538:
515:
933:
4504:
47:
4516:
38:
883:. The IV push is often followed with a flush of 10ā20 mL of normal saline. If this has no effect (i.e., no evidence of transient AV block), a dose of 12 mg can be given 1ā2 minutes after the first dose. When given to dilate the arteries, such as in a "stress test", the dosage is typically 0.14 mg/kg/min, administered for 4 or 6 minutes, depending on the protocol.
1151:
activity. Researchers at
Cornell University have recently shown adenosine receptors to be key in opening the blood-brain barrier (BBB). Mice dosed with adenosine have shown increased transport across the BBB of amyloid plaque antibodies and prodrugs associated with Parkinson's disease, Alzheimer's,
966:
structure and bind to some of the same receptors as adenosine. Methylxanthines act as competitive antagonists of adenosine and can blunt its pharmacological effects. Individuals taking large quantities of methylxanthines may require increased doses of adenosine.
1414:, finding it was as potent as minoxidil (in overall treatment outcomes) but with higher satisfaction rate with patients due to āfaster prevention of hair loss and appearance of the newly grown hairsā (further trials were called for to clarify the findings).
2964:
Oura H, Iino M, Nakazawa Y, Tajima M, Ideta R, Nakaya Y, et al. (December 2008). "Adenosine increases anagen hair growth and thick hairs in
Japanese women with female pattern hair loss: a pilot, double-blind, randomized, placebo-controlled trial".
1218:
The administration of adenosine also reduces blood flow to coronary arteries past the occlusion. Other coronary arteries dilate when adenosine is administered while the segment past the occlusion is already maximally dilated, which is a process called
1379:'s stimulatory effects are credited primarily (although not entirely) to its capacity to block adenosine receptors, thereby reducing the inhibitory tonus of adenosine in the CNS. This reduction in adenosine activity leads to increased activity of the
1356:
has been shown in lab animals to drastically increase tissue repair and reconstruction. Topical administration of adenosine for use in wound-healing deficiencies and diabetes mellitus in humans is currently under clinical investigation.
5879:
2528:
Miller-Patrick K, Vincent DL, Early RJ, Weems YS, Tanaka Y, Ashimine DT, et al. (1993). "Effects of the purine biosynthesis pathway inhibitors azaserine, hadacidin, and mycophenolic acid on the developing ovine corpus luteum".
3049:
Faghihi G, Iraji F, Rajaee
Harandi M, Nilforoushzadeh MA, Askari G (2013). "Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenetic alopecia and measuring patient satisfaction rate".
985:. Caffeine also increases cyclic AMP levels through nonselective inhibition of phosphodiesterase. "Caffeine has a three-dimensional structure similar to that of adenosine," which allows it to bind and block its receptors.
1207:, subsequently inhibiting Ca current. It also causes endothelial-dependent relaxation of smooth muscle as is found inside the artery walls. This causes dilation of the "normal" segments of arteries, i.e. where the
1052:
tissue), these concentrations are quickly elevated (600ā1,200 nM). Thus, in regard to stress or injury, the function of adenosine is primarily that of cytoprotection preventing tissue damage during instances of
1833:
O'Keefe JH, Bateman TM, Silvestri R, Barnhart C (September 1992). "Safety and diagnostic accuracy of adenosine thallium-201 scintigraphy in patients unable to exercise and those with left bundle branch block".
3010:"Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles"
829:), and do not involve the AV node as part of the re-entrant circuit, are not typically converted by adenosine. However, the ventricular response rate is temporarily slowed with adenosine in such cases.
7399:
6948:
6518:
3795:
6928:
7078:
7088:
7048:
6893:
6888:
6903:
5884:
4553:
3236:
Sato A, Terata K, Miura H, Toyama K, Loberiza FR, Hatoum OA, et al. (April 2005). "Mechanism of vasodilation to adenosine in coronary arterioles from patients with heart disease".
2018:
Carter AJ, O'Connor WT, Carter MJ, Ungerstedt U (May 1995). "Caffeine enhances acetylcholine release in the hippocampus in vivo by a selective interaction with adenosine A1 receptors".
7203:
5855:
607:
6685:
886:
The recommended dose may be increased in patients on theophylline since methylxanthines prevent binding of adenosine at receptor sites. The dose is often decreased in patients on
6066:
4877:
4809:
1017:
Adenosine is an endogenous purine nucleoside that modulates many physiological processes. Cellular signaling by adenosine occurs through four known adenosine receptor subtypes (
1008:. This is being contested, and it is now considered a relative contraindication (however, selective adenosine antagonists are being investigated for use in treatment of asthma)
5101:
4954:
7826:
7296:
6508:
1215:. This feature allows physicians to use adenosine to test for blockages in the coronary arteries, by exaggerating the difference between the normal and abnormal segments.
5096:
5086:
7158:
6933:
6690:
4997:
4920:
1745:
Mitchell J, Lazarenko G (November 2008). "Wide QRS complex tachycardia. Diagnosis: Supraventricular tachycardia with aberrant conduction; intravenous (IV) adenosine".
7068:
6913:
6483:
4969:
4546:
7888:
6001:
8115:
7729:
6973:
128:
5770:
8434:
8505:
8155:
6558:
6538:
5869:
8510:
7933:
6478:
4539:
665:
1065:
receptors produces a constellation of responses that in general can be classified as anti-inflammatory. Enzymatic production of adenosine can be anti-
7883:
7223:
6802:
4766:
1048:
Extracellular adenosine concentrations from normal cells are approximately 300 nM; however, in response to cellular damage (e.g., in inflammatory or
8280:
8040:
7873:
7819:
5823:
8429:
8095:
7123:
6643:
6528:
6381:
5138:
4340:
8275:
8140:
7118:
7113:
6938:
6755:
6700:
6386:
6181:
6136:
6036:
6006:
5874:
5864:
4761:
4344:
8165:
8075:
8055:
7988:
7953:
7943:
7913:
6797:
6628:
6623:
6201:
6196:
6031:
6026:
6021:
6016:
5996:
5933:
5928:
77:
1426:. Adenosine levels rise during periods of wakefulness and lowers during sleep. Higher adenosine levels correlate with a stronger feeling of
8335:
8220:
8160:
8045:
7963:
7958:
7923:
7533:
7108:
6898:
6807:
6421:
6411:
6296:
5958:
5908:
4360:
4104:
3152:
2617:"A 7-deaza-adenosine analog is a potent and selective inhibitor of hepatitis C virus replication with excellent pharmacokinetic properties"
621:
844:
for a few seconds. This can be disconcerting to a normally conscious patient, and is associated with angina-like sensations in the chest.
8414:
8409:
8392:
8382:
8340:
8205:
8195:
8150:
8105:
8065:
8060:
8030:
7973:
7835:
7812:
7028:
6988:
6908:
6780:
6680:
6568:
6211:
4466:
4355:
3378:
8473:
8424:
8285:
8245:
7321:
7316:
7306:
7218:
7188:
7183:
7178:
7173:
7168:
7163:
7038:
7033:
7018:
7013:
7008:
7003:
6998:
6993:
6845:
6720:
6695:
6613:
6608:
6603:
6598:
6593:
6563:
6426:
6356:
6351:
6276:
6271:
6256:
6251:
6146:
6121:
6091:
5978:
5973:
5963:
894:(Valium) because adenosine potentiates the effects of these drugs. The recommended dose is also reduced by half in patients presenting
7098:
8448:
8443:
8175:
8125:
8120:
7326:
7138:
6346:
6341:
5953:
4332:
1431:
1442:
to raise and regulate adenosine levels in the body, for the intended promotion of consistent and sustained sleep in the long term.
649:
InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
8315:
8310:
8305:
8300:
8130:
8100:
8035:
7198:
7193:
7093:
7023:
6745:
6740:
6735:
6730:
6725:
6588:
6548:
6336:
6331:
5968:
5763:
4350:
1406:
Adenosine has been shown to promote thickening of hair on people with thinning hair. A 2013 study compared topical adenosine with
7133:
7063:
6812:
6775:
6705:
6523:
4370:
879:. Due to adenosine's extremely short half-life, the IV line is started as proximal (near) to the heart as possible, such as the
6817:
4380:
4220:
1698:"Electrophysiologic effects of adenosine triphosphate and adenosine on the mammalian heart: clinical and experimental aspects"
7424:
7346:
7283:
5714:
2512:
2462:
2097:
8495:
8255:
5589:
4375:
4192:
3496:
2299:"The Good, the Bad and the Unknown of CD38 in the Metabolic Microenvironment and Immune Cell Functionality of Solid Tumors"
1525:
1168:
875:(SVT), the initial dose is 6 mg to 12 mg, depending on standing orders or provider preference, given as a rapid
5756:
5131:
4460:
4390:
4365:
826:
686:
8515:
6161:
6141:
2000:
3179:
1817:
1586:
1561:
860:
672:
641:
2782:"Treating lung inflammation with agonists of the adenosine A2A receptor: promises, problems and potential solutions"
8540:
8210:
5731:
4215:
4157:
4097:
1264:
4454:
4394:
4167:
3371:
272:
187:
8500:
7998:
5124:
4900:
4895:
4442:
4436:
1274:
1223:. This leads to less blood reaching the ischemic tissue, which in turn produces the characteristic chest pain.
799:
733:
1203:, inhibiting adenylyl cyclase, reducing cAMP and so causing cell hyperpolarization by increasing K efflux via
363:
7053:
4519:
4424:
4407:
3465:
5350:
876:
7794:
5492:
5487:
5438:
5433:
5355:
5297:
5244:
5189:
5185:
5038:
4852:
4847:
4448:
4430:
4413:
4162:
3815:
3790:
3430:
1869:
1520:
872:
784:
533:
414:
5632:
5169:
1107:. The four receptor subtypes are further classified based on their ability to either stimulate or inhibit
7058:
6958:
5076:
5071:
4867:
4507:
4090:
3197:"Anandamide enhances extracellular levels of adenosine and induces sleep: an in vivo microdialysis study"
1104:
494:
8530:
7266:
7103:
6503:
5091:
4987:
4982:
4872:
4862:
4132:
3364:
2721:
Nakav S, Chaimovitz C, Sufaro Y, Lewis EC, Shaked G, Czeiger D, et al. (May 2008). Bozza P (ed.).
3126:
483:
5359:
5002:
3883:
3570:
3501:
7908:
7898:
4829:
3820:
895:
795:
510:
2664:
Warren TK, Wells J, Panchal RG, Stuthman KS, Garza NL, Van
Tongeren SA, et al. (April 2014).
2615:
Olsen DB, Eldrup AB, Bartholomew L, Bhat B, Bosserman MR, Ceccacci A, et al. (October 2004).
1900:"Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension"
1336:
viruses. Such adenosine analogs are potentially clinically useful since they can be taken orally.
7856:
7699:
7649:
6498:
5983:
5903:
5790:
5719:
5470:
5442:
5058:
5016:
4857:
4804:
4799:
3933:
3825:
3491:
1243:
832:
Because of the effects of adenosine on AV node-dependent SVTs, adenosine is considered a class V
116:
59:
1316:
and prevents lethality in infected animals, raising the possibility of a new treatment for this
7709:
7674:
7659:
7507:
7128:
6943:
6543:
6513:
6461:
6131:
6051:
5918:
5174:
5081:
5033:
5028:
4819:
4638:
4147:
3938:
3805:
3785:
3750:
3650:
2211:
HaskĆ³ G, Cronstein BN (January 2004). "Adenosine: an endogenous regulator of innate immunity".
1453:
1372:
1212:
1032:
1025:
911:
729:
221:
3195:
Murillo-Rodriguez E, Blanco-Centurion C, Sanchez C, Piomelli D, Shiromani PJ (December 2003).
463:
8535:
8013:
7754:
7724:
7704:
7684:
7654:
6953:
6923:
6533:
6493:
5898:
5796:
5600:
5557:
5048:
4992:
4949:
4944:
4814:
4488:
4259:
4232:
3928:
3845:
3460:
2666:"Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430"
2450:
1411:
1333:
1196:
1192:
1039:
1018:
974:
899:
833:
791:
696:
that occurs widely in nature in the form of diverse derivatives. The molecule consists of an
354:
259:
can leave cell intact or can be degraded to hypoxanthine, xanthine, and ultimately uric acid
8520:
8458:
7764:
7734:
7679:
7549:
7073:
6978:
6855:
6833:
6573:
6071:
6061:
5147:
5053:
5043:
4964:
4265:
4142:
4127:
3855:
3830:
3450:
3445:
2918:
2734:
2677:
2569:
1449:
863:(nuclear stress test) in patients unable to undergo adequate stress testing with exercise.
423:
403:
241:
1267:, allows adenosine to accumulate in the blood stream. This causes an increase in coronary
728:), which are essential for all life on Earth. Its derivatives include the energy carriers
8:
8215:
7878:
7759:
7248:
7043:
6850:
5938:
5478:
5254:
4959:
4839:
4728:
4631:
4244:
4238:
4226:
1483:
1329:
1291:
1250:
1239:
1175:, unlike other agonists of this receptor, adenosine is unable to induce the secretion of
940:
903:
814:
737:
309:
3320:
Morgan JM, McCormack DG, Griffiths MJ, Morgan CJ, Barnes PJ, Evans TW (September 1991).
2922:
2738:
2681:
2573:
537:
514:
318:
7848:
7272:
6456:
5838:
5782:
5618:
4705:
4418:
4322:
4113:
3835:
3676:
3655:
3604:
3261:
3171:
3103:
3079:"Adenosine, caffeine, and sleep-wake regulation: state of the science and perspectives"
3078:
2990:
2882:
2873:
2858:"Caffeine induces dopamine and glutamate release in the shell of the nucleus accumbens"
2857:
2806:
2781:
2757:
2722:
2698:
2665:
2592:
2557:
2423:
2398:
2374:
2349:
2325:
2298:
2274:
2247:
2188:
2163:
2139:
2114:
2070:
1926:
1899:
1727:
1643:
1515:
1082:
803:
758:) is the chemical group formed by removal of the 5ā²-hydroxy (OH) group. It is found in
741:
95:
64:
Adenocard; Adenocor; Adenic; Adenoco; Adeno-Jec; Adenoscan; Adenosin; Adrekar; Krenosin
2641:
2616:
1714:
1697:
1135:, which has been reported to mediate adenosine inhibition of Ca conductance, whereas A
7903:
7804:
7601:
6827:
4915:
4887:
4317:
4152:
4137:
3645:
3619:
3343:
3302:
3253:
3218:
3175:
3108:
3059:
3031:
2982:
2978:
2946:
2941:
2906:
2887:
2838:
2811:
2780:
Trevethick MA, Mantell SJ, Stuart EF, Barnard A, Wright KN, Yeadon M (October 2008).
2762:
2703:
2646:
2632:
2597:
2538:
2508:
2458:
2428:
2379:
2330:
2279:
2228:
2193:
2144:
2093:
2074:
2062:
2027:
1982:
1931:
1851:
1847:
1813:
1784:
1754:
1719:
1678:
1635:
1582:
1557:
1439:
1353:
1345:
1321:
1204:
1108:
1070:
1054:
907:
880:
822:
759:
2994:
1731:
1647:
1390:. Experimental evidence suggests that adenosine and adenosine agonists can activate
8525:
7468:
7457:
6670:
6663:
6633:
6111:
6056:
5208:
4685:
4049:
4006:
3800:
3387:
3333:
3292:
3245:
3208:
3167:
3098:
3090:
3021:
2974:
2936:
2926:
2877:
2869:
2801:
2793:
2752:
2742:
2693:
2685:
2636:
2628:
2587:
2577:
2556:
Yin Z, Chen YL, Schul W, Wang QY, Gu F, Duraiswamy J, et al. (December 2009).
2418:
2414:
2410:
2369:
2361:
2320:
2310:
2269:
2259:
2220:
2183:
2175:
2134:
2126:
2054:
1972:
1962:
1921:
1911:
1843:
1709:
1670:
1625:
1615:
1549:
1487:
1423:
1380:
1232:
1005:
994:
810:
693:
550:
203:
162:
141:
2856:
Solinas M, FerrƩ S, You ZB, Karcz-Kubicha M, Popoli P, Goldberg SR (August 2002).
343:
7414:
6822:
6790:
6765:
6316:
6216:
5923:
5779:
5678:
5669:
5160:
4675:
4604:
4001:
3265:
2747:
2365:
2058:
1898:
Saygin D, Tabib T, Bittar HE, Valenzi E, Sembrat J, Chan SY, et al. (2005).
1472:
1468:
1446:
947:
709:
231:
211:
172:
87:
5151:
3249:
3194:
3008:
Hwang KA, Hwang YL, Lee MH, Kim NR, Roh SS, Lee Y, et al. (February 2012).
2451:"Role of the Growth Hormone Secretagogue Receptor in the Central Nervous System"
2399:"Adenosine receptor signaling modulates permeability of the blood-brain barrier"
1363:'s anti-inflammatory effect may be due to its stimulation of adenosine release.
1320:. The 7-deaza-adenosine analog has been shown to inhibit the replication of the
7893:
7845:
7501:
7404:
7364:
6306:
6221:
5725:
5574:
5116:
4791:
4741:
4736:
4657:
4249:
4211:
4200:
4063:
3681:
3624:
3589:
3455:
2911:
Proceedings of the
National Academy of Sciences of the United States of America
2562:
Proceedings of the
National Academy of Sciences of the United States of America
2164:"Adenosine receptors: therapeutic aspects for inflammatory and immune diseases"
2045:
Faudone G, Arifi S, Merk D (June 2021). "The
Medicinal Chemistry of Caffeine".
1776:
1620:
1603:
1301:
1268:
1254:
1220:
1176:
857:
818:
721:
2478:
1661:
DelacrƩtaz E (March 2006). "Clinical practice. Supraventricular tachycardia".
790:
Certain SVTs can be successfully terminated with adenosine. This includes any
8489:
7491:
6648:
6401:
6321:
6081:
5748:
4910:
4905:
4824:
4756:
4695:
4177:
4054:
3981:
3696:
3425:
3338:
3321:
3297:
3280:
3213:
3196:
2224:
1148:
982:
837:
526:
153:
4531:
2582:
2004:
8377:
8110:
7928:
7774:
7714:
7611:
7596:
7591:
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7518:
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7409:
7379:
7336:
6877:
6406:
6301:
6186:
6171:
5609:
5496:
5223:
5203:
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4594:
4562:
4172:
4035:
4015:
3870:
3737:
3660:
3562:
3257:
3222:
3112:
3063:
3035:
2986:
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2931:
2891:
2842:
2815:
2766:
2707:
2650:
2601:
2432:
2383:
2334:
2283:
2232:
2197:
2148:
2066:
1986:
1935:
1788:
1758:
1682:
1639:
1544:
Butler P, KrƤutler B (2006). "Biological
Organometallic Chemistry of B12".
1503:
1502:
It also plays a role in regulation of blood flow to various organs through
1480:
1391:
1360:
1305:
1260:
1066:
955:
926:
887:
136:
3522:
3347:
3306:
3026:
3009:
2907:"Activation of Trk neurotrophin receptors in the absence of neurotrophins"
2542:
2031:
1967:
1950:
1855:
1723:
29:
8397:
8355:
8350:
8345:
8330:
8235:
8230:
8090:
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7586:
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7486:
7481:
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7394:
7359:
7243:
7148:
6750:
6441:
6416:
6396:
6371:
6366:
6311:
6116:
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6011:
5991:
5807:
5579:
5515:
5423:
5393:
5336:
5321:
4307:
4271:
3860:
3532:
3435:
3048:
2797:
2315:
2264:
2246:
Sek K, MĆølck C, Stewart GD, Kats L, Darcy PK, Beavis PA (December 2018).
1916:
1674:
1630:
1491:
1476:
1308:
by terminating its RNA chain synthesis. This interaction suppresses peak
1208:
1188:
959:
932:
767:
763:
2723:"Anti-inflammatory preconditioning by agonists of adenosine A1 receptor"
2689:
2130:
383:
8387:
8372:
8360:
8325:
8290:
8225:
8135:
8085:
8080:
8070:
7948:
7606:
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7538:
7523:
7513:
7369:
7331:
7238:
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6151:
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6041:
5948:
5640:
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5331:
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5279:
5218:
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4713:
4648:
4611:
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3810:
3691:
3686:
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3614:
3395:
1456:
1427:
1317:
1161:
929:
potentiates the action of adenosine, requiring the use of lower doses.
713:
583:
394:
3850:
3094:
1977:
1494:
to induce sleep in conditions where sleep may be severely attenuated.
1434:(CBT-I), which is considered one of the most effective treatments for
8402:
7694:
7560:
7528:
7384:
7311:
7213:
7153:
7143:
6963:
6715:
6391:
6376:
6361:
6176:
6126:
6101:
5943:
5686:
5655:
5650:
5645:
5614:
5540:
5456:
5451:
5418:
5403:
5378:
5373:
5306:
5284:
5274:
5260:
5233:
5228:
5213:
4746:
4670:
4402:
4254:
4082:
3723:
3629:
3542:
1553:
1407:
1387:
329:
254:
81:
46:
3356:
2829:
Cronstein B (2010). "How does methotrexate suppress inflammation?".
2179:
1300:
has been reported to directly inhibit the recombinant RNA-dependent
840:
an abnormal rhythm, it is normal for the heart to enter ventricular
8200:
7938:
7669:
7664:
7555:
7228:
6785:
6266:
6261:
6246:
6226:
6206:
6106:
5913:
5604:
5530:
5510:
5198:
4690:
4626:
4599:
4312:
4302:
4297:
3840:
3704:
3609:
3420:
1832:
1548:. Topics in Organometallic Chemistry. Vol. 17. pp. 1ā55.
1435:
1383:
1376:
1313:
1172:
1058:
1049:
970:
951:
936:
891:
853:
841:
443:
374:
3281:"Role of nitric oxide in adenosine-induced vasodilation in humans"
2479:"ŠŠ“ŠµŠ½Š¾Š·ŠøŠ½ Š² ŠŗŠ¾ŃŠ¼ŠµŃŠøŠŗŠµ - ŠŠ¾Š»ŃŠ·Š° Š°Š½ŃŠøŠ²Š¾Š·ŃŠ°ŃŃŠ½Š¾Š¹ ŠŗŠ¾ŃŠµŠ¹ŃŠŗŠ¾Š¹ ŠŗŠ¾ŃŠ¼ŠµŃŠøŠŗŠø"
2017:
1187:
When it is administered intravenously, adenosine causes transient
787:(SVT), adenosine is used to help identify and convert the rhythm.
606:
8295:
7778:
7749:
7719:
7689:
7639:
7389:
7374:
7233:
6983:
6862:
6840:
6638:
6086:
5828:
5811:
5696:
5691:
5622:
5535:
5505:
5473:
5413:
5268:
4700:
4680:
4621:
4589:
4584:
4040:
3956:
3552:
3537:
3527:
3517:
3470:
3440:
2397:
Carman AJ, Mills JH, Krenz A, Kim DG, Bynoe MS (September 2011).
1394:
phosphorylation through a mechanism that requires the adenosine A
1325:
1309:
1297:
1164:
915:
697:
22:
3238:
American
Journal of Physiology. Heart and Circulatory Physiology
2248:"Targeting Adenosine Receptor Signaling in Cancer Immunotherapy"
1602:
Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K (July 2018).
8320:
7744:
7739:
7451:
6658:
6653:
6618:
6326:
5398:
4616:
4579:
4182:
3547:
3475:
2527:
1155:
1152:
multiple sclerosis, and cancers of the central nervous system.
1001:
963:
701:
474:
3322:"Adenosine as a vasodilator in primary pulmonary hypertension"
3319:
2779:
2455:
Brain
Somatic Cross-Talk and the Central Control of Metabolism
7425:
7347:
7284:
7208:
6770:
6710:
6291:
6286:
6281:
3769:
3575:
1460:
1127:, which stimulates adenylate cyclase activity. In addition, A
597:
454:
5168:
2855:
1249:
When adenosine enters the circulation, it is broken down by
499:
6867:
6578:
6191:
6156:
2162:
HaskĆ³ G, Linden J, Cronstein B, Pacher P (September 2008).
1604:"Pharmacology of Adenosine Receptors: The State of the Art"
1352:
receptor. Topical treatment of adenosine to foot wounds in
434:
37:
2720:
2663:
2614:
2161:
740:. Adenosine is used as an intravenous medication for some
8014:
2020:
The Journal of Pharmacology and Experimental Therapeutics
1601:
1464:
725:
717:
8176:
2453:. In Kordon C, Robinson I, Hanoune J, Dantzer R (eds.).
2347:
1897:
236:
Rapidly converted to inosine and adenosine monophosphate
177:
Rapidly converted to inosine and adenosine monophosphate
2457:. Springer Science & Business Media. pp. 42ā.
249:
cleared plasma <30 seconds; half-life <10 seconds
216:
Rapidly cleared from circulation via enzyme degradation
109:(adenosine may be safe to the fetus in pregnant women)
7999:
7834:
2963:
1774:
1371:
In general, adenosine has an inhibitory effect in the
3235:
3076:
2444:
2442:
2348:
Antonioli L, Pacher P, Vizi ES, HaskĆ³ G (June 2013).
2087:
8459:
7840:
3151:
Perlis M, Shaw PJ, Cano G, Espie CA (January 2011).
2296:
2092:(2 ed.). Macmillan Learning. pp. 102ā103.
8256:
3150:
2558:"An adenosine nucleoside inhibitor of dengue virus"
2396:
2297:Konen JM, Fradette JJ, Gibbons DL (December 2019).
2245:
1422:Adenosine is a key factor in regulating the body's
1246:(AMP), though it is possible other pathways exist.
809:Fast rhythms of the heart that are confined to the
362:
5880:4'-O-Ī²-D-Glucosyl-9-O-(6''-deoxysaccharosyl)olivil
2448:
2439:
7909:Placental growth hormone (growth hormone variant)
3974:
3077:Reichert CF, Deboer T, Landolt HP (August 2022).
1744:
981:, which enhances release of the neurotransmitter
794:that require the AV node for the re-entry, e.g.,
8487:
5146:
3007:
2555:
2044:
1948:
871:When given for the evaluation or treatment of a
342:
4341:International Federation for Emergency Medicine
3994:
3918:
3778:
2088:Hillis DM, Sadava D, Hill RW, Price MV (2015).
2003:. R&S Pharmchem. April 2011. Archived from
1695:
1471:. These components also significantly increase
1430:, also known as sleep drive or sleep pressure.
1339:
778:
317:
6462:
5778:
4345:International Conference on Emergency Medicine
3278:
2210:
2112:
1807:
1783:. Treasure Island, FL: StatPearls Publishing.
1581:(4th ed.). New York: W. H. Freeman.
1543:
300:-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
7820:
7430:Tooltip Plasma membrane monoamine transporter
7352:Tooltip Equilibrative nucleoside transporters
7289:Tooltip Concentrative nucleoside transporters
5764:
5677:
5132:
4561:
4547:
4098:
3372:
1775:Goyal A, Basit H, Bhyan P, Zeltser R (2022).
1702:Journal of the American College of Cardiology
973:acts by blocking binding of adenosine to the
4361:Canadian Association of Emergency Physicians
3229:
3001:
2957:
2898:
2822:
2773:
2714:
2350:"CD39 and CD73 in immunity and inflammation"
2341:
2290:
2239:
2155:
2106:
1770:
1768:
1169:ghrelin/growth hormone secretagogue receptor
1156:Ghrelin/growth hormone secretagogue receptor
806:can sometimes be terminated with adenosine.
4467:Care of the Critically Ill Surgical Patient
4356:Australasian College for Emergency Medicine
3313:
3272:
3014:International Journal of Molecular Medicine
2507:(12th ed.). McGraw Hill. p. 245.
2252:International Journal of Molecular Sciences
1738:
195:In general: ā (Prescription only)
8506:Chemical substances for emergency medicine
7827:
7813:
5771:
5757:
5139:
5125:
4554:
4540:
4105:
4091:
3911:
3379:
3365:
1660:
1211:is not separated from the tunica media by
1012:
536:
513:
402:
45:
36:
8511:Drugs acting on the cardiovascular system
4028:
3337:
3296:
3212:
3160:Principles and Practice of Sleep Medicine
3102:
3025:
2940:
2930:
2881:
2828:
2805:
2756:
2746:
2697:
2640:
2591:
2581:
2422:
2373:
2324:
2314:
2273:
2263:
2187:
2138:
2113:Brown RA, Spina D, Page CP (March 2008).
1976:
1966:
1925:
1915:
1765:
1713:
1629:
1619:
1576:
1432:Cognitive behavioral therapy for insomnia
1366:
422:
7469:
4351:American College of Emergency Physicians
1171:. However, while it is able to increase
931:
4371:European Society for Emergency Medicine
2904:
2502:
1061:, and seizure activity. Activation of A
1004:, traditionally considered an absolute
509:
382:
8488:
8004:Tooltip Growth hormone-binding protein
7857:
7836:
4381:American Academy of Emergency Medicine
4112:
2831:Clinical and Experimental Rheumatology
2449:Smith RG, Betancourt L, Sun Y (2012).
1486:. These findings identify a potential
1467:by increasing adenosine levels in the
1277:is a known cause of immunodeficiency.
1182:
1076:
847:
730:adenosine mono-, di-, and triphosphate
527:
7808:
5752:
5120:
4535:
4086:
3386:
3360:
2621:Antimicrobial Agents and Chemotherapy
1696:Belhassen B, Pelleg A (August 1984).
1119:and decrease cAMP levels, while the A
939:'s principal mode of action is as an
482:
462:
86:
4376:Asian Society for Emergency Medicine
1526:List of growth hormone secretagogues
988:
943:of adenosine receptors in the brain.
921:
140:
4461:Advanced Life Support in Obstetrics
4366:Royal College of Emergency Medicine
1663:The New England Journal of Medicine
852:Adenosine is used as an adjunct to
827:monomorphic ventricular tachycardia
442:
333:
13:
6851:Tetramethylpyrazine (ligustrazine)
3172:10.1016/B978-1-4160-6645-3.00078-5
2874:10.1523/JNEUROSCI.22-15-06321.2002
1087:All adenosine receptor subtypes (A
910:, and/or chronic liver disease or
72:SR-96225 (developmental code name)
14:
8552:
3279:Costa F, Biaggioni I (May 1998).
3052:Acta Dermatovenerologica Croatica
2531:The Chinese Journal of Physiology
2505:Basic & Clinical Pharmacology
1949:Ribeiro JA, SebastiĆ£o AM (2010).
861:myocardial perfusion scintigraphy
4514:
4503:
4502:
4158:International emergency medicine
2979:10.1111/j.1346-8138.2008.00564.x
2633:10.1128/AAC.48.10.3944-3953.2004
2115:"Adenosine receptors and asthma"
1265:adenosine nucleoside transporter
1179:and increase its plasma levels.
567:
561:
4515:
4455:Pediatric Advanced Life Support
4168:Pre-hospital emergency medicine
3188:
3144:
3119:
3070:
3042:
2849:
2786:British Journal of Pharmacology
2657:
2608:
2549:
2521:
2496:
2471:
2390:
2204:
2119:British Journal of Pharmacology
2081:
2038:
2011:
1993:
1942:
1891:
1862:
1497:
1344:Adenosine is believed to be an
1123:adenosine receptors couple to G
773:
712:. Adenosine is one of the four
654:Key:OIRDTQYFTABQOQ-KQYNXXCUSA-N
7949:Somatrogon (MOD-4023; hGH-CTP)
6467:Tooltip Adenosine triphosphate
4443:Acute Care of at-Risk Newborns
4437:Neonatal Resuscitation Program
3625:Norepinephrine (noradrenaline)
2905:Lee FS, Chao MV (March 2001).
2415:10.1523/JNEUROSCI.3337-11.2011
2168:Nature Reviews. Drug Discovery
2047:Journal of Medicinal Chemistry
1955:Journal of Alzheimer's Disease
1826:
1808:Pijls NH, De Bruyne B (2000).
1801:
1689:
1654:
1595:
1570:
1537:
1275:Adenosine deaminase deficiency
800:AV nodal reentrant tachycardia
734:Cyclic adenosine monophosphate
573:
555:
1:
7795:Receptor/signaling modulators
6067:8-Phenyl-1,3-dipropylxanthine
4425:Advanced cardiac life support
4408:Cardiopulmonary resuscitation
3166:(1). Elsevier Inc.: 850ā865.
1715:10.1016/S0735-1097(84)80233-8
1531:
1226:
732:, also known as AMP/ADP/ATP.
629:n2c1c(ncnc1n(c2)3O((O)3O)CO)N
6052:3-Chlorostyrylcaffeine (CSC)
4449:Pediatric basic life support
4431:Advanced trauma life support
4414:Mouth-to-mouth resuscitation
4163:Pediatric emergency medicine
2748:10.1371/journal.pone.0002107
2366:10.1016/j.molmed.2013.03.005
2354:Trends in Molecular Medicine
2059:10.1021/acs.jmedchem.1c00261
1848:10.1016/0002-8703(92)90268-z
1521:Adenosine reuptake inhibitor
1450:delta-9-tetrahydrocannabinol
1340:Anti-inflammatory properties
873:supraventricular tachycardia
836:. When adenosine is used to
785:supraventricular tachycardia
779:Supraventricular tachycardia
7:
8496:Adenosine receptor agonists
7986:Antisense oligonucleotides:
3250:10.1152/ajpheart.00575.2004
2862:The Journal of Neuroscience
2403:The Journal of Neuroscience
1546:Bioorganometallic Chemistry
1509:
1280:
1205:inward rectifier K channels
1195:. This is mediated via the
1105:G-protein-coupled receptors
962:found in chocolate) have a
10:
8557:
7297:6-Hydroxy-7-methoxyflavone
5889:-ethylcarboxamidoadenosine
4784:(Nucleoside monophosphate)
4133:Emergency medical services
2967:The Journal of Dermatology
1621:10.1152/physrev.00049.2017
1579:Principles of Biochemistry
1577:Nelson DL, Cox MM (2005).
1289:
1285:
1193:atrioventricular (AV) node
1143:receptors also couple to G
1080:
766:) and as a radical in the
545:Chemical and physical data
20:
8516:Ghrelin receptor agonists
8457:
8254:
8174:
8012:
7855:
7788:
7629:
7579:
7467:
7450:
7423:
7345:
7282:
7265:
6876:
6455:
6440:
5837:
5806:
5789:
5709:
5668:
5631:
5588:
5556:
5486:
5469:
5432:
5349:
5295:
5242:
5183:
5159:
5067:
5024:
5015:
4978:
4940:
4933:
4886:
4838:
4790:
4779:
4727:
4656:
4647:
4639:Unnatural base pair (UBP)
4570:
4497:
4476:
4389:
4331:
4280:
4191:
4120:
3967:
3955:
3901:
3878:
3869:
3768:
3745:
3736:
3716:
3638:
3597:
3588:
3561:
3510:
3484:
3431:Glutamic acid (glutamate)
3426:Aspartic acid (aspartate)
3413:
3404:
3394:
3083:Journal of Sleep Research
1445:A principal component of
866:
662:
637:
617:
595:
582:
549:
544:
525:
493:
473:
453:
433:
413:
393:
373:
353:
328:
308:
268:
263:
253:
240:
230:
220:
210:
202:
186:
181:
171:
160:
152:
127:
115:
94:
76:
68:
58:
53:
44:
35:
7899:Human placental lactogen
7474:Tooltip Xanthine oxidase
4308:Epinephrine / Adrenaline
3615:Epinephrine (adrenaline)
3339:10.1161/01.CIR.84.3.1145
3298:10.1161/01.HYP.31.5.1061
2485:(in Russian). 2021-03-18
2225:10.1016/j.it.2003.11.003
1951:"Caffeine and adenosine"
1417:
896:congestive heart failure
796:AV reentrant tachycardia
21:Not to be confused with
8541:Hydroxymethyl compounds
7064:UDP-N-acetylglucosamine
5017:Nucleoside triphosphate
2837:(5 Suppl 61): S21āS23.
2583:10.1073/pnas.0907010106
1401:
1244:adenosine monophosphate
1013:Pharmacological effects
736:(cAMP) is pervasive in
724:is a building block of
8291:Examorelin (hexarelin)
7508:Cinnamomum osmophloeum
6132:Choline theophyllinate
4970:Xanthosine diphosphate
4934:Nucleoside diphosphate
4050:Carbonyl sulfide (COS)
3651:N-Methylphenethylamine
3214:10.1093/sleep/26.8.943
2932:10.1073/pnas.061020198
2125:(Suppl 1): S446āS456.
1836:American Heart Journal
1438:, utilizes short-term
1373:central nervous system
1367:Central nervous system
1328:is protective against
1253:, which is present in
1213:atherosclerotic plaque
997:for adenosine include
944:
912:chronic kidney disease
802:(AVNRT). In addition,
792:re-entrant arrhythmias
8501:Antiarrhythmic agents
6751:Opiranserin (VVZ-149)
5987:-Cyclopentyladenosine
5601:muscarinic antagonist
5148:Antiarrhythmic agents
4489:Injury Severity Score
4260:Nasopharyngeal airway
4233:Intraosseous infusion
3791:2-AGE (noladin ether)
3127:"Adenosine and Sleep"
3027:10.3892/ijmm.2011.817
1968:10.3233/JAD-2010-1379
1904:Pulmonary Circulation
1608:Physiological Reviews
1412:androgenetic alopecia
1296:The adenosine analog
1257:and the vessel wall.
1235:can be the result of
1131:receptors couple to G
1115:receptors couple to G
935:
900:myocardial infarction
8346:Pralmorelin (GHRP-2)
7889:Eftansomatropin alfa
7550:Pistacia integerrima
6856:Ligusticum wallichii
6834:Ligusticum wallichii
6072:8-Phenyltheophylline
6062:8-Chlorotheophylline
6002:Neladenoson dalanate
4266:Oropharyngeal airway
4143:Emergency psychiatry
4128:Emergency department
4002:Carbon monoxide (CO)
3153:"Models of insomnia"
2798:10.1038/bjp.2008.329
2316:10.3390/cells9010052
2265:10.3390/ijms19123837
2213:Trends in Immunology
1917:10.1192/apt.11.6.432
1777:"Reentry Arrhythmia"
1675:10.1056/NEJMcp051145
1231:Adenosine used as a
834:antiarrhythmic agent
783:In individuals with
720:(and its derivative
8388:Ibutamoren (MK-677)
8216:Modified GRF (1-29)
8116:Somatostatin (1-28)
8111:Somatostatin (GHIH)
7879:Bovine somatotropin
5443:Ca channel blockers
5175:Na channel blockers
4840:Deoxyribonucleotide
4729:Deoxyribonucleoside
4632:Pyrimidine analogue
4245:Tracheal intubation
4239:Intravenous therapy
4007:Hydrogen sulfide (H
3861:Virodhamine (O-AEA)
2923:2001PNAS...98.3555L
2739:2008PLoSO...3.2107N
2690:10.1038/nature13027
2682:2014Natur.508..402W
2574:2009PNAS..10620435Y
2568:(48): 20435ā20439.
2409:(37): 13272ā13280.
2131:10.1038/bjp.2008.22
1292:Nucleoside analogue
1251:adenosine deaminase
1240:purine biosynthesis
1183:Mechanism of action
1077:Adenosine receptors
877:parenteral infusion
848:Nuclear stress test
815:atrial fibrillation
762:(an active form of
742:cardiac arrhythmias
738:signal transduction
716:building blocks of
32:
5736:Never to phase III
5619:muscarinic agonist
5360:K channel blockers
4419:Basic life support
4323:Sodium bicarbonate
4121:Emergency medicine
4114:Emergency medicine
4064:Sulfur dioxide (SO
3975:Cholinergic system
3677:Phenylethanolamine
3656:N-Methyltryptamine
3620:NAS (normelatonin)
3407:inhibitory systems
3405:Major excitatory /
3244:(4): H1633āH1640.
2503:Katzung B (2012).
2090:Principles of Life
1961:(Suppl 1): S3-15.
1516:Adenosine receptor
1263:, an inhibitor of
1083:Adenosine receptor
945:
858:technetium (Tc99m)
804:atrial tachycardia
28:
8531:Neurotransmitters
8483:
8482:
8465:
8438:
8262:
8182:
8156:Cyclosomatostatin
8020:
7996:Binding proteins:
7904:Lonapegsomatropin
7863:
7802:
7801:
7625:
7624:
7602:Mycophenolic acid
7461:
7446:
7445:
7276:
7261:
7260:
7257:
7256:
6828:Angelica sinensis
5870:2-Chloroadenosine
5800:
5746:
5745:
5705:
5704:
5664:
5663:
5465:
5464:
5345:
5344:
5114:
5113:
5110:
5109:
5011:
5010:
4929:
4928:
4888:Cyclic nucleotide
4775:
4774:
4529:
4528:
4318:Magnesium sulfate
4227:Electrocardiogram
4153:Medical emergency
4138:Emergency nursing
4080:
4079:
4076:
4075:
4024:
4023:
4016:Nitric oxide (NO)
3990:
3989:
3963:
3951:
3950:
3947:
3946:
3897:
3896:
3893:
3892:
3764:
3763:
3760:
3759:
3732:
3731:
3646:3-Iodothyronamine
3584:
3583:
3388:Neurotransmitters
3095:10.1111/jsr.13597
2868:(15): 6321ā6324.
2676:(7496): 402ā405.
2627:(10): 3944ā3953.
2514:978-0-07-176402-5
2464:978-3-642-18999-9
2099:978-1-4641-8652-3
2053:(11): 7156ā7178.
1870:"2014 Guidelines"
1810:Coronary Pressure
1753:(6): 572ā3, 581.
1669:(10): 1039ā1051.
1440:sleep deprivation
1381:neurotransmitters
1354:diabetes mellitus
1346:anti-inflammatory
1322:hepatitis C virus
1109:adenylate cyclase
1071:immunosuppressive
995:contraindications
989:Contraindications
958:found in tea, or
954:found in coffee,
922:Drug interactions
890:(Persantine) and
881:antecubital fossa
760:adenosylcobalamin
680:
679:
608:Interactive image
495:CompTox Dashboard
16:Chemical compound
8548:
8463:
8461:
8436:
8260:
8258:
8180:
8178:
8018:
8016:
8005:
8001:
7934:Somatropin pegol
7861:
7859:
7842:
7838:
7829:
7822:
7815:
7806:
7805:
7475:
7471:
7465:
7464:
7455:
7431:
7427:
7353:
7349:
7290:
7286:
7280:
7279:
7270:
6664:Rheum officinale
6468:
6464:
6453:
6452:
6112:Caffeine citrate
6057:7-Methylxanthine
5860:-methyladenosine
5804:
5803:
5794:
5773:
5766:
5759:
5750:
5749:
5675:
5674:
5670:Ion transporters
5484:
5483:
5181:
5180:
5166:
5165:
5161:Channel blockers
5141:
5134:
5127:
5118:
5117:
5022:
5021:
4938:
4937:
4788:
4787:
4709:-Methyladenosine
4686:5-Methylcytidine
4654:
4653:
4556:
4549:
4542:
4533:
4532:
4518:
4517:
4506:
4505:
4107:
4100:
4093:
4084:
4083:
4055:Nitrous oxide (N
4026:
4025:
3995:Gasotransmitters
3992:
3991:
3972:
3971:
3962:
3916:
3915:
3909:
3908:
3876:
3875:
3811:Anandamide (AEA)
3779:Endocannabinoids
3776:
3775:
3743:
3742:
3630:Serotonin (5-HT)
3595:
3594:
3414:Glutamate system
3411:
3410:
3402:
3401:
3381:
3374:
3367:
3358:
3357:
3352:
3351:
3341:
3332:(3): 1145ā1149.
3317:
3311:
3310:
3300:
3291:(5): 1061ā1064.
3276:
3270:
3269:
3233:
3227:
3226:
3216:
3192:
3186:
3185:
3157:
3148:
3142:
3141:
3139:
3138:
3131:Sleep Foundation
3123:
3117:
3116:
3106:
3074:
3068:
3067:
3046:
3040:
3039:
3029:
3005:
2999:
2998:
2961:
2955:
2954:
2944:
2934:
2917:(6): 3555ā3560.
2902:
2896:
2895:
2885:
2853:
2847:
2846:
2826:
2820:
2819:
2809:
2777:
2771:
2770:
2760:
2750:
2718:
2712:
2711:
2701:
2661:
2655:
2654:
2644:
2612:
2606:
2605:
2595:
2585:
2553:
2547:
2546:
2525:
2519:
2518:
2500:
2494:
2493:
2491:
2490:
2475:
2469:
2468:
2446:
2437:
2436:
2426:
2394:
2388:
2387:
2377:
2345:
2339:
2338:
2328:
2318:
2294:
2288:
2287:
2277:
2267:
2243:
2237:
2236:
2208:
2202:
2201:
2191:
2159:
2153:
2152:
2142:
2110:
2104:
2103:
2085:
2079:
2078:
2042:
2036:
2035:
2015:
2009:
2008:
1997:
1991:
1990:
1980:
1970:
1946:
1940:
1939:
1929:
1919:
1895:
1889:
1888:
1886:
1884:
1874:
1866:
1860:
1859:
1830:
1824:
1823:
1805:
1799:
1798:
1796:
1795:
1772:
1763:
1762:
1742:
1736:
1735:
1717:
1693:
1687:
1686:
1658:
1652:
1651:
1633:
1623:
1614:(3): 1591ā1625.
1599:
1593:
1592:
1574:
1568:
1567:
1554:10.1007/3418_004
1541:
1424:sleep-wake cycle
1233:second messenger
1160:Adenosine is an
1006:contraindication
694:organic compound
676:
675:
668:
610:
590:
575:
569:
563:
557:
540:
529:
518:
517:
503:
501:
486:
466:
446:
426:
406:
386:
366:
346:
336:
335:
321:
245:
144:
90:
49:
40:
33:
31:
27:
8556:
8555:
8551:
8550:
8549:
8547:
8546:
8545:
8486:
8485:
8484:
8479:
8462:
8453:
8259:
8250:
8179:
8170:
8017:
8008:
8003:
7884:Efpegsomatropin
7860:
7851:
7833:
7803:
7798:
7784:
7621:
7575:
7473:
7454:
7442:
7429:
7419:
7415:Propentofylline
7365:Benzodiazepines
7351:
7341:
7288:
7269:
7253:
6872:
6823:Sodium ferulate
6791:Radix puerariae
6766:Phenolphthalein
6466:
6459:
6444:
6436:
6317:Propentofylline
6217:Isovaleric acid
5841:
5833:
5793:
5785:
5780:Purine receptor
5777:
5747:
5742:
5741:
5726:Clinical trials
5701:
5660:
5627:
5617:
5593:
5584:
5575:Benzodiazepines
5561:
5552:
5521:cardioselective
5490:
5476:
5461:
5436:
5428:
5353:
5341:
5291:
5238:
5172:
5155:
5145:
5115:
5106:
5063:
5007:
4974:
4925:
4882:
4834:
4783:
4771:
4767:Deoxyxanthosine
4723:
4676:5-Methyluridine
4643:
4605:Purine analogue
4566:
4560:
4530:
4525:
4493:
4477:Scoring systems
4472:
4385:
4327:
4276:
4187:
4116:
4111:
4081:
4072:
4067:
4058:
4044:
4020:
4010:
3986:
3943:
3889:
3865:
3756:
3728:
3712:
3634:
3590:Biogenic amines
3580:
3557:
3506:
3480:
3406:
3390:
3385:
3355:
3318:
3314:
3277:
3273:
3234:
3230:
3193:
3189:
3182:
3155:
3149:
3145:
3136:
3134:
3125:
3124:
3120:
3075:
3071:
3047:
3043:
3006:
3002:
2973:(12): 763ā767.
2962:
2958:
2903:
2899:
2854:
2850:
2827:
2823:
2778:
2774:
2719:
2715:
2662:
2658:
2613:
2609:
2554:
2550:
2526:
2522:
2515:
2501:
2497:
2488:
2486:
2477:
2476:
2472:
2465:
2447:
2440:
2395:
2391:
2346:
2342:
2295:
2291:
2244:
2240:
2209:
2205:
2180:10.1038/nrd2638
2160:
2156:
2111:
2107:
2100:
2086:
2082:
2043:
2039:
2016:
2012:
1999:
1998:
1994:
1947:
1943:
1896:
1892:
1882:
1880:
1872:
1868:
1867:
1863:
1831:
1827:
1820:
1806:
1802:
1793:
1791:
1773:
1766:
1743:
1739:
1694:
1690:
1659:
1655:
1600:
1596:
1589:
1575:
1571:
1564:
1542:
1538:
1534:
1512:
1500:
1488:therapeutic use
1473:slow-wave sleep
1469:basal forebrain
1454:endocannabinoid
1420:
1404:
1397:
1369:
1351:
1342:
1294:
1288:
1283:
1255:red blood cells
1229:
1200:
1185:
1158:
1146:
1142:
1138:
1134:
1130:
1126:
1122:
1118:
1114:
1111:activity. The A
1102:
1098:
1094:
1090:
1085:
1079:
1064:
1043:
1036:
1029:
1022:
1015:
991:
978:
948:Methylxanthines
924:
869:
850:
781:
776:
710:glycosidic bond
707:
671:
669:
666:(what is this?)
663:
658:
655:
650:
645:
644:
633:
630:
625:
624:
613:
588:
578:
572:
566:
560:
521:
497:
489:
469:
449:
429:
409:
389:
369:
349:
332:
324:
304:
301:
276:
275:
243:
222:Protein binding
212:Bioavailability
204:Pharmacokinetic
198:
167:Primarily liver
148:
118:
111:
97:
26:
17:
12:
11:
5:
8554:
8544:
8543:
8538:
8533:
8528:
8523:
8518:
8513:
8508:
8503:
8498:
8481:
8480:
8478:
8477:
8469:
8467:
8455:
8454:
8452:
8451:
8446:
8441:
8432:
8427:
8418:
8417:
8412:
8400:
8395:
8390:
8385:
8380:
8375:
8370:
8358:
8353:
8348:
8343:
8338:
8333:
8328:
8323:
8318:
8313:
8308:
8303:
8298:
8293:
8288:
8283:
8281:Cortistatin-14
8278:
8266:
8264:
8252:
8251:
8249:
8248:
8239:
8238:
8233:
8228:
8223:
8218:
8213:
8208:
8203:
8198:
8186:
8184:
8181:(somatocrinin)
8172:
8171:
8169:
8168:
8163:
8158:
8153:
8144:
8143:
8138:
8133:
8128:
8123:
8118:
8113:
8108:
8103:
8098:
8093:
8088:
8083:
8078:
8073:
8068:
8063:
8058:
8053:
8048:
8043:
8041:Cortistatin-14
8038:
8033:
8024:
8022:
8019:(somatostatin)
8010:
8009:
8007:
8006:
7992:
7991:
7982:
7981:
7976:
7967:
7966:
7961:
7956:
7951:
7946:
7941:
7936:
7931:
7926:
7921:
7916:
7911:
7906:
7901:
7896:
7894:Growth hormone
7891:
7886:
7881:
7876:
7874:Albusomatropin
7867:
7865:
7862:(somatotropin)
7853:
7852:
7832:
7831:
7824:
7817:
7809:
7800:
7799:
7789:
7786:
7785:
7783:
7782:
7768:
7767:
7762:
7757:
7752:
7747:
7742:
7737:
7732:
7727:
7722:
7717:
7712:
7707:
7702:
7697:
7692:
7687:
7682:
7677:
7672:
7667:
7662:
7657:
7652:
7647:
7642:
7633:
7631:
7627:
7626:
7623:
7622:
7620:
7619:
7614:
7609:
7604:
7599:
7594:
7589:
7583:
7581:
7577:
7576:
7574:
7573:
7568:
7563:
7558:
7553:
7546:
7541:
7536:
7531:
7526:
7521:
7516:
7511:
7504:
7502:Cinnamaldehyde
7499:
7494:
7489:
7484:
7478:
7476:
7462:
7448:
7447:
7444:
7443:
7441:
7440:
7434:
7432:
7421:
7420:
7418:
7417:
7412:
7407:
7405:Pentoxifylline
7402:
7397:
7392:
7387:
7382:
7377:
7372:
7367:
7362:
7356:
7354:
7343:
7342:
7340:
7339:
7334:
7329:
7324:
7319:
7314:
7309:
7304:
7299:
7293:
7291:
7277:
7263:
7262:
7259:
7258:
7255:
7254:
7252:
7251:
7246:
7241:
7236:
7231:
7226:
7221:
7216:
7211:
7206:
7201:
7196:
7191:
7186:
7181:
7176:
7171:
7166:
7161:
7156:
7151:
7146:
7141:
7136:
7131:
7126:
7121:
7116:
7111:
7106:
7101:
7096:
7091:
7082:
7081:
7076:
7071:
7066:
7061:
7056:
7051:
7046:
7041:
7036:
7031:
7026:
7021:
7016:
7011:
7006:
7001:
6996:
6991:
6986:
6981:
6976:
6971:
6966:
6961:
6956:
6951:
6946:
6941:
6936:
6931:
6926:
6921:
6916:
6911:
6906:
6901:
6896:
6891:
6882:
6880:
6874:
6873:
6871:
6870:
6865:
6860:
6848:
6843:
6838:
6820:
6815:
6810:
6805:
6800:
6795:
6783:
6778:
6773:
6768:
6763:
6758:
6753:
6748:
6743:
6738:
6733:
6728:
6723:
6718:
6713:
6708:
6703:
6698:
6693:
6688:
6683:
6678:
6673:
6668:
6656:
6651:
6646:
6641:
6636:
6631:
6626:
6621:
6616:
6611:
6606:
6601:
6596:
6591:
6582:
6581:
6576:
6571:
6566:
6561:
6556:
6551:
6546:
6541:
6536:
6531:
6526:
6521:
6516:
6511:
6506:
6501:
6496:
6491:
6486:
6481:
6472:
6470:
6450:
6438:
6437:
6435:
6434:
6429:
6424:
6419:
6414:
6409:
6404:
6399:
6394:
6389:
6384:
6379:
6374:
6369:
6364:
6359:
6354:
6349:
6344:
6339:
6334:
6329:
6324:
6319:
6314:
6309:
6307:Pentoxifylline
6304:
6299:
6294:
6289:
6284:
6279:
6274:
6269:
6264:
6259:
6254:
6249:
6244:
6239:
6234:
6229:
6224:
6222:Istradefylline
6219:
6214:
6209:
6204:
6199:
6194:
6189:
6184:
6179:
6174:
6169:
6164:
6159:
6154:
6149:
6144:
6139:
6134:
6129:
6124:
6119:
6114:
6109:
6104:
6099:
6094:
6089:
6084:
6079:
6074:
6069:
6064:
6059:
6054:
6045:
6044:
6039:
6034:
6029:
6024:
6019:
6014:
6009:
6004:
5999:
5994:
5989:
5981:
5976:
5971:
5966:
5961:
5956:
5951:
5946:
5941:
5936:
5931:
5926:
5921:
5916:
5911:
5906:
5901:
5896:
5891:
5882:
5877:
5872:
5867:
5862:
5856:2-(1-Hexynyl)-
5849:
5847:
5835:
5834:
5832:
5831:
5826:
5824:8-Aminoadenine
5817:
5815:
5801:
5787:
5786:
5776:
5775:
5768:
5761:
5753:
5744:
5743:
5740:
5739:
5738:
5737:
5734:
5723:
5717:
5711:
5710:
5707:
5706:
5703:
5702:
5700:
5699:
5694:
5689:
5683:
5681:
5672:
5666:
5665:
5662:
5661:
5659:
5658:
5653:
5648:
5643:
5637:
5635:
5629:
5628:
5626:
5625:
5612:
5607:
5597:
5595:
5591:
5586:
5585:
5583:
5582:
5577:
5572:
5566:
5564:
5559:
5554:
5553:
5551:
5550:
5549:
5548:
5543:
5538:
5533:
5528:
5518:
5513:
5508:
5502:
5500:
5481:
5467:
5466:
5463:
5462:
5460:
5459:
5454:
5448:
5446:
5430:
5429:
5427:
5426:
5421:
5416:
5411:
5406:
5401:
5396:
5391:
5386:
5381:
5376:
5371:
5365:
5363:
5347:
5346:
5343:
5342:
5340:
5339:
5334:
5329:
5324:
5319:
5314:
5309:
5303:
5301:
5293:
5292:
5290:
5289:
5288:
5287:
5282:
5277:
5265:
5264:
5263:
5250:
5248:
5240:
5239:
5237:
5236:
5231:
5226:
5221:
5216:
5211:
5209:Hydroquinidine
5206:
5201:
5195:
5193:
5178:
5163:
5157:
5156:
5144:
5143:
5136:
5129:
5121:
5112:
5111:
5108:
5107:
5105:
5104:
5099:
5094:
5089:
5084:
5079:
5074:
5068:
5065:
5064:
5062:
5061:
5056:
5051:
5046:
5041:
5036:
5031:
5025:
5019:
5013:
5012:
5009:
5008:
5006:
5005:
5000:
4995:
4990:
4985:
4979:
4976:
4975:
4973:
4972:
4967:
4962:
4957:
4952:
4947:
4941:
4935:
4931:
4930:
4927:
4926:
4924:
4923:
4918:
4913:
4908:
4903:
4898:
4892:
4890:
4884:
4883:
4881:
4880:
4875:
4870:
4865:
4860:
4855:
4850:
4844:
4842:
4836:
4835:
4833:
4832:
4827:
4822:
4817:
4812:
4807:
4802:
4796:
4794:
4792:Ribonucleotide
4785:
4777:
4776:
4773:
4772:
4770:
4769:
4764:
4759:
4754:
4749:
4744:
4742:Deoxyguanosine
4739:
4737:Deoxyadenosine
4733:
4731:
4725:
4724:
4722:
4721:
4716:
4711:
4703:
4698:
4693:
4688:
4683:
4678:
4673:
4668:
4662:
4660:
4658:Ribonucleoside
4651:
4645:
4644:
4642:
4641:
4636:
4635:
4634:
4629:
4624:
4619:
4609:
4608:
4607:
4602:
4597:
4592:
4587:
4576:
4574:
4568:
4567:
4559:
4558:
4551:
4544:
4536:
4527:
4526:
4524:
4523:
4511:
4498:
4495:
4494:
4492:
4491:
4486:
4480:
4478:
4474:
4473:
4471:
4470:
4464:
4458:
4452:
4446:
4440:
4434:
4428:
4422:
4416:
4411:
4405:
4399:
4397:
4387:
4386:
4384:
4383:
4378:
4373:
4368:
4363:
4358:
4353:
4348:
4337:
4335:
4329:
4328:
4326:
4325:
4320:
4315:
4310:
4305:
4300:
4295:
4290:
4284:
4282:
4278:
4277:
4275:
4274:
4269:
4263:
4257:
4252:
4250:Laryngeal tube
4247:
4242:
4236:
4230:
4224:
4218:
4212:Defibrillation
4209:
4204:
4201:Bag valve mask
4197:
4195:
4189:
4188:
4186:
4185:
4180:
4175:
4170:
4165:
4160:
4155:
4150:
4145:
4140:
4135:
4130:
4124:
4122:
4118:
4117:
4110:
4109:
4102:
4095:
4087:
4078:
4077:
4074:
4073:
4071:
4070:
4065:
4061:
4056:
4052:
4047:
4042:
4038:
4032:
4030:
4022:
4021:
4019:
4018:
4013:
4008:
4004:
3998:
3996:
3988:
3987:
3985:
3984:
3978:
3976:
3969:
3965:
3964:
3960:
3953:
3952:
3949:
3948:
3945:
3944:
3942:
3941:
3936:
3931:
3925:
3923:
3913:
3906:
3899:
3898:
3895:
3894:
3891:
3890:
3888:
3887:
3879:
3873:
3867:
3866:
3864:
3863:
3858:
3853:
3848:
3843:
3838:
3833:
3828:
3823:
3818:
3813:
3808:
3803:
3798:
3793:
3788:
3782:
3780:
3773:
3766:
3765:
3762:
3761:
3758:
3757:
3755:
3754:
3746:
3740:
3734:
3733:
3730:
3729:
3727:
3726:
3720:
3718:
3714:
3713:
3711:
3710:
3702:
3694:
3689:
3684:
3682:Phenethylamine
3679:
3674:
3666:
3658:
3653:
3648:
3642:
3640:
3636:
3635:
3633:
3632:
3627:
3622:
3617:
3612:
3607:
3601:
3599:
3592:
3586:
3585:
3582:
3581:
3579:
3578:
3573:
3567:
3565:
3559:
3558:
3556:
3555:
3550:
3545:
3540:
3535:
3530:
3525:
3520:
3514:
3512:
3511:Glycine system
3508:
3507:
3505:
3504:
3499:
3494:
3488:
3486:
3482:
3481:
3479:
3478:
3473:
3468:
3463:
3458:
3456:Kynurenic acid
3453:
3448:
3443:
3438:
3433:
3428:
3423:
3417:
3415:
3408:
3399:
3392:
3391:
3384:
3383:
3376:
3369:
3361:
3354:
3353:
3312:
3271:
3228:
3207:(8): 943ā947.
3187:
3180:
3143:
3118:
3069:
3058:(3): 155ā159.
3041:
3020:(2): 195ā201.
3000:
2956:
2897:
2848:
2821:
2792:(4): 463ā474.
2772:
2713:
2656:
2607:
2548:
2537:(4): 245ā252.
2520:
2513:
2495:
2470:
2463:
2438:
2389:
2360:(6): 355ā367.
2340:
2289:
2238:
2203:
2174:(9): 759ā770.
2154:
2105:
2098:
2080:
2037:
2026:(2): 637ā642.
2010:
2007:on 2011-07-15.
1992:
1941:
1910:(1): 432ā439.
1890:
1877:regionsems.com
1861:
1842:(3): 614ā621.
1825:
1818:
1800:
1764:
1737:
1708:(2): 414ā424.
1688:
1653:
1594:
1587:
1569:
1562:
1535:
1533:
1530:
1529:
1528:
1523:
1518:
1511:
1508:
1499:
1496:
1479:, mediated by
1459:(AEA) induces
1452:(THC) and the
1419:
1416:
1403:
1400:
1395:
1368:
1365:
1349:
1348:agent at the A
1341:
1338:
1302:RNA polymerase
1287:
1284:
1282:
1279:
1269:vasodilatation
1228:
1225:
1221:coronary steal
1198:
1184:
1181:
1177:growth hormone
1157:
1154:
1147:and stimulate
1144:
1140:
1136:
1132:
1128:
1124:
1120:
1116:
1112:
1100:
1096:
1092:
1088:
1081:Main article:
1078:
1075:
1062:
1041:
1034:
1027:
1020:
1014:
1011:
1010:
1009:
990:
987:
976:
923:
920:
868:
865:
849:
846:
819:atrial flutter
780:
777:
775:
772:
722:deoxyadenosine
705:
700:attached to a
678:
677:
660:
659:
657:
656:
653:
651:
648:
640:
639:
638:
635:
634:
632:
631:
628:
620:
619:
618:
615:
614:
612:
611:
603:
601:
593:
592:
586:
580:
579:
576:
570:
564:
558:
553:
547:
546:
542:
541:
531:
523:
522:
520:
519:
506:
504:
491:
490:
488:
487:
479:
477:
471:
470:
468:
467:
459:
457:
451:
450:
448:
447:
439:
437:
431:
430:
428:
427:
419:
417:
411:
410:
408:
407:
399:
397:
391:
390:
388:
387:
379:
377:
371:
370:
368:
367:
359:
357:
351:
350:
348:
347:
339:
337:
326:
325:
323:
322:
314:
312:
306:
305:
303:
302:
296:)-2-(6-amino-9
279:
271:
270:
269:
266:
265:
261:
260:
257:
251:
250:
247:
238:
237:
234:
228:
227:
224:
218:
217:
214:
208:
207:
200:
199:
197:
196:
192:
190:
184:
183:
179:
178:
175:
169:
168:
165:
158:
157:
150:
149:
147:
146:
133:
131:
125:
124:
121:
119:administration
113:
112:
107:
106:
102:
100:
92:
91:
84:
74:
73:
70:
66:
65:
62:
56:
55:
51:
50:
42:
41:
15:
9:
6:
4:
3:
2:
8553:
8542:
8539:
8537:
8534:
8532:
8529:
8527:
8524:
8522:
8519:
8517:
8514:
8512:
8509:
8507:
8504:
8502:
8499:
8497:
8494:
8493:
8491:
8475:
8471:
8470:
8468:
8466:
8464:(somatomedin)
8456:
8450:
8447:
8445:
8442:
8440:
8439:-LysĀ³)-GHRP-6
8433:
8431:
8430:Cortistatin-8
8428:
8426:
8423:
8420:
8419:
8416:
8413:
8411:
8408:
8404:
8401:
8399:
8396:
8394:
8391:
8389:
8386:
8384:
8381:
8379:
8376:
8374:
8371:
8369:
8366:
8362:
8359:
8357:
8354:
8352:
8349:
8347:
8344:
8342:
8339:
8337:
8334:
8332:
8329:
8327:
8324:
8322:
8319:
8317:
8314:
8312:
8309:
8307:
8304:
8302:
8299:
8297:
8294:
8292:
8289:
8287:
8284:
8282:
8279:
8277:
8274:
8271:
8268:
8267:
8265:
8263:
8253:
8247:
8244:
8241:
8240:
8237:
8234:
8232:
8229:
8227:
8224:
8222:
8219:
8217:
8214:
8212:
8209:
8207:
8204:
8202:
8199:
8197:
8194:
8191:
8188:
8187:
8185:
8183:
8173:
8167:
8164:
8162:
8159:
8157:
8154:
8152:
8149:
8146:
8145:
8142:
8139:
8137:
8134:
8132:
8129:
8127:
8124:
8122:
8119:
8117:
8114:
8112:
8109:
8107:
8104:
8102:
8099:
8097:
8096:Pentetreotide
8094:
8092:
8089:
8087:
8084:
8082:
8079:
8077:
8074:
8072:
8069:
8067:
8064:
8062:
8059:
8057:
8054:
8052:
8049:
8047:
8044:
8042:
8039:
8037:
8034:
8032:
8029:
8026:
8025:
8023:
8021:
8011:
8002:
7997:
7994:
7993:
7990:
7987:
7984:
7983:
7980:
7977:
7975:
7972:
7969:
7968:
7965:
7962:
7960:
7957:
7955:
7952:
7950:
7947:
7945:
7942:
7940:
7937:
7935:
7932:
7930:
7927:
7925:
7922:
7920:
7917:
7915:
7912:
7910:
7907:
7905:
7902:
7900:
7897:
7895:
7892:
7890:
7887:
7885:
7882:
7880:
7877:
7875:
7872:
7869:
7868:
7866:
7864:
7854:
7850:
7847:
7844:
7830:
7825:
7823:
7818:
7816:
7811:
7810:
7807:
7797:
7796:
7793:
7787:
7780:
7776:
7773:
7770:
7769:
7766:
7763:
7761:
7758:
7756:
7753:
7751:
7748:
7746:
7743:
7741:
7738:
7736:
7733:
7731:
7728:
7726:
7723:
7721:
7718:
7716:
7713:
7711:
7708:
7706:
7703:
7701:
7698:
7696:
7693:
7691:
7688:
7686:
7683:
7681:
7678:
7676:
7673:
7671:
7668:
7666:
7663:
7661:
7658:
7656:
7653:
7651:
7648:
7646:
7643:
7641:
7638:
7635:
7634:
7632:
7628:
7618:
7615:
7613:
7610:
7608:
7605:
7603:
7600:
7598:
7595:
7593:
7590:
7588:
7585:
7584:
7582:
7578:
7572:
7569:
7567:
7564:
7562:
7559:
7557:
7554:
7552:
7551:
7547:
7545:
7542:
7540:
7537:
7535:
7532:
7530:
7527:
7525:
7522:
7520:
7517:
7515:
7512:
7510:
7509:
7505:
7503:
7500:
7498:
7495:
7493:
7492:Benzbromarone
7490:
7488:
7485:
7483:
7480:
7479:
7477:
7472:
7466:
7463:
7459:
7453:
7449:
7439:
7436:
7435:
7433:
7428:
7422:
7416:
7413:
7411:
7408:
7406:
7403:
7401:
7398:
7396:
7393:
7391:
7388:
7386:
7383:
7381:
7378:
7376:
7373:
7371:
7368:
7366:
7363:
7361:
7358:
7357:
7355:
7350:
7344:
7338:
7335:
7333:
7330:
7328:
7325:
7323:
7320:
7318:
7315:
7313:
7310:
7308:
7305:
7303:
7300:
7298:
7295:
7294:
7292:
7287:
7281:
7278:
7274:
7268:
7264:
7250:
7247:
7245:
7242:
7240:
7237:
7235:
7232:
7230:
7227:
7225:
7222:
7220:
7217:
7215:
7212:
7210:
7207:
7205:
7202:
7200:
7197:
7195:
7192:
7190:
7187:
7185:
7182:
7180:
7177:
7175:
7172:
7170:
7167:
7165:
7162:
7160:
7157:
7155:
7152:
7150:
7147:
7145:
7142:
7140:
7137:
7135:
7132:
7130:
7127:
7125:
7124:AR-C 118925XX
7122:
7120:
7117:
7115:
7112:
7110:
7107:
7105:
7102:
7100:
7097:
7095:
7092:
7090:
7087:
7084:
7083:
7080:
7077:
7075:
7072:
7070:
7067:
7065:
7062:
7060:
7057:
7055:
7054:UDP-galactose
7052:
7050:
7047:
7045:
7042:
7040:
7037:
7035:
7032:
7030:
7027:
7025:
7022:
7020:
7017:
7015:
7012:
7010:
7007:
7005:
7002:
7000:
6997:
6995:
6992:
6990:
6987:
6985:
6982:
6980:
6977:
6975:
6972:
6970:
6967:
6965:
6962:
6960:
6957:
6955:
6952:
6950:
6947:
6945:
6942:
6940:
6937:
6935:
6932:
6930:
6927:
6925:
6922:
6920:
6917:
6915:
6912:
6910:
6907:
6905:
6902:
6900:
6897:
6895:
6892:
6890:
6887:
6884:
6883:
6881:
6879:
6875:
6869:
6866:
6864:
6861:
6858:
6857:
6852:
6849:
6847:
6844:
6842:
6839:
6836:
6835:
6830:
6829:
6824:
6821:
6819:
6816:
6814:
6811:
6809:
6806:
6804:
6801:
6799:
6796:
6793:
6792:
6787:
6784:
6782:
6779:
6777:
6774:
6772:
6769:
6767:
6764:
6762:
6759:
6757:
6754:
6752:
6749:
6747:
6744:
6742:
6739:
6737:
6734:
6732:
6729:
6727:
6724:
6722:
6719:
6717:
6714:
6712:
6709:
6707:
6704:
6702:
6699:
6697:
6694:
6692:
6689:
6687:
6684:
6682:
6679:
6677:
6674:
6672:
6669:
6666:
6665:
6660:
6657:
6655:
6652:
6650:
6649:Chelerythrine
6647:
6645:
6644:Calmidazolium
6642:
6640:
6637:
6635:
6632:
6630:
6627:
6625:
6622:
6620:
6617:
6615:
6612:
6610:
6607:
6605:
6602:
6600:
6597:
6595:
6592:
6590:
6587:
6584:
6583:
6580:
6577:
6575:
6572:
6570:
6567:
6565:
6562:
6560:
6557:
6555:
6552:
6550:
6547:
6545:
6542:
6540:
6537:
6535:
6532:
6530:
6529:Cibacron blue
6527:
6525:
6522:
6520:
6517:
6515:
6512:
6510:
6507:
6505:
6502:
6500:
6497:
6495:
6492:
6490:
6487:
6485:
6482:
6480:
6477:
6474:
6473:
6471:
6465:
6458:
6454:
6451:
6448:
6443:
6439:
6433:
6430:
6428:
6425:
6423:
6420:
6418:
6415:
6413:
6410:
6408:
6405:
6403:
6402:Theodrenaline
6400:
6398:
6395:
6393:
6390:
6388:
6385:
6383:
6382:Sipagladenant
6380:
6378:
6375:
6373:
6370:
6368:
6365:
6363:
6360:
6358:
6355:
6353:
6350:
6348:
6345:
6343:
6340:
6338:
6335:
6333:
6330:
6328:
6325:
6323:
6322:Proxyphylline
6320:
6318:
6315:
6313:
6310:
6308:
6305:
6303:
6300:
6298:
6295:
6293:
6290:
6288:
6285:
6283:
6280:
6278:
6275:
6273:
6270:
6268:
6265:
6263:
6260:
6258:
6255:
6253:
6250:
6248:
6245:
6243:
6240:
6238:
6235:
6233:
6230:
6228:
6225:
6223:
6220:
6218:
6215:
6213:
6210:
6208:
6205:
6203:
6200:
6198:
6195:
6193:
6190:
6188:
6185:
6183:
6180:
6178:
6175:
6173:
6170:
6168:
6165:
6163:
6160:
6158:
6155:
6153:
6150:
6148:
6145:
6143:
6140:
6138:
6135:
6133:
6130:
6128:
6125:
6123:
6120:
6118:
6115:
6113:
6110:
6108:
6105:
6103:
6100:
6098:
6095:
6093:
6090:
6088:
6085:
6083:
6082:Aminophylline
6080:
6078:
6075:
6073:
6070:
6068:
6065:
6063:
6060:
6058:
6055:
6053:
6050:
6047:
6046:
6043:
6040:
6038:
6035:
6033:
6030:
6028:
6025:
6023:
6020:
6018:
6015:
6013:
6010:
6008:
6005:
6003:
6000:
5998:
5995:
5993:
5990:
5988:
5986:
5982:
5980:
5977:
5975:
5972:
5970:
5967:
5965:
5962:
5960:
5957:
5955:
5952:
5950:
5947:
5945:
5942:
5940:
5937:
5935:
5932:
5930:
5927:
5925:
5922:
5920:
5917:
5915:
5912:
5910:
5907:
5905:
5902:
5900:
5897:
5895:
5892:
5890:
5888:
5883:
5881:
5878:
5876:
5873:
5871:
5868:
5866:
5863:
5861:
5859:
5854:
5851:
5850:
5848:
5845:
5840:
5836:
5830:
5827:
5825:
5822:
5819:
5818:
5816:
5813:
5809:
5805:
5802:
5798:
5792:
5788:
5784:
5781:
5774:
5769:
5767:
5762:
5760:
5755:
5754:
5751:
5735:
5733:
5730:
5729:
5727:
5724:
5721:
5718:
5716:
5713:
5712:
5708:
5698:
5695:
5693:
5690:
5688:
5685:
5684:
5682:
5680:
5676:
5673:
5671:
5667:
5657:
5654:
5652:
5649:
5647:
5644:
5642:
5639:
5638:
5636:
5634:
5630:
5624:
5620:
5616:
5613:
5611:
5608:
5606:
5602:
5599:
5598:
5596:
5594:
5587:
5581:
5578:
5576:
5573:
5571:
5568:
5567:
5565:
5563:
5555:
5547:
5544:
5542:
5539:
5537:
5534:
5532:
5529:
5527:
5524:
5523:
5522:
5519:
5517:
5514:
5512:
5509:
5507:
5504:
5503:
5501:
5498:
5494:
5489:
5485:
5482:
5480:
5475:
5472:
5468:
5458:
5455:
5453:
5450:
5449:
5447:
5444:
5440:
5435:
5431:
5425:
5422:
5420:
5417:
5415:
5412:
5410:
5407:
5405:
5402:
5400:
5397:
5395:
5392:
5390:
5387:
5385:
5382:
5380:
5377:
5375:
5372:
5370:
5367:
5366:
5364:
5361:
5357:
5352:
5348:
5338:
5335:
5333:
5330:
5328:
5325:
5323:
5320:
5318:
5315:
5313:
5310:
5308:
5305:
5304:
5302:
5299:
5294:
5286:
5283:
5281:
5278:
5276:
5273:
5272:
5271:
5270:
5266:
5262:
5259:
5258:
5257:
5256:
5252:
5251:
5249:
5246:
5241:
5235:
5232:
5230:
5227:
5225:
5222:
5220:
5217:
5215:
5212:
5210:
5207:
5205:
5202:
5200:
5197:
5196:
5194:
5191:
5187:
5182:
5179:
5176:
5171:
5167:
5164:
5162:
5158:
5153:
5149:
5142:
5137:
5135:
5130:
5128:
5123:
5122:
5119:
5103:
5100:
5098:
5095:
5093:
5090:
5088:
5085:
5083:
5080:
5078:
5075:
5073:
5070:
5069:
5066:
5060:
5057:
5055:
5052:
5050:
5047:
5045:
5042:
5040:
5037:
5035:
5032:
5030:
5027:
5026:
5023:
5020:
5018:
5014:
5004:
5001:
4999:
4996:
4994:
4991:
4989:
4986:
4984:
4981:
4980:
4977:
4971:
4968:
4966:
4963:
4961:
4958:
4956:
4953:
4951:
4948:
4946:
4943:
4942:
4939:
4936:
4932:
4922:
4919:
4917:
4914:
4912:
4909:
4907:
4904:
4902:
4899:
4897:
4894:
4893:
4891:
4889:
4885:
4879:
4876:
4874:
4871:
4869:
4866:
4864:
4861:
4859:
4856:
4854:
4851:
4849:
4846:
4845:
4843:
4841:
4837:
4831:
4828:
4826:
4823:
4821:
4818:
4816:
4813:
4811:
4808:
4806:
4803:
4801:
4798:
4797:
4795:
4793:
4789:
4786:
4782:
4778:
4768:
4765:
4763:
4760:
4758:
4757:Deoxycytidine
4755:
4753:
4750:
4748:
4745:
4743:
4740:
4738:
4735:
4734:
4732:
4730:
4726:
4720:
4717:
4715:
4712:
4710:
4708:
4704:
4702:
4699:
4697:
4696:Pseudouridine
4694:
4692:
4689:
4687:
4684:
4682:
4679:
4677:
4674:
4672:
4669:
4667:
4664:
4663:
4661:
4659:
4655:
4652:
4650:
4646:
4640:
4637:
4633:
4630:
4628:
4625:
4623:
4620:
4618:
4615:
4614:
4613:
4610:
4606:
4603:
4601:
4598:
4596:
4593:
4591:
4588:
4586:
4583:
4582:
4581:
4578:
4577:
4575:
4573:
4569:
4564:
4557:
4552:
4550:
4545:
4543:
4538:
4537:
4534:
4522:
4521:
4512:
4510:
4509:
4500:
4499:
4496:
4490:
4487:
4485:
4482:
4481:
4479:
4475:
4468:
4465:
4462:
4459:
4456:
4453:
4450:
4447:
4444:
4441:
4438:
4435:
4432:
4429:
4426:
4423:
4420:
4417:
4415:
4412:
4409:
4406:
4404:
4401:
4400:
4398:
4396:
4392:
4388:
4382:
4379:
4377:
4374:
4372:
4369:
4367:
4364:
4362:
4359:
4357:
4354:
4352:
4349:
4346:
4342:
4339:
4338:
4336:
4334:
4333:Organisations
4330:
4324:
4321:
4319:
4316:
4314:
4311:
4309:
4306:
4304:
4301:
4299:
4296:
4294:
4291:
4289:
4286:
4285:
4283:
4279:
4273:
4270:
4267:
4264:
4261:
4258:
4256:
4253:
4251:
4248:
4246:
4243:
4240:
4237:
4234:
4231:
4228:
4225:
4222:
4219:
4217:
4213:
4210:
4208:
4205:
4202:
4199:
4198:
4196:
4194:
4190:
4184:
4181:
4179:
4178:Trauma center
4176:
4174:
4171:
4169:
4166:
4164:
4161:
4159:
4156:
4154:
4151:
4149:
4146:
4144:
4141:
4139:
4136:
4134:
4131:
4129:
4126:
4125:
4123:
4119:
4115:
4108:
4103:
4101:
4096:
4094:
4089:
4088:
4085:
4069:
4062:
4060:
4053:
4051:
4048:
4046:
4039:
4037:
4034:
4033:
4031:
4027:
4017:
4014:
4012:
4005:
4003:
4000:
3999:
3997:
3993:
3983:
3982:Acetylcholine
3980:
3979:
3977:
3973:
3970:
3968:Miscellaneous
3966:
3961:
3958:
3954:
3940:
3937:
3935:
3932:
3930:
3927:
3926:
3924:
3921:
3917:
3914:
3910:
3907:
3904:
3900:
3885:
3881:
3880:
3877:
3874:
3872:
3871:Neurosteroids
3868:
3862:
3859:
3857:
3854:
3852:
3849:
3847:
3844:
3842:
3839:
3837:
3834:
3832:
3829:
3827:
3824:
3822:
3819:
3817:
3814:
3812:
3809:
3807:
3804:
3802:
3799:
3797:
3794:
3792:
3789:
3787:
3784:
3783:
3781:
3777:
3774:
3771:
3767:
3752:
3748:
3747:
3744:
3741:
3739:
3738:Neuropeptides
3735:
3725:
3722:
3721:
3719:
3715:
3709:
3707:
3703:
3701:
3699:
3695:
3693:
3690:
3688:
3685:
3683:
3680:
3678:
3675:
3673:
3671:
3667:
3665:
3663:
3659:
3657:
3654:
3652:
3649:
3647:
3644:
3643:
3641:
3637:
3631:
3628:
3626:
3623:
3621:
3618:
3616:
3613:
3611:
3608:
3606:
3603:
3602:
3600:
3596:
3593:
3591:
3587:
3577:
3574:
3572:
3569:
3568:
3566:
3564:
3560:
3554:
3551:
3549:
3546:
3544:
3541:
3539:
3536:
3534:
3531:
3529:
3526:
3524:
3521:
3519:
3516:
3515:
3513:
3509:
3503:
3500:
3498:
3495:
3493:
3490:
3489:
3487:
3483:
3477:
3474:
3472:
3469:
3467:
3464:
3462:
3459:
3457:
3454:
3452:
3449:
3447:
3444:
3442:
3439:
3437:
3434:
3432:
3429:
3427:
3424:
3422:
3419:
3418:
3416:
3412:
3409:
3403:
3400:
3397:
3393:
3389:
3382:
3377:
3375:
3370:
3368:
3363:
3362:
3359:
3349:
3345:
3340:
3335:
3331:
3327:
3323:
3316:
3308:
3304:
3299:
3294:
3290:
3286:
3282:
3275:
3267:
3263:
3259:
3255:
3251:
3247:
3243:
3239:
3232:
3224:
3220:
3215:
3210:
3206:
3202:
3198:
3191:
3183:
3181:9781416066453
3177:
3173:
3169:
3165:
3161:
3154:
3147:
3132:
3128:
3122:
3114:
3110:
3105:
3100:
3096:
3092:
3089:(4): e13597.
3088:
3084:
3080:
3073:
3065:
3061:
3057:
3053:
3045:
3037:
3033:
3028:
3023:
3019:
3015:
3011:
3004:
2996:
2992:
2988:
2984:
2980:
2976:
2972:
2968:
2960:
2952:
2948:
2943:
2938:
2933:
2928:
2924:
2920:
2916:
2912:
2908:
2901:
2893:
2889:
2884:
2879:
2875:
2871:
2867:
2863:
2859:
2852:
2844:
2840:
2836:
2832:
2825:
2817:
2813:
2808:
2803:
2799:
2795:
2791:
2787:
2783:
2776:
2768:
2764:
2759:
2754:
2749:
2744:
2740:
2736:
2732:
2728:
2724:
2717:
2709:
2705:
2700:
2695:
2691:
2687:
2683:
2679:
2675:
2671:
2667:
2660:
2652:
2648:
2643:
2638:
2634:
2630:
2626:
2622:
2618:
2611:
2603:
2599:
2594:
2589:
2584:
2579:
2575:
2571:
2567:
2563:
2559:
2552:
2544:
2540:
2536:
2532:
2524:
2516:
2510:
2506:
2499:
2484:
2480:
2474:
2466:
2460:
2456:
2452:
2445:
2443:
2434:
2430:
2425:
2420:
2416:
2412:
2408:
2404:
2400:
2393:
2385:
2381:
2376:
2371:
2367:
2363:
2359:
2355:
2351:
2344:
2336:
2332:
2327:
2322:
2317:
2312:
2308:
2304:
2300:
2293:
2285:
2281:
2276:
2271:
2266:
2261:
2257:
2253:
2249:
2242:
2234:
2230:
2226:
2222:
2218:
2214:
2207:
2199:
2195:
2190:
2185:
2181:
2177:
2173:
2169:
2165:
2158:
2150:
2146:
2141:
2136:
2132:
2128:
2124:
2120:
2116:
2109:
2101:
2095:
2091:
2084:
2076:
2072:
2068:
2064:
2060:
2056:
2052:
2048:
2041:
2033:
2029:
2025:
2021:
2014:
2006:
2002:
1996:
1988:
1984:
1979:
1974:
1969:
1964:
1960:
1956:
1952:
1945:
1937:
1933:
1928:
1923:
1918:
1913:
1909:
1905:
1901:
1894:
1878:
1871:
1865:
1857:
1853:
1849:
1845:
1841:
1837:
1829:
1821:
1819:0-7923-6170-9
1815:
1811:
1804:
1790:
1786:
1782:
1778:
1771:
1769:
1760:
1756:
1752:
1748:
1741:
1733:
1729:
1725:
1721:
1716:
1711:
1707:
1703:
1699:
1692:
1684:
1680:
1676:
1672:
1668:
1664:
1657:
1649:
1645:
1641:
1637:
1632:
1631:11392/2391482
1627:
1622:
1617:
1613:
1609:
1605:
1598:
1590:
1588:0-7167-4339-6
1584:
1580:
1573:
1565:
1563:3-540-33047-X
1559:
1555:
1551:
1547:
1540:
1536:
1527:
1524:
1522:
1519:
1517:
1514:
1513:
1507:
1505:
1495:
1493:
1489:
1485:
1482:
1478:
1474:
1470:
1466:
1462:
1458:
1455:
1451:
1448:
1443:
1441:
1437:
1433:
1429:
1425:
1415:
1413:
1409:
1399:
1393:
1389:
1385:
1382:
1378:
1374:
1364:
1362:
1358:
1355:
1347:
1337:
1335:
1331:
1327:
1323:
1319:
1315:
1311:
1307:
1303:
1299:
1293:
1278:
1276:
1272:
1270:
1266:
1262:
1258:
1256:
1252:
1247:
1245:
1241:
1238:
1234:
1224:
1222:
1216:
1214:
1210:
1206:
1202:
1194:
1190:
1180:
1178:
1174:
1170:
1166:
1163:
1153:
1150:
1149:phospholipase
1110:
1106:
1084:
1074:
1072:
1068:
1060:
1056:
1051:
1046:
1044:
1037:
1030:
1023:
1007:
1003:
1000:
999:
998:
996:
986:
984:
983:acetylcholine
980:
972:
968:
965:
961:
957:
953:
949:
942:
938:
934:
930:
928:
919:
917:
913:
909:
905:
901:
897:
893:
889:
884:
882:
878:
874:
864:
862:
859:
855:
845:
843:
839:
835:
830:
828:
824:
820:
816:
812:
807:
805:
801:
797:
793:
788:
786:
771:
769:
765:
761:
757:
753:
750:(abbreviated
749:
745:
743:
739:
735:
731:
727:
723:
719:
715:
711:
703:
699:
695:
691:
688:
684:
674:
667:
661:
652:
647:
646:
643:
636:
627:
626:
623:
616:
609:
605:
604:
602:
599:
594:
587:
585:
581:
554:
552:
548:
543:
539:
535:
532:
530:
528:ECHA InfoCard
524:
516:
512:
511:DTXSID1022558
508:
507:
505:
496:
492:
485:
481:
480:
478:
476:
472:
465:
461:
460:
458:
456:
452:
445:
441:
440:
438:
436:
432:
425:
421:
420:
418:
416:
412:
405:
401:
400:
398:
396:
392:
385:
381:
380:
378:
376:
372:
365:
361:
360:
358:
356:
352:
345:
341:
340:
338:
331:
327:
320:
316:
315:
313:
311:
307:
299:
295:
291:
287:
283:
278:
277:
274:
267:
262:
258:
256:
252:
248:
246:
239:
235:
233:
229:
225:
223:
219:
215:
213:
209:
205:
201:
194:
193:
191:
189:
185:
180:
176:
174:
170:
166:
164:
159:
155:
154:Physiological
151:
143:
138:
135:
134:
132:
130:
126:
122:
120:
114:
110:
104:
103:
101:
99:
93:
89:
85:
83:
79:
75:
71:
67:
63:
61:
57:
54:Clinical data
52:
48:
43:
39:
34:
24:
19:
8536:Vasodilators
8422:Antagonists:
8421:
8406:
8378:Capromorelin
8367:
8365:Non-peptide:
8364:
8276:Alexamorelin
8272:
8269:
8243:Antagonists:
8242:
8192:
8189:
8148:Antagonists:
8147:
8141:Veldoreotide
8027:
7995:
7985:
7971:Antagonists:
7970:
7929:Somatotropin
7870:
7791:
7790:
7775:Chrysophanol
7771:
7715:Hypoxanthine
7644:
7636:
7616:
7612:Pralatrexate
7597:Methotrexate
7592:Azathioprine
7571:Topiroxostat
7548:
7519:Myo-inositol
7506:
7497:Caffeic acid
7410:Progesterone
7380:Dipyridamole
7360:Barbiturates
7337:Progesterone
7301:
7119:AR-C 69931MX
7114:AR-C 67085MX
7086:Antagonists:
7085:
6939:AR-C 67085MX
6918:
6885:
6854:
6832:
6826:
6789:
6756:Oxidized-ATP
6701:JNJ-47965567
6662:
6586:Antagonists:
6585:
6559:L-Ī²,Ī³-Me-ATP
6539:D-Ī²,Ī³-Me-ATP
6488:
6475:
6407:Theophylline
6387:Taminadenant
6302:Paraxanthine
6187:Fenethylline
6182:Etrumadenant
6172:Enprofylline
6137:Ciforadenant
6049:Antagonists:
6048:
6037:Trabodenoson
6007:Piclidenoson
5984:
5893:
5886:
5865:2-Cl-IB-MECA
5857:
5852:
5843:
5820:
5679:Na/ K-ATPase
5610:Disopyramide
5580:Barbiturates
5569:
5520:
5267:
5253:
5224:Procainamide
5204:Disopyramide
4762:Deoxyinosine
4752:Deoxyuridine
4706:
4665:
4595:Hypoxanthine
4565:constituents
4563:Nucleic acid
4513:
4501:
4395:Life support
4287:
4173:Major trauma
4036:Acetaldehyde
3919:
3705:
3697:
3669:
3661:
3639:Trace amines
3329:
3325:
3315:
3288:
3285:Hypertension
3284:
3274:
3241:
3237:
3231:
3204:
3200:
3190:
3163:
3159:
3146:
3135:. Retrieved
3133:. 2022-06-07
3130:
3121:
3086:
3082:
3072:
3055:
3051:
3044:
3017:
3013:
3003:
2970:
2966:
2959:
2914:
2910:
2900:
2865:
2861:
2851:
2834:
2830:
2824:
2789:
2785:
2775:
2733:(5): e2107.
2730:
2726:
2716:
2673:
2669:
2659:
2624:
2620:
2610:
2565:
2561:
2551:
2534:
2530:
2523:
2504:
2498:
2487:. Retrieved
2482:
2473:
2454:
2406:
2402:
2392:
2357:
2353:
2343:
2306:
2302:
2292:
2258:(12): 3837.
2255:
2251:
2241:
2219:(1): 33ā39.
2216:
2212:
2206:
2171:
2167:
2157:
2122:
2118:
2108:
2089:
2083:
2050:
2046:
2040:
2023:
2019:
2013:
2005:the original
2001:"Vitamin B4"
1995:
1958:
1954:
1944:
1907:
1903:
1893:
1881:. Retrieved
1879:. April 2016
1876:
1864:
1839:
1835:
1828:
1812:. Springer.
1809:
1803:
1792:. Retrieved
1780:
1750:
1746:
1740:
1705:
1701:
1691:
1666:
1662:
1656:
1611:
1607:
1597:
1578:
1572:
1545:
1539:
1504:vasodilation
1501:
1498:Vasodilation
1492:cannabinoids
1481:CB1 receptor
1444:
1421:
1405:
1392:Trk receptor
1370:
1361:Methotrexate
1359:
1343:
1312:and rise in
1306:dengue virus
1295:
1273:
1261:Dipyridamole
1259:
1248:
1236:
1230:
1217:
1186:
1159:
1086:
1067:inflammatory
1047:
1016:
992:
969:
956:theophylline
946:
927:Dipyridamole
925:
888:dipyridamole
885:
870:
856:(TI 201) or
851:
831:
808:
789:
782:
774:Medical uses
755:
751:
747:
746:
689:
682:
681:
670:
664:
297:
293:
289:
285:
281:
242:Elimination
188:Legal status
182:Legal status
108:
18:
8521:Nucleosides
8398:Macimorelin
8356:Tabimorelin
8351:Relamorelin
8331:Lenomorelin
8236:Tesamorelin
8231:Somatorelin
8166:Satoreotide
8091:Pasireotide
8076:NNC 26-9100
8056:Ilatreotide
8051:Edotreotide
7989:Atesidorsen
7979:Pegvisomant
7954:Somavaratan
7944:Sometribove
7919:Somapacitan
7914:Somagrebove
7637:Precursors:
7617:Many others
7587:Aminopterin
7544:Phytic acid
7487:Amflutizole
7482:Allopurinol
7438:Decynium-22
7395:Hexobendine
7267:Transporter
7244:Ticlopidine
7149:Clopidogrel
7059:UDP-glucose
6798:Purotoxin 1
6629:AZ-11645373
6624:AZ-10606120
6417:Tracazolate
6397:Theobromine
6372:SCH-442,416
6367:Rolofylline
6312:Preladenant
6202:Inupadenant
6197:Imaradenant
6117:Cartazolate
6097:Bamifylline
6032:Tecadenoson
6027:Sonedenoson
6022:Selodenoson
6017:SDZ WAG 994
6012:Regadenoson
5992:Namodenoson
5934:Capadenoson
5929:Binodenoson
5924:BAY 60ā6583
5722:from market
5633:Ī± receptors
5516:Propranolol
5479:antagonists
5424:Vernakalant
5394:Dronedarone
5337:Propafenone
5322:Indecainide
4272:Pocket mask
4148:Golden hour
4041:Ammonia (NH
3912:Nucleosides
3672:-Octopamine
3664:-Octopamine
3576:T-HCA (GHC)
3533:Hypotaurine
3485:GABA system
3436:Glutathione
3326:Circulation
1477:sleep cycle
1475:during the
1209:endothelium
1189:heart block
975:adenosine A
960:theobromine
798:(AVRT) and
768:radical SAM
764:vitamin B12
591: gĀ·mol
534:100.000.354
464:CHEBI:16335
264:Identifiers
123:Intravenous
69:Other names
60:Trade names
8490:Categories
8373:Anamorelin
8361:Ulimorelin
8336:Livoletide
8326:Ipamorelin
8226:Sermorelin
8221:Rismorelin
8161:CYN-154806
8136:Vapreotide
8086:Octreotide
8081:Octreotate
8071:Lanreotide
8046:Depreotide
7964:Somidobove
7959:Somavubove
7924:Somatosalm
7849:modulators
7607:Pemetrexed
7566:Tisopurine
7539:Oxipurinol
7534:Niraxostat
7524:Kaempferol
7514:Febuxostat
7458:inhibitors
7370:Cilostazol
7332:Phloridzin
7239:Ticagrelor
7109:AR-C 66096
6969:Diquafosol
6914:Ī±,Ī²-Me-ATP
6899:2-Thio-UTP
6808:Ro 0437626
6761:Phenol Red
6676:Gefapixant
6671:Evans blue
6554:Ivermectin
6484:Ī±,Ī²-Me-ATP
6447:nucleotide
6432:ZM-241,385
6422:Vipadenant
6412:Tozadenant
6297:Muvadenant
6242:MRE3008F20
6237:Lu AA47070
6232:Lu AA41063
6167:Dyphylline
6152:Dimethazan
6077:Acefylline
6042:UK-432,097
5959:Evodenoson
5949:CP-532,903
5909:Apadenoson
5783:modulators
5641:Amiodarone
5546:Metoprolol
5526:Acebutolol
5497:Ī² blockers
5409:Nifekalant
5389:Dofetilide
5384:Celivarone
5369:Amiodarone
5332:Moracizine
5327:Lorcainide
5317:Flecainide
5312:Ethacizine
5296:class Ic (
5280:Mexiletine
5243:class Ib (
5219:Prajmaline
5184:class Ia (
4781:Nucleotide
4719:Wybutosine
4714:Xanthosine
4649:Nucleoside
4612:Pyrimidine
4572:Nucleobase
4484:NACA score
4293:Amiodarone
4207:Chest tube
4029:Candidates
3903:Nucleobase
3692:Tryptamine
3687:Synephrine
3598:Monoamines
3563:GHB system
3396:Amino acid
3137:2023-04-12
2489:2021-03-22
1978:10451/6361
1794:2022-01-28
1781:StatPearls
1532:References
1484:activation
1457:anandamide
1428:sleepiness
1398:receptor.
1318:flavivirus
1290:See also:
1227:Metabolism
1162:endogenous
941:antagonist
918:patients.
838:cardiovert
823:ventricles
714:nucleoside
596:3D model (
584:Molar mass
424:K72T3FS567
395:ChemSpider
355:IUPHAR/BPS
310:CAS Number
273:IUPAC name
232:Metabolism
173:Metabolism
8415:LY-444711
8410:LY-426410
8407:Unsorted:
8403:SM-130686
8393:L-692,585
8383:CP-464709
8368:Adenosine
8341:LY-444711
8270:Agonists:
8261:(ghrelin)
8206:Dumorelin
8196:ALRN-5281
8190:Agonists:
8151:BIM-23056
8106:Seglitide
8066:L-817,818
8061:L-803,087
8031:BIM-23052
8028:Agonists:
7974:G120K-hGH
7871:Agonists:
7846:signaling
7792:See also:
7695:Guanosine
7645:Adenosine
7561:Quercetin
7529:Myricetin
7385:Estradiol
7312:Estradiol
7302:Adenosine
7214:Prasugrel
7154:Elinogrel
7144:Cangrelor
7089:2-Me-SAMP
7029:PAPET-ATP
6989:INS-37217
6964:Denufosol
6919:Adenosine
6909:5-OMe-UDP
6894:2-Me-SATP
6889:2-Me-SADP
6886:Agonists:
6781:PSB-12062
6716:Magnesium
6681:GW-791343
6569:PAPET-ATP
6489:Adenosine
6479:2-Me-SATP
6476:Agonists:
6392:Theacrine
6377:SCH-58261
6362:Reversine
6212:ISAM-R316
6177:Etazolate
6127:CGS-15943
6102:Cafedrine
5944:CGS-21680
5894:Adenosine
5875:2'-MeCCPA
5853:Agonists:
5844:adenosine
5821:Agonists:
5732:Phase III
5720:Withdrawn
5687:Digitoxin
5656:Verapamil
5651:Quinidine
5646:Bretylium
5615:Quinidine
5570:Adenosine
5541:Landiolol
5457:Verapamil
5452:Diltiazem
5419:Tedisamil
5404:Ibutilide
5379:Bunaftine
5374:Bretylium
5351:class III
5307:Encainide
5285:Tocainide
5275:Aprindine
5261:Lidocaine
5234:Sparteine
5229:Quinidine
5214:Lorajmine
4747:Thymidine
4671:Guanosine
4666:Adenosine
4403:First aid
4288:Adenosine
4255:Combitube
4229:(ECG/EKG)
4193:Equipment
3920:Adenosine
3724:Histamine
3708:-Tyramine
3700:-Tyramine
3543:Sarcosine
3523:Ī²-Alanine
3518:Ī±-Alanine
2309:(1): 52.
2075:235094871
1408:minoxidil
1388:glutamate
1314:cytokines
914:, and in
770:enzymes.
704:via a Ī²-N
683:Adenosine
484:ChEMBL477
255:Excretion
244:half-life
117:Routes of
96:Pregnancy
88:Monograph
82:Drugs.com
30:Adenosine
8476:instead.
8425:A-778193
8286:EP-51216
8273:Peptide:
8246:MZ-5-156
8201:CJC-1295
8193:Peptide:
7939:Somatrem
7670:Cytidine
7665:Cytosine
7556:Propolis
7322:KGO-2173
7317:KGO-2142
7307:dMeThPmR
7273:blockers
7229:Regrelor
7219:PSB-0739
7189:MRS-2578
7184:MRS-2500
7179:MRS-2395
7174:MRS-2279
7169:MRS-2211
7164:MRS-2179
7039:PSB-1114
7034:PSB-0474
7019:MRS-4062
7014:MRS-2957
7009:MRS-2768
7004:MRS-2693
6999:MRS-2690
6994:MRS-2365
6904:5-Br-UDP
6846:TC-P 262
6786:Puerarin
6721:MRS-2159
6696:isoPPADS
6614:A-839977
6609:A-804598
6604:A-740003
6599:A-438079
6594:A-317491
6564:MRS-2219
6427:VUF-5574
6357:PSB-1901
6352:PSB-1115
6277:MRS-3777
6272:MRS-1754
6267:MRS-1706
6262:MRS-1523
6257:MRS-1334
6252:MRS-1220
6247:MRS-1191
6227:KF-26777
6207:ISAM-140
6147:CVT-6883
6122:CGH-2466
6107:Caffeine
6092:AZD-4635
5979:LUF-5845
5974:LUF-5835
5964:GR 79236
5914:ATL-146e
5791:Receptor
5605:Atropine
5531:Atenolol
5511:Pindolol
5488:class II
5474:agonists
5471:Receptor
5434:class IV
5199:Ajmaline
4911:c-di-AMP
4906:c-di-GMP
4691:Cytidine
4627:Cytosine
4600:Xanthine
4508:Category
4469:(CCrISP)
4313:Naloxone
4303:Dopamine
4298:Atropine
3959:-derived
3905:-derived
3886:instead.
3841:Oleamide
3772:-derived
3753:instead.
3610:Dopamine
3421:Agmatine
3398:-derived
3258:15772334
3223:14746372
3113:35575450
3064:24183218
3036:22020741
2995:12289511
2987:19239555
2951:11248116
2892:12151508
2843:21044428
2816:18846036
2767:18461129
2727:PLOS ONE
2708:24590073
2651:15388457
2602:19918064
2433:21917810
2384:23601906
2335:31878283
2284:30513816
2233:14698282
2198:18758473
2149:18311158
2067:34019396
1987:20164566
1936:32166015
1883:10 April
1789:30725774
1759:19000353
1732:21575090
1683:16525141
1648:44107679
1640:29848236
1510:See also
1447:cannabis
1436:insomnia
1410:in male
1384:dopamine
1377:Caffeine
1281:Research
1201:receptor
1173:appetite
1059:ischemia
1050:ischemic
979:receptor
971:Caffeine
952:caffeine
937:Caffeine
892:diazepam
854:thallium
842:asystole
748:Adenosyl
692:) is an
673:(verify)
375:DrugBank
129:ATC code
98:category
8526:Purines
8449:YIL-781
8444:JMV2959
8296:Ghrelin
8126:SRIF-28
8121:SRIF-14
7779:rhubarb
7772:Others:
7750:Uridine
7720:Inosine
7690:Guanine
7640:Adenine
7390:Ethanol
7375:Dilazep
7327:MeThPmR
7234:Suramin
7139:C1330-7
6984:INS-365
6863:TNP-ATP
6841:Suramin
6639:Calcium
6347:PSB-788
6342:PSB-603
6087:ATL-444
5954:CV-1808
5829:Adenine
5812:adenine
5797:ligands
5697:Ouabain
5692:Digoxin
5623:Digoxin
5562:agonist
5536:Esmolol
5506:Nadolol
5493:Phase 4
5439:Phase 4
5414:Sotalol
5356:Phase 3
5298:Phase 0
5269:enteral
5245:Phase 3
5190:Phase 3
5186:Phase 0
5170:class I
4701:Inosine
4681:Uridine
4622:Thymine
4590:Guanine
4585:Adenine
4520:Outline
4445:(ACoRN)
4391:Courses
3957:Vitamin
3851:RVD-HpĪ±
3806:AA-5-HT
3553:Taurine
3538:Proline
3528:Glycine
3471:Proline
3441:Glycine
3348:1884445
3307:9576114
3104:9541543
2919:Bibcode
2883:6758129
2807:2579671
2758:2329854
2735:Bibcode
2699:7095208
2678:Bibcode
2593:2787148
2570:Bibcode
2543:8020339
2424:3328085
2375:3674206
2326:7016859
2275:6321150
2189:2568887
2140:2268070
2032:7752065
1927:7052475
1856:1514488
1724:6376597
1375:(CNS).
1334:Marburg
1326:BCX4430
1310:viremia
1304:of the
1298:NITD008
1286:Viruses
1237:de novo
1191:in the
1167:of the
1165:agonist
1099:, and A
1055:hypoxia
993:Common
916:elderly
908:hypoxia
825:(e.g.,
813:(e.g.,
756:5'-dAdo
698:adenine
589:267.245
551:Formula
384:DB00640
330:PubChem
319:58-61-7
163:tissues
161:Source
145:)
139: (
137:C01EB10
23:adenine
8321:GHRP-6
8316:GHRP-5
8311:GHRP-4
8306:GHRP-3
8301:GHRP-1
8131:TT-232
8101:RC-160
8036:CH-275
7745:Uracil
7740:Ribose
7630:Others
7580:Others
7452:Enzyme
7199:NF-340
7194:NF-157
7094:A3P5PS
7024:NF-546
6746:NF-449
6741:NF-279
6736:NF-157
6731:NF-110
6726:NF-023
6659:Emodin
6654:Copper
6619:AF-353
6589:5-BDBD
6549:HT-AMP
6337:PSB-36
6332:PSB-11
6327:PSB-10
5969:HENECA
5715:WHO-EM
5399:E-4031
5188:ā and
4617:Uracil
4580:Purine
4463:(ALSO)
4457:(PALS)
4451:(PBLS)
4433:(ATLS)
4427:(ACLS)
4183:Triage
3922:system
3796:2-ALPI
3717:Others
3548:Serine
3476:Serine
3346:
3305:
3264:
3256:
3221:
3178:
3111:
3101:
3062:
3034:
2993:
2985:
2949:
2939:
2890:
2880:
2841:
2814:
2804:
2765:
2755:
2706:
2696:
2670:Nature
2649:
2642:521892
2639:
2600:
2590:
2541:
2511:
2483:KIMITO
2461:
2431:
2421:
2382:
2372:
2333:
2323:
2282:
2272:
2231:
2196:
2186:
2147:
2137:
2096:
2073:
2065:
2030:
1985:
1934:
1924:
1854:
1816:
1787:
1757:
1730:
1722:
1681:
1646:
1638:
1585:
1560:
1103:) are
1038:, and
1002:Asthma
964:purine
950:(e.g.
867:Dosage
702:ribose
687:symbol
622:SMILES
475:ChEMBL
444:C00212
8460:IGF-1
7841:IGF-1
7400:NBMPR
7209:PPADS
7134:BzATP
7099:AMPĪ±S
7079:UTPĪ³S
7049:UDPĪ²S
6949:ATPĪ³S
6929:ADPĪ²S
6813:Ro 51
6776:PPNDS
6771:PPADS
6711:KN-62
6706:KN-04
6524:BzATP
6519:ATPĪ³S
6292:MSX-4
6287:MSX-3
6282:MSX-2
6162:DPCPX
4921:cGAMP
4916:cADPR
4439:(NRP)
4421:(BLS)
4410:(CPR)
4281:Drugs
4268:(OPA)
4262:(NPA)
4203:(BVM)
3831:NAGly
3770:Lipid
3605:6-OHM
3497:GABOB
3266:71178
3262:S2CID
3201:Sleep
3156:(PDF)
2991:S2CID
2942:30691
2303:Cells
2071:S2CID
1873:(PDF)
1728:S2CID
1644:S2CID
1461:sleep
1418:Sleep
1330:Ebola
1139:and A
904:shock
821:) or
811:atria
642:InChI
598:JSmol
455:ChEBI
404:54923
344:60961
8474:here
8472:See
8211:GHRH
8177:GHRH
8015:GHIH
8000:GHBP
7843:axis
7426:PMAT
7348:ENTs
7285:CNTs
7224:RB-2
7159:Ip5I
7104:Ap4A
7069:Up3U
6959:dATP
6934:Ap3A
6868:Zinc
6818:RO-3
6803:RB-2
6691:Ip5I
6579:Zinc
6509:Ap5A
6504:Ap4A
6192:IBMX
6157:DMPX
5997:NECA
5939:CCPA
5477:and
5152:C01B
5102:dXTP
5097:dITP
5092:dCTP
5087:dUTP
5082:dTTP
5077:dGTP
5072:dATP
5039:mUTP
5003:dCDP
4998:dUDP
4993:dTDP
4988:dGDP
4983:dADP
4955:mUDP
4901:cGMP
4896:cAMP
4878:dXMP
4873:dIMP
4868:dCMP
4863:dUMP
4858:dTMP
4853:dGMP
4848:dAMP
4810:mUMP
4241:(IV)
4235:(IO)
3884:here
3882:See
3826:NADA
3801:2-OG
3786:2-AG
3751:here
3749:See
3492:GABA
3466:NAAG
3451:GSSG
3446:GSNO
3344:PMID
3303:PMID
3254:PMID
3219:PMID
3176:ISBN
3109:PMID
3060:PMID
3032:PMID
2983:PMID
2947:PMID
2888:PMID
2839:PMID
2812:PMID
2763:PMID
2704:PMID
2647:PMID
2598:PMID
2539:PMID
2509:ISBN
2459:ISBN
2429:PMID
2380:PMID
2331:PMID
2280:PMID
2229:PMID
2194:PMID
2145:PMID
2094:ISBN
2063:PMID
2028:PMID
1983:PMID
1932:PMID
1885:2023
1852:PMID
1814:ISBN
1785:PMID
1755:PMID
1747:CJEM
1720:PMID
1679:PMID
1636:PMID
1583:ISBN
1558:ISBN
1465:rats
1402:Hair
1386:and
1332:and
1242:via
817:and
435:KEGG
415:UNII
364:2844
206:data
156:data
78:AHFS
8257:GHS
7765:UTP
7760:UDP
7755:UMP
7735:ITP
7730:IDP
7725:IMP
7710:GTP
7705:GDP
7700:GMP
7685:CTP
7680:CDP
7675:CMP
7660:ATP
7655:ADP
7650:AMP
7249:UDP
7204:PIT
7129:ATP
7074:UTP
7044:UDP
6979:ITP
6974:IDP
6954:CTP
6944:ATP
6924:ADP
6878:P2Y
6686:HMA
6634:BBG
6574:UTP
6544:GTP
6534:CTP
6514:ATP
6499:AMP
6494:ADP
6463:ATP
6457:P2X
6142:CPX
5919:ATP
5904:AMP
5899:ADP
5885:5'-
5495:ā,
5441:ā,
5358:ā,
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