1327:(IQEHC) published results of a meta-analysis of clinical trial data for reboxetine in acute depression, which included data on about 3,000 subjects that Pfizer had never published but had mentioned; IQEHC had combed through Pfizer's publications and reboxetine approvals and had determined this data was missing from the publication record. The analysis of the complete data set yielded a result that reboxetine was not more effective than placebo but had more side effects than placebo and more than
708:, including unpublished data, published data on reboxetine overestimated the benefit of reboxetine versus placebo by up to 115% and reboxetine versus SSRIs by up to 23%, and also underestimated harm, concluding that reboxetine was an ineffective and potentially harmful antidepressant. The study also showed that nearly three quarters of the data on patients who took part in trials of reboxetine had not been published by Pfizer.
40:
700:
said in
September 2011 that the study had several limitations, and that "Overall the balance of benefits and risks for reboxetine remains positive in its authorised indication." A UK and Europe-wide review of available efficacy and safety data has confirmed that reboxetine has benefit over placebo in
720:
In a randomised double-blind placebo-controlled trial reboxetine significantly improved the symptoms of panic disorder. Another randomised controlled trial that compared paroxetine to reboxetine found that paroxetine significantly outperformed reboxetine as a treatment for panic disorder. Despite
692:
There has been much debate as to whether reboxetine is more efficacious than placebo in the treatment of depression. According to a 2009 meta-analysis of 12 second-generation antidepressants, reboxetine was no more effective than placebo, and was "significantly less" effective and less acceptable
750:. Individual trials and meta-analysis suggest that reboxetine can attenuate antipsychotic-induced weight gain and there is some evidence of a benefit on depressive, and possibly other symptoms of schizophrenia when added to antipsychotic treatment.
2617:
711:
A 2018 systematic review and network meta-analysis comparing the efficacy and acceptability of 21 antidepressant drugs concluded that reboxetine was more effective than placebo but significantly less efficacious than other antidepressants tested.
1319:
It was first approved in Europe in 1997 and was provisionally approved by the FDA in 1999. In 2001 the FDA issued Pfizer a "not approvable" letter based on clinical trials the FDA had required when it issued the preliminary approval letter.
2549:
Kishi T, Mukai T, Matsuda Y, Moriwaki M, Iwata N (November 2013). "Efficacy and safety of noradrenalin reuptake inhibitor augmentation therapy for schizophrenia: a meta-analysis of double-blind randomized placebo-controlled trials".
729:
Numerous clinical trials have provided support for the efficacy of reboxetine in the treatment of attention deficit hyperactivity disorder (ADHD) in both the short and long-term and in both children/adolescents and adults.
1910:
Versiani M, Cassano G, Perugi G, Benedetti A, Mastalli L, Nardi A, Savino M (January 2002). "Reboxetine, a selective norepinephrine reuptake inhibitor, is an effective and well-tolerated treatment for panic disorder".
1946:
Bertani A, Perna G, Migliarese G, Di
Pasquale D, Cucchi M, Caldirola D, Bellodi L (September 2004). "Comparison of the treatment with paroxetine and reboxetine in panic disorder: a randomized, single-blind study".
2241:
Quintero J, López-Muñoz F, Alamo C, Loro M, García-Campos N (November 2010). "Reboxetine for ADHD in children non-responders or with poor tolerance to methylphenidate: a prospective long-term open-label study".
2156:
Riahi F, Tehrani-Doost M, Shahrivar Z, Alaghband-Rad J (November 2010). "Efficacy of reboxetine in adults with attention-deficit/hyperactivity disorder: a randomized, placebo-controlled clinical trial".
2203:
Toren P, Ratner S, Weizman A, Lask M, Ben-Amitay G, Laor N (December 2007). "Reboxetine maintenance treatment in children with attention-deficit/hyperactivity disorder: a long-term follow-up study".
2966:
Cocchiara G, Battaglia R, Pevarello P, Strolin
Benedetti M (1991). "Comparison of the disposition and of the metabolic pattern of Reboxetine, a new antidepressant, in the rat, dog, monkey and man".
792:
Common (1–10%) adverse effects include loss of appetite, agitation, anxiety, headache, restlessness, tingling sensations, distorted sense of taste, difficulty with seeing near or far (problems with
2725:
Wienkers LC, Allievi C, Hauer MJ, Wynalda MA (November 1999). "Cytochrome P-450-mediated metabolism of the individual enantiomers of the antidepressant agent reboxetine in human liver microsomes".
800:, relaxing of blood vessels leading to low blood pressure, high blood pressure, vomiting, rash, sensation of incomplete bladder emptying, urinary tract infection, painful or difficult urination,
8979:
5585:
7559:
1344:
Edronax is the brand name of reboxetine in every
English-speaking country that has approved it for clinical use. Brand names include (where † denotes a product that is no longer marketed):
705:
1725:"Reboxetine for acute treatment of major depression: systematic review and meta-analysis of published and unpublished placebo and selective serotonin reuptake inhibitor controlled trials"
176:
2118:
Ratner S, Laor N, Bronstein Y, Weizman A, Toren P (May 2005). "Six-week open-label reboxetine treatment in children and adolescents with attention-deficit/hyperactivity disorder".
1863:"Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis"
721:
this discouraging finding an open-label trial examining the efficacy of reboxetine in SSRI-resistant panic disorder demonstrated significant benefit from reboxetine treatment.
8202:
3176:
2285:
El-Giamal N, de Zwaan M, Bailer U, Lennkh C, Schüssler P, Strnad A, Kasper S (November 2000). "Reboxetine in the treatment of bulimia nervosa: a report of seven cases".
545:
10842:
8638:
2080:
Tehrani-Doost M, Moallemi S, Shahrivar Z (April 2008). "An open-label trial of reboxetine in children and adolescents with attention-deficit/hyperactivity disorder".
10837:
7552:
7195:
1566:
5339:
1561:[Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese).
8671:
6291:
1190:
1148:
5344:
10897:
9014:
7762:
5630:
807:
A 2009 meta-analysis found that reboxetine was significantly less well tolerated than the other 11 second-generation antidepressants compared in the analysis.
8633:
131:
1182:(SERT). Despite this selectivity, reboxetine does slightly inhibit the reuptake of serotonin at therapeutic doses. It does not interact with or inhibit the
7545:
7525:
1990:
Dannon PN, Iancu I, Grunhaus L (October 2002). "The efficacy of reboxetine in the treatment-refractory patients with panic disorder: an open label study".
1775:
Cipriani A, Furukawa TA, Salanti G, Geddes JR, Higgins JP, Churchill R, Watanabe N, Nakagawa A, Omori IM, McGuire H, Tansella M, Barbui C (February 2009).
7444:
1324:
697:
5324:
2752:
Weiss J, Dormann SM, Martin-Facklam M, Kerpen CJ, Ketabi-Kiyanvash N, Haefeli WE (April 2003). "Inhibition of P-glycoprotein by newer antidepressants".
7907:
615:
189:
4106:
3196:
7887:
7186:
6177:
2892:"Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine"
6258:
5136:
8064:
5053:
7842:
10959:
10501:
10496:
9777:
9772:
9591:
8502:
7812:
7073:
6324:
571:
11052:
8664:
8197:
7637:
7632:
7513:
1776:
5369:
5364:
2457:"Attenuation of olanzapine-induced weight gain with reboxetine in patients with schizophrenia: a double-blind, placebo-controlled study"
10280:
7767:
7519:
2038:"A comparison of the effects of reboxetine and placebo on reaction time in adults with Attention Deficit-Hyperactivity Disorder (ADHD)"
781:: one says the combination is possible with monitoring of side effects but the product informations indicate them as contraindicated.
5359:
5334:
5329:
789:
Very common (>10% incidence) adverse effects include insomnia, dizziness, dry mouth, constipation, nausea, and excessive sweating.
10877:
10618:
9009:
9004:
8044:
7987:
7952:
7927:
7832:
7657:
7652:
6075:
5625:
5520:
5354:
11002:
8069:
7438:
7263:
1600:
668:
2618:"The Prescriber's Guide to Classic MAO Inhibitors (Phenelzine, Tranylcypromine, Isocarboxazid) for Treatment-Resistant Depression"
1232:-desethylreboxetine, and there are also three minor metabolites—Phenol A, Phenol B, and UK1, Phenol B being the most minor.
599:
InChI=1S/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3/t18-,19-/m1/s1
8342:
6119:
5269:
8999:
8657:
7507:
5525:
5349:
3010:
Melloni M; et al. (1984). "Potential antidepressant agents. α-aryloxy-benzyl derivatives of ethanolamine and morpholine".
11067:
7130:
2874:
2849:
2704:
2600:
3636:
1331:; the paper led to widespread and sharp criticism of Pfizer, and stronger calls for publication of all clinical trial data.
7179:
3223:
2328:
Fassino S, Daga GA, Boggio S, Garzaro L, Pierò A (September 2004). "Use of reboxetine in bulimia nervosa: a pilot study".
1558:
11062:
10986:
7449:
6357:
5683:
675:. Although its effectiveness as an antidepressant has been challenged in multiple published reports, its popularity has
11032:
9352:
6225:
5314:
4615:
4521:
3291:
3083:
2815:. University of North Carolina at Chapel Hill and the United States National Institute of Mental Health. Archived from
1554:
622:
7579:
7489:
2939:
Melloni P, Della Torre A, Lazzari E, Mazzini G, Meroni M (1985). "Configuration studies on 2--morpholine FCE 20124".
1167:
1116:
644:
591:
10801:
7568:
7147:
4620:
1131:
1777:"Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis"
7172:
5020:
4714:
4625:
301:
161:
1723:
Eyding D, Lelgemann M, Grouven U, Härter M, Kromp M, Kaiser T, Kerekes MF, Gerken M, Wieseler B (October 2010).
11047:
11006:
8002:
7598:
5309:
5279:
4605:
4600:
4300:
4216:
2804:
10062:
6068:
5299:
5284:
4684:
4595:
4590:
4131:
1559:"RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial"
10982:
8699:
8680:
8628:
5113:
5103:
4957:
4857:
4630:
4412:
1562:
1060:
1047:
778:
418:
5304:
11037:
10346:
9622:
7692:
7471:
6730:
6663:
5724:
5264:
5151:
5146:
4862:
4101:
2670:
701:
its authorised indication. Efficacy was clearly shown in patients with severe or very severe depression.
475:
9341:
8853:
8016:
7742:
7612:
7483:
6493:
6401:
5379:
4797:
4719:
4093:
2616:
Van den Eynde V, Abdelmoemin WR, Abraham MM, Amsterdam JD, Anderson IM, Andrade C, et al. (2023).
1308:
and was first published in 1984; Farmitalia did the first clinical studies. Farmitalia was acquired by
1175:
945:
4270:
1835:
7454:
6505:
5432:
4196:
3611:
1674:
671:(ADHD). It is approved for use in many countries worldwide, but has not been approved for use in the
656:
4265:
2371:
Nevéus T (2006). "Reboxetine in therapy-resistant enuresis: results and pathogenetic implications".
1704:
11027:
8602:
7320:
7312:
6061:
4867:
4704:
3756:
3351:
3216:
10819:
7732:
7226:
7135:
5166:
5161:
4852:
4285:
4226:
4176:
4171:
4121:
3721:
3061:
2456:
2455:
Poyurovsky M, Isaacs I, Fuchs C, Schneidman M, Faragian S, Weizman R, Weizman A (February 2003).
112:
73:
17:
2592:
2586:
2416:"Stimulant and anticataplectic effects of reboxetine in patients with narcolepsy: a pilot study"
1861:
Cipriani A, Furukawa TA, Salanti G, Chaimani A, Atkinson LZ, Ogawa Y, et al. (April 2018).
11057:
10998:
10994:
10401:
9677:
9107:
9060:
8021:
7206:
6970:
6441:
5764:
5640:
5389:
5108:
4792:
4295:
4181:
4141:
4126:
240:
7537:
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10119:
10051:
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8827:
8587:
8536:
8497:
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7259:
6411:
5605:
5241:
4965:
4787:
3621:
3606:
3598:
1305:
1241:
1179:
1100:
926:
738:
A case series and open-label pilot study demonstrated the efficacy of reboxetine in treating
556:
5703:
407:
11042:
10990:
10862:
10391:
9935:
9667:
9097:
9076:
8688:
8582:
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8427:
8267:
8212:
8127:
7917:
7465:
7090:
7005:
5939:
5450:
4847:
4754:
4724:
4531:
4368:
4146:
3616:
3296:
3286:
1183:
1086:
1073:
963:
693:
than the other drugs in treating the acute-phase of adults with unipolar major depression.
435:
427:
342:
334:
267:
5698:
3046:
3029:
2415:
8:
10676:
10521:
10386:
10114:
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8467:
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5025:
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3209:
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325:
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3641:
3626:
3278:
3152:
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3127:
2991:
2916:
2891:
2777:
2526:
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2396:
2353:
2310:
2267:
2182:
2131:
2054:
2037:
2015:
1972:
1887:
1862:
1807:
1749:
1724:
1692:
1653:
774:, prostatic hypertrophy, those hypersensitive to reboxetine or any of its excipients.
743:
86:
2952:
1878:
1795:
10752:
9490:
9197:
8772:
8607:
8327:
8207:
8087:
7234:
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6528:
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5374:
5226:
4877:
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1964:
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7080:
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5058:
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4580:
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2629:
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2471:
2427:
2380:
2337:
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2251:
2212:
2186:
2166:
2127:
2089:
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1956:
1920:
1882:
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1791:
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767:
491:
367:
222:
144:
3101:
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10827:
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10632:
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8919:
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7343:
7249:
7244:
7230:
7019:
7013:
6826:
6200:
5934:
5427:
5236:
5211:
5171:
5010:
4927:
4882:
4749:
4744:
4664:
4660:
4476:
4249:
4231:
3701:
3399:
3177:"Did Sneaky Publication Tactics Help Pfizer's Reboxetine Slip Through to Market?"
1031:
1017:
1004:
991:
978:
739:
561:
250:
230:
8649:
8034:
8026:
6088:
6044:
5693:
5688:
5668:
5663:
5658:
5653:
10656:
10640:
10636:
10562:
10285:
9951:
9943:
9556:
9322:
9045:
8797:
8312:
7962:
7757:
7702:
7477:
7141:
6583:
6292:
6190:
6084:
5929:
5924:
5729:
5191:
4896:
4734:
4442:
3510:
3404:
3359:
3321:
2475:
2414:
Larrosa O, de la Llave Y, Bario S, Granizo JJ, Garcia-Borreguero D (May 2001).
2341:
1449:
1377:
1149:
863:
664:
648:
8038:
2633:
2384:
2255:
11021:
10912:
10696:
10692:
10662:
10628:
10602:
10592:
10547:
10511:
10371:
10315:
10154:
10094:
10016:
9996:
9979:
9957:
9878:
9873:
9823:
9787:
9647:
9586:
9312:
8832:
8817:
8777:
8592:
8422:
8392:
8332:
8282:
8277:
8167:
8137:
8083:
7912:
7727:
7662:
7422:
7391:
7351:
7031:
6978:
6766:
6638:
6613:
6608:
6548:
6523:
6009:
5909:
5859:
5774:
5015:
4942:
4917:
4832:
4827:
4802:
4767:
4640:
4280:
4221:
3766:
3711:
3550:
3545:
3540:
3535:
3505:
3379:
3301:
2432:
742:. Reboxetine may also have efficacy in treating therapy-resistant paediatric
672:
8929:
8924:
5505:
5500:
2965:
2765:
746:. A pilot study demonstrated the efficacy of reboxetine in the treatment of
10847:
10742:
10732:
10557:
10552:
10396:
10366:
10254:
10124:
10002:
9914:
9883:
9838:
9833:
9828:
9672:
9642:
9530:
9439:
9399:
9302:
9222:
9112:
9102:
8914:
8909:
8894:
8889:
8868:
8507:
8437:
8432:
8347:
8157:
8147:
8098:
8079:
7877:
7797:
7787:
7076:
7064:
6974:
6881:
6811:
6801:
6653:
6643:
6543:
6538:
6461:
6456:
6436:
6421:
6375:
6137:
6101:
5964:
5914:
5834:
5814:
5809:
5789:
5784:
5739:
5495:
5490:
5480:
5465:
5404:
4975:
4970:
4947:
4907:
4739:
4645:
4561:
4491:
4472:
4467:
4452:
4325:
4255:
4206:
3884:
3849:
3814:
3681:
3520:
3341:
3326:
3161:
2925:
2773:
2738:
2651:
2571:
2535:
2483:
2441:
2392:
2349:
2306:
2263:
2224:
2178:
2139:
2101:
2063:
2011:
1968:
1932:
1896:
1803:
1758:
1429:
1276:)-isomers. The active ingredient of reboxetine is a racemic mixture of two
851:
797:
139:
31:
10207:
Selective serotonin reuptake inhibitors and serotonin receptor modulators:
5678:
5673:
2987:
2216:
2093:
1960:
10917:
10907:
10852:
10823:
10773:
10717:
10670:
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10567:
10516:
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10381:
10351:
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4063:
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3952:
3929:
3924:
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3879:
3874:
3869:
3864:
3859:
3839:
3834:
3799:
3691:
3646:
3565:
3525:
3472:
3369:
3336:
3268:
2869:(2013 ed.). Adelaide: The Australian Medicines Handbook Unit Trust.
1924:
1437:
1417:
1409:
1194:
891:
867:
5648:
2907:
2615:
2155:
387:
10966:
10922:
10887:
10814:
10777:
10737:
10707:
10684:
10648:
10597:
10582:
10466:
10451:
10421:
10411:
10406:
10361:
10356:
10295:
10290:
10275:
10249:
10219:
10214:
10199:
10194:
10169:
10164:
10134:
10129:
10109:
10104:
10028:
10007:
9990:
9985:
9868:
9858:
9742:
9727:
9697:
9687:
9682:
9637:
9632:
9566:
9561:
9520:
9500:
9485:
9460:
9444:
9414:
9292:
9282:
9267:
9212:
9202:
9192:
9172:
9162:
9147:
9142:
9065:
9055:
9050:
8863:
8756:
8751:
8572:
8552:
8512:
8487:
8442:
8387:
8377:
8372:
8362:
8337:
8302:
8257:
8252:
8232:
8217:
8177:
8142:
8074:
8059:
8049:
7802:
7792:
7737:
7697:
7682:
7417:
7376:
7371:
7333:
7302:
7279:
7214:
7112:
7098:
7084:
6990:
6986:
6982:
6936:
6906:
6901:
6896:
6876:
6846:
6836:
6796:
6781:
6761:
6648:
6628:
6598:
6578:
6558:
6518:
6466:
6451:
6446:
6406:
6370:
6342:
6271:
6248:
6195:
6167:
6162:
6157:
6142:
6132:
5994:
5979:
5969:
5919:
5889:
5884:
5854:
5844:
5769:
5734:
5515:
5422:
5399:
5128:
5118:
5040:
5030:
5005:
5000:
4985:
4912:
4892:
4887:
4842:
4782:
4772:
4762:
4729:
4585:
4575:
4566:
4556:
4551:
4516:
4506:
4501:
4447:
4432:
4402:
4378:
4363:
4355:
4350:
4320:
4290:
4275:
4260:
4201:
4191:
4073:
4068:
4058:
4020:
4015:
3982:
3977:
3947:
3939:
3829:
3746:
3716:
3706:
3656:
3651:
3555:
3515:
3457:
3452:
3437:
3374:
3364:
3316:
3258:
3253:
3248:
3240:
2979:
2800:
1328:
1277:
887:
879:
875:
871:
847:
747:
521:
398:
2642:
1740:
10954:
10902:
10872:
10867:
10787:
10769:
10765:
10722:
10680:
10623:
10572:
10491:
10461:
10325:
10244:
10234:
10229:
10224:
10149:
10144:
10024:
10020:
9909:
9899:
9848:
9767:
9737:
9601:
9551:
9470:
9465:
9434:
9429:
9389:
9287:
9277:
9242:
9167:
9137:
9070:
9030:
8994:
8899:
8884:
8858:
8822:
8812:
8741:
8736:
8731:
8726:
8412:
8407:
8382:
8357:
8352:
8322:
8272:
8262:
8242:
8112:
7897:
7892:
7882:
7707:
7687:
7677:
7672:
7627:
7495:
7361:
7356:
7328:
7297:
7000:
6886:
6821:
6816:
6791:
6786:
6776:
6771:
6681:
6623:
6588:
6568:
6533:
6489:
6347:
6304:
6276:
6210:
6152:
6029:
6004:
5869:
5839:
5829:
5754:
5620:
5470:
5460:
5394:
5384:
5231:
5221:
5093:
5088:
5083:
5078:
5073:
4812:
4635:
4541:
4526:
4511:
4462:
4417:
4236:
4040:
4030:
4025:
4005:
3962:
3889:
3809:
3804:
3794:
3779:
3751:
3731:
3726:
3696:
3671:
3661:
3588:
3583:
3578:
3482:
3467:
3462:
3394:
3331:
3311:
3263:
3232:
2170:
1842:. Medicines and Healthcare products Regulatory Agency. September 2011
1497:
1485:
1365:
1309:
1225:
1221:)-(+)-enantiomers of reboxetine are predominantly metabolized by the
883:
660:
353:
280:
6325:
6178:
5294:
5289:
2003:
1679:. The Royal Pharmaceutical Society of Great Britain. 8 November 2011
10941:
10892:
10882:
10781:
10727:
10688:
10666:
10456:
10446:
10239:
10032:
9975:
9961:
9732:
9722:
9424:
9409:
9374:
9232:
9227:
9217:
9187:
8989:
8746:
8566:
8492:
8307:
8297:
8117:
7872:
7862:
7822:
7817:
7807:
7772:
7722:
7717:
7622:
7459:
6751:
6707:
6431:
6416:
6259:
6040:
5904:
5864:
5824:
5819:
5615:
5246:
5206:
5098:
5048:
4995:
4990:
4937:
4932:
4922:
4807:
4709:
4655:
4496:
4397:
4340:
4078:
4053:
3997:
3967:
3854:
3824:
3819:
3774:
3686:
3666:
3573:
3530:
3487:
3414:
3306:
2816:
1441:
1425:
816:
763:
759:
455:
378:
2120:
Journal of the
American Academy of Child and Adolescent Psychiatry
544:
10747:
10577:
10530:
10526:
10476:
10471:
10426:
10416:
10376:
10305:
10184:
9853:
9806:
9802:
9752:
9747:
9702:
9692:
9652:
9576:
9495:
9257:
9247:
9237:
9207:
9152:
8974:
8969:
8964:
8959:
8954:
8949:
8944:
8904:
8802:
8721:
8562:
8542:
8122:
8093:
7947:
7942:
7937:
7932:
7922:
7826:
7712:
7647:
7642:
6573:
6019:
5944:
5899:
5600:
5595:
5590:
5580:
5575:
5570:
5565:
5560:
5555:
5550:
5545:
5485:
5442:
5414:
5274:
5196:
5186:
5068:
4427:
4310:
4186:
3987:
3909:
3904:
3899:
3789:
3784:
3477:
3447:
1945:
1509:
1393:
1389:
1385:
1381:
1373:
1369:
815:
Reboxetine is considered a relatively low-risk antidepressant in
7196:
2938:
2751:
2036:
Hashemian F, Mohammadian S, Riahi F, Ghaeli P, Ghodsi D (2011).
10757:
10486:
10431:
10174:
10012:
9762:
9707:
9515:
9262:
8939:
8152:
7972:
7782:
7567:
6297:
6120:
6024:
5974:
5959:
5540:
5535:
5530:
5475:
4407:
4391:
4387:
4383:
3919:
3844:
3432:
3427:
3422:
2502:"Selective noradrenaline reuptake inhibitors for schizophrenia"
2454:
2035:
1860:
1489:
1445:
1433:
1421:
1413:
1405:
1397:
1313:
1222:
1154:
Tooltip G protein-coupled inwardly-rectifying potassium channel
859:
855:
839:
804:, erectile dysfunction, ejaculatory pain or delay, and chills.
652:
466:
259:
2842:
2413:
2079:
1909:
8522:
6488:
5799:
5719:
5063:
4980:
4699:
4536:
4161:
4116:
3442:
3201:
2284:
1774:
1533:
1521:
1493:
1473:
1461:
1401:
1353:
535:
285:
255:
39:
2240:
1722:
1189:
Reboxetine has been found to inhibit both brain and cardiac
10831:
6358:
4610:
4156:
4136:
3957:
2724:
724:
446:
9353:
6226:
3084:"Reboxetine Doesn't Work. But That's Not the Real Problem"
2745:
2591:(65 ed.). London, UK: Pharmaceutical Press. pp.
2117:
7580:
2754:
The
Journal of Pharmacology and Experimental Therapeutics
2584:
2548:
1117:
10802:
2968:
European
Journal of Drug Metabolism and Pharmacokinetics
2327:
1132:
2932:
2889:
10344:
Serotonin–norepinephrine–dopamine reuptake inhibitors:
9620:
Serotonin–norepinephrine–dopamine reuptake inhibitors:
8003:
7599:
2839:
2202:
704:
According to a systematic review and meta-analysis by
10063:
2844:(12th ed.). New York: McGraw-Hill Professional.
8700:
7526:
Serotonin-norepinephrine-dopamine reuptake inhibitor
6330:
Tooltip
Serotonin antagonist and reuptake inhibitors
6183:
Tooltip Serotonin–norepinephrine reuptake inhibitors
2499:
777:
There is conflicting information regarding use with
7445:
Attention deficit hyperactivity disorder management
6664:
6264:
Tooltip Norepinephrine–dopamine reuptake inhibitors
2720:
2718:
2716:
1989:
1325:
Institute for Quality and Efficiency in Health Care
862:. Reboxetine is an intermediate-level inhibitor of
9342:
2673:. UK Electronic Medicines Compendium. October 2015
2205:Journal of Child and Adolescent Psychopharmacology
2082:Journal of Child and Adolescent Psychopharmacology
1601:"PRODUCT INFORMATION EDRONAX® Reboxetine mesilate"
946:
8679:
6506:
4107:1-Methylamino-1-(3,4-methylenedioxyphenyl)propane
2697:The Maudsley prescribing guidelines in psychiatry
2694:
11019:
6729:
2713:
2500:Matthews PR, Horder J, Pearce M (January 2018).
866:, which gives it the potential to interact with
366:
7066:
6125:Tooltip Selective serotonin reuptake inhibitors
5137:1-Benzyl-4-(2-(diphenylmethoxy)ethyl)piperidine
2890:Kobayashi T, Washiyama K, Ikeda K (June 2010).
1636:Holm KJ, Spencer CM (July 1999). "Reboxetine".
1312:in 1993, and Pharmacia in turn was acquired by
341:
333:
8498:Trimetaphan camsilate (trimethaphan camsylate)
7276:
7207:
2373:Scandinavian Journal of Urology and Nephrology
2113:
2111:
758:Reboxetine is contraindicated in narrow-angle
10268:Serotonin–norepinephrine reuptake inhibitors:
10052:
9544:Serotonin–norepinephrine reuptake inhibitors:
9372:Selective norepinephrine reuptake inhibitors:
8665:
8639:Acetylcholine metabolism/transport modulators
7553:
7180:
6069:
3217:
2699:. West Sussex: Wiley-Blackwell. p. 588.
2244:Attention Deficit and Hyperactivity Disorders
927:
9458:Norepinephrine–dopamine reuptake inhibitors:
8689:
8634:Muscarinic acetylcholine receptor modulators
2198:
2196:
2075:
2073:
1770:
1768:
964:
687:
7514:Serotonin-norepinephrine reuptake inhibitor
7100:
6917:
6857:
6363:Tooltip Serotonin modulator and stimulators
3077:
3075:
2690:
2688:
2506:The Cochrane Database of Systematic Reviews
2236:
2234:
2108:
2031:
2029:
1836:"Reboxetine: benefit-risk balance reviewed"
1635:
1610:. Pfizer Australia Pty Ltd. 17 October 2012
1244:. Thus, four stereoisomers may exist, the (
9358:Tooltip Norepinephrine reuptake inhibitors
8672:
8658:
7560:
7546:
7520:Norepinephrine-dopamine reuptake inhibitor
7194:
7187:
7173:
6231:Tooltip Norepinephrine reuptake inhibitors
6083:
6076:
6062:
3224:
3210:
2813:Psychoactive Drug Screening Program (PDSP)
2151:
2149:
1228:. The primary metabolite of reboxetine is
1193:, a characteristic it shares with the NRI
406:
7585:Tooltip Nicotinic acetylcholine receptors
3151:
3128:"The promises and pitfalls of reboxetine"
3045:
3009:
2915:
2840:Brunton L, Chabner B, Knollman B (2010).
2641:
2525:
2431:
2287:International Clinical Psychopharmacology
2193:
2070:
2053:
1886:
1854:
1765:
1748:
1631:
1629:
1627:
1625:
1122:Tooltip Muscarinic acetylcholine receptor
434:
426:
10807:Tooltip Vesicular monoamine transporters
10082:Selective serotonin reuptake inhibitors:
8128:Candocuronium iodide (chandonium iodide)
7439:Attention deficit hyperactivity disorder
6958:
3072:
2864:
2685:
2231:
2026:
1137:Tooltip Nicotinic acetylcholine receptor
846:-desethylation is markedly inhibited by
725:Attention deficit hyperactivity disorder
669:attention deficit hyperactivity disorder
2799:
2795:
2793:
2791:
2146:
386:
14:
11020:
8008:Tooltip negative allosteric modulators
7604:Tooltip positive allosteric modulators
7508:Selective serotonin reuptake inhibitor
3062:"It's official: Pfizer buys Pharmacia"
3008:First publication per prior citation:
2665:
2663:
2661:
2370:
1830:
1828:
1622:
1553:
1334:
196:
10068:Tooltip Serotonin reuptake inhibitors
8653:
7541:
7168:
7053:
6957:
6728:
6487:
6100:
6057:
3205:
3174:
3047:10.1093/oxfordjournals.annonc.a058508
3030:"Farmitalia bought by Kabi Pharmacia"
2835:
2833:
2495:
2493:
1718:
1716:
1714:
1595:
1593:
1591:
1589:
1587:
1585:
1583:
579:CCOC1=C(C=CC=C1)O(2OCCNC2)C3=CC=CC=C3
474:
209:
8705:Tooltip Dopamine reuptake inhibitors
3125:
3081:
2788:
2695:Taylor D, Paton C, Shitij K (2012).
1669:
1667:
753:
143:
7450:Hypokalemic sensory overstimulation
6669:Tooltip Tetracyclic antidepressants
2858:
2658:
2578:
1825:
1200:
902:
454:
357:
24:
11053:Norepinephrine reuptake inhibitors
10402:Didesmethylsibutramine (BTS-54505)
9678:Didesmethylsibutramine (BTS-54505)
9347:Tooltip Norepinephrine transporter
9108:Didesmethylsibutramine (BTS-54505)
3197:Reboxetine: A Novel Antidepressant
3144:10.1111/j.1527-3458.2003.tb00258.x
2830:
2585:Joint Formulary Committee (2013).
2490:
2464:The American Journal of Psychiatry
2132:10.1097/01.chi.0000155327.30017.8c
1913:The Journal of Clinical Psychiatry
1711:
1580:
1170:(NRI), with approximately 20-fold
951:Tooltip Norepinephrine transporter
784:
25:
11079:
8920:Etybenzatropine (ethybenztropine)
8213:Dimethyltubocurarine (metocurine)
7490:Norepinephrine reuptake inhibitor
7054:
6511:Tooltip Tricyclic antidepressants
3190:
1664:
1168:norepinephrine reuptake inhibitor
1166:Reboxetine is a fairly selective
715:
659:, although it has also been used
645:norepinephrine reuptake inhibitor
170:
97:
10392:Desmethylsibutramine (BTS-54354)
9668:Desmethylsibutramine (BTS-54354)
9098:Desmethylsibutramine (BTS-54354)
7569:Nicotinic acetylcholine receptor
4102:1-(4-Methylphenyl)-2-aminobutane
2588:British National Formulary (BNF)
2564:10.1016/j.jpsychires.2013.07.003
2299:10.1097/00004850-200015060-00006
1650:10.2165/00023210-199912010-00006
640:
508:
502:
79:
38:
11003:Monoamine metabolism modulators
8593:Meclofenoxate (centrophenoxine)
7918:Suxethonium (succinyldicholine)
7913:Suxamethonium (succinylcholine)
5021:2-Phenyl-3,6-dimethylmorpholine
4715:N,alpha-Diethylphenylethylamine
3168:
3119:
3094:
3054:
3022:
3002:
2959:
2883:
2727:Drug Metabolism and Disposition
2609:
2552:Journal of Psychiatric Research
2542:
2448:
2407:
2364:
2321:
2278:
1983:
1939:
1569:from the original on 2023-08-03
1158:
1141:
897:
833:
819:. The symptoms are as follows:
682:
604:Key:CBQGYUDMJHNJBX-RTBURBONSA-N
7212:Tooltip central nervous system
5616:Troparil (β-CPT, WIN 35,065-2)
4217:2-Amino-1,2-dihydronaphthalene
3231:
2518:10.1002/14651858.CD010219.pub2
1903:
1547:
1339:
511:
496:
183:
13:
1:
10983:Receptor/signaling modulators
10057:Tooltip Serotonin transporter
8681:Monoamine reuptake inhibitors
8629:Receptor/signaling modulators
8283:Hexamethonium (benzohexonium)
2953:10.1016/S0040-4020(01)96541-X
2867:Australian Medicines Handbook
2330:Journal of Psychopharmacology
1879:10.1016/S0140-6736(17)32802-7
1796:10.1016/S0140-6736(09)60046-5
1541:
1304:Reboxetine was discovered at
932:Tooltip Serotonin transporter
733:
192:(Other controlled substances)
11068:Wakefulness-promoting agents
9897:Tetracyclic antidepressants:
8694:Tooltip Dopamine transporter
6731:Monoamine oxidase inhibitors
1235:
969:Tooltip Dopamine transporter
655:for use in the treatment of
647:(NRI) class, marketed as an
635:, sold under the brand name
7:
10347:3,3-Diphenylcyclobutanamine
9623:3,3-Diphenylcyclobutanamine
8363:Methorphan (racemethorphan)
7693:Bephenium hydroxynaphthoate
7472:Dopamine reuptake inhibitor
6925:Tooltip Monoamine oxidase B
6865:Tooltip Monoamine oxidase A
6494:tetracyclic antidepressants
5725:3,3-Diphenylcyclobutanamine
5265:2-Diphenylmethylpyrrolidine
5152:3,4-Dichloromethylphenidate
5147:2-Methyl-3-phenylpiperidine
838:Because of its reliance on
810:
10:
11084:
11063:Potassium channel blockers
10987:Monoamine releasing agents
10545:Tricyclic antidepressants:
9821:Tricyclic antidepressants:
8890:Benzatropine (benztropine)
7743:Dimethylphenylpiperazinium
7484:Norepinephrine transporter
6402:Dextromethorphan/bupropion
4720:N,N-Dimethylphenethylamine
3082:Lowe D (17 January 2011).
2476:10.1176/appi.ajp.160.2.297
2342:10.1177/026988110401800314
1299:
1176:norepinephrine transporter
796:), fast heart beat, heart
762:, cardiovascular disease,
486:Chemical and physical data
11033:Drugs developed by Pfizer
10975:
10931:
10800:
10611:
10540:
10339:
10263:
10077:
10050:
9928:
9892:
9816:
9615:
9539:
9453:
9367:
9340:
9023:
8877:
8841:
8765:
8714:
8687:
8621:
8535:
7996:
7592:
7578:
7455:Monoamine releasing agent
7431:
7410:
7342:
7311:
7273:
7205:
7125:
7060:
7049:
6966:
6953:
6915:
6855:
6741:
6737:
6724:
6700:
6662:
6504:
6500:
6483:
6384:
6356:
6323:
6290:
6257:
6224:
6176:
6118:
6114:
6096:
6038:
5712:
5639:
5441:
5433:Phenylpiracetam hydrazide
5413:
5255:
5127:
5039:
4956:
4092:
4039:
3996:
3938:
3765:
3597:
3564:
3496:
3413:
3350:
3292:8-Cyclopentyltheophylline
3277:
3239:
3175:Staff (14 October 2010).
2634:10.1017/S1092852922000906
2385:10.1080/00365590500407803
2256:10.1007/s12402-010-0027-x
829:Changes in blood pressure
688:Major depressive disorder
612:
587:
567:
555:
533:
520:
490:
485:
465:
445:
417:
397:
377:
352:
324:
297:
292:
279:
266:
249:
239:
229:
221:
160:
155:
130:
111:
85:
72:
67:
62:)-(+)-reboxetine (bottom)
37:
10271:Atomoxetine (tomoxetine)
9547:Atomoxetine (tomoxetine)
8603:Phosphatidylethanolamine
7108:Rubidium chloride (RbCl)
3757:Phthalimidopropiophenone
3181:Genetic Engineering News
2159:Human Psychopharmacology
1992:Human Psychopharmacology
1565:(published 2023-04-04).
10649:mepyramine (pyrilamine)
8383:Morphanol (racemorphan)
8323:Laudexium (laudolissin)
7733:Desformylflustrabromine
7227:Mixed amphetamine salts
6971:Atypical antipsychotics
5167:4-Methylmethylphenidate
5162:4-Fluoromethylphenidate
4271:β-Phenylmethamphetamine
4227:5-(2-Aminopropyl)indole
4162:4-Fluoromethamphetamine
4117:2-Fluoromethamphetamine
3722:Methylenedioxycathinone
2896:Neuropsychopharmacology
2766:10.1124/jpet.102.046532
1563:Diário Oficial da União
52:)-(–)-reboxetine (top),
27:NRI antidepressant drug
10923:Vanoxerine (GBR-12909)
10770:pethidine (meperidine)
10025:pethidine (meperidine)
8813:Pethidine (meperidine)
5491:Dichloropane (RTI-111)
4296:3-Benzhydrylmorpholine
4266:β-Methylphenethylamine
4142:3-Fluoroethamphetamine
4127:2-Phenyl-3-aminobutane
2865:Rossi, S, ed. (2013).
2433:10.1093/sleep/24.3.282
1608:TGA eBusiness Services
288:(78%; 9–10% unchanged)
11048:Nicotinic antagonists
11007:Monoamine neurotoxins
10573:Dosulepin (dothiepin)
10120:Didesmethylcitalopram
9849:Dosulepin (dothiepin)
9526:Serdexmethylphenidate
8828:Serdexmethylphenidate
8588:Glycerophosphocholine
7502:Serotonin transporter
7260:Serdexmethylphenidate
5606:Salicylmethylecgonine
5242:Serdexmethylphenidate
4966:3-Fluorophenmetrazine
4665:Dextromethamphetamine
4611:MDMA (midomafetamine)
4197:a-Ethylphenethylamine
3607:3-Fluoromethcathinone
3279:Adenosine antagonists
2671:"Edronax 4mg Tablets"
2217:10.1089/cap.2006.0145
2094:10.1089/cap.2006.0034
1961:10.1055/s-2004-832593
1306:Farmitalia-Carlo Erba
1180:serotonin transporter
854:. It weakly inhibits
677:continued to increase
10898:Methoxytetrabenazine
10863:Dihydrotetrabenazine
10677:Arylcyclohexylamines
9972:Arylcyclohexylamines
9123:Dizocilpine (MK-801)
9077:Chaenomeles speciosa
8778:Benocyclidine (BTCP)
8583:Dimethylethanolamine
8448:Rapacuronium bromide
8428:Pipecuronium bromide
8268:Gantacurium chloride
8228:Dizocilpine (MK-801)
7813:MEM-63,908 (RG-3487)
7763:Ethoxysebacylcholine
7466:Dopamine transporter
7411:Miscellaneous/others
7092:Hypericum perforatum
6960:Adjunctive therapies
5940:Naphthylaminopropane
5451:4-fluorotropacocaine
4537:5-Iodo-2-aminoindane
4532:4-Hydroxyamphetamine
4369:Dimethoxyamphetamine
4147:3-Methoxyamphetamine
3498:Arylcyclohexylamines
3297:8-Phenyltheophylline
3287:8-Chlorotheophylline
3040:(5): 345. May 1993.
1925:10.4088/JCP.v63n0107
1873:(10128): 1357–1366.
1323:In 2010, the German
1184:dopamine transporter
10522:Threohydrobupropion
10387:Desmethylsertraline
10115:Desmethylcitalopram
9798:Threohydrobupropion
9663:Desmethylsertraline
9318:Threohydrobupropion
9093:Desmethylsertraline
8598:Phosphatidylcholine
8483:Threohydrobupropion
8468:Stercuronium iodide
8403:Pancuronium bromide
7264:+dexmethylphenidate
6108:receptor modulators
6104:reuptake inhibitors
5026:Pseudophenmetrazine
4838:Phenylpropanolamine
4758:-Norpseudoephedrine
4725:Naphthylamphetamine
4669:Levomethamphetamine
4596:MDA (tenamfetamine)
4438:Ethylnorepinephrine
4374:Dimethylamphetamine
4157:4-Fluoroamphetamine
4152:3-Methylamphetamine
4137:3-Fluoroamphetamine
4112:2-Fluoroamphetamine
3385:Levopropylhexedrine
2908:10.1038/npp.2010.27
1676:Reboxetine Mesilate
1335:Society and culture
1240:Reboxetine has two
909:
643:, is a drug of the
205:(Prescription only)
179:(Prescription only)
34:
11038:Italian inventions
10762:dextropropoxyphene
8788:Dexmethylphenidate
8518:Vecuronium bromide
8458:Rocuronium bromide
8368:Methyllycaconitine
8293:Hydroxynorketamine
8188:Dextropropoxyphene
8173:Dehydronorketamine
8163:Dacuronium bromide
7255:Dexmethylphenidate
7152:Never to phase III
5216:Dexmethylphenidate
5202:Isopropylphenidate
5157:4-Benzylpiperidine
5142:2-Benzylpiperidine
4547:Indanylamphetamine
3642:4-Methylpentedrone
3627:4-Methylbuphedrone
3034:Annals of Oncology
2980:10.1007/bf03189965
1949:Pharmacopsychiatry
1840:Drug Safety Update
907:
744:nocturnal enuresis
214: Not approved
30:
11015:
11014:
11010:
10796:
10795:
10071:
10046:
10045:
9491:Levophacetoperane
9361:
9336:
9335:
9198:Levophacetoperane
8773:4-Fluoropethidine
8708:
8647:
8646:
8608:Phosphorylcholine
8546:
8531:
8530:
8328:Levacetylmethadol
8208:Dihydrochandonium
8088:sodium thiopental
7758:Ethanol (alcohol)
7535:
7534:
7235:Dextroamphetamine
7199:pharmacotherapies
7162:
7161:
7121:
7120:
7094:(St. John's Wort)
7045:
7044:
7010:lithium carbonate
6949:
6948:
6945:
6944:
6720:
6719:
6716:
6715:
6529:Amitriptylinoxide
6479:
6478:
6475:
6474:
6051:
6050:
5990:Rubidium chloride
5461:Altropane (IACFT)
5375:Indapyrophenidone
5197:Methylnaphthidate
4958:Phenylmorpholines
4878:Propylamphetamine
4757:
4569:
4358:
4246:Dextroamphetamine
3737:N-Ethylbuphedrone
3677:Dimethylcathinone
3632:4-Methylcathinone
3390:Methylhexaneamine
2876:978-0-9805790-9-3
2851:978-0-07-162442-8
2706:978-0-470-97948-8
2602:978-0-85711-084-8
1741:10.1136/bmj.c4737
1537:
1525:
1513:
1501:
1477:
1465:
1453:
1357:
1164:
1163:
802:urinary retention
772:urinary retention
754:Contraindications
630:
629:
546:Interactive image
213:
200:
187:
174:
101:
16:(Redirected from
11075:
10977:
10964:Antagonist-like:
10858:Deutetrabenazine
10808:
10804:
10748:MIN-117 (WF-516)
10713:Dextromethorphan
10085:6-Nitroquipazine
10075:
10074:
10069:
10065:
10060:
10058:
10054:
9481:Hydroxybupropion
9365:
9364:
9359:
9355:
9350:
9348:
9344:
9238:MIN-117 (WF-516)
9178:Hydroxybupropion
9118:Diphenylpyraline
8849:Diphenylprolinol
8712:
8711:
8706:
8702:
8697:
8695:
8691:
8674:
8667:
8660:
8651:
8650:
8540:
8478:Thiocolchicoside
8288:Hydroxybupropion
8183:Dextromethorphan
8055:Allopregnanolone
8009:
8005:
7908:Suberyldicholine
7618:6-Chloronicotine
7605:
7601:
7590:
7589:
7586:
7582:
7562:
7555:
7548:
7539:
7538:
7432:Related articles
7278:
7239:Lisdexamfetamine
7213:
7209:
7198:
7189:
7182:
7175:
7166:
7165:
7102:
7068:
7051:
7050:
7024:triiodothyronine
7020:Thyroid hormones
6955:
6954:
6926:
6922:
6866:
6862:
6807:Phenoxypropazine
6739:
6738:
6726:
6725:
6670:
6666:
6512:
6508:
6502:
6501:
6485:
6484:
6364:
6360:
6331:
6327:
6298:
6294:
6265:
6261:
6232:
6228:
6184:
6180:
6126:
6122:
6116:
6115:
6098:
6097:
6078:
6071:
6064:
6055:
6054:
5471:CFT (WIN 35,428)
5456:4'-Fluorococaine
5320:Diphenylprolinol
5187:Ethylnaphthidate
5182:Diphenylpyraline
4818:Phenpromethamine
4755:
4690:Methoxyphenamine
4680:Methoxyphenamine
4581:Lisdexamfetamine
4567:
4481:Levofenfluramine
4356:
4316:Chlorphentermine
4049:4-Methylaminorex
3742:N-Ethylhexedrone
3226:
3219:
3212:
3203:
3202:
3185:
3184:
3172:
3166:
3165:
3155:
3132:CNS Drug Reviews
3126:Page ME (2003).
3123:
3117:
3116:
3114:
3112:
3098:
3092:
3091:
3079:
3070:
3069:
3068:. 16 April 2003.
3058:
3052:
3051:
3049:
3026:
3020:
3019:
3006:
3000:
2999:
2963:
2957:
2956:
2947:(1): 1393–1399.
2936:
2930:
2929:
2919:
2887:
2881:
2880:
2862:
2856:
2855:
2837:
2828:
2827:
2825:
2824:
2797:
2786:
2785:
2749:
2743:
2742:
2722:
2711:
2710:
2692:
2683:
2682:
2680:
2678:
2667:
2656:
2655:
2645:
2613:
2607:
2606:
2582:
2576:
2575:
2546:
2540:
2539:
2529:
2497:
2488:
2487:
2461:
2452:
2446:
2445:
2435:
2411:
2405:
2404:
2368:
2362:
2361:
2325:
2319:
2318:
2282:
2276:
2275:
2238:
2229:
2228:
2200:
2191:
2190:
2171:10.1002/hup.1158
2153:
2144:
2143:
2115:
2106:
2105:
2077:
2068:
2067:
2057:
2033:
2024:
2023:
1987:
1981:
1980:
1943:
1937:
1936:
1907:
1901:
1900:
1890:
1858:
1852:
1851:
1849:
1847:
1832:
1823:
1822:
1820:
1814:. Archived from
1790:(9665): 746–58.
1781:
1772:
1763:
1762:
1752:
1720:
1709:
1708:
1702:
1698:
1696:
1688:
1686:
1684:
1671:
1662:
1661:
1633:
1620:
1619:
1617:
1615:
1605:
1597:
1578:
1577:
1575:
1574:
1551:
1531:
1519:
1507:
1483:
1471:
1459:
1363:
1351:
1201:Pharmacokinetics
1160:
1155:
1151:
1143:
1138:
1134:
1123:
1119:
970:
966:
952:
948:
933:
929:
910:
906:
903:Pharmacodynamics
768:bipolar disorder
678:
657:major depression
626:
625:
618:
548:
528:
513:
510:
504:
498:
478:
458:
438:
430:
410:
390:
370:
360:
359:
345:
337:
271:
211:
208:
198:
195:
185:
182:
172:
169:
147:
99:
96:
42:
35:
33:
29:
21:
11083:
11082:
11078:
11077:
11076:
11074:
11073:
11072:
11028:Antidepressants
11018:
11017:
11016:
11011:
10971:
10949:DAT modulators:
10927:
10828:methamphetamine
10806:
10792:
10703:Cyclobenzaprine
10645:diphenhydramine
10633:brompheniramine
10607:
10536:
10335:
10301:Levomilnacipran
10259:
10067:
10059:
10056:
10042:
9940:brompheniramine
9924:
9888:
9812:
9611:
9572:Levomilnacipran
9535:
9506:Methylphenidate
9449:
9357:
9349:
9346:
9332:
9019:
8873:
8837:
8808:Methylphenidate
8783:Desoxypipradrol
8761:
8704:
8696:
8693:
8683:
8678:
8648:
8643:
8617:
8539:
8527:
8133:Chlorisondamine
8007:
8000:
7992:
7603:
7596:
7584:
7574:
7566:
7536:
7531:
7427:
7406:
7344:Antidepressants
7338:
7319:
7316:
7307:
7275:
7269:
7250:Methylphenidate
7245:Methamphetamine
7231:Levoamphetamine
7211:
7201:
7193:
7163:
7158:
7157:
7142:Clinical trials
7117:
7056:
7041:
7037:
7029:
7014:lithium citrate
6962:
6941:
6924:
6921:
6911:
6864:
6861:
6851:
6827:Tranylcypromine
6733:
6712:
6696:
6668:
6658:
6510:
6496:
6471:
6380:
6362:
6352:
6329:
6319:
6296:
6286:
6263:
6253:
6230:
6220:
6201:Levomilnacipran
6182:
6172:
6124:
6110:
6092:
6085:Antidepressants
6082:
6052:
6047:
6034:
5935:Methiopropamine
5708:
5635:
5561:RTI-121 (IPCIT)
5437:
5428:Phenylpiracetam
5409:
5251:
5237:Propylphenidate
5212:Methylphenidate
5172:Desoxypipradrol
5123:
5035:
5011:Phendimetrazine
4952:
4928:Tranylcypromine
4883:Pseudoephedrine
4750:Normetanephrine
4745:Norfenfluramine
4661:Methamphetamine
4477:Dexfenfluramine
4250:Levoamphetamine
4232:2-Aminotetralin
4094:Phenethylamines
4088:
4035:
3992:
3934:
3761:
3702:Isoethcathinone
3593:
3560:
3492:
3409:
3400:Propylhexedrine
3346:
3273:
3235:
3230:
3193:
3188:
3173:
3169:
3124:
3120:
3110:
3108:
3100:
3099:
3095:
3088:In the pipeline
3080:
3073:
3060:
3059:
3055:
3028:
3027:
3023:
3007:
3003:
2964:
2960:
2937:
2933:
2888:
2884:
2877:
2863:
2859:
2852:
2838:
2831:
2822:
2820:
2808:
2798:
2789:
2750:
2746:
2733:(11): 1334–40.
2723:
2714:
2707:
2693:
2686:
2676:
2674:
2669:
2668:
2659:
2614:
2610:
2603:
2583:
2579:
2558:(11): 1557–63.
2547:
2543:
2512:(1): CD010219.
2498:
2491:
2459:
2453:
2449:
2412:
2408:
2369:
2365:
2326:
2322:
2283:
2279:
2239:
2232:
2201:
2194:
2154:
2147:
2116:
2109:
2078:
2071:
2034:
2027:
2004:10.1002/hup.421
1988:
1984:
1944:
1940:
1908:
1904:
1859:
1855:
1845:
1843:
1834:
1833:
1826:
1818:
1779:
1773:
1766:
1721:
1712:
1700:
1699:
1690:
1689:
1682:
1680:
1673:
1672:
1665:
1634:
1623:
1613:
1611:
1603:
1599:
1598:
1581:
1572:
1570:
1552:
1548:
1544:
1342:
1337:
1302:
1238:
1203:
1178:(NET) over the
1153:
1136:
1121:
1104:
1090:
1077:
1064:
1051:
1035:
1021:
1008:
995:
982:
968:
950:
931:
919:
905:
900:
836:
813:
787:
785:Adverse effects
756:
740:bulimia nervosa
736:
727:
718:
690:
685:
676:
621:
619:
616:(what is this?)
613:
608:
605:
600:
595:
594:
583:
580:
575:
574:
551:
526:
516:
507:
501:
481:
461:
441:
433:Mesylate:
413:
393:
373:
356:
348:
340:Mesylate:
320:
317:
305:
304:
269:
241:Protein binding
231:Bioavailability
223:Pharmacokinetic
217:
151:
114:
107:
88:
63:
53:
28:
23:
22:
15:
12:
11:
5:
11081:
11071:
11070:
11065:
11060:
11055:
11050:
11045:
11040:
11035:
11030:
11013:
11012:
10976:
10973:
10972:
10970:
10969:
10957:
10945:
10944:
10939:DAT enhancers:
10935:
10933:
10929:
10928:
10926:
10925:
10920:
10915:
10910:
10905:
10900:
10895:
10890:
10885:
10880:
10875:
10870:
10865:
10860:
10855:
10850:
10845:
10840:
10835:
10817:
10811:
10809:
10798:
10797:
10794:
10793:
10791:
10790:
10785:
10755:
10750:
10745:
10740:
10735:
10730:
10725:
10720:
10715:
10710:
10705:
10700:
10674:
10663:Antipsychotics
10660:
10657:tripelennamine
10641:dimenhydrinate
10637:chlorphenamine
10629:Antihistamines
10626:
10621:
10612:
10609:
10608:
10606:
10605:
10600:
10595:
10590:
10585:
10580:
10575:
10570:
10565:
10563:Cyanodothiepin
10560:
10555:
10550:
10541:
10538:
10537:
10535:
10534:
10524:
10519:
10514:
10509:
10504:
10499:
10494:
10489:
10484:
10479:
10474:
10469:
10464:
10459:
10454:
10449:
10444:
10439:
10434:
10429:
10424:
10419:
10414:
10409:
10404:
10399:
10394:
10389:
10384:
10379:
10374:
10369:
10364:
10359:
10354:
10349:
10340:
10337:
10336:
10334:
10333:
10328:
10323:
10318:
10313:
10308:
10303:
10298:
10293:
10288:
10286:Desvenlafaxine
10283:
10278:
10273:
10264:
10261:
10260:
10258:
10257:
10252:
10247:
10242:
10237:
10232:
10227:
10222:
10217:
10212:
10203:
10202:
10197:
10192:
10187:
10182:
10177:
10172:
10167:
10162:
10157:
10152:
10147:
10142:
10137:
10132:
10127:
10122:
10117:
10112:
10107:
10102:
10097:
10092:
10087:
10078:
10072:
10048:
10047:
10044:
10043:
10041:
10040:
10010:
10005:
10000:
9993:
9988:
9983:
9969:
9958:Antipsychotics
9955:
9952:tripelennamine
9944:chlorphenamine
9936:Antihistamines
9929:
9926:
9925:
9923:
9922:
9917:
9912:
9907:
9902:
9893:
9890:
9889:
9887:
9886:
9881:
9876:
9871:
9866:
9861:
9856:
9851:
9846:
9841:
9836:
9831:
9826:
9817:
9814:
9813:
9811:
9810:
9800:
9795:
9790:
9785:
9780:
9775:
9770:
9765:
9760:
9755:
9750:
9745:
9740:
9735:
9730:
9725:
9720:
9715:
9710:
9705:
9700:
9695:
9690:
9685:
9680:
9675:
9670:
9665:
9660:
9655:
9650:
9645:
9640:
9635:
9630:
9625:
9616:
9613:
9612:
9610:
9609:
9604:
9599:
9594:
9589:
9584:
9579:
9574:
9569:
9564:
9559:
9557:Desvenlafaxine
9554:
9549:
9540:
9537:
9536:
9534:
9533:
9528:
9523:
9518:
9513:
9508:
9503:
9498:
9493:
9488:
9483:
9478:
9473:
9468:
9463:
9454:
9451:
9450:
9448:
9447:
9442:
9437:
9432:
9427:
9422:
9417:
9412:
9407:
9402:
9397:
9392:
9387:
9382:
9377:
9368:
9362:
9338:
9337:
9334:
9333:
9331:
9330:
9325:
9323:Tripelennamine
9320:
9315:
9310:
9305:
9300:
9295:
9290:
9285:
9280:
9275:
9270:
9265:
9260:
9255:
9250:
9245:
9240:
9235:
9230:
9225:
9220:
9215:
9210:
9205:
9200:
9195:
9190:
9185:
9180:
9175:
9170:
9165:
9160:
9155:
9150:
9145:
9140:
9135:
9130:
9125:
9120:
9115:
9110:
9105:
9100:
9095:
9090:
9085:
9080:
9073:
9068:
9063:
9058:
9053:
9048:
9046:Amfonelic acid
9043:
9038:
9033:
9024:
9021:
9020:
9018:
9017:
9012:
9007:
9002:
8997:
8992:
8987:
8982:
8977:
8972:
8967:
8962:
8957:
8952:
8947:
8942:
8937:
8932:
8927:
8922:
8917:
8912:
8907:
8902:
8897:
8892:
8887:
8878:
8875:
8874:
8872:
8871:
8866:
8861:
8856:
8851:
8842:
8839:
8838:
8836:
8835:
8830:
8825:
8820:
8815:
8810:
8805:
8800:
8798:Ethylphenidate
8795:
8790:
8785:
8780:
8775:
8766:
8763:
8762:
8760:
8759:
8754:
8749:
8744:
8739:
8734:
8729:
8724:
8715:
8709:
8685:
8684:
8677:
8676:
8669:
8662:
8654:
8645:
8644:
8642:
8641:
8636:
8631:
8626:
8622:
8619:
8618:
8616:
8615:
8610:
8605:
8600:
8595:
8590:
8585:
8580:
8575:
8570:
8560:
8555:
8549:
8547:
8533:
8532:
8529:
8528:
8526:
8525:
8520:
8515:
8510:
8505:
8500:
8495:
8490:
8485:
8480:
8475:
8470:
8465:
8460:
8455:
8450:
8445:
8440:
8435:
8430:
8425:
8420:
8415:
8410:
8405:
8400:
8395:
8390:
8385:
8380:
8375:
8370:
8365:
8360:
8355:
8350:
8345:
8340:
8335:
8330:
8325:
8320:
8315:
8313:Kynurenic acid
8310:
8305:
8300:
8295:
8290:
8285:
8280:
8275:
8270:
8265:
8260:
8255:
8250:
8245:
8240:
8235:
8230:
8225:
8220:
8215:
8210:
8205:
8200:
8195:
8190:
8185:
8180:
8175:
8170:
8165:
8160:
8155:
8150:
8145:
8140:
8135:
8130:
8125:
8120:
8115:
8110:
8107:κ-bungarotoxin
8103:α-bungarotoxin
8096:
8091:
8077:
8072:
8067:
8062:
8057:
8052:
8047:
8042:
8041:, many others)
8031:α-bungarotoxin
8024:
8019:
8013:
8011:
7994:
7993:
7991:
7990:
7985:
7980:
7975:
7970:
7965:
7963:Tribendimidine
7960:
7955:
7950:
7945:
7940:
7935:
7930:
7925:
7920:
7915:
7910:
7905:
7900:
7895:
7890:
7888:Sebacylcholine
7885:
7880:
7875:
7870:
7865:
7860:
7855:
7850:
7845:
7840:
7835:
7830:
7820:
7815:
7810:
7805:
7800:
7795:
7790:
7785:
7780:
7775:
7770:
7765:
7760:
7755:
7750:
7745:
7740:
7735:
7730:
7725:
7720:
7715:
7710:
7705:
7703:Butyrylcholine
7700:
7695:
7690:
7685:
7680:
7675:
7670:
7665:
7660:
7655:
7650:
7645:
7640:
7635:
7630:
7625:
7620:
7615:
7609:
7607:
7587:
7576:
7575:
7565:
7564:
7557:
7550:
7542:
7533:
7532:
7530:
7529:
7523:
7517:
7511:
7505:
7499:
7493:
7487:
7481:
7478:Norepinephrine
7475:
7469:
7463:
7457:
7452:
7447:
7442:
7435:
7433:
7429:
7428:
7426:
7425:
7420:
7414:
7412:
7408:
7407:
7405:
7404:
7399:
7394:
7389:
7384:
7379:
7374:
7369:
7364:
7359:
7354:
7348:
7346:
7340:
7339:
7337:
7336:
7331:
7325:
7323:
7314:
7309:
7308:
7306:
7305:
7300:
7295:
7290:
7284:
7282:
7271:
7270:
7268:
7267:
7257:
7252:
7247:
7242:
7219:
7217:
7203:
7202:
7192:
7191:
7184:
7177:
7169:
7160:
7159:
7156:
7155:
7154:
7153:
7150:
7139:
7133:
7127:
7126:
7123:
7122:
7119:
7118:
7116:
7115:
7110:
7105:
7096:
7088:
7071:
7065:Ademetionine (
7061:
7058:
7057:
7047:
7046:
7043:
7042:
7040:
7039:
7035:
7027:
7017:
7003:
6998:
6967:
6964:
6963:
6951:
6950:
6947:
6946:
6943:
6942:
6940:
6939:
6930:
6928:
6919:
6913:
6912:
6910:
6909:
6904:
6899:
6894:
6889:
6884:
6879:
6870:
6868:
6859:
6853:
6852:
6850:
6849:
6840:
6839:
6830:
6829:
6824:
6819:
6814:
6809:
6804:
6799:
6794:
6789:
6784:
6779:
6774:
6769:
6764:
6759:
6754:
6745:
6743:
6735:
6734:
6722:
6721:
6718:
6717:
6714:
6713:
6711:
6710:
6704:
6702:
6698:
6697:
6695:
6694:
6689:
6684:
6679:
6673:
6671:
6660:
6659:
6657:
6656:
6651:
6646:
6641:
6636:
6631:
6626:
6621:
6616:
6611:
6606:
6601:
6596:
6591:
6586:
6584:Imipraminoxide
6581:
6576:
6571:
6566:
6561:
6556:
6551:
6546:
6541:
6536:
6531:
6526:
6521:
6515:
6513:
6498:
6497:
6481:
6480:
6477:
6476:
6473:
6472:
6470:
6469:
6464:
6459:
6454:
6449:
6444:
6439:
6434:
6429:
6424:
6419:
6414:
6409:
6404:
6399:
6394:
6388:
6386:
6382:
6381:
6379:
6378:
6373:
6367:
6365:
6354:
6353:
6351:
6350:
6345:
6340:
6334:
6332:
6321:
6320:
6318:
6317:
6312:
6307:
6301:
6299:
6288:
6287:
6285:
6284:
6279:
6274:
6268:
6266:
6255:
6254:
6252:
6251:
6246:
6241:
6235:
6233:
6222:
6221:
6219:
6218:
6213:
6208:
6203:
6198:
6193:
6191:Desvenlafaxine
6187:
6185:
6174:
6173:
6171:
6170:
6165:
6160:
6155:
6150:
6145:
6140:
6135:
6129:
6127:
6112:
6111:
6094:
6093:
6081:
6080:
6073:
6066:
6058:
6049:
6048:
6039:
6036:
6035:
6033:
6032:
6027:
6022:
6017:
6012:
6007:
6002:
5997:
5992:
5987:
5982:
5977:
5972:
5967:
5962:
5957:
5952:
5947:
5942:
5937:
5932:
5930:Methastyridone
5927:
5925:Methamnetamine
5922:
5917:
5912:
5907:
5902:
5897:
5892:
5887:
5882:
5877:
5872:
5867:
5862:
5857:
5852:
5847:
5842:
5837:
5832:
5827:
5822:
5817:
5812:
5807:
5802:
5797:
5792:
5787:
5782:
5777:
5772:
5767:
5762:
5757:
5752:
5747:
5742:
5737:
5732:
5730:Amfonelic acid
5727:
5722:
5716:
5714:
5710:
5709:
5707:
5706:
5701:
5696:
5691:
5686:
5681:
5676:
5671:
5666:
5661:
5656:
5651:
5645:
5643:
5637:
5636:
5634:
5633:
5628:
5623:
5618:
5613:
5608:
5603:
5598:
5593:
5588:
5583:
5578:
5573:
5568:
5563:
5558:
5553:
5548:
5543:
5538:
5533:
5528:
5523:
5518:
5513:
5508:
5503:
5498:
5493:
5488:
5483:
5478:
5476:β-CIT (RTI-55)
5473:
5468:
5463:
5458:
5453:
5447:
5445:
5439:
5438:
5436:
5435:
5430:
5425:
5419:
5417:
5411:
5410:
5408:
5407:
5402:
5397:
5392:
5387:
5382:
5377:
5372:
5367:
5362:
5357:
5352:
5347:
5342:
5337:
5332:
5327:
5322:
5317:
5312:
5307:
5302:
5297:
5292:
5287:
5282:
5277:
5272:
5267:
5261:
5259:
5253:
5252:
5250:
5249:
5244:
5239:
5234:
5229:
5224:
5219:
5209:
5204:
5199:
5194:
5192:Ethylphenidate
5189:
5184:
5179:
5174:
5169:
5164:
5159:
5154:
5149:
5144:
5139:
5133:
5131:
5125:
5124:
5122:
5121:
5116:
5111:
5106:
5101:
5096:
5091:
5086:
5081:
5076:
5071:
5066:
5061:
5056:
5051:
5045:
5043:
5037:
5036:
5034:
5033:
5028:
5023:
5018:
5013:
5008:
5003:
4998:
4993:
4988:
4983:
4978:
4973:
4968:
4962:
4960:
4954:
4953:
4951:
4950:
4945:
4940:
4935:
4930:
4925:
4920:
4915:
4910:
4905:
4900:
4897:Levosalbutamol
4890:
4885:
4880:
4875:
4870:
4865:
4860:
4855:
4850:
4845:
4840:
4835:
4830:
4825:
4820:
4815:
4810:
4805:
4800:
4795:
4790:
4785:
4780:
4775:
4770:
4765:
4760:
4752:
4747:
4742:
4737:
4735:Norepinephrine
4732:
4727:
4722:
4717:
4712:
4707:
4702:
4697:
4692:
4687:
4682:
4677:
4672:
4658:
4653:
4648:
4643:
4638:
4633:
4628:
4623:
4618:
4613:
4608:
4603:
4598:
4593:
4588:
4583:
4578:
4573:
4564:
4559:
4554:
4549:
4544:
4539:
4534:
4529:
4524:
4519:
4514:
4509:
4504:
4499:
4494:
4489:
4484:
4470:
4465:
4460:
4455:
4450:
4445:
4443:Etilamfetamine
4440:
4435:
4430:
4425:
4420:
4415:
4410:
4405:
4400:
4395:
4381:
4376:
4371:
4366:
4361:
4353:
4348:
4343:
4338:
4333:
4328:
4323:
4318:
4313:
4308:
4303:
4298:
4293:
4288:
4283:
4278:
4273:
4268:
4263:
4258:
4253:
4239:
4234:
4229:
4224:
4219:
4214:
4209:
4204:
4199:
4194:
4189:
4184:
4179:
4174:
4169:
4164:
4159:
4154:
4149:
4144:
4139:
4134:
4129:
4124:
4119:
4114:
4109:
4104:
4098:
4096:
4090:
4089:
4087:
4086:
4081:
4076:
4071:
4066:
4061:
4056:
4051:
4045:
4043:
4037:
4036:
4034:
4033:
4028:
4023:
4018:
4013:
4008:
4002:
4000:
3994:
3993:
3991:
3990:
3985:
3980:
3975:
3970:
3965:
3960:
3955:
3950:
3944:
3942:
3936:
3935:
3933:
3932:
3927:
3922:
3917:
3912:
3907:
3902:
3897:
3892:
3887:
3882:
3877:
3872:
3867:
3862:
3857:
3852:
3847:
3842:
3837:
3832:
3827:
3822:
3817:
3812:
3807:
3802:
3797:
3792:
3787:
3782:
3777:
3771:
3769:
3763:
3762:
3760:
3759:
3754:
3749:
3744:
3739:
3734:
3729:
3724:
3719:
3714:
3709:
3704:
3699:
3694:
3689:
3684:
3679:
3674:
3669:
3664:
3659:
3654:
3649:
3644:
3639:
3634:
3629:
3624:
3619:
3614:
3609:
3603:
3601:
3595:
3594:
3592:
3591:
3586:
3581:
3576:
3570:
3568:
3562:
3561:
3559:
3558:
3553:
3548:
3543:
3538:
3533:
3528:
3523:
3518:
3513:
3511:Dieticyclidine
3508:
3502:
3500:
3494:
3493:
3491:
3490:
3485:
3480:
3475:
3470:
3465:
3460:
3455:
3450:
3445:
3440:
3435:
3430:
3425:
3419:
3417:
3411:
3410:
3408:
3407:
3405:Tuaminoheptane
3402:
3397:
3392:
3387:
3382:
3377:
3372:
3367:
3362:
3360:Cyclopentamine
3356:
3354:
3348:
3347:
3345:
3344:
3339:
3334:
3329:
3324:
3322:Istradefylline
3319:
3314:
3309:
3304:
3299:
3294:
3289:
3283:
3281:
3275:
3274:
3272:
3271:
3266:
3261:
3256:
3251:
3245:
3243:
3237:
3236:
3229:
3228:
3221:
3214:
3206:
3200:
3199:
3192:
3191:External links
3189:
3187:
3186:
3167:
3118:
3093:
3071:
3053:
3021:
3012:Eur J Med Chem
3001:
2958:
2931:
2882:
2875:
2857:
2850:
2829:
2806:
2787:
2760:(1): 197–204.
2744:
2712:
2705:
2684:
2657:
2608:
2601:
2577:
2541:
2489:
2470:(2): 297–302.
2447:
2406:
2363:
2320:
2277:
2230:
2192:
2165:(7–8): 570–6.
2145:
2107:
2069:
2025:
1982:
1938:
1902:
1853:
1824:
1821:on 2013-09-29.
1764:
1710:
1663:
1621:
1579:
1557:(2023-03-31).
1545:
1543:
1540:
1539:
1538:
1526:
1514:
1502:
1478:
1466:
1454:
1358:
1341:
1338:
1336:
1333:
1301:
1298:
1296:)-(+)-isomer.
1242:chiral centers
1237:
1234:
1202:
1199:
1162:
1161:
1156:
1145:
1144:
1139:
1128:
1127:
1124:
1113:
1112:
1107:
1102:
1096:
1095:
1092:
1088:
1083:
1082:
1079:
1075:
1070:
1069:
1066:
1062:
1057:
1056:
1053:
1049:
1044:
1043:
1038:
1033:
1027:
1026:
1023:
1019:
1014:
1013:
1010:
1006:
1001:
1000:
997:
993:
988:
987:
984:
980:
975:
974:
971:
960:
959:
954:
941:
940:
935:
922:
921:
917:
914:
904:
901:
899:
896:
864:P-glycoprotein
835:
832:
831:
830:
827:
824:
812:
809:
786:
783:
755:
752:
735:
732:
726:
723:
717:
716:Panic disorder
714:
689:
686:
684:
681:
665:panic disorder
649:antidepressant
628:
627:
610:
609:
607:
606:
603:
601:
598:
590:
589:
588:
585:
584:
582:
581:
578:
570:
569:
568:
565:
564:
559:
553:
552:
550:
549:
541:
539:
531:
530:
524:
518:
517:
514:
505:
499:
494:
488:
487:
483:
482:
480:
479:
471:
469:
463:
462:
460:
459:
451:
449:
443:
442:
440:
439:
431:
423:
421:
415:
414:
412:
411:
403:
401:
395:
394:
392:
391:
383:
381:
375:
374:
372:
371:
363:
361:
350:
349:
347:
346:
338:
330:
328:
322:
321:
319:
318:
316:)-2-morpholine
308:
300:
299:
298:
295:
294:
290:
289:
283:
277:
276:
273:
264:
263:
253:
247:
246:
243:
237:
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227:
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218:
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215:
206:
193:
180:
166:
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157:
153:
152:
150:
149:
136:
134:
128:
127:
117:
115:administration
109:
108:
106:
105:
103:
93:
91:
83:
82:
76:
70:
69:
65:
64:
43:
26:
9:
6:
4:
3:
2:
11080:
11069:
11066:
11064:
11061:
11059:
11058:Phenol ethers
11056:
11054:
11051:
11049:
11046:
11044:
11041:
11039:
11036:
11034:
11031:
11029:
11026:
11025:
11023:
11009:
11008:
11004:
11000:
10999:Serotonergics
10996:
10995:Dopaminergics
10992:
10988:
10984:
10981:
10974:
10968:
10965:
10961:
10958:
10956:
10953:
10952:Agonist-like:
10950:
10947:
10946:
10943:
10940:
10937:
10936:
10934:
10930:
10924:
10921:
10919:
10916:
10914:
10913:Tetrabenazine
10911:
10909:
10906:
10904:
10901:
10899:
10896:
10894:
10891:
10889:
10886:
10884:
10881:
10879:
10876:
10874:
10871:
10869:
10866:
10864:
10861:
10859:
10856:
10854:
10851:
10849:
10846:
10844:
10841:
10839:
10836:
10833:
10829:
10825:
10821:
10818:
10816:
10813:
10812:
10810:
10805:
10799:
10789:
10786:
10783:
10779:
10775:
10771:
10767:
10763:
10759:
10756:
10754:
10751:
10749:
10746:
10744:
10741:
10739:
10736:
10734:
10731:
10729:
10726:
10724:
10721:
10719:
10716:
10714:
10711:
10709:
10706:
10704:
10701:
10698:
10697:phencyclidine
10694:
10693:methoxetamine
10690:
10686:
10682:
10678:
10675:
10672:
10668:
10664:
10661:
10658:
10654:
10650:
10646:
10642:
10638:
10634:
10630:
10627:
10625:
10622:
10620:
10617:
10614:
10613:
10610:
10604:
10603:Protriptyline
10601:
10599:
10596:
10594:
10593:Nortriptyline
10591:
10589:
10586:
10584:
10581:
10579:
10576:
10574:
10571:
10569:
10566:
10564:
10561:
10559:
10556:
10554:
10551:
10549:
10548:Amitriptyline
10546:
10543:
10542:
10539:
10532:
10528:
10525:
10523:
10520:
10518:
10515:
10513:
10512:Tedatioxetine
10510:
10508:
10505:
10503:
10500:
10498:
10495:
10493:
10490:
10488:
10485:
10483:
10480:
10478:
10475:
10473:
10470:
10468:
10465:
10463:
10460:
10458:
10455:
10453:
10450:
10448:
10445:
10443:
10440:
10438:
10435:
10433:
10430:
10428:
10425:
10423:
10420:
10418:
10415:
10413:
10410:
10408:
10405:
10403:
10400:
10398:
10395:
10393:
10390:
10388:
10385:
10383:
10380:
10378:
10375:
10373:
10372:Centanafadine
10370:
10368:
10365:
10363:
10360:
10358:
10355:
10353:
10350:
10348:
10345:
10342:
10341:
10338:
10332:
10329:
10327:
10324:
10322:
10319:
10317:
10316:N-Methyl-PPPA
10314:
10312:
10309:
10307:
10304:
10302:
10299:
10297:
10294:
10292:
10289:
10287:
10284:
10282:
10279:
10277:
10274:
10272:
10269:
10266:
10265:
10262:
10256:
10253:
10251:
10248:
10246:
10243:
10241:
10238:
10236:
10233:
10231:
10228:
10226:
10223:
10221:
10218:
10216:
10213:
10211:
10208:
10205:
10204:
10201:
10198:
10196:
10193:
10191:
10188:
10186:
10183:
10181:
10178:
10176:
10173:
10171:
10168:
10166:
10163:
10161:
10158:
10156:
10155:Norfluoxetine
10153:
10151:
10148:
10146:
10143:
10141:
10138:
10136:
10133:
10131:
10128:
10126:
10123:
10121:
10118:
10116:
10113:
10111:
10108:
10106:
10103:
10101:
10098:
10096:
10095:Centpropazine
10093:
10091:
10088:
10086:
10083:
10080:
10079:
10076:
10073:
10066:
10055:
10049:
10038:
10034:
10030:
10026:
10022:
10018:
10017:desmetramadol
10014:
10011:
10009:
10006:
10004:
10001:
9999:
9998:
9997:Ginkgo biloba
9994:
9992:
9989:
9987:
9984:
9981:
9980:phencyclidine
9977:
9973:
9970:
9967:
9963:
9959:
9956:
9953:
9949:
9945:
9941:
9937:
9934:
9931:
9930:
9927:
9921:
9918:
9916:
9913:
9911:
9908:
9906:
9903:
9901:
9898:
9895:
9894:
9891:
9885:
9882:
9880:
9879:Protriptyline
9877:
9875:
9874:Nortriptyline
9872:
9870:
9867:
9865:
9862:
9860:
9857:
9855:
9852:
9850:
9847:
9845:
9842:
9840:
9837:
9835:
9832:
9830:
9827:
9825:
9824:Amitriptyline
9822:
9819:
9818:
9815:
9808:
9804:
9801:
9799:
9796:
9794:
9791:
9789:
9788:Tedatioxetine
9786:
9784:
9781:
9779:
9776:
9774:
9771:
9769:
9766:
9764:
9761:
9759:
9756:
9754:
9751:
9749:
9746:
9744:
9741:
9739:
9736:
9734:
9731:
9729:
9726:
9724:
9721:
9719:
9716:
9714:
9711:
9709:
9706:
9704:
9701:
9699:
9696:
9694:
9691:
9689:
9686:
9684:
9681:
9679:
9676:
9674:
9671:
9669:
9666:
9664:
9661:
9659:
9656:
9654:
9651:
9649:
9648:Centanafadine
9646:
9644:
9641:
9639:
9636:
9634:
9631:
9629:
9626:
9624:
9621:
9618:
9617:
9614:
9608:
9605:
9603:
9600:
9598:
9595:
9593:
9590:
9588:
9587:N-Methyl-PPPA
9585:
9583:
9580:
9578:
9575:
9573:
9570:
9568:
9565:
9563:
9560:
9558:
9555:
9553:
9550:
9548:
9545:
9542:
9541:
9538:
9532:
9529:
9527:
9524:
9522:
9519:
9517:
9514:
9512:
9509:
9507:
9504:
9502:
9499:
9497:
9494:
9492:
9489:
9487:
9484:
9482:
9479:
9477:
9474:
9472:
9469:
9467:
9464:
9462:
9459:
9456:
9455:
9452:
9446:
9443:
9441:
9438:
9436:
9433:
9431:
9428:
9426:
9423:
9421:
9418:
9416:
9413:
9411:
9408:
9406:
9403:
9401:
9398:
9396:
9393:
9391:
9388:
9386:
9383:
9381:
9378:
9376:
9373:
9370:
9369:
9366:
9363:
9356:
9345:
9339:
9329:
9326:
9324:
9321:
9319:
9316:
9314:
9313:Tedatioxetine
9311:
9309:
9306:
9304:
9301:
9299:
9296:
9294:
9291:
9289:
9286:
9284:
9281:
9279:
9276:
9274:
9271:
9269:
9266:
9264:
9261:
9259:
9256:
9254:
9251:
9249:
9246:
9244:
9241:
9239:
9236:
9234:
9231:
9229:
9226:
9224:
9221:
9219:
9216:
9214:
9211:
9209:
9206:
9204:
9201:
9199:
9196:
9194:
9191:
9189:
9186:
9184:
9181:
9179:
9176:
9174:
9171:
9169:
9166:
9164:
9161:
9159:
9156:
9154:
9151:
9149:
9146:
9144:
9141:
9139:
9136:
9134:
9131:
9129:
9126:
9124:
9121:
9119:
9116:
9114:
9111:
9109:
9106:
9104:
9101:
9099:
9096:
9094:
9091:
9089:
9086:
9084:
9081:
9079:
9078:
9074:
9072:
9069:
9067:
9064:
9062:
9059:
9057:
9054:
9052:
9049:
9047:
9044:
9042:
9039:
9037:
9034:
9032:
9029:
9026:
9025:
9022:
9016:
9013:
9011:
9008:
9006:
9003:
9001:
8998:
8996:
8993:
8991:
8988:
8986:
8983:
8981:
8978:
8976:
8973:
8971:
8968:
8966:
8963:
8961:
8958:
8956:
8953:
8951:
8948:
8946:
8943:
8941:
8938:
8936:
8935:Ioflupane (I)
8933:
8931:
8928:
8926:
8923:
8921:
8918:
8916:
8913:
8911:
8908:
8906:
8903:
8901:
8898:
8896:
8893:
8891:
8888:
8886:
8883:
8880:
8879:
8876:
8870:
8867:
8865:
8862:
8860:
8857:
8855:
8852:
8850:
8847:
8846:Pyrrolidines:
8844:
8843:
8840:
8834:
8833:Tenocyclidine
8831:
8829:
8826:
8824:
8821:
8819:
8818:Phencyclidine
8816:
8814:
8811:
8809:
8806:
8804:
8801:
8799:
8796:
8794:
8791:
8789:
8786:
8784:
8781:
8779:
8776:
8774:
8771:
8768:
8767:
8764:
8758:
8755:
8753:
8750:
8748:
8745:
8743:
8740:
8738:
8735:
8733:
8730:
8728:
8725:
8723:
8720:
8717:
8716:
8713:
8710:
8703:
8692:
8686:
8682:
8675:
8670:
8668:
8663:
8661:
8656:
8655:
8652:
8640:
8637:
8635:
8632:
8630:
8627:
8624:
8623:
8620:
8614:
8611:
8609:
8606:
8604:
8601:
8599:
8596:
8594:
8591:
8589:
8586:
8584:
8581:
8579:
8576:
8574:
8571:
8568:
8564:
8561:
8559:
8556:
8554:
8551:
8550:
8548:
8544:
8538:
8534:
8524:
8521:
8519:
8516:
8514:
8511:
8509:
8506:
8504:
8501:
8499:
8496:
8494:
8491:
8489:
8486:
8484:
8481:
8479:
8476:
8474:
8471:
8469:
8466:
8464:
8461:
8459:
8456:
8454:
8451:
8449:
8446:
8444:
8441:
8439:
8436:
8434:
8431:
8429:
8426:
8424:
8423:Phencyclidine
8421:
8419:
8416:
8414:
8411:
8409:
8406:
8404:
8401:
8399:
8396:
8394:
8393:Nitrous oxide
8391:
8389:
8386:
8384:
8381:
8379:
8376:
8374:
8371:
8369:
8366:
8364:
8361:
8359:
8356:
8354:
8351:
8349:
8346:
8344:
8341:
8339:
8336:
8334:
8333:Levomethadone
8331:
8329:
8326:
8324:
8321:
8319:
8316:
8314:
8311:
8309:
8306:
8304:
8301:
8299:
8296:
8294:
8291:
8289:
8286:
8284:
8281:
8279:
8278:Hexafluronium
8276:
8274:
8271:
8269:
8266:
8264:
8261:
8259:
8256:
8254:
8251:
8249:
8246:
8244:
8241:
8239:
8236:
8234:
8231:
8229:
8226:
8224:
8221:
8219:
8216:
8214:
8211:
8209:
8206:
8204:
8201:
8199:
8196:
8194:
8191:
8189:
8186:
8184:
8181:
8179:
8176:
8174:
8171:
8169:
8168:Decamethonium
8166:
8164:
8161:
8159:
8156:
8154:
8151:
8149:
8146:
8144:
8141:
8139:
8138:Cisatracurium
8136:
8134:
8131:
8129:
8126:
8124:
8121:
8119:
8116:
8114:
8111:
8108:
8104:
8100:
8099:Bungarotoxins
8097:
8095:
8092:
8089:
8085:
8084:pentobarbital
8081:
8078:
8076:
8073:
8071:
8068:
8066:
8063:
8061:
8058:
8056:
8053:
8051:
8048:
8046:
8043:
8040:
8036:
8032:
8028:
8027:α-Neurotoxins
8025:
8023:
8020:
8018:
8015:
8014:
8012:
8006:
7999:
7995:
7989:
7986:
7984:
7981:
7979:
7976:
7974:
7971:
7969:
7966:
7964:
7961:
7959:
7956:
7954:
7951:
7949:
7946:
7944:
7941:
7939:
7936:
7934:
7931:
7929:
7926:
7924:
7921:
7919:
7916:
7914:
7911:
7909:
7906:
7904:
7901:
7899:
7896:
7894:
7891:
7889:
7886:
7884:
7881:
7879:
7876:
7874:
7871:
7869:
7866:
7864:
7861:
7859:
7856:
7854:
7851:
7849:
7846:
7844:
7841:
7839:
7836:
7834:
7831:
7828:
7824:
7821:
7819:
7816:
7814:
7811:
7809:
7806:
7804:
7801:
7799:
7796:
7794:
7791:
7789:
7786:
7784:
7781:
7779:
7776:
7774:
7771:
7769:
7766:
7764:
7761:
7759:
7756:
7754:
7751:
7749:
7746:
7744:
7741:
7739:
7736:
7734:
7731:
7729:
7728:Decamethonium
7726:
7724:
7721:
7719:
7716:
7714:
7711:
7709:
7706:
7704:
7701:
7699:
7696:
7694:
7691:
7689:
7686:
7684:
7681:
7679:
7676:
7674:
7671:
7669:
7666:
7664:
7663:Acetylcholine
7661:
7659:
7656:
7654:
7651:
7649:
7646:
7644:
7641:
7639:
7636:
7634:
7631:
7629:
7626:
7624:
7621:
7619:
7616:
7614:
7611:
7610:
7608:
7602:
7595:
7591:
7588:
7583:
7577:
7573:
7570:
7563:
7558:
7556:
7551:
7549:
7544:
7543:
7540:
7527:
7524:
7521:
7518:
7515:
7512:
7509:
7506:
7503:
7500:
7497:
7494:
7491:
7488:
7485:
7482:
7479:
7476:
7473:
7470:
7467:
7464:
7461:
7458:
7456:
7453:
7451:
7448:
7446:
7443:
7440:
7437:
7436:
7434:
7430:
7424:
7423:Carbamazepine
7421:
7419:
7416:
7415:
7413:
7409:
7403:
7400:
7398:
7395:
7393:
7392:Nortriptyline
7390:
7388:
7385:
7383:
7380:
7378:
7375:
7373:
7370:
7368:
7365:
7363:
7360:
7358:
7355:
7353:
7352:Amitriptyline
7350:
7349:
7347:
7345:
7341:
7335:
7332:
7330:
7327:
7326:
7324:
7322:
7318:
7317:-adrenoceptor
7310:
7304:
7301:
7299:
7296:
7294:
7291:
7289:
7286:
7285:
7283:
7281:
7274:Non-classical
7272:
7265:
7261:
7258:
7256:
7253:
7251:
7248:
7246:
7243:
7240:
7236:
7232:
7228:
7224:
7221:
7220:
7218:
7216:
7210:
7204:
7200:
7190:
7185:
7183:
7178:
7176:
7171:
7170:
7167:
7151:
7149:
7146:
7145:
7143:
7140:
7137:
7134:
7132:
7129:
7128:
7124:
7114:
7111:
7109:
7106:
7104:
7097:
7095:
7093:
7089:
7086:
7082:
7078:
7077:neurosteroids
7075:
7072:
7070:
7063:
7062:
7059:
7055:Miscellaneous
7052:
7048:
7033:
7032:levothyroxine
7025:
7021:
7018:
7015:
7011:
7007:
7004:
7002:
6999:
6996:
6992:
6988:
6984:
6980:
6979:brexpiprazole
6976:
6972:
6969:
6968:
6965:
6961:
6956:
6952:
6938:
6935:
6934:Irreversible:
6932:
6931:
6929:
6923:
6914:
6908:
6905:
6903:
6900:
6898:
6895:
6893:
6890:
6888:
6885:
6883:
6880:
6878:
6875:
6872:
6871:
6869:
6863:
6854:
6848:
6845:
6842:
6841:
6838:
6835:
6832:
6831:
6828:
6825:
6823:
6820:
6818:
6815:
6813:
6810:
6808:
6805:
6803:
6800:
6798:
6795:
6793:
6790:
6788:
6785:
6783:
6780:
6778:
6775:
6773:
6770:
6768:
6767:Isocarboxazid
6765:
6763:
6760:
6758:
6755:
6753:
6750:
6749:Irreversible:
6747:
6746:
6744:
6742:Non-selective
6740:
6736:
6732:
6727:
6723:
6709:
6706:
6705:
6703:
6699:
6693:
6690:
6688:
6685:
6683:
6680:
6678:
6675:
6674:
6672:
6667:
6661:
6655:
6652:
6650:
6647:
6645:
6642:
6640:
6639:Protriptyline
6637:
6635:
6632:
6630:
6627:
6625:
6622:
6620:
6617:
6615:
6614:Nortriptyline
6612:
6610:
6609:Nitroxazepine
6607:
6605:
6602:
6600:
6597:
6595:
6592:
6590:
6587:
6585:
6582:
6580:
6577:
6575:
6572:
6570:
6567:
6565:
6562:
6560:
6557:
6555:
6552:
6550:
6549:Demexiptiline
6547:
6545:
6542:
6540:
6537:
6535:
6532:
6530:
6527:
6525:
6524:Amitriptyline
6522:
6520:
6517:
6516:
6514:
6509:
6503:
6499:
6495:
6491:
6486:
6482:
6468:
6465:
6463:
6460:
6458:
6455:
6453:
6450:
6448:
6445:
6443:
6440:
6438:
6435:
6433:
6430:
6428:
6425:
6423:
6420:
6418:
6415:
6413:
6410:
6408:
6405:
6403:
6400:
6398:
6395:
6393:
6390:
6389:
6387:
6383:
6377:
6374:
6372:
6369:
6368:
6366:
6361:
6355:
6349:
6346:
6344:
6341:
6339:
6336:
6335:
6333:
6328:
6322:
6316:
6313:
6311:
6308:
6306:
6303:
6302:
6300:
6295:
6289:
6283:
6280:
6278:
6275:
6273:
6270:
6269:
6267:
6262:
6256:
6250:
6247:
6245:
6242:
6240:
6237:
6236:
6234:
6229:
6223:
6217:
6214:
6212:
6209:
6207:
6204:
6202:
6199:
6197:
6194:
6192:
6189:
6188:
6186:
6181:
6175:
6169:
6166:
6164:
6161:
6159:
6156:
6154:
6151:
6149:
6146:
6144:
6141:
6139:
6136:
6134:
6131:
6130:
6128:
6123:
6117:
6113:
6109:
6105:
6099:
6095:
6090:
6086:
6079:
6074:
6072:
6067:
6065:
6060:
6059:
6056:
6046:
6042:
6037:
6031:
6028:
6026:
6023:
6021:
6018:
6016:
6013:
6011:
6010:Thiopropamine
6008:
6006:
6003:
6001:
5998:
5996:
5993:
5991:
5988:
5986:
5983:
5981:
5978:
5976:
5973:
5971:
5968:
5966:
5963:
5961:
5958:
5956:
5953:
5951:
5948:
5946:
5943:
5941:
5938:
5936:
5933:
5931:
5928:
5926:
5923:
5921:
5918:
5916:
5913:
5911:
5910:Meclofenoxate
5908:
5906:
5903:
5901:
5898:
5896:
5893:
5891:
5888:
5886:
5883:
5881:
5878:
5876:
5873:
5871:
5868:
5866:
5863:
5861:
5860:Hexacyclonate
5858:
5856:
5853:
5851:
5848:
5846:
5843:
5841:
5838:
5836:
5833:
5831:
5828:
5826:
5823:
5821:
5818:
5816:
5813:
5811:
5808:
5806:
5803:
5801:
5798:
5796:
5793:
5791:
5788:
5786:
5783:
5781:
5778:
5776:
5775:Centanafadine
5773:
5771:
5768:
5766:
5763:
5761:
5758:
5756:
5753:
5751:
5748:
5746:
5743:
5741:
5738:
5736:
5733:
5731:
5728:
5726:
5723:
5721:
5718:
5717:
5715:
5711:
5705:
5702:
5700:
5697:
5695:
5692:
5690:
5687:
5685:
5682:
5680:
5677:
5675:
5672:
5670:
5667:
5665:
5662:
5660:
5657:
5655:
5652:
5650:
5647:
5646:
5644:
5642:
5638:
5632:
5629:
5627:
5624:
5622:
5619:
5617:
5614:
5612:
5609:
5607:
5604:
5602:
5599:
5597:
5594:
5592:
5589:
5587:
5584:
5582:
5579:
5577:
5574:
5572:
5569:
5567:
5564:
5562:
5559:
5557:
5554:
5552:
5549:
5547:
5544:
5542:
5539:
5537:
5534:
5532:
5529:
5527:
5524:
5522:
5519:
5517:
5514:
5512:
5511:Ioflupane (I)
5509:
5507:
5504:
5502:
5499:
5497:
5494:
5492:
5489:
5487:
5484:
5482:
5479:
5477:
5474:
5472:
5469:
5467:
5464:
5462:
5459:
5457:
5454:
5452:
5449:
5448:
5446:
5444:
5440:
5434:
5431:
5429:
5426:
5424:
5421:
5420:
5418:
5416:
5412:
5406:
5403:
5401:
5398:
5396:
5393:
5391:
5388:
5386:
5383:
5381:
5378:
5376:
5373:
5371:
5368:
5366:
5363:
5361:
5358:
5356:
5353:
5351:
5348:
5346:
5343:
5341:
5338:
5336:
5333:
5331:
5328:
5326:
5323:
5321:
5318:
5316:
5313:
5311:
5308:
5306:
5303:
5301:
5298:
5296:
5293:
5291:
5288:
5286:
5283:
5281:
5278:
5276:
5273:
5271:
5268:
5266:
5263:
5262:
5260:
5258:
5254:
5248:
5245:
5243:
5240:
5238:
5235:
5233:
5230:
5228:
5227:Phacetoperane
5225:
5223:
5220:
5217:
5213:
5210:
5208:
5205:
5203:
5200:
5198:
5195:
5193:
5190:
5188:
5185:
5183:
5180:
5178:
5175:
5173:
5170:
5168:
5165:
5163:
5160:
5158:
5155:
5153:
5150:
5148:
5145:
5143:
5140:
5138:
5135:
5134:
5132:
5130:
5126:
5120:
5117:
5115:
5112:
5110:
5107:
5105:
5102:
5100:
5097:
5095:
5092:
5090:
5087:
5085:
5082:
5080:
5077:
5075:
5072:
5070:
5067:
5065:
5062:
5060:
5057:
5055:
5052:
5050:
5047:
5046:
5044:
5042:
5038:
5032:
5029:
5027:
5024:
5022:
5019:
5017:
5016:Phenmetrazine
5014:
5012:
5009:
5007:
5004:
5002:
4999:
4997:
4994:
4992:
4989:
4987:
4984:
4982:
4979:
4977:
4974:
4972:
4969:
4967:
4964:
4963:
4961:
4959:
4955:
4949:
4946:
4944:
4943:Xylopropamine
4941:
4939:
4936:
4934:
4931:
4929:
4926:
4924:
4921:
4919:
4918:Theodrenaline
4916:
4914:
4911:
4909:
4906:
4904:
4901:
4898:
4894:
4891:
4889:
4886:
4884:
4881:
4879:
4876:
4874:
4871:
4869:
4866:
4864:
4861:
4859:
4856:
4854:
4851:
4849:
4846:
4844:
4841:
4839:
4836:
4834:
4833:Phenylephrine
4831:
4829:
4828:Phenylalanine
4826:
4824:
4821:
4819:
4816:
4814:
4811:
4809:
4806:
4804:
4801:
4799:
4796:
4794:
4791:
4789:
4786:
4784:
4781:
4779:
4776:
4774:
4771:
4769:
4768:Orciprenaline
4766:
4764:
4761:
4759:
4753:
4751:
4748:
4746:
4743:
4741:
4738:
4736:
4733:
4731:
4728:
4726:
4723:
4721:
4718:
4716:
4713:
4711:
4708:
4706:
4703:
4701:
4698:
4696:
4693:
4691:
4688:
4686:
4683:
4681:
4678:
4676:
4673:
4670:
4666:
4662:
4659:
4657:
4654:
4652:
4649:
4647:
4644:
4642:
4641:Mephentermine
4639:
4637:
4634:
4632:
4629:
4627:
4624:
4622:
4619:
4617:
4614:
4612:
4609:
4607:
4604:
4602:
4599:
4597:
4594:
4592:
4589:
4587:
4584:
4582:
4579:
4577:
4574:
4571:
4565:
4563:
4560:
4558:
4555:
4553:
4550:
4548:
4545:
4543:
4540:
4538:
4535:
4533:
4530:
4528:
4525:
4523:
4520:
4518:
4515:
4513:
4510:
4508:
4505:
4503:
4500:
4498:
4495:
4493:
4490:
4488:
4485:
4482:
4478:
4474:
4471:
4469:
4466:
4464:
4461:
4459:
4456:
4454:
4451:
4449:
4446:
4444:
4441:
4439:
4436:
4434:
4431:
4429:
4426:
4424:
4421:
4419:
4416:
4414:
4411:
4409:
4406:
4404:
4401:
4399:
4396:
4393:
4389:
4385:
4382:
4380:
4377:
4375:
4372:
4370:
4367:
4365:
4362:
4360:
4354:
4352:
4349:
4347:
4344:
4342:
4339:
4337:
4334:
4332:
4329:
4327:
4324:
4322:
4319:
4317:
4314:
4312:
4309:
4307:
4304:
4302:
4299:
4297:
4294:
4292:
4289:
4287:
4284:
4282:
4281:Benzphetamine
4279:
4277:
4274:
4272:
4269:
4267:
4264:
4262:
4259:
4257:
4254:
4251:
4247:
4243:
4240:
4238:
4235:
4233:
4230:
4228:
4225:
4223:
4222:2-Aminoindane
4220:
4218:
4215:
4213:
4210:
4208:
4205:
4203:
4200:
4198:
4195:
4193:
4190:
4188:
4185:
4183:
4180:
4178:
4175:
4173:
4170:
4168:
4165:
4163:
4160:
4158:
4155:
4153:
4150:
4148:
4145:
4143:
4140:
4138:
4135:
4133:
4130:
4128:
4125:
4123:
4120:
4118:
4115:
4113:
4110:
4108:
4105:
4103:
4100:
4099:
4097:
4095:
4091:
4085:
4082:
4080:
4077:
4075:
4072:
4070:
4067:
4065:
4062:
4060:
4057:
4055:
4052:
4050:
4047:
4046:
4044:
4042:
4038:
4032:
4029:
4027:
4024:
4022:
4019:
4017:
4014:
4012:
4009:
4007:
4004:
4003:
4001:
3999:
3995:
3989:
3986:
3984:
3981:
3979:
3976:
3974:
3971:
3969:
3966:
3964:
3961:
3959:
3956:
3954:
3951:
3949:
3946:
3945:
3943:
3941:
3937:
3931:
3928:
3926:
3923:
3921:
3918:
3916:
3913:
3911:
3908:
3906:
3903:
3901:
3898:
3896:
3893:
3891:
3888:
3886:
3883:
3881:
3878:
3876:
3873:
3871:
3868:
3866:
3863:
3861:
3858:
3856:
3853:
3851:
3848:
3846:
3843:
3841:
3838:
3836:
3833:
3831:
3828:
3826:
3823:
3821:
3818:
3816:
3813:
3811:
3808:
3806:
3803:
3801:
3798:
3796:
3793:
3791:
3788:
3786:
3783:
3781:
3778:
3776:
3773:
3772:
3770:
3768:
3764:
3758:
3755:
3753:
3750:
3748:
3745:
3743:
3740:
3738:
3735:
3733:
3730:
3728:
3725:
3723:
3720:
3718:
3715:
3713:
3712:Methcathinone
3710:
3708:
3705:
3703:
3700:
3698:
3695:
3693:
3690:
3688:
3685:
3683:
3680:
3678:
3675:
3673:
3670:
3668:
3665:
3663:
3660:
3658:
3655:
3653:
3650:
3648:
3645:
3643:
3640:
3638:
3635:
3633:
3630:
3628:
3625:
3623:
3620:
3618:
3615:
3613:
3610:
3608:
3605:
3604:
3602:
3600:
3596:
3590:
3587:
3585:
3582:
3580:
3577:
3575:
3572:
3571:
3569:
3567:
3563:
3557:
3554:
3552:
3551:Tenocyclidine
3549:
3547:
3546:Rolicyclidine
3544:
3542:
3541:Phencyclidine
3539:
3537:
3536:Phencyclamine
3534:
3532:
3529:
3527:
3524:
3522:
3519:
3517:
3514:
3512:
3509:
3507:
3506:Benocyclidine
3504:
3503:
3501:
3499:
3495:
3489:
3486:
3484:
3481:
3479:
3476:
3474:
3471:
3469:
3466:
3464:
3461:
3459:
3456:
3454:
3451:
3449:
3446:
3444:
3441:
3439:
3436:
3434:
3431:
3429:
3426:
3424:
3421:
3420:
3418:
3416:
3412:
3406:
3403:
3401:
3398:
3396:
3393:
3391:
3388:
3386:
3383:
3381:
3380:Isometheptene
3378:
3376:
3373:
3371:
3368:
3366:
3363:
3361:
3358:
3357:
3355:
3353:
3349:
3343:
3340:
3338:
3335:
3333:
3330:
3328:
3325:
3323:
3320:
3318:
3315:
3313:
3310:
3308:
3305:
3303:
3302:Aminophylline
3300:
3298:
3295:
3293:
3290:
3288:
3285:
3284:
3282:
3280:
3276:
3270:
3267:
3265:
3262:
3260:
3257:
3255:
3252:
3250:
3247:
3246:
3244:
3242:
3238:
3234:
3227:
3222:
3220:
3215:
3213:
3208:
3207:
3204:
3198:
3195:
3194:
3182:
3178:
3171:
3163:
3159:
3154:
3149:
3145:
3141:
3138:(4): 327–42.
3137:
3133:
3129:
3122:
3107:
3103:
3097:
3089:
3085:
3078:
3076:
3067:
3063:
3057:
3048:
3043:
3039:
3035:
3031:
3025:
3017:
3013:
3005:
2997:
2993:
2989:
2985:
2981:
2977:
2973:
2969:
2962:
2954:
2950:
2946:
2942:
2935:
2927:
2923:
2918:
2913:
2909:
2905:
2902:(7): 1560–9.
2901:
2897:
2893:
2886:
2878:
2872:
2868:
2861:
2853:
2847:
2843:
2836:
2834:
2819:on 2013-11-08
2818:
2814:
2810:
2803:, Driscol J.
2802:
2796:
2794:
2792:
2783:
2779:
2775:
2771:
2767:
2763:
2759:
2755:
2748:
2740:
2736:
2732:
2728:
2721:
2719:
2717:
2708:
2702:
2698:
2691:
2689:
2672:
2666:
2664:
2662:
2653:
2649:
2644:
2639:
2635:
2631:
2628:(4): 427–40.
2627:
2623:
2622:CNS Spectrums
2619:
2612:
2604:
2598:
2594:
2590:
2589:
2581:
2573:
2569:
2565:
2561:
2557:
2553:
2545:
2537:
2533:
2528:
2523:
2519:
2515:
2511:
2507:
2503:
2496:
2494:
2485:
2481:
2477:
2473:
2469:
2465:
2458:
2451:
2443:
2439:
2434:
2429:
2425:
2421:
2417:
2410:
2402:
2398:
2394:
2390:
2386:
2382:
2378:
2374:
2367:
2359:
2355:
2351:
2347:
2343:
2339:
2335:
2331:
2324:
2316:
2312:
2308:
2304:
2300:
2296:
2292:
2288:
2281:
2273:
2269:
2265:
2261:
2257:
2253:
2250:(3): 107–13.
2249:
2245:
2237:
2235:
2226:
2222:
2218:
2214:
2211:(6): 803–12.
2210:
2206:
2199:
2197:
2188:
2184:
2180:
2176:
2172:
2168:
2164:
2160:
2152:
2150:
2141:
2137:
2133:
2129:
2126:(5): 428–33.
2125:
2121:
2114:
2112:
2103:
2099:
2095:
2091:
2088:(2): 179–84.
2087:
2083:
2076:
2074:
2065:
2061:
2056:
2051:
2047:
2043:
2039:
2032:
2030:
2021:
2017:
2013:
2009:
2005:
2001:
1998:(7): 329–33.
1997:
1993:
1986:
1978:
1974:
1970:
1966:
1962:
1958:
1955:(5): 206–10.
1954:
1950:
1942:
1934:
1930:
1926:
1922:
1918:
1914:
1906:
1898:
1894:
1889:
1884:
1880:
1876:
1872:
1868:
1864:
1857:
1841:
1837:
1831:
1829:
1817:
1813:
1809:
1805:
1801:
1797:
1793:
1789:
1785:
1778:
1771:
1769:
1760:
1756:
1751:
1746:
1742:
1738:
1734:
1730:
1726:
1719:
1717:
1715:
1706:
1694:
1678:
1677:
1670:
1668:
1659:
1655:
1651:
1647:
1643:
1639:
1632:
1630:
1628:
1626:
1609:
1602:
1596:
1594:
1592:
1590:
1588:
1586:
1584:
1568:
1564:
1560:
1556:
1550:
1546:
1535:
1530:
1527:
1523:
1518:
1515:
1511:
1506:
1503:
1499:
1495:
1491:
1487:
1482:
1479:
1475:
1470:
1467:
1463:
1458:
1455:
1451:
1447:
1443:
1439:
1435:
1431:
1427:
1423:
1419:
1415:
1411:
1407:
1403:
1399:
1395:
1391:
1387:
1383:
1379:
1375:
1371:
1367:
1362:
1359:
1355:
1350:
1347:
1346:
1345:
1332:
1330:
1326:
1321:
1317:
1315:
1311:
1307:
1297:
1295:
1291:
1287:
1283:
1279:
1275:
1271:
1267:
1263:
1259:
1255:
1251:
1247:
1243:
1233:
1231:
1227:
1224:
1220:
1216:
1212:
1208:
1198:
1196:
1192:
1187:
1185:
1181:
1177:
1173:
1169:
1157:
1152:
1147:
1146:
1140:
1135:
1130:
1129:
1125:
1120:
1115:
1114:
1111:
1108:
1106:
1105:
1098:
1097:
1093:
1091:
1085:
1084:
1080:
1078:
1072:
1071:
1067:
1065:
1059:
1058:
1054:
1052:
1046:
1045:
1042:
1039:
1037:
1036:
1029:
1028:
1024:
1022:
1016:
1015:
1011:
1009:
1003:
1002:
998:
996:
990:
989:
985:
983:
977:
976:
972:
967:
962:
961:
958:
955:
953:
949:
943:
942:
939:
936:
934:
930:
924:
923:
915:
912:
911:
895:
893:
889:
885:
881:
877:
873:
869:
865:
861:
857:
853:
849:
845:
842:, reboxetine
841:
828:
825:
822:
821:
820:
818:
808:
805:
803:
799:
795:
794:accommodation
790:
782:
780:
775:
773:
769:
765:
761:
751:
749:
745:
741:
731:
722:
713:
709:
707:
702:
699:
694:
680:
674:
673:United States
670:
666:
662:
658:
654:
650:
646:
642:
638:
634:
624:
617:
611:
602:
597:
596:
593:
586:
577:
576:
573:
566:
563:
560:
558:
554:
547:
543:
542:
540:
537:
532:
525:
523:
519:
495:
493:
489:
484:
477:
473:
472:
470:
468:
464:
457:
453:
452:
450:
448:
444:
437:
432:
429:
425:
424:
422:
420:
416:
409:
405:
404:
402:
400:
396:
389:
385:
384:
382:
380:
376:
369:
365:
364:
362:
355:
351:
344:
339:
336:
332:
331:
329:
327:
323:
315:
311:
307:
306:
303:
296:
291:
287:
284:
282:
278:
275:12–12.5 hours
274:
272:
265:
261:
257:
254:
252:
248:
244:
242:
238:
234:
232:
228:
224:
220:
207:
204:
194:
191:
181:
178:
168:
167:
165:
163:
159:
154:
146:
141:
138:
137:
135:
133:
129:
125:
121:
118:
116:
110:
104:
95:
94:
92:
90:
84:
81:
77:
75:
71:
68:Clinical data
66:
61:
57:
51:
47:
41:
36:
19:
10979:
10978:
10963:
10951:
10948:
10938:
10848:Bietaserpine
10820:Amphetamines
10743:Mifepristone
10733:Medifoxamine
10615:
10558:Clomipramine
10553:Cianopramine
10544:
10397:Diclofensine
10367:Brasofensine
10343:
10267:
10255:Vortioxetine
10206:
10125:Escitalopram
10081:
10003:Indeloxazine
9995:
9932:
9915:Oxaprotiline
9896:
9884:Trimipramine
9839:Clomipramine
9834:Cianopramine
9829:Butriptyline
9820:
9673:Diclofensine
9643:Brasofensine
9619:
9543:
9531:Solriamfetol
9457:
9440:Teniloxazine
9419:
9400:Esreboxetine
9371:
9303:Solriamfetol
9223:Medifoxamine
9113:Dimethocaine
9103:Diclofensine
9075:
9027:
8915:Difluoropine
8910:Dichloropane
8895:Brasofensine
8881:
8869:Pyrovalerone
8845:
8770:Piperidines:
8769:
8719:Piperazines:
8718:
8508:Tubocurarine
8452:
8438:Promegestone
8433:Progesterone
8348:Mecamylamine
8158:Cyclopropane
8148:Coronaridine
8080:Barbiturates
8065:Anatruxonium
8035:α-cobratoxin
7878:Sazetidine A
7798:JNJ-39393406
7788:Ispronicline
7396:
7099:Oxitriptan (
7091:
6975:aripiprazole
6933:
6882:Metralindole
6873:
6843:
6833:
6812:Pivhydrazine
6802:Pheniprazine
6748:
6654:Trimipramine
6644:Quinupramine
6544:Clomipramine
6539:Butriptyline
6462:Teniloxazine
6457:Tandospirone
6442:Metryptamine
6437:Medifoxamine
6422:Indeloxazine
6376:Vortioxetine
6243:
6138:Escitalopram
5965:Oxaprotiline
5915:Medifoxamine
5835:Fenpentadiol
5815:Dimethocaine
5810:Diclofensine
5790:Cropropamide
5785:Clofenciclan
5740:Amiphenazole
5694:7-Methyl-αET
5689:6-Fluoro-αMT
5669:5-Fluoro-αMT
5664:5-Chloro-αMT
5659:4-Methyl-αMT
5654:4-Methyl-αET
5496:Difluoropine
5481:Cocaethylene
5466:Brasofensine
5405:Pyrovalerone
5257:Pyrrolidines
4976:Fenmetramide
4971:Fenbutrazate
4948:Zylofuramine
4908:Solriamfetol
4740:Norfenefrine
4646:Metanephrine
4572:(Selegiline)
4562:Isoprenaline
4492:Feprosidnine
4473:Fenfluramine
4468:Fenethylline
4453:Famprofazone
4326:Cinnamedrine
4256:Amphetaminil
4207:Amfepentorex
3885:Sazetidine A
3850:Ispronicline
3815:Bradanicline
3767:Cholinergics
3682:Ethcathinone
3566:Benzazepines
3521:Eticyclidine
3342:Theophylline
3327:Paraxanthine
3180:
3170:
3135:
3131:
3121:
3109:. Retrieved
3106:Adis Insight
3105:
3102:"Reboxetine"
3096:
3087:
3065:
3056:
3037:
3033:
3024:
3015:
3011:
3004:
2974:(3): 231–9.
2971:
2967:
2961:
2944:
2940:
2934:
2899:
2895:
2885:
2866:
2860:
2841:
2821:. Retrieved
2817:the original
2812:
2757:
2753:
2747:
2730:
2726:
2696:
2675:. Retrieved
2625:
2621:
2611:
2587:
2580:
2555:
2551:
2544:
2509:
2505:
2467:
2463:
2450:
2426:(3): 282–5.
2423:
2419:
2409:
2376:
2372:
2366:
2336:(3): 423–8.
2333:
2329:
2323:
2293:(6): 351–6.
2290:
2286:
2280:
2247:
2243:
2208:
2204:
2162:
2158:
2123:
2119:
2085:
2081:
2048:(3): 231–5.
2045:
2041:
1995:
1991:
1985:
1952:
1948:
1941:
1916:
1912:
1905:
1870:
1866:
1856:
1844:. Retrieved
1839:
1816:the original
1787:
1783:
1732:
1728:
1681:. Retrieved
1675:
1644:(1): 65–83.
1641:
1637:
1612:. Retrieved
1607:
1571:. Retrieved
1549:
1528:
1516:
1504:
1480:
1468:
1456:
1360:
1348:
1343:
1322:
1318:
1303:
1293:
1289:
1288:)-(–)- and (
1285:
1281:
1273:
1269:
1265:
1261:
1257:
1253:
1249:
1245:
1239:
1229:
1218:
1214:
1210:
1206:
1204:
1188:
1165:
1109:
1099:
1040:
1030:
956:
944:
937:
925:
898:Pharmacology
852:ketoconazole
843:
837:
834:Interactions
814:
806:
798:palpitations
791:
788:
776:
757:
737:
728:
719:
710:
703:
696:The British
695:
691:
683:Medical uses
636:
632:
631:
620:
614:
476:ChEMBL383921
313:
309:
268:Elimination
162:Legal status
156:Legal status
59:
55:
49:
45:
11043:Morpholines
10991:Adrenergics
10918:Valbenazine
10908:Rose bengal
10853:Deserpidine
10824:amphetamine
10774:levorphanol
10718:Dextrorphan
10671:ziprasidone
10653:pheniramine
10588:Lofepramine
10568:Desipramine
10517:Tesofensine
10507:Sibutramine
10482:Perafensine
10442:JNJ-7925476
10437:Indatraline
10382:Dasotraline
10352:Amifitadine
10331:Venlafaxine
10311:Milnacipran
10210:Etoperidone
10190:Seproxetine
10180:Pirandamine
10160:Omiloxetine
10140:Fluvoxamine
10100:Cericlamine
10090:Alaproclate
10037:levorphanol
9966:ziprasidone
9948:pheniramine
9920:Setiptiline
9905:Maprotiline
9864:Lofepramine
9844:Desipramine
9793:Tesofensine
9783:Sibutramine
9758:Perafensine
9718:JNJ-7925476
9713:Indatraline
9658:Dasotraline
9628:Amifitadine
9607:Venlafaxine
9582:Milnacipran
9511:Nomifensine
9476:Fencamfamin
9405:Lortalamine
9395:Edivoxetine
9385:Ciclazindol
9380:Alseroxylon
9328:Venlafaxine
9308:Tametraline
9298:Sibutramine
9273:Perafensine
9253:Nomifensine
9183:Indatraline
9158:Fencamfamin
9133:DOV-216,303
9128:DOV-102,677
9088:Dasotraline
9083:Ciclazindol
9041:Armodafinil
9036:Amifitadine
8985:Tesofensine
8793:Difemetorex
8613:Pirisudanol
8578:Cyprodenate
8558:Adafenoxate
8473:Surugatoxin
8463:Sevoflurane
8418:Pentolinium
8398:Norketamine
8318:Laudanosine
8248:Erythravine
8238:Encenicline
8223:Dipyrandium
8193:Dextrorphan
8039:α-conotoxin
7998:Antagonists
7983:WAY-317,538
7978:Varenicline
7968:Tropisetron
7958:Tebanicline
7903:SSR-180,711
7868:Rivanicline
7858:Pozanicline
7853:PNU-282,987
7848:PNU-120,596
7843:PHA-709,829
7838:PHA-543,613
7778:Galantamine
7753:Epiboxidine
7748:Epibatidine
7668:Altinicline
7402:Venlafaxine
7387:Moclobemide
7382:Milnacipran
7367:Desipramine
7293:Atomoxetine
7288:Armodafinil
7223:Amphetamine
7138:from market
7081:brexanolone
6995:risperidone
6892:Moclobemide
6874:Reversible:
6834:Reversible:
6757:Iproclozide
6692:Setiptiline
6687:Mirtazapine
6677:Maprotiline
6634:Propizepine
6619:Noxiptiline
6604:Metapramine
6594:Lofepramine
6564:Dimetacrine
6554:Desipramine
6427:Flupentixol
6412:Etryptamine
6397:Amisulpride
6392:Agomelatine
6338:Etoperidone
6315:Setiptiline
6310:Mirtazapine
6282:Nomifensine
6239:Atomoxetine
6216:Venlafaxine
6206:Milnacipran
6148:Fluvoxamine
6015:Thiothinone
6000:Tametraline
5985:Rauwolscine
5955:Nomifensine
5950:Nikethamide
5895:Lomevactone
5880:JNJ-7925476
5875:Indatraline
5850:GSK1360707F
5805:Desipramine
5795:Crotetamide
5780:Ciclazindol
5760:Benzydamine
5750:Atomoxetine
5745:Atipamezole
5641:Tryptamines
5611:Tesofensine
5177:Difemetorex
5129:Piperidines
5041:Piperazines
4903:Sibutramine
4873:Prenylamine
4823:Phentermine
4778:Oxifentorex
4675:Methoxamine
4651:Metaraminol
4487:Fenproporex
4458:Fencamfamin
4423:Epinephrine
4346:Clortermine
4336:Clobenzorex
4331:Clenbuterol
4306:Camfetamine
4242:Amphetamine
4212:Amidephrine
4084:Thozalinone
4064:Cyclazodone
4011:Armodafinil
3973:Pentetrazol
3953:Bicuculline
3940:Convulsants
3930:WAY-317,538
3925:Varenicline
3915:Tebanicline
3895:SSR-180,711
3880:Rivanicline
3875:Pozanicline
3870:PNU-282,987
3865:PNU-120,596
3860:PHA-543,613
3840:Epiboxidine
3835:Epibatidine
3800:Altinicline
3692:Flephedrone
3647:Amfepramone
3526:Gacyclidine
3370:Cyprodenate
3352:Alkylamines
3337:Theobromine
3269:Rimantadine
3241:Adamantanes
2941:Tetrahedron
2379:(1): 31–4.
1919:(1): 31–7.
1846:10 November
1701:|work=
1683:10 November
1614:10 November
1340:Brand names
1278:enantiomers
1213:)-(–) and (
1195:atomoxetine
1172:selectivity
1094:>10,000
1081:>10,000
1068:>10,000
1025:>10,000
1012:>10,000
999:>10,000
986:>10,000
973:>10,000
908:Reboxetine
892:fluvoxamine
868:ciclosporin
826:Tachycardia
529: g·mol
293:Identifiers
74:Trade names
11022:Categories
10967:SoRI-20041
10960:SoRI-20040
10888:Ketanserin
10815:Amiodarone
10778:tapentadol
10738:Mesembrine
10708:Delucemine
10685:esketamine
10598:Pipofezine
10583:Imipramine
10502:SEP-228432
10497:SEP-228431
10467:Nefazodone
10452:Liafensine
10422:Fezolamine
10412:DOV-216303
10407:DOV-102677
10362:Bicifadine
10357:Ansofaxine
10296:Eclanamine
10291:Duloxetine
10276:Bicifadine
10250:Vilazodone
10220:Lubazodone
10215:Litoxetine
10200:Zimelidine
10195:Sertraline
10170:Paroxetine
10165:Panuramine
10135:Fluoxetine
10130:Femoxetine
10110:Dapoxetine
10105:Citalopram
10029:tapentadol
10008:Nefazodone
9991:Ephenidine
9986:Dopexamine
9869:Melitracen
9859:Imipramine
9778:SEP-228432
9773:SEP-228431
9743:Nefazodone
9728:Liafensine
9698:Fezolamine
9688:DOV-216303
9683:DOV-102677
9638:Bicifadine
9633:Ansofaxine
9592:Nafenodone
9567:Eclanamine
9562:Duloxetine
9521:Radafaxine
9501:Manifaxine
9486:Lefetamine
9461:Amineptine
9445:Viloxazine
9420:Reboxetine
9415:Nisoxetine
9293:Sertraline
9283:Radafaxine
9268:Oroxylin A
9213:Manifaxine
9203:Liafensine
9193:Lefetamine
9173:GYKI-52895
9163:Fezolamine
9148:Esketamine
9143:Ephenidine
9066:BTS 74,398
9056:Ansofaxine
9051:Amineptine
8930:FP-β-CPPIT
8925:FE-β-CPPIT
8864:Prolintane
8757:Vanoxerine
8752:Nefazodone
8573:Citicoline
8553:Acetyl-coA
8537:Precursors
8513:Vanoxerine
8503:Tropeinium
8488:Toxiferine
8453:Reboxetine
8443:Radafaxine
8388:Neramexane
8378:Mivacurium
8373:Metocurine
8338:Malouetine
8303:Isoflurane
8258:Fazadinium
8253:Esketamine
8233:Doxacurium
8218:Dioscorine
8178:Desflurane
8143:Coclaurine
8075:Atracurium
8060:Amantadine
8050:Alcuronium
7803:Levamisole
7793:Ivermectin
7738:Dianicline
7698:Butinoline
7683:Anatoxin-a
7572:modulators
7418:Amantadine
7397:Reboxetine
7377:Imipramine
7372:Duloxetine
7334:Guanfacine
7303:Viloxazine
7280:stimulants
7215:stimulants
7113:Tryptophan
7085:zuranolone
6991:quetiapine
6987:olanzapine
6983:lurasidone
6937:Selegiline
6927:-selective
6907:Toloxatone
6902:Tetrindole
6897:Pirlindole
6877:Eprobemide
6867:-selective
6847:Bifemelane
6837:Caroxazone
6797:Phenelzine
6782:Mebanazine
6762:Iproniazid
6649:Tianeptine
6629:Pipofezine
6599:Melitracen
6579:Imipramine
6559:Dibenzepin
6519:Amineptine
6467:Tianeptine
6452:Pivagabine
6447:Oxaflozane
6407:Esketamine
6371:Vilazodone
6343:Nefazodone
6272:Amineptine
6249:Viloxazine
6244:Reboxetine
6196:Duloxetine
6168:Zimelidine
6163:Sertraline
6158:Paroxetine
6143:Fluoxetine
6133:Citalopram
5995:Setazindol
5980:Rasagiline
5970:PNU-99,194
5920:Mefexamide
5890:Leptacline
5885:Lazabemide
5855:GYKI-52895
5845:Gilutensin
5770:BTS 74,398
5735:Amineptine
5684:5-MeO-DIPT
5516:Norcocaine
5506:FP-β-CPPIT
5501:FE-β-CPPIT
5423:Oxiracetam
5400:Prolintane
5119:Vanoxerine
5031:Radafaxine
5006:PD-128,907
5001:Oxaflozane
4986:Manifaxine
4913:Synephrine
4893:Salbutamol
4888:Ropinirole
4843:Pholedrine
4783:Oxilofrine
4773:Ortetamine
4763:Octopamine
4730:Nisoxetine
4586:Lophophine
4576:Lefetamine
4557:Isoetarine
4552:Iofetamine
4517:Hexapradol
4507:Furfenorex
4502:Formetorex
4448:Etilefrine
4433:Etafedrine
4403:Dopexamine
4388:Dextrodopa
4379:Dobutamine
4364:Denopamine
4351:Cypenamine
4321:Cilobamine
4276:Benfluorex
4261:Arbutamine
4202:Amfecloral
4192:Alfetamine
4074:Fluminorex
4069:Fenozolone
4059:Clominorex
4041:Oxazolines
4021:CRL-40,941
4016:CRL-40,940
3983:Strychnine
3978:Picrotoxin
3948:Anatoxin-a
3830:Dianicline
3747:Pentedrone
3717:Methedrone
3707:Mephedrone
3657:Buphedrone
3652:Benzedrone
3599:Cathinones
3556:Tiletamine
3516:Esketamine
3458:LY-503,430
3453:LY-404,187
3375:Heptaminol
3365:Cypenamine
3317:Dimethazan
3259:Bromantane
3254:Amantadine
3249:Adapromine
3233:Stimulants
3018:: 235–242.
2823:2014-03-31
2643:2292/61637
1573:2023-08-16
1542:References
1329:fluoxetine
1205:Both the (
888:fluoxetine
880:sertraline
876:paroxetine
872:tacrolimus
848:papaverine
748:narcolepsy
734:Other uses
633:Reboxetine
534:3D model (
522:Molar mass
436:L94J81YNNY
428:947S0YZ36I
399:ChemSpider
343:98769-84-7
335:71620-89-8
326:CAS Number
302:IUPAC name
262:-mediated)
251:Metabolism
32:Reboxetine
10980:See also:
10955:SoRI-9804
10903:Reserpine
10873:GBR-12935
10868:Efavirenz
10788:Roxindole
10766:methadone
10753:N-Me-5-HT
10723:Efavirenz
10681:3-MeO-PCP
10624:Amoxapine
10492:Pridefine
10462:Naphyrone
10326:Tofenacin
10245:Trazodone
10235:SB-649915
10230:Quipazine
10225:LY-393558
10150:Ifoxetine
10145:Indalpine
10021:methadone
9910:Mianserin
9900:Amoxapine
9768:Pridefine
9738:Naphyrone
9602:Tofenacin
9552:CP-39,332
9471:Fencamine
9466:Bupropion
9435:Tandamine
9430:Talsupram
9390:Daledalin
9288:Rimcazole
9278:Pridefine
9243:Modafinil
9168:Fluorenol
9138:Efavirenz
9071:Bupropion
9031:Adrafinil
8995:Tropoxane
8885:Altropane
8882:Tropanes:
8859:Naphyrone
8823:Pipradrol
8742:GBR-13098
8737:GBR-13069
8732:GBR-12935
8727:GBR-12783
8413:Pentamine
8408:Pempidine
8358:Methadone
8353:Memantine
8273:Halothane
8263:Gallamine
8243:Enflurane
8198:Diadonium
8113:Bupropion
7898:SIB-1553A
7893:SIB-1508Y
7883:SB-206553
7708:Carbachol
7688:AR-R17779
7678:Anatabine
7673:Anabasine
7638:A-867,744
7633:A-582,941
7628:A-366,833
7496:Serotonin
7362:Buspirone
7357:Bupropion
7329:Clonidine
7298:Modafinil
7148:Phase III
7136:Withdrawn
7001:Buspirone
6887:Minaprine
6822:Tedizolid
6817:Safrazine
6792:Octamoxin
6787:Nialamide
6777:Linezolid
6772:Isoniazid
6682:Mianserin
6624:Opipramol
6589:Iprindole
6569:Dosulepin
6534:Amoxapine
6490:Tricyclic
6348:Trazodone
6305:Mianserin
6277:Bupropion
6211:Tofenacin
6153:Indalpine
6102:Specific
6030:Yohimbine
6005:Tandamine
5975:PRC200-SS
5870:Indanorex
5840:Gamfexine
5830:Fenisorex
5755:Bemegride
5679:5-MeO-αMT
5674:5-MeO-αET
5621:Tropoxane
5395:Picilorex
5385:Naphyrone
5232:Pipradrol
5094:GBR-13119
5089:GBR-13098
5084:GBR-13069
5079:GBR-12935
5074:GBR-12783
4813:Phenatine
4636:Mefenorex
4570:-Deprenyl
4542:Ibopamine
4527:Hordenine
4512:Gepefrine
4463:Fencamine
4418:Ephedrine
4408:Droxidopa
4359:-Deprenyl
4237:Acridorex
4031:Modafinil
4026:Fluorenol
4006:Adrafinil
3998:Eugeroics
3963:Flurothyl
3890:SIB-1553A
3810:Arecoline
3805:Anabasine
3795:AR-R17779
3780:A-366,833
3752:Pentylone
3732:Mexedrone
3727:Methylone
3697:Hexedrone
3672:Cathinone
3662:Bupropion
3589:SKF-82958
3584:SKF-81297
3579:SKF-77434
3483:Sunifiram
3468:Org 26576
3463:Nooglutyl
3415:Ampakines
3395:Octodrine
3332:SCH-58261
3312:CGS-15943
3264:Memantine
3066:CNN/Money
2809:Database"
2677:20 August
1735:: c4737.
1703:ignored (
1693:cite book
1638:CNS Drugs
1316:in 2003.
1310:Pharmacia
1268:)-, and (
1236:Chemistry
1226:isoenzyme
884:quinidine
661:off-label
557:Chirality
281:Excretion
270:half-life
113:Routes of
87:Pregnancy
78:Edronax,
10942:Luteolin
10893:Lobeline
10883:Ibogaine
10782:tramadol
10728:Hypidone
10689:ketamine
10667:loxapine
10527:Tropanes
10457:Mazindol
10447:JZ-IV-10
10281:CP-39332
10240:TGBA01AD
10033:tramadol
9976:ketamine
9962:loxapine
9803:Tropanes
9733:Mazindol
9723:JZ-IV-10
9425:Talopram
9410:Mazindol
9375:Amedalin
9233:Metaphit
9228:Mesocarb
9218:Mazindol
9188:Ketamine
8990:Troparil
8747:JJC8-088
8625:See also
8567:lecithin
8543:prodrugs
8493:Tramadol
8343:ME-18-MC
8308:Ketamine
8298:Ibogaine
8118:BW284C51
7873:RJR-2429
7863:Pyrantel
7823:Nicotine
7818:Morantel
7808:Lobeline
7773:EVP-6124
7768:EVP-4473
7723:Cytisine
7718:Cotinine
7623:A-84,543
7594:Agonists
7460:Dopamine
7321:agonists
7074:GABAkine
6752:Benmoxin
6708:Tiazesim
6432:Ketamine
6417:Gepirone
6041:ATC code
5905:Mazindol
5865:Idazoxan
5825:Etamivan
5820:Efaroxan
5649:4-HO-αMT
5443:Tropanes
5415:Racetams
5270:4-Cl-PVP
5247:SCH-5472
5207:JZ-IV-10
5099:JJC8-088
5049:2C-B-BZP
4996:Morforex
4991:Morazone
4938:Tyrosine
4933:Tyramine
4923:Tiflorex
4808:Pentorex
4710:Morforex
4656:Mesocarb
4497:Fludorex
4398:Dopamine
4392:Levodopa
4341:Cloforex
4122:2-OH-PEA
4079:Pemoline
4054:Aminorex
3968:Gabazine
3855:Nicotine
3825:Cytisine
3820:Cotinine
3775:A-84,543
3687:Ethylone
3667:Butylone
3612:3,4-DMMC
3574:6-Br-APB
3531:Ketamine
3488:Unifiram
3307:Caffeine
3162:14647527
3111:17 April
2926:20393461
2774:12649369
2739:10534319
2652:35837681
2572:23899496
2536:29368813
2484:12562576
2442:11322710
2401:41990481
2393:16452053
2358:24287884
2350:15358988
2315:21260625
2307:11110011
2272:41617072
2264:21432596
2225:18315452
2179:21312292
2140:15843764
2102:18439114
2064:22615662
2020:19996027
2012:12415550
1977:12495057
1969:15359375
1933:11838623
1897:29477251
1812:35858125
1804:19185342
1759:20940209
1658:72813017
1567:Archived
1529:Zuolexin
1517:Yeluoshu
1174:for the
823:Sweating
817:overdose
811:Overdose
764:epilepsy
760:glaucoma
623:(verify)
562:Racemate
379:DrugBank
190:Class C1
132:ATC code
120:By mouth
102: B1
89:category
10878:GZ-793A
10822:(e.g.,
10760:(e.g.,
10758:Opioids
10679:(e.g.,
10665:(e.g.,
10631:(e.g.,
10619:A-80426
10616:Others:
10578:Doxepin
10531:cocaine
10529:(e.g.,
10477:NS-2359
10472:Nefopam
10427:HDMP-28
10417:EXP-561
10377:Cocaine
10306:McN5652
10185:RTI-353
10015:(e.g.,
10013:Opioids
9974:(e.g.,
9960:(e.g.,
9938:(e.g.,
9933:Others:
9854:Doxepin
9807:cocaine
9805:(e.g.,
9753:NS-2359
9748:Nefopam
9703:HDMP-28
9693:EXP-561
9653:Cocaine
9577:McN5652
9496:LR-5182
9258:NS-2359
9248:Nefopam
9208:LR-5182
9153:EXP-561
9028:Others:
8980:RTI-336
8975:RTI-229
8970:RTI-177
8965:RTI-150
8960:RTI-126
8955:RTI-121
8950:RTI-113
8945:RTI-112
8905:Cocaine
8803:HDMP-28
8722:DBL-583
8563:Choline
8123:BW-A444
8101:(e.g.,
8094:BNC-210
8082:(e.g.,
8045:ABT-126
8029:(e.g.,
7988:XY-4083
7953:TC-6683
7948:TC-5619
7943:TC-5214
7938:TC-2216
7933:TC-1827
7928:TC-1734
7923:TC-1698
7833:NS-1738
7827:tobacco
7713:Choline
7658:ABT-894
7653:ABT-560
7648:ABT-418
7643:ABT-202
7528:(SNDRI)
7006:Lithium
6574:Doxepin
6106:and/or
6020:Trazium
5945:Nefopam
5900:LR-5182
5601:RTI-386
5596:RTI-371
5591:RTI-354
5586:RTI-336
5581:RTI-229
5576:RTI-177
5571:RTI-150
5566:RTI-126
5556:RTI-120
5551:RTI-113
5546:RTI-112
5486:Cocaine
5275:5-DBFPV
5222:Nocaine
5069:DBL-583
4428:Epinine
4311:Cathine
4187:AL-1095
4132:2,3-MDA
3988:Thujone
3910:TC-2216
3905:TC-1827
3900:TC-1698
3790:ABT-418
3785:ABT-202
3478:S-18986
3448:IDRA-21
3153:6741698
2988:1814741
2917:3055469
2805:"PDSD K
2801:Roth BL
2782:5897406
2593:254–255
2527:6491172
2187:8634761
2055:3232108
1888:5889788
1750:2954275
1481:Prolift
1469:Norebox
1361:Edronax
1349:Davedax
1300:History
1280:, the (
1186:(DAT).
1055:11,900
637:Edronax
527:313.397
492:Formula
388:DB00234
354:PubChem
148:)
142: (
140:N06AX18
124:tablets
18:Edronax
10932:Others
10487:PRC200
10432:HP-505
10175:PIM-35
9763:PRC200
9708:HP-505
9516:O-2172
9263:O-2172
8940:RTI-55
8153:Curare
8070:AQW051
8017:18-MAC
7973:UB-165
7783:GTS-21
7613:5-HIAA
7581:nAChRs
7522:(NDRI)
7516:(SNRI)
7510:(SSRI)
7504:(SERT)
7498:(5-HT)
7441:(ADHD)
7131:WHO-EM
6844:Mixed:
6701:Others
6385:Others
6293:NaSSAs
6025:UH-232
5960:O-2172
5713:Others
5541:RTI-51
5536:RTI-32
5531:RTI-31
5305:α-PHPP
5295:α-PHiP
5290:α-PCYP
5054:3C-PEP
4616:MDMPEA
3920:UB-165
3845:GTS-21
3637:4-MEAP
3443:CX-717
3438:CX-691
3433:CX-614
3428:CX-546
3423:CX-516
3160:
3150:
2996:874781
2994:
2986:
2924:
2914:
2873:
2848:
2780:
2772:
2737:
2703:
2650:
2599:
2570:
2534:
2524:
2482:
2440:
2399:
2391:
2356:
2348:
2313:
2305:
2270:
2262:
2223:
2185:
2177:
2138:
2100:
2062:
2052:
2018:
2010:
1975:
1967:
1931:
1895:
1885:
1867:Lancet
1810:
1802:
1784:Lancet
1757:
1747:
1656:
1555:Anvisa
1505:Solvex
1457:Irenor
1314:Pfizer
1223:CYP3A4
1126:6,700
860:CYP3A4
856:CYP2D6
840:CYP3A4
653:Pfizer
641:others
639:among
572:SMILES
467:ChEMBL
456:D08472
408:112870
368:127151
260:CYP3A4
245:97–98%
201:
188:
175:
80:others
10803:VMATs
9015:WF-33
9010:WF-31
9005:WF-23
9000:WF-11
8541:(and
8523:Xenon
8022:18-MC
8001:(and
7597:(and
7492:(NRI)
7486:(NET)
7474:(DRI)
7468:(DAT)
7101:5-HTP
6665:TeCAs
6326:SARIs
6260:NDRIs
6179:SNRIs
6121:SSRIs
5800:D-161
5720:2-MDP
5631:WF-33
5626:WF-23
5370:MOPPP
5365:MOPVP
5345:MDPBP
5340:MDPPP
5325:DMPVP
5315:α-PVT
5310:α-PVP
5300:α-PHP
5285:α-PBP
5280:α-PPP
5104:MeOPP
5064:CM156
4981:G-130
4700:MMDMA
4631:MDPEA
4182:6-FNE
4177:4-MTA
4172:4-MMA
3622:4-CMC
3617:4-BMC
2992:S2CID
2778:S2CID
2460:(PDF)
2420:Sleep
2397:S2CID
2354:S2CID
2311:S2CID
2268:S2CID
2183:S2CID
2016:S2CID
1973:S2CID
1819:(PDF)
1808:S2CID
1780:(PDF)
1654:S2CID
1604:(PDF)
1260:)-, (
1252:)-, (
1191:GIRKs
938:273.5
920:(nM)
779:MAOIs
706:IQWiG
592:InChI
536:JSmol
286:Urine
256:Liver
10843:AZIK
10832:MDMA
10321:PPPA
10064:SRIs
10053:SERT
9597:PPPA
9354:NRIs
8854:MDPV
8701:DRIs
8203:DHβE
8004:NAMs
7600:PAMs
7480:(NE)
7462:(DA)
7197:ADHD
7067:SAMe
6507:TCAs
6492:and
6227:NRIs
6089:N06A
6045:N06B
5380:MDPV
5360:MPPP
5355:MPHP
5350:MPBP
5335:FPVP
5330:FPOP
5114:oMPP
5109:MBZP
4868:PPAP
4863:PMMA
4858:PMEA
4798:PCMA
4705:MMMA
4695:MMDA
4626:MDPR
4621:MDOH
4606:MDEA
4601:MDBU
4591:MBDB
4522:HMMA
4413:EBDB
4384:DOPA
4301:BPAP
4167:4-MA
3958:DMCM
3473:PEPA
3158:PMID
3113:2016
2984:PMID
2922:PMID
2871:ISBN
2846:ISBN
2770:PMID
2735:PMID
2701:ISBN
2679:2017
2648:PMID
2597:ISBN
2568:PMID
2532:PMID
2480:PMID
2438:PMID
2389:PMID
2346:PMID
2303:PMID
2260:PMID
2221:PMID
2175:PMID
2136:PMID
2098:PMID
2060:PMID
2042:Daru
2008:PMID
1965:PMID
1929:PMID
1893:PMID
1848:2013
1800:PMID
1755:PMID
1705:help
1685:2013
1616:2013
1150:GIRK
1133:nACh
1118:mACh
1032:5-HT
1018:5-HT
1005:5-HT
992:5-HT
979:5-HT
957:13.4
928:SERT
913:Site
858:and
850:and
698:MHRA
667:and
663:for
447:KEGG
419:UNII
235:≥94%
225:data
10838:APP
9343:NET
9061:BTQ
8900:CFT
8690:DAT
7277:CNS
7208:CNS
7030:),
6918:MAO
6858:MAO
6359:SMS
5765:BTQ
5704:αMT
5699:αET
5526:PTT
5521:PIT
5390:PEP
5059:BZP
4853:PMA
4848:PIA
4803:PHA
4793:PCA
4788:PBA
4685:MMA
4291:BOH
4286:BDB
3148:PMC
3140:doi
3042:doi
2976:doi
2949:doi
2912:PMC
2904:doi
2762:doi
2758:305
2638:hdl
2630:doi
2560:doi
2522:PMC
2514:doi
2472:doi
2468:160
2428:doi
2381:doi
2338:doi
2295:doi
2252:doi
2213:doi
2167:doi
2128:doi
2090:doi
2050:PMC
2000:doi
1957:doi
1921:doi
1883:PMC
1875:doi
1871:391
1792:doi
1788:373
1745:PMC
1737:doi
1733:341
1729:BMJ
1646:doi
1110:312
1041:457
965:DAT
947:NET
651:by
358:CID
312:-(2
310:rel
203:POM
145:WHO
11024::
11005:•
11001:•
10997:•
10993:•
10989:•
10985:•
10962:;
10830:,
10826:,
10780:,
10776:,
10772:,
10768:,
10764:,
10695:,
10691:,
10687:,
10683:,
10669:,
10655:,
10651:,
10647:,
10643:,
10639:,
10635:,
10035:,
10031:,
10027:,
10023:,
10019:,
9978:,
9964:,
9950:,
9946:,
9942:,
8105:,
8086:,
8037:,
8033:,
7237:,
7233:,
7229:,
7144::
7083:,
7038:))
7034:(T
7026:(T
7012:,
6993:,
6989:,
6985:,
6981:,
6977:,
6043::
4667:,
4479:,
4390:,
4248:,
3179:.
3156:.
3146:.
3134:.
3130:.
3104:.
3086:.
3074:^
3064:.
3036:.
3032:.
3014:.
2990:.
2982:.
2972:16
2970:.
2945:41
2943:.
2920:.
2910:.
2900:35
2898:.
2894:.
2832:^
2811:.
2790:^
2776:.
2768:.
2756:.
2731:27
2729:.
2715:^
2687:^
2660:^
2646:.
2636:.
2626:28
2624:.
2620:.
2595:.
2566:.
2556:47
2554:.
2530:.
2520:.
2508:.
2504:.
2492:^
2478:.
2466:.
2462:.
2436:.
2424:24
2422:.
2418:.
2395:.
2387:.
2377:40
2375:.
2352:.
2344:.
2334:18
2332:.
2309:.
2301:.
2291:15
2289:.
2266:.
2258:.
2246:.
2233:^
2219:.
2209:17
2207:.
2195:^
2181:.
2173:.
2163:25
2161:.
2148:^
2134:.
2124:44
2122:.
2110:^
2096:.
2086:18
2084:.
2072:^
2058:.
2046:19
2044:.
2040:.
2028:^
2014:.
2006:.
1996:17
1994:.
1971:.
1963:.
1953:37
1951:.
1927:.
1917:63
1915:.
1891:.
1881:.
1869:.
1865:.
1838:.
1827:^
1806:.
1798:.
1786:.
1782:.
1767:^
1753:.
1743:.
1731:.
1727:.
1713:^
1697::
1695:}}
1691:{{
1666:^
1652:.
1642:12
1640:.
1624:^
1606:.
1582:^
1534:CN
1522:CN
1510:DE
1498:VE
1496:,
1494:CL
1492:,
1490:BR
1488:,
1486:AR
1474:ES
1462:ES
1450:UK
1448:,
1446:TR
1444:,
1442:TH
1440:,
1438:CH
1436:,
1434:SE
1432:,
1430:ZA
1428:,
1426:PT
1424:,
1422:PL
1420:,
1418:PH
1416:,
1414:NO
1412:,
1410:NZ
1408:,
1406:MX
1404:,
1402:IT
1400:,
1398:IL
1396:,
1394:IE
1392:,
1390:DE
1388:,
1386:FI
1384:,
1382:DK
1380:,
1378:CZ
1376:,
1374:BE
1372:,
1370:AT
1368:,
1366:AU
1354:IT
1197:.
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