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Sackmann dedicated a lifetime of research towards probing the living cell with tools of physics, long before biophysics was the mode of the day. Considered as a father of biophysics in Europe, he pioneered, along with others, the idea of a "bottom up" approach towards understanding the cell –
565:
Wiegand, G.; Neumaier, K. R.; Sackmann, E. (1998). "Microinterferometry: Three-Dimensional
Reconstruction of Surface Microtopography for Thin-Film and Wetting Studies by Reflection Interference Contrast Microscopy (RICM)".
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starting from relatively simple systems like lipid bilayers, giant vesicles and actin in solution and going towards more and more complex systems to reach eventually an understanding at the level of the entire cell.
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198:. Later, along with his students he laid the foundations of our current understanding of membrane adhesion. Over the years, his team developed and improved the technique of
732:"Microrheometry of semiflexible actin networks through enforced single-filament reptation: Frictional coupling and heterogeneities in entangled networks"
789:
847:
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Uhde, J; Feneberg, W; Ter-Oganessian, N; Sackmann, E; Boulbitch, A (2005). "Osmotic force-controlled microrheometry of entangled actin networks".
206:– IRM) – a powerful tool to probe adhesion of membranes and thin films. Collaborations with theoreticians like Reinhard Lipowsky, Udo Seifert and
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in Göttingen, Germany. Between 1974 and 1980 he was professor of physics and head of the biophysics department at
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capable of exerting very small pulling forces. He contributed to our understanding of the dynamics of single
123:(26 November 1934 – 29 May 2024) was a German experimental physicist and a pioneer of biophysics in Europe.
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of macromolecular networks, applications of solid-supported lipid-protein membranes, ultrathin hydrated
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Limozin, L.; Roth, A.; Sackmann, E. (2005). "Microviscoelastic Moduli of
Biomimetic Cell Envelopes".
159:, and from 1980 until retirement in 2003 he held the same positions at the Physics Department of the
20:
528:"Imaging optical thicknesses and separation distances of phospholipid vesicles at solid surfaces"
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have led to seminal works on adhesion of cell mimetic giant vesicles (also called
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Untersuchung der indirekten
Kernspinkopplung zwischen Protonen und Kohlenstoff-13
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Untersuchung der indirekten
Kernspinkopplung zwischen Protonen und Kohlenstoff-13
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Sackmann, E.; Bruinsma, R. F. (2002). "Cell
Adhesion as Wetting Transition?".
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in 2002. In recognition of his research work, in 2006, he was awarded the
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473:(1 February 2011). "Theodor Förster: a giant of modern photochemistry".
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10.1002/1439-7641(20020315)3:3<262::AID-CPHC262>3.0.CO;2-U
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and its dynamics. To study cytoskeletal dynamics, his team developed
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Following the awarding of his PhD, Sackmann then spent two years at
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375:"Physics of cell adhesion: Some lessons from cell-mimetic systems"
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Sackmann obtained his MSc (1961) and PhD (1964) degrees from the
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Traueranzeige in der SĂĽddeutschen
Zeitung 7 June 2024
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Academic staff of the
Technical University of Munich
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19:"Sackmann" redirects here. For other meanings, see
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270:layers and polymer/membrane composite films and
736:Proceedings of the National Academy of Sciences
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153:Max Planck Institute for Biophysical Chemistry
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175:More than 200 publications and several books
151:in Murray Hill, New Jersey, and six years at
239:His research interests included: physics of
200:reflection interference contrast microscopy
286:Along with Reinhard Lipowsky, he authored
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848:Fellows of the American Physical Society
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843:Academic staff of the University of Ulm
304:fellow of the American Physical Society
288:The Structure and Dynamics of Membranes
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373:Sackmann, E.; Smith, A. S. A. (2014).
177:Literatur von und ĂĽber Erich Sackmann
730:Dichtl, M. A.; Sackmann, E. (2002).
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290:. With Rudolf Merkel, he published
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329:Interference reflection microscopy
204:interference reflection microscopy
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526:Rädler, J.; Sackmann, E. (1993).
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278:of membrane associated proteins.
217:Another of his interests was the
236:as well as intact living cells.
179:testify to his contributions to
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243:and function of artificial and
187:. His early work was mainly on
16:German biophysicist (1934–2024)
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202:– RICM (which is quantitative
161:Technical University of Munich
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709:10.1103/PhysRevLett.94.198102
666:10.1103/PhysRevLett.95.178101
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312:DPG, German Physical Society
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274:as a new tool to study the
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149:Bell Telephone Laboratories
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254:of cells, physics of the
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360:, retrieved 7 June 2024.
21:Sackman (disambiguation)
833:Scientists at Bell Labs
689:Physical Review Letters
646:Physical Review Letters
133:University of Stuttgart
74:University of Stuttgart
757:10.1073/pnas.052432499
532:Journal de Physique II
489:10.1002/CPHC.201100041
292:Lehrbuch der Biophysik
282:Selected bibliography
823:German biophysicists
790:"APS Fellow Archive"
588:10.1364/AO.37.006892
465:Clemens F Kaminski;
272:neutron reflectivity
245:biological membranes
748:2002PNAS...99.6533D
701:2005PhRvL..94s8102U
658:2005PhRvL..95q8101L
580:1998ApOpt..37.6892W
552:10.1051/jp2:1993163
544:1993JPhy2...3..727R
391:2014SMat...10.1644S
308:Stern-Gerlach-Medal
399:10.1039/C3SM51910D
742:(10): 6533–6538.
302:He was elected a
298:Awards and honors
223:magnetic tweezers
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81:Scientific career
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208:Robijn Bruinsma
192:liquid crystals
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568:Applied Optics
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538:(5): 727–748.
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483:(3): 423–424.
471:Klaus Schulten
467:Erich Sackmann
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796:17 September
794:. Retrieved
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828:2024 deaths
818:1934 births
379:Soft Matter
339:J. S. Ploem
229:filaments,
181:soft matter
62:Baiersbronn
812:Categories
453:Q126172843
345:References
324:Lipid raft
252:microscopy
194:and lipid
185:biophysics
91:Biophysics
54:1934-11-26
513:Q48447464
497:1439-4235
212:liposomes
196:membranes
189:lyotropic
127:Education
64:, Germany
776:11997438
717:16090216
674:16383873
631:12503172
596:18301506
509:Wikidata
505:21344585
449:Wikidata
445:53303559
433:(1964),
417:24651316
318:See also
310:by the
264:rheology
262:: micro-
234:networks
167:Research
744:Bibcode
697:Bibcode
654:Bibcode
576:Bibcode
540:Bibcode
408:4028615
387:Bibcode
268:polymer
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258:based
143:Career
109:(1964)
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98:Thesis
87:Fields
792:. APS
256:actin
231:actin
227:actin
798:2020
772:PMID
713:PMID
670:PMID
627:PMID
592:PMID
501:PMID
493:ISSN
441:OCLC
413:PMID
183:and
47:Born
762:PMC
752:doi
705:doi
662:doi
619:doi
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485:doi
403:PMC
395:doi
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