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Chloroprene

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In addition, chloroprene has a high reactivity and should be stored away from oxidizing agents such as perchlorate, peroxides, permanganates, chlorates, nitrates, chlorine, bromine, and fluorine. All activities inducing a potential fire hazard should be avoided. For instance, smoking, having open flames or using sparking tools to open or close storage containers should be prohibited. It is also advised that grounded and bonded metal containers are used for the transport of chloroprene.
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designated chloroprene as likely to be carcinogenic to humans based on evidence from studies that showed a statistically significant association between occupational chloroprene exposure and the risk of lung cancer. As early as 1975, NIOSH had identified the potential health hazards of chloroprene in
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The high vaporization potential and flammability of chloroprene has significant implications for handling and storage operations in the occupational setting. Chloroprene should be stored in closed containers in a cool, well-ventilated area with the temperature no higher than 50 °F (10 °C).
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with support from human data that are accepted as adequate in quality but may not be enough to declare an A1 (known human carcinogen) designation. Additionally, the TLV basis for these designations are due to scientific studies that show an association between chloroprene exposure and lung cancer,
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The primary occupational concern for chloroprene is limited to the facilities producing chloroprene and using chloroprene to produce the synthetic rubber, polychloroprene. NIOSH developed a list of actions to address specific workplace hazards. These actions are represented in their diagram of the
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Several epidemiological studies and toxicological reports provide evidence of chloroprene's capability to inflict occupational health and safety concerns. However, varying reviews of the degree to which chloroprene should be held responsible for health concerns highlight the criticality of sound
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Manfred Rossberg, Wilhelm Lendle, Gerhard Pfleiderer, Adolf Tögel, Eberhard-Ludwig Dreher, Ernst Langer, Heinz Rassaerts, Peter Kleinschmidt, Heinz Strack, Richard Cook, Uwe Beck, Karl-August Lipper, Theodore R. Torkelson, Eckhard Löser, Klaus K. Beutel, "Chlorinated Hydrocarbons" in Ullmann's
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Chloroprene is classified as a polytropic poison, and it causes organic disturbances in the nervous system and cardiovascular system. Examinations of the cardiovascular system show muffled heart sounds, reduced arterial pressure, and tachycardia. Within exposed workers, they report respiratory
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that apply to chloroprene. From left: flammability; carcinogenicity, mutagenicity, reproductive toxicity, respiratory sensitization, target organ toxicity, or aspiration toxicity; irritant (skin and eye), skin sensitizer, respiratory tract irritant, hazardous to ozone layer, may have narcotic
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in the 3 position and the chlorine atom in the 4 position thereby forming a double bond between carbons 3 and 4. In 1983, approximately 2,000,000 kg was produced in this manner. The chief impurity in chloroprene prepared in this way is 1-chlorobuta-1,3-diene, which is usually separated by
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adds to 1,3-butadiene to afford a mixture of 3,4-dichlorobut-1-ene and 1,4-dichlorobut-2-ene. The 1,4-dichloro isomer is subsequently isomerized to 3,4 isomer, which in turn is treated with base to induce dehydrochlorination to 2-chlorobuta-1,3-diene. This dehydrohalogenation entails loss of a
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In 2022, a request made by Denka to regulate chloroprene emissions was rejected by EPA. The request establishes a revision of EPA’s 2010 assessment of the chemical, arguing that the model used to estimate human cancer risk based on experiments, performed on mice, was not rigorous.
1690:, chloroprene was designated with a skin and an A2 notation. The skin notation designation is based on animal and human research that have shown chloroprene's ability to be absorbed by the skin. An A2 designation by the ACGIH means that the substance is a suspected human 1451:'s rating system, chloroprene is designated with a category 2 health hazard (temporary incapacitation or residual injury), a category 3 fire hazard (ignition under the presence of moderate heat), and a category 1 reactivity (unstable at high temperatures and pressures). 1715:
The only known environmental effect is related to how chloroprene is volatile and spreads rapidly through the air. This highly flammable component increases the possibility of causing a fire or explosion releasing irritating or toxic fumes (or gases).
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Chloroprene is toxic. It is reactive towards air, producing peroxides, which are also toxic. Handling of and exposure to chloroprene poses an occupational health risk to workers involved in the manufacture and production of neoprene.
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Chloroprene, if inhaled in any amount over 1ppm is toxic to the human body. Chloroprene is carcinogenic, can cause temporary hair loss on the exposed area, and can cause damage to the eyes and skin.
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Carothers, Wallace H.; Williams, Ira.; Collins, Arnold M.; Kirby, James E. (November 1931). "Acetylene Polymers and their Derivatives. II. A New Synthetic Rubber: Chloroprene and its Polymers".
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This process is energy-intensive and has high investment costs. Furthermore, the intermediate vinyl acetylene is unstable. This "acetylene process" has been replaced by a process which adds
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Although it may have been discovered earlier, chloroprene was largely developed by DuPont during the early 1930s, specifically with the formation of neoprene in mind. The chemists
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Chronic exposure to chloroprene may have the following symptoms: liver function abnormalities, disorders of the cardiovascular system, and depression of the immune system.
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scientific research. Only one fatality as a result of chloroprene intoxication has been recorded which was a result of cleaning a container used for chloroprene.
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has designated the following hazards for exposure to chloroprene: flammable, toxic, dangerous to the environment, health hazard and irritant. Chloroprene poses
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2018 TLVs and BEIs: Based on the Documentation of the Threshold Limit Values for Chemical Substances and Physical Agents & Biological Exposure Indices
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U.S. EPA. IRIS Toxicological Review of Chloroprene (Final Report). U.S. Environmental Protection Agency, Washington, DC, EPA/635/R-09/010F, 2010.
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The fate of chloroprene in the environment has been examined. Due to its volatility and extreme reactivity, it is not expected to bioaccumulate.
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Rickert, Annette; Hartung, Benno; Kardel, Bernd; Teloh, Johanna; Daldrup, Thomas (2012-02-10). "A fatal intoxication by chloroprene".
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Until the 1960s, chloroprene production was dominated by the "acetylene process," which was modeled after the original synthesis of
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their bulletin primarily citing two Russian cohort studies from those working with chloroprene in an occupational setting.
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are generally accredited with its development and commercialisation although the work was based upon that of
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Smith, John K. (January 1985). "The Ten-Year Invention: Neoprene and Du Pont Research, 1930-1939".
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As a way to visually communicate hazards associated with chloroprene exposure, the United Nations
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Lynch, Jeremiah (2001-06-01). "Occupational exposure to butadiene, isoprene and chloroprene".
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National Institute of Environmental Health Sciences. National Toxicology Program (2016).
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Safety and Health Topics | Fire Safety | Occupational Safety and Health Administration
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to afford 4-chloro-1,2-butadiene (an allene derivative), which in the presence of
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problems, eye and skin irritation, chest pains, and neurological symptoms.
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Chloroprene is a colorless volatile liquid, almost exclusively used as a
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Globally Harmonized System of Classification and Labeling of Chemicals
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Encyclopedia of Industrial Chemistry, 2006 John Wiley-VCH: Weinheim.
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Except where otherwise noted, data are given for materials in their
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Chloroprene, 2-chloro-1,3-butadiene, Chlorobutadiene, β-Chloroprene
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is dimerized to give vinyl acetylene, which is then combined with
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effects; aquatic toxicity; and acute toxicity (fatal or toxic).
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House Committee on Science, Space, and Technology Republicans
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Immediately Dangerous to Life or Health Concentrations (IDLH)
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Only stabilized chloroprene can be transported in U.S..
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https://nj.gov/health/eoh/rtkweb/documents/fs/0407.pdf
1133:) is a chemical compound with the molecular formula CH 2456:
National Institute for Occupational Safety and Health
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National Institute for Occupational Safety and Health
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National Institute for Occupational Safety and Health
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New Jersey Department of Health and Senior Services
2032:"Chloroprene, Stabilized | Cameo Chemicals | NOAA" 1930:U.S. Occupational Safety and Health Administration 1906:U.S. Occupational Safety and Health Administration 1695:upper respiratory tract (URT) and eye irritation. 675: 2503: 1193:Chloroprene is produced in three steps from 1,3- 687: 282: 2488:LaPlace, St. John the Baptist Parish, Louisiana 2070:"Current intelligence bulletin 1 - chloroprene" 1497: 1348:Occupational health and safety, and regulations 868: 92: 841: 695: 1985:Occupational Safety and Health Administration 1605:Iceland OEL Short Term Exposure Limit (STEL) 1512:Occupational exposure limits for chloroprene 1731: 511:59.4 °C (138.9 °F; 332.5 K) 2246:Centers for Disease Control and Prevention 2074:Centers for Disease Control and Prevention 911:−15.6 °C (3.9 °F; 257.5 K) 813: 361: 210: 188: 2350:Report on Carcinogens, fourteenth edition 2332: 2298: 318: 2450:NIOSH Pocket Guide to Chemical Hazards. 1833:Journal of the American Chemical Society 1826: 1824: 1762:NIOSH Pocket Guide to Chemical Hazards. 1473: 501:−130 °C (−202 °F; 143 K) 2445:International Chemical Safety Card 0133 357: 2504: 2404: 1806: 1804: 1802: 1779: 1777: 1757: 1755: 1753: 1751: 1749: 1549:Mine Safety and Health Administration 201: 2264: 2236: 2234: 2169: 2167: 2123: 2055: 2053: 2051: 1857: 1821: 389:Key: YACLQRRMGMJLJV-UHFFFAOYSA-N 168: 148: 1947: 1945: 1449:National Fire Protection Association 1224: 386:InChI=1S/C4H5Cl/c1-3-4(2)5/h3H,1-2H2 1951: 1799: 1774: 1746: 399:Key: YACLQRRMGMJLJV-UHFFFAOYAQ 396:InChI=1/C4H5Cl/c1-3-4(2)5/h3H,1-2H2 273: 257: 13: 2341: 2280: 2231: 2210: 2164: 2048: 1698: 1573:Denmark OEL ceiling concentration 1465: 864: 608:Highly flammable, irritant, toxic 36: 26: 14: 2548: 2438: 2305:Environmental Health Perspectives 1942: 1902:"Hazard Communication Pictograms" 1723: 1149:polychloroprene, better known as 2218:"Hazardous Substance Fact Sheet" 1416: 1407: 1398: 1389: 1380: 1249: 1088: 641: 636: 631: 2423: 2398: 2374: 2299:Sanotskii, I V (October 1976). 2292: 2258: 2188:10.1016/j.forsciint.2011.03.029 2126:Chemico-Biological Interactions 2117: 2088: 2062: 2024: 1997: 1459:Environmental Protection Agency 1185:, with whom they collaborated. 1084:(at 25 °C , 100 kPa). 2176:Forensic Science International 1970: 1918: 1894: 1851: 1707: 595:Occupational safety and health 1: 2405:Lerner, Sharon (2022-03-17). 2142:10.1016/S0009-2797(01)00191-0 1817:10.1002/14356007.a06_233.pub2 1739: 1188: 995:(US health exposure limits): 1677:The Netherlands OEL MAC-TGG 1504:occupational exposure limits 1498:Occupational exposure limits 7: 929:or concentration (LD, LC): 459:88.5365 g/mol 22: 10: 2553: 1367: 1356:3 (flammable liquid). Its 1205:of 3,4-dichlorobut-1-ene. 1160: 1145:for the production of the 2532:IARC Group 2B carcinogens 1732:Effects on the human body 1669:Switzerland OEL MAK-week 1511: 1078: 1038: 989: 925: 612: 592: 587: 428: 408: 373: 76: 68: 56: 51: 21: 2527:Hazardous air pollutants 2265:Lowry, Larry K. (2004). 1958:pubchem.ncbi.nlm.nih.gov 1688:2018 TLV and BEI booklet 983:1052 ppm (rabbit, 8 hr) 708:Precautionary statements 2082:10.26616/NIOSHPUB781271 2036:cameochemicals.noaa.gov 1183:Julius Arthur Nieuwland 1021:Ca C 1 ppm (3.6 mg/m) 1860:Technology and Culture 1482: 1131:2-chlorobuta-1,3-diene 1008:TWA 25 ppm (90 mg/m) 947:450 mg/kg (rat, oral) 875: 62:2-Chlorobuta-1,3-diene 42: 32: 1533:ACGIH TLV 8-hour TWA 1488:Hierarchy of Controls 1480:Hierarchy of Controls 1477: 1427:GHS hazard pictograms 1270:1,4-dichloro-2-butene 1073:2,3-Dichlorobutadiene 965:3207 ppm (rat, 4 hr) 874: 40: 30: 2242:"Template Package 4" 2128:. 135–136: 207–214. 2012:www.fm.colostate.edu 1629:New Zealand OEL TWA 1557:Austria OEL MAK-TMW 1541:OSHA PEL 8-hour TWA 985:350 ppm (cat, 8 hr) 959:median concentration 857:(fire diamond) 58:Preferred IUPAC name 2386:www.greenspec.co.uk 2134:2001CBI...135..207L 1978:"Flammable liquids" 1845:10.1021/ja01362a042 1653:Poland OEL MAC TWA 1274:dehydrochlorination 1233:. In this process, 1203:dehydrochlorination 518:Solubility in water 130:Beilstein Reference 18: 2481:2018-11-27 at the 2317:10.1289/ehp.761785 1483: 1360:is 1991 and is in 1352:Chloroprene is in 1243:copper(I) chloride 1111:Infobox references 1039:Related compounds 1030:(Immediate danger) 876: 43: 33: 16: 2512:Conjugated dienes 2359:978-1-5231-0852-7 1839:(11): 4203–4225. 1684: 1683: 1447:According to the 1239:hydrogen chloride 1225:Acetylene process 1171:Wallace Carothers 1119:Chemical compound 1117: 1116: 1064:Related compounds 666:Hazard statements 563:188 mmHg (20 °C) 467:Colorless liquid 342:CompTox Dashboard 118:Interactive image 47: 46: 2544: 2537:Chemical hazards 2459: 2432: 2427: 2421: 2420: 2418: 2417: 2402: 2396: 2395: 2393: 2392: 2378: 2372: 2371: 2345: 2339: 2338: 2336: 2296: 2290: 2284: 2278: 2277: 2271: 2262: 2256: 2255: 2253: 2252: 2238: 2229: 2228: 2222: 2214: 2208: 2207: 2182:(1–3): 110–113. 2171: 2162: 2161: 2121: 2115: 2114: 2100: 2092: 2086: 2085: 2066: 2060: 2057: 2046: 2045: 2043: 2042: 2028: 2022: 2021: 2019: 2018: 2009: 2001: 1995: 1994: 1992: 1991: 1982: 1974: 1968: 1967: 1965: 1964: 1949: 1940: 1939: 1937: 1936: 1922: 1916: 1915: 1913: 1912: 1898: 1892: 1891: 1855: 1849: 1848: 1828: 1819: 1808: 1797: 1796: 1781: 1772: 1771: 1759: 1597:Hungary OEL TWA 1581:Finland OEL TWA 1565:Belgium OEL TWA 1509: 1508: 1420: 1411: 1402: 1393: 1384: 1343: 1322: 1302: 1253: 1155:synthetic rubber 1101: 1095: 1092: 1091: 977:lowest published 917:Explosive limits 896: 889: 882: 867: 847: 843: 839: 835: 831: 827: 823: 819: 815: 811: 807: 803: 799: 795: 791: 787: 783: 779: 775: 771: 767: 763: 759: 755: 751: 747: 743: 739: 735: 731: 727: 723: 719: 715: 701: 697: 693: 689: 685: 681: 677: 673: 645: 640: 635: 570:Refractive index 436:Chemical formula 366: 365: 350: 348: 322: 286: 275: 261: 239:Gmelin Reference 222: 214: 203: 192: 172: 152: 120: 96: 23: 19: 15: 2552: 2551: 2547: 2546: 2545: 2543: 2542: 2541: 2522:Organochlorides 2502: 2501: 2483:Wayback Machine 2441: 2436: 2435: 2428: 2424: 2415: 2413: 2403: 2399: 2390: 2388: 2380: 2379: 2375: 2360: 2346: 2342: 2297: 2293: 2285: 2281: 2269: 2263: 2259: 2250: 2248: 2240: 2239: 2232: 2220: 2216: 2215: 2211: 2172: 2165: 2122: 2118: 2098: 2094: 2093: 2089: 2068: 2067: 2063: 2058: 2049: 2040: 2038: 2030: 2029: 2025: 2016: 2014: 2007: 2003: 2002: 1998: 1989: 1987: 1980: 1976: 1975: 1971: 1962: 1960: 1950: 1943: 1934: 1932: 1924: 1923: 1919: 1910: 1908: 1900: 1899: 1895: 1872:10.2307/3104528 1856: 1852: 1829: 1822: 1809: 1800: 1785:"ß-Chloroprene" 1783: 1782: 1775: 1760: 1747: 1742: 1734: 1726: 1710: 1701: 1699:Chronic effects 1686:In the ACGIH's 1661:Sweden OEL TWA 1637:Norway OEL TWA 1621:Mexico OEL TWA 1589:France OEL VME 1500: 1468: 1466:Hazard controls 1434: 1433: 1432: 1431: 1423: 1422: 1421: 1413: 1412: 1404: 1403: 1395: 1394: 1386: 1385: 1370: 1350: 1341: 1337: 1333: 1329: 1325: 1321: 1317: 1313: 1309: 1305: 1300: 1296: 1292: 1288: 1284: 1280: 1262: 1227: 1191: 1167:Elmer K. Bolton 1163: 1140: 1136: 1120: 1113: 1108: 1107: 1106:  ?) 1097: 1093: 1089: 1085: 1071: 1065: 1055: 1049: 1031: 1018: 1005: 984: 980: 974: 962: 956: 944: 938: 901: 900: 899: 898: 891: 884: 877: 873: 865: 710: 668: 654: 628: 605: 580: 578: 541: 523:0.026 g/100 mL 520: 448: 444: 438: 424: 421: 416: 415: 404: 401: 400: 397: 391: 390: 387: 381: 380: 369: 351: 344: 325: 305: 289: 276: 264: 241: 232: 195: 175: 155: 132: 123: 110: 99: 86: 72: 64: 63: 12: 11: 5: 2550: 2540: 2539: 2534: 2529: 2524: 2519: 2514: 2500: 2499: 2495: 2490: 2485: 2474: 2470: 2460: 2447: 2440: 2439:External links 2437: 2434: 2433: 2422: 2397: 2373: 2358: 2340: 2291: 2289:. ACGIH, 2018. 2279: 2257: 2230: 2209: 2163: 2116: 2087: 2076:. 2018-10-16. 2061: 2047: 2023: 1996: 1969: 1941: 1917: 1893: 1850: 1820: 1798: 1773: 1744: 1743: 1741: 1738: 1733: 1730: 1725: 1724:Transportation 1722: 1709: 1706: 1700: 1697: 1682: 1681: 1678: 1674: 1673: 1670: 1666: 1665: 1662: 1658: 1657: 1654: 1650: 1649: 1646: 1642: 1641: 1638: 1634: 1633: 1630: 1626: 1625: 1622: 1618: 1617: 1614: 1613:Korea OEL TWA 1610: 1609: 1606: 1602: 1601: 1598: 1594: 1593: 1590: 1586: 1585: 1582: 1578: 1577: 1574: 1570: 1569: 1566: 1562: 1561: 1558: 1554: 1553: 1550: 1546: 1545: 1542: 1538: 1537: 1534: 1530: 1529: 1526: 1522: 1521: 1520:Concentration 1518: 1514: 1513: 1499: 1496: 1467: 1464: 1425: 1424: 1415: 1414: 1406: 1405: 1397: 1396: 1388: 1387: 1379: 1378: 1377: 1376: 1375: 1369: 1366: 1349: 1346: 1345: 1344: 1339: 1335: 1331: 1327: 1323: 1319: 1315: 1311: 1307: 1303: 1298: 1294: 1290: 1286: 1282: 1260: 1255: 1254: 1231:vinylacetylene 1226: 1223: 1190: 1187: 1175:Arnold Collins 1162: 1159: 1138: 1134: 1118: 1115: 1114: 1109: 1087: 1086: 1082:standard state 1079: 1076: 1075: 1069:Vinyl chloride 1066: 1063: 1060: 1059: 1050: 1044: 1041: 1040: 1036: 1035: 1032: 1026: 1023: 1022: 1019: 1013: 1010: 1009: 1006: 1000: 997: 996: 987: 986: 981: 972: 970: 967: 966: 963: 954: 952: 949: 948: 945: 936: 934: 931: 930: 923: 922: 919: 913: 912: 909: 903: 902: 892: 885: 878: 863: 862: 861: 860: 858: 849: 848: 794:P305+P351+P338 782:P303+P361+P353 711: 706: 703: 702: 669: 664: 661: 660: 655: 650: 647: 646: 629: 624: 621: 620: 610: 609: 606: 603: 600: 599: 590: 589: 585: 584: 581: 576: 568: 565: 564: 561: 559:Vapor pressure 555: 554: 531: 525: 524: 521: 516: 513: 512: 509: 503: 502: 499: 493: 492: 489: 483: 482: 475: 469: 468: 465: 461: 460: 457: 451: 450: 446: 442: 439: 434: 431: 430: 426: 425: 423: 422: 419: 411: 410: 409: 406: 405: 403: 402: 398: 395: 394: 392: 388: 385: 384: 376: 375: 374: 371: 370: 368: 367: 354: 352: 340: 337: 336: 333: 327: 326: 324: 323: 315: 313: 307: 306: 304: 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2083: 2079: 2075: 2071: 2065: 2056: 2054: 2052: 2037: 2033: 2027: 2013: 2006: 2000: 1986: 1979: 1973: 1959: 1955: 1954:"Chloroprene" 1948: 1946: 1931: 1927: 1921: 1907: 1903: 1897: 1889: 1885: 1881: 1877: 1873: 1869: 1865: 1861: 1854: 1846: 1842: 1838: 1834: 1827: 1825: 1818: 1814: 1807: 1805: 1803: 1794: 1790: 1786: 1780: 1778: 1769: 1765: 1758: 1756: 1754: 1752: 1750: 1745: 1737: 1729: 1721: 1717: 1713: 1705: 1696: 1693: 1689: 1679: 1676: 1675: 1671: 1668: 1667: 1663: 1660: 1659: 1655: 1652: 1651: 1647: 1645:Peru OEL TWA 1644: 1643: 1639: 1636: 1635: 1631: 1628: 1627: 1623: 1620: 1619: 1615: 1612: 1611: 1607: 1604: 1603: 1599: 1596: 1595: 1591: 1588: 1587: 1583: 1580: 1579: 1575: 1572: 1571: 1567: 1564: 1563: 1559: 1556: 1555: 1551: 1548: 1547: 1543: 1540: 1539: 1535: 1532: 1531: 1527: 1524: 1523: 1519: 1517:Organization 1516: 1515: 1510: 1507: 1505: 1495: 1491: 1489: 1481: 1476: 1472: 1463: 1460: 1455: 1452: 1450: 1445: 1443: 1439: 1428: 1419: 1410: 1401: 1392: 1383: 1374: 1365: 1363: 1362:packing group 1359: 1355: 1324: 1314:Cl → ClCH 1304: 1279: 1278: 1277: 1275: 1271: 1267: 1266:1,3-butadiene 1263: 1252: 1248: 1247: 1246: 1244: 1240: 1236: 1232: 1222: 1220: 1215: 1210: 1206: 1204: 1200: 1196: 1186: 1184: 1180: 1176: 1172: 1168: 1158: 1156: 1152: 1148: 1144: 1132: 1128: 1124: 1112: 1105: 1100: 1083: 1077: 1074: 1070: 1067: 1062: 1061: 1058: 1054: 1051: 1048: 1043: 1042: 1037: 1033: 1029: 1025: 1024: 1020: 1017:(Recommended) 1016: 1012: 1011: 1007: 1004:(Permissible) 1003: 999: 998: 994: 993: 988: 982: 978: 969: 968: 964: 960: 951: 950: 946: 942: 933: 932: 928: 924: 920: 918: 915: 914: 910: 908: 905: 904: 897: 890: 883: 859: 856: 855: 851: 850: 712: 709: 705: 704: 670: 667: 663: 662: 659: 656: 653: 649: 648: 644: 639: 634: 630: 627: 623: 622: 618: 616: 611: 607: 602: 601: 597: 596: 591: 586: 582: 575: 571: 567: 566: 562: 560: 557: 556: 553: 549: 545: 540: 539:diethyl ether 536: 532: 530: 527: 526: 522: 519: 515: 514: 510: 508: 507:Boiling point 505: 504: 500: 498: 497:Melting point 495: 494: 490: 488: 485: 484: 480: 476: 474: 471: 470: 466: 463: 462: 458: 456: 453: 452: 440: 437: 433: 432: 427: 418: 417: 414: 407: 393: 383: 382: 379: 372: 364: 360: 359:DTXSID5020316 356: 355: 353: 343: 339: 338: 334: 332: 329: 328: 321: 317: 316: 314: 312: 309: 308: 301: 300: 298: 296: 293: 292: 285: 281: 280: 278: 272: 268: 267: 260: 256: 255: 253: 251: 248: 247: 243: 240: 236: 235: 228: 227: 225: 223: 218: 217: 213: 209: 206: 204: 202:ECHA InfoCard 199: 198: 191: 187: 186: 184: 182: 179: 178: 171: 167: 166: 164: 162: 159: 158: 151: 147: 146: 144: 142: 139: 138: 134: 131: 127: 126: 119: 115: 114: 112: 108: 103: 102: 95: 91: 90: 88: 85: 81: 80: 75: 67: 59: 55: 50: 39: 35: 29: 25: 24: 20: 2467:Chloroprene. 2425: 2414:. Retrieved 2410: 2400: 2389:. Retrieved 2385: 2376: 2349: 2343: 2308: 2304: 2294: 2286: 2282: 2273: 2260: 2249:. Retrieved 2245: 2224: 2212: 2179: 2175: 2125: 2119: 2102: 2090: 2073: 2064: 2039:. Retrieved 2035: 2026: 2015:. Retrieved 2011: 1999: 1988:. Retrieved 1984: 1972: 1961:. Retrieved 1957: 1933:. Retrieved 1929: 1920: 1909:. Retrieved 1905: 1896: 1866:(1): 34–55. 1863: 1859: 1853: 1836: 1832: 1788: 1735: 1727: 1718: 1714: 1711: 1702: 1687: 1685: 1501: 1492: 1484: 1469: 1456: 1453: 1446: 1435: 1371: 1354:hazard class 1351: 1256: 1228: 1219:distillation 1207: 1199:chlorination 1192: 1179:Ira Williams 1164: 1153:, a type of 1130: 1122: 1121: 991: 926: 853: 657: 614: 604:Main hazards 593: 573: 542:Miscible in 491:0.9598 g/cm 295:RTECS number 170:ChEMBL555660 77:Identifiers 69:Other names 17:Chloroprene 2465:Monograph " 1708:Environment 1502:A table of 1442:fire hazard 1123:Chloroprene 941:median dose 927:Lethal dose 907:Flash point 652:Signal word 598:(OHS/OSH): 544:ethyl ether 533:Soluble in 464:Appearance 429:Properties 208:100.004.381 150:CHEBI:39481 41:Chloroprene 31:Chloroprene 2506:Categories 2416:2024-03-14 2391:2024-03-14 2251:2018-11-24 2041:2018-12-14 2017:2018-12-14 1990:2018-12-14 1963:2018-11-24 1935:2018-12-11 1911:2018-12-11 1740:References 1692:carcinogen 1525:NIOSH REL 1189:Production 1137:=CCl−CH=CH 921:1.9–11.3% 626:Pictograms 529:Solubility 455:Molar mass 420:C=C(Cl)C=C 320:42L93DWV3A 181:ChemSpider 105:3D model ( 84:CAS Number 2368:990561140 2325:0091-6765 2311:: 85–93. 2196:0379-0738 2150:0009-2797 1952:Pubchem. 1888:113234844 1656:0.55 ppm 1358:UN number 1338:=CClCH=CH 1330:CHClCH=CH 1318:CHClCH=CH 1268:, giving 1235:acetylene 1212:hydrogen 1195:butadiene 1053:Butadiene 838:P403+P235 834:P403+P233 830:P370+P378 822:P337+P313 818:P332+P313 798:P308+P313 790:P304+P340 786:P304+P312 778:P302+P352 774:P301+P312 617:labelling 477:Pungent, 449:Cl 331:UN number 302:EL9625000 229:204-818-0 221:EC Number 2517:Monomers 2479:Archived 2458:(NIOSH). 2204:21511420 2158:11397391 2111:33811055 1795:(NIOSH). 1770:(NIOSH). 1293:→ ClCH 1285:=CHCH=CH 1209:Chlorine 1151:neoprene 1057:Isoprene 1045:Related 1034:300 ppm 854:NFPA 704 588:Hazards 94:126-99-8 2452:"#0133" 2334:1475249 2130:Bibcode 1880:3104528 1764:"#0133" 1648:10 ppm 1632:10 ppm 1624:10 ppm 1616:10 ppm 1592:10 ppm 1568:10 ppm 1552:25 ppm 1544:25 ppm 1368:Hazards 1310:CH=CHCH 1297:CH=CHCH 1161:History 1147:polymer 1143:monomer 1104:what is 1102: ( 583:1.4583 552:benzene 548:acetone 535:alcohol 487:Density 271:PubChem 244:277888 135:741875 2366:  2356:  2331:  2323:  2202:  2194:  2156:  2148:  2109:  1886:  1878:  1680:5 ppm 1672:5 ppm 1664:1 ppm 1640:1 ppm 1608:1 ppm 1600:5 ppm 1584:1 ppm 1576:1 ppm 1560:5 ppm 1536:1 ppm 1528:1 ppm 1478:NIOSH 1342:+ HCl 1334:→ CH 1197:: (i) 1099:verify 1096:  1047:Dienes 658:Danger 481:-like 413:SMILES 259:C19208 161:ChEMBL 52:Names 2274:ACGIH 2270:(PDF) 2221:(PDF) 2107:S2CID 2099:(PDF) 2008:(PDF) 1981:(PDF) 1884:S2CID 1876:JSTOR 1289:+ Cl 1129:name 1127:IUPAC 992:NIOSH 479:ether 378:InChI 335:1991 284:31369 190:29102 141:ChEBI 107:JSmol 2463:IARC 2364:OCLC 2354:ISBN 2321:ISSN 2200:PMID 2192:ISSN 2154:PMID 2146:ISSN 1457:The 1326:ClCH 1306:ClCH 1264:to 1214:atom 1177:and 1028:IDLH 846:P501 842:P405 826:P362 814:P330 810:P321 806:P314 802:P312 770:P281 766:P280 762:P271 758:P270 754:P264 750:P261 746:P260 742:P243 738:P242 734:P241 730:P240 726:P233 722:P210 718:P202 714:P201 700:H373 696:H350 692:H335 688:H332 684:H319 680:H315 676:H302 672:H225 473:Odor 311:UNII 250:KEGG 2329:PMC 2313:doi 2184:doi 2180:215 2138:doi 2078:doi 1868:doi 1841:doi 1813:doi 1364:1. 1276::: 1015:REL 1002:PEL 615:GHS 347:EPA 274:CID 2508:: 2454:. 2409:. 2384:. 2362:. 2352:. 2327:. 2319:. 2309:17 2307:. 2303:. 2272:. 2244:. 2233:^ 2223:. 2198:. 2190:. 2178:. 2166:^ 2152:. 2144:. 2136:. 2105:. 2101:. 2072:. 2050:^ 2034:. 2010:. 1983:. 1956:. 1944:^ 1928:. 1904:. 1882:. 1874:. 1864:26 1862:. 1837:53 1835:. 1823:^ 1801:^ 1791:. 1787:. 1776:^ 1766:. 1748:^ 1301:Cl 1281:CH 1259:Cl 1221:. 1173:, 1169:, 1157:. 1139:2. 973:Lo 971:LC 955:50 953:LC 937:50 935:LD 844:, 840:, 836:, 832:, 828:, 824:, 820:, 816:, 812:, 808:, 804:, 800:, 796:, 792:, 788:, 784:, 780:, 776:, 772:, 768:, 764:, 760:, 756:, 752:, 748:, 744:, 740:, 736:, 732:, 728:, 724:, 720:, 716:, 698:, 694:, 690:, 686:, 682:, 678:, 674:, 619:: 550:, 546:, 537:, 2469:" 2419:. 2394:. 2370:. 2337:. 2315:: 2276:. 2254:. 2227:. 2206:. 2186:: 2160:. 2140:: 2132:: 2113:. 2084:. 2080:: 2044:. 2020:. 1993:. 1966:. 1938:. 1914:. 1890:. 1870:: 1847:. 1843:: 1815:: 1486:" 1340:2 1336:2 1332:2 1328:2 1320:2 1316:2 1312:2 1308:2 1299:2 1295:2 1291:2 1287:2 1283:2 1261:2 1135:2 1125:( 1094:N 979:) 975:( 961:) 957:( 943:) 939:( 895:0 888:3 881:2 579:) 577:D 574:n 572:( 447:5 445:H 443:4 441:C 349:) 345:( 109:)

Index

Chloroprene
Chloroprene
Preferred IUPAC name
CAS Number
126-99-8
JSmol
Interactive image
Beilstein Reference
ChEBI
CHEBI:39481
ChEMBL
ChEMBL555660
ChemSpider
29102
ECHA InfoCard
100.004.381
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EC Number
Gmelin Reference
KEGG
C19208
PubChem
31369
RTECS number
UNII
42L93DWV3A
UN number
CompTox Dashboard
DTXSID5020316
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