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235:. Caskey then became senior investigator, Laboratory of Biochemical Genetics (1967β70) and head, Section of Medical Genetics at NHLI (1970β71). He is credited with discovery of the universality of the genetic code and its start and stop punctuation mechanisms (NIH, Health Molecular Biology Award). As an Advisor to National Aeronautics and Space Administration (NASA)'s Mars Mission, Caskey was involved in exploring this "universality" in a broader space context.
191:
and now over 40 additional diseases (Giovanni
Herenzini Foundation Prize). One of his more widely used discoveries was that of a simple PCR test for DNA evidence at crime scenes that is now standard practice among police services in the western world. (Courage in DNA Award, DOJ). It was first validated to clarify Gulf War casualties.
301:
and
Facultad de Medicina y Hospital Universitario de la Universidad Autonoma de Nuevo LeΓ³n and continues to serve as a member of the Scientific Commission to Prevent Epidemic and Emergency Health Issues in Nuevo LeΓ³n. For his service to biotechnology development in Mexico be received the Governor of
348:
In the United States, Caskey has served on advisory boards and review panels for the
National Institutes of Health and the Food & Drug Administration, and internationally as a special advisor to the World Health Organization (WHO) Hereditary Diseases Program, and as a member of the WHO's Expert
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Over a period of more than 30 years, Caskey has served as a member or chair of the scientific advisory boards of more than a dozen bio-medical corporations, largely focused on human genetics and related gene therapies for muscular dystrophy and other neuro-muscular diseases. He was a Fellow of the
190:
Caskey's research over a period of more than 50 years has focused on the genetic basis of human diseases and their molecular diagnosis. He discovered the molecular basis of disease "anticipation" as an expansion of short tandem repeat DNA sequences causative of
FragileX, Myotonic Dystrophy, Ataxia,
246:, where he served as Chairman for the next two decades. At Baylor he served as Chief, Section of Medical Genetics (1971β85) and Professor of Medicine and Biochemistry (1971β94). From 1976 to 1994 Caskey was an Investigator at the
178:
305:
In recent years, his work has also involved cooperation with biomedical researchers in the
Taizhou Cardiovascular R&D Centre and the Guangshou Institute of Biomedicine and Health (GIBH),
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of Cogene
Biotech Ventures and Cogene Ventures, venture capital funds designed to support early-stage biotechnology and life sciences companies using genome technology for drug discovery.
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and was first to establish the undiagnosed disease program of children. For his service to genomics research in Canada he was made a Fellow of the
Academy of Science of the
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Nuevo LeΓ³n Award for
Cooperation in Education and Investigation (2009) and the "Flame of Truth" award for backing up biotechnology's development in Mexico (2014).
359:
In 2006, Caskey was appointed director and CEO-elect of the Brown
Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, part of the
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Caskey has had a long engagement with medical science in other countries, notably Canada, Mexico and China. From 2002 to 2009 he was a member of the Board of
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In 1994 Caskey left academia to become senior vice president for research at Merck
Pharmaceuticals and Vaccines. He was trustee and president of The
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686:
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711:
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370:, a medical technology company based in San Diego, using artificial intelligence to prevent diseases associated with aging.
215:. Caskey received his M.D. degree in 1963 and completed internship and residency in the Department of Medicine (1963β65).
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261:. He has trained 67 Post-Doctoral Fellows and 25 Doctoral graduates. He has published 480 academic papers.
227:(NIH) (1965 -1971) where he was a research associate at the National Heart and Lung Institute (NHLI) with
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and biomedical researcher and entrepreneur. He was a Professor of Molecular and Human Genetics at
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at Baylor. While on sabbatical leave from Baylor in 1979β80, Caskey was a Faculty Scholar at the
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Research Institute at the Merck Research Laboratories in Sumneytown Pike, West Point,
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In 1971, Caskey left NIH to found the Department of Molecular and Human Genetics at
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EDITOR OF THE ANNUAL REVIEW OF MEDICINE - VOLUME 70, 2019 : C. Thomas Caskey
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and from 2009 to 2012 he served as Chair of that organization. During his tenure,
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C. Thomas Caskey Will Direct Brown Foundation Institute of Molecular Medicine
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Medical School (1958β63). He was a student biochemical fellow (1961β62) with
445:"Annual Review of Medicine, Planning Editorial Committee - Volume 70, 2019"
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Casked served as director of the Joint Postdoctoral Program between the
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158:
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598:"Dr.C.THOMAS Caskey - Baylor College of Medicine - Allied Academies"
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In 2019, Caskey took up a new role as Chief Medical Officer of
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from 2001 to 2019. He was a member of the editorial boards of
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In 2000, Caskey returned to Houston as founding director and
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Members of the United States National Academy of Sciences
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622:"World Expert in Genetics Joins Human Longevity as CMO"
149:(September 12, 1938 β January 13, 2022), also known as
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Baylor College of Medicine physicians and researchers
363:, where he created the Texas Therapeutics Institute.
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Academy of Medicine, Engineering and Science of Texas
211:, a pioneer in the study of the biochemical basis of
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University of Texas Health Science Center at Houston
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University of Texas Health Science Center at Houston
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and numerous other medical and scientific journals.
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American Association for the Advancement of Science
333:. From 1990 to 1991 he served as president of the
663:
717:Fellows of the American Academy of Microbiology
179:Proceedings of the National Academy of Sciences
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341:(1988-1990) and in 2004β05, President of the
727:Members of the National Academy of Medicine
658:, announcement by UT Health Science Center
574:"EW Healthcare Partners Team - Tom Caskey"
514:"Profile - Weill Cornell Medicine - Qatar"
702:Duke University School of Medicine alumni
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386:
482:"C Thomas Caskey, MD, FACP, FACMG, FRSC"
185:, the Encyclopedia of Molecular Medicine
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732:People from Lancaster, South Carolina
687:American health care chief executives
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257:unit with another Nobel Prize-winner
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323:American College of Medical Genetics
712:Howard Hughes Medical Investigators
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722:Annual Reviews (publisher) editors
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349:Advisory Panel on Human Genetics.
335:American Society of Human Genetics
138:American Society of Human Genetics
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315:American Society of Microbiology
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248:Howard Hughes Medical Institute
16:American geneticist (1938β2022)
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389:"C. Thomas Caskey (1938β2022)"
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327:American College of Physicians
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387:Witkowski, Jan (2022-03-11).
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225:National Institutes of Health
201:University of South Carolina
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67:University of South Carolina
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307:Chinese Academy of Sciences
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647:Curriculum Vitae of Caskey
641:External links and sources
414:10.1038/d41586-022-00714-2
240:Baylor College of Medicine
163:Baylor College of Medicine
109:Baylor College of Medicine
339:Human Genome Organization
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172:Annual Review of Medicine
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43:Lancaster, South Carolina
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255:Medical Research Council
134:2021 William Allan Award
518:qatar-weill.cornell.edu
331:Royal Society of Canada
292:Royal Society of Canada
157:who has been a medical
626:www.humanlongevity.com
147:Charles Thomas Caskey
697:American geneticists
692:American biochemists
578:www.ewhealthcare.com
252:Cambridge University
199:Caskey attended the
602:alliedacademies.com
405:2022Natur.603..386W
337:, President of the
209:James B. Wyngaarden
100:Biomedical genetics
81:William Allan Award
649:on the website of
233:Marshall Nirenberg
223:Caskey trained at
153:, was an American
39:September 12, 1938
551:www.bloomberg.com
547:"C Thomas Caskey"
213:metabolic disease
165:, and served as
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91:Scientific career
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628:. Archived from
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54:January 13, 2022
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23:C. Thomas Caskey
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368:Human Longevity
286:discovered the
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205:Duke University
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123:External videos
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71:Duke University
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63:Alma mater
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632:on 2020-07-22.
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449:Annual Reviews
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259:Sydney Brenner
244:Houston, Texas
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630:the original
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521:. Retrieved
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454:29 September
452:. Retrieved
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105:Institutions
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56:(2022-01-13)
677:2022 deaths
672:1938 births
486:www.bcm.edu
229:Nobel Prize
666:Categories
651:Identigene
607:2021-05-25
583:2021-05-25
556:2021-05-25
523:2021-05-25
491:9 December
374:References
288:SARS Virus
159:Geneticist
35:1938-09-12
431:247407254
294:in 2010.
195:Education
155:internist
423:35277690
329:and the
231:-winner
401:Bibcode
183:Science
169:of the
140:, 2021.
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393:Nature
321:, the
317:, the
269:Genome
219:Career
167:editor
97:Fields
84:(2021)
77:Awards
45:, U.S.
427:S2CID
266:Merck
493:2019
456:2021
419:PMID
325:the
177:the
51:Died
29:Born
409:doi
397:603
354:CEO
242:in
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