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C. Thomas Caskey

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130: 235:. Caskey then became senior investigator, Laboratory of Biochemical Genetics (1967–70) and head, Section of Medical Genetics at NHLI (1970–71). He is credited with discovery of the universality of the genetic code and its start and stop punctuation mechanisms (NIH, Health Molecular Biology Award). As an Advisor to National Aeronautics and Space Administration (NASA)'s Mars Mission, Caskey was involved in exploring this "universality" in a broader space context. 191:
and now over 40 additional diseases (Giovanni Herenzini Foundation Prize). One of his more widely used discoveries was that of a simple PCR test for DNA evidence at crime scenes that is now standard practice among police services in the western world. (Courage in DNA Award, DOJ). It was first validated to clarify Gulf War casualties.
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and Facultad de Medicina y Hospital Universitario de la Universidad Autonoma de Nuevo LeΓ³n and continues to serve as a member of the Scientific Commission to Prevent Epidemic and Emergency Health Issues in Nuevo LeΓ³n. For his service to biotechnology development in Mexico be received the Governor of
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In the United States, Caskey has served on advisory boards and review panels for the National Institutes of Health and the Food & Drug Administration, and internationally as a special advisor to the World Health Organization (WHO) Hereditary Diseases Program, and as a member of the WHO's Expert
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Over a period of more than 30 years, Caskey has served as a member or chair of the scientific advisory boards of more than a dozen bio-medical corporations, largely focused on human genetics and related gene therapies for muscular dystrophy and other neuro-muscular diseases. He was a Fellow of the
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Caskey's research over a period of more than 50 years has focused on the genetic basis of human diseases and their molecular diagnosis. He discovered the molecular basis of disease "anticipation" as an expansion of short tandem repeat DNA sequences causative of FragileX, Myotonic Dystrophy, Ataxia,
246:, where he served as Chairman for the next two decades. At Baylor he served as Chief, Section of Medical Genetics (1971–85) and Professor of Medicine and Biochemistry (1971–94). From 1976 to 1994 Caskey was an Investigator at the 178: 305:
In recent years, his work has also involved cooperation with biomedical researchers in the Taizhou Cardiovascular R&D Centre and the Guangshou Institute of Biomedicine and Health (GIBH),
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of Cogene Biotech Ventures and Cogene Ventures, venture capital funds designed to support early-stage biotechnology and life sciences companies using genome technology for drug discovery.
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and was first to establish the undiagnosed disease program of children. For his service to genomics research in Canada he was made a Fellow of the Academy of Science of the
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Nuevo LeΓ³n Award for Cooperation in Education and Investigation (2009) and the "Flame of Truth" award for backing up biotechnology's development in Mexico (2014).
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In 2006, Caskey was appointed director and CEO-elect of the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, part of the
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Caskey has had a long engagement with medical science in other countries, notably Canada, Mexico and China. From 2002 to 2009 he was a member of the Board of
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In 1994 Caskey left academia to become senior vice president for research at Merck Pharmaceuticals and Vaccines. He was trustee and president of The
731: 686: 655: 711: 629: 721: 513: 646: 370:, a medical technology company based in San Diego, using artificial intelligence to prevent diseases associated with aging. 215:. Caskey received his M.D. degree in 1963 and completed internship and residency in the Department of Medicine (1963–65). 334: 137: 314: 247: 326: 696: 691: 254: 224: 261:. He has trained 67 Post-Doctoral Fellows and 25 Doctoral graduates. He has published 480 academic papers. 227:(NIH) (1965 -1971) where he was a research associate at the National Heart and Lung Institute (NHLI) with 200: 66: 306: 239: 162: 108: 338: 171: 42: 650: 161:
and biomedical researcher and entrepreneur. He was a Professor of Molecular and Human Genetics at
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at Baylor. While on sabbatical leave from Baylor in 1979–80, Caskey was a Faculty Scholar at the
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Research Institute at the Merck Research Laboratories in Sumneytown Pike, West Point,
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In 1971, Caskey left NIH to found the Department of Molecular and Human Genetics at
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EDITOR OF THE ANNUAL REVIEW OF MEDICINE - VOLUME 70, 2019  : C. Thomas Caskey
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and from 2009 to 2012 he served as Chair of that organization. During his tenure,
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C. Thomas Caskey Will Direct Brown Foundation Institute of Molecular Medicine
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Medical School (1958–63). He was a student biochemical fellow (1961–62) with
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Casked served as director of the Joint Postdoctoral Program between the
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In 2019, Caskey took up a new role as Chief Medical Officer of
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from 2001 to 2019. He was a member of the editorial boards of
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In 2000, Caskey returned to Houston as founding director and
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Members of the United States National Academy of Sciences
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Baylor College of Medicine physicians and researchers
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Academy of Medicine, Engineering and Science of Texas
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University of Texas Health Science Center at Houston
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University of Texas Health Science Center at Houston
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and numerous other medical and scientific journals.
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American Association for the Advancement of Science
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From 1990 to 1991 he served as president of the 663: 717:Fellows of the American Academy of Microbiology 179:Proceedings of the National Academy of Sciences 640: 341:(1988-1990) and in 2004–05, President of the 727:Members of the National Academy of Medicine 658:, announcement by UT Health Science Center 574:"EW Healthcare Partners Team - Tom Caskey" 514:"Profile - Weill Cornell Medicine - Qatar" 702:Duke University School of Medicine alumni 412: 386: 482:"C Thomas Caskey, MD, FACP, FACMG, FRSC" 185:, the Encyclopedia of Molecular Medicine 664: 732:People from Lancaster, South Carolina 687:American health care chief executives 508: 506: 504: 502: 476: 474: 472: 470: 468: 257:unit with another Nobel Prize-winner 568: 566: 541: 539: 537: 535: 533: 323:American College of Medical Genetics 712:Howard Hughes Medical Investigators 13: 722:Annual Reviews (publisher) editors 499: 465: 349:Advisory Panel on Human Genetics. 335:American Society of Human Genetics 138:American Society of Human Genetics 14: 743: 563: 530: 315:American Society of Microbiology 128: 248:Howard Hughes Medical Institute 16:American geneticist (1938–2022) 614: 590: 437: 389:"C. Thomas Caskey (1938–2022)" 380: 327:American College of Physicians 1: 387:Witkowski, Jan (2022-03-11). 373: 225:National Institutes of Health 201:University of South Carolina 194: 67:University of South Carolina 7: 307:Chinese Academy of Sciences 10: 748: 647:Curriculum Vitae of Caskey 641:External links and sources 414:10.1038/d41586-022-00714-2 240:Baylor College of Medicine 163:Baylor College of Medicine 109:Baylor College of Medicine 339:Human Genome Organization 218: 172:Annual Review of Medicine 127: 122: 114: 104: 96: 89: 76: 62: 50: 43:Lancaster, South Carolina 28: 21: 255:Medical Research Council 134:2021 William Allan Award 518:qatar-weill.cornell.edu 331:Royal Society of Canada 292:Royal Society of Canada 157:who has been a medical 626:www.humanlongevity.com 147:Charles Thomas Caskey 697:American geneticists 692:American biochemists 578:www.ewhealthcare.com 252:Cambridge University 199:Caskey attended the 602:alliedacademies.com 405:2022Natur.603..386W 337:, President of the 209:James B. Wyngaarden 100:Biomedical genetics 81:William Allan Award 649:on the website of 233:Marshall Nirenberg 223:Caskey trained at 153:, was an American 39:September 12, 1938 551:www.bloomberg.com 547:"C Thomas Caskey" 213:metabolic disease 165:, and served as 144: 143: 118: 117: 91:Scientific career 739: 634: 633: 628:. Archived from 618: 612: 611: 609: 608: 594: 588: 587: 585: 584: 570: 561: 560: 558: 557: 543: 528: 527: 525: 524: 510: 497: 496: 494: 492: 478: 463: 462: 457: 455: 441: 435: 434: 416: 384: 151:C. Thomas Caskey 132: 131: 120: 119: 85: 57: 54:January 13, 2022 38: 36: 23:C. Thomas Caskey 19: 18: 747: 746: 742: 741: 740: 738: 737: 736: 662: 661: 643: 638: 637: 620: 619: 615: 606: 604: 596: 595: 591: 582: 580: 572: 571: 564: 555: 553: 545: 544: 531: 522: 520: 512: 511: 500: 490: 488: 480: 479: 466: 453: 451: 443: 442: 438: 385: 381: 376: 368:Human Longevity 286:discovered the 221: 205:Duke University 197: 129: 123:External videos 83: 71:Duke University 69: 63:Alma mater 55: 46: 40: 34: 32: 24: 17: 12: 11: 5: 745: 735: 734: 729: 724: 719: 714: 709: 704: 699: 694: 689: 684: 679: 674: 660: 659: 653: 642: 639: 636: 635: 632:on 2020-07-22. 613: 589: 562: 529: 498: 464: 449:Annual Reviews 436: 378: 377: 375: 372: 259:Sydney Brenner 244:Houston, Texas 220: 217: 203:(1956–58) and 196: 193: 142: 141: 125: 124: 116: 115: 112: 111: 106: 102: 101: 98: 94: 93: 87: 86: 78: 74: 73: 64: 60: 59: 58:(aged 83) 52: 48: 47: 41: 30: 26: 25: 22: 15: 9: 6: 4: 3: 2: 744: 733: 730: 728: 725: 723: 720: 718: 715: 713: 710: 708: 705: 703: 700: 698: 695: 693: 690: 688: 685: 683: 680: 678: 675: 673: 670: 669: 667: 657: 654: 652: 648: 645: 644: 631: 627: 623: 617: 603: 599: 593: 579: 575: 569: 567: 552: 548: 542: 540: 538: 536: 534: 519: 515: 509: 507: 505: 503: 487: 483: 477: 475: 473: 471: 469: 461: 450: 446: 440: 432: 428: 424: 420: 415: 410: 406: 402: 399:(7901): 386. 398: 394: 390: 383: 379: 371: 369: 364: 362: 357: 355: 350: 346: 344: 340: 336: 332: 328: 324: 320: 316: 310: 308: 303: 300: 295: 293: 289: 285: 284:Genome Canada 281: 280:Genome Canada 276: 274: 270: 267: 262: 260: 256: 253: 249: 245: 241: 236: 234: 230: 226: 216: 214: 210: 206: 202: 192: 188: 186: 184: 180: 174: 173: 168: 164: 160: 156: 152: 148: 139: 135: 126: 121: 113: 110: 107: 103: 99: 95: 92: 88: 82: 79: 75: 72: 68: 65: 61: 53: 49: 44: 31: 27: 20: 630:the original 625: 616: 605:. 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Retrieved 448: 439: 396: 392: 382: 365: 358: 351: 347: 311: 304: 296: 277: 273:Pennsylvania 263: 237: 222: 198: 189: 176: 170: 150: 146: 145: 105:Institutions 90: 56:(2022-01-13) 677:2022 deaths 672:1938 births 486:www.bcm.edu 229:Nobel Prize 666:Categories 651:Identigene 607:2021-05-25 583:2021-05-25 556:2021-05-25 523:2021-05-25 491:9 December 374:References 288:SARS Virus 159:Geneticist 35:1938-09-12 431:247407254 294:in 2010. 195:Education 155:internist 423:35277690 329:and the 231:-winner 401:Bibcode 183:Science 169:of the 140:, 2021. 429:  421:  393:Nature 321:, the 317:, the 269:Genome 219:Career 167:editor 97:Fields 84:(2021) 77:Awards 45:, U.S. 427:S2CID 266:Merck 493:2019 456:2021 419:PMID 325:the 177:the 51:Died 29:Born 409:doi 397:603 354:CEO 242:in 136:, 668:: 624:. 600:. 576:. 565:^ 549:. 532:^ 516:. 501:^ 484:. 467:^ 458:. 447:. 425:. 417:. 407:. 395:. 391:. 345:. 309:. 275:. 181:, 610:. 586:. 559:. 526:. 495:. 433:. 411:: 403:: 37:) 33:(

Index

Lancaster, South Carolina
University of South Carolina
Duke University
William Allan Award
Baylor College of Medicine
2021 William Allan Award
American Society of Human Genetics
internist
Geneticist
Baylor College of Medicine
editor
Annual Review of Medicine
Proceedings of the National Academy of Sciences
Science
University of South Carolina
Duke University
James B. Wyngaarden
metabolic disease
National Institutes of Health
Nobel Prize
Marshall Nirenberg
Baylor College of Medicine
Houston, Texas
Howard Hughes Medical Institute
Cambridge University
Medical Research Council
Sydney Brenner
Merck
Genome
Pennsylvania

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