110:
197:, under clothing straps, or in children's hair, ear, or neck. Most people who get infected do not remember seeing a tick or the bite. The EM rash appears typically one or two weeks (range 3–32 days) after the bite. The most distinctive features of the EM rash are the speed and extent to which it expands, respectively 2–3 cm per day and up to a diameter of 5–70 cm (50% attain more than 16 cm). The rash is usually circular or oval, red or bluish, and may have an elevated or darker center. In about 79% of cases in Europe but only 19% of cases in endemic areas of the U.S., the rash gradually clears from the center toward the edges, possibly forming a "bull's eye" pattern. The rash may feel warm but usually is not itchy, is rarely tender or painful, and takes up to four weeks to resolve if untreated.
153:
165:
94:
139:(bull's-eye lesion) are talking about erythema migrans. However, the appearance of erythema migrans can vary considerably: while some look like a bull's eye, in the U.S. most are evenly red or bluish, without a central or ring-like clearing. A minority of patients never have any rash. Because Lyme disease can within a few weeks cause long-term neurologic complications, persons with a rash and recent history of outdoor activities where Lyme is common should seek a doctor for diagnosis.
201:
222:
208:
The EM rash is often accompanied by symptoms of a viral-like illness, including fatigue, headache, body aches, fever, and chills, but usually not nausea or upper-respiratory problems. These symptoms may also appear without a rash, or linger after the rash disappears. Lyme can progress to later stages
109:
212:
A person with an asymptomatic EM rash can easily miss its significance. However, if the initial EM rash is not treated, the infection can disseminate through the lymphatic system or blood. Within days or weeks, additional EM rashes, usually smaller, can appear at other sites, or the infection can
93:
779:
Smith RP, Schoen RT, Rahn DW, Sikand VK, Nowakowski J, Parenti DL, Holman MS, Persing DH, Steere AC (2002). "Clinical characteristics and treatment outcome of early Lyme disease in patients with microbiologically confirmed erythema migrans".
135:"Erythema migrans is the only manifestation of Lyme disease in the United States that is sufficiently distinctive to allow clinical diagnosis in the absence of laboratory confirmation." Often, but not always, mentions of a
280:
In the 1920s, French physicians Garin and
Bujadoux described a patient with meningoencephalitis, painful sensory radiculitis, and erythema migrans following a tick bite, and they postulated the symptoms were due to a
1022:
1002:
1103:
600:"The clinical assessment, treatment, and prevention of Lyme disease, Human Granulocytic Anaplasmosis, and Babesiosis: Clinical Practice Guidelines by the Infectious Diseases Society of America"
2184:
687:
1096:
277:
symptoms and signs in a number of cases and that both sexes were affected. This rash was known as erythema chronicum migrans, the skin rash found in early-stage Lyme disease.
264:
first presented research about an expanding, ring-like lesion he had observed. Afzelius published his work 12 years later and speculated the rash came from the bite of an
1089:
2177:
236:
is also sometimes called erythema migrans or EM. The associated infectious agent has not been determined. Antibiotic treatment resolves the illness quickly.
2170:
2621:
3019:
2205:
1596:
2912:
728:
323:
17:
2786:
929:
Blanton L, Keith B, Brzezinski W (June 2008). "Southern Tick-Associated Rash
Illness: Erythema Migrans Is Not Always Lyme Disease".
1903:
872:
229:
73:
does not represent an allergic reaction to the bite, but rather an actual skin infection of one of the Lyme bacteria species
62:
2614:
431:
2816:
122:) and may have no definite pattern, as in this Lyme rash on a woman's neck. Rashes from non-Lyme causes may look similar.
1685:
1586:
2723:
2700:
2162:
1695:
2607:
2695:
1654:
1280:
152:
2969:
2930:
2821:
2337:
1847:
1538:
1375:
2361:
2890:
2661:
2578:
2253:
2014:
1769:
1460:
1390:
643:
164:
2974:
2950:
1764:
1295:
1250:
170:
After 8 weeks, the rash cleared from the center toward the edges and looked a bit more like a bull's eye.
2895:
2756:
2117:
1837:
518:
Boyce, RM; Pretsch, P; Tyrlik, K; Schulz, A; Giandomenico, DA; Barbarin, AM; Williams, C (March 2024).
2994:
2885:
2880:
2569:
2550:
2516:
2039:
74:
1081:
2741:
2523:
2472:
1882:
1528:
1465:
1360:
1041:
2945:
2688:
2562:
2147:
1842:
1561:
1533:
1163:
2555:
2396:
2197:
2122:
2034:
1350:
232:(STARI) produces a similar rash pattern although it develops more quickly and is smaller. This
1075:
3029:
3024:
2844:
2761:
2705:
2530:
2461:
2024:
1951:
1639:
1173:
1153:
793:
103:
but in only 20% of cases in the United States. (20 percent of Lyme infections show no rash.)
2989:
2839:
2796:
2791:
2746:
2509:
2502:
2452:
2332:
2300:
1370:
1168:
1143:
568:
204:
Visible part of the Lyme disease rash showing its characteristic asymmetrical cross-section
8:
2935:
2867:
2811:
2766:
2278:
2193:
2092:
2029:
2004:
1978:
1832:
1810:
1405:
1365:
1285:
1275:
1026:
38:
750:"In reply: Comment on 'Identifying erythema migrans rash in patients with Lyme disease'"
544:
519:
2806:
2801:
2751:
2671:
2440:
2266:
2243:
1941:
1805:
1690:
1649:
1523:
1518:
1513:
1340:
1031:
715:
1035:
828:
492:
2922:
2645:
2430:
1999:
1705:
1581:
1576:
1455:
1429:
1355:
1345:
1183:
1158:
1052:
946:
911:
868:
832:
797:
761:
720:
655:
621:
580:
549:
467:
423:
381:
373:
31:
2192:
888:
James AM, Liveris D, Wormser GP, Schwartz I, Montecalvo MA, Johnson BJ (June 2001).
862:
2906:
2356:
2350:
2344:
2322:
2306:
2097:
1946:
1852:
1800:
1670:
1445:
1380:
938:
901:
824:
789:
710:
702:
611:
539:
531:
459:
363:
286:
2984:
2728:
2641:
2587:
2271:
2223:
2082:
2009:
1680:
1395:
1240:
1178:
1046:
942:
520:"Delayed Diagnosis of Locally Acquired Lyme Disease, Central North Carolina, USA"
450:
Tibbles CD, Edlow JA (20 June 2007). "Does This
Patient Have Erythema Migrans?".
190:
2718:
2683:
2583:
2541:
2376:
2201:
2142:
2132:
2049:
1591:
1419:
411:
261:
1057:
1011:
749:
3013:
2872:
2401:
2214:
2127:
2102:
2057:
2019:
1887:
1754:
1614:
1566:
1498:
1470:
463:
377:
177:
The initial sign of about 80% of Lyme infections is an erythema migrans (EM)
136:
41:, despite that both often involve target lesions (but from different causes).
2979:
2901:
2493:
2312:
2072:
1644:
1624:
1439:
1434:
1424:
1265:
950:
915:
890:"Borrelia lonestari infection after a bite by an Amblyomma americanum tick"
836:
801:
765:
724:
659:
625:
584:
553:
535:
471:
427:
385:
294:
290:
58:
706:
213:
cause more serious complications in the nervous system, heart, or joints.
2599:
2445:
2420:
2107:
1932:
1634:
1300:
368:
351:
249:
245:
994:
2831:
2386:
2067:
1908:
1785:
1503:
1475:
1245:
964:
LipschĂĽtz, B. (1931). "Zur
Kenntnis der "Erythema chronicum migrans"".
282:
274:
30:
For the tongue condition also sometimes called "erythema migrans", see
642:
Ogden NH, Lindsay LR, Morshed M, Sockett PN, Artsob H (January 2008).
2636:
2467:
2233:
2112:
2062:
1826:
1413:
1385:
1290:
1125:
1111:
1071:
317:
81:
66:
200:
2961:
2858:
2477:
2290:
2249:
2137:
1759:
1739:
1675:
1629:
1571:
1508:
1450:
1270:
1219:
1148:
906:
889:
616:
599:
598:
Wormser GP, Dattwyler RJ, Shapiro ED, et al. (November 2006).
233:
65:(STARI). It can appear anywhere from one day to one month after a
1936:
1790:
1700:
1619:
1606:
1556:
1485:
1209:
1204:
1199:
863:
Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007).
1548:
1493:
1260:
1255:
1229:
1138:
1006:
266:
182:
181:
at the site of a tick bite, often near skin folds, such as the
499:. Centers for Disease Control and Prevention. 21 December 2018
289:
described several cases of chronic lymphocytic meningitis and
1214:
221:
194:
186:
2258:
1795:
1314:
1133:
1015:
887:
270:
178:
70:
54:
641:
567:
Trayes, KP; Savage, K; Studdiford, JS (1 September 2018).
409:
410:
Wright WF, Riedel DJ, Talwani R, Gilliam BL (June 2012).
260:
In a 1909 meeting of the
Swedish Society of Dermatology,
158:
This rash did not at first look at all like a bull's eye.
630:"pp. 1101–2 Background and Diagnosis of Erythema Migrans
517:
216:
597:
928:
566:
778:
984:
853:. The American journal of medicine, 130(2), 231-233.
644:"The rising challenge of Lyme borreliosis in Canada"
318:"Lone star tick a concern, but not for Lyme disease"
252:. Amoxicillin in children less than 8 years of age.
1112:Diseases of the skin and appendages by morphology
851:Not all erythema migrans lesions are Lyme disease
487:
485:
483:
481:
3011:
743:
741:
244:Both Lyme disease and STARI can be treated with
61:, and can also (but less commonly) be caused by
478:
445:
443:
441:
2615:
2178:
1597:Pityriasis lichenoides et varioliformis acuta
1097:
963:
738:
405:
403:
401:
399:
397:
395:
1251:Dermatofibroma (benign fibrous histiocytoma)
808:
449:
345:
343:
285:infection. In the 1940s, German neurologist
681:
679:
677:
675:
673:
671:
669:
438:
2913:Acute generalized exanthematous pustulosis
2629:
2622:
2608:
2185:
2171:
1104:
1090:
569:"Annular Lesions: Diagnosis and Treatment"
412:"Diagnosis and management of Lyme disease"
392:
324:Centers for Disease Control and Prevention
99:In Europe, 80% of Lyme rashes look like a
2787:Acquired C1 esterase inhibitor deficiency
2384:
905:
714:
615:
543:
367:
340:
312:
310:
2428:
814:
666:
352:"Diagnostic Utility of Erythema Migrans"
220:
199:
922:
794:10.7326/0003-4819-136-6-200203190-00005
747:
685:
434:from the original on 27 September 2013.
27:A rash in several vector-borne diseases
14:
3020:Bacterium-related cutaneous conditions
3012:
1904:Disseminated intravascular coagulation
560:
349:
307:
2840:Episodic angioedema with eosinophilia
2603:
2166:
1085:
881:
815:Edlow JA (2002). "Erythema migrans".
493:"Lyme disease rashes and look-alikes"
230:Southern tick-associated rash illness
217:Southern tick-associated rash illness
63:southern tick-associated rash illness
511:
337:Page last reviewed: October 22, 2015
293:, some of which were accompanied by
2817:Urticaria-like follicular mucinosis
695:The New England Journal of Medicine
24:
1729:
1686:Postinflammatory hyperpigmentation
209:without these symptoms or a rash.
25:
3041:
1587:Transient acantholytic dermatosis
980:
688:"Clinical practice. Lyme disease"
57:often seen in the early stage of
2724:Localized heat contact urticaria
2701:Secondary cold contact urticaria
1696:Idiopathic guttate hypomelanosis
163:
151:
108:
92:
1706:Hypopigmented mycosis fungoides
957:
856:
843:
772:
142:
130:
2696:Primary cold contact urticaria
1947:Lichen sclerosis et atrophicus
1655:Subcorneal pustular dermatosis
1281:Infantile digital fibromatosis
635:
591:
13:
1:
2970:Necrolytic migratory erythema
2931:Erythema annulare centrifugum
2822:Chronic spontaneous urticaria
1539:Epidermolysis bullosa simplex
1376:Langerhans cell histiocytosis
829:10.1016/S0025-7125(03)00085-3
300:
80:. The rash's name comes from
2662:Urticarial allergic eruption
2579:Streptobacillus moniliformis
2015:Systemic lupus erythematosus
1770:Systemic lupus erythematosus
1461:Systemic lupus erythematosus
943:10.1097/SMJ.0b013e31817a8b3f
524:Emerging Infectious Diseases
356:Clinical Infectious Diseases
239:
7:
2951:Annular erythema of infancy
2338:Louse borne relapsing fever
1296:Lymphangioma circumscriptum
350:Naktin, Jaan Peter (2017).
10:
3046:
2896:Toxic epidermal necrolysis
2757:Delayed pressure urticaria
2362:Tick borne relapsing fever
2118:Mucous membrane pemphigoid
966:Acta Dermato-Venereologica
255:
225:Erythema migrans by STARI.
51:erythema chronicum migrans
36:
29:
18:Erythema chronicum migrans
2995:Necrolytic acral erythema
2959:
2921:
2886:Erythema multiforme major
2881:Erythema multiforme minor
2866:
2857:
2830:
2779:
2737:
2714:
2679:
2670:
2654:
2635:
2570:Fusobacterium polymorphum
2551:Fusobacterium necrophorum
2540:
2517:Capnocytophaga canimorsus
2492:
2419:
2375:
2288:
2231:
2222:
2213:
2081:
2048:
1992:
1977:
1968:
1925:
1896:
1875:
1866:
1819:
1778:
1747:
1736:
1718:
1663:
1605:
1547:
1484:
1404:
1333:
1322:
1313:
1228:
1192:
1124:
1117:
988:
573:American Family Physician
84:for "migrating redness."
2891:Stevens–Johnson syndrome
2742:Dermatographic urticaria
2524:Porphyromonas gingivalis
2473:Lymphogranuloma venereum
1883:Thrombocytopenic purpura
1529:Dermatitis herpetiformis
1514:Acute contact dermatitis
1466:Pityriasis rubra pilaris
1391:Wiskott–Aldrich syndrome
1361:Lichen simplex chronicus
1241:Epidermal inclusion cyst
464:10.1001/jama.297.23.2617
37:Not to be confused with
2946:Erythema gyratum repens
2563:Fusobacterium nucleatum
2148:Squamous-cell carcinoma
2143:Systemic histoplasmosis
1534:Porphyria cutanea tarda
1164:Squamous-cell carcinoma
686:Shapiro ED (May 2014).
2630:Urticaria and erythema
2397:Leptospira interrogans
2123:Cicatricial pemphigoid
2040:Acne keloidalis nuchae
2035:Folliculitis decalvans
536:10.3201/eid3003.231302
226:
205:
2845:Hereditary angioedema
2762:Cholinergic urticaria
2706:Reflex cold urticaria
2531:Prevotella intermedia
2462:Chlamydia trachomatis
2025:Loose anagen syndrome
1952:Necrobiosis lipoidica
1888:Actinic/solar purpura
1562:Insect bite reactions
1351:Seborrheic dermatitis
1174:Merkel-cell carcinoma
1154:Molluscum contagiosum
707:10.1056/NEJMcp1314325
648:Can. Commun. Dis. Rep
224:
203:
2990:Generalized erythema
2797:Autoimmune urticaria
2792:Adrenergic urticaria
2747:Vibratory angioedema
2510:Tannerella forsythia
2503:Bacteroides fragilis
2453:Chlamydia pneumoniae
2333:Borrelia recurrentis
2301:Borrelia burgdorferi
1848:Annulare centrifugum
1371:Glucagonoma syndrome
1169:Basal-cell carcinoma
1144:Seborrheic keratosis
867:. St. Louis: Mosby.
291:polyradiculoneuritis
2936:Erythema marginatum
2868:Erythema multiforme
2812:Schnitzler syndrome
2767:Aquagenic urticaria
2556:Lemierre's syndrome
2279:Treponema denticola
2093:Aphthous stomatitis
2030:Lichen planopilaris
2005:Androgenic alopecia
1811:Fixed drug eruption
1386:Pemphigus foliaceus
1286:Granular cell tumor
972:. Stockholm: 100–2.
748:Juckett, G (2014),
734:on 19 October 2016.
120:"migrating redness"
39:erythema multiforme
2807:Galvanic urticaria
2802:Exercise urticaria
2752:Pressure urticaria
2672:Physical urticaria
2655:Allergic urticaria
2441:Chlamydia psittaci
2267:Treponema carateum
2244:Treponema pallidum
2194:Bacterial diseases
2113:Pemphigus vulgaris
1942:Granuloma annulare
1806:Carcinoid syndrome
1691:Tuberous sclerosis
1650:Coccidioidomycosis
1524:Bullous pemphigoid
1519:Pemphigus vulgaris
1451:Secondary syphilis
1341:Contact dermatitis
369:10.1093/cid/cix544
227:
206:
3007:
3006:
3003:
3002:
2923:Figurate erythema
2853:
2852:
2775:
2774:
2597:
2596:
2488:
2487:
2415:
2414:
2411:
2410:
2371:
2370:
2160:
2159:
2156:
2155:
2000:Telogen effluvium
1964:
1963:
1960:
1959:
1921:
1920:
1917:
1916:
1862:
1861:
1714:
1713:
1582:Lichen spinulosus
1577:Keratosis pilaris
1456:Mycosis fungoides
1356:Stasis dermatitis
1346:Atopic dermatitis
1309:
1308:
1184:Trichoepithelioma
1159:Actinic keratosis
1067:
1066:
874:978-1-4160-2999-1
849:Goddard J (2017)
817:Med Clin North Am
701:(18): 1724–1731.
604:Clin. Infect. Dis
362:(12): 2156–2157.
32:Geographic tongue
16:(Redirected from
3037:
2975:Erythema toxicum
2941:Erythema migrans
2907:Erythema nodosum
2864:
2863:
2677:
2676:
2652:
2651:
2624:
2617:
2610:
2601:
2600:
2426:
2425:
2382:
2381:
2357:Borrelia parkeri
2351:Borrelia duttoni
2345:Borrelia hermsii
2323:Neuroborreliosis
2318:Erythema migrans
2307:Borrelia afzelii
2229:
2228:
2220:
2219:
2187:
2180:
2173:
2164:
2163:
2098:Oral candidiasis
1975:
1974:
1873:
1872:
1801:Erythema nodosum
1745:
1744:
1734:
1733:
1727:
1726:
1671:Tinea versicolor
1509:Bullous impetigo
1446:Pityriasis rosea
1381:Lichen sclerosus
1366:Darier's disease
1331:
1330:
1320:
1319:
1276:Kaposi's sarcoma
1122:
1121:
1106:
1099:
1092:
1083:
1082:
986:
985:
974:
973:
961:
955:
954:
926:
920:
919:
909:
885:
879:
878:
860:
854:
847:
841:
840:
812:
806:
805:
776:
770:
769:
754:Am Fam Physician
745:
736:
735:
733:
727:. Archived from
718:
692:
683:
664:
663:
639:
633:
632:
619:
595:
589:
588:
564:
558:
557:
547:
515:
509:
508:
506:
504:
489:
476:
475:
447:
436:
435:
416:Am Fam Physician
407:
390:
389:
371:
347:
338:
336:
334:
332:
314:
287:Alfred Bannwarth
167:
155:
116:Erythema migrans
112:
96:
53:is an expanding
47:Erythema migrans
21:
3045:
3044:
3040:
3039:
3038:
3036:
3035:
3034:
3010:
3009:
3008:
2999:
2985:Palmar erythema
2955:
2917:
2871:
2849:
2826:
2780:Other urticaria
2771:
2733:
2729:Solar urticaria
2710:
2666:
2639:
2631:
2628:
2598:
2593:
2588:Haverhill fever
2536:
2484:
2407:
2367:
2284:
2224:Spirochaetaceae
2209:
2191:
2161:
2152:
2084:
2077:
2044:
2010:Alopecia areata
1988:
1970:
1956:
1913:
1892:
1868:
1858:
1815:
1774:
1760:Viral exanthems
1738:
1722:
1720:
1710:
1681:Pityriasis alba
1659:
1601:
1543:
1480:
1400:
1396:Zinc deficiency
1326:
1324:
1305:
1233:
1224:
1188:
1179:Nevus sebaceous
1113:
1110:
1068:
1063:
1062:
997:
983:
978:
977:
962:
958:
927:
923:
886:
882:
875:
861:
857:
848:
844:
813:
809:
777:
773:
746:
739:
731:
690:
684:
667:
640:
636:
610:(9): 1089–134.
596:
592:
565:
561:
516:
512:
502:
500:
491:
490:
479:
458:(23): 2617–27.
448:
439:
422:(11): 1086–93.
408:
393:
348:
341:
330:
328:
316:
315:
308:
303:
258:
248:, particularly
242:
219:
175:
174:
173:
172:
171:
168:
160:
159:
156:
145:
133:
128:
127:
126:
123:
113:
104:
97:
75:from the genus
42:
35:
28:
23:
22:
15:
12:
11:
5:
3043:
3033:
3032:
3027:
3022:
3005:
3004:
3001:
3000:
2998:
2997:
2992:
2987:
2982:
2977:
2972:
2966:
2964:
2957:
2956:
2954:
2953:
2948:
2943:
2938:
2933:
2927:
2925:
2919:
2918:
2916:
2915:
2910:
2898:
2893:
2888:
2883:
2877:
2875:
2861:
2855:
2854:
2851:
2850:
2848:
2847:
2842:
2836:
2834:
2828:
2827:
2825:
2824:
2819:
2814:
2809:
2804:
2799:
2794:
2789:
2783:
2781:
2777:
2776:
2773:
2772:
2770:
2769:
2764:
2759:
2754:
2749:
2744:
2738:
2735:
2734:
2732:
2731:
2726:
2721:
2719:Heat urticaria
2715:
2712:
2711:
2709:
2708:
2703:
2698:
2693:
2692:
2691:
2684:Cold urticaria
2680:
2674:
2668:
2667:
2665:
2664:
2658:
2656:
2649:
2633:
2632:
2627:
2626:
2619:
2612:
2604:
2595:
2594:
2592:
2591:
2584:Rat-bite fever
2574:
2573:
2566:
2559:
2546:
2544:
2542:Fusobacteriota
2538:
2537:
2535:
2534:
2527:
2520:
2513:
2506:
2498:
2496:
2490:
2489:
2486:
2485:
2483:
2482:
2481:
2480:
2475:
2470:
2457:
2456:
2449:
2436:
2434:
2423:
2417:
2416:
2413:
2412:
2409:
2408:
2406:
2405:
2392:
2390:
2379:
2377:Leptospiraceae
2373:
2372:
2369:
2368:
2366:
2365:
2341:
2328:
2327:
2326:
2325:
2320:
2315:
2296:
2294:
2286:
2285:
2283:
2282:
2275:
2263:
2262:
2261:
2256:
2239:
2237:
2226:
2217:
2211:
2210:
2202:proteobacteria
2190:
2189:
2182:
2175:
2167:
2158:
2157:
2154:
2153:
2151:
2150:
2145:
2140:
2135:
2133:Coxsackievirus
2130:
2125:
2120:
2115:
2110:
2105:
2100:
2095:
2089:
2087:
2079:
2078:
2076:
2075:
2070:
2065:
2060:
2054:
2052:
2046:
2045:
2043:
2042:
2037:
2032:
2027:
2022:
2017:
2012:
2007:
2002:
1996:
1994:
1990:
1989:
1987:
1986:
1983:
1981:
1972:
1966:
1965:
1962:
1961:
1958:
1957:
1955:
1954:
1949:
1944:
1939:
1929:
1927:
1923:
1922:
1919:
1918:
1915:
1914:
1912:
1911:
1906:
1900:
1898:
1894:
1893:
1891:
1890:
1885:
1879:
1877:
1870:
1864:
1863:
1860:
1859:
1857:
1856:
1850:
1845:
1843:Gyratum repens
1840:
1835:
1829:
1823:
1821:
1817:
1816:
1814:
1813:
1808:
1803:
1798:
1793:
1788:
1782:
1780:
1776:
1775:
1773:
1772:
1767:
1765:Toxic erythema
1762:
1757:
1755:Drug eruptions
1751:
1749:
1742:
1731:
1724:
1716:
1715:
1712:
1711:
1709:
1708:
1703:
1698:
1693:
1688:
1683:
1678:
1673:
1667:
1665:
1661:
1660:
1658:
1657:
1652:
1647:
1642:
1637:
1632:
1627:
1622:
1617:
1611:
1609:
1603:
1602:
1600:
1599:
1594:
1592:Lichen nitidus
1589:
1584:
1579:
1574:
1569:
1564:
1559:
1553:
1551:
1545:
1544:
1542:
1541:
1536:
1531:
1526:
1521:
1516:
1511:
1506:
1501:
1496:
1494:Herpes simplex
1490:
1488:
1482:
1481:
1479:
1478:
1473:
1468:
1463:
1458:
1453:
1448:
1443:
1437:
1432:
1427:
1422:
1416:
1410:
1408:
1402:
1401:
1399:
1398:
1393:
1388:
1383:
1378:
1373:
1368:
1363:
1358:
1353:
1348:
1343:
1337:
1335:
1328:
1317:
1311:
1310:
1307:
1306:
1304:
1303:
1298:
1293:
1288:
1283:
1278:
1273:
1268:
1263:
1258:
1253:
1248:
1243:
1237:
1235:
1226:
1225:
1223:
1222:
1217:
1212:
1207:
1202:
1196:
1194:
1190:
1189:
1187:
1186:
1181:
1176:
1171:
1166:
1161:
1156:
1151:
1146:
1141:
1136:
1130:
1128:
1119:
1115:
1114:
1109:
1108:
1101:
1094:
1086:
1080:
1079:
1065:
1064:
1061:
1060:
1049:
1038:
1019:
998:
993:
992:
990:
989:Classification
982:
981:External links
979:
976:
975:
956:
937:(7): 759–760.
921:
907:10.1086/320721
900:(12): 1810–4.
894:J. Infect. Dis
880:
873:
855:
842:
807:
782:Ann Intern Med
771:
737:
665:
634:
617:10.1086/508667
590:
579:(5): 283–291.
559:
530:(3): 564–567.
510:
477:
437:
391:
339:
305:
304:
302:
299:
297:skin lesions.
262:Arvid Afzelius
257:
254:
241:
238:
218:
215:
169:
162:
161:
157:
150:
149:
148:
147:
146:
144:
141:
132:
129:
125:
124:
114:
107:
105:
98:
91:
88:
87:
86:
26:
9:
6:
4:
3:
2:
3042:
3031:
3028:
3026:
3023:
3021:
3018:
3017:
3015:
2996:
2993:
2991:
2988:
2986:
2983:
2981:
2978:
2976:
2973:
2971:
2968:
2967:
2965:
2963:
2958:
2952:
2949:
2947:
2944:
2942:
2939:
2937:
2934:
2932:
2929:
2928:
2926:
2924:
2920:
2914:
2911:
2908:
2904:
2903:
2899:
2897:
2894:
2892:
2889:
2887:
2884:
2882:
2879:
2878:
2876:
2874:
2873:drug eruption
2869:
2865:
2862:
2860:
2856:
2846:
2843:
2841:
2838:
2837:
2835:
2833:
2829:
2823:
2820:
2818:
2815:
2813:
2810:
2808:
2805:
2803:
2800:
2798:
2795:
2793:
2790:
2788:
2785:
2784:
2782:
2778:
2768:
2765:
2763:
2760:
2758:
2755:
2753:
2750:
2748:
2745:
2743:
2740:
2739:
2736:
2730:
2727:
2725:
2722:
2720:
2717:
2716:
2713:
2707:
2704:
2702:
2699:
2697:
2694:
2690:
2687:
2686:
2685:
2682:
2681:
2678:
2675:
2673:
2669:
2663:
2660:
2659:
2657:
2653:
2650:
2647:
2643:
2638:
2634:
2625:
2620:
2618:
2613:
2611:
2606:
2605:
2602:
2589:
2585:
2581:
2580:
2576:
2575:
2572:
2571:
2567:
2565:
2564:
2560:
2557:
2553:
2552:
2548:
2547:
2545:
2543:
2539:
2533:
2532:
2528:
2526:
2525:
2521:
2519:
2518:
2514:
2512:
2511:
2507:
2505:
2504:
2500:
2499:
2497:
2495:
2491:
2479:
2476:
2474:
2471:
2469:
2466:
2465:
2464:
2463:
2459:
2458:
2455:
2454:
2450:
2447:
2443:
2442:
2438:
2437:
2435:
2433:
2432:
2427:
2424:
2422:
2418:
2403:
2402:Leptospirosis
2399:
2398:
2394:
2393:
2391:
2389:
2388:
2383:
2380:
2378:
2374:
2363:
2359:
2358:
2353:
2352:
2347:
2346:
2342:
2339:
2335:
2334:
2330:
2329:
2324:
2321:
2319:
2316:
2314:
2311:
2310:
2309:
2308:
2303:
2302:
2298:
2297:
2295:
2293:
2292:
2287:
2281:
2280:
2276:
2273:
2269:
2268:
2264:
2260:
2257:
2255:
2251:
2248:
2247:
2246:
2245:
2241:
2240:
2238:
2236:
2235:
2230:
2227:
2225:
2221:
2218:
2216:
2215:Spirochaetota
2212:
2207:
2203:
2199:
2198:gram negative
2195:
2188:
2183:
2181:
2176:
2174:
2169:
2168:
2165:
2149:
2146:
2144:
2141:
2139:
2136:
2134:
2131:
2129:
2126:
2124:
2121:
2119:
2116:
2114:
2111:
2109:
2106:
2104:
2103:Lichen planus
2101:
2099:
2096:
2094:
2091:
2090:
2088:
2086:
2080:
2074:
2071:
2069:
2066:
2064:
2061:
2059:
2058:Onychomycosis
2056:
2055:
2053:
2051:
2047:
2041:
2038:
2036:
2033:
2031:
2028:
2026:
2023:
2021:
2020:Tinea capitis
2018:
2016:
2013:
2011:
2008:
2006:
2003:
2001:
1998:
1997:
1995:
1991:
1985:
1984:
1982:
1980:
1976:
1973:
1969:Miscellaneous
1967:
1953:
1950:
1948:
1945:
1943:
1940:
1938:
1934:
1931:
1930:
1928:
1924:
1910:
1907:
1905:
1902:
1901:
1899:
1895:
1889:
1886:
1884:
1881:
1880:
1878:
1874:
1871:
1867:Nonblanchable
1865:
1854:
1851:
1849:
1846:
1844:
1841:
1839:
1836:
1834:
1830:
1828:
1825:
1824:
1822:
1818:
1812:
1809:
1807:
1804:
1802:
1799:
1797:
1794:
1792:
1789:
1787:
1784:
1783:
1781:
1777:
1771:
1768:
1766:
1763:
1761:
1758:
1756:
1753:
1752:
1750:
1746:
1743:
1741:
1735:
1732:
1728:
1725:
1717:
1707:
1704:
1702:
1699:
1697:
1694:
1692:
1689:
1687:
1684:
1682:
1679:
1677:
1674:
1672:
1669:
1668:
1666:
1664:Hypopigmented
1662:
1656:
1653:
1651:
1648:
1646:
1643:
1641:
1638:
1636:
1633:
1631:
1628:
1626:
1623:
1621:
1618:
1616:
1615:Acne vulgaris
1613:
1612:
1610:
1608:
1604:
1598:
1595:
1593:
1590:
1588:
1585:
1583:
1580:
1578:
1575:
1573:
1570:
1568:
1567:Lichen planus
1565:
1563:
1560:
1558:
1555:
1554:
1552:
1550:
1546:
1540:
1537:
1535:
1532:
1530:
1527:
1525:
1522:
1520:
1517:
1515:
1512:
1510:
1507:
1505:
1502:
1500:
1499:Herpes zoster
1497:
1495:
1492:
1491:
1489:
1487:
1483:
1477:
1474:
1472:
1471:Parapsoriasis
1469:
1467:
1464:
1462:
1459:
1457:
1454:
1452:
1449:
1447:
1444:
1441:
1438:
1436:
1433:
1431:
1428:
1426:
1423:
1421:
1417:
1415:
1412:
1411:
1409:
1407:
1403:
1397:
1394:
1392:
1389:
1387:
1384:
1382:
1379:
1377:
1374:
1372:
1369:
1367:
1364:
1362:
1359:
1357:
1354:
1352:
1349:
1347:
1344:
1342:
1339:
1338:
1336:
1332:
1329:
1321:
1318:
1316:
1312:
1302:
1299:
1297:
1294:
1292:
1289:
1287:
1284:
1282:
1279:
1277:
1274:
1272:
1269:
1267:
1264:
1262:
1259:
1257:
1254:
1252:
1249:
1247:
1244:
1242:
1239:
1238:
1236:
1231:
1227:
1221:
1218:
1216:
1213:
1211:
1208:
1206:
1203:
1201:
1198:
1197:
1195:
1191:
1185:
1182:
1180:
1177:
1175:
1172:
1170:
1167:
1165:
1162:
1160:
1157:
1155:
1152:
1150:
1147:
1145:
1142:
1140:
1137:
1135:
1132:
1131:
1129:
1127:
1123:
1120:
1116:
1107:
1102:
1100:
1095:
1093:
1088:
1087:
1084:
1078:
1077:
1073:
1070:
1069:
1059:
1055:
1054:
1050:
1048:
1044:
1043:
1039:
1037:
1033:
1029:
1028:
1024:
1020:
1017:
1013:
1009:
1008:
1004:
1000:
999:
996:
991:
987:
971:
967:
960:
952:
948:
944:
940:
936:
932:
931:South. Med. J
925:
917:
913:
908:
903:
899:
895:
891:
884:
876:
870:
866:
859:
852:
846:
838:
834:
830:
826:
823:(2): 239–60.
822:
818:
811:
803:
799:
795:
791:
787:
783:
775:
767:
763:
759:
755:
751:
744:
742:
730:
726:
722:
717:
712:
708:
704:
700:
696:
689:
682:
680:
678:
676:
674:
672:
670:
661:
657:
653:
649:
645:
638:
631:
627:
623:
618:
613:
609:
605:
601:
594:
586:
582:
578:
574:
570:
563:
555:
551:
546:
541:
537:
533:
529:
525:
521:
514:
498:
494:
488:
486:
484:
482:
473:
469:
465:
461:
457:
453:
446:
444:
442:
433:
429:
425:
421:
417:
413:
406:
404:
402:
400:
398:
396:
387:
383:
379:
375:
370:
365:
361:
357:
353:
346:
344:
327:
325:
319:
313:
311:
306:
298:
296:
292:
288:
284:
278:
276:
272:
269:
268:
263:
253:
251:
247:
237:
235:
231:
223:
214:
210:
202:
198:
196:
192:
188:
184:
180:
166:
154:
140:
138:
137:target lesion
121:
117:
111:
106:
102:
101:"bull's eye,"
95:
90:
89:
85:
83:
79:
78:
72:
68:
64:
60:
56:
52:
48:
44:
40:
33:
19:
3030:Spirochaetes
3025:Lyme disease
2980:Erythroderma
2940:
2902:panniculitis
2900:
2577:
2568:
2561:
2549:
2529:
2522:
2515:
2508:
2501:
2494:Bacteroidota
2460:
2451:
2439:
2429:
2395:
2385:
2355:
2349:
2343:
2331:
2317:
2313:Lyme disease
2305:
2299:
2289:
2277:
2265:
2242:
2232:
2073:Ingrown nail
1645:Dermatophyte
1640:Gonococcemia
1625:Folliculitis
1266:Neurofibroma
1234:subcutaneous
1074:
1051:
1040:
1021:
1001:
969:
965:
959:
934:
930:
924:
897:
893:
883:
864:
858:
850:
845:
820:
816:
810:
788:(6): 421–8.
785:
781:
774:
757:
753:
729:the original
698:
694:
651:
647:
637:
629:
607:
603:
593:
576:
572:
562:
527:
523:
513:
501:. Retrieved
497:Lyme Disease
496:
455:
451:
419:
415:
359:
355:
329:. Retrieved
321:
295:erythematous
279:
265:
259:
243:
228:
211:
207:
191:back of knee
176:
143:Presentation
134:
131:Lyme disease
119:
115:
100:
76:
59:Lyme disease
50:
46:
45:
43:
2446:Psittacosis
2421:Chlamydiota
2128:Herpesvirus
2108:Leukoplakia
1933:Scleroderma
1820:Specialized
1748:Generalized
1723:involvement
1635:Candidiasis
1327:involvement
1301:Myxoid cyst
1149:Acrochordon
865:Dermatology
654:(1): 1–19.
283:spirochetal
250:doxycycline
246:antibiotics
3014:Categories
2832:Angioedema
2387:Leptospira
2068:Paronychia
1909:Vasculitis
1833:Multiforme
1831:Erythema (
1786:Cellulitis
1737:Blanchable
1486:Blistering
1476:Ichthyosis
1334:Eczematous
1246:Hemangioma
1053:DiseasesDB
760:(6): 424,
301:References
275:meningitic
2637:Urticaria
2468:Chlamydia
2431:Chlamydia
2234:Treponema
2063:Psoriasis
1971:disorders
1926:Indurated
1827:Urticaria
1779:Localized
1721:epidermal
1504:Varicella
1414:Psoriasis
1325:epidermal
1291:Leiomyoma
1193:Pigmented
1126:Epidermal
1072:DermAtlas
378:1058-4838
331:6 October
240:Treatment
193:, on the
82:Neo-Latin
67:tick bite
2962:erythema
2859:Erythema
2689:Familial
2478:Trachoma
2291:Borrelia
2250:Syphilis
2138:Syphilis
2085:membrane
1740:Erythema
1676:Vitiligo
1630:Impetigo
1607:Pustular
1572:Miliaria
1420:Corporis
1271:Xanthoma
1220:Melanoma
1200:Freckles
951:18580719
916:11372036
837:11982300
802:11900494
766:24818260
725:24785207
660:18290267
626:17029130
585:30216021
554:38407256
545:10902532
503:18 April
472:17579230
432:Archived
428:22962880
386:28605419
234:erythema
77:Borrelia
69:. This
2646:chronic
2196:due to
1937:morphea
1897:Papular
1876:Macular
1869:Purpura
1853:Ab igne
1838:Migrans
1791:Abscess
1719:Without
1701:Leprosy
1620:Rosacea
1557:Scabies
1549:Papular
1418:Tinea (
1406:Scaling
1210:Melasma
1205:Lentigo
1118:Growths
1047:D015787
1018:A69.22)
716:4487875
256:History
2960:Other
2083:Mucous
1979:Ulcers
1440:Faciei
1435:Manuum
1425:Cruris
1315:Rashes
1261:Lipoma
1256:Keloid
1230:Dermal
1139:Callus
1032:088.81
949:
914:
871:
835:
800:
764:
723:
713:
658:
624:
583:
552:
542:
470:
426:
384:
376:
267:Ixodes
183:armpit
2642:acute
2272:Pinta
2254:bejel
1430:Pedis
1215:Nevus
1036:529.1
1012:A69.2
732:(PDF)
691:(PDF)
326:(CDC)
322:U.S.
195:trunk
189:, or
187:groin
2259:Yaws
2200:non-
2050:Nail
1993:Hair
1796:Boil
1323:With
1134:Wart
1058:4439
1042:MeSH
1027:9-CM
1016:ILDS
947:PMID
912:PMID
869:ISBN
833:PMID
798:PMID
762:PMID
721:PMID
656:PMID
622:PMID
581:PMID
550:PMID
505:2019
468:PMID
452:JAMA
424:PMID
382:PMID
374:ISSN
333:2017
271:tick
179:rash
71:rash
55:rash
2206:BV4
1730:Red
1232:and
1076:208
1023:ICD
1003:ICD
939:doi
935:101
902:doi
898:183
825:doi
790:doi
786:136
711:PMC
703:doi
699:370
612:doi
540:PMC
532:doi
460:doi
456:297
364:doi
49:or
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1034:,
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