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Anti-sigma factors

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392: 187: 36: 267:(RIP) mechanism allows signal transduction across membranes. This mechanism is often used to regulate ECF sigma factors. The mechanism involves two sequential cleavages, the first being an external cleavage of membrane-traversing anti-sigma factor and the second cleavage of the anti-sigma factors in the membrane's plane, resulting in a free cytoplasmic domain. 435:
and other similar bacteria. Sigma B is a stress response factor that plays a role in survival and against destruction that could be caused by other organisms such as mammals. General stress responses that are controlled by Sigma B are stimulated by things like temperature, salt concentration, energy
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Anti-anti-sigma factors allow for the dissociation of the matching anti-sigma factor from its sigma factors, thought binding to the anti-sigma factor, forcing its release from the sigma factor. This allows for tighter regulation of the transcription of genes as a response to environmental conditions.
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and recognizes a promoter, causing inhibition of the stimuli. Because Sigma B orthologs are conserved in various gram-positive bacteria, this anti-sigma factor plays an essential role in the evolution of different bacteria and their ability to respond to stressing factors. Scientist have found that
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anti-sigma factors. The differences in these sigma factors are where in the cell they are bound. Cytoplasmic-bound anti-sigma factors include FlgM, DnaK, RssB, and HscC. Inner membrane-bound anti-sigma factors, also called extra-cytoplasmic function (ECF) anti-sigma factors, include FecR and RseA.
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is not under stress conditions, it is negatively regulated by the anti-sigma factor, Rsbw. RsbW is an anti-sigma factor that regulates another anti-sigma factor, sigma B. RsbW binds to sigma B and prevents it from forming an RNA polymerase holoenzyme. However, in stressed conditions, the
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activity in regulating prokaryote gene expression. Anti-sigma factors have both a sigma-binding domain and a sensory/signaling domain; this allows them to respond to signals inside and outside the cell. Anti-sigma factors have been found in several bacteria, including
295:. The sigma factor can be regulated when the anti-sigma factor is transcribed and the anti-sigma factor when the sigmas gene is transcribed. Sigma factors 70 and 54 don't have specific anti-sigma factors; they have other negative feedback loop mechanisms. 1241:
Ohnishi K, Kutsukake K, Suzuki H, Lino T (November 1992). "A novel transcriptional regulation mechanism in the flagellar regulon of Salmonella typhimurium: an antisigma factor inhibits the activity of the flagellum-specific sigma factor, sigma F".
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the anti-sigma factor, allowing the anti-sigma factor to switch partners and bind to the anti-anti-sigma factor. This frees the sigma factors to activate the gene. Environmental stressors, such as heat, often activate this mechanism.
209:; anti-sigma factors are proteins that inhibit the activities of sigma factors affected by several mechanisms. These mechanisms include adding up the anti-sigma factor between sigma or twisting the anti-sigma factor around sigma— 227:
Research shows anti-sigma factors have more activities than contouring sigma factors effects. Anti-sigma factors can also activate some cells while inhibiting others, meaning they have an essential role in cell function.
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The direct signaling mechanism is as it sounds: the anti-sigma factor binds to a signal, which causes conformation changes in the structure of the anti-sigma factors, resulting in the release of the sigma factors.
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unphosphorylated form of the protein, RsbV, competes with Sigma B for binding to RsbW. RsbV binds to RsbW, allowing sigma B to bind to the core RNA polymerase, resulting in the expression of stress response.
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has seven main sigma factors, five of which have a specific anti-sigma factor. The anti-sigma factor binding to its sigma factors depends upon environmental cues. This mechanism blocks the
194:, ready to transcribe the gene ahead. On the right side of the picture, the anti-sigma factor binds to the sigma factor, kicking out RNAP and terminating transcription of the gene in front. 166:. Anti-sigma factors have an antagonistic effect on sigma factors. Each sigma factor has an associated anti-sigma factor that regulates it. These anti-sigma factors are divided into 1372: 251:
complex. A cell that is not under stress has an anti-sigma factor that is bound to the sigma factor on the gene and keeps it inactive. In times of stress, a phosphatase complex
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There are three main categories for triggering the release of sigmas factors from anti-sigma factors: partner switching, direct signaling, and a mechanism regulated by
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ECF anti-sigma factors tend to be more diverse in genetic sequence than cytoplasmic-bound anti-sigma factors. These factors regulate many cellular processes, such as
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AsiA is an anti-sigma factor gene that is required for bacteriophage T4 to be developed). Which means that AsiA is an essential anti-sigma factor in bacteriophage.
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of genes that are unnecessary in new conditions. The table below shows five sigma factors, what process it affects, and its corresponding anti-sigma factor. In
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and development. Gene regulation has many different layers of regulators. Yet, initiating transcription is crucial in controlling which genes are expressed.
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Anti-anti-sigma factors can thereby function as negative or positive regulatory elements, depending on the corroding sigma factor and gene involved.
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loop, maintaining proper levels of both contrasting factors as there can only be one anti-sigma factor per sigma factor that is transcribed.
2840: 6635: 6619: 1438: 2692: 5408: 5403: 5398: 5393: 5388: 2477: 2470: 2465: 2453: 2448: 2443: 2438: 2433: 2361: 1316:"The anti-anti-sigma factor BldG is involved in activation of the stress response sigma factor σ(H) in Streptomyces coelicolor A3(2)" 6357: 4480: 855:"The Anti-Anti-Sigma Factor BldG Is Involved in Activation of the Stress Response Sigma Factor σH in Streptomyces coelicolor A3(2)" 5568: 5563: 5513: 5503: 5483: 5468: 5448: 5373: 5353: 4495: 4490: 3156: 100: 4724: 4682: 4677: 4672: 4610: 4444: 4232: 4183: 4178: 2225: 2215: 72: 1136:"The Stress-Responsive Alternative Sigma Factor SigB of Bacillus subtilis and Its Relatives: An Old Friend With New Functions" 1010:"The Stress-Responsive Alternative Sigma Factor SigB of Bacillus subtilis and Its Relatives: An Old Friend With New Functions" 79: 6120: 2012: 1584: 1069:"Bacillus subtilis sigma B is regulated by a binding protein (RsbW) that blocks its association with core RNA polymerase" 264: 53: 6389: 5288: 3375: 2833: 2828: 2756: 2746: 1623: 1613: 1448: 828: 620: 119: 17: 86: 2751: 2665: 5687: 2963: 2953: 1554: 1433: 247:. It consists of four key players: a sigma factor, an anti-sigma factor, an anti-anti-sigma factor, and an input 3318: 2958: 2653: 68: 57: 6600: 6595: 5746: 2658: 220:
Anti-sigma factors are simultaneously transcribed with their associated sigma factor. This pairing creates a
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Kang JG, Paget MS, Seok YJ, Hahn MY, Bae JB, Hahn JS, Kleanthous C, Buttner MJ, Roe JH (August 1999).
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the anti- sigma factor, Sigma B controls more than 150 genes that are influential in stress response.
6352: 3233: 3218: 3201: 3196: 3191: 3186: 3097: 3072: 2948: 2860: 2850: 2007: 1480: 818: 1357: 904:"Mutational analysis of RsrA, a zinc-binding anti-sigma factor with a thiol-disulphide redox switch" 659:"Anti-Sigma Factors in E. coli: Common Regulatory Mechanisms Controlling Sigma Factors Availability" 6811: 6094: 5729: 5245: 4818: 4657: 3592: 3587: 3572: 3047: 3022: 2904: 2855: 2648: 2039: 1505: 712: 214: 146: 6459: 4500: 3817: 2931: 2919: 284: 46: 536:"The E. coli Anti-Sigma Factor Rsd: Studies on the Specificity and Regulation of Its Expression" 93: 6590: 4637: 4632: 3027: 2924: 2719: 2680: 1743: 1392: 244: 6582: 6142: 2941: 2877: 2872: 2685: 1761: 853:
Sevcikova, Beatrica; Rezuchova, Bronislava; Homerova, Dagmar; Kormanec, Jan (November 2010).
396: 6163: 6155: 3993: 3475: 3000: 2995: 2990: 2670: 2553: 1388: 1080: 547: 8: 6477: 6181: 5877: 4080: 3285: 2867: 2845: 2818: 2780: 2714: 1084: 551: 6015: 1340: 1315: 1267: 1255: 1224: 1199: 1170: 1135: 1044: 1009: 985: 952: 933: 879: 854: 795: 770: 748: 683: 658: 578: 535: 511: 484: 1297: 1280: 612: 485:"Bacterial Sigma Factors and Anti-Sigma Factors: Structure, Function and Distribution" 5597: 5588: 5225: 4173: 2914: 2909: 1345: 1302: 1259: 1229: 1175: 1157: 1116: 1111: 1098: 1068: 1049: 1031: 990: 972: 925: 920: 903: 884: 824: 800: 740: 732: 688: 634: 626: 616: 583: 565: 516: 431: 292: 252: 221: 202: 1271: 752: 4124: 4106: 2675: 2622: 2396: 1335: 1327: 1292: 1251: 1219: 1211: 1165: 1147: 1106: 1088: 1039: 1021: 980: 968: 964: 937: 915: 902:
Paget MS, Bae JB, Hahn MY, Li W, Kleanthous C, Roe JH, Buttner MJ (February 2001).
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Sigma B was the first anti-sigma factor identified in a bacterium. It is found in
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Kang JG, Paget MS, Seok YJ, Hahn MY, Bae JB, Hahn JS, et al. (August 1999).
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Treviño-Quintanilla LG, Freyre-González JA, Martínez-Flores I (September 2013).
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Proceedings of the National Academy of Sciences of the United States of America
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Kazmierczak, Mark J.; Wiedmann, Martin; Boor, Kathryn J. (December 2005).
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polymerase in order that direct exclusive transcription of its own genes.
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Rodriguez Ayala, Facundo; Bartolini, Marco; Grau, Roberto (2020-09-15).
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Sevcikova B, Rezuchova B, Homerova D, Kormanec J (November 2010).
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Rodriguez Ayala, Facundo; Bartolini, Marco; Grau, Roberto (2020).
953:"Alternative Sigma Factors and Their Roles in Bacterial Virulence" 852: 6507: 6487: 6482: 6194: 4168: 3952: 1864: 1859: 1854: 1842: 1837: 138: 6688: 6683: 6678: 6668: 6663: 6382: 5937: 5932: 5927: 5922: 5188: 5183: 5060: 5055: 5050: 5035: 5026: 5021: 5016: 4995: 4909: 4904: 4692: 4687: 4667: 4662: 4652: 4647: 4485: 4437: 4432: 4427: 4422: 4392: 4387: 4382: 4377: 4347: 4297: 4292: 4055: 3975: 3947: 3942: 3937: 3932: 3927: 3922: 3917: 3912: 3907: 3902: 3897: 3892: 3887: 3882: 3877: 3872: 3867: 3862: 3852: 3847: 3842: 3837: 3832: 3827: 3822: 3812: 3807: 3802: 3762: 3715: 3710: 3705: 3700: 3695: 3690: 3680: 3668: 3663: 3429: 3424: 3419: 3301: 3296: 3268: 3263: 3248: 3243: 3238: 3228: 3223: 3211: 3206: 2578: 2573: 2568: 2563: 2558: 2533: 2460: 2428: 2371: 2366: 2153: 2148: 2143: 2027: 1832: 1722: 1717: 1690: 1685: 1680: 1606: 6732: 6710: 6705: 6673: 6562: 6557: 6502: 6497: 6492: 6436: 6345: 6340: 6335: 6330: 6325: 6320: 6315: 6310: 6258: 6253: 6241: 6236: 6231: 6226: 6214: 6209: 6204: 6199: 6168: 6135: 6130: 6125: 6072: 6067: 6062: 6037: 5995: 5990: 5985: 5980: 5975: 5970: 5942: 5895: 5890: 5836: 5831: 5826: 5821: 5798: 5573: 5558: 5553: 5548: 5543: 5538: 5533: 5528: 5523: 5518: 5508: 5498: 5493: 5478: 5473: 5463: 5458: 5453: 5443: 5438: 5433: 5428: 5423: 5418: 5413: 5383: 5378: 5368: 5363: 5348: 5343: 5338: 5333: 5267: 5262: 5257: 5230: 5205: 5173: 5166: 5161: 5067: 5045: 5040: 5012: 4990: 4985: 4980: 4975: 4870: 4865: 4810: 4803: 4798: 4783: 4756: 4417: 4412: 4407: 4402: 4397: 4372: 4367: 4362: 4357: 4352: 4342: 4337: 4332: 4327: 4322: 4317: 4312: 4307: 4302: 4282: 4277: 4272: 4267: 4262: 4257: 4242: 4237: 4062: 4050: 4045: 4040: 4035: 4003: 3998: 3797: 3787: 3782: 3777: 3772: 3767: 3757: 3752: 3747: 3742: 3658: 3648: 3641: 3636: 3631: 3626: 3616: 3560: 3555: 3550: 3545: 3540: 3535: 3530: 3451: 3446: 3441: 3385: 3380: 3279: 3258: 3253: 3127: 3122: 3117: 3112: 3107: 3102: 2309: 2074: 2069: 2064: 2054: 2049: 2044: 2034: 2022: 1972: 1952: 1893: 1881: 1876: 1800: 1793: 1788: 1778: 1771: 1766: 1697: 1628: 1601: 1596: 1579: 1574: 1569: 1564: 1559: 1549: 1537: 1532: 1510: 1500: 1495: 1485: 1133: 1007: 6759: 6754: 6749: 6739: 6727: 6722: 6569: 6552: 6416: 6411: 6406: 6377: 6372: 6305: 6300: 6295: 6290: 6285: 6280: 6275: 6270: 6221: 6115: 6077: 6052: 6047: 6042: 6025: 5917: 5910: 5905: 5786: 5781: 5776: 5771: 5766: 5761: 5756: 5751: 5741: 5734: 5724: 5719: 5707: 5697: 5692: 5675: 5670: 5665: 5648: 5643: 5638: 5613: 5608: 5603: 5321: 5316: 5311: 5306: 5301: 5240: 5215: 5210: 5151: 5146: 5141: 5136: 5131: 5126: 5121: 5116: 5111: 5082: 5077: 4970: 4965: 4960: 4955: 4941: 4936: 4931: 4926: 4921: 4892: 4887: 4882: 4848: 4843: 4838: 4833: 4828: 4823: 4788: 4776: 4771: 4766: 4719: 4714: 4709: 4704: 4699: 4620: 4605: 4595: 4571: 4566: 4552: 4547: 4542: 4532: 4527: 4515: 4510: 4454: 4449: 4227: 4212: 4207: 4195: 4190: 4023: 4018: 4013: 3857: 3792: 3737: 3732: 3727: 3611: 3606: 3601: 3525: 3520: 3515: 3510: 3505: 3500: 3495: 3490: 3485: 3468: 3463: 3407: 3402: 3370: 3365: 3360: 3350: 3345: 3338: 3333: 3328: 3323: 3313: 3308: 3291: 3149: 3144: 3139: 3067: 2528: 2523: 2518: 2513: 2508: 2503: 2416: 2401: 2378: 2351: 2324: 2319: 2284: 2262: 2257: 2252: 2235: 2230: 2220: 2210: 2160: 2118: 2113: 2096: 2091: 2086: 1984: 1979: 1967: 1925: 1920: 1910: 1825: 1820: 1810: 1729: 1712: 1675: 1663: 1658: 1633: 1591: 1520: 1515: 1490: 1473: 1468: 1463: 1458: 1453: 1443: 352: 339: 312: 213:, especially in bacteria, allows for adaptivity and normal 1240: 652: 650: 648: 534:
Hofmann, Nina; Wurm, Reinhild; Wagner, Rolf (2011-05-06).
6401: 6030: 6020: 5900: 5296: 4853: 4202: 3653: 3390: 2884: 2356: 2185: 2175: 2170: 1962: 1957: 270: 2602: 950: 645: 1200:"RsrA, an anti-sigma factor regulated by redox change" 848: 846: 771:"RsrA, an anti-sigma factor regulated by redox change" 421: 436:
depletion, etc. Once activated, Sigma B binds to the
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Signals release of factors to fix misfolded proteins
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The partner-switching mechanism is commonly found in
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The left side of the picture shows sigma bound to an
6531: 843: 60:. Unsourced material may be challenged and removed. 1197: 768: 604:The extracytoplasmic function (ECF) sigma factors 533: 6803: 4102: 1066: 711:Hughes, Kelly T.; Mathee, Kalai (October 1998). 1067:Benson, A. K.; Haldenwang, W. G. (1993-03-15). 395:Cartoon representation of T4 anti-sigma factor 901: 6792:transcription factor/coregulator deficiencies 5863:β-Scaffold factors with minor groove contacts 1373: 706: 704: 702: 205:that start the transcription by binding with 710: 478: 476: 474: 472: 470: 444: 764: 762: 1380: 1366: 957:Microbiology and Molecular Biology Reviews 699: 377: 1339: 1296: 1223: 1169: 1151: 1110: 1092: 1043: 1025: 984: 919: 878: 794: 682: 577: 559: 510: 500: 467: 120:Learn how and when to remove this message 759: 390: 185: 1278: 600: 368:One signal in the EC signaling pathway 344:Active late gene of flagellum assembly 14: 6804: 6530: 5859: 4101: 2601: 1404: 1403: 1361: 482: 170:-bound anti-sigma factors and inner 58:adding citations to reliable sources 29: 2546:(1.6) Basic helix-span-helix (bHSH) 411:uses anti-sigma factor to ruin the 386: 265:regulated intramembrane proteolysis 24: 1256:10.1111/j.1365-2958.1992.tb01771.x 1190: 179:assembly, transport of materials, 25: 6823: 183:, and the cell's stress response. 921:10.1046/j.1365-2958.2001.02298.x 34: 6533:(0) Other transcription factors 5817:transcriptional enhancer factor 1434:Activating transcription factor 1285:Current Opinion in Microbiology 1127: 1060: 1001: 944: 132: 45:needs additional citations for 969:10.1128/MMBR.69.4.527-543.2005 895: 811: 729:10.1146/annurev.micro.52.1.231 594: 527: 27:Antagonists of a youth's slang 13: 1: 5747:Interferon regulatory factors 3986:(2.5) Alternating composition 3182:General transcription factors 1298:10.1016/S1369-5274(99)80024-1 717:Annual Review of Microbiology 613:10.1016/s0065-2911(02)46002-x 460: 137:Anti-sigma factors are small 5032:Octamer transcription factor 1740:(1.2) Basic helix-loop-helix 561:10.1371/journal.pone.0019235 331:Heat shock response ≥ 37 °C 317:Master regulator of general 231: 7: 1806:Myogenic regulatory factors 675:10.2174/1389202911314060007 10: 6828: 307:Related anti-sigma factor 162:, and viruses such as the 6787: 6649: 6609: 6578: 6543: 6539: 6526: 6468: 6445: 6427: 6177: 6151: 6103: 6006: 5953: 5873: 5869: 5855: 5807: 5626:(3.5) Tryptophan clusters 5624: 5584: 5280: 5097: 4737: 4463: 4151: 4132: 4120: 4116: 4097: 4071: 3984: 3963: 3165: 3085: 3056: 3036: 3011: 2974: 2893: 2789: 2637: 2618: 2614: 2597: 2544: 2489: 2387: 2297: 2273: 2196: 2129: 1993: 1943: 1752: 1738: 1416: 1412: 1399: 1279:Helmann JD (April 1999). 1140:Frontiers in Microbiology 1014:Frontiers in Microbiology 601:Helmann, John D. (2002). 6447:(4.10) Cold-shock domain 1216:10.1093/emboj/18.15.4292 1153:10.3389/fmicb.2020.01761 1027:10.3389/fmicb.2020.01761 787:10.1093/emboj/18.15.4292 713:"The Anti-Sigma Factors" 1393:intracellular receptors 1320:Journal of Bacteriology 859:Journal of Bacteriology 399:' Inhibitor, PDB entry 378:Anti-Anti-Sigma Factors 1244:Molecular Microbiology 1094:10.1073/pnas.90.6.2330 908:Molecular Microbiology 483:Paget MS (June 2015). 405: 293:negative feedback loop 271:Anti-sigma factors in 245:Gram-positive bacteria 195: 6156:TATA-binding proteins 1389:Transcription factors 394: 192:RNA polymerase (RNAP) 189: 1281:"Anti-sigma factors" 215:cell differentiation 69:"Anti-sigma factors" 54:improve this article 6651:(0.6) Miscellaneous 6182:High-mobility group 5878:Rel homology region 2868:Testicular receptor 2609:DNA-binding domains 1332:10.1128/JB.00828-10 1085:1993PNAS...90.2330B 871:10.1128/JB.00828-10 552:2011PLoSO...619235H 502:10.3390/biom5031245 6016:p53 p63 p73 family 5589:Heat shock factors 422:Sigma B Factor in 406: 203:essential proteins 196: 6799: 6798: 6783: 6782: 6779: 6778: 6522: 6521: 6518: 6517: 5851: 5850: 5847: 5846: 5093: 5092: 4733: 4732: 4093: 4092: 4089: 4088: 3081: 3080: 2937:Mineralocorticoid 2593: 2592: 2589: 2588: 2293: 2292: 1406:(1) Basic domains 865:(21): 5674–5681. 820:Molecular Biology 454:Bacillus subtilis 447:Bacillus subtilis 432:Bacillus subtilis 424:Bacillus subtilis 375: 374: 222:negative feedback 130: 129: 122: 104: 18:Anti-sigma factor 16:(Redirected from 6819: 6623:-related factors 6541: 6540: 6528: 6527: 6429:(4.9) Grainyhead 5871: 5870: 5857: 5856: 5809:(3.6) TEA domain 5099:(3.2) Paired box 4740: 4474: 4468: 4162: 4156: 4149: 4148: 4145: 4139: 4130: 4129: 4118: 4117: 4107:Helix-turn-helix 4099: 4098: 3061: 3041: 3016: 2979: 2949:Estrogen related 2898: 2794: 2642: 2635: 2634: 2623:Nuclear receptor 2616: 2615: 2599: 2598: 2278: 2199: 2132: 2001: 1946: 1755: 1750: 1749: 1414: 1413: 1401: 1400: 1382: 1375: 1368: 1359: 1358: 1353: 1343: 1310: 1300: 1275: 1237: 1227: 1204:The EMBO Journal 1184: 1183: 1173: 1155: 1131: 1125: 1124: 1114: 1096: 1079:(6): 2330–2334. 1064: 1058: 1057: 1047: 1029: 1005: 999: 998: 988: 948: 942: 941: 923: 899: 893: 892: 882: 850: 841: 840: 838: 837: 815: 809: 808: 798: 775:The EMBO Journal 766: 757: 756: 708: 697: 696: 686: 663:Current Genomics 654: 643: 642: 598: 592: 591: 581: 563: 531: 525: 524: 514: 504: 480: 413:Escherichia coli 409:T4 bacteriophage 404: 387:In Bacteriophage 298: 297: 273:Escherichia coli 253:dephosphorylates 164:T4 bacteriophage 153:Escherichia coli 125: 118: 114: 111: 105: 103: 62: 38: 30: 21: 6827: 6826: 6822: 6821: 6820: 6818: 6817: 6816: 6812:Gene expression 6802: 6801: 6800: 6795: 6775: 6645: 6605: 6574: 6535: 6514: 6464: 6441: 6423: 6173: 6147: 6099: 6002: 5949: 5865: 5843: 5803: 5620: 5580: 5276: 5089: 4738: 4729: 4470: 4469: 4464: 4459: 4158: 4157: 4152: 4141: 4140: 4133: 4112: 4085: 4067: 3980: 3968: 3959: 3174: 3170: 3161: 3090: 3087:(2.2) Other Cys 3077: 3057: 3052: 3037: 3032: 3012: 3007: 2975: 2970: 2905:Steroid hormone 2894: 2889: 2790: 2785: 2649:Thyroid hormone 2638: 2629: 2610: 2585: 2540: 2485: 2383: 2289: 2276: 2274: 2269: 2197: 2192: 2130: 2125: 1996: 1994: 1989: 1944: 1939: 1753: 1734: 1408: 1395: 1386: 1356: 1326:(21): 5674–81. 1250:(21): 3149–57. 1193: 1191:Further reading 1188: 1187: 1132: 1128: 1065: 1061: 1006: 1002: 949: 945: 900: 896: 851: 844: 835: 833: 831: 817: 816: 812: 767: 760: 709: 700: 655: 646: 623: 599: 595: 532: 528: 481: 468: 463: 450: 427: 400: 389: 380: 319:stress response 276: 234: 211:gene regulation 147:transcriptional 135: 126: 115: 109: 106: 63: 61: 51: 39: 28: 23: 22: 15: 12: 11: 5: 6825: 6815: 6814: 6797: 6796: 6788: 6785: 6784: 6781: 6780: 6777: 6776: 6774: 6773: 6764: 6763: 6762: 6757: 6752: 6742: 6737: 6736: 6735: 6730: 6725: 6715: 6714: 6713: 6708: 6698: 6693: 6692: 6691: 6686: 6681: 6676: 6671: 6666: 6655: 6653: 6647: 6646: 6644: 6643: 6638: 6633: 6627: 6625: 6607: 6606: 6604: 6603: 6598: 6593: 6587: 6585: 6576: 6575: 6573: 6572: 6567: 6566: 6565: 6560: 6549: 6547: 6537: 6536: 6524: 6523: 6520: 6519: 6516: 6515: 6513: 6512: 6511: 6510: 6505: 6500: 6495: 6490: 6485: 6474: 6472: 6466: 6465: 6463: 6462: 6457: 6451: 6449: 6443: 6442: 6440: 6439: 6433: 6431: 6425: 6424: 6422: 6421: 6420: 6419: 6414: 6409: 6404: 6394: 6393: 6392: 6387: 6386: 6385: 6380: 6375: 6360: 6355: 6350: 6349: 6348: 6343: 6338: 6333: 6328: 6323: 6318: 6313: 6308: 6303: 6298: 6293: 6288: 6283: 6278: 6273: 6263: 6262: 6261: 6256: 6246: 6245: 6244: 6239: 6234: 6229: 6219: 6218: 6217: 6212: 6207: 6202: 6192: 6186: 6184: 6175: 6174: 6172: 6171: 6166: 6160: 6158: 6149: 6148: 6146: 6145: 6140: 6139: 6138: 6133: 6128: 6123: 6112: 6110: 6101: 6100: 6098: 6097: 6092: 6091: 6090: 6085: 6080: 6075: 6070: 6065: 6060: 6055: 6050: 6045: 6035: 6034: 6033: 6028: 6023: 6012: 6010: 6008:(4.3) p53-like 6004: 6003: 6001: 6000: 5999: 5998: 5993: 5988: 5983: 5978: 5973: 5962: 5960: 5951: 5950: 5948: 5947: 5946: 5945: 5940: 5935: 5930: 5925: 5915: 5914: 5913: 5908: 5903: 5898: 5893: 5882: 5880: 5867: 5866: 5853: 5852: 5849: 5848: 5845: 5844: 5842: 5841: 5840: 5839: 5834: 5829: 5824: 5813: 5811: 5805: 5804: 5802: 5801: 5796: 5791: 5790: 5789: 5784: 5779: 5774: 5769: 5764: 5759: 5754: 5744: 5739: 5738: 5737: 5732: 5727: 5722: 5712: 5711: 5710: 5705: 5700: 5695: 5685: 5680: 5679: 5678: 5673: 5668: 5658: 5653: 5652: 5651: 5646: 5641: 5630: 5628: 5622: 5621: 5619: 5618: 5617: 5616: 5611: 5606: 5593: 5591: 5582: 5581: 5579: 5578: 5577: 5576: 5571: 5566: 5561: 5556: 5551: 5546: 5541: 5536: 5531: 5526: 5521: 5516: 5511: 5506: 5501: 5496: 5491: 5486: 5481: 5476: 5471: 5466: 5461: 5456: 5451: 5446: 5441: 5436: 5431: 5426: 5421: 5416: 5411: 5406: 5401: 5396: 5391: 5386: 5381: 5376: 5371: 5366: 5361: 5356: 5351: 5346: 5341: 5336: 5326: 5325: 5324: 5319: 5314: 5309: 5304: 5293: 5291: 5278: 5277: 5275: 5274: 5273: 5272: 5271: 5270: 5265: 5260: 5250: 5249: 5248: 5243: 5233: 5228: 5218: 5213: 5208: 5203: 5198: 5193: 5192: 5191: 5186: 5176: 5171: 5170: 5169: 5164: 5156: 5155: 5154: 5149: 5144: 5139: 5134: 5129: 5124: 5119: 5114: 5103: 5101: 5095: 5094: 5091: 5090: 5088: 5087: 5086: 5085: 5080: 5070: 5065: 5064: 5063: 5058: 5053: 5048: 5043: 5038: 5029: 5024: 5019: 5010: 5000: 4999: 4998: 4993: 4988: 4983: 4978: 4973: 4968: 4963: 4958: 4948: 4947: 4946: 4945: 4944: 4939: 4934: 4929: 4924: 4914: 4913: 4912: 4907: 4897: 4896: 4895: 4890: 4885: 4875: 4874: 4873: 4868: 4858: 4857: 4856: 4851: 4846: 4841: 4836: 4831: 4826: 4813: 4808: 4807: 4806: 4801: 4791: 4786: 4781: 4780: 4779: 4774: 4769: 4759: 4754: 4749: 4743: 4741: 4735: 4734: 4731: 4730: 4728: 4727: 4722: 4717: 4712: 4707: 4702: 4697: 4696: 4695: 4690: 4685: 4680: 4675: 4670: 4665: 4660: 4655: 4650: 4645: 4635: 4630: 4629: 4628: 4623: 4613: 4608: 4603: 4598: 4593: 4592: 4591: 4586: 4576: 4575: 4574: 4569: 4557: 4556: 4555: 4550: 4545: 4540: 4535: 4530: 4520: 4519: 4518: 4513: 4503: 4498: 4493: 4488: 4483: 4477: 4475: 4461: 4460: 4458: 4457: 4452: 4447: 4442: 4441: 4440: 4435: 4430: 4425: 4420: 4415: 4410: 4405: 4400: 4395: 4390: 4385: 4380: 4375: 4370: 4365: 4360: 4355: 4350: 4345: 4340: 4335: 4330: 4325: 4320: 4315: 4310: 4305: 4300: 4295: 4290: 4285: 4280: 4275: 4270: 4265: 4260: 4255: 4245: 4240: 4235: 4230: 4226:extended Hox: 4224: 4223: 4222: 4221: 4220: 4215: 4210: 4200: 4199: 4198: 4188: 4187: 4186: 4181: 4165: 4163: 4146: 4127: 4114: 4113: 4095: 4094: 4091: 4090: 4087: 4086: 4084: 4083: 4077: 4075: 4069: 4068: 4066: 4065: 4060: 4059: 4058: 4053: 4048: 4043: 4038: 4028: 4027: 4026: 4021: 4016: 4006: 4001: 3996: 3990: 3988: 3982: 3981: 3979: 3978: 3972: 3970: 3966: 3961: 3960: 3958: 3957: 3956: 3955: 3950: 3945: 3940: 3935: 3930: 3925: 3920: 3915: 3910: 3905: 3900: 3895: 3890: 3885: 3880: 3875: 3870: 3865: 3860: 3855: 3850: 3845: 3840: 3835: 3830: 3825: 3820: 3815: 3810: 3805: 3800: 3795: 3790: 3785: 3780: 3775: 3770: 3765: 3760: 3755: 3750: 3745: 3740: 3735: 3730: 3720: 3719: 3718: 3713: 3708: 3703: 3698: 3693: 3688: 3683: 3673: 3672: 3671: 3666: 3656: 3651: 3646: 3645: 3644: 3639: 3634: 3629: 3619: 3614: 3609: 3604: 3599: 3598: 3597: 3596: 3595: 3590: 3585: 3580: 3575: 3565: 3564: 3563: 3558: 3553: 3548: 3543: 3538: 3533: 3528: 3523: 3518: 3513: 3508: 3503: 3498: 3493: 3488: 3473: 3472: 3471: 3466: 3456: 3455: 3454: 3449: 3444: 3434: 3433: 3432: 3427: 3422: 3412: 3411: 3410: 3405: 3395: 3394: 3393: 3388: 3383: 3378: 3373: 3368: 3363: 3353: 3348: 3343: 3342: 3341: 3336: 3331: 3326: 3316: 3311: 3306: 3305: 3304: 3299: 3294: 3282: 3276: 3275: 3274: 3273: 3272: 3271: 3266: 3261: 3256: 3251: 3246: 3241: 3236: 3226: 3221: 3216: 3215: 3214: 3209: 3199: 3194: 3189: 3178: 3176: 3172: 3168: 3163: 3162: 3160: 3159: 3154: 3153: 3152: 3147: 3142: 3132: 3131: 3130: 3125: 3120: 3115: 3110: 3105: 3094: 3092: 3088: 3083: 3082: 3079: 3078: 3076: 3075: 3070: 3064: 3062: 3054: 3053: 3051: 3050: 3044: 3042: 3034: 3033: 3031: 3030: 3025: 3019: 3017: 3009: 3008: 3006: 3005: 3004: 3003: 2998: 2993: 2982: 2980: 2972: 2971: 2969: 2968: 2967: 2966: 2961: 2956: 2946: 2945: 2944: 2939: 2934: 2932:Glucocorticoid 2929: 2928: 2927: 2922: 2912: 2901: 2899: 2891: 2890: 2888: 2887: 2882: 2881: 2880: 2875: 2865: 2864: 2863: 2858: 2853: 2843: 2838: 2837: 2836: 2831: 2821: 2816: 2815: 2814: 2809: 2797: 2795: 2787: 2786: 2784: 2783: 2778: 2777: 2776: 2771: 2761: 2760: 2759: 2754: 2749: 2739: 2738: 2737: 2732: 2727: 2717: 2712: 2711: 2710: 2705: 2700: 2690: 2689: 2688: 2683: 2673: 2668: 2663: 2662: 2661: 2656: 2645: 2643: 2632: 2627: 2612: 2611: 2595: 2594: 2591: 2590: 2587: 2586: 2584: 2583: 2582: 2581: 2576: 2571: 2566: 2561: 2550: 2548: 2542: 2541: 2539: 2538: 2537: 2536: 2531: 2526: 2521: 2516: 2511: 2506: 2495: 2493: 2487: 2486: 2484: 2483: 2482: 2481: 2475: 2474: 2473: 2468: 2458: 2457: 2456: 2451: 2446: 2441: 2436: 2421: 2420: 2419: 2414: 2409: 2404: 2393: 2391: 2385: 2384: 2382: 2381: 2376: 2375: 2374: 2369: 2359: 2354: 2349: 2344: 2339: 2334: 2329: 2328: 2327: 2322: 2312: 2306: 2304: 2295: 2294: 2291: 2290: 2288: 2287: 2281: 2279: 2271: 2270: 2268: 2267: 2266: 2265: 2260: 2255: 2245: 2244: 2243: 2238: 2233: 2228: 2223: 2218: 2213: 2202: 2200: 2194: 2193: 2191: 2190: 2189: 2188: 2183: 2178: 2173: 2163: 2158: 2157: 2156: 2151: 2146: 2135: 2133: 2127: 2126: 2124: 2123: 2122: 2121: 2116: 2106: 2105: 2104: 2099: 2094: 2089: 2079: 2078: 2077: 2072: 2067: 2059: 2058: 2057: 2052: 2047: 2037: 2032: 2031: 2030: 2025: 2015: 2010: 2004: 2002: 1991: 1990: 1988: 1987: 1982: 1977: 1976: 1975: 1970: 1965: 1955: 1949: 1947: 1941: 1940: 1938: 1937: 1932: 1931: 1930: 1929: 1928: 1923: 1913: 1903: 1902: 1901: 1896: 1886: 1885: 1884: 1879: 1869: 1868: 1867: 1862: 1857: 1847: 1846: 1845: 1840: 1830: 1829: 1828: 1823: 1818: 1813: 1803: 1798: 1797: 1796: 1791: 1781: 1776: 1775: 1774: 1769: 1758: 1756: 1747: 1736: 1735: 1733: 1732: 1727: 1726: 1725: 1720: 1715: 1705: 1700: 1695: 1694: 1693: 1688: 1683: 1678: 1668: 1667: 1666: 1661: 1656: 1651: 1641: 1636: 1631: 1626: 1621: 1616: 1611: 1610: 1609: 1604: 1599: 1589: 1588: 1587: 1582: 1577: 1572: 1567: 1562: 1552: 1547: 1542: 1541: 1540: 1535: 1525: 1524: 1523: 1518: 1513: 1508: 1503: 1498: 1493: 1488: 1478: 1477: 1476: 1471: 1466: 1461: 1456: 1451: 1446: 1441: 1430: 1428: 1421:leucine zipper 1410: 1409: 1397: 1396: 1385: 1384: 1377: 1370: 1362: 1355: 1354: 1311: 1276: 1238: 1210:(15): 4292–8. 1194: 1192: 1189: 1186: 1185: 1126: 1059: 1000: 963:(4): 527–543. 943: 914:(4): 1036–47. 894: 842: 829: 810: 781:(15): 4292–8. 758: 723:(1): 231–286. 698: 644: 621: 593: 526: 495:(3): 1245–65. 465: 464: 462: 459: 449: 443: 426: 420: 397:Audrey Stevens 388: 385: 379: 376: 373: 372: 369: 366: 362: 361: 358: 355: 349: 348: 345: 342: 336: 335: 332: 329: 325: 324: 321: 315: 309: 308: 305: 302: 275: 269: 233: 230: 172:membrane-bound 134: 131: 128: 127: 42: 40: 33: 26: 9: 6: 4: 3: 2: 6824: 6813: 6810: 6809: 6807: 6794: 6793: 6786: 6772: 6768: 6765: 6761: 6758: 6756: 6753: 6751: 6748: 6747: 6746: 6743: 6741: 6738: 6734: 6731: 6729: 6726: 6724: 6721: 6720: 6719: 6716: 6712: 6709: 6707: 6704: 6703: 6702: 6699: 6697: 6694: 6690: 6687: 6685: 6682: 6680: 6677: 6675: 6672: 6670: 6667: 6665: 6662: 6661: 6660: 6657: 6656: 6654: 6652: 6648: 6642: 6639: 6637: 6634: 6632: 6629: 6628: 6626: 6624: 6621: 6618: 6615: 6612: 6608: 6602: 6599: 6597: 6594: 6592: 6589: 6588: 6586: 6584: 6583:Pocket domain 6581: 6577: 6571: 6568: 6564: 6561: 6559: 6556: 6555: 6554: 6551: 6550: 6548: 6546: 6545:(0.2) HMGI(Y) 6542: 6538: 6534: 6529: 6525: 6509: 6506: 6504: 6501: 6499: 6496: 6494: 6491: 6489: 6486: 6484: 6481: 6480: 6479: 6476: 6475: 6473: 6471: 6467: 6461: 6458: 6456: 6453: 6452: 6450: 6448: 6444: 6438: 6435: 6434: 6432: 6430: 6426: 6418: 6415: 6413: 6410: 6408: 6405: 6403: 6400: 6399: 6398: 6395: 6391: 6388: 6384: 6381: 6379: 6376: 6374: 6371: 6370: 6369: 6366: 6365: 6364: 6361: 6359: 6356: 6354: 6351: 6347: 6344: 6342: 6339: 6337: 6334: 6332: 6329: 6327: 6324: 6322: 6319: 6317: 6314: 6312: 6309: 6307: 6304: 6302: 6299: 6297: 6294: 6292: 6289: 6287: 6284: 6282: 6279: 6277: 6274: 6272: 6269: 6268: 6267: 6264: 6260: 6257: 6255: 6252: 6251: 6250: 6247: 6243: 6240: 6238: 6235: 6233: 6230: 6228: 6225: 6224: 6223: 6220: 6216: 6213: 6211: 6208: 6206: 6203: 6201: 6198: 6197: 6196: 6193: 6191: 6188: 6187: 6185: 6183: 6180: 6176: 6170: 6167: 6165: 6162: 6161: 6159: 6157: 6154: 6150: 6144: 6141: 6137: 6134: 6132: 6129: 6127: 6124: 6122: 6119: 6118: 6117: 6114: 6113: 6111: 6109: 6106: 6102: 6096: 6093: 6089: 6086: 6084: 6081: 6079: 6076: 6074: 6071: 6069: 6066: 6064: 6061: 6059: 6056: 6054: 6051: 6049: 6046: 6044: 6041: 6040: 6039: 6036: 6032: 6029: 6027: 6024: 6022: 6019: 6018: 6017: 6014: 6013: 6011: 6009: 6005: 5997: 5994: 5992: 5989: 5987: 5984: 5982: 5979: 5977: 5974: 5972: 5969: 5968: 5967: 5964: 5963: 5961: 5959: 5956: 5952: 5944: 5941: 5939: 5936: 5934: 5931: 5929: 5926: 5924: 5921: 5920: 5919: 5916: 5912: 5909: 5907: 5904: 5902: 5899: 5897: 5894: 5892: 5889: 5888: 5887: 5884: 5883: 5881: 5879: 5876: 5872: 5868: 5864: 5858: 5854: 5838: 5835: 5833: 5830: 5828: 5825: 5823: 5820: 5819: 5818: 5815: 5814: 5812: 5810: 5806: 5800: 5797: 5795: 5792: 5788: 5785: 5783: 5780: 5778: 5775: 5773: 5770: 5768: 5765: 5763: 5760: 5758: 5755: 5753: 5750: 5749: 5748: 5745: 5743: 5740: 5736: 5733: 5731: 5728: 5726: 5723: 5721: 5718: 5717: 5716: 5713: 5709: 5706: 5704: 5701: 5699: 5696: 5694: 5691: 5690: 5689: 5686: 5684: 5681: 5677: 5674: 5672: 5669: 5667: 5664: 5663: 5662: 5659: 5657: 5654: 5650: 5647: 5645: 5642: 5640: 5637: 5636: 5635: 5632: 5631: 5629: 5627: 5623: 5615: 5612: 5610: 5607: 5605: 5602: 5601: 5600: 5599: 5595: 5594: 5592: 5590: 5587: 5583: 5575: 5572: 5570: 5567: 5565: 5562: 5560: 5557: 5555: 5552: 5550: 5547: 5545: 5542: 5540: 5537: 5535: 5532: 5530: 5527: 5525: 5522: 5520: 5517: 5515: 5512: 5510: 5507: 5505: 5502: 5500: 5497: 5495: 5492: 5490: 5487: 5485: 5482: 5480: 5477: 5475: 5472: 5470: 5467: 5465: 5462: 5460: 5457: 5455: 5452: 5450: 5447: 5445: 5442: 5440: 5437: 5435: 5432: 5430: 5427: 5425: 5422: 5420: 5417: 5415: 5412: 5410: 5407: 5405: 5402: 5400: 5397: 5395: 5392: 5390: 5387: 5385: 5382: 5380: 5377: 5375: 5372: 5370: 5367: 5365: 5362: 5360: 5357: 5355: 5352: 5350: 5347: 5345: 5342: 5340: 5337: 5335: 5332: 5331: 5330: 5327: 5323: 5320: 5318: 5315: 5313: 5310: 5308: 5305: 5303: 5300: 5299: 5298: 5295: 5294: 5292: 5290: 5286: 5283: 5279: 5269: 5266: 5264: 5261: 5259: 5256: 5255: 5254: 5251: 5247: 5244: 5242: 5239: 5238: 5237: 5234: 5232: 5229: 5227: 5224: 5223: 5222: 5219: 5217: 5214: 5212: 5209: 5207: 5204: 5202: 5199: 5197: 5194: 5190: 5187: 5185: 5182: 5181: 5180: 5177: 5175: 5172: 5168: 5165: 5163: 5160: 5159: 5157: 5153: 5150: 5148: 5145: 5143: 5140: 5138: 5135: 5133: 5130: 5128: 5125: 5123: 5120: 5118: 5115: 5113: 5110: 5109: 5108: 5105: 5104: 5102: 5100: 5096: 5084: 5081: 5079: 5076: 5075: 5074: 5071: 5069: 5066: 5062: 5059: 5057: 5054: 5052: 5049: 5047: 5044: 5042: 5039: 5037: 5033: 5030: 5028: 5025: 5023: 5020: 5018: 5014: 5011: 5009: 5006: 5005: 5004: 5001: 4997: 4994: 4992: 4989: 4987: 4984: 4982: 4979: 4977: 4974: 4972: 4969: 4967: 4964: 4962: 4959: 4957: 4954: 4953: 4952: 4949: 4943: 4940: 4938: 4935: 4933: 4930: 4928: 4925: 4923: 4920: 4919: 4918: 4915: 4911: 4908: 4906: 4903: 4902: 4901: 4898: 4894: 4891: 4889: 4886: 4884: 4881: 4880: 4879: 4876: 4872: 4869: 4867: 4864: 4863: 4862: 4859: 4855: 4852: 4850: 4847: 4845: 4842: 4840: 4837: 4835: 4832: 4830: 4827: 4825: 4822: 4821: 4820: 4817: 4816: 4814: 4812: 4809: 4805: 4802: 4800: 4797: 4796: 4795: 4792: 4790: 4787: 4785: 4782: 4778: 4775: 4773: 4770: 4768: 4765: 4764: 4763: 4760: 4758: 4755: 4753: 4750: 4748: 4745: 4744: 4742: 4736: 4726: 4723: 4721: 4718: 4716: 4713: 4711: 4708: 4706: 4703: 4701: 4698: 4694: 4691: 4689: 4686: 4684: 4681: 4679: 4676: 4674: 4671: 4669: 4666: 4664: 4661: 4659: 4656: 4654: 4651: 4649: 4646: 4644: 4641: 4640: 4639: 4636: 4634: 4631: 4627: 4624: 4622: 4619: 4618: 4617: 4614: 4612: 4609: 4607: 4604: 4602: 4599: 4597: 4594: 4590: 4587: 4585: 4582: 4581: 4580: 4577: 4573: 4570: 4568: 4565: 4564: 4563: 4562: 4558: 4554: 4551: 4549: 4546: 4544: 4541: 4539: 4536: 4534: 4531: 4529: 4526: 4525: 4524: 4521: 4517: 4514: 4512: 4509: 4508: 4507: 4504: 4502: 4499: 4497: 4494: 4492: 4489: 4487: 4484: 4482: 4479: 4478: 4476: 4473: 4467: 4462: 4456: 4453: 4451: 4448: 4446: 4443: 4439: 4436: 4434: 4431: 4429: 4426: 4424: 4421: 4419: 4416: 4414: 4411: 4409: 4406: 4404: 4401: 4399: 4396: 4394: 4391: 4389: 4386: 4384: 4381: 4379: 4376: 4374: 4371: 4369: 4366: 4364: 4361: 4359: 4356: 4354: 4351: 4349: 4346: 4344: 4341: 4339: 4336: 4334: 4331: 4329: 4326: 4324: 4321: 4319: 4316: 4314: 4311: 4309: 4306: 4304: 4301: 4299: 4296: 4294: 4291: 4289: 4286: 4284: 4281: 4279: 4276: 4274: 4271: 4269: 4266: 4264: 4261: 4259: 4256: 4254: 4251: 4250: 4249: 4246: 4244: 4241: 4239: 4236: 4234: 4231: 4229: 4225: 4219: 4216: 4214: 4211: 4209: 4206: 4205: 4204: 4201: 4197: 4194: 4193: 4192: 4189: 4185: 4182: 4180: 4177: 4176: 4175: 4172: 4171: 4170: 4167: 4166: 4164: 4161: 4155: 4150: 4147: 4144: 4138: 4137: 4131: 4128: 4126: 4123: 4119: 4115: 4111: 4108: 4105: 4100: 4096: 4082: 4079: 4078: 4076: 4074: 4070: 4064: 4061: 4057: 4054: 4052: 4049: 4047: 4044: 4042: 4039: 4037: 4034: 4033: 4032: 4029: 4025: 4022: 4020: 4017: 4015: 4012: 4011: 4010: 4007: 4005: 4002: 4000: 3997: 3995: 3992: 3991: 3989: 3987: 3983: 3977: 3974: 3973: 3971: 3969: 3962: 3954: 3951: 3949: 3946: 3944: 3941: 3939: 3936: 3934: 3931: 3929: 3926: 3924: 3921: 3919: 3916: 3914: 3911: 3909: 3906: 3904: 3901: 3899: 3896: 3894: 3891: 3889: 3886: 3884: 3881: 3879: 3876: 3874: 3871: 3869: 3866: 3864: 3861: 3859: 3856: 3854: 3851: 3849: 3846: 3844: 3841: 3839: 3836: 3834: 3831: 3829: 3826: 3824: 3821: 3819: 3816: 3814: 3811: 3809: 3806: 3804: 3801: 3799: 3796: 3794: 3791: 3789: 3786: 3784: 3781: 3779: 3776: 3774: 3771: 3769: 3766: 3764: 3761: 3759: 3756: 3754: 3751: 3749: 3746: 3744: 3741: 3739: 3736: 3734: 3731: 3729: 3726: 3725: 3724: 3721: 3717: 3714: 3712: 3709: 3707: 3704: 3702: 3699: 3697: 3694: 3692: 3689: 3687: 3684: 3682: 3679: 3678: 3677: 3674: 3670: 3667: 3665: 3662: 3661: 3660: 3657: 3655: 3652: 3650: 3647: 3643: 3640: 3638: 3635: 3633: 3630: 3628: 3625: 3624: 3623: 3620: 3618: 3615: 3613: 3610: 3608: 3605: 3603: 3600: 3594: 3591: 3589: 3586: 3584: 3581: 3579: 3576: 3574: 3571: 3570: 3569: 3566: 3562: 3559: 3557: 3554: 3552: 3549: 3547: 3544: 3542: 3539: 3537: 3534: 3532: 3529: 3527: 3524: 3522: 3519: 3517: 3514: 3512: 3509: 3507: 3504: 3502: 3499: 3497: 3494: 3492: 3489: 3487: 3484: 3483: 3482: 3479: 3478: 3477: 3476:Sp/KLF family 3474: 3470: 3467: 3465: 3462: 3461: 3460: 3457: 3453: 3450: 3448: 3445: 3443: 3440: 3439: 3438: 3435: 3431: 3428: 3426: 3423: 3421: 3418: 3417: 3416: 3413: 3409: 3406: 3404: 3401: 3400: 3399: 3396: 3392: 3389: 3387: 3384: 3382: 3379: 3377: 3374: 3372: 3369: 3367: 3364: 3362: 3359: 3358: 3357: 3354: 3352: 3349: 3347: 3344: 3340: 3337: 3335: 3332: 3330: 3327: 3325: 3322: 3321: 3320: 3317: 3315: 3312: 3310: 3307: 3303: 3300: 3298: 3295: 3293: 3290: 3289: 3288: 3287: 3283: 3281: 3278: 3277: 3270: 3267: 3265: 3262: 3260: 3257: 3255: 3252: 3250: 3247: 3245: 3242: 3240: 3237: 3235: 3232: 3231: 3230: 3227: 3225: 3222: 3220: 3217: 3213: 3210: 3208: 3205: 3204: 3203: 3200: 3198: 3195: 3193: 3190: 3188: 3185: 3184: 3183: 3180: 3179: 3177: 3175: 3164: 3158: 3155: 3151: 3148: 3146: 3143: 3141: 3138: 3137: 3136: 3133: 3129: 3126: 3124: 3121: 3119: 3116: 3114: 3111: 3109: 3106: 3104: 3101: 3100: 3099: 3096: 3095: 3093: 3091: 3084: 3074: 3071: 3069: 3066: 3065: 3063: 3060: 3055: 3049: 3046: 3045: 3043: 3040: 3035: 3029: 3026: 3024: 3021: 3020: 3018: 3015: 3010: 3002: 2999: 2997: 2994: 2992: 2989: 2988: 2987: 2984: 2983: 2981: 2978: 2973: 2965: 2962: 2960: 2957: 2955: 2952: 2951: 2950: 2947: 2943: 2940: 2938: 2935: 2933: 2930: 2926: 2923: 2921: 2918: 2917: 2916: 2913: 2911: 2908: 2907: 2906: 2903: 2902: 2900: 2897: 2892: 2886: 2883: 2879: 2876: 2874: 2871: 2870: 2869: 2866: 2862: 2859: 2857: 2854: 2852: 2849: 2848: 2847: 2844: 2842: 2839: 2835: 2832: 2830: 2827: 2826: 2825: 2822: 2820: 2817: 2813: 2810: 2808: 2804: 2803: 2802: 2799: 2798: 2796: 2793: 2788: 2782: 2779: 2775: 2772: 2770: 2767: 2766: 2765: 2762: 2758: 2755: 2753: 2750: 2748: 2745: 2744: 2743: 2740: 2736: 2733: 2731: 2728: 2726: 2723: 2722: 2721: 2718: 2716: 2713: 2709: 2706: 2704: 2701: 2699: 2696: 2695: 2694: 2691: 2687: 2684: 2682: 2679: 2678: 2677: 2674: 2672: 2669: 2667: 2664: 2660: 2657: 2655: 2652: 2651: 2650: 2647: 2646: 2644: 2641: 2636: 2633: 2631: 2624: 2621: 2617: 2613: 2608: 2605: 2600: 2596: 2580: 2577: 2575: 2572: 2570: 2567: 2565: 2562: 2560: 2557: 2556: 2555: 2552: 2551: 2549: 2547: 2543: 2535: 2532: 2530: 2527: 2525: 2522: 2520: 2517: 2515: 2512: 2510: 2507: 2505: 2502: 2501: 2500: 2497: 2496: 2494: 2492: 2488: 2479: 2476: 2472: 2469: 2467: 2464: 2463: 2462: 2459: 2455: 2452: 2450: 2447: 2445: 2442: 2440: 2437: 2435: 2432: 2431: 2430: 2427: 2426: 2425: 2422: 2418: 2415: 2413: 2410: 2408: 2405: 2403: 2400: 2399: 2398: 2395: 2394: 2392: 2390: 2386: 2380: 2377: 2373: 2370: 2368: 2365: 2364: 2363: 2360: 2358: 2355: 2353: 2350: 2348: 2345: 2343: 2340: 2338: 2335: 2333: 2330: 2326: 2323: 2321: 2318: 2317: 2316: 2313: 2311: 2308: 2307: 2305: 2303: 2300: 2296: 2286: 2283: 2282: 2280: 2272: 2264: 2261: 2259: 2256: 2254: 2251: 2250: 2249: 2246: 2242: 2239: 2237: 2234: 2232: 2229: 2227: 2224: 2222: 2219: 2217: 2214: 2212: 2209: 2208: 2207: 2204: 2203: 2201: 2195: 2187: 2184: 2182: 2179: 2177: 2174: 2172: 2169: 2168: 2167: 2164: 2162: 2159: 2155: 2152: 2150: 2147: 2145: 2142: 2141: 2140: 2137: 2136: 2134: 2128: 2120: 2117: 2115: 2112: 2111: 2110: 2107: 2103: 2100: 2098: 2095: 2093: 2090: 2088: 2085: 2084: 2083: 2080: 2076: 2073: 2071: 2068: 2066: 2063: 2062: 2060: 2056: 2053: 2051: 2048: 2046: 2043: 2042: 2041: 2038: 2036: 2033: 2029: 2026: 2024: 2021: 2020: 2019: 2016: 2014: 2011: 2009: 2006: 2005: 2003: 2000: 1992: 1986: 1983: 1981: 1978: 1974: 1971: 1969: 1966: 1964: 1961: 1960: 1959: 1956: 1954: 1951: 1950: 1948: 1942: 1936: 1933: 1927: 1924: 1922: 1919: 1918: 1917: 1914: 1912: 1909: 1908: 1907: 1904: 1900: 1897: 1895: 1892: 1891: 1890: 1887: 1883: 1880: 1878: 1875: 1874: 1873: 1870: 1866: 1863: 1861: 1858: 1856: 1853: 1852: 1851: 1848: 1844: 1841: 1839: 1836: 1835: 1834: 1831: 1827: 1824: 1822: 1819: 1817: 1814: 1812: 1809: 1808: 1807: 1804: 1802: 1799: 1795: 1792: 1790: 1787: 1786: 1785: 1782: 1780: 1777: 1773: 1770: 1768: 1765: 1764: 1763: 1760: 1759: 1757: 1751: 1748: 1745: 1741: 1737: 1731: 1728: 1724: 1721: 1719: 1716: 1714: 1711: 1710: 1709: 1706: 1704: 1701: 1699: 1696: 1692: 1689: 1687: 1684: 1682: 1679: 1677: 1674: 1673: 1672: 1669: 1665: 1662: 1660: 1657: 1655: 1652: 1650: 1647: 1646: 1645: 1642: 1640: 1637: 1635: 1632: 1630: 1627: 1625: 1622: 1620: 1617: 1615: 1612: 1608: 1605: 1603: 1600: 1598: 1595: 1594: 1593: 1590: 1586: 1583: 1581: 1578: 1576: 1573: 1571: 1568: 1566: 1563: 1561: 1558: 1557: 1556: 1553: 1551: 1548: 1546: 1543: 1539: 1536: 1534: 1531: 1530: 1529: 1526: 1522: 1519: 1517: 1514: 1512: 1509: 1507: 1504: 1502: 1499: 1497: 1494: 1492: 1489: 1487: 1484: 1483: 1482: 1479: 1475: 1472: 1470: 1467: 1465: 1462: 1460: 1457: 1455: 1452: 1450: 1447: 1445: 1442: 1440: 1437: 1436: 1435: 1432: 1431: 1429: 1426: 1422: 1419: 1415: 1411: 1407: 1402: 1398: 1394: 1390: 1383: 1378: 1376: 1371: 1369: 1364: 1363: 1360: 1351: 1347: 1342: 1337: 1333: 1329: 1325: 1321: 1317: 1312: 1308: 1304: 1299: 1294: 1291:(2): 135–41. 1290: 1286: 1282: 1277: 1273: 1269: 1265: 1261: 1257: 1253: 1249: 1245: 1239: 1235: 1231: 1226: 1221: 1217: 1213: 1209: 1205: 1201: 1196: 1195: 1181: 1177: 1172: 1167: 1163: 1159: 1154: 1149: 1145: 1141: 1137: 1130: 1122: 1118: 1113: 1108: 1104: 1100: 1095: 1090: 1086: 1082: 1078: 1074: 1070: 1063: 1055: 1051: 1046: 1041: 1037: 1033: 1028: 1023: 1019: 1015: 1011: 1004: 996: 992: 987: 982: 978: 974: 970: 966: 962: 958: 954: 947: 939: 935: 931: 927: 922: 917: 913: 909: 905: 898: 890: 886: 881: 876: 872: 868: 864: 860: 856: 849: 847: 832: 830:9780123785947 826: 822: 821: 814: 806: 802: 797: 792: 788: 784: 780: 776: 772: 765: 763: 754: 750: 746: 742: 738: 734: 730: 726: 722: 718: 714: 707: 705: 703: 694: 690: 685: 680: 676: 672: 669:(6): 378–87. 668: 664: 660: 653: 651: 649: 640: 636: 632: 628: 624: 622:9780120277469 618: 614: 610: 606: 605: 597: 589: 585: 580: 575: 571: 567: 562: 557: 553: 549: 546:(5): e19235. 545: 541: 537: 530: 522: 518: 513: 508: 503: 498: 494: 490: 486: 479: 477: 475: 473: 471: 466: 458: 455: 448: 442: 439: 434: 433: 425: 419: 416: 414: 410: 403: 398: 393: 384: 370: 367: 364: 363: 359: 356: 354: 351: 350: 346: 343: 341: 338: 337: 333: 330: 327: 326: 322: 320: 316: 314: 311: 310: 306: 304:Sigma Effect 303: 301:Sigma factor 300: 299: 296: 294: 290: 286: 285:transcription 282: 281: 274: 268: 266: 261: 257: 254: 250: 246: 241: 239: 229: 225: 223: 218: 216: 212: 208: 204: 200: 199:Sigma factors 193: 188: 184: 182: 178: 173: 169: 165: 161: 160: 155: 154: 148: 144: 143:sigma factors 141:that bind to 140: 124: 121: 113: 102: 99: 95: 92: 88: 85: 81: 78: 74: 71: –  70: 66: 65:Find sources: 59: 55: 49: 48: 43:This article 41: 37: 32: 31: 19: 6789: 6744: 6700: 6658: 6650: 6622: 6616: 6610: 6579: 6544: 6532: 6469: 6446: 6428: 6396: 6367: 6248: 6178: 6152: 6104: 6007: 5954: 5874: 5862: 5816: 5808: 5714: 5660: 5633: 5625: 5596: 5585: 5329:FOX proteins 5289:winged helix 5281: 5252: 5235: 5178: 5098: 5072: 4950: 4916: 4899: 4877: 4860: 4793: 4761: 4615: 4578: 4559: 4505: 4471: 4465: 4159: 4153: 4142: 4136:Antennapedia 4134: 4121: 4109: 4103: 4072: 4030: 4008: 3985: 3964: 3722: 3675: 3621: 3567: 3480: 3458: 3436: 3414: 3397: 3355: 3284: 3166: 3134: 3086: 3058: 3038: 3013: 2976: 2942:Progesterone 2895: 2791: 2639: 2625: 2619: 2603: 2545: 2498: 2490: 2388: 2298: 2247: 2205: 2165: 2138: 2108: 2081: 1915: 1905: 1888: 1871: 1783: 1739: 1707: 1670: 1527: 1417: 1405: 1323: 1319: 1288: 1284: 1247: 1243: 1207: 1203: 1143: 1139: 1129: 1076: 1072: 1062: 1017: 1013: 1003: 960: 956: 946: 911: 907: 897: 862: 858: 834:. Retrieved 819: 813: 778: 774: 720: 716: 666: 662: 603: 596: 543: 539: 529: 492: 489:Biomolecules 488: 453: 451: 446: 430: 428: 423: 417: 412: 407: 381: 288: 279: 277: 272: 262: 258: 242: 235: 226: 219: 197: 157: 151: 145:and inhibit 136: 133:Introduction 116: 107: 97: 90: 83: 76: 64: 52:Please help 47:verification 44: 6470:(4.11) Runt 4125:Homeodomain 3723:zinc finger 3059:subfamily 0 3039:subfamily 6 3014:subfamily 5 2977:subfamily 4 2896:subfamily 3 2792:subfamily 2 2640:subfamily 1 2607:Zinc finger 1850:Neurogenins 1418:(1.1) Basic 249:phosphatase 238:proteolysis 181:cell growth 168:cytoplasmic 5003:POU domain 4143:ANTP class 4073:(2.6) WRKY 3356:GLI family 2491:(1.5) RF-X 2389:(1.4) NF-1 836:2023-12-02 461:References 159:Salmonella 80:newspapers 6790:see also 6631:Apetala 2 5285:Fork head 3965:(2.4) Cys 3167:(2.3) Cys 1899:Scleraxis 1162:1664-302X 1103:0027-8424 1036:1664-302X 977:1092-2172 737:0066-4227 631:0065-2911 570:1932-6203 232:Mechanism 177:flagellum 110:June 2008 6806:Category 6108:MADS box 4248:Homeobox 4160:Hox-like 4154:protoHOX 2915:Estrogen 2910:Androgen 2764:Rev-ErbA 2302:bHLH-ZIP 2277:bHLH-COE 1816:Myogenin 1350:20817765 1307:10322161 1272:41958324 1234:10428967 1180:33042030 1146:: 1761. 1054:33042030 1020:: 1761. 995:16339734 930:11251822 889:20817765 805:10428967 753:39757445 693:24396271 639:12073657 588:21573101 540:PLOS ONE 521:26131973 445:RsbW in 139:proteins 6508:RUNX1T1 6488:CBFA2T3 6483:CBFA2T2 6363:TCF/LEF 4472:NK-like 4466:metaHOX 4169:ParaHox 4110:domains 2801:COUP-TF 2275:Group F 2198:Group E 2131:Group D 1995:Group C 1945:Group B 1889:Paraxis 1754:Group A 1341:2953704 1264:1453955 1225:1171505 1171:7522486 1121:8460143 1081:Bibcode 1045:7522486 986:1306804 938:5957348 880:2953704 796:1171505 745:9891799 684:3861889 579:3089606 548:Bibcode 512:4598750 289:E. coli 280:E. coli 94:scholar 5221:Bicoid 4486:BARHL2 4481:BARHL1 4063:JMJD1B 3976:HIVEP1 2461:I-SMAD 2429:R-SMAD 2347:MLXIPL 2102:Period 2028:ARNTL2 1833:NeuroD 1348:  1338:  1305:  1270:  1262:  1232:  1222:  1178:  1168:  1160:  1119:  1109:  1101:  1052:  1042:  1034:  993:  983:  975:  936:  928:  887:  877:  827:  803:  793:  751:  743:  735:  691:  681:  637:  629:  619:  586:  576:  568:  519:  509:  96:  89:  82:  75:  67:  6771:Sigma 6636:EREBP 6620:EREBP 6611:(0.5) 6580:(0.3) 6503:RUNX3 6498:RUNX2 6493:RUNX1 6437:TFCP2 6358:SSRP1 6179:(4.7) 6169:TBPL1 6153:(4.6) 6105:(4.4) 5955:(4.2) 5896:NFKB2 5891:NFKB1 5886:NF-κB 5875:(4.1) 5799:MYBL2 5586:(3.4) 5282:(3.3) 5231:BICD2 5206:SHOX2 5174:PROP1 5158:PRRX 5068:SATB2 5013:BRN-3 5008:PIT-1 4900:PKNOX 4815:TALE 4811:NOBOX 4784:HESX1 4757:CUTL1 4739:other 4633:NANOG 4496:BARX2 4491:BARX1 4243:MEOX2 4238:MEOX1 4122:(3.1) 4031:JARID 4004:GRLF1 3999:DIDO1 3659:Zbtb7 3649:TSHZ3 3617:PRDM9 3415:HIVEP 3280:ATBF1 3234:TFIIH 3219:TFIIF 3202:TFIIE 3197:TFIID 3192:TFIIB 3187:TFIIA 3157:TRPS1 3023:LRH-1 3001:NURR1 2991:NGFIB 2819:Ear-2 2620:(2.1) 2362:SREBP 2299:(1.3) 2061:NPAS 2050:EPAS1 2035:CLOCK 2023:ARNTL 1997:bHLH- 1973:n-Myc 1968:l-Myc 1963:c-Myc 1953:FIGLA 1935:Twist 1894:TCF15 1801:MESP2 1779:ATOH1 1772:ASCL2 1767:ASCL1 1698:NFIL3 1629:GABPA 1624:DDIT3 1555:C/EBP 1550:BLZF1 1511:c-Jun 1501:FOSL2 1496:FOSL1 1486:c-Fos 1268:S2CID 1112:46080 934:S2CID 749:S2CID 452:When 371:FecR 360:RseA 347:FIgM 334:Dnak 323:RssB 101:JSTOR 87:books 6740:MNDA 6659:ARID 6614:AP-2 6601:RBL2 6596:RBL1 6570:HBP1 6553:HMGA 6460:YBX1 6455:CSDA 6390:LEF1 6222:HMGN 6195:HMGB 6116:Mef2 6095:MYRF 6083:TBR2 6078:TBR1 6026:TP63 5966:STAT 5958:STAT 5918:NFAT 5911:RELB 5906:RELA 5861:(4) 5742:FLI1 5708:SPIB 5409:D4L6 5404:D4L5 5399:D4L4 5394:D4L3 5389:D4L1 5253:PITX 5216:VSX2 5211:VSX1 5201:SHOX 5179:PHOX 4861:MEIS 4789:HOPX 4725:VAX2 4720:VAX1 4715:TLX3 4710:TLX2 4705:TLX1 4700:NATO 4683:HMX3 4678:HMX2 4673:HMX1 4611:LBX2 4606:LBX1 4596:HHEX 4455:MNX1 4450:GBX2 4445:GBX1 4233:Evx2 4228:Evx1 4196:PDX1 4191:Xlox 4081:WRKY 3994:AIRE 3953:804A 3676:ZBTB 3622:SALL 3612:OSR1 3607:MYT1 3602:MTF1 3437:IKZF 3376:REST 3351:GFI1 3346:ERV3 3314:E4F1 3309:CTCF 3098:GATA 3068:DAX1 3048:GCNF 2996:NOR1 2824:HNF4 2693:PPAR 2626:(Cys 2554:AP-2 2424:SMAD 2379:USF1 2352:MXI1 2332:MITF 2325:MXD3 2320:MXD1 2310:AP-4 2285:EBF1 2161:Pho4 2139:BHLH 2018:ARNT 2013:AHRR 1985:TCF4 1980:MXD4 1911:LYL1 1872:OLIG 1826:MYF6 1821:MYF5 1811:MyoD 1784:HAND 1762:AS-C 1744:bHLH 1730:XBP1 1634:GCN4 1614:CREM 1592:CREB 1545:BATF 1528:BACH 1521:JunD 1516:JUNB 1506:JDP2 1491:FOSB 1481:AP-1 1439:AATF 1425:bZIP 1391:and 1346:PMID 1303:PMID 1260:PMID 1230:PMID 1176:PMID 1158:ISSN 1117:PMID 1099:ISSN 1050:PMID 1032:ISSN 991:PMID 973:ISSN 926:PMID 885:PMID 825:ISBN 801:PMID 741:PMID 733:ISSN 689:PMID 635:PMID 627:ISSN 617:ISBN 584:PMID 566:ISSN 517:PMID 438:RNAP 402:1jr5 263:The 207:RNAP 201:are 156:and 73:news 6767:Rho 6745:NFY 6718:MLL 6701:IFI 6696:CAP 6478:CBF 6397:TOX 6368:TCF 6353:SRY 6266:SOX 6249:HNF 6190:BBX 6164:TBP 6143:SRF 6088:TFT 6038:TBX 6031:p73 6021:p53 5901:REL 5794:MYB 5715:ETV 5703:ERG 5688:ETS 5683:ERF 5661:ELK 5656:EGF 5634:ELF 5598:HSF 5297:E2F 5236:OTX 5226:GSC 5196:RAX 5107:PAX 5073:ZEB 5046:3/4 4996:21A 4951:PHF 4917:SIX 4878:PBX 4854:MKX 4819:IRX 4794:LMX 4762:FHL 4752:CRX 4747:ARX 4693:6-2 4688:6-1 4668:3-2 4663:3-1 4658:2-5 4653:2-3 4648:2-2 4643:2-1 4638:NKX 4616:MSX 4601:HLX 4561:EMX 4523:DLX 4506:DBX 4501:BSX 4438:D13 4433:D12 4428:D11 4423:D10 4393:C13 4388:C12 4383:C11 4378:C10 4348:B13 4298:A13 4293:A11 4288:A10 4203:Cdx 4174:Gsx 4104:(3) 4009:ING 3948:655 3943:649 3938:644 3933:638 3928:593 3923:471 3918:452 3913:451 3908:423 3903:384 3898:366 3893:365 3888:350 3883:346 3878:330 3873:318 3868:300 3863:281 3858:268 3853:267 3848:259 3843:239 3838:238 3833:219 3828:217 3823:202 3818:165 3813:148 3808:146 3803:143 3763:33B 3654:WT1 3481:KLF 3459:ILF 3398:HIC 3391:YY1 3319:EGR 3302:11B 3297:11A 3286:BCL 3269:3C2 3264:3C1 3171:His 3135:MTA 3073:SHP 3028:SF1 2986:NUR 2885:TLX 2846:RXR 2841:PNR 2781:VDR 2742:ROR 2720:RAR 2715:PXR 2703:β/δ 2676:LXR 2671:FXR 2666:CAR 2604:(2) 2534:ANK 2499:RFX 2397:NFI 2357:Myc 2342:MLX 2337:MNT 2315:MAX 2248:HEY 2206:HES 2109:SIM 2082:PER 2040:HIF 2008:AhR 1999:PAS 1958:Myc 1916:TAL 1906:SLC 1708:NRF 1703:NRL 1671:NFE 1644:MAF 1639:HLF 1619:DBP 1336:PMC 1328:doi 1324:192 1293:doi 1252:doi 1220:PMC 1212:doi 1166:PMC 1148:doi 1107:PMC 1089:doi 1040:PMC 1022:doi 981:PMC 965:doi 916:doi 875:PMC 867:doi 863:192 791:PMC 783:doi 725:doi 679:PMC 671:doi 609:doi 574:PMC 556:doi 507:PMC 497:doi 56:by 6808:: 6733:T1 6711:35 6706:16 6689:4A 6684:3B 6679:3A 6669:1B 6664:1A 6641:B3 6591:Rb 6346:21 6341:18 6336:15 6331:14 6326:13 6321:12 6316:11 6311:10 6259:1B 6254:1A 6073:22 6068:21 6063:19 5938:C4 5933:C3 5928:C2 5923:C1 5574:S1 5569:R2 5564:R1 5559:Q1 5554:P4 5549:P3 5544:P2 5539:P1 5534:O6 5529:O4 5524:O3 5519:O1 5514:N4 5509:N3 5504:N2 5499:N1 5494:M1 5489:L2 5484:L1 5479:K2 5474:K1 5469:J3 5464:J2 5459:J1 5454:I3 5449:I2 5444:I1 5439:H1 5434:G1 5429:F2 5424:F1 5419:E3 5414:E1 5384:D4 5379:D3 5374:D2 5369:D1 5364:C2 5359:C1 5354:B2 5349:B1 5344:A3 5339:A2 5334:A1 5287:/ 5189:2B 5184:2A 5061:11 5034:: 5015:: 4991:20 4986:17 4981:16 4976:10 4804:1B 4799:1A 4579:EN 4418:D9 4413:D8 4408:D4 4403:D3 4398:D1 4373:C9 4368:C8 4363:C6 4358:C5 4353:C4 4343:B9 4338:B8 4333:B7 4328:B6 4323:B5 4318:B4 4313:B3 4308:B2 4303:B1 4283:A9 4278:A7 4273:A5 4268:A4 4263:A3 4258:A2 4253:A1 4051:1D 4046:1C 4041:1B 4036:1A 3798:74 3793:51 3788:44 3783:43 3778:41 3773:35 3768:34 3758:24 3753:22 3748:19 3743:10 3716:40 3711:33 3706:32 3701:21 3696:20 3691:17 3686:16 3681:11 3669:7B 3664:7A 3568:SP 3561:17 3556:15 3551:14 3546:13 3541:12 3536:11 3531:10 3386:S2 3381:S1 3259:3A 3254:2I 2812:II 2166:ID 2055:3A 2045:1A 1691:L3 1686:L2 1681:L1 1607:L1 1344:. 1334:. 1322:. 1318:. 1301:. 1287:. 1283:. 1266:. 1258:. 1246:. 1228:. 1218:. 1208:18 1206:. 1202:. 1174:. 1164:. 1156:. 1144:11 1142:. 1138:. 1115:. 1105:. 1097:. 1087:. 1077:90 1075:. 1071:. 1048:. 1038:. 1030:. 1018:11 1016:. 1012:. 989:. 979:. 971:. 961:69 959:. 955:. 932:. 924:. 912:39 910:. 906:. 883:. 873:. 861:. 857:. 845:^ 823:. 799:. 789:. 779:18 777:. 773:. 761:^ 747:. 739:. 731:. 721:52 719:. 715:. 701:^ 687:. 677:. 667:14 665:. 661:. 647:^ 633:. 625:. 615:. 582:. 572:. 564:. 554:. 542:. 538:. 515:. 505:. 491:. 487:. 469:^ 365:σ 328:σ 240:. 6769:/ 6760:C 6755:B 6750:A 6728:3 6723:2 6674:2 6617:/ 6563:2 6558:1 6417:4 6412:3 6407:2 6402:1 6383:4 6378:3 6373:1 6306:9 6301:8 6296:6 6291:5 6286:4 6281:3 6276:2 6271:1 6242:4 6237:3 6232:2 6227:1 6215:4 6210:3 6205:2 6200:1 6136:D 6131:C 6126:B 6121:A 6058:5 6053:3 6048:2 6043:1 5996:6 5991:5 5986:4 5981:3 5976:2 5971:1 5943:5 5837:4 5832:3 5827:2 5822:1 5787:8 5782:7 5777:6 5772:5 5767:4 5762:3 5757:2 5752:1 5735:6 5730:5 5725:4 5720:1 5698:2 5693:1 5676:4 5671:3 5666:1 5649:5 5644:4 5639:2 5614:4 5609:2 5604:1 5322:5 5317:4 5312:3 5307:2 5302:1 5268:3 5263:2 5258:1 5246:2 5241:1 5167:2 5162:1 5152:9 5147:8 5142:7 5137:6 5132:5 5127:4 5122:3 5117:2 5112:1 5083:2 5078:1 5056:7 5051:6 5041:2 5036:1 5027:C 5022:B 5017:A 4971:8 4966:6 4961:3 4956:1 4942:5 4937:4 4932:3 4927:2 4922:1 4910:2 4905:1 4893:3 4888:2 4883:1 4871:2 4866:1 4849:6 4844:5 4839:4 4834:3 4829:2 4824:1 4777:3 4772:2 4767:1 4626:2 4621:1 4589:2 4584:1 4572:2 4567:1 4553:6 4548:5 4543:4 4538:3 4533:2 4528:1 4516:2 4511:1 4218:4 4213:2 4208:1 4184:2 4179:1 4056:2 4024:4 4019:2 4014:1 3967:6 3738:9 3733:7 3728:3 3642:4 3637:3 3632:2 3627:1 3593:8 3588:7 3583:4 3578:2 3573:1 3526:9 3521:8 3516:7 3511:6 3506:5 3501:4 3496:3 3491:2 3486:1 3469:3 3464:2 3452:3 3447:2 3442:1 3430:3 3425:2 3420:1 3408:2 3403:1 3371:3 3366:2 3361:1 3339:4 3334:3 3329:2 3324:1 3292:6 3249:4 3244:2 3239:1 3229:2 3224:1 3212:2 3207:1 3173:2 3169:2 3150:3 3145:2 3140:1 3128:6 3123:5 3118:4 3113:3 3108:2 3103:1 3089:4 2964:γ 2959:β 2954:α 2925:β 2920:α 2878:4 2873:2 2861:γ 2856:β 2851:α 2834:γ 2829:α 2807:I 2805:( 2774:β 2769:α 2757:γ 2752:β 2747:α 2735:γ 2730:β 2725:α 2708:γ 2698:α 2686:β 2681:α 2659:β 2654:α 2630:) 2628:4 2579:ε 2574:δ 2569:γ 2564:β 2559:α 2529:6 2524:5 2519:4 2514:3 2509:2 2504:1 2480:) 2478:4 2471:7 2466:6 2454:9 2449:5 2444:3 2439:2 2434:1 2417:X 2412:C 2407:B 2402:A 2372:2 2367:1 2263:L 2258:2 2253:1 2241:7 2236:6 2231:5 2226:4 2221:3 2216:2 2211:1 2186:4 2181:3 2176:2 2171:1 2154:9 2149:3 2144:2 2119:2 2114:1 2097:3 2092:2 2087:1 2075:3 2070:2 2065:1 1926:2 1921:1 1882:2 1877:1 1865:3 1860:2 1855:1 1843:2 1838:1 1794:2 1789:1 1746:) 1742:( 1723:3 1718:2 1713:1 1676:2 1664:K 1659:G 1654:F 1649:B 1602:3 1597:1 1585:ζ 1580:ε 1575:δ 1570:γ 1565:β 1560:α 1538:2 1533:1 1474:7 1469:6 1464:5 1459:4 1454:3 1449:2 1444:1 1427:) 1423:( 1381:e 1374:t 1367:v 1352:. 1330:: 1309:. 1295:: 1289:2 1274:. 1254:: 1248:6 1236:. 1214:: 1182:. 1150:: 1123:. 1091:: 1083:: 1056:. 1024:: 997:. 967:: 940:. 918:: 891:. 869:: 839:. 807:. 785:: 755:. 727:: 695:. 673:: 641:. 611:: 590:. 558:: 550:: 544:6 523:. 499:: 493:5 353:σ 340:σ 313:σ 123:) 117:( 112:) 108:( 98:· 91:· 84:· 77:· 50:. 20:)

Index

Anti-sigma factor

verification
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adding citations to reliable sources
"Anti-sigma factors"
news
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JSTOR
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proteins
sigma factors
transcriptional
Escherichia coli
Salmonella
T4 bacteriophage
cytoplasmic
membrane-bound
flagellum
cell growth

RNA polymerase (RNAP)
Sigma factors
essential proteins
RNAP
gene regulation
cell differentiation
negative feedback

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