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Dihydroquinine

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InChI=1S/C20H26N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3/t13-,14-,19-,20+/m0/s1
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InChI=1/C20H26N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h4-6,8,11,13-14,19-20,23H,3,7,9-10,12H2,1-2H3/t13-,14-,19-,20+/m0/s1
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Huffman, Aarin M.; Ayariga, Joseph A.; Napier, Audrey; Robertson, Boakai K.; Abugri, Daniel A. (2022).
681: 444: 222: 671: 820: 771: 590: 465: 864: 36: 129: 193: 8: 226: 151: 78: 68: 547: 513:"Inhibition of Toxoplasma gondii Growth by Dihydroquinine and Its Mechanisms of Action" 512: 461: 534: 452: 428: 420: 497: 542: 524: 477: 416: 304: 173: 588: 791: 826: 724: 363: 529: 853: 538: 457: 436: 351: 140: 796: 658: 594: 23: 732: 714: 694: 635: 755: 737: 709: 704: 699: 689: 630: 338: 120: 801: 781: 362:
Except where otherwise noted, data are given for materials in their
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membrane damage, but does not disrupt host mitochondrial
851: 517:Frontiers in Cellular and Infection Microbiology 172: 77: 44:)-octan-2-yl]-(6-methoxyquinolin-4-yl)methanol 574: 284:O(C1N2CCC(C(CC)C2)C1)C3=CC=NC4=CC=C(OC)C=C43 490: 435:. A derivative of this molecule is used as 581: 567: 225: 150: 128: 546: 528: 450:DHQ also inhibits growth of the parasite 192: 56:)-10,11-Dihydro-6'-methoxycinchonan-9-ol 221: 852: 289:O(c4cc1c(nccc1(O)2N3CC(C2)(CC)C3)cc4)C 141: 562: 498:"Dihydroquinine chemical information" 253:Key: LJOQGZACKSYWCH-WZBLMQSHSA-N 263:Key: LJOQGZACKSYWCH-WZBLMQSHBC 163: 13: 14: 886: 589:Other drugs for disorders of the 370: 322: 316: 22: 366:(at 25 °C , 100 kPa). 748:Histone deacetylase inhibitors 504: 328: 310: 1: 483: 667:Delandistrogene moxeparvovec 7: 471: 10: 891: 682:Antisense oligonucleotides 810: 764: 746: 723: 680: 657: 621: 602: 530:10.3389/fcimb.2022.852889 445:Sharpless dihydroxylation 360: 297: 272: 237: 61: 49: 35: 30: 21: 672:Onasemnogene abeparvovec 643:clostridium histolyticum 591:musculo-skeletal system 466:reactive oxygen species 875:Quinuclidine alkaloids 870:Quinoline alkaloids 500:. ChemIndustry.com. 423:closely related to 346: g·mol 18: 860:Secondary alcohols 837:Never to phase III 468:(ROS) generation. 462:membrane potential 393:Infobox references 16: 847: 846: 453:Toxoplasma gondii 429:specific rotation 421:cinchona alkaloid 401:Chemical compound 399: 398: 206:CompTox Dashboard 110:Interactive image 103:Interactive image 882: 772:Aceneuramic acid 583: 576: 569: 560: 559: 553: 552: 550: 532: 508: 502: 501: 494: 478:Dihydroquinidine 417:organic compound 407:, also known as 383: 377: 374: 373: 345: 330: 324: 318: 312: 305:Chemical formula 230: 229: 214: 212: 196: 176: 165: 154: 143: 132: 112: 105: 81: 26: 19: 15: 890: 889: 885: 884: 883: 881: 880: 879: 850: 849: 848: 843: 842: 827:Clinical trials 806: 792:Hyaluronic acid 760: 742: 725:Glucocorticoids 719: 676: 653: 617: 606:and derivatives 598: 587: 557: 556: 509: 505: 496: 495: 491: 486: 474: 402: 395: 390: 389: 388:  ?) 379: 375: 371: 367: 343: 333: 327: 321: 315: 307: 293: 290: 285: 280: 279: 268: 265: 264: 261: 255: 254: 251: 245: 244: 233: 215: 208: 199: 179: 166: 135: 115: 95: 84: 71: 57: 45: 17:Dihydroquinine 12: 11: 5: 888: 878: 877: 872: 867: 862: 845: 844: 841: 840: 839: 838: 835: 824: 818: 812: 811: 808: 807: 805: 804: 799: 794: 789: 784: 779: 774: 768: 766: 762: 761: 759: 758: 752: 750: 744: 743: 741: 740: 735: 729: 727: 721: 720: 718: 717: 712: 707: 702: 697: 692: 686: 684: 678: 677: 675: 674: 669: 663: 661: 659:Gene therapies 655: 654: 652: 651: 646: 638: 633: 627: 625: 619: 618: 616: 615: 609: 607: 600: 599: 586: 585: 578: 571: 563: 555: 554: 503: 488: 487: 485: 482: 481: 480: 473: 470: 405:Dihydroquinine 400: 397: 396: 391: 369: 368: 364:standard state 361: 358: 357: 354: 348: 347: 341: 335: 334: 331: 325: 319: 313: 308: 303: 300: 299: 295: 294: 292: 291: 288: 286: 283: 275: 274: 273: 270: 269: 267: 266: 262: 259: 258: 256: 252: 249: 248: 240: 239: 238: 235: 234: 232: 231: 223:DTXSID70878516 218: 216: 204: 201: 200: 198: 197: 189: 187: 181: 180: 178: 177: 169: 167: 159: 156: 155: 145: 137: 136: 134: 133: 125: 123: 117: 116: 114: 113: 106: 98: 96: 89: 86: 85: 83: 82: 74: 72: 67: 64: 63: 59: 58: 51: 47: 46: 39: 33: 32: 28: 27: 9: 6: 4: 3: 2: 887: 876: 873: 871: 868: 866: 865:Phenol ethers 863: 861: 858: 857: 855: 836: 834: 831: 830: 828: 825: 822: 819: 817: 814: 813: 809: 803: 800: 798: 795: 793: 790: 788: 785: 783: 780: 778: 775: 773: 770: 769: 767: 763: 757: 754: 753: 751: 749: 745: 739: 736: 734: 731: 730: 728: 726: 722: 716: 713: 711: 708: 706: 703: 701: 698: 696: 693: 691: 688: 687: 685: 683: 679: 673: 670: 668: 665: 664: 662: 660: 656: 650: 647: 645: 644: 639: 637: 634: 632: 629: 628: 626: 624: 620: 614: 611: 610: 608: 605: 601: 596: 592: 584: 579: 577: 572: 570: 565: 564: 561: 549: 544: 540: 536: 531: 526: 522: 518: 514: 507: 499: 493: 489: 479: 476: 475: 469: 467: 464:, as well as 463: 459: 458:mitochondrial 455: 454: 448: 446: 442: 438: 437:chiral ligand 434: 430: 426: 422: 418: 414: 410: 406: 394: 387: 382: 365: 359: 355: 353: 352:Melting point 350: 349: 342: 340: 337: 336: 309: 306: 302: 301: 296: 287: 282: 281: 278: 271: 257: 247: 246: 243: 236: 228: 224: 220: 219: 217: 207: 203: 202: 195: 191: 190: 188: 186: 183: 182: 175: 171: 170: 168: 162: 158: 157: 153: 149: 146: 144: 142:ECHA InfoCard 139: 138: 131: 127: 126: 124: 122: 119: 118: 111: 107: 104: 100: 99: 97: 93: 88: 87: 80: 76: 75: 73: 70: 66: 65: 60: 55: 48: 43: 38: 34: 29: 25: 20: 797:Palovarotene 787:Chondrocytes 642: 641:Collagenase 613:Hydroquinine 612: 520: 516: 506: 492: 456:by inducing 451: 449: 431:is −148° in 412: 409:hydroquinine 408: 404: 403: 62:Identifiers 53: 50:Other names 41: 823:from market 733:Deflazacort 715:Viltolarsen 695:Drisapersen 636:Chymopapain 356:173–175 °C 298:Properties 148:100.007.578 854:Categories 756:Givinostat 738:Vamorolone 710:Nusinersen 705:Golodirsen 700:Eteplirsen 690:Casimersen 631:Bromelains 484:References 339:Molar mass 194:31J3Q51T6L 121:ChemSpider 90:3D model ( 69:CAS Number 37:IUPAC name 833:Phase III 821:Withdrawn 802:Risdiplam 782:Branaplam 539:2235-2988 419:and as a 777:Ataluren 472:See also 415:, is an 79:522-66-7 649:Trypsin 623:Enzymes 604:Quinine 548:9131874 439:in the 433:ethanol 425:quinine 386:what is 384: ( 344:326.440 161:PubChem 816:WHO-EM 545:  537:  441:AD-mix 427:. The 381:verify 378:  277:SMILES 174:121515 130:108426 31:Names 765:Other 242:InChI 92:JSmol 52:(8α,9 535:ISSN 443:for 185:UNII 595:M09 543:PMC 525:doi 413:DHQ 411:or 211:EPA 164:CID 856:: 829:: 541:. 533:. 523:. 521:12 519:. 515:. 447:. 320:26 314:20 597:) 593:( 582:e 575:t 568:v 551:. 527:: 376:Y 332:2 329:O 326:2 323:N 317:H 311:C 213:) 209:( 94:) 54:R 42:R 40:(

Index


IUPAC name
CAS Number
522-66-7
JSmol
Interactive image
Interactive image
ChemSpider
108426
ECHA InfoCard
100.007.578
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PubChem
121515
UNII
31J3Q51T6L
CompTox Dashboard
DTXSID70878516
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InChI
SMILES
Chemical formula
Molar mass
Melting point
standard state
verify
what is
Infobox references
organic compound
cinchona alkaloid

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