355:
332:
254:
229:
3318:
3348:
3333:
606:
3363:
361:
260:
3303:
3288:
42:
1588:
that may be involved in the negative cross-talk between adipose tissue and skeletal muscle. CCL2 impairs insulin signaling in skeletal muscle cells via ERK1/2 activation at doses similar to its physiological plasma concentrations (200 pg/mL), but does not involve activation of the NF-κB pathway. CCL2
1453:
CCL2 exhibits a chemotactic activity for monocytes and basophils. However, it does not attract neutrophils or eosinophils. After deletion of the N-terminal residue, CCL2 loses its attractivity for basophils and becomes a chemoattractant of eosinophils. Basophils and mast cells that are treated with
2036:
McDermott DH, Yang Q, Kathiresan S, Cupples LA, Massaro JM, Keaney JF, Larson MG, Vasan RS, Hirschhorn JN, O'Donnell CJ, Murphy PM, Benjamin EJ (August 2005). "CCL2 polymorphisms are associated with serum monocyte chemoattractant protein-1 levels and myocardial infarction in the
Framingham Heart
1496:
The CCL2 chemokine is also expressed by neurons, astrocytes and microglia. The expression of CCL2 in neurons is mainly found in the cerebral cortex, globus pallidus, hippocampus, paraventricular and supraoptic hypothalamic nuclei, lateral hypothalamus, substantia nigra, facial nuclei, motor and
2409:
Banisadr G, Gosselin RD, Mechighel P, Kitabgi P, Rostène W, Parsadaniantz SM (August 2005). "Highly regionalized neuronal expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) in rat brain: evidence for its colocalization with neurotransmitters and neuropeptides".
68:
1454:
CCL2 release their granules to the intercellular space. This effect can be also potentiated by a pre-treatment with IL-3 or even by other cytokines. CCL2 augments monocyte anti-tumor activity and it is essential for formation of granulomas. CCL2 protein become a
3018:
Chandrakala AN, Sukul D, Selvarajan K, Sai-Sudhakar C, Sun B, Parthasarathy S (January 2012). "Induction of brain natriuretic peptide and monocyte chemotactic protein-1 gene expression by oxidized low-density lipoprotein: relevance to ischemic heart failure".
1546:
Hypomethylation of CpG sites within the CCL2 promoter region is affected by high levels of blood glucose and TG, which increase CCL2 levels in the blood serum. The later plays an important role in the vascular complications of type 2 diabetes.
2313:"Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx"
1403:
In humans, the levels of CCL2 can vary considerably. In the white people of
European descent, the multivariable-adjusted heritability of CCL2 concentrations is as much as 0.37 in the blood plasma and 0.44 - in the serum.
2682:
Kim JS, Gautam SC, Chopp M, Zaloga C, Jones ML, Ward PA, Welch KM (February 1995). "Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat".
3062:
Cuesta S, Kireev R, Forman K, García C, Escames G, Ariznavarreta C, Vara E, Tresguerres JA (December 2010). "Melatonin improves inflammation processes in liver of senescence-accelerated prone male mice (SAMP8)".
368:
267:
2498:"RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis"
1861:
Xu LL, Warren MK, Rose WL, Gong W, Wang JM (September 1996). "Human recombinant monocyte chemotactic protein and other C-C chemokines bind and induce directional migration of dendritic cells in vitro".
2362:"MCP-1 is induced by receptor activator of nuclear factor-κB ligand, promotes human osteoclast fusion, and rescues granulocyte macrophage colony-stimulating factor suppression of osteoclast formation"
1531:
CCL2 is involved in the neuroinflammatory processes that takes place in the various diseases of the central nervous system (CNS), which are characterized by neuronal degeneration. CCL2 expression in
3317:
3347:
1942:"Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE"
2873:
Liu ZH, Chen LL, Deng XL, Song HJ, Liao YF, Zeng TS, Zheng J, Li HQ (June 2012). "Methylation status of CpG sites in the MCP-1 promoter is correlated to serum MCP-1 in Type 2 diabetes".
3332:
1593:. CCL2 may represent a molecular link in the negative cross-talk between adipose tissue and skeletal muscle assigning a completely novel important role to CCL2 besides inflammation.
1905:
Mehrabian M, Sparkes RS, Mohandas T, Fogelman AM, Lusis AJ (January 1991). "Localization of monocyte chemotactic protein-1 gene (SCYA2) to human chromosome 17q11.2-q21.1".
4518:
1064:
1045:
190:
3907:
3362:
3171:
Wahl SM, Greenwell-Wild T, Hale-Donze H, Moutsopoulos N, Orenstein JM (September 2000). "Permissive factors for HIV-1 infection of macrophages".
2920:"MCP-1 upregulates amylin expression in murine pancreatic β cells through ERK/JNK-AP1 and NF-κB related signaling pathways independent of CCR2"
2082:"Circulating MCP-1 levels shows linkage to chemokine receptor gene cluster on chromosome 3: the NHLBI family heart study follow-up examination"
5546:
5153:
3979:
1727:
2221:
Conti P, Boucher W, Letourneau R, Feliciani C, Reale M, Barbacane RC, Vlagopoulos P, Bruneau G, Thibault J, Theoharides TC (November 1995).
1709:
4823:
5193:
5188:
5178:
5173:
5168:
5148:
5093:
5088:
5078:
5063:
4511:
5395:
5234:
1264:
3109:
2875:
1536:
1271:
5375:
3983:
5266:
4504:
4378:
2080:
Bielinski SJ, Pankow JS, Miller MB, Hopkins PN, Eckfeldt JH, Hixson J, Liu Y, Register T, Myers RH, Arnett DK (December 2007).
5571:
3267:
3153:
1379:(17q11.2-q21.1). The gene span is 1,927 bases and the CCL2 gene resides on the Watson (plus) strand. The CCL2 gene has three
2979:"Monocyte chemotactic protein-1 is a potential player in the negative cross-talk between adipose tissue and skeletal muscle"
1692:
65:
3326:: SOLUTION STRUCTURE OF THE MONOCYTE CHEMOATTRACTANT PROTEIN-1 DIMER USING HETERONUCLEAR, NMR, MINIMIZED AVERAGE STRUCTURE
3115:
3403:
3356:: VIRAL CHEMOKINE BINDING PROTEIN M3 FROM MURINE GAMMAHERPESVIRUS68 IN COMPLEX WITH THE P8A VARIANT OF CC-CHEMOKINE MCP-1
1671:
1478:
3302:
3287:
2590:"Chemokine CCL2 and its receptor CCR2 are increased in the hippocampus following pilocarpine-induced status epilepticus"
1528:
reduces infiltration of macrophages and T cells, reduces crescent formation, as well as scarring and renal impairment.
354:
4269:
1997:
Furutani Y, Nomura H, Notake M, Oyamada Y, Fukui T, Yamada M, Larsen CG, Oppenheim JJ, Matsushima K (February 1989).
1578:. Amylin upregulation by CCL2 contributes to the elevation of the plasma amylin and insulin resistance in obesity.
331:
5477:
5468:
3799:
2777:"Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis"
1696:
1675:
1481:, multinuclear cells from M-CSF-treated monocytes in the absence of RANKL, but produced osteoclasts that lacked
1465:
CCL2 can be found at the sites of tooth eruption and bone degradation. In the bone, CCL2 is expressed by mature
1109:
2775:
Ransohoff RM, Hamilton TA, Tani M, Stoler MH, Shick HE, Major JA, Estes ML, Thomas DM, Tuohy VK (April 1993).
5390:
5271:
4958:
3576:
253:
228:
3341:: SOLUTION STRUCTURE OF THE MONOCYTE CHEMOATTRACTANT PROTEIN-1 DIMER USING HETERONUCLEAR, NMR, 20 STRUCTURES
2178:
Craig MJ, Loberg RD (December 2006). "CCL2 (Monocyte
Chemoattractant Protein-1) in cancer bone metastases".
1090:
170:
2826:"Role of CCL2 (MCP-1) in traumatic brain injury (TBI): evidence from severe TBI patients and CCL2-/- mice"
1607:
Treatment with melatonin in old mice with age related liver inflammation decreased the mRNA expression of
1477:(regulated on activation normal T cell expressed and secreted). Both MCP-1 and RANTES induce formation of
1395:. In turn, the mature CCL2 is 76 amino acids long. The CCL2 predicted weight is 11.025 kilodaltons (kDa).
4412:
3962:
3737:
1636:
1608:
1567:
4445:
4247:
3957:
367:
266:
4366:
4051:
3260:
1601:
1497:
spinal trigeminal nuclei, gigantocellular reticular nucleus and in
Purkinje cells in the cerebellum.
360:
259:
157:
4401:
3828:
3804:
1563:
178:
3208:
Sell H, Eckel J (June 2007). "Monocyte chemotactic protein-1 and its role in insulin resistance".
5034:
3396:
2639:
Fabene PF, Bramanti P, Constantin G (July 2010). "The emerging role for chemokines in epilepsy".
2496:
Lloyd CM, Minto AW, Dorf ME, Proudfoot A, Wells TN, Salant DJ, Gutierrez-Ramos JC (April 1997).
1999:"Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF)"
1247:
1226:
1200:
1179:
4538:
3729:
1747:"Single-cell analysis reveals chemokine-mediated differential regulation of monocyte mechanics"
1540:
2918:
Cai K, Qi D, Hou X, Wang O, Chen J, Deng B, Qian L, Liu X, Le Y (May 2011). Fadini GP (ed.).
1624:
242:
5419:
4255:
3253:
2931:
2223:"Monocyte chemotactic protein-1 provokes mast cell aggregation and [3H]5HT release"
1953:
1815:
1758:
1514:
1490:
795:
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
198:
8:
4097:
3121:
22:
2935:
1957:
1819:
1762:
1473:
and it is under control of nuclear factor κB (NFκB). In the human osteoclasts, CCL2 and
5576:
4530:
4527:
4264:
4221:
4136:
3843:
3389:
3233:
3196:
3088:
3044:
2954:
2919:
2900:
2850:
2825:
2806:
2752:
2727:
2708:
2664:
2616:
2589:
2570:
2522:
2497:
2478:
2435:
2391:
2342:
2288:
2263:
2239:
2222:
2203:
2155:
2130:
2111:
2062:
1979:
1887:
1779:
1746:
1525:
202:
161:, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF, C-C motif chemokine ligand 2
2050:
1745:
Evers TM, Sheikhhassani V, Haks MC, Storm C, Ottenhoff TH, Mashaghi A (January 2022).
979:
974:
969:
964:
959:
954:
949:
944:
939:
934:
929:
924:
919:
914:
909:
904:
899:
894:
889:
884:
879:
874:
869:
864:
859:
854:
849:
844:
839:
834:
829:
824:
819:
814:
809:
804:
799:
794:
789:
784:
779:
774:
769:
764:
759:
754:
749:
744:
739:
734:
729:
724:
719:
703:
698:
693:
677:
672:
667:
662:
657:
652:
647:
4128:
3747:
3613:
3225:
3188:
3159:
3149:
3080:
3036:
3000:
2959:
2892:
2855:
2798:
2757:
2700:
2696:
2656:
2621:
2562:
2527:
2470:
2427:
2383:
2334:
2293:
2244:
2195:
2160:
2103:
2054:
2018:
2014:
1971:
1966:
1941:
1922:
1918:
1879:
1843:
1838:
1803:
1784:
1459:
1425:
1388:
150:
58:
3237:
3200:
3136:
Yoshimura T, Leonard EJ (1991). "Human
Monocyte Chemoattractant Protein-1 (MCP-1)".
3092:
2904:
2810:
2712:
2574:
2482:
2439:
2395:
2346:
2207:
2066:
1891:
4440:
4361:
4229:
3918:
3752:
3217:
3180:
3141:
3072:
3048:
3028:
2990:
2949:
2939:
2884:
2845:
2837:
2788:
2747:
2739:
2692:
2668:
2652:
2648:
2611:
2601:
2588:
Foresti ML, Arisi GM, Katki K, Montañez A, Sanchez RM, Shapiro LA (December 2009).
2554:
2517:
2509:
2462:
2419:
2373:
2324:
2283:
2275:
2234:
2187:
2150:
2142:
2115:
2093:
2046:
2010:
1983:
1961:
1914:
1871:
1833:
1823:
1774:
1766:
1417:
447:
378:
322:
277:
182:
1940:
Yoshimura T, Yuhki N, Moore SK, Appella E, Lerman MI, Leonard EJ (February 1989).
3967:
3653:
3221:
2944:
2329:
2312:
1518:
1352:
422:
206:
26:
4496:
3145:
3140:. Advances in Experimental Medicine and Biology. Vol. 305. pp. 47–56.
3076:
2131:"The chemokine MCP-1 (CCL2) in the host interaction with cancer: a foe or ally?"
1732:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1714:
National Center for
Biotechnology Information, U.S. National Library of Medicine
4481:
4476:
4331:
4327:
4309:
4304:
4107:
4102:
4092:
4087:
4082:
4077:
4072:
4068:
4037:
4032:
4027:
4006:
4001:
3996:
3991:
3946:
3941:
3936:
3931:
3879:
3864:
3855:
3412:
3032:
2793:
2776:
2743:
1808:
Proceedings of the
National Academy of Sciences of the United States of America
1770:
1644:
1485:
expression and resorptive capacity. It is proposed that CCL2 and RANTES act as
1437:
1348:
523:
2466:
2191:
5565:
5158:
5068:
4746:
4471:
4466:
4461:
4407:
4356:
4022:
3926:
3902:
3897:
3874:
3869:
3860:
3851:
3633:
1597:
1421:
1376:
634:
605:
3381:
2098:
2081:
583:
461:
5520:
5454:
5013:
4818:
4639:
3952:
3784:
3229:
3192:
3084:
3040:
3004:
2963:
2896:
2859:
2841:
2824:
Semple BD, Bye N, Rancan M, Ziebell JM, Morganti-Kossmann MC (April 2010).
2761:
2660:
2625:
2606:
2566:
2513:
2474:
2431:
2387:
2378:
2361:
2338:
2311:
Dean RA, Cox JH, Bellac CL, Doucet A, Starr AE, Overall CM (October 2008).
2279:
2199:
2164:
2107:
2058:
1828:
1804:"Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant"
1788:
1372:
1356:
1340:
440:
219:
3163:
2802:
2704:
2531:
2297:
2248:
2022:
1975:
1926:
1883:
1847:
1311:
1306:
5488:
5385:
5301:
5286:
4649:
4373:
4319:
4060:
3819:
3742:
3184:
2995:
2978:
2264:"Monocyte chemotactic protein 1 is a potent activator of human basophils"
2146:
1875:
1482:
1413:
1154:
1135:
3170:
2728:"Mechanisms of mononuclear phagocyte recruitment in Alzheimer's disease"
1505:
CCL2 is implicated in pathogeneses of several diseases characterized by
41:
5405:
5365:
5291:
4833:
4426:
4119:
3809:
3769:
1470:
1466:
1433:
1392:
1343:
family. CCL2 tightly regulates cellular mechanics and thereby recruits
339:
236:
186:
3017:
2453:
Xia M, Sui Z (March 2009). "Recent developments in CCR2 antagonists".
2423:
127:
123:
119:
115:
111:
107:
103:
99:
95:
91:
87:
5276:
5244:
4828:
4813:
3431:
3371:: Crystal structure of human MCP-1 bound to a blocking antibody, 11K2
1648:
1585:
1581:
1532:
1510:
1486:
1360:
1009:
406:
393:
305:
292:
194:
1998:
5541:
5019:
4421:
3416:
1506:
1429:
1344:
1336:
1295:
2558:
1571:
1440:. Platelet derived growth factor is a major inducer of CCL2 gene.
1424:. CCL2 is anchored in the plasma membrane of endothelial cells by
4843:
2888:
1590:
1121:
1076:
994:
990:
905:
positive regulation of nitric-oxide synthase biosynthetic process
2545:
Gerard C, Rollins BJ (February 2001). "Chemokines and disease".
2408:
1904:
1647:
increased with melatonin treatment. Exogenous administration of
174:
5530:
5380:
5370:
5344:
5323:
5229:
5224:
4299:
4196:
4191:
4186:
4181:
4176:
4171:
3889:
3694:
3678:
3673:
3668:
3663:
3658:
3648:
3643:
2976:
2220:
1802:
Carr MW, Roth SJ, Luther E, Rose SS, Springer TA (April 1994).
1600:
and human myocytes with oxidized-LDL induced the expression of
1551:
1474:
1384:
1279:
1031:
614:
3245:
2261:
2035:
945:
negative regulation of vascular endothelial cell proliferation
5509:
5354:
5333:
5312:
5255:
5219:
5214:
5203:
5143:
5138:
5133:
5128:
5123:
5118:
5103:
5058:
5043:
4994:
4989:
4984:
4973:
4963:
4947:
4937:
4916:
4890:
4885:
4864:
4803:
4798:
4793:
4788:
4736:
4731:
4700:
4695:
4690:
4685:
4680:
4675:
4670:
4629:
4624:
4593:
4588:
4583:
4578:
4335:
4294:
4289:
4284:
4279:
4274:
4211:
4201:
4166:
4161:
4156:
4151:
4146:
4141:
3794:
3789:
3779:
3764:
3759:
3638:
3628:
3623:
3618:
3608:
3603:
3597:
3581:
3571:
3566:
3561:
3556:
3551:
3546:
3541:
3536:
3530:
3525:
3520:
3515:
3510:
3505:
3500:
3495:
1632:
1628:
1620:
1616:
1559:
1555:
1535:
is increased in epilepsy, brain ischemia
Alzheimer's disease
2079:
1428:
side chains of proteoglycans. CCL2 is primarily secreted by
950:
negative regulation of G1/S transition of mitotic cell cycle
5444:
5439:
5428:
4926:
4911:
4900:
4874:
4853:
4783:
4778:
4773:
4768:
4757:
4726:
4721:
4710:
4665:
4660:
4619:
4603:
4573:
4568:
4563:
4558:
4547:
4259:
4206:
3774:
3715:
3710:
3490:
3485:
3480:
3475:
3469:
3463:
3457:
3446:
2774:
2262:
Bischoff SC, Krieger M, Brunner T, Dahinden CA (May 1992).
1996:
1744:
1640:
1612:
1589:
significantly reduced insulin-stimulated glucose uptake in
1575:
1455:
1447:
1443:
1380:
975:
positive regulation of synaptic transmission, glutamatergic
2977:
Sell H, Dietze-Schroeder D, Kaiser U, Eckel J (May 2006).
1939:
2587:
955:
positive regulation of endothelial cell apoptotic process
3061:
2638:
1604:
and CCL2 genes, while native LDL (N-LDL) had no effect.
430:
2495:
980:
positive regulation of NMDA glutamate receptor activity
2823:
770:
cellular response to fibroblast growth factor stimulus
1635:
and NKAP in old male mice. The protein expression of
1524:
Administration of anti-CCL2 antibodies in a model of
730:
negative regulation of natural killer cell chemotaxis
595:
2681:
2310:
2003:
1375:, CCL2 and many other CC chemokines are located on
850:
negative regulation of glial cell apoptotic process
1801:
1688:
1686:
1684:
1667:
1665:
1663:
1420:of approximately 13-15 kDa depending on levels of
4526:
377:
276:
5563:
3135:
2725:
1860:
3021:American Journal of Physiology. Cell Physiology
2872:
1681:
1660:
1450:are two cell surface receptors that bind CCL2.
935:positive regulation of apoptotic cell clearance
720:negative regulation of neuron apoptotic process
2675:
2359:
1693:GRCm38: Ensembl release 89: ENSMUSG00000035352
4512:
3411:
3397:
3261:
2830:Journal of Cerebral Blood Flow and Metabolism
2732:CNS & Neurological Disorders Drug Targets
2544:
2073:
2029:
825:lipopolysaccharide-mediated signaling pathway
3311:: MONOCYTE CHEMOATTRACTANT PROTEIN 1, I-FORM
3296:: MONOCYTE CHEMOATTRACTANT PROTEIN 1, P-FORM
3055:
3011:
2970:
2917:
2911:
2866:
2171:
800:cellular response to organic cyclic compound
785:G protein-coupled receptor signaling pathway
755:positive regulation of ERK1 and ERK2 cascade
2255:
2214:
2177:
1990:
1738:
1672:GRCh38: Ensembl release 89: ENSG00000108691
4519:
4505:
3404:
3390:
3268:
3254:
2360:Kim MS, Day CJ, Morrison NA (April 2005).
1933:
1898:
1854:
1795:
1574:related signaling pathways independent of
930:cellular response to tumor necrosis factor
3207:
2994:
2953:
2943:
2876:Journal of Endocrinological Investigation
2849:
2792:
2768:
2751:
2615:
2605:
2521:
2377:
2328:
2287:
2238:
2154:
2128:
2097:
1965:
1837:
1827:
1778:
1537:experimental autoimmune encephalomyelitis
880:regulation of signaling receptor activity
865:positive regulation of calcium ion import
2402:
900:positive regulation of T cell activation
2719:
2581:
915:cellular response to lipopolysaccharide
855:PERK-mediated unfolded protein response
830:receptor signaling pathway via JAK-STAT
740:cell surface receptor signaling pathway
16:Mammalian protein found in Homo sapiens
5564:
2817:
2726:Hickman SE, El Khoury J (April 2010).
2632:
2538:
2489:
2452:
1500:
1398:
775:positive regulation of GTPase activity
5476:
4500:
3385:
3249:
2455:Expert Opinion on Therapeutic Patents
920:cellular response to interferon-gamma
382:
343:
338:
281:
240:
235:
2502:The Journal of Experimental Medicine
2412:The Journal of Comparative Neurology
2268:The Journal of Experimental Medicine
1407:
1359:produced by either tissue injury or
910:chemokine-mediated signaling pathway
5427:
2446:
2366:The Journal of Biological Chemistry
2353:
2135:Cellular & Molecular Immunology
940:cytokine-mediated signaling pathway
13:
3128:
1329:monocyte chemoattractant protein 1
925:cellular response to interleukin-1
704:intracellular anatomical structure
25:. For the diradical compound, see
14:
5588:
3102:
2051:10.1161/CIRCULATIONAHA.105.543579
1651:was able to reduce inflammation.
1458:antagonist when it is cleaved by
3361:
3346:
3331:
3316:
3301:
3286:
1391:contains a signal peptide of 23
604:
366:
359:
353:
330:
265:
258:
252:
227:
40:
4819:Cenicriviroc (TAK-652, TBR-652)
4640:Cenicriviroc (TAK-652, TBR-652)
3275:
2304:
2122:
673:CCR2 chemokine receptor binding
21:For the ICAO airport code, see
2653:10.1016/j.jneuroim.2010.05.016
1720:
1702:
1327:(CCL2) is also referred to as
1325:chemokine (C-C motif) ligand 2
678:CCR chemokine receptor binding
615:More reference expression data
584:More reference expression data
1:
3210:Current Opinion in Lipidology
2180:Cancer and Metastasis Reviews
1654:
351:
250:
5572:Genes on human chromosome 17
5159:Interleukin-8 (CXCL8, GCP-1)
5069:Interleukin-8 (CXCL8, GCP-1)
3222:10.1097/MOL.0b013e3281338546
3173:Journal of Leukocyte Biology
2945:10.1371/journal.pone.0019559
2697:10.1016/0165-5728(94)00138-e
2594:Journal of Neuroinflammation
2330:10.1182/blood-2007-12-129080
2015:10.1016/0006-291X(89)92430-3
1967:10.1016/0014-5793(89)80590-3
1919:10.1016/0888-7543(91)90239-B
1864:Journal of Leukocyte Biology
7:
3146:10.1007/978-1-4684-6009-4_6
3077:10.1016/j.exger.2010.08.016
1366:
1333:small inducible cytokine A2
890:helper T cell extravasation
550:subcutaneous adipose tissue
10:
5593:
3120:gene details page in the
3033:10.1152/ajpcell.00116.2011
2794:10.1096/fasebj.7.6.8472896
2744:10.2174/187152710791011982
2685:Journal of Neuroimmunology
2641:Journal of Neuroimmunology
2129:Yoshimura T (April 2018).
1771:10.1016/j.isci.2021.103555
970:sensory perception of pain
840:protein kinase B signaling
760:animal organ morphogenesis
648:signaling receptor binding
20:
5529:
5508:
5501:
5467:
5418:
5353:
5332:
5311:
5254:
5202:
5102:
5042:
5033:
5003:
4972:
4946:
4925:
4899:
4873:
4852:
4756:
4709:
4648:
4602:
4546:
4537:
4391:
4367:Colony-stimulating factor
4349:
4318:
4246:
4220:
4127:
4118:
4059:
4050:
4015:
3978:
3916:
3888:
3842:
3827:
3818:
3728:
3703:
3687:
3590:
3439:
3430:
3423:
3281:
2467:10.1517/13543770902755129
2192:10.1007/s10555-006-9027-x
1728:"Mouse PubMed Reference:"
1710:"Human PubMed Reference:"
1489:loop in human osteoclast
1310:
1305:
1301:
1294:
1278:
1259:
1244:
1240:
1223:
1219:
1212:
1197:
1193:
1176:
1172:
1165:
1152:
1148:
1133:
1129:
1120:
1107:
1103:
1088:
1084:
1075:
1062:
1058:
1043:
1039:
1030:
1015:
1008:
1004:
988:
870:cytoskeleton organization
633:
629:
612:
603:
594:
581:
530:
521:
468:
459:
429:
421:
417:
400:
387:
350:
329:
320:
316:
299:
286:
249:
226:
217:
213:
168:
165:
155:
148:
143:
84:
79:
62:
57:
52:
48:
39:
34:
4402:proinflammatory cytokine
3065:Experimental Gerontology
1272:Chr 11: 81.99 – 81.99 Mb
1265:Chr 17: 34.26 – 34.26 Mb
845:astrocyte cell migration
820:regulation of cell shape
725:viral genome replication
2099:10.1038/sj.gene.6364434
1643:was also decreased and
745:humoral immune response
735:protein phosphorylation
653:protein kinase activity
5194:Reparixin (repertaxin)
5094:Reparixin (repertaxin)
3533:/PARC/DCCK1/AMAC1/MIP4
2842:10.1038/jcbfm.2009.262
2607:10.1186/1742-2094-6-40
2514:10.1084/jem.185.7.1371
2379:10.1074/jbc.M412713200
2280:10.1084/jem.175.5.1271
1829:10.1073/pnas.91.9.3652
1541:traumatic brain injury
5445:Lymphotactin-β (XCL2)
5440:Lymphotactin-α (XCL1)
3138:Chemotactic Cytokines
1509:infiltrates, such as
965:lymphocyte chemotaxis
960:eosinophil chemotaxis
895:macrophage chemotaxis
885:neutrophil chemotaxis
835:response to bacterium
780:inflammatory response
558:stroma of bone marrow
345:Chromosome 11 (mouse)
243:Chromosome 17 (human)
5489:Fractalkine (CX3CL1)
5406:Plerixafor (AMD3100)
5292:Plerixafor (AMD3100)
3185:10.1189/jlb.68.3.303
3114:genome location and
2996:10.1210/en.2005-0969
2147:10.1038/cmi.2017.135
1876:10.1002/jlb.60.3.365
1515:rheumatoid arthritis
1412:CCL2 is a monomeric
1339:that belongs to the
765:cellular homeostasis
694:extracellular region
570:white adipose tissue
500:smooth muscle tissue
384:11 C|11 49.9 cM
80:List of PDB id codes
53:Available structures
4098:Interferon type III
3122:UCSC Genome Browser
2936:2011PLoSO...619559C
1958:1989FEBSL.244..487Y
1820:1994PNAS...91.3652C
1763:2022iSci...25j3555E
1596:Incubation of HL-1
1554:expression through
1501:Clinical importance
1399:Population genetics
875:signal transduction
790:monocyte chemotaxis
699:extracellular space
508:epithelium of colon
480:islet of Langerhans
23:Candle Lake Airpark
4528:Chemokine receptor
2086:Genes and Immunity
1526:glomerulonephritis
1335:. CCL2 is a small
1110:ENSMUSG00000035352
713:Biological process
687:Cellular component
668:chemokine activity
641:Molecular function
5559:
5558:
5555:
5554:
5521:CC (β) chemokines
5497:
5496:
5463:
5462:
5414:
5413:
5108:
5048:
5029:
5028:
4494:
4493:
4387:
4386:
4345:
4344:
4242:
4241:
4238:
4237:
4046:
4045:
3724:
3723:
3379:
3378:
3155:978-1-4684-6011-7
2547:Nature Immunology
2424:10.1002/cne.20598
1460:metalloproteinase
1426:glycosaminoglycan
1408:Molecular biology
1389:protein precursor
1321:
1320:
1317:
1316:
1290:
1289:
1255:
1254:
1234:
1233:
1208:
1207:
1187:
1186:
1161:
1160:
1142:
1141:
1116:
1115:
1097:
1096:
1071:
1070:
1052:
1051:
1000:
999:
658:cytokine activity
625:
624:
621:
620:
590:
589:
577:
576:
515:
514:
496:left uterine tube
413:
412:
312:
311:
139:
138:
135:
134:
63:Ortholog search:
5584:
5506:
5505:
5474:
5473:
5425:
5424:
5247:(against CXCL10)
5106:
5046:
5040:
5039:
4544:
4543:
4521:
4514:
4507:
4498:
4497:
4125:
4124:
4057:
4056:
3840:
3839:
3825:
3824:
3437:
3436:
3428:
3427:
3406:
3399:
3392:
3383:
3382:
3365:
3350:
3335:
3320:
3305:
3290:
3270:
3263:
3256:
3247:
3246:
3241:
3204:
3167:
3097:
3096:
3059:
3053:
3052:
3015:
3009:
3008:
2998:
2974:
2968:
2967:
2957:
2947:
2915:
2909:
2908:
2870:
2864:
2863:
2853:
2821:
2815:
2814:
2796:
2772:
2766:
2765:
2755:
2723:
2717:
2716:
2679:
2673:
2672:
2636:
2630:
2629:
2619:
2609:
2585:
2579:
2578:
2542:
2536:
2535:
2525:
2493:
2487:
2486:
2450:
2444:
2443:
2406:
2400:
2399:
2381:
2357:
2351:
2350:
2332:
2308:
2302:
2301:
2291:
2259:
2253:
2252:
2242:
2218:
2212:
2211:
2175:
2169:
2168:
2158:
2126:
2120:
2119:
2101:
2077:
2071:
2070:
2033:
2027:
2026:
1994:
1988:
1987:
1969:
1937:
1931:
1930:
1902:
1896:
1895:
1858:
1852:
1851:
1841:
1831:
1799:
1793:
1792:
1782:
1742:
1736:
1735:
1724:
1718:
1717:
1706:
1700:
1690:
1679:
1669:
1584:secrete various
1418:molecular weight
1355:to the sites of
1303:
1302:
1274:
1267:
1250:
1238:
1237:
1229:
1217:
1216:
1213:RefSeq (protein)
1203:
1191:
1190:
1182:
1170:
1169:
1146:
1145:
1127:
1126:
1101:
1100:
1082:
1081:
1056:
1055:
1037:
1036:
1006:
1005:
631:
630:
617:
608:
601:
600:
586:
566:efferent ductule
526:
524:Top expressed in
519:
518:
464:
462:Top expressed in
457:
456:
436:
435:
419:
418:
409:
396:
385:
370:
363:
357:
346:
334:
318:
317:
308:
295:
284:
269:
262:
256:
245:
231:
215:
214:
209:
207:CCL2 - orthologs
160:
153:
130:
77:
76:
71:
50:
49:
44:
32:
31:
5592:
5591:
5587:
5586:
5585:
5583:
5582:
5581:
5562:
5561:
5560:
5551:
5525:
5493:
5459:
5410:
5349:
5328:
5307:
5304:(against CXCR4)
5250:
5198:
5105:
5098:
5045:
5025:
5016:(against CCL11)
4999:
4968:
4942:
4921:
4895:
4869:
4848:
4752:
4705:
4644:
4598:
4533:
4525:
4495:
4490:
4456:
4435:
4393:
4383:
4341:
4314:
4234:
4216:
4114:
4042:
4011:
3974:
3912:
3884:
3835:
3833:
3831:
3814:
3720:
3699:
3683:
3586:
3419:
3410:
3380:
3375:
3372:
3366:
3357:
3351:
3342:
3336:
3327:
3321:
3312:
3306:
3297:
3291:
3277:
3274:
3244:
3156:
3131:
3129:Further reading
3105:
3100:
3060:
3056:
3016:
3012:
2975:
2971:
2916:
2912:
2871:
2867:
2822:
2818:
2773:
2769:
2724:
2720:
2680:
2676:
2637:
2633:
2586:
2582:
2543:
2539:
2494:
2490:
2451:
2447:
2407:
2403:
2372:(16): 16163–9.
2358:
2354:
2309:
2305:
2260:
2256:
2219:
2215:
2176:
2172:
2127:
2123:
2078:
2074:
2034:
2030:
1995:
1991:
1938:
1934:
1903:
1899:
1859:
1855:
1800:
1796:
1743:
1739:
1726:
1725:
1721:
1708:
1707:
1703:
1691:
1682:
1670:
1661:
1657:
1519:atherosclerosis
1503:
1491:differentiation
1438:dendritic cells
1410:
1401:
1369:
1353:dendritic cells
1312:View/Edit Mouse
1307:View/Edit Human
1270:
1263:
1260:Location (UCSC)
1246:
1225:
1199:
1178:
1091:ENSG00000108691
984:
815:immune response
708:
682:
663:protein binding
613:
582:
573:
568:
564:
560:
556:
552:
548:
544:
540:
536:
522:
511:
506:
502:
498:
494:
490:
486:
482:
478:
474:
460:
404:
391:
383:
373:
372:
371:
364:
344:
321:Gene location (
303:
290:
282:
272:
271:
270:
263:
241:
218:Gene location (
169:
156:
149:
86:
64:
30:
27:Dichlorocarbene
17:
12:
11:
5:
5590:
5580:
5579:
5574:
5557:
5556:
5553:
5552:
5550:
5549:
5544:
5535:
5533:
5527:
5526:
5524:
5523:
5514:
5512:
5503:
5499:
5498:
5495:
5494:
5492:
5491:
5482:
5480:
5471:
5465:
5464:
5461:
5460:
5458:
5457:
5448:
5447:
5442:
5433:
5431:
5422:
5416:
5415:
5412:
5411:
5409:
5408:
5399:
5398:
5393:
5391:SDF-1 (CXCL12)
5388:
5383:
5378:
5373:
5371:CXCL11 (I-TAC)
5368:
5359:
5357:
5351:
5350:
5348:
5347:
5338:
5336:
5330:
5329:
5327:
5326:
5317:
5315:
5309:
5308:
5306:
5305:
5295:
5294:
5289:
5280:
5279:
5274:
5272:SDF-1 (CXCL12)
5269:
5260:
5258:
5252:
5251:
5249:
5248:
5238:
5237:
5232:
5230:CXCL11 (I-TAC)
5227:
5225:CXCL10 (IP-10)
5222:
5217:
5208:
5206:
5200:
5199:
5197:
5196:
5191:
5182:
5181:
5176:
5171:
5162:
5161:
5156:
5151:
5146:
5141:
5136:
5131:
5126:
5121:
5112:
5110:
5100:
5099:
5097:
5096:
5091:
5082:
5081:
5072:
5071:
5066:
5061:
5052:
5050:
5037:
5031:
5030:
5027:
5026:
5024:
5023:
5022:(against CCL2)
5017:
5007:
5005:
5001:
5000:
4998:
4997:
4992:
4987:
4978:
4976:
4970:
4969:
4967:
4966:
4961:
4952:
4950:
4944:
4943:
4941:
4940:
4931:
4929:
4923:
4922:
4920:
4919:
4914:
4905:
4903:
4897:
4896:
4894:
4893:
4888:
4879:
4877:
4871:
4870:
4868:
4867:
4858:
4856:
4850:
4849:
4847:
4846:
4837:
4836:
4831:
4826:
4821:
4816:
4807:
4806:
4801:
4796:
4791:
4786:
4781:
4776:
4771:
4762:
4760:
4754:
4753:
4751:
4750:
4749:(against CCR4)
4740:
4739:
4734:
4729:
4724:
4715:
4713:
4707:
4706:
4704:
4703:
4698:
4693:
4688:
4683:
4678:
4673:
4668:
4663:
4654:
4652:
4646:
4645:
4643:
4642:
4633:
4632:
4627:
4622:
4617:
4608:
4606:
4600:
4599:
4597:
4596:
4591:
4586:
4581:
4576:
4571:
4566:
4561:
4552:
4550:
4541:
4535:
4534:
4524:
4523:
4516:
4509:
4501:
4492:
4491:
4489:
4488:
4487:
4486:
4485:
4484:
4479:
4474:
4469:
4464:
4454:
4450:
4449:
4448:
4443:
4433:
4424:
4418:
4417:
4416:
4415:
4410:
4397:
4395:
4389:
4388:
4385:
4384:
4382:
4381:
4376:
4371:
4370:
4369:
4364:
4353:
4351:
4347:
4346:
4343:
4342:
4340:
4339:
4324:
4322:
4316:
4315:
4313:
4312:
4307:
4302:
4297:
4292:
4287:
4282:
4277:
4272:
4267:
4262:
4252:
4250:
4248:Ig superfamily
4244:
4243:
4240:
4239:
4236:
4235:
4233:
4232:
4226:
4224:
4218:
4217:
4215:
4214:
4209:
4204:
4199:
4194:
4189:
4184:
4179:
4174:
4169:
4164:
4159:
4154:
4149:
4144:
4139:
4133:
4131:
4122:
4116:
4115:
4113:
4112:
4111:
4110:
4105:
4095:
4090:
4085:
4080:
4075:
4065:
4063:
4054:
4048:
4047:
4044:
4043:
4041:
4040:
4035:
4030:
4025:
4019:
4017:
4013:
4012:
4010:
4009:
4004:
3999:
3994:
3988:
3986:
3976:
3975:
3973:
3972:
3971:
3970:
3965:
3960:
3955:
3944:
3939:
3934:
3929:
3923:
3921:
3914:
3913:
3911:
3910:
3905:
3900:
3894:
3892:
3886:
3885:
3883:
3882:
3877:
3872:
3867:
3858:
3848:
3846:
3837:
3822:
3816:
3815:
3813:
3812:
3807:
3802:
3797:
3792:
3787:
3782:
3777:
3772:
3767:
3762:
3757:
3756:
3755:
3750:
3740:
3734:
3732:
3726:
3725:
3722:
3721:
3719:
3718:
3713:
3707:
3705:
3701:
3700:
3698:
3697:
3691:
3689:
3685:
3684:
3682:
3681:
3676:
3671:
3666:
3661:
3656:
3651:
3646:
3641:
3636:
3631:
3626:
3621:
3616:
3611:
3606:
3601:
3594:
3592:
3588:
3587:
3585:
3584:
3579:
3574:
3569:
3564:
3559:
3554:
3549:
3544:
3539:
3534:
3528:
3523:
3518:
3513:
3508:
3503:
3498:
3493:
3488:
3483:
3478:
3473:
3467:
3461:
3455:
3449:
3443:
3441:
3434:
3425:
3421:
3420:
3413:Cell signaling
3409:
3408:
3401:
3394:
3386:
3377:
3376:
3374:
3373:
3367:
3360:
3358:
3352:
3345:
3343:
3337:
3330:
3328:
3322:
3315:
3313:
3307:
3300:
3298:
3292:
3285:
3282:
3279:
3278:
3273:
3272:
3265:
3258:
3250:
3243:
3242:
3205:
3168:
3154:
3132:
3130:
3127:
3126:
3125:
3104:
3103:External links
3101:
3099:
3098:
3054:
3027:(1): C165-77.
3010:
2989:(5): 2458–67.
2969:
2910:
2865:
2816:
2787:(6): 592–600.
2767:
2718:
2674:
2631:
2580:
2537:
2508:(7): 1371–80.
2488:
2461:(3): 295–303.
2445:
2401:
2352:
2323:(8): 3455–64.
2303:
2254:
2213:
2170:
2141:(4): 335–345.
2121:
2072:
2045:(8): 1113–20.
2028:
1989:
1932:
1897:
1853:
1794:
1737:
1719:
1701:
1680:
1658:
1656:
1653:
1598:cardiomyocytes
1502:
1499:
1409:
1406:
1400:
1397:
1368:
1365:
1349:memory T cells
1319:
1318:
1315:
1314:
1309:
1299:
1298:
1292:
1291:
1288:
1287:
1285:
1283:
1276:
1275:
1268:
1261:
1257:
1256:
1253:
1252:
1242:
1241:
1235:
1232:
1231:
1221:
1220:
1214:
1210:
1209:
1206:
1205:
1195:
1194:
1188:
1185:
1184:
1174:
1173:
1167:
1163:
1162:
1159:
1158:
1150:
1149:
1143:
1140:
1139:
1131:
1130:
1124:
1118:
1117:
1114:
1113:
1105:
1104:
1098:
1095:
1094:
1086:
1085:
1079:
1073:
1072:
1069:
1068:
1060:
1059:
1053:
1050:
1049:
1041:
1040:
1034:
1028:
1027:
1022:
1017:
1013:
1012:
1002:
1001:
998:
997:
986:
985:
983:
982:
977:
972:
967:
962:
957:
952:
947:
942:
937:
932:
927:
922:
917:
912:
907:
902:
897:
892:
887:
882:
877:
872:
867:
862:
857:
852:
847:
842:
837:
832:
827:
822:
817:
812:
807:
802:
797:
792:
787:
782:
777:
772:
767:
762:
757:
752:
747:
742:
737:
732:
727:
722:
716:
714:
710:
709:
707:
706:
701:
696:
690:
688:
684:
683:
681:
680:
675:
670:
665:
660:
655:
650:
644:
642:
638:
637:
627:
626:
623:
622:
619:
618:
610:
609:
598:
592:
591:
588:
587:
579:
578:
575:
574:
572:
571:
567:
563:
559:
555:
551:
547:
543:
539:
535:
531:
528:
527:
516:
513:
512:
510:
509:
505:
504:saphenous vein
501:
497:
493:
489:
485:
484:gastric mucosa
481:
477:
473:
469:
466:
465:
453:
452:
444:
433:
427:
426:
423:RNA expression
415:
414:
411:
410:
402:
398:
397:
389:
386:
381:
375:
374:
365:
358:
352:
348:
347:
342:
336:
335:
327:
326:
314:
313:
310:
309:
301:
297:
296:
288:
285:
280:
274:
273:
264:
257:
251:
247:
246:
239:
233:
232:
224:
223:
211:
210:
167:
163:
162:
154:
146:
145:
141:
140:
137:
136:
133:
132:
82:
81:
73:
72:
61:
55:
54:
46:
45:
37:
36:
15:
9:
6:
4:
3:
2:
5589:
5578:
5575:
5573:
5570:
5569:
5567:
5548:
5545:
5543:
5540:
5537:
5536:
5534:
5532:
5528:
5522:
5519:
5516:
5515:
5513:
5511:
5507:
5504:
5500:
5490:
5487:
5484:
5483:
5481:
5479:
5475:
5472:
5470:
5466:
5456:
5453:
5450:
5449:
5446:
5443:
5441:
5438:
5435:
5434:
5432:
5430:
5426:
5423:
5421:
5417:
5407:
5404:
5401:
5400:
5397:
5394:
5392:
5389:
5387:
5384:
5382:
5379:
5377:
5374:
5372:
5369:
5367:
5364:
5361:
5360:
5358:
5356:
5352:
5346:
5343:
5340:
5339:
5337:
5335:
5331:
5325:
5322:
5319:
5318:
5316:
5314:
5310:
5303:
5300:
5297:
5296:
5293:
5290:
5288:
5285:
5282:
5281:
5278:
5275:
5273:
5270:
5268:
5265:
5262:
5261:
5259:
5257:
5253:
5246:
5243:
5240:
5239:
5236:
5233:
5231:
5228:
5226:
5223:
5221:
5218:
5216:
5213:
5210:
5209:
5207:
5205:
5201:
5195:
5192:
5190:
5187:
5184:
5183:
5180:
5177:
5175:
5172:
5170:
5167:
5164:
5163:
5160:
5157:
5155:
5152:
5150:
5147:
5145:
5142:
5140:
5137:
5135:
5132:
5130:
5127:
5125:
5122:
5120:
5117:
5114:
5113:
5111:
5109:
5101:
5095:
5092:
5090:
5087:
5084:
5083:
5080:
5077:
5074:
5073:
5070:
5067:
5065:
5062:
5060:
5057:
5054:
5053:
5051:
5049:
5041:
5038:
5036:
5032:
5021:
5018:
5015:
5012:
5009:
5008:
5006:
5002:
4996:
4993:
4991:
4988:
4986:
4983:
4980:
4979:
4977:
4975:
4971:
4965:
4962:
4960:
4957:
4954:
4953:
4951:
4949:
4945:
4939:
4936:
4933:
4932:
4930:
4928:
4924:
4918:
4915:
4913:
4910:
4907:
4906:
4904:
4902:
4898:
4892:
4889:
4887:
4884:
4881:
4880:
4878:
4876:
4872:
4866:
4863:
4860:
4859:
4857:
4855:
4851:
4845:
4842:
4839:
4838:
4835:
4832:
4830:
4827:
4825:
4822:
4820:
4817:
4815:
4812:
4809:
4808:
4805:
4802:
4800:
4797:
4795:
4792:
4790:
4787:
4785:
4782:
4780:
4779:CCL5 (RANTES)
4777:
4775:
4774:CCL4 (MIP-1β)
4772:
4770:
4769:CCL3 (MIP-1α)
4767:
4764:
4763:
4761:
4759:
4755:
4748:
4747:Mogamulizumab
4745:
4742:
4741:
4738:
4735:
4733:
4730:
4728:
4727:CCL5 (RANTES)
4725:
4723:
4722:CCL3 (MIP-1α)
4720:
4717:
4716:
4714:
4712:
4708:
4702:
4699:
4697:
4694:
4692:
4689:
4687:
4684:
4682:
4679:
4677:
4674:
4672:
4669:
4667:
4664:
4662:
4661:CCL5 (RANTES)
4659:
4656:
4655:
4653:
4651:
4647:
4641:
4638:
4635:
4634:
4631:
4628:
4626:
4623:
4621:
4618:
4616:
4613:
4610:
4609:
4607:
4605:
4601:
4595:
4592:
4590:
4587:
4585:
4582:
4580:
4577:
4575:
4572:
4570:
4567:
4565:
4564:CCL5 (RANTES)
4562:
4560:
4559:CCL4 (MIP-1β)
4557:
4554:
4553:
4551:
4549:
4545:
4542:
4540:
4536:
4532:
4529:
4522:
4517:
4515:
4510:
4508:
4503:
4502:
4499:
4483:
4480:
4478:
4475:
4473:
4470:
4468:
4465:
4463:
4460:
4459:
4458:
4451:
4447:
4444:
4442:
4439:
4438:
4437:
4430:
4429:
4428:
4425:
4423:
4420:
4419:
4414:
4411:
4409:
4406:
4405:
4404:
4403:
4399:
4398:
4396:
4390:
4380:
4377:
4375:
4372:
4368:
4365:
4363:
4360:
4359:
4358:
4357:Hematopoietic
4355:
4354:
4352:
4348:
4337:
4333:
4329:
4326:
4325:
4323:
4321:
4317:
4311:
4308:
4306:
4303:
4301:
4298:
4296:
4293:
4291:
4288:
4286:
4283:
4281:
4278:
4276:
4273:
4271:
4268:
4266:
4263:
4261:
4257:
4254:
4253:
4251:
4249:
4245:
4231:
4228:
4227:
4225:
4223:
4219:
4213:
4210:
4208:
4205:
4203:
4200:
4198:
4195:
4193:
4190:
4188:
4185:
4183:
4180:
4178:
4175:
4173:
4170:
4168:
4165:
4163:
4160:
4158:
4155:
4153:
4150:
4148:
4145:
4143:
4140:
4138:
4135:
4134:
4132:
4130:
4126:
4123:
4121:
4117:
4109:
4106:
4104:
4101:
4100:
4099:
4096:
4094:
4091:
4089:
4086:
4084:
4081:
4079:
4076:
4074:
4070:
4067:
4066:
4064:
4062:
4058:
4055:
4053:
4049:
4039:
4036:
4034:
4031:
4029:
4026:
4024:
4021:
4020:
4018:
4014:
4008:
4005:
4003:
4000:
3998:
3995:
3993:
3990:
3989:
3987:
3985:
3981:
3977:
3969:
3966:
3964:
3961:
3959:
3956:
3954:
3950:
3949:
3948:
3945:
3943:
3940:
3938:
3935:
3933:
3930:
3928:
3925:
3924:
3922:
3920:
3915:
3909:
3906:
3904:
3901:
3899:
3896:
3895:
3893:
3891:
3887:
3881:
3878:
3876:
3873:
3871:
3868:
3866:
3862:
3859:
3857:
3853:
3850:
3849:
3847:
3845:
3841:
3838:
3830:
3826:
3823:
3821:
3817:
3811:
3808:
3806:
3803:
3801:
3798:
3796:
3793:
3791:
3788:
3786:
3783:
3781:
3778:
3776:
3773:
3771:
3768:
3766:
3765:TNFSF5/CD40LG
3763:
3761:
3758:
3754:
3751:
3749:
3746:
3745:
3744:
3741:
3739:
3736:
3735:
3733:
3731:
3727:
3717:
3714:
3712:
3709:
3708:
3706:
3702:
3696:
3693:
3692:
3690:
3686:
3680:
3677:
3675:
3672:
3670:
3667:
3665:
3662:
3660:
3657:
3655:
3652:
3650:
3647:
3645:
3642:
3640:
3637:
3635:
3632:
3630:
3627:
3625:
3622:
3620:
3617:
3615:
3612:
3610:
3607:
3605:
3602:
3599:
3596:
3595:
3593:
3589:
3583:
3580:
3578:
3575:
3573:
3570:
3568:
3565:
3563:
3560:
3558:
3555:
3553:
3550:
3548:
3545:
3543:
3540:
3538:
3535:
3532:
3529:
3527:
3524:
3522:
3519:
3517:
3514:
3512:
3509:
3507:
3504:
3502:
3499:
3497:
3494:
3492:
3489:
3487:
3484:
3482:
3479:
3477:
3474:
3471:
3468:
3465:
3462:
3459:
3456:
3453:
3450:
3448:
3445:
3444:
3442:
3438:
3435:
3433:
3429:
3426:
3422:
3418:
3414:
3407:
3402:
3400:
3395:
3393:
3388:
3387:
3384:
3370:
3364:
3359:
3355:
3349:
3344:
3340:
3334:
3329:
3325:
3319:
3314:
3310:
3304:
3299:
3295:
3289:
3284:
3283:
3280:
3271:
3266:
3264:
3259:
3257:
3252:
3251:
3248:
3239:
3235:
3231:
3227:
3223:
3219:
3216:(3): 258–62.
3215:
3211:
3206:
3202:
3198:
3194:
3190:
3186:
3182:
3179:(3): 303–10.
3178:
3174:
3169:
3165:
3161:
3157:
3151:
3147:
3143:
3139:
3134:
3133:
3123:
3119:
3118:
3113:
3112:
3107:
3106:
3094:
3090:
3086:
3082:
3078:
3074:
3071:(12): 950–6.
3070:
3066:
3058:
3050:
3046:
3042:
3038:
3034:
3030:
3026:
3022:
3014:
3006:
3002:
2997:
2992:
2988:
2984:
2983:Endocrinology
2980:
2973:
2965:
2961:
2956:
2951:
2946:
2941:
2937:
2933:
2930:(5): e19559.
2929:
2925:
2921:
2914:
2906:
2902:
2898:
2894:
2890:
2886:
2882:
2878:
2877:
2869:
2861:
2857:
2852:
2847:
2843:
2839:
2836:(4): 769–82.
2835:
2831:
2827:
2820:
2812:
2808:
2804:
2800:
2795:
2790:
2786:
2782:
2781:FASEB Journal
2778:
2771:
2763:
2759:
2754:
2749:
2745:
2741:
2738:(2): 168–73.
2737:
2733:
2729:
2722:
2714:
2710:
2706:
2702:
2698:
2694:
2691:(2): 127–34.
2690:
2686:
2678:
2670:
2666:
2662:
2658:
2654:
2650:
2647:(1–2): 22–7.
2646:
2642:
2635:
2627:
2623:
2618:
2613:
2608:
2603:
2599:
2595:
2591:
2584:
2576:
2572:
2568:
2564:
2560:
2559:10.1038/84209
2556:
2553:(2): 108–15.
2552:
2548:
2541:
2533:
2529:
2524:
2519:
2515:
2511:
2507:
2503:
2499:
2492:
2484:
2480:
2476:
2472:
2468:
2464:
2460:
2456:
2449:
2441:
2437:
2433:
2429:
2425:
2421:
2418:(3): 275–92.
2417:
2413:
2405:
2397:
2393:
2389:
2385:
2380:
2375:
2371:
2367:
2363:
2356:
2348:
2344:
2340:
2336:
2331:
2326:
2322:
2318:
2314:
2307:
2299:
2295:
2290:
2285:
2281:
2277:
2274:(5): 1271–5.
2273:
2269:
2265:
2258:
2250:
2246:
2241:
2236:
2233:(3): 434–40.
2232:
2228:
2224:
2217:
2209:
2205:
2201:
2197:
2193:
2189:
2185:
2181:
2174:
2166:
2162:
2157:
2152:
2148:
2144:
2140:
2136:
2132:
2125:
2117:
2113:
2109:
2105:
2100:
2095:
2092:(8): 684–90.
2091:
2087:
2083:
2076:
2068:
2064:
2060:
2056:
2052:
2048:
2044:
2040:
2032:
2024:
2020:
2016:
2012:
2009:(1): 249–55.
2008:
2004:
2000:
1993:
1985:
1981:
1977:
1973:
1968:
1963:
1959:
1955:
1952:(2): 487–93.
1951:
1947:
1943:
1936:
1928:
1924:
1920:
1916:
1912:
1908:
1901:
1893:
1889:
1885:
1881:
1877:
1873:
1870:(3): 365–71.
1869:
1865:
1857:
1849:
1845:
1840:
1835:
1830:
1825:
1821:
1817:
1814:(9): 3652–6.
1813:
1809:
1805:
1798:
1790:
1786:
1781:
1776:
1772:
1768:
1764:
1760:
1757:(1): 103555.
1756:
1752:
1748:
1741:
1733:
1729:
1723:
1715:
1711:
1705:
1698:
1694:
1689:
1687:
1685:
1677:
1673:
1668:
1666:
1664:
1659:
1652:
1650:
1646:
1642:
1638:
1634:
1630:
1626:
1622:
1618:
1614:
1610:
1605:
1603:
1599:
1594:
1592:
1587:
1583:
1579:
1577:
1573:
1569:
1565:
1561:
1557:
1553:
1550:CCL2 induces
1548:
1544:
1542:
1538:
1534:
1529:
1527:
1522:
1520:
1516:
1512:
1508:
1498:
1494:
1492:
1488:
1484:
1480:
1479:TRAP-positive
1476:
1472:
1468:
1463:
1461:
1457:
1451:
1449:
1445:
1441:
1439:
1435:
1431:
1427:
1423:
1422:glycosylation
1419:
1415:
1405:
1396:
1394:
1390:
1386:
1382:
1378:
1377:chromosome 17
1374:
1364:
1362:
1358:
1354:
1350:
1346:
1342:
1338:
1334:
1330:
1326:
1313:
1308:
1304:
1300:
1297:
1293:
1286:
1284:
1281:
1277:
1273:
1269:
1266:
1262:
1258:
1251:
1249:
1243:
1239:
1236:
1230:
1228:
1222:
1218:
1215:
1211:
1204:
1202:
1196:
1192:
1189:
1183:
1181:
1175:
1171:
1168:
1166:RefSeq (mRNA)
1164:
1157:
1156:
1151:
1147:
1144:
1138:
1137:
1132:
1128:
1125:
1123:
1119:
1112:
1111:
1106:
1102:
1099:
1093:
1092:
1087:
1083:
1080:
1078:
1074:
1067:
1066:
1061:
1057:
1054:
1048:
1047:
1042:
1038:
1035:
1033:
1029:
1026:
1023:
1021:
1018:
1014:
1011:
1007:
1003:
996:
992:
987:
981:
978:
976:
973:
971:
968:
966:
963:
961:
958:
956:
953:
951:
948:
946:
943:
941:
938:
936:
933:
931:
928:
926:
923:
921:
918:
916:
913:
911:
908:
906:
903:
901:
898:
896:
893:
891:
888:
886:
883:
881:
878:
876:
873:
871:
868:
866:
863:
861:
858:
856:
853:
851:
848:
846:
843:
841:
838:
836:
833:
831:
828:
826:
823:
821:
818:
816:
813:
811:
810:cell adhesion
808:
806:
803:
801:
798:
796:
793:
791:
788:
786:
783:
781:
778:
776:
773:
771:
768:
766:
763:
761:
758:
756:
753:
751:
748:
746:
743:
741:
738:
736:
733:
731:
728:
726:
723:
721:
718:
717:
715:
712:
711:
705:
702:
700:
697:
695:
692:
691:
689:
686:
685:
679:
676:
674:
671:
669:
666:
664:
661:
659:
656:
654:
651:
649:
646:
645:
643:
640:
639:
636:
635:Gene ontology
632:
628:
616:
611:
607:
602:
599:
597:
593:
585:
580:
569:
565:
561:
557:
553:
549:
545:
541:
537:
533:
532:
529:
525:
520:
517:
507:
503:
499:
495:
491:
487:
483:
479:
475:
471:
470:
467:
463:
458:
455:
454:
451:
449:
445:
443:
442:
438:
437:
434:
432:
428:
424:
420:
416:
408:
403:
399:
395:
390:
380:
376:
369:
362:
356:
349:
341:
337:
333:
328:
324:
319:
315:
307:
302:
298:
294:
289:
279:
275:
268:
261:
255:
248:
244:
238:
234:
230:
225:
221:
216:
212:
208:
204:
200:
196:
192:
188:
184:
180:
176:
172:
164:
159:
152:
147:
142:
131:
129:
125:
121:
117:
113:
109:
105:
101:
97:
93:
89:
83:
78:
75:
74:
70:
67:
60:
56:
51:
47:
43:
38:
33:
28:
24:
19:
5538:
5517:
5485:
5455:Pateclizumab
5451:
5436:
5402:
5362:
5341:
5320:
5298:
5284:Antagonists:
5283:
5263:
5241:
5211:
5185:
5166:Antagonists:
5165:
5119:CXCL1 (MGSA)
5115:
5085:
5076:Antagonists:
5075:
5055:
5014:Bertilimumab
5010:
4981:
4955:
4934:
4908:
4882:
4861:
4840:
4810:
4765:
4743:
4718:
4657:
4636:
4614:
4611:
4574:CCL9 (CCL10)
4555:
4452:
4431:
4400:
4392:By function/
4103:IL28/IFNL2+3
3451:
3368:
3353:
3338:
3323:
3308:
3293:
3213:
3209:
3176:
3172:
3137:
3116:
3110:
3068:
3064:
3057:
3024:
3020:
3013:
2986:
2982:
2972:
2927:
2923:
2913:
2889:10.3275/7981
2883:(6): 585–9.
2880:
2874:
2868:
2833:
2829:
2819:
2784:
2780:
2770:
2735:
2731:
2721:
2688:
2684:
2677:
2644:
2640:
2634:
2597:
2593:
2583:
2550:
2546:
2540:
2505:
2501:
2491:
2458:
2454:
2448:
2415:
2411:
2404:
2369:
2365:
2355:
2320:
2316:
2306:
2271:
2267:
2257:
2230:
2226:
2216:
2186:(4): 611–9.
2183:
2179:
2173:
2138:
2134:
2124:
2089:
2085:
2075:
2042:
2038:
2031:
2006:
2002:
1992:
1949:
1946:FEBS Letters
1945:
1935:
1913:(1): 200–3.
1910:
1906:
1900:
1867:
1863:
1856:
1811:
1807:
1797:
1754:
1750:
1740:
1731:
1722:
1713:
1704:
1606:
1595:
1580:
1549:
1545:
1530:
1523:
1504:
1495:
1464:
1452:
1442:
1411:
1402:
1373:human genome
1370:
1357:inflammation
1341:CC chemokine
1332:
1328:
1324:
1322:
1245:
1224:
1198:
1177:
1153:
1134:
1108:
1089:
1063:
1044:
1024:
1019:
860:MAPK cascade
750:angiogenesis
554:aortic valve
538:right kidney
446:
439:
166:External IDs
85:
18:
5547:Resolvin E1
5452:Antibodies:
5386:RTI-5152-12
5302:Ulocuplumab
5299:Antibodies:
5287:Mavorixafor
5242:Antibodies:
5220:CXCL9 (MIG)
5215:CXCL4 (PF4)
5154:Garnocestim
5011:Antibodies:
4841:Antibodies:
4744:Antibodies:
4320:IL17 family
4061:IL10 family
3980:IL12 family
3832:(grouped by
3820:Interleukin
3743:Lymphotoxin
3276:PDB gallery
2039:Circulation
1539:(EAE), and
1533:glial cells
1483:cathepsin K
1471:osteoblasts
1467:osteoclasts
1434:macrophages
1414:polypeptide
1393:amino acids
1387:. The CCL2
1331:(MCP1) and
476:gallbladder
405:81,994,226
392:81,992,671
304:34,257,208
291:34,255,274
144:Identifiers
5566:Categories
5366:Conolidine
4834:Vicriviroc
4824:INCB009471
4531:modulators
4427:Lymphokine
4265:IL1B/IL1F2
4260:IL1A/IL1F1
4256:IL1 family
4120:Interferon
4108:IL29/IFNL1
2227:Immunology
1699:, May 2017
1678:, May 2017
1655:References
1586:adipokines
1582:Adipocytes
805:chemotaxis
450:(ortholog)
187:HomoloGene
5577:Cytokines
5539:Agonists:
5518:Agonists:
5486:Agonists:
5437:Agonists:
5363:Agonists:
5342:Agonists:
5321:Agonists:
5277:Ubiquitin
5264:Agonists:
5245:Eldelumab
5212:Agonists:
5189:Ladarixin
5179:Navarixin
5174:Elubrixin
5169:Danirixin
5149:Emoctakin
5116:Agonists:
5089:Ladarixin
5079:Navarixin
5064:Emoctakin
5056:Agonists:
5004:Ungrouped
4982:Agonists:
4956:Agonists:
4935:Agonists:
4909:Agonists:
4883:Agonists:
4862:Agonists:
4829:Maraviroc
4814:Aplaviroc
4766:Agonists:
4719:Agonists:
4658:Agonists:
4612:Agonists:
4556:Agonists:
4305:33/IL1F11
4270:1Ra/IL1F3
3917:IL6 like/
3634:CXCL8/IL8
3432:Chemokine
3424:By family
3417:cytokines
1649:melatonin
1511:psoriasis
1507:monocytic
1487:autocrine
1430:monocytes
1416:, with a
1361:infection
1345:monocytes
1248:NP_035461
1227:NP_002973
1201:NM_011331
1180:NM_002982
1010:Orthologs
488:beta cell
472:vena cava
195:GeneCards
5542:Chemerin
5396:VUF15485
5235:Iroplact
5107:(IL-8Rβ)
5047:(IL-8Rα)
5020:Carlumab
4422:Monokine
3951:+non IL
3836:subunit)
3834:receptor
3805:TNFSF13B
3753:TNFC/LTB
3748:TNFB/LTA
3238:33827660
3230:17495598
3201:41684404
3193:10985244
3093:42491323
3085:20817086
3041:21900689
3005:16439461
2964:21589925
2924:PLOS ONE
2905:14613351
2897:21975431
2860:20029451
2811:13552110
2762:20205643
2713:45538922
2661:20542576
2626:20034406
2575:28336866
2567:11175802
2483:45028620
2475:19441905
2440:22254007
2432:16025454
2396:22756184
2388:15722361
2347:25944573
2339:18660381
2208:24366011
2200:17160712
2165:29375123
2108:17917677
2067:12320863
2059:16116069
2037:Study".
1907:Genomics
1892:24481789
1789:34988399
1751:iScience
1695:–
1674:–
1627:, CCL2,
1591:myocytes
1462:MMP-12.
1383:and two
1367:Genomics
1337:cytokine
1296:Wikidata
989:Sources:
4844:PRO-140
4310:18/IL1G
4052:Type II
3984:IL12RB1
3890:β chain
3844:γ chain
3800:TNFSF13
3795:TNFSF11
3790:TNFSF10
3472:/RANTES
3164:1661560
3049:9801961
2955:3092759
2932:Bibcode
2851:2949175
2803:8472896
2753:3684802
2705:7860708
2669:5121343
2617:2804573
2532:9104823
2523:2196251
2298:1569397
2289:2119199
2249:8550082
2240:1383948
2156:6052833
2116:8242432
2023:2923622
1984:7097272
1976:2465924
1954:Bibcode
1927:2004761
1884:8830793
1848:8170963
1816:Bibcode
1780:8693412
1759:Bibcode
1697:Ensembl
1676:Ensembl
1385:introns
1371:In the
1122:UniProt
1077:Ensembl
1016:Species
995:QuickGO
425:pattern
151:Aliases
5531:CMKLR1
5502:Others
5478:CX3CR1
5420:C (XC)
5381:LIH383
5376:CCX771
5345:CXCL16
5324:CXCL13
4300:IL1F10
4197:IFNA21
4192:IFNA17
4187:IFNA16
4182:IFNA14
4177:IFNA13
4172:IFNA10
3829:Type I
3785:TNFSF9
3780:TNFSF8
3775:TNFSF7
3770:TNFSF6
3760:TNFSF4
3695:CX3CL1
3679:CXCL17
3674:CXCL16
3669:CXCL15
3664:CXCL14
3659:CXCL13
3654:CXCL12
3649:CXCL11
3644:CXCL10
3466:/MIP1β
3460:/MIP1α
3236:
3228:
3199:
3191:
3162:
3152:
3108:Human
3091:
3083:
3047:
3039:
3003:
2962:
2952:
2903:
2895:
2858:
2848:
2809:
2801:
2760:
2750:
2711:
2703:
2667:
2659:
2624:
2614:
2600:: 40.
2573:
2565:
2530:
2520:
2481:
2473:
2438:
2430:
2394:
2386:
2345:
2337:
2296:
2286:
2247:
2237:
2206:
2198:
2163:
2153:
2114:
2106:
2065:
2057:
2021:
1982:
1974:
1925:
1890:
1882:
1846:
1836:
1787:
1777:
1633:NF-κB2
1629:NF-κB1
1615:, HO (
1552:amylin
1475:RANTES
1351:, and
1282:search
1280:PubMed
1155:Q62401
1136:P13500
1032:Entrez
596:BioGPS
562:dermis
546:thymus
542:embryo
534:cervix
492:rectum
183:108224
175:158105
5510:CCBP2
5403:PAMs:
5355:CXCR7
5334:CXCR6
5313:CXCR5
5256:CXCR4
5204:CXCR3
5186:NAMs:
5144:CXCL7
5139:CXCL6
5134:CXCL5
5129:CXCL3
5124:CXCL2
5104:CXCR2
5086:NAMs:
5059:CXCL6
5044:CXCR1
4995:CCL25
4990:CCL21
4985:CCL19
4974:CCR11
4964:CCL28
4959:CCL27
4948:CCR10
4938:CCL25
4917:CCL16
4891:CCL21
4886:CCL19
4865:CCL20
4811:NAMs:
4804:CCL16
4799:CCL14
4794:CCL13
4789:CCL11
4737:CCL22
4732:CCL17
4701:CCL28
4696:CCL26
4691:CCL24
4686:CCL18
4681:CCL15
4676:CCL13
4671:CCL11
4637:NAMs:
4630:CCL16
4625:CCL12
4594:CCL23
4589:CCL16
4584:CCL15
4579:CCL14
4362:KITLG
4350:Other
4336:IL17A
4295:IL1F9
4290:IL1F8
4285:IL1F7
4280:IL1F6
4275:IL1F5
4212:IFNW1
4202:IFNB1
4167:IFNA8
4162:IFNA7
4157:IFNA6
4152:IFNA5
4147:IFNA4
4142:IFNA2
4137:IFNA1
4016:Other
3919:gp130
3908:GMCSF
3688:CX3CL
3639:CXCL9
3629:CXCL7
3624:CXCL6
3619:CXCL5
3614:CXCL4
3609:CXCL3
3604:CXCL2
3598:CXCL1
3582:CCL28
3577:CCL27
3572:CCL26
3567:CCL25
3562:CCL24
3557:CCL23
3552:CCL22
3547:CCL21
3542:CCL20
3537:CCL19
3531:CCL18
3526:CCL17
3521:CCL16
3516:CCL15
3511:CCL14
3506:CCL13
3501:CCL12
3496:CCL11
3454:/MCP1
3234:S2CID
3197:S2CID
3089:S2CID
3045:S2CID
2901:S2CID
2807:S2CID
2709:S2CID
2665:S2CID
2571:S2CID
2479:S2CID
2436:S2CID
2392:S2CID
2343:S2CID
2317:Blood
2204:S2CID
2112:S2CID
2063:S2CID
1980:S2CID
1888:S2CID
1839:43639
1645:IL-10
1641:IL-1β
1637:TNF-α
1613:IL-1β
1609:TNF-α
1572:NF-κB
1381:exons
1065:20293
1025:Mouse
1020:Human
991:Amigo
448:Mouse
441:Human
388:Start
323:Mouse
287:Start
283:17q12
220:Human
5469:CX3C
5429:XCR1
4927:CCR9
4912:CCL1
4901:CCR8
4875:CCR7
4854:CCR6
4784:CCL8
4758:CCR5
4711:CCR4
4666:CCL7
4650:CCR3
4620:CCL8
4615:CCL2
4604:CCR2
4569:CCL6
4548:CCR1
4482:IL13
4477:IL10
4446:TNFβ
4441:IFNγ
4413:TNFA
4394:cell
4374:SPP1
4332:IL25
4328:IL17
4230:IFNG
4207:IFNK
4093:IL26
4088:IL24
4083:IL20
4078:IL19
4073:IL22
4069:IL10
4038:IL34
4033:IL32
4028:IL16
4023:IL14
4007:IL35
4002:IL27
3997:IL23
3992:IL12
3968:CTF1
3963:CNTF
3947:IL31
3942:IL30
3937:IL27
3932:IL11
3880:IL21
3865:IL13
3856:IL15
3738:TNFA
3716:XCL2
3711:XCL1
3591:CXCL
3491:CCL9
3486:CCL8
3481:CCL7
3476:CCL6
3470:CCL5
3464:CCL4
3458:CCL3
3452:CCL2
3447:CCL1
3369:2bdn
3354:1ml0
3339:1don
3324:1dom
3309:1dol
3294:1dok
3226:PMID
3189:PMID
3160:PMID
3150:ISBN
3117:CCL2
3111:CCL2
3081:PMID
3037:PMID
3001:PMID
2960:PMID
2893:PMID
2856:PMID
2799:PMID
2758:PMID
2701:PMID
2657:PMID
2622:PMID
2563:PMID
2528:PMID
2471:PMID
2428:PMID
2384:PMID
2335:PMID
2294:PMID
2245:PMID
2196:PMID
2161:PMID
2104:PMID
2055:PMID
2019:PMID
1972:PMID
1923:PMID
1880:PMID
1844:PMID
1785:PMID
1625:iNOS
1621:HO-2
1619:and
1617:HO-1
1576:CCR2
1570:and
1560:ERK2
1556:ERK1
1517:and
1469:and
1456:CCR2
1448:CCR4
1446:and
1444:CCR2
1436:and
1323:The
1046:6347
431:Bgee
379:Band
340:Chr.
278:Band
237:Chr.
199:CCL2
191:2245
171:OMIM
158:CCL2
128:4ZK9
124:4R8I
120:3IFD
116:4DN4
112:2NZ1
108:2BDN
104:1ML0
100:1DON
96:1DOM
92:1DOL
88:1DOK
69:RCSB
66:PDBe
35:CCL2
5267:MIF
5035:CXC
4472:IL6
4467:IL5
4462:IL4
4408:IL1
4379:MIF
3958:LIF
3953:OSM
3927:IL6
3903:IL5
3898:IL3
3875:IL9
3870:IL7
3861:IL4
3852:IL2
3810:EDA
3730:TNF
3704:XCL
3600:/KC
3440:CCL
3218:doi
3181:doi
3142:doi
3073:doi
3029:doi
3025:302
2991:doi
2987:147
2950:PMC
2940:doi
2885:doi
2846:PMC
2838:doi
2789:doi
2748:PMC
2740:doi
2693:doi
2649:doi
2645:224
2612:PMC
2602:doi
2555:doi
2518:PMC
2510:doi
2506:185
2463:doi
2420:doi
2416:489
2374:doi
2370:280
2325:doi
2321:112
2284:PMC
2276:doi
2272:175
2235:PMC
2188:doi
2151:PMC
2143:doi
2094:doi
2047:doi
2043:112
2011:doi
2007:159
1962:doi
1950:244
1915:doi
1872:doi
1834:PMC
1824:doi
1775:PMC
1767:doi
1623:),
1602:BNP
1568:AP1
1564:JNK
401:End
300:End
203:OMA
179:MGI
59:PDB
5568::
4539:CC
4258::
4222:II
3415::
3232:.
3224:.
3214:18
3212:.
3195:.
3187:.
3177:68
3175:.
3158:.
3148:.
3087:.
3079:.
3069:45
3067:.
3043:.
3035:.
3023:.
2999:.
2985:.
2981:.
2958:.
2948:.
2938:.
2926:.
2922:.
2899:.
2891:.
2881:35
2879:.
2854:.
2844:.
2834:30
2832:.
2828:.
2805:.
2797:.
2783:.
2779:.
2756:.
2746:.
2734:.
2730:.
2707:.
2699:.
2689:56
2687:.
2663:.
2655:.
2643:.
2620:.
2610:.
2596:.
2592:.
2569:.
2561:.
2549:.
2526:.
2516:.
2504:.
2500:.
2477:.
2469:.
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