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Charles David Allis

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Hsu, Jer-Yuan; Sun, Zu-Wen; Li, Xiumin; Reuben, Melanie; Tatchell, Kelly; Bishop, Douglas K.; Grushcow, Jeremy M.; Brame, Cynthia J.; Caldwell, Jennifer A.; Hunt, Donald F.; Lin, Rueyling; Smith, M. Mitchell; Allis, C. David (2000).
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Mizzen, Craig A.; Yang, Xiang-Jiao; Kokubo, Tetsuro; Brownell, James E.; Bannister, Andrew J.; Owen-Hughes, Tom; Workman, Jerry; Wang, Lian; Berger, Shelley L.; Kouzarides, Tony; Nakatani, Yoshihiro; Allis, C. David (1996).
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Strahl, Brian D.; Grant, Patrick A.; Briggs, Scott D.; Sun, Zu-Wen; Bone, James R.; Caldwell, Jennifer A.; Mollah, Sahana; Cook, Richard G.; Shabanowitz, Jeffrey; Hunt, Donald F.; Allis, C. David (2002).
1537:"Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation" 4254: 2581: 1150: 4204: 2077:
Nacev, Benjamin A.; Feng, Lijuan; Bagert, John D.; Lemiesz, Agata E.; Gao, JianJiong; Soshnev, Alexey A.; Kundra, Ritika; Schultz, Nikolaus; Muir, Tom W.; Allis, C. David (2019).
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Rice, Judd C.; Briggs, Scott D.; Ueberheide, Beatrix; Barber, Cynthia M.; Shabanowitz, Jeffrey; Hunt, Donald F.; Shinkai, Yoichi; Allis, C. David (2003).
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Hendzel, Michael J.; Wei, Yi; Mancini, Michael A.; Van Hooser, Aaron; Ranalli, Tamara; Brinkley, B. R.; Bazett-Jones, David P.; Allis, C. David (1997).
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stimulation, and established a synergistic relationship between histone phosphorylation and acetylation. He also determined the role of methylation at
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Brownell, James E.; Zhou, Jianxin; Ranalli, Tamara; Kobayashi, Ryuji; Edmondson, Diane G.; Roth, Sharon Y.; Allis, C. David (1996).
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Following this seminal report, Allis continued studying histone acetylation, discovering more histone acetyltransferases, including
4219: 4209: 4224: 2555: 1592:"Mitotic Phosphorylation of Histone H3 Is Governed by Ipl1/aurora Kinase and Glc7/PP1 Phosphatase in Budding Yeast and Nematodes" 733: 2678: 4194: 2375: 278: 2730: 2253: 1899: 3583: 2756: 2503: 2197: 1109: 870: 689: 977: 4229: 3617: 3035: 2525: 955: 274: 1473: 4189: 3228: 2193: 767: 152: 140: 2619: 918: 1633:"Synergistic Coupling of Histone H3 Phosphorylation and Acetylation in Response to Epidermal Growth Factor Stimulation" 1140:"A Tribute to C. David Allis, PhD — Professor in the Department of Biochemistry and Molecular Genetics from 1998-2003" 3736: 2788: 2704: 2257: 4239: 3927: 761: 148: 1277:"Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation" 1324: 845: 411: 3195: 2812: 1722: 841: 333: 17: 1631:
Cheung, Peter; Tanner, Kirk G.; Cheung, Wang L.; Sassone-Corsi, Paolo; Denu, John M.; Allis, C. David (2000).
3720: 2353: 606: 3063: 2999: 2967: 2644: 2320: 2316: 792: 717: 610: 4115: 3696: 3268: 2987: 2413: 1676:"Histone Methyltransferases Direct Different Degrees of Methylation to Define Distinct Chromatin Domains" 798: 164: 2290: 325: 2499: 1718:"Set2 Is a Nucleosomal Histone H3-Selective Methyltransferase That Mediates Transcriptional Repression" 584: 580: 369: 203: 3899: 3611: 2973: 1214: 638: 598: 546: 1373:"Acetylation and methylation of histones and their possible role in the regulation of rna synthesis" 4107: 3444: 2346: 1918: 810: 773: 724: 313: 156: 101: 2911: 1084: 3903: 3879: 3481: 3342: 3217: 3149: 3047: 2648: 2443: 2260: 1250: 1113: 875: 653: 577: 527: 407: 361: 357: 199: 1432:"Pursuing the Secrets of Histone Proteins: An Amazing Journey with a Remarkable Supporting Cast" 542:. Chromatin biology at the time was not a popular topic; nor was the use of ciliated organisms. 473: 414:
Professor of Biology two years later. In 1998, Allis went to the Department of Biochemistry and
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In more recent years, his attention turned to "oncohistones", which are histones with
4135: 4129: 4101: 4014: 3958: 3917: 3857: 3851: 3671: 3430: 3404: 3350: 3298: 3256: 3236: 3085: 3081: 2891: 2840: 2830: 2615: 2582:"2017 March of Dimes Prize awarded to Dr. C. David Allis for groundbreaking research" 2179: 2167: 2140: 2116: 2063: 2051: 2002: 1931: 1904: 1862: 1800: 1751: 1697: 1656: 1613: 1556: 1502: 1453: 1412: 1353: 1300: 1198: 1057: 981: 562: 337: 254: 114: 4121: 3913: 3473: 2383: 1771:"Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast" 1736: 1568: 642: 614: 515: 4004: 3792: 3766: 3700: 3645: 3641: 3549: 3499: 3469: 3400: 3394: 3368: 3294: 3282: 3244: 3185: 3165: 3075: 2957: 2941: 2903: 2858: 2800: 2287:"C. David Allis to Receive the Third Annual Wiley Prize in the Biomedical Sciences" 2264: 2157: 2106: 2098: 2041: 1992: 1984: 1947: 1943: 1923: 1874: 1854: 1812: 1792: 1775: 1741: 1731: 1687: 1646: 1603: 1548: 1492: 1443: 1402: 1392: 1343: 1333: 1290: 1210: 1190: 1047: 1037: 749: 668:, and recognized the clinical significance of histone modifications, especially in 345: 294: 238: 233: 64: 1117: 880: 4157: 4143: 4111: 4066: 4052: 4024: 3893: 3875: 3843: 3806: 3692: 3635: 3621: 3545: 3525: 3511: 3485: 3448: 3360: 3356: 3338: 3324: 3290: 3276: 3272: 3264: 3199: 3179: 3161: 3127: 2983: 2949: 2933: 2796: 1895: 1181: 985: 661: 4008: 2533: 217:
Isolation and characterization of pole cells and polar granules from embryos of
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Allis had been treated for cancer. He died January 8, 2023, at a hospital in
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Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research
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Recipients of the Albert Lasker Award for Basic Medical Research
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The C. David Allis Mentorship Fund for Young Scientists at the
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that distort normal histone modifications, leading to cancers.
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250 Subunit of TFIID Has Histone Acetyltransferase Activity"
1274: 3021: 1534: 591: 332:. The experience attracted him to research, and he went to 298: 68: 2703:. Rockefeller University. January 14, 2023. Archived from 1673: 4205:
Members of the United States National Academy of Sciences
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American Society for Biochemistry and Molecular Biology
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American Society for Biochemistry and Molecular Biology
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transcription). Allis also branched off to researching
2076: 2727:"C. David Allis Mentorship Fund for Young Scientists" 1370: 1240:"2014 Japan Prize Achievement - "Life Science" field" 4200:
Fellows of the American Academy of Arts and Sciences
2289:. Wiley Foundation. January 27, 2004. Archived from 1969:
Chi, Ping; Allis, C. David; Wang, Gang Greg (2010).
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Allfrey, V. G.; Faulkner, R.; Mirsky, A. E. (1964).
253:(March 22, 1951 – January 8, 2023) was an American 1110:"C. David Allis Named Wilson Professor of Biology" 4245:University of Virginia School of Medicine faculty 2612:"2018 Albert Lasker Basic Medical Research Award" 4171: 2778: 1835:"The language of covalent histone modifications" 1320:""Modifying" My Career toward Chromatin Biology" 1172:Goldfarb, David S.; Gorovsky, Martin A. (2009). 1171: 1077:"Former SU professor named Japan Prize Laureate" 410:in 1995, and became the Marie Curran Wilson and 2343:"Past A&S Alumni Award Winners (2002-2019)" 1377:Proceedings of the National Academy of Sciences 1021:Proceedings of the National Academy of Sciences 1588: 786:Albert Lasker Award for Basic Medical Research 664:) explicitly associated the histone code with 648:In 2000, Allis and Brian Strahl proposed the " 161:Albert Lasker Award for Basic Medical Research 3577: 2764: 1894: 780:March of Dimes Prize in Developmental Biology 2701:"Remembering a pioneer of chromatin biology" 1968: 942: 940: 938: 936: 865: 863: 838:"Alum C. David Allis wins 2018 Lasker Award" 344:three years later, under the supervision of 265:. He was also the Head of the Laboratory of 4250:Members of the National Academy of Medicine 1832: 1104: 1102: 336:for graduate studies. He graduated with an 288: 3591: 3584: 3570: 2771: 2757: 2019: 1833:Strahl, Brian D.; Allis, C. David (2000). 42: 3156:The Event Horizon Telescope Collaboration 2254:"Massry Prize Winners ( 1996 – Present )" 2161: 2110: 2045: 1996: 1917: 1745: 1735: 1691: 1650: 1607: 1496: 1447: 1406: 1396: 1347: 1337: 1294: 1051: 1041: 933: 860: 2729:. Rockefeller University. Archived from 1768: 1099: 433:Professor and Head of the Laboratory of 27:American molecular biologist (1951–2023) 1174:"Nuclear Dimorphism: Two Peas in a Pod" 1074: 734:Gairdner Foundation International Award 617:. He linked histone phosphorylation to 14: 4172: 2133: 1013: 1009: 1007: 1005: 1003: 906: 902: 900: 898: 279:Memorial Sloan Kettering Cancer Center 277:(the other two institutions being the 4215:Indiana University Bloomington alumni 3565: 2752: 2198:American Academy of Arts and Sciences 1769:Sun, Zu-Wen; Allis, C. David (2002). 1429: 1317: 690:American Academy of Arts and Sciences 538:that is transcriptionally silent and 392:in 1989. He joined the Department of 844:. September 11, 2018. Archived from 682: 486:Allis was known for his research of 2558:. Gruber Foundation. Archived from 2020:Dent, Sharon; Grewal, Shiv (2023). 1075:Scalese, Sarah (February 4, 2014). 1000: 948:"C. David Allis, Ph.D. (1951-2023)" 895: 768:Breakthrough Prize in Life Sciences 652:hypothesis", which states that DNA 153:Breakthrough Prize in Life Sciences 141:Canada Gairdner International Award 24: 4235:Baylor College of Medicine faculty 2677:. October 13, 2022. Archived from 1149:. January 24, 2023. Archived from 907:Murphy, Brian (January 21, 2023). 879:. January 14, 2023. Archived from 708:Wiley Prize in Biomedical Sciences 565:to Gcn5p, a known transcriptional 25: 4266: 2258:University of Southern California 494:structure. He started working on 320:. He had his first experience of 762:Grand Prix Charles-Leopold Mayer 545:In 1996, his group isolated the 462: 275:Tri-Institutional MD–PhD Program 149:Grand Prix Charles-Leopold Mayer 4220:University of Rochester faculty 4210:University of Cincinnati alumni 4011:/ John Frederick Grassle (2013) 2719: 2693: 2663: 2634: 2604: 2574: 2548: 2518: 2488: 2458: 2428: 2398: 2368: 2335: 2305: 2279: 2246: 2216: 2186: 2127: 2070: 2013: 1962: 1888: 1826: 1762: 1737:10.1128/MCB.22.5.1298-1306.2002 1708: 1667: 1624: 1582: 1528: 1464: 1423: 1364: 1325:Journal of Biological Chemistry 1311: 1268: 1232: 1165: 1116:. July 25, 1997. Archived from 645:regulates histone methylation. 514:is an ideal candidate to study 4225:Rockefeller University faculty 1900:"Translating the histone code" 1723:Molecular and Cellular Biology 1132: 1068: 970: 871:"Charles David Allis ("Dave")" 842:Indiana University Bloomington 830: 820:was established in his honor. 660:. Later, Allis (together with 334:Indiana University Bloomington 13: 1: 4195:American molecular biologists 3721:Ernest John Christopher Polge 2588:. May 8, 2017. Archived from 1693:10.1016/s1097-2765(03)00479-9 1652:10.1016/s1097-2765(00)80256-7 1609:10.1016/S0092-8674(00)00034-9 1498:10.1016/S0092-8674(00)81821-8 1296:10.1016/S0092-8674(00)81063-6 823: 723:Distinguished Alumnus Award, 293:Allis was born and raised in 3064:Sudbury Neutrino Observatory 2645:National Academy of Medicine 2350:College of Arts and Sciences 2317:National Academy of Sciences 2136:"C. David Allis (1951–2023)" 2022:"C. David Allis (1951–2023)" 793:National Academy of Medicine 728:College of Arts and Sciences 718:National Academy of Sciences 401:College of Arts and Sciences 7: 4230:Syracuse University faculty 2988:Supernova Cosmology Project 2224:"2002 Dickson Prize Winner" 2134:Berger, Shelley L. (2023). 1016:"Profile of C. David Allis" 809:when he graduated from the 799:Albany Medical Center Prize 561:, and found the enzyme was 455: 165:Albany Medical Center Prize 10: 4271: 4190:Scientists from Cincinnati 2500:French Academy of Sciences 2047:10.1038/d41586-023-00346-0 1898:; Allis, C. David (2001). 1449:10.1016/j.cell.2018.08.022 370:Baylor College of Medicine 204:Baylor College of Medicine 4090: 3951: 3816: 3737:William Hayward Pickering 3681: 3612:Ephraim Katchalski-Katzir 3600: 3227: 2880: 2787: 2103:10.1038/s41586-019-1038-1 1195:10.1016/j.cub.2009.04.023 840:. Department of Biology, 696:Dickson Prize in Medicine 641:, and found that histone 639:histone methyltransferase 547:histone acetyltransferase 412:Joseph Chamberlain Wilson 368:. In 1981, he joined the 351: 273:, and a professor at the 244: 232: 209: 187: 177: 170: 136: 125: 97: 75: 50: 41: 34: 2530:Breakthrough Prize Board 2347:University of Cincinnati 1430:Allis, C. David (2018). 1318:Allis, C. David (2015). 811:University of Cincinnati 774:Gruber Prize in Genetics 725:University of Cincinnati 656:is largely regulated by 637:-containing proteins as 314:University of Cincinnati 289:Early life and education 157:Gruber Prize in Genetics 102:University of Cincinnati 4240:Massry Prize recipients 3878:/ Keith J. Sainsbury / 3482:Shankar Balasubramanian 3218:Alexander Zamolodchikov 3150:Peter van Nieuwenhuizen 2642:"C. David Allis, Ph.D." 2261:Keck School of Medicine 2163:10.1126/science.adg7738 1928:10.1126/science.1063127 1339:10.1074/jbc.X115.663229 1114:University of Rochester 1043:10.1073/pnas.0602256103 1014:Downey, Philip (2006). 876:The Cincinnati Enquirer 611:histone phosphorylation 429:in 2003 as the Joy and 408:University of Rochester 362:University of Rochester 358:postdoctoral fellowship 221:Drosophila melanogaster 200:University of Rochester 4049:Emmanuelle Charpentier 3668:Frank Sherwood Rowland 3496:Clifford P. Brangwynne 3329:Emmanuelle Charpentier 2675:Albany Medical College 2466:"The 2014 Japan Prize" 1144:University of Virginia 952:Rockefeller University 818:Rockefeller University 805:Allis was a member of 490:and their relation to 427:Rockefeller University 420:University of Virginia 406:Allis returned to the 384:, and was promoted to 283:Weill Cornell Medicine 263:Rockefeller University 196:University of Virginia 192:Rockefeller University 3000:High-Z Supernova Team 1976:Nature Reviews Cancer 1553:10.1007/s004120050256 1398:10.1073/pnas.51.5.786 658:histone modifications 488:histone modifications 376:in the Department of 316:in 1969, majoring in 131:histone modifications 4154:John Michael Wallace 3439:Virginia Man-Yee Lee 3303:Alexander Varshavsky 3122:Jocelyn Bell Burnell 3020:and contributors to 2733:on February 16, 2023 2707:on February 16, 2023 2234:on December 25, 2022 1950:on February 20, 2023 1256:on February 15, 2023 1220:on February 14, 2023 1153:on February 11, 2023 596:transcription factor 475:Charles David Allis 364:after obtaining his 328:(or fourth) year of 4138:/ Kazuo Hagimoto / 3977:Tadamitsu Kishimoto 3707:Jacques-Louis Lions 3423:Jeffrey M. Friedman 3313:Charles David Allis 2998:and members of the 2986:and members of the 2681:on October 14, 2022 2651:on February 8, 2023 2622:on February 8, 2023 2592:on February 8, 2023 2562:on February 1, 2023 2536:on January 16, 2023 2506:on February 7, 2023 2476:on February 2, 2023 2446:on February 6, 2023 2440:Brandeis University 2416:on February 6, 2023 2406:"ASBMB–Merck Award" 2386:on December 6, 2021 2380:Gairdner Foundation 2356:on December 4, 2022 2323:on February 5, 2023 2293:on February 5, 2023 2267:on December 5, 2022 2204:on February 3, 2023 2154:2023Sci...379..645B 2095:2019Natur.567..473N 2038:2023Natur.614..409D 1912:(5532): 1074–1080. 1851:2000Natur.403...41S 1797:10.1038/nature00883 1789:2002Natur.418..104S 1389:1964PNAS...51..786A 1332:(26): 15904–15908. 1120:on October 16, 2019 1087:on October 19, 2021 1081:Syracuse University 1034:2006PNAS..103.6425D 988:on February 7, 2023 958:on January 30, 2023 921:on January 23, 2023 914:The Washington Post 883:on January 17, 2023 848:on February 1, 2023 615:histone methylation 516:histone acetylation 398:Syracuse University 386:associate professor 374:assistant professor 330:Bachelor of Science 301:. His father was a 255:molecular biologist 251:Charles David Allis 36:Charles David Allis 4116:Robert A. Weinberg 4098:Robert G. Gallager 4043:Steven D. Tanksley 4029:Theodore Friedmann 3932:Victor A. McKusick 3890:Masatoshi Takeichi 3838:Timothy R. Parsons 3834:John B. Goodenough 3828:Kimishige Ishizaka 3803:Jack L. Strominger 3799:W. Wesley Peterson 3779:Hiroyuki Yoshikawa 3775:Joseph Engelberger 3751:Edward F. Knipling 3516:Masashi Yanagisawa 3427:Franz-Ulrich Hartl 3357:Stephen J. Elledge 3309:Alim Louis Benabid 3196:Charles H. Bennett 3146:Daniel Z. Freedman 3096:Charles L. Bennett 3060:Arthur B. McDonald 3048:KĹŤichirĹŤ Nishikawa 2978:John Henry Schwarz 2968:Alexander Polyakov 2946:Michel Della Negra 2865:Daniel A. Spielman 2780:Breakthrough Prize 1147:School of Medicine 522:. It has a larger 472:has a profile for 423:School of Medicine 416:Molecular Genetics 380:and Department of 356:Allis undertook a 305:and his mother an 257:, and the Joy and 111:Indiana University 4167: 4166: 4136:Masataka Nakazawa 4130:Christopher Field 4015:Yasuharu Suematsu 3959:Shun-ichi Iwasaki 3918:Peter Shaw Ashton 3858:Benoit Mandelbrot 3852:Andrzej Tarkowski 3672:Elias James Corey 3559: 3558: 3538:Fredrick Van Goor 3431:Arthur L. Horwich 3405:Adrian R. Krainer 3299:Richard P. Lifton 3257:Napoleone Ferrara 3237:Cornelia Bargmann 3086:Andrew Strominger 3082:Joseph Polchinski 2892:Nima Arkani-Hamed 2841:Vincent Lafforgue 2831:Christopher Hacon 2673:(Press release). 2616:Lasker Foundation 2089:(7749): 473–478. 1783:(6893): 104–108. 1516:on April 15, 2019 1189:(11): R449–R452. 1028:(17): 6425–6427. 982:Gruber Foundation 683:Honors and awards 528:transcriptionally 478: 312:. He entered the 307:elementary school 261:Professor at the 248: 247: 172:Scientific career 16:(Redirected from 4262: 4005:C. Grant Willson 3793:Marc Van Montagu 3767:Takashi Sugimura 3701:Xavier Le Pichon 3646:Donald Henderson 3642:Georges Vendryes 3586: 3579: 3572: 3563: 3562: 3550:Andrew Singleton 3500:Anthony A. Hyman 3470:Jeffery W. Kelly 3465: 3457:Richard J. Youle 3401:C. Frank Bennett 3395:Don W. Cleveland 3369:Yoshinori Ohsumi 3295:Robert S. Langer 3283:James P. Allison 3245:Lewis C. Cantley 3186:Hidetoshi Katori 3166:Jens H. Gundlach 3076:Super-Kamiokande 2958:Joseph Incandela 2942:Fabiola Gianotti 2904:Maxim Kontsevich 2859:Takuro Mochizuki 2801:Maxim Kontsevich 2773: 2766: 2759: 2750: 2749: 2743: 2742: 2740: 2738: 2723: 2717: 2716: 2714: 2712: 2697: 2691: 2690: 2688: 2686: 2667: 2661: 2660: 2658: 2656: 2647:. Archived from 2638: 2632: 2631: 2629: 2627: 2618:. Archived from 2608: 2602: 2601: 2599: 2597: 2578: 2572: 2571: 2569: 2567: 2556:"C. David Allis" 2552: 2546: 2545: 2543: 2541: 2532:. Archived from 2526:"C. David Allis" 2522: 2516: 2515: 2513: 2511: 2502:. Archived from 2492: 2486: 2485: 2483: 2481: 2472:. Archived from 2462: 2456: 2455: 2453: 2451: 2442:. Archived from 2432: 2426: 2425: 2423: 2421: 2412:. Archived from 2402: 2396: 2395: 2393: 2391: 2382:. Archived from 2376:"C. David Allis" 2372: 2366: 2365: 2363: 2361: 2352:. Archived from 2339: 2333: 2332: 2330: 2328: 2319:. Archived from 2313:"C. David Allis" 2309: 2303: 2302: 2300: 2298: 2283: 2277: 2276: 2274: 2272: 2263:. Archived from 2250: 2244: 2243: 2241: 2239: 2230:. Archived from 2220: 2214: 2213: 2211: 2209: 2200:. Archived from 2194:"C. David Allis" 2190: 2184: 2183: 2165: 2131: 2125: 2124: 2114: 2074: 2068: 2067: 2049: 2017: 2011: 2010: 2000: 1966: 1960: 1959: 1957: 1955: 1946:. Archived from 1921: 1896:Jenuwein, Thomas 1892: 1886: 1885: 1883: 1881: 1830: 1824: 1823: 1821: 1819: 1766: 1760: 1759: 1749: 1739: 1730:(5): 1298–1306. 1712: 1706: 1705: 1695: 1686:(6): 1591–1598. 1671: 1665: 1664: 1654: 1628: 1622: 1621: 1611: 1586: 1580: 1579: 1577: 1575: 1532: 1526: 1525: 1523: 1521: 1515: 1509:. Archived from 1500: 1491:(7): 1261–1270. 1482: 1468: 1462: 1461: 1451: 1427: 1421: 1420: 1410: 1400: 1368: 1362: 1361: 1351: 1341: 1315: 1309: 1308: 1298: 1272: 1266: 1265: 1263: 1261: 1255: 1249:. Archived from 1244: 1236: 1230: 1229: 1227: 1225: 1219: 1213:. Archived from 1178: 1169: 1163: 1162: 1160: 1158: 1136: 1130: 1129: 1127: 1125: 1106: 1097: 1096: 1094: 1092: 1083:. Archived from 1072: 1066: 1065: 1055: 1045: 1011: 998: 997: 995: 993: 984:. Archived from 978:"C. David Allis" 974: 968: 967: 965: 963: 954:. Archived from 944: 931: 930: 928: 926: 917:. Archived from 904: 893: 892: 890: 888: 867: 858: 857: 855: 853: 834: 557:that acetylates 534:, and a smaller 476: 466: 465: 425:. He joined the 346:Anthony Mahowald 239:Anthony Mahowald 234:Doctoral advisor 228: 82: 60: 58: 46: 32: 31: 21: 4270: 4269: 4265: 4264: 4263: 4261: 4260: 4259: 4170: 4169: 4168: 4163: 4158:Ronald M. Evans 4144:Karl Deisseroth 4140:Gero Miesenböck 4112:Bert Vogelstein 4108:Martin A. Green 4086: 4067:Max Dale Cooper 4053:Jennifer Doudna 4025:Yutaka Takahasi 3947: 3894:Erkki Ruoslahti 3876:Akira Fujishima 3844:Tim Berners-Lee 3812: 3807:Don Craig Wiley 3693:W. Jason Morgan 3677: 3636:Theodore Maiman 3622:Willem J. Kolff 3596: 3590: 3560: 3555: 3546:Ellen Sidransky 3526:Michel Sadelain 3512:Emmanuel Mignot 3486:David Klenerman 3459: 3449:Catherine Dulac 3361:Harry F. Noller 3339:Karl Deisseroth 3325:Jennifer Doudna 3291:Michael N. Hall 3277:Bert Vogelstein 3273:Shinya Yamanaka 3269:Robert Weinberg 3265:Charles Sawyers 3223: 3200:Gilles Brassard 3180:Steven Weinberg 3162:Eric Adelberger 3072:YĹŤichirĹŤ Suzuki 2984:Saul Perlmutter 2950:Tejinder Virdee 2934:Stephen Hawking 2883: 2876: 2797:Simon Donaldson 2783: 2777: 2747: 2746: 2736: 2734: 2725: 2724: 2720: 2710: 2708: 2699: 2698: 2694: 2684: 2682: 2669: 2668: 2664: 2654: 2652: 2640: 2639: 2635: 2625: 2623: 2610: 2609: 2605: 2595: 2593: 2580: 2579: 2575: 2565: 2563: 2554: 2553: 2549: 2539: 2537: 2524: 2523: 2519: 2509: 2507: 2494: 2493: 2489: 2479: 2477: 2464: 2463: 2459: 2449: 2447: 2434: 2433: 2429: 2419: 2417: 2404: 2403: 2399: 2389: 2387: 2374: 2373: 2369: 2359: 2357: 2341: 2340: 2336: 2326: 2324: 2311: 2310: 2306: 2296: 2294: 2285: 2284: 2280: 2270: 2268: 2252: 2251: 2247: 2237: 2235: 2222: 2221: 2217: 2207: 2205: 2192: 2191: 2187: 2132: 2128: 2075: 2071: 2018: 2014: 1989:10.1038/nrc2876 1967: 1963: 1953: 1951: 1893: 1889: 1879: 1877: 1845:(6765): 41–45. 1831: 1827: 1817: 1815: 1767: 1763: 1713: 1709: 1672: 1668: 1629: 1625: 1587: 1583: 1573: 1571: 1533: 1529: 1519: 1517: 1513: 1480: 1477: 1469: 1465: 1428: 1424: 1369: 1365: 1316: 1312: 1273: 1269: 1259: 1257: 1253: 1242: 1238: 1237: 1233: 1223: 1221: 1217: 1182:Current Biology 1176: 1170: 1166: 1156: 1154: 1138: 1137: 1133: 1123: 1121: 1108: 1107: 1100: 1090: 1088: 1073: 1069: 1012: 1001: 991: 989: 976: 975: 971: 961: 959: 946: 945: 934: 924: 922: 905: 896: 886: 884: 869: 868: 861: 851: 849: 836: 835: 831: 826: 685: 662:Thomas Jenuwein 602: 587:transcription. 484: 483: 482: 467: 463: 458: 354: 291: 226: 202: 198: 194: 163: 159: 155: 151: 147: 143: 109: 93: 84: 80: 79:January 8, 2023 71: 62: 56: 54: 37: 28: 23: 22: 15: 12: 11: 5: 4268: 4258: 4257: 4252: 4247: 4242: 4237: 4232: 4227: 4222: 4217: 4212: 4207: 4202: 4197: 4192: 4187: 4182: 4165: 4164: 4162: 4161: 4147: 4133: 4122:Katalin KarikĂł 4119: 4105: 4094: 4092: 4088: 4087: 4085: 4084: 4077:Yoshio Okamoto 4074: 4071:Jacques Miller 4060: 4046: 4036: 4022: 4019:C. David Allis 4012: 4002: 3995:Nicholas Lydon 3984: 3973:Dennis Ritchie 3966: 3963:Peter Vitousek 3955: 3953: 3949: 3948: 3946: 3945: 3938:Dennis Meadows 3935: 3928:Robert E. Kahn 3921: 3914:Peter GrĂĽnberg 3907: 3897: 3883: 3880:John H. Lawton 3869: 3862:James A. Yorke 3855: 3841: 3831: 3820: 3818: 3814: 3813: 3811: 3810: 3796: 3782: 3764: 3757:Charles K. Kao 3754: 3744: 3741:Arvid Carlsson 3734: 3731:Kary B. Mullis 3724: 3714: 3704: 3685: 3683: 3679: 3678: 3676: 3675: 3665: 3658:Luc Montagnier 3639: 3628:Henry Beachell 3625: 3618:David Turnbull 3615: 3608:John R. Pierce 3604: 3602: 3598: 3597: 3589: 3588: 3581: 3574: 3566: 3557: 3556: 3554: 3553: 3534:Paul Negulescu 3519: 3504:Demis Hassabis 3493: 3474:Katalin KarikĂł 3467: 3442: 3420: 3413:Xiaowei Zhuang 3398: 3387:Kazutoshi Mori 3376: 3354: 3332: 3306: 3280: 3253:Titia de Lange 3241:David Botstein 3233: 3231: 3225: 3224: 3222: 3221: 3211: 3193: 3183: 3173: 3159: 3153: 3142:Sergio Ferrara 3135: 3125: 3115: 3108:Lyman Page Jr. 3104:Norman Jarosik 3093: 3079: 3068:Takaaki Kajita 3025: 3024:project (2016) 3003: 2981: 2971: 2965: 2927: 2916:Nathan Seiberg 2912:Juan Maldacena 2888: 2886: 2878: 2877: 2875: 2874: 2868: 2862: 2856: 2850: 2844: 2838: 2835:James McKernan 2828: 2822: 2816: 2813:Richard Taylor 2793: 2791: 2785: 2784: 2776: 2775: 2768: 2761: 2753: 2745: 2744: 2718: 2692: 2662: 2633: 2603: 2586:March of Dimes 2573: 2547: 2517: 2487: 2457: 2436:"Past Winners" 2427: 2397: 2367: 2334: 2304: 2278: 2245: 2215: 2185: 2126: 2069: 2012: 1983:(7): 457–469. 1961: 1919:10.1.1.453.900 1887: 1825: 1761: 1707: 1680:Molecular Cell 1666: 1645:(6): 905–915. 1638:Molecular Cell 1623: 1602:(3): 279–291. 1581: 1547:(6): 348–360. 1527: 1475: 1463: 1422: 1383:(5): 786–794. 1363: 1310: 1289:(6): 843–851. 1267: 1231: 1164: 1131: 1098: 1067: 999: 969: 932: 894: 859: 828: 827: 825: 822: 807:Phi Beta Kappa 803: 802: 796: 791:Member of the 789: 783: 777: 771: 765: 759: 753: 747: 737: 731: 721: 711: 705: 699: 693: 688:Member of the 684: 681: 643:ubiquitylation 600: 468: 461: 460: 459: 457: 454: 390:full professor 353: 350: 340:in 1975 and a 322:basic research 290: 287: 246: 245: 242: 241: 236: 230: 229: 213: 207: 206: 189: 185: 184: 179: 175: 174: 168: 167: 138: 134: 133: 127: 126:Known for 123: 122: 99: 95: 94: 85: 83:(aged 71) 77: 73: 72: 63: 61:March 22, 1951 52: 48: 47: 39: 38: 35: 26: 18:C. David Allis 9: 6: 4: 3: 2: 4267: 4256: 4253: 4251: 4248: 4246: 4243: 4241: 4238: 4236: 4233: 4231: 4228: 4226: 4223: 4221: 4218: 4216: 4213: 4211: 4208: 4206: 4203: 4201: 4198: 4196: 4193: 4191: 4188: 4186: 4183: 4181: 4178: 4177: 4175: 4159: 4155: 4151: 4150:Brian Hoskins 4148: 4145: 4141: 4137: 4134: 4131: 4127: 4126:Drew Weissman 4123: 4120: 4117: 4113: 4109: 4106: 4103: 4099: 4096: 4095: 4093: 4089: 4082: 4078: 4075: 4072: 4068: 4064: 4063:Akira Yoshino 4061: 4058: 4054: 4050: 4047: 4044: 4040: 4037: 4034: 4033:Alain Fischer 4030: 4026: 4023: 4020: 4016: 4013: 4010: 4006: 4003: 4000: 3999:Masato Sagawa 3996: 3992: 3988: 3985: 3982: 3981:Toshio Hirano 3978: 3974: 3970: 3967: 3964: 3960: 3957: 3956: 3954: 3950: 3943: 3942:David E. Kuhl 3939: 3936: 3933: 3929: 3925: 3922: 3919: 3915: 3911: 3908: 3905: 3901: 3900:John Houghton 3898: 3895: 3891: 3887: 3884: 3881: 3877: 3873: 3872:Kenichi Honda 3870: 3867: 3863: 3859: 3856: 3853: 3849: 3845: 3842: 3839: 3835: 3832: 3829: 3825: 3822: 3821: 3819: 3815: 3808: 3804: 3800: 3797: 3794: 3790: 3786: 3783: 3780: 3776: 3772: 3768: 3765: 3762: 3758: 3755: 3752: 3748: 3747:Nick Holonyak 3745: 3742: 3738: 3735: 3732: 3728: 3725: 3722: 3718: 3715: 3712: 3708: 3705: 3702: 3698: 3694: 3690: 3689:Marvin Minsky 3687: 3686: 3684: 3680: 3673: 3669: 3666: 3663: 3659: 3655: 3651: 3647: 3643: 3640: 3637: 3633: 3629: 3626: 3623: 3619: 3616: 3613: 3609: 3606: 3605: 3603: 3599: 3594: 3587: 3582: 3580: 3575: 3573: 3568: 3567: 3564: 3551: 3547: 3543: 3542:Thomas Gasser 3539: 3535: 3531: 3530:Sabine Hadida 3527: 3523: 3520: 3517: 3513: 3509: 3505: 3501: 3497: 3494: 3491: 3487: 3483: 3479: 3478:Drew Weissman 3475: 3471: 3468: 3463: 3458: 3454: 3450: 3446: 3443: 3440: 3436: 3432: 3428: 3424: 3421: 3418: 3414: 3410: 3409:Angelika Amon 3406: 3402: 3399: 3396: 3392: 3388: 3384: 3380: 3377: 3374: 3370: 3366: 3365:Roeland Nusse 3362: 3358: 3355: 3352: 3348: 3344: 3340: 3336: 3335:Edward Boyden 3333: 3330: 3326: 3322: 3318: 3317:Victor Ambros 3314: 3310: 3307: 3304: 3300: 3296: 3292: 3288: 3287:Mahlon DeLong 3284: 3281: 3278: 3274: 3270: 3266: 3262: 3258: 3254: 3250: 3246: 3242: 3238: 3235: 3234: 3232: 3230: 3229:Life sciences 3226: 3219: 3215: 3212: 3209: 3208:Peter W. Shor 3205: 3204:David Deutsch 3201: 3197: 3194: 3191: 3187: 3184: 3181: 3177: 3174: 3171: 3170:Blayne Heckel 3167: 3163: 3160: 3157: 3154: 3151: 3147: 3143: 3139: 3136: 3133: 3129: 3126: 3123: 3119: 3116: 3113: 3112:David Spergel 3109: 3105: 3101: 3097: 3094: 3091: 3087: 3083: 3080: 3077: 3073: 3069: 3065: 3061: 3057: 3053: 3049: 3045: 3041: 3040:Atsuto Suzuki 3037: 3036:Daya Bay team 3033: 3029: 3026: 3023: 3019: 3015: 3011: 3010:Ronald Drever 3007: 3004: 3001: 2997: 2993: 2992:Brian Schmidt 2989: 2985: 2982: 2979: 2975: 2974:Michael Green 2972: 2969: 2966: 2963: 2959: 2955: 2954:Guido Tonelli 2951: 2947: 2943: 2939: 2935: 2931: 2928: 2925: 2924:Edward Witten 2921: 2917: 2913: 2909: 2905: 2901: 2900:Alexei Kitaev 2897: 2893: 2890: 2889: 2887: 2885: 2879: 2872: 2871:Simon Brendle 2869: 2866: 2863: 2860: 2857: 2854: 2853:Martin Hairer 2851: 2848: 2845: 2842: 2839: 2836: 2832: 2829: 2826: 2825:Jean Bourgain 2823: 2820: 2817: 2814: 2810: 2806: 2802: 2798: 2795: 2794: 2792: 2790: 2786: 2781: 2774: 2769: 2767: 2762: 2760: 2755: 2754: 2751: 2732: 2728: 2722: 2706: 2702: 2696: 2680: 2676: 2672: 2666: 2650: 2646: 2643: 2637: 2621: 2617: 2613: 2607: 2591: 2587: 2583: 2577: 2561: 2557: 2551: 2535: 2531: 2527: 2521: 2505: 2501: 2498:(in French). 2497: 2491: 2475: 2471: 2467: 2461: 2445: 2441: 2437: 2431: 2415: 2411: 2407: 2401: 2385: 2381: 2377: 2371: 2355: 2351: 2348: 2344: 2338: 2322: 2318: 2314: 2308: 2292: 2288: 2282: 2266: 2262: 2259: 2255: 2249: 2233: 2229: 2228:Dickson Prize 2225: 2219: 2203: 2199: 2195: 2189: 2181: 2177: 2173: 2169: 2164: 2159: 2155: 2151: 2148:(6633): 645. 2147: 2143: 2142: 2137: 2130: 2122: 2118: 2113: 2108: 2104: 2100: 2096: 2092: 2088: 2084: 2080: 2073: 2065: 2061: 2057: 2053: 2048: 2043: 2039: 2035: 2032:(7948): 409. 2031: 2027: 2023: 2016: 2008: 2004: 1999: 1994: 1990: 1986: 1982: 1978: 1977: 1972: 1965: 1949: 1945: 1941: 1937: 1933: 1929: 1925: 1920: 1915: 1911: 1907: 1906: 1901: 1897: 1891: 1876: 1872: 1868: 1864: 1860: 1859:10.1038/47412 1856: 1852: 1848: 1844: 1840: 1836: 1829: 1814: 1810: 1806: 1802: 1798: 1794: 1790: 1786: 1782: 1778: 1777: 1772: 1765: 1757: 1753: 1748: 1743: 1738: 1733: 1729: 1725: 1724: 1719: 1711: 1703: 1699: 1694: 1689: 1685: 1681: 1677: 1670: 1662: 1658: 1653: 1648: 1644: 1640: 1639: 1634: 1627: 1619: 1615: 1610: 1605: 1601: 1597: 1593: 1585: 1570: 1566: 1562: 1558: 1554: 1550: 1546: 1542: 1538: 1531: 1512: 1508: 1504: 1499: 1494: 1490: 1486: 1479: 1467: 1459: 1455: 1450: 1445: 1441: 1437: 1433: 1426: 1418: 1414: 1409: 1404: 1399: 1394: 1390: 1386: 1382: 1378: 1374: 1367: 1359: 1355: 1350: 1345: 1340: 1335: 1331: 1327: 1326: 1321: 1314: 1306: 1302: 1297: 1292: 1288: 1284: 1283: 1278: 1271: 1252: 1248: 1241: 1235: 1216: 1212: 1208: 1204: 1200: 1196: 1192: 1188: 1184: 1183: 1175: 1168: 1152: 1148: 1145: 1141: 1135: 1119: 1115: 1111: 1105: 1103: 1086: 1082: 1078: 1071: 1063: 1059: 1054: 1049: 1044: 1039: 1035: 1031: 1027: 1023: 1022: 1017: 1010: 1008: 1006: 1004: 987: 983: 979: 973: 957: 953: 949: 943: 941: 939: 937: 920: 916: 915: 910: 903: 901: 899: 882: 878: 877: 872: 866: 864: 847: 843: 839: 833: 829: 821: 819: 814: 812: 808: 800: 797: 794: 790: 787: 784: 781: 778: 775: 772: 769: 766: 763: 760: 757: 754: 751: 748: 745: 741: 738: 735: 732: 729: 726: 722: 719: 715: 712: 709: 706: 703: 700: 697: 694: 691: 687: 686: 680: 678: 673: 671: 667: 663: 659: 655: 654:transcription 651: 646: 644: 640: 636: 633:, identified 632: 628: 624: 620: 616: 612: 608: 604: 597: 594:(part of the 593: 588: 586: 582: 579: 578:transcription 576: 572: 568: 564: 560: 556: 552: 548: 543: 541: 537: 533: 529: 525: 521: 517: 513: 509: 506: 503: 499: 498: 493: 489: 480: 479: 471: 453: 451: 447: 442: 440: 436: 432: 428: 424: 421: 417: 413: 409: 404: 402: 399: 395: 391: 387: 383: 379: 375: 371: 367: 363: 359: 349: 347: 343: 339: 335: 331: 327: 323: 319: 315: 311: 308: 304: 300: 296: 286: 284: 280: 276: 272: 268: 264: 260: 256: 252: 243: 240: 237: 235: 231: 224: 223: 219: 218: 214: 212: 208: 205: 201: 197: 193: 190: 186: 183: 180: 176: 173: 169: 166: 162: 158: 154: 150: 146: 142: 139: 135: 132: 128: 124: 120: 116: 112: 107: 103: 100: 96: 92: 88: 78: 74: 70: 66: 53: 49: 45: 40: 33: 30: 19: 4102:Svante Pääbo 4039:Hideo Hosono 4018: 4009:Jean FrĂ©chet 3991:Brian Druker 3987:Janet Rowley 3969:Ken Thompson 3886:Makoto Nagao 3848:Anne McLaren 3789:Jozef Schell 3717:Gerhard Ertl 3711:John J. Wild 3697:Dan McKenzie 3662:Robert Gallo 3654:Frank Fenner 3632:Gurdev Khush 3490:Pascal Mayer 3435:David Julius 3417:Zhijian Chen 3383:Peter Walter 3379:Joanne Chory 3351:Svante Pääbo 3312: 3249:Hans Clevers 3175: 3137: 3128:Charles Kane 3117: 3100:Gary Hinshaw 3018:Rainer Weiss 3005: 2964:(LHC) (2013) 2929: 2908:Andrei Linde 2737:February 16, 2735:. Retrieved 2731:the original 2721: 2711:February 16, 2709:. Retrieved 2705:the original 2695: 2683:. Retrieved 2679:the original 2665: 2653:. Retrieved 2649:the original 2636: 2624:. Retrieved 2620:the original 2606: 2594:. Retrieved 2590:the original 2576: 2564:. Retrieved 2560:the original 2550: 2538:. Retrieved 2534:the original 2520: 2508:. Retrieved 2504:the original 2490: 2478:. Retrieved 2474:the original 2460: 2448:. Retrieved 2444:the original 2430: 2418:. Retrieved 2414:the original 2400: 2388:. Retrieved 2384:the original 2370: 2358:. Retrieved 2354:the original 2337: 2325:. Retrieved 2321:the original 2307: 2295:. 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Retrieved 846:the original 832: 815: 804: 746:Award (2008) 702:Massry Prize 674: 650:histone code 647: 589: 567:co-activator 550: 544: 536:micronucleus 524:macronucleus 520:dual nucleus 511: 495: 485: 474: 443: 437:Biology and 431:Jack Fishman 405: 388:in 1986 and 382:Cell Biology 378:Biochemistry 355: 303:city planner 292: 269:Biology and 259:Jack Fishman 250: 249: 222: 215: 188:Institutions 171: 129:Research of 81:(2023-01-08) 29: 4185:2023 deaths 4180:1951 births 3910:Albert Fert 3866:Seiji Ogawa 3727:Frank Press 3593:Japan Prize 3508:John Jumper 3460: [ 3445:David Baker 3391:Kim Nasmyth 3373:Huda Zoghbi 3347:Helen Hobbs 3321:Gary Ruvkun 3261:Eric Lander 3132:Eugene Mele 3090:Cumrun Vafa 3078:team (2016) 3032:Kam-Biu Luk 3028:Yifang Wang 2938:Peter Jenni 2882:Fundamental 2809:Terence Tao 2805:Jacob Lurie 2789:Mathematics 2685:October 14, 2655:February 8, 2626:February 8, 2596:February 8, 2566:February 1, 2540:January 16, 2510:February 7, 2480:February 6, 2470:Japan Prize 2450:February 6, 2420:February 6, 2390:February 6, 2360:February 6, 2327:February 5, 2297:February 5, 2271:December 5, 2238:February 3, 2208:February 3, 1247:Japan Prize 1124:October 16, 1091:October 19, 992:February 7, 962:January 30, 925:January 23, 887:January 30, 852:February 1, 756:Japan Prize 666:epigenetics 551:Tetrahymena 530:active and 518:due to its 512:Tetrahymena 505:unicellular 497:Tetrahymena 439:Epigenetics 271:Epigenetics 182:Epigenetics 145:Japan Prize 4174:Categories 4081:Rattan Lal 4057:Adi Shamir 3904:Akira Endo 3824:Ian McHarg 3771:Bruce Ames 3650:Isao Arita 3595:recipients 3343:John Hardy 3214:John Cardy 3014:Kip Thorne 2996:Adam Riess 2960:(CMS) and 2920:Ashoke Sen 2847:Alex Eskin 1541:Chromosoma 824:References 635:SET domain 631:histone H3 605:needed to 581:activation 563:homologous 477:(Q1064064) 450:Washington 295:Cincinnati 91:Washington 65:Cincinnati 57:1951-03-22 3924:Vint Cerf 3785:Leo Esaki 3761:Masao Ito 3522:Carl June 3453:Dennis Lo 2962:Lyn Evans 2944:(ATLAS), 2896:Alan Guth 2782:laureates 2180:256901502 2064:256577181 1914:CiteSeerX 677:mutations 585:regulates 549:p55 from 508:eukaryote 492:chromatin 435:Chromatin 403:in 1990. 267:Chromatin 98:Education 3074:and the 3062:and the 3050:and the 3042:and the 3034:and the 2819:Ian Agol 2172:36795814 2121:30894748 2056:36737544 2007:20574448 1936:11498575 1867:10638745 1805:12077605 1756:11839797 1702:14690610 1661:10911985 1618:10975519 1569:29723188 1474:"The TAF 1458:30217363 1417:14172992 1358:25944906 1203:19515351 1062:16618930 607:initiate 559:histones 540:germline 526:that is 502:ciliated 456:Research 3176:Special 3138:Special 3118:Special 3044:KamLAND 3006:Special 2930:Special 2884:physics 2150:Bibcode 2141:Science 2112:6512987 2091:Bibcode 2034:Bibcode 1998:3262678 1944:1883924 1905:Science 1875:4418993 1847:Bibcode 1813:4338471 1785:Bibcode 1561:9362543 1507:8980232 1385:Bibcode 1349:4481195 1305:8601308 1211:9841779 1053:1458902 1030:Bibcode 716:of the 670:cancers 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Index

C. David Allis

Cincinnati
Ohio
Seattle
Washington
University of Cincinnati
BSc
Indiana University
MSc
PhD
histone modifications
Canada Gairdner International Award
Japan Prize
Grand Prix Charles-Leopold Mayer
Breakthrough Prize in Life Sciences
Gruber Prize in Genetics
Albert Lasker Award for Basic Medical Research
Albany Medical Center Prize
Epigenetics
Rockefeller University
University of Virginia
University of Rochester
Baylor College of Medicine
Thesis
Isolation and characterization of pole cells and polar granules from embryos of
Drosophila melanogaster
Doctoral advisor
Anthony Mahowald
molecular biologist

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