2617:β-Blockers still represent widely prescribed drugs as they cover a wide spectrum of CV indications. Obviously, it is not trivial which β-blocker to choose as they differ both with regard to their PD and PK profiles . It is well known when comparing the characteristics of atenolol, bisoprolol, metoprolol (each β-1 selective) and carvedilol (β-1 and β-2 nonselective). Among these β-blockers, atenolol is mainly eliminated by renal excretion; bisoprolol is in part excreted as parent compound via the renal route (50%); the other 50% are hepatically metabolized; whereas metoprolol and carvedilol are metabolized by CYP2D6. DDIs are mainly observed with those β-blockers that are metabolized via CYP enzymes. However, it should be emphasized that, in general, β-blockers are well-tolerated safe drugs with a large therapeutic index .
2576:
pharmacokinetics of atenolol. In fact it has been shown that plasma concentrations of nonmetabolized atenolol was not significantly different between "extensive" and "poor debrisoquine metabolizers" – in contrast to the plasma concentrations of metoprolol that were significantly increased in "poor metabolizers" (Dayer et al. 1985, Lewis et al. 1985). Furthermore, in healthy volunteers cimetidine (CAS 70059- 30-2) did not affect plasma concentrations of atenolol but significantly increased plasma concentrations of metoprolol or propranolol (Kirch et al. 1981).
622:
599:
2692:
vesicles and blocking of norepinephrine reuptake.116,117 In addition, amphetamines are potent blockers of dopamine uptake and strong central nervous system stimulants. Dopaminergic
Effects of Amphetamines: In addition to the β-agonist effects of amphetamines, the dopamine receptors D1 and D2 contribute to the cardiovascular effects of methamphetamine by producing a pressor response accounting for the increase in blood pressure. The D1 receptor also is involved in mediating the positive tachycardic effects of methamphetamine.117
40:
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31:
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attacks as other classes of medicines such as diuretics, calcium-channel blockers, and renin-angiotensin system inhibitors. Most of these findings come from one type of beta-blocker called atenolol. However, beta-blockers are a diverse group of medicines with different properties, and we need more well-conducted research in this area." (p. 2-3)
2102:
Further research should be of high quality and should explore whether there are differences between different subtypes of beta-blockers or whether beta-blockers have differential effects on younger and older people Beta-blockers were not as good at preventing the number of deaths, strokes, and heart
2929:
Postural hypotension is also a risk when antipsychotics are taken with β-blockers (probably because of pharmacokinetic interaction) or with diuretics (because of Na+ or volume depletion). The same hypotensive effects might be anticipated when tricyclic antidepressants or MAOIs are co-prescribed with
2890:
Interestingly, in one study, orthostatic hypotension was eliminated in a group of 61 patients treated for migraine headaches with phenelzine, when a beta-blocker, atenolol, was added (15). The authors have reported that hypertensive reactions were also less frequent when the two drugs were combined.
1077:
will terminate bronchospasms. Blood or plasma atenolol concentrations may be measured to confirm a diagnosis of poisoning in hospitalized patients or to assist in a medicolegal death investigation. Plasma levels are usually less than 3 mg/L during therapeutic administration, but can range from
1523:
that indicates that a drug is not as effective as others in treating some conditions. In 2012, 33.8 million prescriptions were written to
American patients for this drug. In 2014, it was in the top (most common) 1% of drugs prescribed to Medicare patients. Although the number of prescriptions has
2664:
Vetter VL, Elia J, Erickson C, Berger S, Blum N, Uzark K, et al. (May 2008). "Cardiovascular monitoring of children and adolescents with heart disease receiving medications for attention deficit/hyperactivity disorder : a scientific statement from the
American Heart Association Council on
2691:
Amphetamines (Adderall, Dexedrine): Electrophysiological
Effects of Amphetamines: Amphetamines have been associated with tachyarrhythmias and sudden death.113–115 Many of the electrophysiological effects of amphetamines may be initiated by the release of norepinephrine stores from presynaptic
2575:
Atenolol is only minimally, if at all, metabolized and renally excreted in mostly unchanged form; thus an interaction with drugs that interfere with the hepatic metabolism is not to be expected. It is also very unlikely that the genetic polymorphisms of the CYP-family might affect the
997:
Hypertension treated with a β-blocker such as atenolol, alone or in conjunction with a thiazide diuretic, is associated with a higher incidence of new onset type 2 diabetes mellitus compared to those treated with an ACE inhibitor or angiotensin receptor blocker.
1524:
been declining steadily since limited evidence articles contesting its efficacy was published, it has been estimated that it would take 20 years for doctors to stop prescribing it for hypertension. Despite its diminished efficacy when compared to newer
2780:
Hassan NA, Gunaid AA, El-Khally FM, Al-Noami MY, Murray-Lyon IM (April 2005). "Khat chewing and arterial blood pressure. A randomized controlled clinical trial of alpha-1 and selective beta-1 adrenoceptor blockade".
1536:
are a diverse group of medicines with different properties that still requires further research. As consequence, reasons for the popularity of beta blockers cannot be fully attributed to a slow healthcare system –
2891:
We need further experience with this combination to determine whether addition of a beta-blocker is a safe and an effective strategy for alleviation of postural hypotension in depressed patients receiving an MAOI.
1203:
reactions with phenelzine. However, more research is still needed to assess whether addition of a beta blocker like atenolol to MAOI therapy is safe and effective for improving orthostatic hypotension with MAOIs.
2211:
Lindholm LH, Ibsen H, Borch-Johnsen K, Olsen MH, Wachtell K, Dahlöf B, et al. (September 2002). "Risk of new-onset diabetes in the
Losartan Intervention For Endpoint reduction in hypertension study".
2745:
Mores N, Campia U, Navarra P, Cardillo C, Preziosi P (June 1999). "No cardiovascular effects of single-dose pseudoephedrine in patients with essential hypertension treated with beta-blockers".
2629:
Richards JR, Albertson TE, Derlet RW, Lange RA, Olson KR, Horowitz BZ (May 2015). "Treatment of toxicity from amphetamines, related derivatives, and analogues: a systematic clinical review".
924:
The role for β-blockers in general in hypertension was downgraded in June 2006 in the United
Kingdom, and later in the United States, as they are less appropriate than other agents such as
2930:
peripheral antihypertensive agonists. One possible exception concerns phenelzine, whose hypotensive action was reversed on co-therapy with atenolol (Merikangas & Merikangas, 1995).
235:
1467:
hours. The half-life of atenolol does not change with continuous administration. With intravenous administration, atenolol levels rapidly decline (5- to 10-fold) during the first 7
3139:
2835:
O'Connell MB, Gross CR (1991). "The effect of multiple doses of phenylpropanolamine on the blood pressure of patients whose hypertension was controlled with beta blockers".
2466:
DeLima LG, Kharasch ED, Butler S (July 1995). "Successful pharmacologic treatment of massive atenolol overdose: sequential hemodynamics and plasma atenolol concentrations".
1652:
3534:
2431:
Messerli FH, Grossman E, Goldbourt U (June 1998). "Are beta-blockers efficacious as first-line therapy for hypertension in the elderly? A systematic review".
2120:
190:
2808:
O'Connell MB, Gross CR (1990). "The effect of single-dose phenylpropanolamine on blood pressure in patients with hypertension controlled by beta blockers".
2298:
Lindholm LH, Carlberg B, Samuelsson O (October 2005). "Should β blockers remain first choice in the treatment of primary hypertension? A meta-analysis".
3611:
4476:
4456:
1303:
orthostatic tachycardia. The beta-blocking effects of atenolol, as measured by reduction of exercise-related tachycardia, are apparent within 1
62:
5964:
3527:
717:
2116:
6324:
3129:
5842:
1395:
profile of atenolol results in it having relatively consistent plasma drug levels with about 4-fold variation between individuals.
691:
6299:
6149:
3520:
3228:
925:
2255:
Elliott WJ, Meyer PM (January 2007). "Incident diabetes in clinical trials of antihypertensive drugs: a network meta-analysis".
1644:
1519:
Atenolol has been given as an example of how slow healthcare providers are to change their prescribing practices in the face of
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5815:
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5806:
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1941:
870:
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2005:
1697:
1471:
hours and thereafter decline at a rate similar to that with oral administration. The elimination of atenolol is slowed in
5833:
1242:
1049:
and bronchospastic reactions. Treatment is largely symptomatic. Hospitalization and intensive monitoring is indicated.
6019:
6004:
2665:
Cardiovascular
Disease in the Young Congenital Cardiac Defects Committee and the Council on Cardiovascular Nursing".
1889:
1832:
737:
762:
113:
3495:
1772:"β-Blockers in hypertension, diabetes, heart failure and acute myocardial infarction: a review of the literature"
372:
220:
94:
1125:. Most of these interactions involve either additive cardiovascular effects or reduction of atenolol's effects.
745:
InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
6119:
5851:
2865:
Gadde KM, Krishnan KR (1998). "Management of Side
Effects of Monoamine Oxidase Inhibitors". In Balon R (ed.).
2521:
1150:. As a result, it has little or no potential for cytochrome P450-related drug interactions, for instance with
6192:
4842:
2947:"Combination monoamine oxidase inhibitor and beta-blocker treatment of migraine, with anxiety and depression"
1356:
937:
447:
6251:
5797:
2706:"Pharmacological mechanisms in the cardiovascular effects of methamphetamine in conscious squirrel monkeys"
910:
617:
498:
1009:
may be associated with better cardiovascular and cerebrovascular outcomes than β-blockers in the elderly.
4676:
4226:
3966:
3554:
3442:
3221:
1559:"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)"
1250:
1188:
906:
578:
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1442:
1388:
1254:
1234:
1170:
1129:
851:
1363:
is rapid and consistent but is incomplete. About 50% of an oral dose of atenolol is absorbed from the
1331:
mg. With intravenous administration, maximal reduction in exercise-related tachycardia occurs within 5
877:. In 2022, it was the 63rd most commonly prescribed medication in the United States, with more than 10
337:
5879:
1905:
1558:
1090:
808:
567:
1253:. However, the preferential action of atenolol is not absolute, and at high doses it can also block
6314:
4149:
3250:
1483:
1284:
594:
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1226:
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1407:
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1114:
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929:
914:
150:
52:
1770:
DiNicolantonio JJ, Fares H, Niazi AK, Chatterjee S, D'Ascenzo F, Cerrato E, et al. (2015).
6304:
6223:
6139:
6134:
6029:
4562:
4254:
4244:
3815:
3572:
3214:
2343:"Re-examining the efficacy of beta-blockers for the treatment of hypertension: a meta-analysis"
1411:
1399:
281:
2993:
Cojocariu SA, Maștaleru A, Sascău RA, Stătescu C, Mitu F, Leon-Constantin MM (February 2021).
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1879:
1541:
factor, such as treatment cost and duration, also affect adherence and popularity of therapy.
6094:
5959:
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4180:
2866:
1525:
1503:
1460:
804:
702:
547:
438:
306:
161:
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1005:
and mortality in patients over 60 years old compared to other antihypertensive medications.
6241:
5872:
5420:
980:
507:
402:
324:
173:
3095:
487:
8:
6294:
5099:
4965:
4441:
4347:
3744:
3650:
3543:
2591:
Scheen AJ (September 2011). "Cytochrome P450-mediated cardiovascular drug interactions".
1376:
1360:
1324:
1230:
1222:
1185:
1038:
953:
835:
800:
780:
393:
316:
183:
157:
621:
598:
3546:
3187:
3162:
3021:
2994:
2392:"Atenolol vs nonatenolol β-blockers for the treatment of hypertension: a meta-analysis"
2367:
2342:
2323:
2280:
2237:
2088:
2063:
1796:
1771:
1747:
1720:
1538:
1344:
1300:
1265:
1050:
918:
874:
124:
2678:
2549:
Brodde OE, Kroemer HK (2003). "Drug-drug interactions of beta-adrenoceptor blockers".
2311:
2268:
5979:
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5425:
4303:
4053:
3918:
3192:
3026:
2968:
2963:
2946:
2920:
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2844:
2817:
2790:
2762:
2727:
2722:
2705:
2682:
2646:
2642:
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2566:
2483:
2479:
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2315:
2272:
2229:
2225:
2163:
2093:
1997:
1885:
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1801:
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1456:
with oral administration and more than 85% in urine with intravenous administration.
1122:
956:
831:
819:
86:
2327:
2284:
2241:
1848:
1001:β-blockers, of which atenolol is mainly studied, provides weaker protection against
5500:
5064:
4907:
4706:
4284:
4046:
4036:
3597:
3182:
3174:
3016:
3006:
2958:
2912:
2754:
2717:
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2638:
2600:
2558:
2475:
2440:
2403:
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2354:
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2221:
2155:
2083:
2079:
2075:
1913:
1791:
1783:
1742:
1732:
1472:
1415:
1347:
of atenolol is dose-related and is correlated with circulating levels of atenolol.
1316:
1151:
1086:
960:
902:
634:
263:
203:
1933:
6278:
6109:
5949:
4298:
3606:
3512:
3044:
2604:
2159:
1392:
1312:
1246:
1166:
1144:
890:
869:
Atenolol was patented in 1969 and approved for medical use in 1975. It is on the
707:
427:
301:
291:
271:
176:
2027:
1963:
1787:
1689:
72:
5919:
5410:
5079:
5044:
4765:
4521:
4431:
4184:
4049:
3769:
3724:
3489:
2505:(8th ed.). Foster City, Calif.: Biomedical Publications. pp. 116–117.
2408:
2391:
1989:
1721:"Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease"
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1162:
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788:
6288:
5974:
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5909:
5560:
5400:
5084:
5028:
4985:
4646:
4570:
4436:
4375:
4264:
4153:
4065:
3819:
3739:
3734:
3678:
3665:
3161:
Choi HY, Oh IJ, Lee JA, Lim J, Kim YS, Jeon TH, et al. (November 2018).
3011:
2924:
2444:
1910:
World Health
Organization model list of essential medicines: 22nd list (2021)
1403:
1292:
1042:
972:
847:
823:
610:
248:
6218:
6164:
6154:
6084:
5994:
5944:
5939:
5585:
5570:
5515:
5010:
4832:
4777:
4769:
4741:
4701:
4620:
4586:
4401:
4196:
4188:
4169:
4157:
4041:
3910:
3886:
3846:
3308:
3241:
3237:
3196:
3134:
3030:
2794:
2766:
2686:
2650:
2612:
2570:
2562:
2417:
2376:
2319:
2276:
2233:
2167:
2097:
2001:
1805:
1756:
1533:
1529:
1402:
of atenolol is 6 to 16%. Atenolol is classified as a beta blocker with low
1218:
1200:
1174:
1118:
1102:
1070:
1046:
992:
894:
839:
776:
198:
2972:
2848:
2821:
2758:
2731:
2487:
2452:
1737:
787:. Although used to treat high blood pressure, it does not seem to improve
6159:
6114:
6104:
6099:
6079:
6074:
6059:
6054:
6039:
6009:
5969:
5924:
5914:
5895:
5710:
5685:
5680:
5675:
5565:
5540:
5525:
5510:
5475:
5460:
5440:
5435:
5405:
5385:
5360:
5345:
5290:
5235:
5164:
5159:
5154:
5114:
5109:
5015:
5000:
4970:
4960:
4945:
4916:
4887:
4731:
4721:
4696:
4686:
4651:
4594:
4557:
4486:
4481:
4461:
4426:
4362:
4337:
4327:
4308:
4269:
4139:
4016:
4011:
3971:
3946:
3936:
3926:
3896:
3891:
3866:
3841:
3835:
3800:
3759:
3754:
3719:
3704:
3699:
3645:
3635:
3616:
3577:
3313:
3178:
1532:
are still a relevant clinical choice for treating some conditions, since
1430:
1288:
1178:
1034:
1030:
815:
80:
22:
3069:
2916:
2358:
1918:
1410:
and entering the brain. This in turn may result in fewer effects in the
1383:
hours following an oral dose, whereas peak concentrations occur within 5
467:
39:
6144:
6129:
6089:
6069:
6049:
6034:
5989:
5984:
5954:
5775:
5765:
5755:
5740:
5735:
5720:
5700:
5695:
5670:
5665:
5650:
5630:
5625:
5620:
5590:
5580:
5575:
5545:
5535:
5495:
5485:
5465:
5415:
5395:
5375:
5370:
5350:
5335:
5330:
5320:
5300:
5295:
5285:
5280:
5275:
5255:
5240:
5230:
5210:
5189:
5174:
5149:
5144:
5139:
5124:
5119:
5104:
5089:
5074:
5069:
5059:
5049:
5005:
4990:
4980:
4955:
4950:
4931:
4921:
4902:
4897:
4877:
4872:
4862:
4857:
4847:
4837:
4827:
4817:
4812:
4756:
4746:
4736:
4726:
4666:
4656:
4636:
4631:
4616:
4590:
4582:
4578:
4552:
4547:
4496:
4491:
4471:
4466:
4421:
4411:
4406:
4396:
4357:
4342:
4332:
4293:
4279:
4175:
4165:
4126:
4121:
4111:
4106:
4096:
4081:
4057:
4031:
4021:
4006:
4001:
3991:
3986:
3956:
3941:
3914:
3876:
3862:
3858:
3854:
3831:
3827:
3790:
3749:
3729:
3709:
3694:
3660:
3640:
3592:
3587:
3459:
3454:
3432:
3395:
3375:
3370:
3365:
3350:
3323:
3299:
3294:
3284:
3279:
3269:
3264:
3259:
2146:
Cruickshank JM (August 2007). "Are we misunderstanding beta-blockers".
2062:
Wiysonge CS, Bradley HA, Volmink J, Mayosi BM, Opie LH (January 2017).
1506:
of atenolol is 0.16 and its predicted log P ranges from −0.03 to 0.57.
1480:
1434:
1422:
1272:
1192:
1136:
1106:
1074:
1062:
863:
796:
667:
478:
168:
3206:
2903:
O'Brien P, Oyebode F (2003). "Psychotropic medication and the heart".
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6014:
5999:
5770:
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5725:
5715:
5690:
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5610:
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5550:
5520:
5490:
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5430:
5390:
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5355:
5340:
5315:
5310:
5305:
5270:
5265:
5245:
5215:
5179:
5134:
5129:
5094:
5054:
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4975:
4936:
4882:
4867:
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4822:
4783:
4751:
4716:
4711:
4681:
4626:
4608:
4604:
4574:
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4506:
4446:
4416:
4391:
4352:
4318:
4274:
4212:
4143:
4135:
4116:
4101:
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4086:
4071:
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4026:
3996:
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3976:
3961:
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3901:
3881:
3870:
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3810:
3805:
3795:
3785:
3714:
3655:
3626:
3582:
3464:
3410:
3405:
3400:
3390:
3360:
3274:
1449:
1368:
1364:
1110:
1094:
843:
827:
792:
413:
347:
66:
30:
6182:
6064:
6044:
5655:
5645:
5595:
5470:
5455:
5450:
5225:
5220:
5194:
5169:
5036:
4926:
4892:
4773:
4671:
4661:
4641:
4612:
4598:
4542:
4516:
4501:
4383:
4313:
4202:
4192:
4076:
3922:
3906:
3850:
3686:
3621:
3380:
3304:
1269:
1058:
1054:
1018:
1006:
933:
527:
458:
108:
1769:
791:
in those with the condition. Other uses include the prevention of
690:
5750:
5730:
5705:
5600:
5325:
5250:
5184:
4691:
4511:
4259:
4207:
4161:
3764:
3385:
3328:
3318:
3289:
1438:
1296:
2992:
959:. It is also available in the form of oral tablets containing a
6202:
5020:
4367:
4249:
3670:
2210:
1446:
1147:
1132:
1002:
898:
784:
558:
5864:
2868:
Practical
Management of the Side Effects of Psychotropic Drugs
2871:. Medical Psychiatry Series. CRC Press. pp. 67–83 (71).
2779:
2704:
Schindler CW, Zheng JW, Tella SR, Goldberg SR (August 1992).
1827:(76 ed.). Pharmaceutical Press. 2018. pp. 151–153.
1453:
1426:
1372:
1140:
859:
681:
538:
352:
3163:"Factors Affecting Adherence to Antihypertensive Medication"
2628:
2061:
1964:"Atenolol Drug Usage Statistics, United States, 2013 - 2022"
583:
4451:
2995:"Neuropsychiatric Consequences of Lipophilic Beta-Blockers"
2940:
2938:
2703:
2622:
1981:
1184:
Atenolol has been found to be safe in combination with the
518:
2744:
2297:
1065:
can be given against hypotension and the inhalation of a β
2430:
1904:
1566:
1475:, with the elimination rate being closely related to the
2935:
2773:
2663:
807:(injection into a vein). It can also be used with other
2697:
1264:
Beta-blocking effects of atenolol include reduction in
871:
World Health Organization's List of Essential Medicines
2738:
2657:
889:
Atenolol is used for a number of conditions including
6262:
2121:
National Institute for Health and Clinical Excellence
1479:
and with significant accumulation occurring when the
2944:
2544:
2542:
2465:
2117:"NICE and BHS launch updated hypertension guideline"
1161:
Beta blockers like atenolol can reduce or block the
948:
Atenolol is available in the form of 25, 50, and 100
3070:"Atenolol: Uses, Interactions, Mechanism of Action"
1551:
446:
3542:
2902:
2834:
2807:
1429:. This is in contrast to other beta blockers like
2896:
2828:
2801:
2539:
2516:
2514:
2512:
2032:The American Society of Health-System Pharmacists
1987:
1718:
1315:effects of atenolol, including beta-blocking and
1021:are due to excessive pharmacodynamic actions on β
6286:
1639:
1637:
1635:
1633:
1631:
1629:
1627:
1625:
1623:
1621:
1619:
1617:
1615:
1613:
1611:
1609:
1607:
1605:
1603:
983:as well, but this formulation was discontinued.
426:
2988:
2986:
2984:
2982:
2503:Disposition of Toxic Drugs and Chemicals in Man
2139:
2057:
2055:
2053:
1996:. Treasure Island (FL): StatPearls Publishing.
1877:
1601:
1599:
1597:
1595:
1593:
1591:
1589:
1587:
1585:
1583:
401:
2945:Merikangas KR, Merikangas JR (November 1995).
2509:
5880:
3528:
3222:
2864:
2586:
2584:
2548:
2527:. Food and Drug Administration. December 2023
2340:
1514:
1441:. Instead of hepatic metabolism, atenolol is
307:
5965:Budesonide/glycopyrronium bromide/formoterol
3160:
3130:"When Evidence Says No, But Doctors Say Yes"
2979:
2860:
2858:
2424:
2254:
2181:
2179:
2177:
2050:
1580:
975:. Atenolol was previously available in a 0.5
112:
2145:
2068:The Cochrane Database of Systematic Reviews
1406:and hence lower potential for crossing the
255:In general: ℞ (Prescription only)
5887:
5873:
3535:
3521:
3229:
3215:
3088:
2581:
2389:
1684:
1682:
1680:
1678:
1676:
1674:
1672:
1670:
620:
597:
486:
3186:
3020:
3010:
2962:
2855:
2721:
2522:"TENORMIN® (atenolol) Tablets Drug Label"
2407:
2366:
2174:
2087:
1917:
1795:
1746:
1736:
846:and alternative drugs are preferred when
506:
3062:
1825:British national formulary : BNF 76
1311:hours following a single oral dose. The
3236:
3127:
3037:
2108:
1819:
1817:
1815:
1667:
1295:(a non-selective β-adrenergic receptor
593:
466:
85:
6287:
2590:
2500:
1898:
1884:. John Wiley & Sons. p. 461.
1871:
1690:"Atenolol Monograph for Professionals"
1645:"DailyMed - TENORMIN- atenolol tablet"
1509:
1287:at rest and with exercise, inhibition
611:
5868:
3516:
3210:
3123:
3121:
3119:
3117:
2114:
1988:Rehman B, Sanchez DP, Shah S (2021).
1912:. Geneva: World Health Organization.
1859:from the original on 23 December 2018
1725:International Journal of Hypertension
838:. Other serious side effects include
566:
546:
242:
103:
71:
6247:
2020:
2008:from the original on 10 October 2022
1812:
1655:from the original on 27 January 2022
1078:3–30 mg/L in overdose victims.
202:
2148:International Journal of Cardiology
1944:from the original on 30 August 2024
1350:
1212:
779:medication primarily used to treat
526:
417:
356:
13:
3114:
2396:The Canadian Journal of Cardiology
2341:Khan N, McAlister FA (June 2006).
2038:from the original on 18 April 2019
1849:"Atenolol use while Breastfeeding"
1700:from the original on 18 April 2019
1307:hour and are maximal within 2 to 4
1243:intrinsic sympathomimetic activity
943:
14:
6336:
6325:N-isopropyl-phenoxypropanolamines
6020:Glycopyrronium bromide/formoterol
3167:Korean Journal of Family Medicine
2905:Advances in Psychiatric Treatment
2679:10.1161/CIRCULATIONAHA.107.189473
1335:minutes and following a single 10
1115:prostaglandin synthase inhibitors
229:
135:
6272:
6246:
6237:
6236:
2643:10.1016/j.drugalcdep.2015.01.040
2480:10.1097/00000542-199507000-00025
2226:10.1097/00004872-200209000-00035
2064:"Beta-blockers for hypertension"
1719:Tomiyama H, Yamashina A (2014).
1421:Atenolol undergoes little to no
1339:mg dose has dissipated within 12
842:. Use is not recommended during
651:
645:
38:
29:
5894:
5843:Monoamine metabolism modulators
3154:
3142:from the original on 9 May 2018
2494:
2459:
2390:Kuyper LM, Khan NA (May 2014).
2383:
2334:
2291:
2248:
2204:
2187:"Drugs@FDA: FDA-Approved Drugs"
1956:
1926:
1878:Fischer J, Ganellin CR (2006).
1207:
1081:
986:
940:, particularly in the elderly.
884:
750:Key:METKIMKYRPQLGS-UHFFFAOYSA-N
6300:Drugs developed by AstraZeneca
6120:Sodium zirconium cyclosilicate
2593:Expert Opin Drug Metab Toxicol
2080:10.1002/14651858.CD002003.pub5
1841:
1763:
1712:
1452:. Atenolol is excreted 50% in
1053:is useful to absorb the drug.
725:O=C(N)Cc1ccc(cc1)OCC(O)CNC(C)C
657:
639:
1:
6193:Cambridge Antibody Technology
5825:Monoamine reuptake inhibitors
5798:Receptor/signaling modulators
2312:10.1016/S0140-6736(05)67573-3
2269:10.1016/s0140-6736(07)60108-1
1881:Analogue-based Drug Discovery
1544:
1319:effects, last for at least 24
1251:membrane-stabilizing activity
1091:catecholamine-depleting drugs
1057:will counteract bradycardia,
938:angiotensin receptor blockers
312:Tooltip Intravenous injection
6310:Peripherally selective drugs
2964:10.1016/0006-3223(95)00077-1
2723:10.1016/0091-3057(92)90031-a
2605:10.1517/17425255.2011.586337
2160:10.1016/j.ijcard.2007.01.069
1497:
911:supraventricular tachycardia
7:
6320:Products introduced in 1976
4908:Deoxyepinephrine (epinine,
4285:Deoxyepinephrine (epinine,
4132:Tetracyclic antidepressants
3598:Deoxyepinephrine (epinine,
1788:10.1136/openhrt-2014-000230
1463:of atenolol is about 6 to 7
1414:as well as a lower risk of
1189:monoamine oxidase inhibitor
1012:
907:acute myocardial infarction
785:heart-associated chest pain
10:
6341:
5834:Monoamine releasing agents
3128:Epstein D (22 July 2017).
2409:10.1016/j.cjca.2014.01.006
1922:. WHO/MHP/HPS/EML/2021.02.
1515:Changing medical practices
1477:glomerular filtration rate
1389:intravenous administration
1029:-receptors. These include
990:
809:blood pressure medications
629:Chemical and physical data
6232:
6211:
6173:
5902:
5788:
5203:
4805:
4796:
4530:
4237:
4225:
4150:Tricyclic antidepressants
3778:
3565:
3553:
3473:
3441:
3419:
3337:
3249:
1906:World Health Organization
1061:helps with hypoglycemia,
1033:(slow heartbeat), severe
795:and treatment of certain
758:
733:
713:
701:
679:
666:
633:
628:
609:
577:
557:
537:
517:
497:
477:
457:
437:
412:
392:
368:
363:
346:
336:
323:
300:
290:
280:
270:
262:
219:
214:
189:
167:
149:
123:
93:
79:
61:
51:
46:
37:
28:
3012:10.3390/medicina57020155
2445:10.1001/jama.279.23.1903
2115:Ladva S (28 June 2006).
1379:of atenolol occur 2 to 4
1285:diastolic blood pressure
1099:calcium channel blockers
930:calcium channel blockers
6188:Alexion Pharmaceuticals
4563:Atypical antipsychotics
3816:Atypical antipsychotics
2710:Pharmacol Biochem Behav
2214:Journal of Hypertension
1229:. It is specifically a
1197:orthostatic hypotension
915:ventricular tachycardia
881:million prescriptions.
873:. It is available as a
850:. It works by blocking
384:)-2-{4-phenyl}acetamide
16:Beta blocker medication
6140:Trastuzumab deruxtecan
6135:Tixagevimab/cilgavimab
6030:Isosorbide mononitrate
4762:Typical antipsychotics
4245:(R)-3-Nitrobiphenyline
4181:Typical antipsychotics
2563:10.1055/s-0031-1299835
1526:antihypertensive drugs
1412:central nervous system
1400:plasma protein binding
1377:Maximal concentrations
1227:β-adrenergic receptors
1195:and actually improved
1089:with atenolol include
917:, and the symptoms of
862:, thus decreasing the
6095:Salbutamol/budesonide
5960:Budesonide/formoterol
5852:Monoamine neurotoxins
2759:10.1007/s002280050624
2551:Arzneimittelforschung
1934:"The Top 300 of 2022"
1528:, atenolol and other
1461:elimination half-life
1259:-adrenergic receptors
856:-adrenergic receptors
805:intravenous injection
797:irregular heart beats
5421:Dichloroisoprenaline
3179:10.4082/kjfm.17.0041
2747:Eur J Clin Pharmacol
1437:, but is similar to
1299:), and reduction of
1239:-adrenergic receptor
1123:digitalis glycosides
5100:Phenylpropanolamine
4966:Ethylnorepinephrine
4442:Phenylpropanolamine
4348:Ethylnorepinephrine
3745:Phenylpropanolamine
3651:Ethylnorepinephrine
3544:Adrenergic receptor
2917:10.1192/apt.9.6.414
2631:Drug Alcohol Depend
2402:(5 Suppl): S47-53.
2359:10.1503/cmaj.060110
2306:(9496): 1545–1553.
1738:10.1155/2014/919256
1510:Society and culture
1408:blood–brain barrier
1361:oral administration
1128:Atenolol is mainly
979:mg/mL solution for
836:shortness of breath
781:high blood pressure
238:(Prescription only)
25:
6176:acquired companies
3500:Never to phase III
2191:accessdata.fda.gov
1539:patient compliance
1345:duration of action
1327:doses of 50 or 100
1233:antagonist of the
1158:of these enzymes.
1051:Activated charcoal
967:mg atenolol and 50
919:alcohol withdrawal
875:generic medication
338:Duration of action
21:
6260:
6259:
5980:Disufenton sodium
5862:
5861:
5855:
5846:
5837:
5828:
5819:
5810:
5801:
5784:
5783:
5531:Iodocyanopindolol
5506:Hydroxytertatolol
5426:Dihydroalprenolol
5039:
5031:
5023:
4940:
4792:
4791:
4386:
4378:
4370:
4322:
4304:Dihydroergotamine
4221:
4220:
4054:hydroxynefazodone
3919:dihydroergotamine
3689:
3681:
3673:
3630:
3510:
3509:
2999:Medicina (Kaunas)
2878:978-0-8247-4630-8
2673:(18): 2407–2423.
2501:Baselt R (2008).
1502:The experimental
1359:of atenolol with
1069:-mimetic such as
803:(by mouth) or by
770:
769:
692:Interactive image
579:CompTox Dashboard
246:
233:
139:
106:
6332:
6277:
6276:
6275:
6268:
6250:
6249:
6240:
6239:
6224:Louis Schweitzer
6174:Predecessors and
5889:
5882:
5875:
5866:
5865:
5849:
5840:
5831:
5822:
5813:
5804:
5792:
5501:Hydroxycarteolol
5065:Methoxyphenamine
5037:
5029:
5024:-DOPA (levodopa)
5021:
4938:
4912:-methyldopamine)
4803:
4802:
4707:Phenoxybenzamine
4384:
4376:
4371:-DOPA (levodopa)
4368:
4320:
4289:-methyldopamine)
4235:
4234:
4047:Phenylpiperazine
4037:Phenoxybenzamine
3687:
3679:
3674:-DOPA (levodopa)
3671:
3628:
3612:Dexisometheptene
3602:-methyldopamine)
3563:
3562:
3537:
3530:
3523:
3514:
3513:
3231:
3224:
3217:
3208:
3207:
3201:
3200:
3190:
3158:
3152:
3151:
3149:
3147:
3125:
3112:
3111:
3109:
3107:
3092:
3086:
3085:
3083:
3081:
3076:. 13 August 2004
3066:
3060:
3059:
3057:
3055:
3041:
3035:
3034:
3024:
3014:
2990:
2977:
2976:
2966:
2942:
2933:
2932:
2900:
2894:
2893:
2887:
2885:
2862:
2853:
2852:
2832:
2826:
2825:
2805:
2799:
2798:
2777:
2771:
2770:
2742:
2736:
2735:
2725:
2701:
2695:
2694:
2661:
2655:
2654:
2626:
2620:
2619:
2599:(9): 1065–1082.
2588:
2579:
2578:
2546:
2537:
2536:
2534:
2532:
2526:
2518:
2507:
2506:
2498:
2492:
2491:
2463:
2457:
2456:
2428:
2422:
2421:
2411:
2387:
2381:
2380:
2370:
2338:
2332:
2331:
2295:
2289:
2288:
2252:
2246:
2245:
2208:
2202:
2201:
2199:
2197:
2183:
2172:
2171:
2143:
2137:
2136:
2134:
2132:
2123:. Archived from
2112:
2106:
2105:
2091:
2059:
2048:
2047:
2045:
2043:
2024:
2018:
2017:
2015:
2013:
1985:
1979:
1978:
1976:
1974:
1960:
1954:
1953:
1951:
1949:
1930:
1924:
1923:
1921:
1902:
1896:
1895:
1875:
1869:
1868:
1866:
1864:
1845:
1839:
1838:
1821:
1810:
1809:
1799:
1767:
1761:
1760:
1750:
1740:
1716:
1710:
1709:
1707:
1705:
1686:
1665:
1664:
1662:
1660:
1651:. 30 June 2021.
1641:
1578:
1577:
1575:
1573:
1563:nctr-crs.fda.gov
1555:
1521:medical evidence
1493:
1489:
1486:rate is under 35
1473:renal impairment
1470:
1466:
1416:neuropsychiatric
1386:
1382:
1367:, with the rest
1351:Pharmacokinetics
1342:
1338:
1334:
1330:
1323:hours following
1322:
1317:antihypertensive
1310:
1306:
1213:Pharmacodynamics
1167:sympathomimetics
978:
970:
966:
951:
903:long QT syndrome
880:
766:
765:
694:
674:
659:
653:
647:
641:
624:
613:
602:
601:
587:
585:
570:
550:
530:
510:
490:
470:
450:
430:
420:
419:
405:
358:
328:
313:
309:
251:
244:
241:
231:
228:
206:
137:
134:
116:
105:
102:
89:
75:
57:Tenormin, others
42:
33:
26:
24:
20:
6340:
6339:
6335:
6334:
6333:
6331:
6330:
6329:
6315:1976 in science
6285:
6284:
6283:
6273:
6271:
6263:
6261:
6256:
6228:
6207:
6175:
6169:
6110:Sebelipase alfa
5950:Brompheniramine
5898:
5893:
5863:
5858:
5780:
5199:
4788:
4526:
4299:Dexmedetomidine
4230:
4217:
4050:antidepressants
3774:
3607:Desglymidodrine
3558:
3549:
3541:
3511:
3506:
3505:
3490:Clinical trials
3469:
3448:- + β-selective
3446:
3437:
3424:
3415:
3342:
3333:
3253:, non-selective
3245:
3235:
3205:
3204:
3159:
3155:
3145:
3143:
3126:
3115:
3105:
3103:
3094:
3093:
3089:
3079:
3077:
3074:DrugBank Online
3068:
3067:
3063:
3053:
3051:
3043:
3042:
3038:
2991:
2980:
2951:Biol Psychiatry
2943:
2936:
2901:
2897:
2883:
2881:
2879:
2863:
2856:
2837:Pharmacotherapy
2833:
2829:
2810:Pharmacotherapy
2806:
2802:
2778:
2774:
2743:
2739:
2702:
2698:
2662:
2658:
2627:
2623:
2589:
2582:
2557:(12): 814–822.
2547:
2540:
2530:
2528:
2524:
2520:
2519:
2510:
2499:
2495:
2464:
2460:
2429:
2425:
2388:
2384:
2353:(12): 1737–42.
2339:
2335:
2296:
2292:
2263:(9557): 201–7.
2253:
2249:
2209:
2205:
2195:
2193:
2185:
2184:
2175:
2144:
2140:
2130:
2128:
2113:
2109:
2074:(1): CD002003.
2060:
2051:
2041:
2039:
2026:
2025:
2021:
2011:
2009:
1986:
1982:
1972:
1970:
1962:
1961:
1957:
1947:
1945:
1932:
1931:
1927:
1903:
1899:
1892:
1876:
1872:
1862:
1860:
1847:
1846:
1842:
1835:
1823:
1822:
1813:
1768:
1764:
1717:
1713:
1703:
1701:
1688:
1687:
1668:
1658:
1656:
1643:
1642:
1581:
1571:
1569:
1557:
1556:
1552:
1547:
1517:
1512:
1500:
1491:
1487:
1468:
1464:
1393:pharmacokinetic
1384:
1380:
1353:
1340:
1336:
1332:
1328:
1320:
1313:pharmacodynamic
1308:
1304:
1279:, reduction of
1258:
1247:partial agonist
1238:
1215:
1210:
1145:cytochrome P450
1084:
1068:
1028:
1024:
1015:
995:
989:
976:
968:
964:
949:
946:
944:Available forms
891:hyperthyroidism
887:
878:
855:
840:bronchial spasm
761:
759:
754:
751:
746:
741:
740:
729:
726:
721:
720:
708:Racemic mixture
697:
672:
662:
656:
650:
644:
605:
581:
573:
553:
533:
513:
493:
473:
453:
433:
416:
408:
388:
385:
376:
375:
326:
315:
314:: <5 minutes
311:
302:Onset of action
282:Protein binding
272:Bioavailability
264:Pharmacokinetic
258:
249:
210:
180:
152:
145:
126:
119:
17:
12:
11:
5:
6338:
6328:
6327:
6322:
6317:
6312:
6307:
6302:
6297:
6282:
6281:
6258:
6257:
6255:
6254:
6244:
6233:
6230:
6229:
6227:
6226:
6221:
6215:
6213:
6209:
6208:
6206:
6205:
6200:
6195:
6190:
6185:
6179:
6177:
6171:
6170:
6168:
6167:
6162:
6157:
6152:
6147:
6142:
6137:
6132:
6127:
6122:
6117:
6112:
6107:
6102:
6097:
6092:
6087:
6082:
6077:
6072:
6067:
6062:
6057:
6052:
6047:
6042:
6037:
6032:
6027:
6022:
6017:
6012:
6007:
6002:
5997:
5992:
5987:
5982:
5977:
5972:
5967:
5962:
5957:
5952:
5947:
5942:
5937:
5932:
5927:
5922:
5920:Andexanet alfa
5917:
5912:
5906:
5904:
5900:
5899:
5892:
5891:
5884:
5877:
5869:
5860:
5859:
5857:
5856:
5847:
5838:
5829:
5820:
5811:
5802:
5789:
5786:
5785:
5782:
5781:
5779:
5778:
5773:
5768:
5763:
5758:
5753:
5748:
5743:
5738:
5733:
5728:
5723:
5718:
5713:
5708:
5703:
5698:
5693:
5688:
5683:
5678:
5673:
5668:
5663:
5658:
5653:
5648:
5643:
5638:
5633:
5628:
5623:
5618:
5613:
5608:
5603:
5598:
5593:
5588:
5583:
5578:
5573:
5568:
5563:
5558:
5553:
5548:
5543:
5538:
5533:
5528:
5523:
5518:
5513:
5508:
5503:
5498:
5493:
5488:
5483:
5478:
5473:
5468:
5463:
5458:
5453:
5448:
5443:
5438:
5433:
5428:
5423:
5418:
5413:
5411:Dexpropranolol
5408:
5403:
5398:
5393:
5388:
5383:
5378:
5373:
5368:
5363:
5358:
5353:
5348:
5343:
5338:
5333:
5328:
5323:
5318:
5313:
5308:
5303:
5298:
5293:
5288:
5283:
5278:
5273:
5268:
5263:
5258:
5253:
5248:
5243:
5238:
5233:
5228:
5223:
5218:
5213:
5207:
5205:
5201:
5200:
5198:
5197:
5192:
5187:
5182:
5177:
5172:
5167:
5162:
5157:
5152:
5147:
5142:
5137:
5132:
5127:
5122:
5117:
5112:
5107:
5102:
5097:
5092:
5087:
5082:
5080:Norepinephrine
5077:
5072:
5067:
5062:
5057:
5052:
5047:
5045:Levosalbutamol
5042:
5034:
5032:-Phenylalanine
5026:
5018:
5013:
5008:
5003:
4998:
4993:
4988:
4983:
4978:
4973:
4968:
4963:
4958:
4953:
4948:
4943:
4934:
4929:
4924:
4919:
4914:
4905:
4900:
4895:
4890:
4885:
4880:
4875:
4870:
4865:
4860:
4855:
4850:
4845:
4840:
4835:
4830:
4825:
4820:
4815:
4809:
4807:
4800:
4794:
4793:
4790:
4789:
4787:
4786:
4781:
4766:chlorpromazine
4759:
4754:
4749:
4744:
4739:
4734:
4729:
4724:
4719:
4714:
4709:
4704:
4699:
4694:
4689:
4684:
4679:
4674:
4669:
4664:
4659:
4654:
4649:
4644:
4639:
4634:
4629:
4624:
4602:
4560:
4555:
4550:
4545:
4540:
4534:
4532:
4528:
4527:
4525:
4524:
4522:Xylometazoline
4519:
4514:
4509:
4504:
4499:
4494:
4489:
4484:
4479:
4474:
4469:
4464:
4459:
4454:
4449:
4444:
4439:
4434:
4432:Norepinephrine
4429:
4424:
4419:
4414:
4409:
4404:
4399:
4394:
4389:
4381:
4379:-Phenylalanine
4373:
4365:
4360:
4355:
4350:
4345:
4340:
4335:
4330:
4325:
4316:
4311:
4306:
4301:
4296:
4291:
4282:
4277:
4272:
4267:
4262:
4257:
4252:
4247:
4241:
4239:
4232:
4228:
4223:
4222:
4219:
4218:
4216:
4215:
4210:
4205:
4200:
4185:chlorpromazine
4178:
4173:
4147:
4129:
4124:
4119:
4114:
4109:
4104:
4099:
4094:
4089:
4084:
4079:
4074:
4069:
4044:
4039:
4034:
4029:
4024:
4019:
4014:
4009:
4004:
3999:
3994:
3989:
3984:
3979:
3974:
3969:
3964:
3959:
3954:
3949:
3944:
3939:
3934:
3904:
3899:
3894:
3889:
3884:
3879:
3874:
3844:
3839:
3813:
3808:
3803:
3798:
3793:
3788:
3782:
3780:
3776:
3775:
3773:
3772:
3770:Xylometazoline
3767:
3762:
3757:
3752:
3747:
3742:
3737:
3732:
3727:
3725:Norepinephrine
3722:
3717:
3712:
3707:
3702:
3697:
3692:
3684:
3682:-Phenylalanine
3676:
3668:
3663:
3658:
3653:
3648:
3643:
3638:
3633:
3624:
3619:
3614:
3609:
3604:
3595:
3590:
3585:
3580:
3575:
3569:
3567:
3560:
3556:
3551:
3550:
3540:
3539:
3532:
3525:
3517:
3508:
3507:
3504:
3503:
3502:
3501:
3498:
3487:
3481:
3475:
3474:
3471:
3470:
3468:
3467:
3462:
3457:
3451:
3449:
3444:
3439:
3438:
3436:
3435:
3429:
3427:
3422:
3417:
3416:
3414:
3413:
3408:
3403:
3398:
3393:
3388:
3383:
3378:
3373:
3368:
3363:
3358:
3353:
3347:
3345:
3340:
3335:
3334:
3332:
3331:
3326:
3321:
3316:
3311:
3302:
3297:
3292:
3287:
3282:
3277:
3272:
3267:
3262:
3256:
3254:
3247:
3246:
3234:
3233:
3226:
3219:
3211:
3203:
3202:
3173:(6): 325–332.
3153:
3113:
3102:. 21 July 2022
3087:
3061:
3036:
2978:
2957:(9): 603–610.
2934:
2911:(6): 414–423.
2895:
2877:
2854:
2827:
2800:
2789:(4): 537–541.
2772:
2753:(4): 251–254.
2737:
2716:(4): 791–796.
2696:
2656:
2621:
2580:
2538:
2508:
2493:
2468:Anesthesiology
2458:
2439:(23): 1903–7.
2423:
2382:
2333:
2290:
2247:
2220:(9): 1879–86.
2203:
2173:
2138:
2127:on 11 May 2008
2107:
2049:
2019:
1980:
1955:
1925:
1897:
1890:
1870:
1840:
1833:
1811:
1782:(1): e000230.
1762:
1711:
1666:
1579:
1549:
1548:
1546:
1543:
1516:
1513:
1511:
1508:
1499:
1496:
1418:side effects.
1352:
1349:
1277:cardiac output
1256:
1236:
1221:, that is, an
1217:Atenolol is a
1214:
1211:
1209:
1206:
1163:cardiovascular
1135:without being
1083:
1080:
1066:
1026:
1022:
1014:
1011:
988:
985:
945:
942:
936:diuretics and
926:ACE inhibitors
886:
883:
866:and workload.
853:
799:. It is taken
768:
767:
756:
755:
753:
752:
749:
747:
744:
736:
735:
734:
731:
730:
728:
727:
724:
716:
715:
714:
711:
710:
705:
699:
698:
696:
695:
687:
685:
677:
676:
670:
664:
663:
660:
654:
648:
642:
637:
631:
630:
626:
625:
615:
607:
606:
604:
603:
590:
588:
575:
574:
572:
571:
563:
561:
555:
554:
552:
551:
543:
541:
535:
534:
532:
531:
523:
521:
515:
514:
512:
511:
503:
501:
495:
494:
492:
491:
483:
481:
475:
474:
472:
471:
463:
461:
455:
454:
452:
451:
443:
441:
435:
434:
432:
431:
423:
421:
410:
409:
407:
406:
398:
396:
390:
389:
387:
386:
379:
371:
370:
369:
366:
365:
361:
360:
350:
344:
343:
340:
334:
333:
330:
321:
320:
304:
298:
297:
294:
288:
287:
284:
278:
277:
274:
268:
267:
260:
259:
257:
256:
253:
239:
225:
223:
217:
216:
212:
211:
209:
208:
195:
193:
187:
186:
178:
171:
165:
164:
155:
153:administration
147:
146:
144:
143:
141:
131:
129:
121:
120:
118:
117:
99:
97:
91:
90:
83:
77:
76:
69:
59:
58:
55:
49:
48:
44:
43:
35:
34:
15:
9:
6:
4:
3:
2:
6337:
6326:
6323:
6321:
6318:
6316:
6313:
6311:
6308:
6306:
6305:Beta blockers
6303:
6301:
6298:
6296:
6293:
6292:
6290:
6280:
6270:
6269:
6266:
6253:
6245:
6243:
6235:
6234:
6231:
6225:
6222:
6220:
6217:
6216:
6214:
6210:
6204:
6201:
6199:
6196:
6194:
6191:
6189:
6186:
6184:
6181:
6180:
6178:
6172:
6166:
6163:
6161:
6158:
6156:
6153:
6151:
6148:
6146:
6143:
6141:
6138:
6136:
6133:
6131:
6128:
6126:
6123:
6121:
6118:
6116:
6113:
6111:
6108:
6106:
6103:
6101:
6098:
6096:
6093:
6091:
6088:
6086:
6083:
6081:
6078:
6076:
6073:
6071:
6068:
6066:
6063:
6061:
6058:
6056:
6053:
6051:
6048:
6046:
6043:
6041:
6038:
6036:
6033:
6031:
6028:
6026:
6023:
6021:
6018:
6016:
6013:
6011:
6008:
6006:
6003:
6001:
5998:
5996:
5993:
5991:
5988:
5986:
5983:
5981:
5978:
5976:
5975:Dapagliflozin
5973:
5971:
5968:
5966:
5963:
5961:
5958:
5956:
5953:
5951:
5948:
5946:
5943:
5941:
5938:
5936:
5933:
5931:
5930:Asfotase alfa
5928:
5926:
5923:
5921:
5918:
5916:
5913:
5911:
5910:Acalabrutinib
5908:
5907:
5905:
5901:
5897:
5890:
5885:
5883:
5878:
5876:
5871:
5870:
5867:
5854:
5853:
5848:
5845:
5844:
5839:
5836:
5835:
5830:
5827:
5826:
5821:
5818:
5817:
5816:Serotonergics
5812:
5809:
5808:
5807:Dopaminergics
5803:
5800:
5799:
5796:
5791:
5790:
5787:
5777:
5774:
5772:
5769:
5767:
5764:
5762:
5759:
5757:
5754:
5752:
5749:
5747:
5744:
5742:
5739:
5737:
5734:
5732:
5729:
5727:
5724:
5722:
5719:
5717:
5714:
5712:
5709:
5707:
5704:
5702:
5699:
5697:
5694:
5692:
5689:
5687:
5684:
5682:
5679:
5677:
5674:
5672:
5669:
5667:
5664:
5662:
5659:
5657:
5654:
5652:
5649:
5647:
5644:
5642:
5639:
5637:
5634:
5632:
5629:
5627:
5624:
5622:
5619:
5617:
5614:
5612:
5609:
5607:
5604:
5602:
5599:
5597:
5594:
5592:
5589:
5587:
5584:
5582:
5579:
5577:
5574:
5572:
5569:
5567:
5564:
5562:
5561:Levobetaxolol
5559:
5557:
5554:
5552:
5549:
5547:
5544:
5542:
5539:
5537:
5534:
5532:
5529:
5527:
5524:
5522:
5519:
5517:
5514:
5512:
5509:
5507:
5504:
5502:
5499:
5497:
5494:
5492:
5489:
5487:
5484:
5482:
5479:
5477:
5474:
5472:
5469:
5467:
5464:
5462:
5459:
5457:
5454:
5452:
5449:
5447:
5444:
5442:
5439:
5437:
5434:
5432:
5429:
5427:
5424:
5422:
5419:
5417:
5414:
5412:
5409:
5407:
5404:
5402:
5401:Cyanopindolol
5399:
5397:
5394:
5392:
5389:
5387:
5384:
5382:
5379:
5377:
5374:
5372:
5369:
5367:
5364:
5362:
5359:
5357:
5354:
5352:
5349:
5347:
5344:
5342:
5339:
5337:
5334:
5332:
5329:
5327:
5324:
5322:
5319:
5317:
5314:
5312:
5309:
5307:
5304:
5302:
5299:
5297:
5294:
5292:
5289:
5287:
5284:
5282:
5279:
5277:
5274:
5272:
5269:
5267:
5264:
5262:
5259:
5257:
5254:
5252:
5249:
5247:
5244:
5242:
5239:
5237:
5234:
5232:
5229:
5227:
5224:
5222:
5219:
5217:
5214:
5212:
5209:
5208:
5206:
5202:
5196:
5193:
5191:
5188:
5186:
5183:
5181:
5178:
5176:
5173:
5171:
5168:
5166:
5163:
5161:
5158:
5156:
5153:
5151:
5148:
5146:
5143:
5141:
5138:
5136:
5133:
5131:
5128:
5126:
5123:
5121:
5118:
5116:
5113:
5111:
5108:
5106:
5103:
5101:
5098:
5096:
5093:
5091:
5088:
5086:
5085:Orciprenaline
5083:
5081:
5078:
5076:
5073:
5071:
5068:
5066:
5063:
5061:
5058:
5056:
5053:
5051:
5048:
5046:
5043:
5041:
5035:
5033:
5027:
5025:
5019:
5017:
5014:
5012:
5009:
5007:
5004:
5002:
4999:
4997:
4994:
4992:
4989:
4987:
4986:Hexoprenaline
4984:
4982:
4979:
4977:
4974:
4972:
4969:
4967:
4964:
4962:
4959:
4957:
4954:
4952:
4949:
4947:
4944:
4942:
4935:
4933:
4930:
4928:
4925:
4923:
4920:
4918:
4915:
4913:
4911:
4906:
4904:
4901:
4899:
4896:
4894:
4891:
4889:
4886:
4884:
4881:
4879:
4876:
4874:
4871:
4869:
4866:
4864:
4861:
4859:
4856:
4854:
4851:
4849:
4846:
4844:
4841:
4839:
4836:
4834:
4831:
4829:
4826:
4824:
4821:
4819:
4816:
4814:
4811:
4810:
4808:
4804:
4801:
4799:
4795:
4785:
4782:
4779:
4775:
4771:
4767:
4763:
4760:
4758:
4755:
4753:
4750:
4748:
4745:
4743:
4740:
4738:
4735:
4733:
4730:
4728:
4725:
4723:
4720:
4718:
4715:
4713:
4710:
4708:
4705:
4703:
4700:
4698:
4695:
4693:
4690:
4688:
4685:
4683:
4680:
4678:
4675:
4673:
4670:
4668:
4665:
4663:
4660:
4658:
4655:
4653:
4650:
4648:
4647:Esmirtazapine
4645:
4643:
4640:
4638:
4635:
4633:
4630:
4628:
4625:
4622:
4618:
4614:
4610:
4606:
4603:
4600:
4596:
4592:
4588:
4584:
4580:
4576:
4572:
4571:brexpiprazole
4568:
4564:
4561:
4559:
4556:
4554:
4551:
4549:
4546:
4544:
4541:
4539:
4536:
4535:
4533:
4529:
4523:
4520:
4518:
4515:
4513:
4510:
4508:
4505:
4503:
4500:
4498:
4495:
4493:
4490:
4488:
4485:
4483:
4480:
4478:
4475:
4473:
4470:
4468:
4465:
4463:
4460:
4458:
4455:
4453:
4450:
4448:
4445:
4443:
4440:
4438:
4437:Oxymetazoline
4435:
4433:
4430:
4428:
4425:
4423:
4420:
4418:
4415:
4413:
4410:
4408:
4405:
4403:
4400:
4398:
4395:
4393:
4390:
4388:
4382:
4380:
4374:
4372:
4366:
4364:
4361:
4359:
4356:
4354:
4351:
4349:
4346:
4344:
4341:
4339:
4336:
4334:
4331:
4329:
4326:
4324:
4317:
4315:
4312:
4310:
4307:
4305:
4302:
4300:
4297:
4295:
4292:
4290:
4288:
4283:
4281:
4278:
4276:
4273:
4271:
4268:
4266:
4265:Apraclonidine
4263:
4261:
4258:
4256:
4253:
4251:
4248:
4246:
4243:
4242:
4240:
4236:
4233:
4231:
4224:
4214:
4211:
4209:
4206:
4204:
4201:
4198:
4194:
4190:
4186:
4182:
4179:
4177:
4174:
4171:
4167:
4163:
4159:
4155:
4154:amitriptyline
4151:
4148:
4145:
4141:
4137:
4133:
4130:
4128:
4125:
4123:
4120:
4118:
4115:
4113:
4110:
4108:
4105:
4103:
4100:
4098:
4095:
4093:
4090:
4088:
4085:
4083:
4080:
4078:
4075:
4073:
4070:
4067:
4066:triazoledione
4063:
4059:
4055:
4051:
4048:
4045:
4043:
4040:
4038:
4035:
4033:
4030:
4028:
4025:
4023:
4020:
4018:
4015:
4013:
4010:
4008:
4005:
4003:
4000:
3998:
3995:
3993:
3990:
3988:
3985:
3983:
3980:
3978:
3975:
3973:
3970:
3968:
3965:
3963:
3960:
3958:
3955:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3932:
3928:
3924:
3920:
3916:
3912:
3908:
3905:
3903:
3900:
3898:
3895:
3893:
3890:
3888:
3885:
3883:
3880:
3878:
3875:
3872:
3868:
3864:
3860:
3856:
3852:
3848:
3847:Beta blockers
3845:
3843:
3840:
3837:
3833:
3829:
3825:
3821:
3820:brexpiprazole
3817:
3814:
3812:
3809:
3807:
3804:
3802:
3799:
3797:
3794:
3792:
3789:
3787:
3784:
3783:
3781:
3777:
3771:
3768:
3766:
3763:
3761:
3758:
3756:
3753:
3751:
3748:
3746:
3743:
3741:
3740:Phenylephrine
3738:
3736:
3735:Oxymetazoline
3733:
3731:
3728:
3726:
3723:
3721:
3718:
3716:
3713:
3711:
3708:
3706:
3703:
3701:
3698:
3696:
3693:
3691:
3685:
3683:
3677:
3675:
3669:
3667:
3666:Isometheptene
3664:
3662:
3659:
3657:
3654:
3652:
3649:
3647:
3644:
3642:
3639:
3637:
3634:
3632:
3625:
3623:
3620:
3618:
3615:
3613:
3610:
3608:
3605:
3603:
3601:
3596:
3594:
3591:
3589:
3586:
3584:
3581:
3579:
3576:
3574:
3571:
3570:
3568:
3564:
3561:
3559:
3552:
3548:
3545:
3538:
3533:
3531:
3526:
3524:
3519:
3518:
3515:
3499:
3497:
3494:
3493:
3491:
3488:
3485:
3482:
3480:
3477:
3476:
3472:
3466:
3463:
3461:
3458:
3456:
3453:
3452:
3450:
3447:
3440:
3434:
3431:
3430:
3428:
3425:
3418:
3412:
3409:
3407:
3404:
3402:
3399:
3397:
3394:
3392:
3389:
3387:
3384:
3382:
3379:
3377:
3374:
3372:
3369:
3367:
3364:
3362:
3359:
3357:
3354:
3352:
3349:
3348:
3346:
3343:
3336:
3330:
3327:
3325:
3322:
3320:
3317:
3315:
3312:
3310:
3306:
3303:
3301:
3298:
3296:
3293:
3291:
3288:
3286:
3283:
3281:
3278:
3276:
3273:
3271:
3268:
3266:
3263:
3261:
3258:
3257:
3255:
3252:
3248:
3243:
3239:
3238:Beta blockers
3232:
3227:
3225:
3220:
3218:
3213:
3212:
3209:
3198:
3194:
3189:
3184:
3180:
3176:
3172:
3168:
3164:
3157:
3141:
3137:
3136:
3131:
3124:
3122:
3120:
3118:
3101:
3097:
3096:"DL-Atenolol"
3091:
3075:
3071:
3065:
3050:
3046:
3040:
3032:
3028:
3023:
3018:
3013:
3008:
3004:
3000:
2996:
2989:
2987:
2985:
2983:
2974:
2970:
2965:
2960:
2956:
2952:
2948:
2941:
2939:
2931:
2926:
2922:
2918:
2914:
2910:
2906:
2899:
2892:
2880:
2874:
2870:
2869:
2861:
2859:
2850:
2846:
2843:(5): 376–81.
2842:
2838:
2831:
2823:
2819:
2815:
2811:
2804:
2796:
2792:
2788:
2784:
2776:
2768:
2764:
2760:
2756:
2752:
2748:
2741:
2733:
2729:
2724:
2719:
2715:
2711:
2707:
2700:
2693:
2688:
2684:
2680:
2676:
2672:
2668:
2660:
2652:
2648:
2644:
2640:
2636:
2632:
2625:
2618:
2614:
2610:
2606:
2602:
2598:
2594:
2587:
2585:
2577:
2572:
2568:
2564:
2560:
2556:
2552:
2545:
2543:
2523:
2517:
2515:
2513:
2504:
2497:
2489:
2485:
2481:
2477:
2473:
2469:
2462:
2454:
2450:
2446:
2442:
2438:
2434:
2427:
2419:
2415:
2410:
2405:
2401:
2397:
2393:
2386:
2378:
2374:
2369:
2364:
2360:
2356:
2352:
2348:
2344:
2337:
2329:
2325:
2321:
2317:
2313:
2309:
2305:
2301:
2294:
2286:
2282:
2278:
2274:
2270:
2266:
2262:
2258:
2251:
2243:
2239:
2235:
2231:
2227:
2223:
2219:
2215:
2207:
2192:
2188:
2182:
2180:
2178:
2169:
2165:
2161:
2157:
2153:
2149:
2142:
2126:
2122:
2118:
2111:
2104:
2099:
2095:
2090:
2085:
2081:
2077:
2073:
2069:
2065:
2058:
2056:
2054:
2037:
2033:
2029:
2023:
2007:
2003:
1999:
1995:
1991:
1984:
1969:
1965:
1959:
1943:
1939:
1935:
1929:
1920:
1915:
1911:
1907:
1901:
1893:
1891:9783527607495
1887:
1883:
1882:
1874:
1858:
1854:
1850:
1844:
1836:
1834:9780857113382
1830:
1826:
1820:
1818:
1816:
1807:
1803:
1798:
1793:
1789:
1785:
1781:
1777:
1773:
1766:
1758:
1754:
1749:
1744:
1739:
1734:
1730:
1726:
1722:
1715:
1699:
1695:
1691:
1685:
1683:
1681:
1679:
1677:
1675:
1673:
1671:
1654:
1650:
1646:
1640:
1638:
1636:
1634:
1632:
1630:
1628:
1626:
1624:
1622:
1620:
1618:
1616:
1614:
1612:
1610:
1608:
1606:
1604:
1602:
1600:
1598:
1596:
1594:
1592:
1590:
1588:
1586:
1584:
1568:
1564:
1560:
1554:
1550:
1542:
1540:
1535:
1534:beta blockers
1531:
1530:beta blockers
1527:
1522:
1507:
1505:
1495:
1485:
1482:
1478:
1474:
1462:
1457:
1455:
1451:
1448:
1444:
1440:
1436:
1432:
1428:
1424:
1419:
1417:
1413:
1409:
1405:
1404:lipophilicity
1401:
1396:
1394:
1390:
1387:minutes with
1378:
1374:
1370:
1366:
1362:
1358:
1348:
1346:
1326:
1318:
1314:
1302:
1298:
1294:
1293:isoproterenol
1290:
1286:
1282:
1278:
1274:
1271:
1267:
1262:
1260:
1252:
1249:activity) or
1248:
1244:
1240:
1232:
1228:
1224:
1220:
1205:
1202:
1198:
1194:
1190:
1187:
1186:non-selective
1182:
1180:
1176:
1172:
1168:
1164:
1159:
1157:
1153:
1149:
1146:
1142:
1138:
1134:
1131:
1126:
1124:
1120:
1116:
1112:
1108:
1104:
1100:
1096:
1092:
1088:
1079:
1076:
1072:
1064:
1060:
1056:
1052:
1048:
1044:
1043:heart failure
1040:
1036:
1032:
1020:
1010:
1008:
1004:
999:
994:
984:
982:
974:
973:chlortalidone
962:
958:
955:
941:
939:
935:
931:
927:
922:
920:
916:
912:
908:
904:
900:
896:
892:
882:
876:
872:
867:
865:
861:
857:
849:
848:breastfeeding
845:
841:
837:
833:
829:
825:
824:heart failure
821:
820:feeling tired
817:
812:
810:
806:
802:
798:
794:
790:
786:
782:
778:
774:
764:
757:
748:
743:
742:
739:
732:
723:
722:
719:
712:
709:
706:
704:
700:
693:
689:
688:
686:
683:
678:
671:
669:
665:
638:
636:
632:
627:
623:
619:
616:
614:
612:ECHA InfoCard
608:
600:
596:
595:DTXSID2022628
592:
591:
589:
580:
576:
569:
565:
564:
562:
560:
556:
549:
545:
544:
542:
540:
536:
529:
525:
524:
522:
520:
516:
509:
505:
504:
502:
500:
496:
489:
485:
484:
482:
480:
476:
469:
465:
464:
462:
460:
456:
449:
445:
444:
442:
440:
436:
429:
425:
424:
422:
415:
411:
404:
400:
399:
397:
395:
391:
383:
378:
377:
374:
367:
362:
354:
351:
349:
345:
341:
339:
335:
331:
329:
322:
318:
310:
305:
303:
299:
295:
293:
289:
285:
283:
279:
275:
273:
269:
265:
261:
254:
252:
240:
237:
227:
226:
224:
222:
218:
213:
205:
200:
197:
196:
194:
192:
188:
185:
182:
175:
172:
170:
166:
163:
159:
156:
154:
148:
142:
133:
132:
130:
128:
122:
115:
110:
101:
100:
98:
96:
92:
88:
84:
82:
78:
74:
70:
68:
64:
60:
56:
54:
50:
47:Clinical data
45:
41:
36:
32:
27:
19:
6219:Tom McKillop
6165:Zolmitriptan
6155:Ximelagatran
6085:Rosuvastatin
5995:Esomeprazole
5945:Bicalutamide
5940:Benralizumab
5934:
5850:
5841:
5832:
5823:
5814:
5805:
5794:
5793:
5586:Metipranolol
5571:Levomoprolol
5516:Idropranolol
5260:
5011:Isoprenaline
4909:
4833:Arformoterol
4778:thioridazine
4770:fluphenazine
4742:Spiroxatrine
4702:Phentolamine
4621:tandospirone
4587:paliperidone
4477:Tasipimidine
4457:Rezatomidine
4402:Medetomidine
4286:
4197:thioridazine
4189:fluphenazine
4170:trimipramine
4158:clomipramine
4042:Phentolamine
3911:acetergamine
3887:Corynanthine
3599:
3355:
3309:Iodopindolol
3170:
3166:
3156:
3144:. Retrieved
3135:The Atlantic
3133:
3104:. Retrieved
3099:
3090:
3078:. Retrieved
3073:
3064:
3052:. Retrieved
3048:
3039:
3002:
2998:
2954:
2950:
2928:
2908:
2904:
2898:
2889:
2882:. Retrieved
2867:
2840:
2836:
2830:
2816:(2): 85–91.
2813:
2809:
2803:
2786:
2782:
2775:
2750:
2746:
2740:
2713:
2709:
2699:
2690:
2670:
2666:
2659:
2634:
2630:
2624:
2616:
2596:
2592:
2574:
2554:
2550:
2529:. Retrieved
2502:
2496:
2474:(1): 204–7.
2471:
2467:
2461:
2436:
2432:
2426:
2399:
2395:
2385:
2350:
2346:
2336:
2303:
2299:
2293:
2260:
2256:
2250:
2217:
2213:
2206:
2194:. Retrieved
2190:
2154:(1): 10–27.
2151:
2147:
2141:
2129:. Retrieved
2125:the original
2110:
2101:
2071:
2067:
2040:. Retrieved
2031:
2022:
2010:. Retrieved
1993:
1983:
1971:. Retrieved
1967:
1958:
1946:. Retrieved
1937:
1928:
1919:10665/345533
1909:
1900:
1880:
1873:
1861:. Retrieved
1852:
1843:
1824:
1779:
1775:
1765:
1728:
1724:
1714:
1702:. Retrieved
1693:
1657:. Retrieved
1648:
1570:. Retrieved
1562:
1553:
1518:
1501:
1458:
1420:
1397:
1354:
1263:
1219:beta blocker
1216:
1208:Pharmacology
1201:hypertensive
1183:
1175:hypertension
1171:amphetamines
1160:
1127:
1119:indomethacin
1103:disopyramide
1087:Interactions
1085:
1082:Interactions
1071:hexoprenalin
1047:hypoglycemia
1017:Symptoms of
1016:
1000:
996:
993:Beta blocker
987:Side effects
963:of 50 or 100
947:
923:
895:hypertension
888:
885:Medical uses
868:
816:side effects
813:
777:beta blocker
772:
771:
760:
381:
342:>24 hours
325:Elimination
319:: <1 hour
221:Legal status
215:Legal status
95:License data
18:
6160:Zafirlukast
6115:Selumetinib
6105:Saxagliptin
6100:Savolitinib
6080:Roflumilast
6075:Ravulizumab
6060:Palivizumab
6055:Osimertinib
6040:Motavizumab
6010:Fulvestrant
5970:Candesartan
5925:Anifrolumab
5915:Anastrozole
5896:AstraZeneca
5711:Spirendolol
5686:Propranolol
5681:Propafenone
5676:Pronethalol
5566:Levobunolol
5541:Isoxaprolol
5526:Indopanolol
5511:ICI-118,551
5476:Eugenodilol
5461:Ersentilide
5441:Draquinolol
5436:Diprafenone
5406:Dalbraminol
5386:Cicloprolol
5361:Carpindolol
5346:Butofilolol
5291:Bornaprolol
5236:Alprenoxime
5204:Antagonists
5165:Tulobuterol
5160:Tretoquinol
5155:Terbutaline
5115:Ractopamine
5110:Prenalterol
5016:Isoxsuprine
5001:Indacaterol
4971:Eugenodilol
4961:Etilevodopa
4946:Epinephrine
4937:Droxidopa (
4917:Dipivefrine
4888:Clenbuterol
4732:Setiptiline
4722:Rauwolscine
4697:Pardoprunox
4687:Mirtazapine
4652:Fenmetozole
4595:risperidone
4558:Atipamezole
4531:Antagonists
4487:Tiamenidine
4482:Tetryzoline
4462:Rilmenidine
4427:Naphazoline
4363:Guanoxabenz
4338:Epinephrine
4328:Etilevodopa
4319:Droxidopa (
4309:Dipivefrine
4270:Brimonidine
4140:maprotiline
4017:Pardoprunox
4012:Niguldipine
3972:Mepiprazole
3947:Hydroxyzine
3937:Etoperidone
3927:nicergoline
3897:Domesticine
3892:Dapiprazole
3867:eugenodilol
3842:Benoxathian
3836:risperidone
3801:Anisodamine
3779:Antagonists
3760:Tiamenidine
3755:Tetryzoline
3720:Naphazoline
3705:Methoxamine
3700:Metaraminol
3646:Etilevodopa
3636:Epinephrine
3627:Droxidopa (
3617:Dipivefrine
3578:Amidephrine
3486:from market
3314:Propranolol
2783:Saudi Med J
2667:Circulation
2012:5 September
1863:23 December
1704:23 December
1659:20 November
1490:mL/min/1.73
1445:mainly via
1431:propranolol
1343:hours. The
1291:induced by
1289:tachycardia
1179:tachycardia
1165:effects of
1137:metabolized
1035:hypotension
1031:bradycardia
961:combination
675: g·mol
618:100.044.941
364:Identifiers
359:, 50% oral)
162:intravenous
81:MedlinePlus
53:Trade names
6295:Acetamides
6289:Categories
6145:Vandetanib
6130:Ticagrelor
6090:Roxadustat
6070:Quetiapine
6050:Omeprazole
6035:Metoprolol
5990:Eculizumab
5985:Durvalumab
5955:Budesonide
5776:Xipranolol
5766:Toliprolol
5756:Tiprenolol
5741:Tienoxolol
5736:Tertatolol
5721:Sulfinalol
5701:Soquinolol
5696:Ronactolol
5671:Procinolol
5666:Primidolol
5651:Penbutolol
5631:Pacrinolol
5626:Oxprenolol
5621:Nipradilol
5591:Metoprolol
5581:Mepindolol
5576:Medroxalol
5546:Isamoltane
5536:Iprocrolol
5496:Flusoxolol
5486:Falintolol
5466:Esatenolol
5416:Diacetolol
5396:Cloranolol
5376:Celiprolol
5371:Carvedilol
5351:Capsinolol
5336:Butaxamine
5331:Bupranolol
5321:Bunitrolol
5301:Bucindolol
5296:Brefonalol
5286:Bopindolol
5281:Bisoprolol
5276:Bevantolol
5256:Arotinolol
5241:Amosulalol
5231:Alprenolol
5211:Acebutolol
5190:Zilpaterol
5175:Vilanterol
5150:Solabegron
5145:Salmeterol
5140:Salbutamol
5125:Reproterol
5120:Procaterol
5105:Pirbuterol
5090:Oxyfedrine
5075:Mirabegron
5070:Methyldopa
5060:Melevodopa
5050:Lubabegron
5006:Isoetarine
4991:Higenamine
4981:Formoterol
4956:Etilefrine
4951:Etafedrine
4932:Dopexamine
4922:Dobutamine
4903:Denopamine
4898:Corbadrine
4878:Carmoterol
4873:Carbuterol
4863:Broxaterol
4858:Bitolterol
4848:Bambuterol
4838:Arotinolol
4828:Arbutamine
4818:Alifedrine
4813:Abediterol
4757:Tolazoline
4747:Sunepitron
4737:Spegatrine
4727:Rotigotine
4667:Ketanserin
4657:Fluparoxan
4637:Cirazoline
4632:Buflomedil
4617:ipsapirone
4605:Azapirones
4591:quetiapine
4583:olanzapine
4579:lurasidone
4553:Aptazapine
4548:Amesergide
4497:Tolonidine
4492:Tizanidine
4472:Talipexole
4467:Romifidine
4422:Moxonidine
4412:Methyldopa
4407:Melevodopa
4397:Lofexidine
4358:Guanfacine
4343:Etilefrine
4333:Ergotamine
4294:Detomidine
4280:Corbadrine
4176:Trimazosin
4166:imipramine
4127:Tolazoline
4122:Tiodazosin
4112:Tamsulosin
4107:Talipexole
4097:Spegatrine
4082:Quinazosin
4058:nefazodone
4032:Phendioxan
4022:Pelanserin
4007:Niaprazine
4002:Neldazosin
3992:Naftopidil
3987:Moxisylyte
3957:Ketanserin
3942:Fenspiride
3915:ergotamine
3877:Buflomedil
3863:carvedilol
3859:arotinolol
3855:amosulalol
3832:quetiapine
3828:olanzapine
3791:Ajmalicine
3750:Synephrine
3730:Octopamine
3710:Methyldopa
3695:Melevodopa
3661:Indanidine
3641:Etilefrine
3593:Corbadrine
3588:Cirazoline
3547:modulators
3460:Carvedilol
3455:Arotinolol
3433:Butaxamine
3426:-selective
3396:Metoprolol
3376:Celiprolol
3371:Bisoprolol
3366:Bevantolol
3351:Acebutolol
3344:-selective
3324:Tertatolol
3300:Penbutolol
3295:Oxprenolol
3285:Mepindolol
3280:Cloranolol
3270:Bupranolol
3265:Bopindolol
3260:Alprenolol
3100:ChemSpider
3045:"Atenolol"
3005:(2): 155.
2300:The Lancet
2028:"Atenolol"
1994:StatPearls
1990:"Atenolol"
1776:Open Heart
1731:: 919256.
1572:22 October
1545:References
1481:creatinine
1443:eliminated
1435:metoprolol
1423:metabolism
1365:intestines
1357:absorption
1273:heart rate
1223:antagonist
1193:phenelzine
1173:, such as
1152:inhibitors
1130:eliminated
1107:amiodarone
1075:salbutamol
1063:dobutamine
1025:and also β
991:See also:
864:heart rate
832:depression
680:3D model (
668:Molar mass
548:CHEBI:2904
508:50VV3VW0TI
479:ChemSpider
439:IUPHAR/BPS
403:29122-68-7
394:CAS Number
373:IUPAC name
292:Metabolism
184:antagonist
169:Drug class
6198:MedImmune
6150:Vaxzevria
6125:Tamoxifen
6025:Goserelin
6015:Gefitinib
6000:Exenatide
5795:See also:
5771:Xibenolol
5761:Tolamolol
5746:Tilisolol
5726:Talinolol
5716:SR 59230A
5691:Ridazolol
5661:Practolol
5641:Pamatolol
5636:Pafenolol
5616:Nifenalol
5611:Nebivolol
5606:Nadoxolol
5556:Landiolol
5551:Labetalol
5521:Indenolol
5491:Flestolol
5481:Exaprolol
5446:Ecastolol
5431:Dilevalol
5391:Cinamolol
5381:Cetamolol
5366:Carteolol
5356:Carazolol
5341:Butidrine
5316:Bufuralol
5311:Bufetolol
5306:Bucumolol
5271:Betaxolol
5266:Befunolol
5246:Ancarolol
5216:Adaprolol
5180:Xamoterol
5135:Ritodrine
5130:Rimiterol
5095:PF-610355
5055:Mabuterol
5040:-Tyrosine
4996:Ibopamine
4976:Fenoterol
4883:Cimaterol
4868:Buphenine
4853:Befunolol
4823:Amibegron
4784:Yohimbine
4752:Terguride
4717:Piribedil
4712:Piperoxan
4682:Mianserin
4627:BRL-44408
4609:buspirone
4575:clozapine
4567:asenapine
4507:Vatinoxan
4447:Piperoxan
4417:Mivazerol
4392:Ibopamine
4387:-Tyrosine
4353:Guanabenz
4275:Clonidine
4213:Zolertine
4144:mianserin
4136:amoxapine
4117:Terazosin
4102:Spiperone
4092:Silodosin
4087:Quinidine
4072:Piperoxan
4062:trazodone
4027:Perlapine
3997:Nantenine
3982:Monatepil
3977:Metazosin
3962:L-765,314
3952:Indoramin
3931:terguride
3907:Ergolines
3902:Doxazosin
3882:Bunazosin
3871:labetalol
3824:clozapine
3811:Atiprosin
3806:Anisodine
3796:Alfuzosin
3786:Abanoquil
3715:Midodrine
3690:-Tyrosine
3656:Ibopamine
3583:Buspirone
3496:Phase III
3484:Withdrawn
3465:Labetalol
3411:Talinolol
3406:Practolol
3401:Nebivolol
3391:Landiolol
3361:Betaxolol
3275:Carteolol
2925:1355-5146
2131:19 August
1973:30 August
1948:30 August
1853:Drugs.com
1694:Drugs.com
1498:Chemistry
1484:clearance
1450:excretion
1231:selective
1111:clonidine
1095:reserpine
1007:Diuretics
981:injection
844:pregnancy
828:dizziness
793:migraines
789:mortality
703:Chirality
355:(>85%
348:Excretion
332:6–7 hours
327:half-life
174:Selective
151:Routes of
125:Pregnancy
73:Monograph
67:Drugs.com
6279:Medicine
6242:Category
6183:Astra AB
6065:Propofol
6045:Olaparib
5935:Atenolol
5903:Products
5656:Pindolol
5646:Pargolol
5596:Moprolol
5471:Esprolol
5456:Ericolol
5451:Epanolol
5261:Atenolol
5226:Afurolol
5221:Adimolol
5195:Zinterol
5170:Vibegron
4927:Dopamine
4893:Colterol
4806:Agonists
4774:loxapine
4672:Lisuride
4662:Idazoxan
4642:Efaroxan
4613:gepirone
4599:zotepine
4543:Adimolol
4517:Xylazine
4502:Urapidil
4314:Dopamine
4238:Agonists
4203:Urapidil
4193:loxapine
4077:Prazosin
3923:lisuride
3851:adimolol
3622:Dopamine
3566:Agonists
3381:Epanolol
3356:Atenolol
3305:Pindolol
3197:30384549
3140:Archived
3106:1 August
3080:1 August
3054:1 August
3031:33572109
2795:15900355
2767:10424315
2687:18427125
2651:25724076
2637:: 1–13.
2613:21810031
2571:14732961
2418:24750981
2377:16754904
2328:34364430
2320:16257341
2285:37044384
2277:17240286
2242:23613019
2234:12195132
2168:17433471
2098:28107561
2036:Archived
2006:Archived
2002:30969666
1968:ClinCalc
1942:Archived
1938:ClinCalc
1908:(2021).
1857:Archived
1806:25821584
1757:24672712
1698:Archived
1696:. AHFS.
1653:Archived
1649:DailyMed
1369:excreted
1281:systolic
1270:exercise
1241:with no
1156:inducers
1059:glucagon
1055:Atropine
1041:, acute
1019:overdose
1013:Overdose
934:thiazide
818:include
773:Atenolol
763:(verify)
568:ChEMBL24
459:DrugBank
191:ATC code
181:receptor
127:category
114:Atenolol
109:DailyMed
23:Atenolol
6252:Commons
6005:FluMist
5751:Timolol
5731:Tazolol
5706:Sotalol
5601:Nadolol
5326:Bunolol
5251:Arnolol
5185:XP21279
4764:(e.g.,
4692:NAN-190
4607:(e.g.,
4565:(e.g.,
4512:XP21279
4260:Amitraz
4208:WB-4101
4183:(e.g.,
4162:doxepin
4152:(e.g.,
4134:(e.g.,
4052:(e.g.,
3909:(e.g.,
3849:(e.g.,
3818:(e.g.,
3765:XP21279
3386:Esmolol
3329:Timolol
3319:Sotalol
3290:Nadolol
3188:6250947
3049:PubChem
3022:7914867
2973:8573662
2849:1684039
2822:2349137
2732:1325059
2488:7605000
2453:9634263
2368:1471831
2089:5369873
1797:4371808
1748:3941231
1439:nadolol
1425:by the
1297:agonist
1266:resting
1245:(i.e.,
1225:of the
1191:(MAOI)
1148:enzymes
1139:by the
1133:renally
957:tablets
858:in the
814:Common
673:266.341
635:Formula
468:DB00335
414:PubChem
296:Minimal
250:WARNING
207:)
201: (
199:C07AB03
140: C
111::
87:a684031
6265:Portal
6212:People
6203:Zeneca
4941:-DOPS)
4323:-DOPS)
4250:4-NEMD
3631:-DOPS)
3479:WHO-EM
3195:
3185:
3029:
3019:
2971:
2923:
2884:8 July
2875:
2847:
2820:
2793:
2765:
2730:
2685:
2649:
2611:
2569:
2531:8 July
2486:
2451:
2416:
2375:
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2326:
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2283:
2275:
2257:Lancet
2240:
2232:
2196:8 July
2166:
2096:
2086:
2000:
1888:
1831:
1804:
1794:
1755:
1745:
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1469:
1465:
1391:. The
1385:
1381:
1341:
1337:
1333:
1329:
1321:
1309:
1305:
1301:reflex
1143:or by
1121:, and
1003:stroke
977:
969:
965:
950:
899:angina
879:
834:, and
801:orally
718:SMILES
559:ChEMBL
528:D00235
276:40–50%
247:
234:
107:
4255:6-FNE
3573:6-FNE
3146:8 May
2525:(PDF)
2324:S2CID
2281:S2CID
2238:S2CID
2042:8 May
1504:log P
1454:urine
1447:renal
1427:liver
1373:feces
1141:liver
1117:like
1093:like
1039:shock
1037:with
860:heart
775:is a
738:InChI
682:JSmol
539:ChEBI
353:Urine
286:6–16%
4843:BAAM
4677:mCPP
4538:1-PP
4452:PS75
3967:mCPP
3193:PMID
3148:2018
3108:2024
3082:2024
3056:2024
3027:PMID
2969:PMID
2921:ISSN
2886:2024
2873:ISBN
2845:PMID
2818:PMID
2791:PMID
2763:PMID
2728:PMID
2683:PMID
2647:PMID
2609:PMID
2567:PMID
2533:2024
2484:PMID
2449:PMID
2433:JAMA
2414:PMID
2373:PMID
2347:CMAJ
2316:PMID
2273:PMID
2230:PMID
2198:2024
2164:PMID
2133:2012
2094:PMID
2044:2018
2014:2021
1998:PMID
1975:2024
1950:2024
1886:ISBN
1865:2018
1829:ISBN
1802:PMID
1753:PMID
1729:2014
1706:2018
1661:2023
1574:2023
1459:The
1433:and
1398:The
1355:The
1325:oral
1283:and
1275:and
1268:and
1199:and
1177:and
1169:and
1154:and
954:oral
783:and
519:KEGG
499:UNII
488:2162
428:2249
317:Oral
266:data
158:Oral
63:AHFS
3242:C07
3183:PMC
3175:doi
3017:PMC
3007:doi
2959:doi
2913:doi
2755:doi
2718:doi
2675:doi
2671:117
2639:doi
2635:150
2601:doi
2559:doi
2476:doi
2441:doi
2437:279
2404:doi
2363:PMC
2355:doi
2351:174
2308:doi
2304:366
2265:doi
2261:369
2222:doi
2156:doi
2152:120
2084:PMC
2076:doi
1914:hdl
1792:PMC
1784:doi
1743:PMC
1733:doi
1567:FDA
1494:m.
1371:in
1073:or
971:mg
952:mg
584:EPA
448:548
418:CID
204:WHO
6291::
4776:,
4772:,
4768:,
4619:,
4615:,
4611:,
4597:,
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3929:,
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3921:,
3917:,
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