Knowledge

Cysteine—tRNA ligase

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1026: 263: 337: 179: 298: 428: 198: 609: 580: 454: 282: 493: 685: 191: 378:
Mccorquodale DJ (December 1964). "The separation and partial purification of aminoacyl-RNA synthetases from Escherichia coliI".
633: 1080: 142: 599: 1104: 421: 365: 361: 357: 745: 700: 705: 136: 695: 589: 118: 901: 712: 538: 414: 123: 248: 203: 111: 1016: 680: 675: 648: 558: 533: 518: 478: 1054: 46: 1073: 1002: 989: 976: 963: 950: 937: 924: 886: 670: 594: 553: 513: 503: 498: 483: 463: 896: 850: 793: 563: 473: 445: 270: 224: 139: 29: 63: 798: 543: 523: 508: 468: 308:, to be specific those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The 290: 660: 568: 548: 528: 380:
Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects
274: 1109: 819: 738: 690: 406: 1066: 891: 618: 99: 8: 855: 333: 286: 75: 41: 227: 34: 788: 349: 154: 1099: 395: 391: 353: 239: 130: 834: 829: 803: 731: 623: 387: 881: 865: 778: 309: 158: 1050: 1030: 919: 860: 665: 174: 1093: 824: 783: 149: 773: 399: 997: 932: 768: 294: 87: 278: 216: 971: 945: 235: 1025: 106: 1046: 984: 754: 628: 441: 437: 305: 231: 186: 82: 70: 58: 436: 958: 638: 653: 643: 94: 723: 1014: 251: 257: 352:have been solved for this class of enzymes, with 1091: 1074: 739: 422: 377: 1081: 1067: 746: 732: 429: 415: 326:cysteinyl-transfer ribonucleate synthetase 314:L-cysteine:tRNACys ligase (AMP-forming) 265:AMP + diphosphate + L-cysteinyl-tRNACys 1092: 727: 494:D-alanine—poly(phosphoribitol) ligase 410: 343: 304:This enzyme belongs to the family of 1040: 316:. Other names in common use include 258:{\displaystyle \rightleftharpoons } 13: 634:Von Hippel–Lindau tumor suppressor 14: 1121: 1024: 600:Long-chain-fatty-acid—CoA ligase 322:cysteinyl-transferRNA synthetase 332:. This enzyme participates in 696:Carbamoyl phosphate synthetase 590:Succinyl coenzyme A synthetase 252: 1: 371: 1053:. You can help Knowledge by 392:10.1016/0926-6550(64)90001-5 7: 753: 338:aminoacyl-trna biosynthesis 245:ATP + L-cysteine + tRNACys 10: 1126: 1105:Enzymes of known structure 1039: 681:Holocarboxylase synthetase 676:Argininosuccinate synthase 649:Anaphase-promoting complex 910: 902:Michaelis–Menten kinetics 874: 843: 812: 761: 713:Glutamate–cysteine ligase 671:Adenylosuccinate synthase 608: 579: 464:Aminoacyl tRNA synthetase 453: 318:cysteinyl-tRNA synthetase 197: 185: 173: 168: 164: 148: 129: 117: 105: 93: 81: 69: 57: 52: 40: 28: 23: 18: 794:Diffusion-limited enzyme 312:of this enzyme class is 661:Glutathione synthetase 259: 887:Eadie–Hofstee diagram 820:Allosteric regulation 691:Asparagine synthetase 595:Acetyl—CoA synthetase 299:L-cysteinyl-tRNA(Cys) 260: 897:Lineweaver–Burk plot 619:Glutamine synthetase 249: 221:cysteine—tRNA ligase 19:Cysteine—tRNA ligase 348:As of late 2007, 3 334:cysteine metabolism 273:of this enzyme are 856:Enzyme superfamily 789:Enzyme promiscuity 344:Structural studies 330:cysteine translase 255: 1062: 1061: 1012: 1011: 721: 720: 612:: Carbon-Nitrogen 240:chemical reaction 213: 212: 209: 208: 112:metabolic pathway 1117: 1083: 1076: 1069: 1041: 1029: 1028: 1020: 892:Hanes–Woolf plot 835:Enzyme activator 830:Enzyme inhibitor 804:Enzyme catalysis 748: 741: 734: 725: 724: 624:Ubiquitin ligase 431: 424: 417: 408: 407: 403: 356:accession codes 285:, whereas its 3 264: 262: 261: 256: 166: 165: 16: 15: 1125: 1124: 1120: 1119: 1118: 1116: 1115: 1114: 1090: 1089: 1088: 1087: 1037: 1035: 1023: 1015: 1013: 1008: 920:Oxidoreductases 906: 882:Enzyme kinetics 870: 866:List of enzymes 839: 808: 779:Catalytic triad 757: 752: 722: 717: 604: 583:: Carbon-Sulfur 575: 457:: Carbon-Oxygen 449: 440:: CO CS and CN 435: 374: 346: 310:systematic name 250: 247: 246: 12: 11: 5: 1123: 1113: 1112: 1107: 1102: 1086: 1085: 1078: 1071: 1063: 1060: 1059: 1034: 1033: 1010: 1009: 1007: 1006: 993: 980: 967: 954: 941: 928: 914: 912: 908: 907: 905: 904: 899: 894: 889: 884: 878: 876: 872: 871: 869: 868: 863: 858: 853: 847: 845: 844:Classification 841: 840: 838: 837: 832: 827: 822: 816: 814: 810: 809: 807: 806: 801: 796: 791: 786: 781: 776: 771: 765: 763: 759: 758: 751: 750: 743: 736: 728: 719: 718: 716: 715: 710: 709: 708: 703: 693: 688: 683: 678: 673: 668: 666:CTP synthetase 663: 658: 657: 656: 651: 646: 641: 636: 631: 621: 615: 613: 606: 605: 603: 602: 597: 592: 586: 584: 577: 576: 574: 573: 572: 571: 566: 561: 556: 551: 546: 541: 536: 531: 526: 521: 516: 511: 506: 501: 496: 491: 486: 481: 476: 471: 460: 458: 451: 450: 434: 433: 426: 419: 411: 405: 404: 373: 370: 345: 342: 267: 266: 254: 211: 210: 207: 206: 201: 195: 194: 189: 183: 182: 177: 171: 170: 162: 161: 152: 146: 145: 134: 127: 126: 121: 115: 114: 109: 103: 102: 97: 91: 90: 85: 79: 78: 73: 67: 66: 61: 55: 54: 50: 49: 44: 38: 37: 32: 26: 25: 21: 20: 9: 6: 4: 3: 2: 1122: 1111: 1108: 1106: 1103: 1101: 1098: 1097: 1095: 1084: 1079: 1077: 1072: 1070: 1065: 1064: 1058: 1056: 1052: 1049:article is a 1048: 1043: 1042: 1038: 1032: 1027: 1022: 1021: 1018: 1004: 1000: 999: 994: 991: 987: 986: 981: 978: 974: 973: 968: 965: 961: 960: 955: 952: 948: 947: 942: 939: 935: 934: 929: 926: 922: 921: 916: 915: 913: 909: 903: 900: 898: 895: 893: 890: 888: 885: 883: 880: 879: 877: 873: 867: 864: 862: 861:Enzyme family 859: 857: 854: 852: 849: 848: 846: 842: 836: 833: 831: 828: 826: 825:Cooperativity 823: 821: 818: 817: 815: 811: 805: 802: 800: 797: 795: 792: 790: 787: 785: 784:Oxyanion hole 782: 780: 777: 775: 772: 770: 767: 766: 764: 760: 756: 749: 744: 742: 737: 735: 730: 729: 726: 714: 711: 707: 704: 702: 699: 698: 697: 694: 692: 689: 687: 684: 682: 679: 677: 674: 672: 669: 667: 664: 662: 659: 655: 652: 650: 647: 645: 642: 640: 637: 635: 632: 630: 627: 626: 625: 622: 620: 617: 616: 614: 611: 607: 601: 598: 596: 593: 591: 588: 587: 585: 582: 578: 570: 567: 565: 562: 560: 557: 555: 552: 550: 547: 545: 542: 540: 539:Phenylalanine 537: 535: 532: 530: 527: 525: 522: 520: 517: 515: 512: 510: 507: 505: 502: 500: 497: 495: 492: 490: 487: 485: 482: 480: 477: 475: 472: 470: 467: 466: 465: 462: 461: 459: 456: 452: 447: 443: 439: 432: 427: 425: 420: 418: 413: 412: 409: 401: 397: 393: 389: 385: 381: 376: 375: 369: 367: 363: 359: 355: 351: 341: 339: 335: 331: 327: 323: 319: 315: 311: 307: 302: 300: 296: 292: 288: 284: 280: 276: 272: 244: 243: 242: 241: 237: 233: 229: 226: 222: 218: 205: 202: 200: 196: 193: 190: 188: 184: 181: 178: 176: 172: 167: 163: 160: 156: 153: 151: 150:Gene Ontology 147: 144: 141: 138: 135: 132: 128: 125: 122: 120: 116: 113: 110: 108: 104: 101: 98: 96: 92: 89: 88:NiceZyme view 86: 84: 80: 77: 74: 72: 68: 65: 62: 60: 56: 51: 48: 45: 43: 39: 36: 33: 31: 27: 22: 17: 1110:Ligase stubs 1055:expanding it 1044: 1036: 998:Translocases 995: 982: 969: 956: 943: 933:Transferases 930: 917: 774:Binding site 686:GMP synthase 488: 386:(4): 541–8. 383: 379: 347: 329: 325: 321: 317: 313: 303: 268: 220: 214: 76:BRENDA entry 769:Active site 295:diphosphate 64:IntEnz view 47:37318-56-2 24:Identifiers 1094:Categories 972:Isomerases 946:Hydrolases 813:Regulation 559:Tryptophan 534:Methionine 519:Isoleucine 479:Asparagine 372:References 350:structures 279:L-cysteine 271:substrates 217:enzymology 133:structures 100:KEGG entry 851:EC number 554:Threonine 514:Histidine 504:Glutamine 499:Glutamate 484:Aspartate 283:tRNA(Cys) 253:⇌ 236:catalyzes 53:Databases 1100:EC 6.1.1 875:Kinetics 799:Cofactor 762:Activity 564:Tyrosine 489:Cysteine 474:Arginine 448:6.1-6.3) 400:14262440 287:products 230:) is an 228:6.1.1.16 204:proteins 192:articles 180:articles 137:RCSB PDB 35:6.1.1.16 1031:Biology 985:Ligases 755:Enzymes 544:Proline 524:Leucine 509:Glycine 469:Alanine 442:ligases 438:Enzymes 306:ligases 159:QuickGO 124:profile 107:MetaCyc 42:CAS no. 1047:ligase 1017:Portal 959:Lyases 629:Cullin 569:Valine 549:Serine 529:Lysine 398:  364:, and 328:, and 297:, and 281:, and 269:The 3 232:enzyme 187:PubMed 169:Search 155:AmiGO 143:PDBsum 83:ExPASy 71:BRENDA 59:IntEnz 30:EC no. 1045:This 911:Types 639:UBE3A 234:that 119:PRIAM 1051:stub 1003:list 996:EC7 990:list 983:EC6 977:list 970:EC5 964:list 957:EC4 951:list 944:EC3 938:list 931:EC2 925:list 918:EC1 654:UBR1 644:Mdm2 396:PMID 366:1U0B 362:1LI7 358:1LI5 336:and 289:are 238:the 219:, a 199:NCBI 140:PDBe 95:KEGG 610:6.3 581:6.2 455:6.1 388:doi 354:PDB 291:AMP 275:ATP 215:In 175:PMC 131:PDB 1096:: 706:II 446:EC 394:. 384:91 382:. 368:. 360:, 340:. 324:, 320:, 301:. 293:, 277:, 225:EC 157:/ 1082:e 1075:t 1068:v 1057:. 1019:: 1005:) 1001:( 992:) 988:( 979:) 975:( 966:) 962:( 953:) 949:( 940:) 936:( 927:) 923:( 747:e 740:t 733:v 701:I 444:( 430:e 423:t 416:v 402:. 390:: 223:(

Index

EC no.
6.1.1.16
CAS no.
37318-56-2
IntEnz
IntEnz view
BRENDA
BRENDA entry
ExPASy
NiceZyme view
KEGG
KEGG entry
MetaCyc
metabolic pathway
PRIAM
profile
PDB
RCSB PDB
PDBe
PDBsum
Gene Ontology
AmiGO
QuickGO
PMC
articles
PubMed
articles
NCBI
proteins
enzymology

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