rickettsia
989:Mycoplasma
887:sunburning
844:infections
836:antibiotic
751:3D model (
739:Molar mass
622:PDB ligand
611:ChEMBL1440
551:F8VB5M810T
522:ChemSpider
450:CAS Number
433:IUPAC name
392:Metabolism
6014:Sirolimus
6004:Ritonavir
5999:Riodipine
5989:Rifaximin
5974:Reserpine
5959:Proadifen
5904:Oxatomide
5859:Nafcillin
5829:Meclizine
5691:Droxidopa
5671:Docetaxel
5596:Colforsin
5546:Bumecaine
5536:Bithionol
5448:Agonists:
5425:T-0901317
5400:Meclizine
5330:Reserpine
5320:Phenytoin
5305:Octicizer
5265:Efavirenz
5192:Agonists:
5126:Phenazone
5116:Lidocaine
5051:Rifamycin
5041:Ofloxacin
4963:Infection
4901:Phase III
4889:Withdrawn
4737:Ketolides
4652:Josamycin
4612:Boromycin
4532:Tedizolid
4527:Sutezolid
4517:Radezolid
4512:Posizolid
4507:Linezolid
4338:Butirosin
4293:Sisomicin
4256:Apramycin
4251:Totomycin
4222:Dibekacin
4212:Arbekacin
4202:Kanamycin
4049:Phase III
4037:Withdrawn
3967:Tioxolone
3926:Tretinoin
3906:Adapalene
3898:Retinoids
3881:Estradiol
3876:Estrogens
3863:Flutamide
3762:Ibuprofen
3568:Docosanol
3553:Imiquimod
3548:Edoxudine
3533:Aciclovir
3459:Mupirocin
3434:Rifaximin
3430:Rifamycin
3240:Amlexanox
3160:Natamycin
3073:Infection
3043:Dectaflur
2692:0002-7863
2653:0002-7863
2557:Klajn R.
2444:27 August
1631:Aftermath
1587:Economics
1512:Discovery
1501:cytoplasm
1422:pregnancy
1380:hepatitis
1339:aluminium
1127:dysentery
983:Chlamydia
929:anaerobic
891:pregnancy
415:Excretion
404:half-life
234:Routes of
208:Pregnancy
156:Monograph
150:Drugs.com
6174:Medicine
6141:See also
6029:SR-12813
5919:Piperine
5899:Orlistat
5869:Nicotine
5741:Fentanyl
5726:Febantel
5701:Ecopipam
5666:Dinaline
5551:Cafestol
5541:Bosentan
5415:PK-11195
5031:Neomycin
4359:binding)
4270:-micin (
4207:Amikacin
4178:Neomycin
4153:-mycin (
3957:Pelretin
3952:Mesulfen
3835:Hormonal
3583:Lysozyme
3500:Mafenide
3401:Amikacin
3391:Neomycin
3165:Neomycin
2970:Archived
2947:40155100
2939:11587226
2919:Leukemia
2901:15 April
2829:Archived
2741:20456523
2544:14638464
2495:11381101
2438:Archived
2382:Archived
2282:20 March
2277:31644155
2249:19 March
2244:31751095
2212:15485524
2169:Archived
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2135:11085436
2027:26475870
1978:25772356
1910:(2019).
1894:Archived
1863:34647314
1855:22191524
1788:Archived
1677:species
1675:mosquito
1648:Research
1542:chemical
1392:tinnitus
1334:products
1179:wildlife
1167:biopsies
1106:Shigella
1074:confound
1044:Coxiella
1004:syphilis
875:diarrhea
868:syphilis
822:(verify)
531:10257122
502:DrugBank
491:54675776
336:QJ51AA07
326:QG51AA02
316:QG01AA90
248:ATC code
241:By mouth
210:category
192:DailyMed
132:Tetracyn
6129:Sesamin
6114:Zeranol
6044:Suramin
5814:LOE-908
5506:AMI-193
5420:S-07662
5335:TCPOBOP
5230:Chrysin
5121:Cocaine
4722:Tylosin
3962:Stridex
3795:Dapsone
3767:Aspirin
3578:Inosine
3125:Eugenol
3048:Olaflur
2976:15 July
2873:8971652
2784:7001623
2764:Bibcode
2756:Science
2732:2913014
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2569:20 June
2413:28 June
2018:4631686
1969:4565776
1835:Bibcode
1748:PubChem
1727:22 June
1540:. This
1507:History
1474:at the
1306:Use of
1270:scholar
1235:removed
1183:vaccine
1147:ciliate
1141:), and
1135:malaria
1040:Q fever
1012:anthrax
948:Proteus
925:aerobic
864:malaria
852:cholera
838:in the
744:444.440
706:Formula
511:DB00759
477:PubChem
466:64-75-5
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2602:JSTOR
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2139:S2CID
2055:(PDF)
2044:(PDF)
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1369:light
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1277:JSTOR
1263:books
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5807:and
5626:DHEA
5390:AITC
5255:DHEA
5106:and
4357:tRNA
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4113:J01F
4109:J01B
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3665:Acne
3312:for
3308:and
3075:and
2978:2012
2935:PMID
2903:2020
2869:PMID
2837:2015
2780:PMID
2737:PMID
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2571:2007
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2491:PMID
2446:2013
2415:2024
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2273:PMID
2251:2024
2240:PMID
2208:PMID
2177:2017
2131:PMID
2023:PMID
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2772:doi
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2123:doi
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