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routes. Enteral administration involves the esophagus, stomach, and small and large intestines (i.e., the gastrointestinal tract). Methods of administration include oral, sublingual (dissolving the drug under the tongue), and rectal. Parenteral administration is via a peripheral or central vein. In
368:, and therefore, the amount of drug entering the systemic circulation following administration may vary significantly for different individuals and drugs. Rectal administration is not subject to extensive first pass metabolism.
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542:
456:
107:
Enteral administration may be divided into three different categories, depending on the entrance point into the GI tract: oral (by
827:
124:
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436:
103:
A man with a nasogastric tube allowing food and medicine to be delivered through the nose and straight to the stomach
295:
The mechanism for drug absorption from the intestine is for most drugs passive transfer, a few exceptions include
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1005:
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lining the inside of the intestines. The rate at which this happens is largely determined by two factors:
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24:
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119:). (Gastric introduction involves the use of a tube through the nasal passage (
85:
32:
16:
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312:
20:
A medical professional demonstrates how to offer oral medication to a dummy.
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Drugs given by enteral administration may be subjected to significant
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72:, the route of drug administration is important because it affects
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28:
A medical professional injects medication into a gastric tube.
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123:) or a tube in the belly leading directly to the stomach (
63:), which occurs from routes outside the GI tract, such as
913:
858:
290:
311:
to occur, the drug has to diffuse through the lipid
330:Factors influencing gastrointestinal absorption:
127:). Rectal administration usually involves rectal
1402:
464:
471:
457:
359:
98:
55:nutrition or drug administration (Greek
31:
23:
15:
403:"Enteral administration - pharmacology"
1403:
452:
426:
828:Heated humidified high-flow therapy
13:
1092:
1030:
923:
303:, which are both absorbed through
291:Drug absorption from the intestine
226:Osmotic controlled release capsule
14:
1422:
36:Administering medication rectally
1270:
796:
557:
551:
420:
395:
1:
596:Effervescent powder or tablet
388:
1380:Patient-controlled analgesia
685:Orally disintegrating tablet
429:Rang and Dale's Pharmacology
49:human gastrointestinal tract
7:
371:
10:
1427:
891:Relative analgesia machine
305:carrier-mediated transport
43:administration is food or
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1307:
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1080:
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431:. Elsevier. p. 104.
335:Gastrointestinal motility
136:
1411:Routes of administration
480:Routes of administration
378:Enteric (disambiguation)
115:), and rectal (from the
111:), gastric (through the
94:
1006:Extra-amniotic infusion
611:Molecular encapsulation
543:Osmotic delivery system
538:Time release technology
209:Time release technology
1309:Central nervous system
1097:
1035:
963:Mucoadhesive microdisc
928:
104:
51:. This contrasts with
37:
29:
21:
1152:Transfersome vesicles
1096:
1034:
1011:Intravesical infusion
927:
366:first pass metabolism
360:First pass metabolism
349:size and formulation.
145:Rectal administration
102:
35:
27:
19:
838:Metered-dose inhaler
823:Anesthetic vaporizer
427:Rang, H. P. (2007).
1263:Transdermal implant
1223:(into tissue/blood)
1000:Intrauterine device
881:Anaesthetic machine
876:Oxygen concentrator
139:Oral administration
84:. The term is from
45:drug administration
1375:Nanocell injection
1098:
1036:
929:
783:Dry-powder inhaler
105:
38:
30:
22:
1398:
1397:
1394:
1393:
1225:
1187:Transdermal spray
1182:Transdermal patch
1172:Medicated shampoo
903:
902:
899:
898:
886:Medical inhalants
833:Medical inhalants
761:Respiratory tract
755:
754:
649:
648:
288:
287:
1418:
1274:
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1229:
1221:
808:
804:
800:
771:
770:
700:Sublingual drops
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325:lipid solubility
317:epithelial cells
309:passive transfer
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1370:Intraperitoneal
1342:musculoskeletal
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1299:Intra-articular
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501:Digestive tract
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353:Physicochemical
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74:drug metabolism
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1072:Nutrient enema
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78:drug clearance
59:, "besides" +
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1360:Intramuscular
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1317:Intracerebral
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1137:Iontophoresis
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871:Nasal cannula
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313:cell membrane
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129:suppositories
126:
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92:
91:'intestine'.
90:
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83:
79:
75:
71:
66:
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58:
54:
50:
46:
42:
34:
26:
18:
1365:Intraosseous
1355:Intracardiac
1294:Intravitreal
1256:Injector pen
1251:Subcutaneous
1222:
1192:Jet injector
1177:Dermal patch
1023:
990:Vaginal ring
958:Insufflation
710:Effervescent
504:
484:dosage forms
428:
422:
410:. Retrieved
406:
397:
383:Feeding tube
363:
329:
301:fluorouracil
294:
161:
160:
152:
151:
144:
137:
106:
88:
70:pharmacology
60:
56:
40:
39:
1350:Intravenous
1337:Circulatory
1322:Intrathecal
1246:Intradermal
1238:transdermal
1205:Parenterals
1111:Topical gel
1067:Murphy drip
1045:Suppository
933:Nasal spray
867:Oxygen mask
716:Chewing gum
655:Oral mucosa
343:blood flow.
236:Murphy drip
202:Suppository
80:, and thus
65:intravenous
1210:Injections
973:Urogenital
909:Ophthalmic
765:inhalation
739:Toothpaste
667:sublingual
631:Suspension
601:Herbal tea
389:References
341:Splanchnic
321:Ionization
214:Suspension
53:parenteral
1215:infusions
1147:Liposomes
943:Eye drops
938:Ear drops
849:Vaporizer
844:Nebulizer
734:Mouthwash
663:sublabial
586:Electuary
576:Decoction
1405:Category
1386:PIC line
1327:Epidural
1167:Lip balm
1142:Hydrogel
1133:solution
1116:Liniment
1101:Ointment
1060:Hydrogel
1055:Solution
1040:Ointment
980:Ointment
953:Hydrogel
948:Ointment
744:Ointment
705:Lozenges
695:Lollipop
641:Tincture
626:Solution
606:Hydrogel
591:Emulsion
533:Pastille
412:19 April
372:See also
355:factors.
347:Particle
297:levodopa
281:hydrogel
270:Tincture
231:Emulsion
185:Ointment
180:Solution
125:PEG tube
47:via the
1086:topical
1024:enteral
985:Pessary
815:Liquids
788:Smoking
726:Liquids
621:Softgel
568:Liquids
528:Capsule
505:enteral
315:of the
197:Softgel
163:Liquids
121:NG tube
113:stomach
89:enteros
61:enteros
41:Enteral
1281:Organs
1162:Lotion
1082:Dermal
1020:Rectal
995:Douche
775:Solids
712:tablet
677:Solids
659:buccal
616:Powder
581:Elixir
523:Tablet
515:Solids
435:
307:. For
259:Elixir
192:Tablet
154:Solids
117:rectum
82:dosage
1157:Cream
1121:Paste
1050:Enema
1002:(IUD)
918:nasal
840:(MDI)
748:Spray
636:Syrup
245:Syrup
219:Enema
109:mouth
95:Forms
86:Greek
1382:pump
1234:Skin
1131:DMSO
1126:Film
914:otic
869:and
690:Film
492:Oral
433:ISBN
414:2018
323:and
299:and
175:Pill
57:para
859:Gas
131:.)
1407::
916:,
665:,
661:,
482:,
405:.
327:.
169:-
76:,
1339:,
1240:)
1236:(
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1084:(
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1022:(
911:,
807:0
803:0
767:)
763:(
669:)
657:(
507:)
503:(
472:e
465:t
458:v
441:.
416:.
337:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.