53:
415:. Hip dysplasia may occur at birth or develop in early life. Regardless, it does not typically produce symptoms in babies less than a year old. Occasionally one leg may be shorter than the other. The left hip is more often affected than the right. Complications without treatment can include
45:
1606:
385:, resulting in formation of bone that is weak and prone to expansion. As a result, most complications result from fracture, deformity, functional impairment and pain.
565:
126:, and cancerous forms. Various other dysplasias tend to be precancerous. The word's meanings thus cover a spectrum of histopathological variations.
288:
process. The term dysplasia is typically used when the cellular abnormality is restricted to the originating tissue, as in the case of an early,
30:
This article is about the noncancerous and precancerous changes in cells and tissues. For the clinical condition affecting the hip joint, see
569:
514:
339:
do not mature and therefore do not become healthy blood cells. Problems with blood cell formation result in some combination of
740:
713:
1179:
284:), with a corresponding decrease in the number and location of mature cells. Dysplasia is often indicative of an early
1490:
267:
1458:
780:
452:. The kidney consists of irregular cysts of varying sizes. Multicystic dysplastic kidney is a common type of renal
1095:
432:
92:
102:
senses of the term, dysplasia is sometimes differentiated from other categories of tissue change including
1601:
75:
or anatomical structure(s) resulting from such growth. Dysplasias on a mainly microscopic scale include
1126:
17:
920:
368:
80:
955:
913:
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where the socket portion does not fully cover the ball portion, resulting in an increased risk for
315:
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Dysplasia, in which cell maturation and differentiation are delayed, can be contrasted with
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1038:
533:
485:
280:
Epithelial dysplasia consists of an expansion of immature cells (such as cells of the
595:. In Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJ, Mirzaa G, Amemiya A (eds.).
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225:(reduced functionality of an organ, with decrease in the number or volume of cells)
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31:
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644:"Evaluation and Referral for Developmental Dysplasia of the Hip in Infants"
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243:(any degenerative disorder resulting from improper or faulty nutrition)
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107:
192:(congenital below-average number of cells, especially when inadequate)
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is any of various types of abnormal growth or development of cells (
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1326:
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1090:
981:
940:
925:
798:
790:
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type are replaced by cells of another mature, differentiated type.
292:
281:
52:
591:
Boyce AM, Florenzano P, de Castro LF, Collins MT (February 2015).
158:(structural differentiation loss within a cell or group of cells).
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991:
976:
222:
161:
44:
862:
794:
590:
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115:
351:. Some types have an increase in immature blood cells, called
118:. An exception is that the myelodysplasias include a range of
1157:
566:"Myelodysplastic Syndromes Treatment (PDQ®)–Patient Version"
826:
788:
444:) is a condition that results from the malformation of the
374:
27:
Abnormal development, at macroscopic or microscopical level
626:. American Academy of Orthopaedic Surgeons. October 2013.
624:"Developmental Dislocation (Dysplasia) of the Hip (DDH)"
703:
373:
Fibrous dysplasia of bone is a disorder where normal
704:Weidner N, Cote R, Suster S, Weiss L, eds. (2003).
599:. Seattle (WA): University of Washington, Seattle.
83:. Dysplasias on a mainly macroscopic scale include
730:
1607:Noninflammatory disorders of female genital tract
1583:
426:
219:Abiotrophy (loss in vitality of organ or tissue)
1173:
774:
261:
731:Cotran RS, Kumar V, Collins T, eds. (1999).
593:"Fibrous Dysplasia/McCune–Albright Syndrome"
362:
237:(decrease in the volume of cells or tissues)
231:(increase in the volume of cells or tissues)
309:
1180:
1166:
781:
767:
637:
635:
633:
268:
254:
659:
641:
560:
558:
556:
618:
616:
614:
515:List of biological development disorders
114:, and dysplasias are thus generally not
51:
43:
735:(6th ed.). London: W.B. Saunders.
630:
134:
14:
1584:
553:
1161:
762:
684:Multicystic Dysplastic Kidney Imaging
611:
568:. NCI. 12 August 2015. Archived from
388:
129:
733:Robbins Pathologic Basis of Disease
642:Shaw BA, Segal LS (December 2016).
24:
1491:Fluorescence in situ hybridization
696:
210:(development of new cell function)
25:
1618:
584:
456:disease, and it is a cause of an
1459:Oral and maxillofacial pathology
476:'bad' or 'difficult' and πλάσις
393:
302:, in which cells of one mature,
164:(organ or part of organ missing)
676:
526:
13:
1:
1187:
1096:Clonally transmissible cancer
520:
438:Multicystic dysplastic kidney
433:Multicystic dysplastic kidney
427:Multicystic dysplastic kidney
93:multicystic dysplastic kidney
480:'formation'. The equivalent
463:
7:
503:
10:
1623:
1127:Index of oncology articles
430:
397:
366:
313:
176:(change in cell or tissue
170:(connective tissue growth)
138:
36:
29:
1499:
1424:
1195:
1114:
1067:
1025:
1000:
964:
886:
845:
812:
805:
708:. London: W.B. Saunders.
706:Modern Surgical Pathology
534:"Definition of dysplasia"
407:is an abnormality of the
369:Fibrous dysplasia of bone
363:Fibrous dysplasia of bone
321:Myelodysplastic syndromes
198:(conversion in cell type)
81:fibrous dysplasia of bone
355:, in the bone marrow or
316:Myelodysplastic syndrome
310:Myelodysplastic syndrome
204:(abnormal proliferation)
186:(proliferation of cells)
89:myelodysplastic syndrome
37:Not to be confused with
1566:Microbiological culture
1196:Principles of pathology
1049:Prostate cancer staging
1013:Paraneoplastic syndrome
1087:Tumor suppressor genes
1054:Gleason grading system
1008:Precancerous condition
661:10.1542/peds.2016-3107
57:
49:
1529:Diagnostic immunology
1354:Programmed cell death
1322:Liquefactive necrosis
1106:Carcinogenic bacteria
846:Malignant progression
349:low white blood cells
98:In one of the modern
55:
48:Normal squamous cells
47:
1524:Medical microbiology
1519:Transfusion medicine
1476:Immunohistochemistry
1426:Anatomical pathology
1317:Coagulative necrosis
1059:Dukes classification
141:Epithelial dysplasia
135:Epithelial dysplasia
77:epithelial dysplasia
71:), and the abnormal
1481:Electron microscopy
1449:Molecular pathology
1327:Gangrenous necrosis
1259:Cellular adaptation
878:Sentinel lymph node
486:classical compounds
484:, in parallel with
341:low red blood cells
148:-plasia and -trophy
1602:Induced stem cells
1509:Clinical chemistry
1501:Clinical pathology
1486:Immunofluorescence
1454:Forensic pathology
1434:Surgical pathology
1342:Fibrinoid necrosis
926:Respiratory system
331:in which immature
58:
50:
1579:
1578:
1546:Mass spectrometry
1155:
1154:
1142:Cancer and nausea
1021:
1020:
858:Carcinoma in situ
742:978-0-7216-7335-6
715:978-0-7216-7253-3
572:on 5 October 2016
450:fetal development
413:joint dislocation
389:Macroscopic scale
381:is replaced with
327:) are a group of
278:
277:
130:Microscopic scale
100:histopathological
69:macroscopic scale
65:microscopic scale
16:(Redirected from
1614:
1466:Gross processing
1332:Caseous necrosis
1182:
1175:
1168:
1159:
1158:
956:Endocrine system
921:Digestive system
810:
809:
783:
776:
769:
760:
759:
754:
727:
691:
680:
674:
673:
663:
654:(6): e20163107.
639:
628:
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609:
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588:
582:
581:
579:
577:
562:
551:
550:
548:
547:
530:
482:surface analysis
270:
263:
256:
145:
144:
56:Dysplastic cells
21:
1622:
1621:
1617:
1616:
1615:
1613:
1612:
1611:
1582:
1581:
1580:
1575:
1534:Immunopathology
1514:Hematopathology
1495:
1420:
1191:
1186:
1156:
1151:
1110:
1063:
1017:
996:
960:
882:
841:
801:
787:
757:
743:
716:
699:
697:Further reading
694:
681:
677:
640:
631:
622:
621:
612:
589:
585:
575:
573:
564:
563:
554:
545:
543:
539:Merriam-Webster
532:
531:
527:
523:
506:
466:
435:
429:
419:, limping, and
402:
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391:
371:
365:
318:
312:
274:
143:
137:
132:
42:
35:
28:
23:
22:
15:
12:
11:
5:
1620:
1610:
1609:
1604:
1599:
1597:Histopathology
1594:
1577:
1576:
1574:
1573:
1568:
1563:
1558:
1556:Flow cytometry
1553:
1551:Chromatography
1548:
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1537:
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1531:
1526:
1521:
1516:
1511:
1505:
1503:
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1471:Histopathology
1468:
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1103:
1098:
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1084:
1079:
1073:
1071:
1069:Carcinogenesis
1065:
1064:
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1041:
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1023:
1022:
1019:
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989:
984:
979:
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951:Nervous system
948:
943:
938:
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928:
923:
918:
917:
916:
914:nasopharyngeal
911:
906:
901:
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517:
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502:
465:
462:
458:abdominal mass
431:Main article:
428:
425:
398:Main article:
395:
392:
390:
387:
383:fibrous tissue
367:Main article:
364:
361:
314:Main article:
311:
308:
304:differentiated
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139:Main article:
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26:
9:
6:
4:
3:
2:
1619:
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1440:
1439:Cytopathology
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1427:
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1407:
1405:
1401:
1398:
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1383:Accumulations
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1253:
1252:Wound healing
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985:
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934:
932:
929:
927:
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922:
919:
915:
912:
910:
907:
905:
904:oropharyngeal
902:
900:
897:
896:
895:
894:Head and neck
892:
891:
889:
885:
879:
876:
874:
873:Primary tumor
871:
869:
866:
864:
861:
859:
856:
854:
851:
850:
848:
844:
838:
835:
833:
830:
828:
825:
823:
820:
819:
817:
815:
814:Benign tumors
811:
808:
804:
800:
796:
792:
784:
779:
777:
772:
770:
765:
764:
761:
752:
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511:
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501:
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493:
492:
487:
483:
479:
475:
471:
470:Ancient Greek
461:
459:
455:
451:
447:
443:
439:
434:
424:
422:
421:low back pain
418:
414:
410:
406:
405:Hip dysplasia
401:
400:Hip dysplasia
394:Hip dysplasia
386:
384:
380:
376:
370:
360:
358:
354:
350:
346:
345:low platelets
342:
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96:
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90:
86:
85:hip dysplasia
82:
78:
74:
70:
67:) or organs (
66:
62:
54:
46:
40:
33:
32:Hip dysplasia
19:
1541:Enzyme assay
1387:
1382:
1371:Karyorrhexis
1347:Myocytolysis
1337:Fat necrosis
1280:
1242:Inflammation
1230:Hemodynamics
1223:Pathogenesis
852:
789:Overview of
732:
705:
682:
678:
651:
647:
597:Gene Reviews
596:
586:
574:. Retrieved
570:the original
544:. Retrieved
537:
528:
510:Pleomorphism
495:
489:
477:
473:
467:
460:in infants.
441:
437:
436:
404:
403:
372:
324:
320:
319:
297:
289:
279:
173:
124:precancerous
97:
60:
59:
1395:Hemosiderin
1276:Hyperplasia
1271:Hypertrophy
1247:Cell damage
1137:Cancer pain
1077:Cancer cell
822:Hyperplasia
337:bone marrow
333:blood cells
229:Hypertrophy
208:Prosoplasia
184:Hyperplasia
168:Desmoplasia
104:hyperplasia
1586:Categories
1561:Blood bank
1404:Lipofuscin
1400:Lipochrome
1376:Karyolysis
1305:Cell death
1286:Metaplasia
1082:Carcinogen
946:Urogenital
887:Topography
868:Metastasis
832:Pseudocyst
806:Conditions
648:Pediatrics
576:27 October
546:2019-09-09
541:dictionary
521:References
300:metaplasia
286:neoplastic
235:Hypotrophy
196:Metaplasia
190:Hypoplasia
108:metaplasia
18:Dysplastic
1416:Steatosis
1359:Apoptosis
1296:Glandular
1281:Dysplasia
1213:Neoplasia
1208:Infection
1189:Pathology
1101:Oncovirus
1091:oncogenes
1044:Ann Arbor
987:Papilloma
972:Carcinoma
965:Histology
909:laryngeal
853:Dysplasia
837:Hamartoma
689:eMedicine
464:Etymology
417:arthritis
409:hip joint
241:Dystrophy
202:Neoplasia
178:phenotype
174:Dysplasia
156:Anaplasia
116:cancerous
112:neoplasia
73:histology
61:Dysplasia
39:Dyscrasia
1592:Oncology
1571:Serology
1366:Pyknosis
1312:Necrosis
1291:Squamous
1235:Ischemia
1122:Research
982:Blastoma
799:oncology
751:39465455
724:50244347
670:27940740
605:25719192
504:See also
293:neoplasm
282:ectoderm
1444:Autopsy
1409:Melanin
1389:pigment
1266:Atrophy
1203:Disease
1132:History
1031:grading
1027:Staging
992:Adenoma
977:Sarcoma
497:-plasia
448:during
335:in the
329:cancers
290:in-situ
223:Atrophy
162:Aplasia
863:Cancer
795:cancer
791:tumors
749:
739:
722:
712:
668:
603:
478:plasis
454:cystic
446:kidney
379:marrow
353:blasts
347:, and
120:benign
110:, and
91:, and
1218:Cause
1115:Misc.
1001:Other
941:Blood
488:, is
472:δυσ-
468:From
357:blood
1147:Diet
936:Skin
931:Bone
899:oral
827:Cyst
797:and
747:OCLC
737:ISBN
720:OCLC
710:ISBN
666:PMID
601:PMID
578:2016
491:dys-
474:dys-
442:MCDK
377:and
375:bone
79:and
1039:TNM
687:at
656:doi
652:138
325:MDS
1588::
793:,
745:.
718:.
664:.
650:.
646:.
632:^
613:^
555:^
536:.
500:.
494:+
423:.
359:.
343:,
295:.
122:,
106:,
95:.
87:,
1402:/
1181:e
1174:t
1167:v
1089:/
1029:/
782:e
775:t
768:v
753:.
726:.
672:.
658::
607:.
580:.
549:.
440:(
323:(
269:e
262:t
255:v
180:)
41:.
34:.
20:)
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