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Biophysical chemistry

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are substances that can accelerate chemical reactions. However, the usage of enzymes in real applications has a lot of limitations, including, but not limited to stability, compatibility, and cost. By using the concept of biophysical chemistry, it is possible to improve those limitations, as well as
168:, the German Nobel Laureate developed it further. In 1971, he improved the research focus by merging two institutes, physical chemistry, and spectroscopy. Nowadays, the research in biophysical chemistry in Göttingen aims to discover life processes using the combined knowledge of science. 362:(DNA) is the molecule that is the basis of all living things. Moreover, it is a main target of anticancer drugs. Studying the interaction between drugs and DNA allows the researcher to develop drugs that could efficiently treat cancer. 335:, or commonly, vitamin B2, has the ability to become a reactive species that can undergo various reactions under the existence of light and oxygen. The significant reaction involved the synthesis of a hydrogel. 258:, also exhibit machine-like dynamics as they act on their substrates. Similarly, the structure and function of the biomembranes may be understood through the study of model supramolecular structures as 128:. The most common feature of the research in this subject is to seek an explanation of the various phenomena in biological systems in terms of either the molecules that make up the system or the 316:
of protein reactions in biological systems. Moreover, it is possible to adjust and engineer biological reactions by applying laser radiation to them. For instance, we can induce the process of
230:. An example of research in biophysical chemistry includes the work for which the 2009 Nobel Prize in Chemistry was awarded. The prize was based on X-ray crystallographic studies of the 339:
is a porous material that can hold a large amount of water while maintaining its shape. The application of hydrogel includes drug delivery, artificial muscles, tissue engineering, etc.
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Biophysical chemists employ various techniques used in physical chemistry to probe the structure of biological systems. These techniques include spectroscopic methods such as
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focused on using NMR to monitor water and protein in biological systems. The study expands the structural understanding of water bonding which explains a lot of phenomena.
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structure of these systems. Apart from the biological applications, recent research showed progress in the medical field as well.
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There are several biological and medical applications that apply the knowledge of biophysical chemistry to benefit humankind.
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molecule or its modification due to binding of a metal ion. The structures of many large protein assemblies, such as
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Introduction to Biophysical Chemistry. Journal of Medical Education: September 1964 - Volume 39 - Issue 9 - p 867
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action can be explained in terms of the shape of a pocket in the protein molecule that matches the shape of the
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that helped to unravel the physical basis of its biological function as a molecular machine that translates
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Biophysical Chemistry - Part II: Techniques for the Study of Biological Structure and Function
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excitations. After the establishment of fundamental biophysical chemistry in Göttingen,
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Current approaches to biophysical research include but are not limited to the study of
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Hmoud Alotaibi, Saad; Abdalla Momen, Awad (2020-02-19), A. A. Khalid, Mohammed (ed.),
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Hmoud Alotaibi, Saad; Abdalla Momen, Awad (2020-02-19), A. A. Khalid, Mohammed (ed.),
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An International Journal devoted to the Physics and Chemistry of Biological Phenomena
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into polypeptides. Other areas in which biophysical chemists engage themselves are
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Biophysical Chemistry - Part I: The Conformation of Biological Macromolecules
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Osbon, Yauheniya; Kumar, Manish (2020-02-19), A. A. Khalid, Mohammed (ed.),
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Biophysical Chemistry - Part III: The Behavior of Biological Macromolecules
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Ionita, Gabriela; Matei, Iulia (2020-02-19), A. A. Khalid, Mohammed (ed.),
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The oldest concept of biophysical chemistry started from the curiosity of
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Modern Biophysical Chemistry: Detection and Analysis of Biomolecules
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Iwata, Koichi; Terazima, Masahide; Masuhara, Hiroshi (2018-02-01).
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Khalid, Mohammed A. A. (2020-02-19). a. a. Khalid, Mohammed (ed.).
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The oldest reputed institute for biophysical chemistry is the
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Biochimica et Biophysica Acta (BBA) - General Subjects
717:"Biophysical Chemistry in Groningen – A Personal Note" 883: 1059:"Biocatalysis and Strategies for Enzyme Improvement" 531:Ball, Vincent; Maechling, Clarisse (28 July 2009). 405:
Biochemical and Biophysical Research Communications
1181: 835:The Nobel Prize in Chemistry 2009 - Press Release 2279: 974: 503: 1228: 1202: 1172: 429:Journal of Biochemical and Biophysical Methods 372:Max Planck Institute for Biophysical Chemistry 1314: 530: 303: 288:is a name to describe the composition of the 1269:: CS1 maint: multiple names: authors list ( 1107:Biophysical Chemistry - Advance Applications 1063:Biophysical Chemistry - Advance Applications 937:Biophysical Chemistry - Advance Applications 849:Biophysical Chemistry - Advance Applications 596:Biophysical Chemistry - Advance Applications 499: 497: 1240:(1st ed.). W.H. Freeman & Co Ltd. 1214:(1st ed.). W.H. Freeman & Co Ltd. 1188:(1st ed.). W.H. Freeman & Co Ltd. 1146:"Foundation & History of the Institute" 930: 537:International Journal of Molecular Sciences 1321: 1307: 1056: 633: 1328: 1114: 1070: 944: 787: 753: 667: 603: 566: 548: 494: 280: 97:Learn how and when to remove this message 714: 312:allow modern scientists to identify the 60:This article includes a list of general 18: 395:Archives of Biochemistry and Biophysics 386:Biophysical chemistry journals include 2280: 1277: 977:"Hydrogel properties and applications" 975:Fu, Jun; in het Panhuis, Marc (2019). 845: 754:Berendsen, Herman J. C. (1962-06-15). 1302: 879: 877: 351:increase the performance of enzymes. 342: 327: 269:of different compositions and sizes. 2236: 1021: 812:"Former Dept. Biophysical Chemistry" 206:, and the detection and analysis of 140: 46: 2260: 354: 13: 1094: 874: 715:Hemminga, Marcus A. (2023-03-16). 583: 66:it lacks sufficient corresponding 14: 2304: 1254: 189: 182:launched a research group at the 2259: 2247: 2235: 2224: 2223: 981:Journal of Materials Chemistry B 634:Bonhoeffer, K. F. (1948-09-20). 504:Peter Jomo Walla (8 July 2014). 242:and the functional structure of 222:(NMR) and other techniques like 51: 1166: 1138: 1050: 1015: 968: 924: 839: 760:The Journal of Chemical Physics 272: 1284:. Royal Society of Chemistry. 828: 804: 747: 708: 684: 627: 524: 171: 1: 1588:Interface and colloid science 1342:Glossary of chemical formulae 640:Journal of General Physiology 487: 411:Biochimica et Biophysica Acta 365: 213: 902:10.1016/j.bbagen.2017.11.003 320:using the technique called " 7: 1865:Bioorganometallic chemistry 1352:List of inorganic compounds 1278:Cooper, Alan (2015-11-09). 465: 460:SociĂ©tĂ© Française de Chimie 381: 10: 2309: 1791:Dynamic covalent chemistry 1762:Enantioselective synthesis 1742:Physical organic chemistry 1695:Organolanthanide chemistry 733:10.1007/s10930-023-10097-6 447:Journal de Chimie Physique 304:Study of Protein Reactions 220:nuclear magnetic resonance 145: 135: 116:that uses the concepts of 2219: 2122: 1883: 1799: 1720: 1670: 1546: 1489: 1380:Electroanalytical methods 1365: 1337: 452:Physico-Chimie Biologique 154:Karl Friedrich Bonhoeffer 2135:Nobel Prize in Chemistry 2051:Supramolecular chemistry 1690:Organometallic chemistry 1116:10.5772/intechopen.85794 1072:10.5772/intechopen.85018 1022:Berg, Jeremy M. (2002). 946:10.5772/intechopen.88855 858:10.5772/intechopen.73426 605:10.5772/intechopen.85794 228:cryo-electron microscopy 178:The renowned scientist, 2073:Combinatorial chemistry 1984:Food physical chemistry 1947:Environmental chemistry 1831:Bioorthogonal chemistry 1757:Retrosynthetic analysis 1578:Chemical thermodynamics 1561:Spectroelectrochemistry 1504:Computational chemistry 434:Journal of Biochemistry 318:protein crystallization 184:University of Groningen 81:more precise citations. 2145:of element discoveries 1991:Agricultural chemistry 1979:Carbohydrate chemistry 1870:Bioinorganic chemistry 1735:Alkane stereochemistry 1680:Coordination chemistry 1509:Mathematical chemistry 1375:Instrumental chemistry 510:. Wiley. pp. 1–. 472:Biophysical techniques 438:Biology and Biophysics 286:Lipid bilayer membrane 281:Study of Cell Membrane 44: 2140:Timeline of chemistry 2037:Post-mortem chemistry 2022:Clandestine chemistry 1952:Atmospheric chemistry 1875:Biophysical chemistry 1707:Solid-state chemistry 1657:Equilibrium chemistry 1566:Photoelectrochemistry 1281:Biophysical Chemistry 420:Biophysical Chemistry 360:Deoxyribonucleic acid 310:spectroscopic methods 110:Biophysical chemistry 22: 2130:History of chemistry 2085:Chemical engineering 1860:Bioorganic chemistry 1610:Structural chemistry 1347:List of biomolecules 550:10.3390/ijms10083283 442:Taylor & Francis 160:on iron to simulate 2153:The central science 2107:Ceramic engineering 2032:Forensic toxicology 2005:Chemistry education 1903:Radiation chemistry 1885:Interdisciplinarity 1838:Medicinal chemistry 1776:Fullerene chemistry 1652:Microwave chemistry 1521:Molecular mechanics 1516:Molecular modelling 772:1962JChPh..36.3297B 721:The Protein Journal 652:10.1085/jgp.32.1.69 389:Biophysical Journal 2196:Chemical substance 2058:Chemical synthesis 2027:Forensic chemistry 1908:Actinide chemistry 1850:Clinical chemistry 1531:Molecular geometry 1526:Molecular dynamics 1481:Elemental analysis 1434:Separation process 1255:Bruce, Martin, R. 1230:Cantor, Charles R. 1204:Cantor, Charles R. 1174:Cantor, Charles R. 993:10.1039/C9TB90023C 816:www.biophys.mpg.de 408:(Academic Press), 343:Enzyme Improvement 328:Hydrogel Synthesis 314:kinetic components 126:biological systems 122:physical chemistry 45: 29:biological machine 2275: 2274: 2211:Quantum mechanics 2176:Chemical compound 2159:Chemical reaction 2097:Materials science 2015:General chemistry 2010:Amateur chemistry 1938:Photogeochemistry 1923:Stellar chemistry 1893:Nuclear chemistry 1814:Molecular biology 1781:Polymer chemistry 1752:Organic synthesis 1747:Organic reactions 1712:Ceramic chemistry 1702:Cluster chemistry 1632:Chemical kinetics 1620:Molecular physics 1499:Quantum chemistry 1412:Mass spectrometry 1291:978-1-78262-510-0 1234:Schimmel, Paul R. 1208:Schimmel, Paul R. 1178:Schimmel, Paul R. 1150:www.mpinat.mpg.de 1126:978-1-78984-047-6 1082:978-1-78984-047-6 987:(10): 1523–1525. 956:978-1-78984-047-6 867:978-1-78984-048-3 780:10.1063/1.1732460 766:(12): 3297–3305. 696:www.mpinat.mpg.de 615:978-1-78984-047-6 517:978-3-527-68354-3 240:protein structure 224:X-ray diffraction 141:Twentieth Century 124:for the study of 107: 106: 99: 43:RNA into proteins 2300: 2263: 2262: 2251: 2239: 2238: 2227: 2226: 2171:Chemical element 1826:Chemical biology 1685:Magnetochemistry 1662:Mechanochemistry 1615:Chemical physics 1556:Electrochemistry 1461:Characterization 1323: 1316: 1309: 1300: 1299: 1295: 1274: 1268: 1260: 1251: 1225: 1199: 1187: 1160: 1159: 1157: 1156: 1142: 1136: 1135: 1134: 1133: 1118: 1098: 1092: 1091: 1090: 1089: 1074: 1054: 1048: 1047: 1019: 1013: 1012: 972: 966: 965: 964: 963: 948: 928: 922: 921: 881: 872: 871: 843: 837: 832: 826: 825: 823: 822: 808: 802: 801: 791: 751: 745: 744: 712: 706: 705: 703: 702: 688: 682: 681: 671: 631: 625: 624: 623: 622: 607: 587: 581: 580: 570: 552: 543:(8): 3283–3315. 528: 522: 521: 501: 416:Elsevier Science 355:Anticancer Drugs 180:Herman Berendsen 158:electric current 114:physical science 102: 95: 91: 88: 82: 77:this article by 68:inline citations 55: 54: 47: 33:protein dynamics 2308: 2307: 2303: 2302: 2301: 2299: 2298: 2297: 2278: 2277: 2276: 2271: 2215: 2118: 2112:Polymer science 2068:Click chemistry 2063:Green chemistry 1957:Ocean chemistry 1933:Biogeochemistry 1879: 1795: 1767:Total synthesis 1730:Stereochemistry 1716: 1666: 1583:Surface science 1573:Thermochemistry 1542: 1485: 1456:Crystallography 1361: 1333: 1327: 1292: 1262: 1261: 1248: 1222: 1196: 1169: 1164: 1163: 1154: 1152: 1144: 1143: 1139: 1131: 1129: 1127: 1099: 1095: 1087: 1085: 1083: 1055: 1051: 1036: 1020: 1016: 973: 969: 961: 959: 957: 929: 925: 882: 875: 868: 844: 840: 833: 829: 820: 818: 810: 809: 805: 752: 748: 713: 709: 700: 698: 692:"Manfred Eigen" 690: 689: 685: 632: 628: 620: 618: 616: 588: 584: 529: 525: 518: 502: 495: 490: 468: 384: 368: 357: 345: 330: 306: 283: 275: 246:. For example, 216: 192: 176: 150: 143: 138: 130:supra-molecular 103: 92: 86: 83: 73:Please help to 72: 56: 52: 17: 12: 11: 5: 2306: 2296: 2295: 2290: 2273: 2272: 2270: 2269: 2257: 2245: 2233: 2220: 2217: 2216: 2214: 2213: 2208: 2203: 2198: 2193: 2188: 2183: 2178: 2173: 2168: 2167: 2166: 2156: 2149: 2148: 2147: 2137: 2132: 2126: 2124: 2120: 2119: 2117: 2116: 2115: 2114: 2109: 2104: 2094: 2093: 2092: 2082: 2081: 2080: 2075: 2070: 2065: 2055: 2054: 2053: 2042: 2041: 2040: 2039: 2034: 2024: 2019: 2018: 2017: 2012: 2001: 2000: 1999: 1998: 1996:Soil chemistry 1988: 1987: 1986: 1981: 1974:Food chemistry 1971: 1969:Carbochemistry 1966: 1964:Clay chemistry 1961: 1960: 1959: 1954: 1943: 1942: 1941: 1940: 1935: 1925: 1919:Astrochemistry 1915:Cosmochemistry 1912: 1911: 1910: 1905: 1900: 1898:Radiochemistry 1889: 1887: 1881: 1880: 1878: 1877: 1872: 1867: 1862: 1857: 1855:Neurochemistry 1852: 1847: 1846: 1845: 1835: 1834: 1833: 1823: 1822: 1821: 1816: 1805: 1803: 1797: 1796: 1794: 1793: 1788: 1786:Petrochemistry 1783: 1778: 1773: 1764: 1759: 1754: 1749: 1744: 1739: 1738: 1737: 1726: 1724: 1718: 1717: 1715: 1714: 1709: 1704: 1699: 1698: 1697: 1687: 1682: 1676: 1674: 1668: 1667: 1665: 1664: 1659: 1654: 1649: 1647:Spin chemistry 1644: 1642:Photochemistry 1639: 1634: 1629: 1627:Femtochemistry 1624: 1623: 1622: 1612: 1607: 1602: 1597: 1596: 1595: 1585: 1580: 1575: 1570: 1569: 1568: 1563: 1552: 1550: 1544: 1543: 1541: 1540: 1539: 1538: 1528: 1523: 1518: 1513: 1512: 1511: 1501: 1495: 1493: 1487: 1486: 1484: 1483: 1478: 1473: 1468: 1463: 1458: 1453: 1452: 1451: 1446: 1439:Chromatography 1436: 1431: 1430: 1429: 1424: 1419: 1409: 1408: 1407: 1402: 1397: 1392: 1382: 1377: 1371: 1369: 1363: 1362: 1360: 1359: 1357:Periodic table 1354: 1349: 1344: 1338: 1335: 1334: 1326: 1325: 1318: 1311: 1303: 1297: 1296: 1290: 1275: 1252: 1246: 1226: 1220: 1200: 1194: 1168: 1165: 1162: 1161: 1137: 1125: 1109:, IntechOpen, 1093: 1081: 1065:, IntechOpen, 1049: 1034: 1014: 967: 955: 939:, IntechOpen, 923: 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2061: 2060: 2059: 2056: 2052: 2049: 2048: 2047: 2046:Nanochemistry 2044: 2043: 2038: 2035: 2033: 2030: 2029: 2028: 2025: 2023: 2020: 2016: 2013: 2011: 2008: 2007: 2006: 2003: 2002: 1997: 1994: 1993: 1992: 1989: 1985: 1982: 1980: 1977: 1976: 1975: 1972: 1970: 1967: 1965: 1962: 1958: 1955: 1953: 1950: 1949: 1948: 1945: 1944: 1939: 1936: 1934: 1931: 1930: 1929: 1926: 1924: 1920: 1916: 1913: 1909: 1906: 1904: 1901: 1899: 1896: 1895: 1894: 1891: 1890: 1888: 1886: 1882: 1876: 1873: 1871: 1868: 1866: 1863: 1861: 1858: 1856: 1853: 1851: 1848: 1844: 1841: 1840: 1839: 1836: 1832: 1829: 1828: 1827: 1824: 1820: 1817: 1815: 1812: 1811: 1810: 1807: 1806: 1804: 1802: 1798: 1792: 1789: 1787: 1784: 1782: 1779: 1777: 1774: 1772: 1771:Semisynthesis 1768: 1765: 1763: 1760: 1758: 1755: 1753: 1750: 1748: 1745: 1743: 1740: 1736: 1733: 1732: 1731: 1728: 1727: 1725: 1723: 1719: 1713: 1710: 1708: 1705: 1703: 1700: 1696: 1693: 1692: 1691: 1688: 1686: 1683: 1681: 1678: 1677: 1675: 1673: 1669: 1663: 1660: 1658: 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Index


ribosome
biological machine
protein dynamics
nanoscales
translate
references
inline citations
improve
introducing
Learn how and when to remove this message
physical science
physics
physical chemistry
biological systems
supra-molecular
Germany
Karl Friedrich Bonhoeffer
electric current
nerve
Manfred Eigen
Netherlands
Herman Berendsen
University of Groningen
ion channels
promoters
stem cells
biomolecules
nuclear magnetic resonance
X-ray diffraction

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