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Fecal occult blood

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598:. FIT screening is more effective in terms of health outcomes and cost compared with guaiac FOBT. According to the guidelines of the American College of Gastroenterology, "Annual fecal immunochemical testing is the preferred colorectal cancer detection test." A FIT test detects globin levels in feces at or above 50 nanograms per mL, the established cutoff by the World Health Organization for Colorectal Cancer Screening. FIT testing has replaced most gFOBT tests as the colon cancer screening test of choice. This methodology can be adapted for automated test reading and to report quantitative results, which are potential factors in design of a widescale screening strategy. The number of fecal samples submitted for FIT may affect the clinical sensitivity and specificity of the methodology. High-sensitivity gFOBT tests such as Hemoccult SENSA remain an accepted option and may retain a role in monitoring gastrointestinal conditions such as ulcerative colitis; however, the FIT test is preferred in recent guidelines. FIT is widely used outside of the US, and generally cost less than US$ 20 per test in 2020, compared to US$ 1,000 or more for a colonoscopy. 317:(USPSTF)'s 2016 recommendation, instead of emphasizing specific screening approaches, has instead chosen to highlight that there is convincing evidence that colorectal cancer screening substantially reduces deaths from the disease among adults aged 50 to 75 years and that not enough adults are using this effective preventive intervention. The ACG and MSTF also included CT colonography every five years, and fecal DNA testing as considerations. All three recommendation panels recommended replacing any older low-sensitivity, guaiac-based fecal occult blood testing (gFOBT) with either newer high-sensitivity guaiac-based fecal occult blood testing (hs gFOBT) or fecal immunochemical testing (FIT). MSTF looked at six studies that compared high-sensitivity gFOBT (Hemoccult SENSA) to FIT, and concluded that there was no clear difference in overall performance between these methods. 644:-like effect, rapidly breaking down hydrogen peroxide. In some settings such as gastric or proximal upper intestinal bleeding, the guaiac method may be more sensitive than tests detecting globin because globin is broken down in the upper intestine to a greater extent than is heme. There are various commercially available gFOBT tests which have been categorized as being of low or high sensitivity, and only high-sensitivity tests remain an acceptable alternative to FIT testing, which is now the best-practices recommendation in colon cancer screening. Optimal clinical performance of the 336: 603: 474:. It is sometimes performed with chromoendoscopy, a method that assists the endoscopist by enhancing the visual difference between cancerous and normal tissue, by either marking the abnormally increased DNA content (toluidine blue) or failing to stain the tumor, possibly due to decreased surface glycogen on tumor cells(Lugol). Infrared fluorescent endoscopy and ultrasonic endoscopy can interrogate vascular abnormalities such as esophageal varices. 690: 324:(NHS) introduced a Bowel Cancer Screening Program in 2006. It is now offered to patients aged 60–74 years. In 2019 FIT was introduced as the primary screening test in England and Wales, replacing gFOBt. However, research carried out in the UK has suggested that the FIT threshold for further investigation is set at a point that may miss more than half of bowel cancer cases and only identifies one in four high-risk polyps. 25: 117: 139: 788:
gastrointestinal tract than alternatives. The detection rate of the test decreases if the time from sample collection to laboratory processing is delayed; processing the sample in under five days from collection is recommended. It does not appear to be affected by aspirin, anticoagulants, or nonsteroidal anti-inflammatory drugs.
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vomiting, abdominal pain, diarrhea and gastrointestinal bleeding. Approximately one third of endurance runners experience transient but exercise-limiting symptoms, and repetitive gastrointestinal bleeding occasionally causes iron deficiency and anaemia. Runners can sometimes experience significant symptoms including
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Multi-Society Task Force (MSTF)'s recommended first-tier tests are a colonoscopy every 10 years or annual FIT test. If FIT is utilized, proper steps must be taken to ensure appropriate use and follow-up of abnormal FIT results. FIT tests however are not that useful in picking up adenomas, even when advanced.
504:. Exercise is associated with extensive changes in gastrointestinal (GI) tract physiology, including diversion of blood flow from the GI tract to muscles and lungs, decreased GI absorption and small intestinal motility, increased colonic transit, neuroimmunoendocrine changes in hormones and peptides such as 754:
including 51-chromium studies, analytical recovery studies in spiked stool samples, analytical recovery after ingestion of autologous blood, rarer studies of carefully quantified blood instilled at bowel surgery , as well as other research approaches. Additionally, clinical studies look at a variety
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In 2006, the Australian Government introduced the National Bowel Cancer Program which has been updated several times since; targeted screening will be done of all Australians aged from 50 to 74 by 2020. Cancer Council Australia recommended that FOBT should be done every two years. People over 50 not
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methods for colon cancer depend on detecting either precancerous changes such as certain kinds of polyps or on finding early and thus more treatable cancer. The extent to which screening procedures reduce the risk of gastrointestinal cancer or deaths depends on the rate of precancerous and cancerous
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for hidden (occult) blood in the stool should be used at home following the test kit's directions with spontaneously passed stool or on samples submitted to a clinical laboratory. Testing kits are available at pharmacies in some countries without a prescription, or a health professional may order a
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The American College of Gastroenterology has recommended the abandoning of gFOBT testing as a colorectal cancer screening tool, in favor of the fecal immunochemical test. Though the FIT test is preferred, even the guaiac FOB testing of average risk populations may have been sufficient to reduce the
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result due to exogenous blood and various porphyrins. HemoQuant is the most sensitive test for upper gastrointestinal bleeding and therefore may be most appropriate fecal occult blood test to use in the evaluation of iron deficiency. It is advisable to stop ingesting red meat and aspirin for three
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ml to become positive. The sensitivity of a single-stool guaiac test to pick up bleeding has been quoted at 10 to 30%, but if a standard three tests are done as recommended the sensitivity rises to 92%. Reduced patient compliance with the collection of three samples hampers the usefulness of this
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ml of daily blood in the stool; yet this test threshold does not cause undue false positives from normal upper intestinal blood leakage because it does not detect occult blood from the stomach and upper small intestine. Thus, the FIT test is much more specific for bleeding from the colon or lower
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every ten years in average-risk individuals, beginning at age 50. The ACG suggests that cancer detection tests such as any type of FOB are an alternative that is less preferred, and if a colonoscopy is declined, the FIT (fecal immunochemical test, or iFOBT) should be offered instead. The 2017 US
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Gastrointestinal (GI) complaints and low-intensity GI bleeding frequently occur in marathon runners. Strenuous exercise, particularly in elite athlete runners and less frequently in other exercise activities, can cause acute incapacitating gastrointestinal symptoms including heartburn, nausea,
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The use of an FOBT for bleeding from the mouth, nose, esophagus, lungs, stomach and the initial portion of the small intestine, while the same as fecal testing, is discouraged, due to technical considerations including poorly characterized test performance characteristics such as sensitivity,
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is encouraged over gFOBT for routine screening, as it may pick up tumors whether or not they are bleeding. It is able to detect 80 percent of colorectal cancers and 44 percent for adenoma > 1 centimeter, while gFOBT picks up 13 to 50 percent of colorectal cancers.
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disease in that population. gFOBT (guaiac fecal occult blood test) and flexible sigmoidoscopy screening have each shown benefit. Other colon cancer screening tools such as iFOBT (immunochemical fecal occult blood test) or colonoscopy are also included in guidelines.
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Kewenter J, Brevinge H, Engarås B, Haglind E, Ahrén C (May 1994). "Results of screening, rescreening, and follow-up in a prospective randomized study for detection of colorectal cancer by fecal occult blood testing. Results for 68,308 subjects".
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Walleser S, Griffiths A, Lord SJ, Howard K, Solomon MJ, Gebski V (December 2007). "What is the value of computered tomography colonography in patients screening positive for fecal occult blood? A systematic review and economic evaluation".
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Rex DK, Boland CR, Dominitz JA, Giardiello FM, Johnson DA, Kaltenbach T, et al. (July 2017). "Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer".
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Nieuwenburg SA, Vuik FE, Kruip MJ, Kuipers EJ, Spaander MC (May 2019). "Effect of anticoagulants and NSAIDs on accuracy of faecal immunochemical tests (FITs) in colorectal cancer screening: a systematic review and meta-analysis".
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Bardhan PK, Beltinger J, Beltinger RW, Hossain A, Mahalanabis D, Gyr K (January 2000). "Screening of patients with acute infectious diarrhoea: evaluation of clinical features, faecal microscopy, and faecal occult blood testing".
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Imperiale TF, Gruber RN, Stump TE, Emmett TW, Monahan PO (March 2019). "Performance Characteristics of Fecal Immunochemical Tests for Colorectal Cancer and Advanced Adenomatous Polyps: A Systematic Review and Meta-analysis".
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Collins JF, Lieberman DA, Durbin TE, Weiss DG (January 2005). "Accuracy of screening for fecal occult blood on a single stool sample obtained by digital rectal examination: a comparison with recommended sampling practice".
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specificity, and analytical interference. However, chemical confirmation that coloration is due to blood rather than coffee, beets, medications, or food additives can be of significant clinical assistance.
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Bevan R, Lee TJ, Nickerson C, Rubin G, Rees CJ (June 2014). "Non-neoplastic findings at colonoscopy after positive faecal occult blood testing: data from the English Bowel Cancer Screening Programme".
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mg of cimetidine 1 hr before the start and again at 50 miles of a 100-mile running race substantially decreased GI symptoms and post-race guaiac test positivity but did not affect race performance.
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Harewood GC, McConnell JP, Harrington JJ, Mahoney DW, Ahlquist DA (January 2002). "Detection of occult upper gastrointestinal tract bleeding: performance differences in fecal occult blood tests".
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Hardcastle JD, Chamberlain JO, Robinson MH, Moss SM, Amar SS, Balfour TW, et al. (November 1996). "Randomised controlled trial of faecal-occult-blood screening for colorectal cancer".
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recommends that men and women aged 50 and over have an FOBT at least every two years. In colon cancer screening, using only one sample of feces collected by a doctor performing a
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Sheng JQ, Li SR, Su H, Li JS, Sun ZQ, Wu ZT, et al. (June 2010). "Fecal cytology in conjunction with immunofecal occult blood test for colorectal cancer screening".
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testing kit for use at home. If a home fecal occult blood test detects blood in the stool it is recommended to see a health professional to arrange further testing.
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and peptide-histidine-methionine. Substantial changes occur in stress hormones including cortisol, in circulating concentrations and metabolic behavior of various
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ml of blood escapes blood vessels into the stool each day. Significant amounts of blood can be lost without producing visible blood in the stool, estimated as 200
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In the event of a positive fecal occult blood test, the next step in the workup is a form of visualization of the gastrointestinal tract by one of several means:
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Kronborg O, Fenger C, Olsen J, Jørgensen OD, Søndergaard O (November 1996). "Randomised study of screening for colorectal cancer with faecal-occult-blood test".
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two hours before running a marathon did not significantly affect the frequency of gastrointestinal symptoms or occult gastrointestinal bleeding. Conversely, 800
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for fecal occult blood (gFOBT) sensitivity varies depending on the site of bleeding. Moderately sensitive gFOBT can pick up a daily blood loss of about 10
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Whitlock EP, Lin J, Liles E, Beil T, Fu R, O'Connor E, Thompson RN, Cardenas T (2008). "Screening for Colorectal Cancer: An Updated Systematic Review".
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The American College of Gastroenterology has recommended the abandoning of gFOBT testing as a colorectal cancer screening tool, in favor of the
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Moses FM, Baska RS, Peura DA, Deuster PA (October 1991). "Effect of cimetidine on marathon-associated gastrointestinal symptoms and bleeding".
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An estimated 1–5% of large tested populations have a positive fecal occult blood test. Of those, about 2–10% have cancer, while 20–30% have
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Ahlquist DA, McGill DB, Schwartz S, Taylor WF, Owen RA (May 1985). "Fecal blood levels in health and disease. A study using HemoQuant".
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days prior to specimen collection. False positives can occur with myoglobin, catalase, or protohemes and in certain types of porphyria.
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Schiff L, Stevens RJ, Shapiro N, et al. Observations on the oral administration of citrate blood in man. Am J Med Sci 1942; 203: 409.
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Endo M, Takeshita K, Yoshida M (September 1986). "How can we diagnose the early stage of esophageal cancer? Endoscopic diagnosis".
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has many potential sources, and positive results usually result in further testing for the bleeding site, usually looking for
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test. Further discussion of sensitivity and specificity issues that relate particularly to the guaiac method is found in the
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St John DJ, Young GP (April 1978). "Evaluation of radiochromium blood loss studies in unexplained iron-deficiency anaemia".
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may have unintentionally decreased digital rectal examination and FOBT in hospital settings such as Emergency Departments.
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There are four methods in clinical use to test for occult blood in feces. These look at different properties, such as
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Dybdahl JH, Daae LN, Larsen S (1981). "Occult faecal blood loss determined by chemical tests and a 51 Cr method".
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ml in the duodenum, and lesser amounts in the lower intestine. Tests for occult blood identify lesser blood loss.
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by about 25%. With this lower efficacy, it was not always cost-effective to screen a large population with gFOBT.
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causes unless there are other clues. Colonoscopy is usually preferred to computerized tomographic colonography.
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de Oliveira EP, Burini RC (September 2009). "The impact of physical exercise on the gastrointestinal tract".
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Endo M, Sakakibara N, Suzuki H (1972). "Observation of esophageal lesions with the use of endoscopic dyes".
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Young GP, Cole SR (March 2009). "Which fecal occult blood test is best to screen for colorectal cancer?".
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ml (about two teaspoonfuls), and higher sensitivity gFOBT can pick up lesser amounts, requires at least 2
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expression. Symptoms can be exacerbated by dehydration or by pre-exercise ingestion of certain foods and
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van Rossum LG, van Rijn AF, van Oijen MG, Fockens P, Laheij RJ, Verbeek AL, et al. (August 2009).
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Brouns F, Beckers E (April 1993). "Is the gut an athletic organ? Digestion, absorption and exercise".
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Robertson DJ, Lee JK, Boland CR, Dominitz JA, Giardiello FM, Johnson DA, et al. (April 2017).
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Harewood GC, Ahlquist DA (2000). "Fecal occult blood testing for iron deficiency: a reappraisal".
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Venkatraman JT, Pendergast DR (2002). "Effect of dietary intake on immune function in athletes".
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Fecal occult blood testing (FOBT), as its name implies, aims to detect subtle blood loss in the
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involves smearing some feces onto some absorbent paper that has been treated with a chemical.
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Halvorsen FA, Lyng J, Ritland S (May 1986). "Gastrointestinal bleeding in marathon runners".
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The estimates for test performance characteristics are based on comparison with a variety of
335: 2372:"Cimetidine reduces running-associated gastrointestinal bleeding. A prospective observation" 1705: 1233:"The NHS Bowel Cancer Screening Program: current perspectives on strategies for improvement" 50: 5009: 4994: 4963: 4491: 4004: 3994: 3933: 3886: 3869: 3788: 3629: 3500: 1740:"Faecal pyruvate kinase isoenzyme type M2 for colorectal cancer screening: a meta-analysis" 831: 294: 274: 198:). A fecal occult blood test (FOBT) checks for hidden (occult) blood in the stool (feces). 1972:"Fecal Occult Blood Testing in Hospitalized Patients with Upper Gastrointestinal Bleeding" 1371:
Li SJ, Sharples LD, Benton SC, Blyuss O, Mathews C, Sasieni P, Duffy SW (September 2021).
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are present, the paper will change color in one or two seconds. This method works as the
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Mandel JS, Bond JH, Church TR, Snover DC, Bradley GM, Schuman LM, Ederer F (May 1993).
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including fact sheets in 24 languages at Ontario Ministry of Health and Long-Term Care
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If colon cancer is suspected in an individual (such as in someone with an unexplained
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yet eligible for the national program can arrange with their doctor for an FOBT. The
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Rex DK, Johnson DA, Anderson JC, Schoenfeld PS, Burke CA, Inadomi JM (March 2009).
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Fecal DNA tests as of 2008 had not been studied enough to support widespread use.
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for that disease. It can also be used to look for active occult blood loss in
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Kuriyama M, Kato J, Takemoto K, Hiraoka S, Okada H, Yamamoto K (March 2010).
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Additional methods of looking for occult blood are being explored, including
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Peters HP, De Vries WR, Vanberge-Henegouwen GP, Akkermans LM (March 2001).
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Bretthauer M (August 2010). "Evidence for colorectal cancer screening".
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if you can. Unsourced or poorly sourced material may be challenged and
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from cellular material such as from lesions of the intestinal mucosa.
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Sheng JQ, Li SR, Wu ZT, Xia CH, Wu X, Chen J, Rao J (August 2009).
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Mathews B, Ratcliffe T, Sehgal R, Abraham J, Monash B (July 2017).
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Fecal immunochemical testing (FIT) can identify as little as 0.3
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Rockey DC (December 2005). "Occult gastrointestinal bleeding".
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look for DNA alterations that have been associated with cancer.
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Adams BD, McHugh KJ, Bryson SA, Dabulewicz J (February 2008).
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Schwartz S, Dahl J, Ellefson M, Ahlquist D (December 1983).
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Rockey DC (July 1999). "Occult gastrointestinal bleeding".
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Nature Clinical Practice. Gastroenterology & Hepatology
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Burt RW (September 2010). "Colorectal cancer screening".
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Current Opinion in Clinical Nutrition and Metabolic Care
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Cards and bottle used for the Hemoccult test, a type of
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Tonus C, Sellinger M, Koss K, Neupert G (August 2012).
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Best Practice & Research. Clinical Gastroenterology
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Koo S, Neilson LJ, Von Wagner C, Rees CJ (2017-12-04).
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Berchi C, Bouvier V, Réaud JM, Launoy G (March 2004).
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A positive traditional guaiac fecal occult blood test
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A LabCorp fecal occult blood immunoassay testing kit.
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is then dropped onto the paper; if trace amounts of
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that is not visibly apparent (unlike other types of
3185: 1332:"New pathways could improve bowel cancer screening" 2766:Analytical and Quantitative Cytology and Histology 2825: 2369: 2045: 205:(FIT). The newer and recommended tests look for 4986: 2729:Cancer Epidemiology, Biomarkers & Prevention 1212:. U.S. Preventive Services Task Force. June 2016 941: 648:depends on preparatory dietary adjustment. The 3186:Cleveland NJ, Yaron M, Ginde AA (August 2010). 2456:http://patients.gi.org/topics/colorectal-cancer 2448: 2415: 2413: 1676: 1674: 851:Beg M, Singh M, Saraswat MK, Rewari BB (2002). 485: 16:Blood in the feces that is not visibly apparent 2863:Australian and New Zealand Journal of Medicine 2370:Baska RS, Moses FM, Deuster PA (August 1990). 2226: 2224: 758: 284: 49:Please review the contents of the article and 4691:Transjugular intrahepatic portosystemic shunt 4092: 4051: 3407: 2230: 481:: a series of x-rays of the colon and rectum. 281:or when there are gastrointestinal symptoms. 3179: 3140: 3117: 3023: 2918: 2860: 2757: 2722: 2716: 2678:"Diagnostic Tests — Fecal Occult Blood Test" 2551: 2510: 2467: 2410: 2267: 2082: 2039: 1860: 1858: 1856: 1817: 1782: 1671: 1413: 528:liquids, and lessened by adequate training. 370: 315:United States Preventive Services Task Force 3076: 2763: 2363: 2320: 2221: 2004: 1105: 978: 935: 718:. Unsourced material may be challenged and 4341: 4058: 4044: 3414: 3400: 3126:Agency for Healthcare Research and Quality 1733: 1731: 1419: 137: 4832: 3203: 3100: 2942: 2740: 2585: 2575: 2534: 2473: 2287: 2212: 2163: 2137: 2114: 1987: 1853: 1791:Gastroenterology Clinics of North America 1765: 1755: 1695: 1472: 1396: 1258: 1248: 1177: 1131: 1046: 910: 738:Learn how and when to remove this message 4497:Transanal hemorrhoidal dearterialization 2828:Scandinavian Journal of Gastroenterology 2419: 2013:Scandinavian Journal of Gastroenterology 1827:Clinical Gastroenterology and Hepatology 1593:Scandinavian Journal of Gastroenterology 988:Scandinavian Journal of Gastroenterology 899:The American Journal of Gastroenterology 814:quantification by HemoQuant can yield a 601: 334: 4654:Artificial extracorporeal liver support 3070:Mayo Clinic: Mayo Clinical Laboratories 1728: 1706:10.7326/0003-4819-142-2-200501180-00006 4987: 2641: 2611:"A Colonoscopy Alternative Comes Home" 2186: 1788: 830:Safety regulations from US accreditor 679: 584:immunochemical fecal occult blood test 253:and warrant further investigation for 4039: 3395: 1237:Risk Management and Healthcare Policy 269:). The test does not directly detect 4209:Vertical banded gastroplasty surgery 3254: 2608: 1112:Journal of General Internal Medicine 779:Clinical sensitivity and specificity 716:adding citations to reliable sources 683: 303:American College of Gastroenterology 18: 4258:Percutaneous endoscopic gastrostomy 4066:Tests and procedures involving the 3257:Current Opinion in Gastroenterology 2793:The New England Journal of Medicine 2644:The New England Journal of Medicine 1461:The New England Journal of Medicine 674: 494: 213:, or other blood factors including 13: 4696:Distal splenorenal shunt procedure 2875:10.1111/j.1445-5994.1978.tb04496.x 2140:"Educational Case: Diverticulosis" 763:In healthy people about 0.5 to 1.5 14: 5021: 3224: 3205:10.1016/j.annemergmed.2009.12.021 3165:10.1016/j.annemergmed.2007.07.022 2564:World Journal of Gastroenterology 1744:World Journal of Gastroenterology 1653:"Screening for colorectal cancer" 1283:"CKS is only available in the UK" 1106:Cusumano VT, May FP (June 2020). 590:). FIT products utilize specific 2703:"Fecal Occult Blood Test (FOBT)" 2298:10.2165/00007256-200232050-00004 2245:10.2165/00007256-199315040-00003 2138:Toy KA, Conran RM (2022-01-01). 1627:"Bowel cancer screening program" 873:from the original on 2010-11-22. 688: 522:major histocompatibility complex 389:A positive test can result from 115: 23: 4487:Lateral internal sphincterotomy 3136:. Report No.: 08-05-05124-EF-1. 3058: 3003: 2959: 2931:International Journal of Cancer 2898: 2889: 2854: 2819: 2784: 2695: 2670: 2635: 2602: 2434:10.1016/j.gastrohep.2009.01.179 2422:Gastroenterologia y Hepatologia 2420:Quintero E (October 2009). "". 2376:Digestive Diseases and Sciences 2329:Digestive Diseases and Sciences 2180: 2131: 1963: 1920: 1910:Progress of Digestive Endoscopy 1901: 1645: 1619: 1583: 1540: 1497: 1448: 1364: 1324: 1299: 1275: 1224: 395:lower gastrointestinal bleeding 391:upper gastrointestinal bleeding 384:upper gastrointestinal bleeding 380:lower gastrointestinal bleeding 251:lower gastrointestinal bleeding 247:upper gastrointestinal bleeding 228: 4194:Endoscopic sleeve gastroplasty 4145:Functional Lumen Imaging Probe 3066:"Test ID: HQ HemoQuant, Feces" 1202: 1148: 1099: 1063: 1022: 844: 546: 273:but is often used in clinical 51:add the appropriate references 1: 4576:Lower gastrointestinal series 4320:Upper gastrointestinal series 2742:10.1158/1055-9965.EPI-09-0309 1561:10.1016/S0140-6736(96)03430-7 1518:10.1016/S0140-6736(96)03386-7 837: 825: 506:vasoactive intestinal peptide 4842:Diagnostic peritoneal lavage 4561:Double-contrast barium enema 4388:Partial ileal bypass surgery 4265:Esophagogastric dissociation 3269:10.1097/MOG.0b013e32833d1733 3192:Annals of Emergency Medicine 3153:Annals of Emergency Medicine 2156:10.1016/j.acpath.2022.100014 2060:10.1097/MCO.0b013e32832e6776 1976:Journal of Hospital Medicine 1867:Journal of Medical Screening 1377:Journal of Medical Screening 1085:10.1053/j.gastro.2017.05.013 1048:10.1053/j.gastro.2016.08.053 576:Fecal immunochemical testing 486:Testing secretions for blood 7: 5000:Diagnostic gastroenterology 4659:Bioartificial liver devices 4586:Transrectal ultrasonography 3635:Charcot's cholangitis triad 3102:10.1093/clinchem/29.12.2061 2805:10.1056/NEJM198505303122204 2656:10.1056/NEJM199907013410107 1684:Annals of Internal Medicine 1474:10.1056/NEJM199305133281901 1158:Annals of Internal Medicine 1079:(1). Elsevier BV: 307–323. 759:Gastrointestinal blood loss 285:Colorectal cancer screening 36:reliable medical references 10: 5026: 4581:Small-bowel follow-through 4449:Abdominoperineal resection 4308:Esophagogastroduodenoscopy 2981:10.1136/gutjnl-2018-316344 1833:(12): 1439–46, quiz 1368. 1124:10.1007/s11606-020-05728-y 1000:10.1080/003655200750024533 433:Inflammatory bowel disease 357:digital rectal examination 328:mortality associated with 4941:Clinical prediction rules 4939: 4907: 4875: 4847:Intraperitoneal injection 4823: 4781: 4706: 4644: 4635: 4599: 4551:Abdominal ultrasonography 4505: 4467: 4459:Total mesorectal excision 4439: 4401: 4378:Intestine transplantation 4332: 4293: 4168:Sengstaken–Blakemore tube 4158: 4150:High resolution manometry 4140:Esophageal motility study 4101: 4083: 4074: 4020:Sister Mary Joseph nodule 3942: 3919: 3857: 3824: 3781: 3738: 3731: 3674: 3596: 3437: 3365: 3295: 2840:10.3109/00365528109181963 2205:10.1136/bmj.288.6410.65-b 2025:10.3109/00365528609015168 1839:10.1016/j.cgh.2007.09.003 1803:10.1016/j.gtc.2005.08.010 1605:10.3109/00365529409096840 1434:10.1016/j.bpg.2010.06.005 657:Stool DNA screening tests 397:. The common causes are: 376:Gastrointestinal bleeding 371:Other sources of bleeding 203:fecal immunochemical test 153: 145: 136: 131: 42:or relies too heavily on 4796:Pancreas transplantation 4454:Lower anterior resection 4135:Esophageal pH monitoring 4077:Digestive system surgery 1879:10.1177/0969141314528889 1757:10.3748/wjg.v18.i30.4004 1631:Cancer Council Australia 1389:10.1177/0969141320980501 1307:"Bowel cancer screening" 616:for fecal occult blood ( 4890:Inguinal hernia surgery 4806:Pancreaticoduodenectomy 4189:Adjustable gastric band 4130:Impedance–pH monitoring 3032:Mayo Clinic Proceedings 2577:10.3748/wjg.v16.i9.1110 1657:Canadian Cancer Society 755:of additional factors. 470:Upper gastrointestinal 353:Canadian Cancer Society 322:National Health Service 4920:Exploratory laparotomy 4735:Hepatoportoenterostomy 4199:Gastric bypass surgery 4068:human digestive system 3427:human digestive system 3159:(2): 197–201, 201.e1. 2488:10.1038/ncpgasthep1358 1941:10.1055/s-2007-1018435 1118:(6). JGIM: 1870–1874. 771:ml in the stomach, 100 607: 340: 235:gastrointestinal tract 4895:Femoral hernia repair 4681:Liver transplantation 4275:Nissen fundoplication 3713:Obstructed defecation 2609:Span P (2021-01-11). 605: 338: 217:, while conventional 4492:Rubber band ligation 4431:Hartmann's operation 3975:Aure-Rozanova's sign 3934:Hannington-Kiff sign 3929:Howship–Romberg sign 3887:Aortic insufficiency 3789:Abdominal distension 2107:10.1136/gut.48.3.435 1250:10.2147/RMHP.S109116 912:10.1038/ajg.2009.104 832:the Joint Commission 712:improve this section 423:Diverticular disease 237:, anywhere from the 65:"Fecal occult blood" 4867:Peritoneal dialysis 4686:Portal hypertension 4591:Virtual colonoscopy 4566:Endoanal ultrasound 4482:Anorectal manometry 4477:Anal sphincterotomy 4421:Colonic polypectomy 4216:Collis gastroplasty 3540:Chilaiditi syndrome 1555:(9040): 1467–1471. 1512:(9040): 1472–1477. 1344:10.3310/alert_47581 1041:(5): 1217–1237.e3. 680:Reference standards 667:dipstick and stool 466:Virtual colonoscopy 4361:Jejunoileal bypass 4204:Sleeve gastrectomy 3907:Grey Turner's sign 3837:Hepatosplenomegaly 3766:Abdominal guarding 3698:Fecal occult blood 3689:Fecal incontinence 3660:Mirizzi's syndrome 3570:Sherren's triangle 3423:Signs and symptoms 3366:External resources 3089:Clinical Chemistry 2615:The New York Times 2461:2019-04-19 at the 2454:Colorectal Cancer 2388:10.1007/BF01537243 2341:10.1007/BF01296804 2187:Weaver LT (1984). 2144:Academic Pathology 1935:(Suppl 3): 11–18. 944:Digestive Diseases 608: 444:Sickle cell anemia 416:20–30% adenoma or 341: 219:stool guaiac tests 172:Fecal occult blood 132:Fecal occult blood 4982: 4981: 4927:Rapid urease test 4903: 4902: 4819: 4818: 4811:Puestow procedure 4773:Cholescintigraphy 4631: 4630: 4627: 4626: 4619:Stool guaiac test 4529:Capsule endoscopy 4351:Bariatric surgery 4328: 4327: 4243:Gastroenterostomy 4184:Bariatric surgery 4033: 4032: 4005:Fothergill's sign 3995:Rosenstein's sign 3915: 3914: 3870:Mallet-Guy's sign 3809:Shifting dullness 3630:Courvoisier's law 3389: 3388: 3095:(12): 2061–2067. 2944:10.1002/ijc.24458 2799:(22): 1422–1428. 2335:(10): 1390–1394. 1989:10.12788/jhm.2773 1750:(30): 4004–4011. 1467:(19): 1365–1371. 956:10.1159/000016968 805:stool guaiac test 792:Stool guaiac test 752:reference methods 748: 747: 740: 650:stool guaiac test 646:stool guaiac test 626:Hydrogen peroxide 622:stool guaiac test 613:Stool guaiac test 407:colorectal cancer 263:colorectal cancer 169: 168: 148:stool guaiac test 126:Medical condition 124: 123: 100: 5017: 4964:Child–Pugh score 4931:Urea breath test 4830: 4829: 4791:Frey's procedure 4768:Cholecystography 4642: 4641: 4339: 4338: 4174:Nasogastric tube 4099: 4098: 4090: 4089: 4060: 4053: 4046: 4037: 4036: 3736: 3735: 3723:Rectal discharge 3639:Reynolds' pentad 3578:Radiologic signs 3565:McBurney's point 3439:Gastrointestinal 3425:relating to the 3416: 3409: 3402: 3393: 3392: 3293: 3292: 3288: 3249:ColonCancerCheck 3244:Cleveland Clinic 3218: 3217: 3207: 3183: 3177: 3176: 3144: 3138: 3137: 3121: 3115: 3114: 3104: 3080: 3074: 3073: 3062: 3056: 3055: 3027: 3021: 3020: 3018: 3017: 3007: 3001: 3000: 2963: 2957: 2956: 2946: 2922: 2916: 2915: 2913: 2912: 2902: 2896: 2893: 2887: 2886: 2858: 2852: 2851: 2823: 2817: 2816: 2788: 2782: 2781: 2761: 2755: 2754: 2744: 2735:(8): 2182–2185. 2720: 2714: 2713: 2711: 2710: 2699: 2693: 2692: 2690: 2689: 2680:. Archived from 2674: 2668: 2667: 2639: 2633: 2632: 2630: 2629: 2606: 2600: 2599: 2589: 2579: 2570:(9): 1110–1114. 2555: 2549: 2548: 2538: 2523:Health Economics 2514: 2508: 2507: 2471: 2465: 2452: 2446: 2445: 2417: 2408: 2407: 2367: 2361: 2360: 2324: 2318: 2317: 2291: 2271: 2265: 2264: 2228: 2219: 2218: 2216: 2184: 2178: 2177: 2167: 2135: 2129: 2128: 2118: 2086: 2080: 2079: 2043: 2037: 2036: 2008: 2002: 2001: 1991: 1967: 1961: 1960: 1924: 1918: 1917: 1905: 1899: 1898: 1862: 1851: 1850: 1821: 1815: 1814: 1786: 1780: 1779: 1769: 1759: 1735: 1726: 1725: 1699: 1678: 1669: 1668: 1666: 1664: 1649: 1643: 1642: 1640: 1638: 1623: 1617: 1616: 1587: 1581: 1580: 1544: 1538: 1537: 1501: 1495: 1494: 1476: 1452: 1446: 1445: 1417: 1411: 1410: 1400: 1368: 1362: 1361: 1359: 1358: 1328: 1322: 1321: 1319: 1318: 1303: 1297: 1296: 1294: 1293: 1279: 1273: 1272: 1262: 1252: 1228: 1222: 1221: 1219: 1217: 1206: 1200: 1199: 1181: 1170:10.7326/M18-2390 1152: 1146: 1145: 1135: 1103: 1097: 1096: 1073:Gastroenterology 1067: 1061: 1060: 1050: 1035:Gastroenterology 1026: 1020: 1019: 982: 976: 975: 939: 933: 932: 914: 890: 875: 874: 872: 857: 848: 801: 797: 786: 774: 770: 766: 743: 736: 732: 729: 723: 692: 684: 675:Test performance 567:in blood, or at 542: 534: 531:Ingestion of 800 495:Marathon runners 477:Double-contrast 359:is discouraged. 160:Gastroenterology 141: 129: 128: 119: 118: 110: 107: 101: 99: 58: 27: 26: 19: 5025: 5024: 5020: 5019: 5018: 5016: 5015: 5014: 4985: 4984: 4983: 4978: 4969:Ranson criteria 4935: 4899: 4871: 4815: 4777: 4746:Cholangiography 4742:Medical imaging 4725:Cholecystostomy 4720:Cholecystectomy 4702: 4623: 4595: 4507:Medical imaging 4501: 4463: 4435: 4397: 4393:Strictureplasty 4368:Bowel resection 4356:Duodenal switch 4324: 4295:Medical imaging 4289: 4154: 4085:Digestive tract 4079: 4070: 4064: 4034: 4029: 3990:Lockwood's sign 3938: 3911: 3882:Ballance's sign 3853: 3820: 3814:Fluid wave test 3777: 3771:Blumberg's sign 3727: 3703:Rectal tenesmus 3670: 3610:Councilman body 3592: 3535:Goodsall's rule 3523:Hypersalivation 3440: 3433: 3420: 3390: 3385: 3384: 3361: 3360: 3304: 3227: 3222: 3221: 3184: 3180: 3145: 3141: 3122: 3118: 3081: 3077: 3064: 3063: 3059: 3044:10.4065/77.1.23 3028: 3024: 3015: 3013: 3009: 3008: 3004: 2964: 2960: 2923: 2919: 2910: 2908: 2904: 2903: 2899: 2894: 2890: 2859: 2855: 2824: 2820: 2789: 2785: 2762: 2758: 2721: 2717: 2708: 2706: 2701: 2700: 2696: 2687: 2685: 2676: 2675: 2671: 2640: 2636: 2627: 2625: 2607: 2603: 2556: 2552: 2536:10.1002/hec.819 2515: 2511: 2472: 2468: 2463:Wayback Machine 2453: 2449: 2418: 2411: 2368: 2364: 2325: 2321: 2289:10.1.1.556.6186 2276:Sports Medicine 2272: 2268: 2233:Sports Medicine 2229: 2222: 2185: 2181: 2136: 2132: 2087: 2083: 2044: 2040: 2009: 2005: 1968: 1964: 1925: 1921: 1906: 1902: 1863: 1854: 1822: 1818: 1787: 1783: 1736: 1729: 1679: 1672: 1662: 1660: 1651: 1650: 1646: 1636: 1634: 1625: 1624: 1620: 1588: 1584: 1545: 1541: 1502: 1498: 1453: 1449: 1418: 1414: 1369: 1365: 1356: 1354: 1330: 1329: 1325: 1316: 1314: 1305: 1304: 1300: 1291: 1289: 1281: 1280: 1276: 1229: 1225: 1215: 1213: 1208: 1207: 1203: 1153: 1149: 1104: 1100: 1068: 1064: 1027: 1023: 983: 979: 940: 936: 891: 878: 870: 855: 849: 845: 840: 828: 799: 795: 784: 781: 772: 768: 764: 761: 744: 733: 727: 724: 709: 693: 682: 677: 549: 540: 532: 497: 488: 373: 362:The use of the 287: 231: 164:general surgery 127: 120: 116: 111: 105: 102: 59: 48: 44:primary sources 28: 24: 17: 12: 11: 5: 5023: 5013: 5012: 5007: 5002: 4997: 4980: 4979: 4977: 4976: 4974:Milan criteria 4971: 4966: 4961: 4956: 4951: 4945: 4943: 4937: 4936: 4934: 4933: 4924: 4923: 4922: 4911: 4909: 4905: 4904: 4901: 4900: 4898: 4897: 4892: 4887: 4881: 4879: 4873: 4872: 4870: 4869: 4864: 4859: 4854: 4849: 4844: 4838: 4836: 4827: 4825:Abdominopelvic 4821: 4820: 4817: 4816: 4814: 4813: 4808: 4803: 4801:Pancreatectomy 4798: 4793: 4787: 4785: 4779: 4778: 4776: 4775: 4770: 4765: 4764: 4763: 4758: 4753: 4738: 4737: 4732: 4727: 4722: 4716: 4714: 4704: 4703: 4701: 4700: 4699: 4698: 4693: 4683: 4678: 4673: 4668: 4667: 4666: 4664:Liver dialysis 4661: 4650: 4648: 4639: 4633: 4632: 4629: 4628: 4625: 4624: 4622: 4621: 4616: 4611: 4609:Fecal fat test 4605: 4603: 4597: 4596: 4594: 4593: 4588: 4583: 4578: 4573: 4568: 4563: 4558: 4553: 4547: 4546: 4541: 4536: 4531: 4526: 4521: 4511: 4509: 4503: 4502: 4500: 4499: 4494: 4489: 4484: 4479: 4473: 4471: 4465: 4464: 4462: 4461: 4456: 4451: 4445: 4443: 4437: 4436: 4434: 4433: 4428: 4423: 4418: 4413: 4407: 4405: 4399: 4398: 4396: 4395: 4390: 4385: 4380: 4375: 4370: 4365: 4364: 4363: 4358: 4347: 4345: 4336: 4334:Lower GI tract 4330: 4329: 4326: 4325: 4323: 4322: 4317: 4315:Barium swallow 4312: 4311: 4310: 4299: 4297: 4291: 4290: 4288: 4287: 4285:Schilling test 4282: 4277: 4272: 4267: 4262: 4261: 4260: 4250: 4245: 4240: 4239: 4238: 4233: 4228: 4218: 4213: 4212: 4211: 4206: 4201: 4196: 4191: 4181: 4179:Gastric lavage 4176: 4171: 4164: 4162: 4156: 4155: 4153: 4152: 4147: 4142: 4137: 4132: 4127: 4122: 4120:Heller myotomy 4117: 4111: 4109: 4096: 4094:Upper GI tract 4087: 4081: 4080: 4075: 4072: 4071: 4063: 4062: 4055: 4048: 4040: 4031: 4030: 4028: 4027: 4025:Blumer's shelf 4022: 4017: 4015:Massouh's sign 4012: 4010:Carnett's sign 4007: 4002: 3997: 3992: 3987: 3982: 3977: 3972: 3967: 3965:Hamburger sign 3962: 3960:Rovsing's sign 3957: 3955:Obturator sign 3952: 3946: 3944: 3940: 3939: 3937: 3936: 3931: 3925: 3923: 3917: 3916: 3913: 3912: 3910: 3909: 3904: 3899: 3894: 3892:Castell's sign 3889: 3884: 3879: 3874: 3873: 3872: 3861: 3859: 3855: 3854: 3852: 3851: 3850: 3849: 3844: 3834: 3832:Abdominal mass 3828: 3826: 3822: 3821: 3819: 3818: 3817: 3816: 3811: 3806: 3801: 3796: 3785: 3783: 3779: 3778: 3776: 3775: 3774: 3773: 3768: 3763: 3758: 3753: 3746:Abdominal pain 3742: 3740: 3733: 3729: 3728: 3726: 3725: 3720: 3715: 3710: 3705: 3700: 3695: 3686: 3680: 3678: 3672: 3671: 3669: 3668: 3663: 3657: 3652: 3641: 3632: 3627: 3618: 3617: 3612: 3600: 3598: 3594: 3593: 3591: 3590: 3585: 3583:Hampton's line 3573: 3572: 3567: 3562: 3557: 3552: 3547: 3542: 3537: 3531: 3530: 3525: 3520: 3515: 3510: 3505: 3504: 3503: 3498: 3488: 3487: 3486: 3481: 3476: 3466: 3461: 3456: 3451: 3445: 3443: 3435: 3434: 3419: 3418: 3411: 3404: 3396: 3387: 3386: 3383: 3382: 3370: 3369: 3367: 3363: 3362: 3359: 3358: 3347: 3336: 3321: 3305: 3300: 3299: 3297: 3296:Classification 3290: 3289: 3263:(5): 466–470. 3252: 3246: 3237: 3226: 3225:External links 3223: 3220: 3219: 3198:(2): 135–141. 3178: 3139: 3116: 3075: 3057: 3022: 3002: 2975:(5): 866–872. 2958: 2937:(4): 746–750. 2917: 2897: 2888: 2869:(2): 121–126. 2853: 2834:(2): 245–252. 2818: 2783: 2772:(3): 131–135. 2756: 2715: 2694: 2669: 2634: 2601: 2550: 2529:(3): 227–238. 2509: 2482:(3): 140–141. 2466: 2447: 2428:(8): 565–576. 2424:(in Spanish). 2409: 2382:(8): 956–960. 2362: 2319: 2282:(5): 323–337. 2266: 2239:(4): 242–257. 2220: 2179: 2130: 2101:(3): 435–439. 2081: 2054:(5): 533–538. 2038: 2019:(4): 493–497. 2003: 1982:(7): 567–569. 1962: 1919: 1900: 1852: 1816: 1797:(4): 699–718. 1781: 1727: 1697:10.1.1.580.829 1670: 1644: 1633:. 19 June 2018 1618: 1599:(5): 468–473. 1582: 1539: 1496: 1447: 1428:(4): 417–425. 1412: 1383:(3): 277–285. 1363: 1338:. 2021-09-13. 1323: 1298: 1274: 1223: 1201: 1164:(5): 319–329. 1147: 1098: 1062: 1021: 977: 934: 905:(3): 739–750. 876: 842: 841: 839: 836: 827: 824: 816:false positive 780: 777: 760: 757: 746: 745: 696: 694: 687: 681: 678: 676: 673: 661: 660: 654: 600: 599: 548: 545: 518:immunoglobulin 496: 493: 487: 484: 483: 482: 475: 468: 463: 457: 447: 446: 441: 438:Angiodysplasia 435: 430: 425: 420: 414: 411:gastric cancer 372: 369: 286: 283: 267:gastric cancer 230: 227: 188:blood in stool 167: 166: 157: 151: 150: 143: 142: 134: 133: 125: 122: 121: 114: 112: 31: 29: 22: 15: 9: 6: 4: 3: 2: 5022: 5011: 5008: 5006: 5003: 5001: 4998: 4996: 4993: 4992: 4990: 4975: 4972: 4970: 4967: 4965: 4962: 4960: 4957: 4955: 4952: 4950: 4947: 4946: 4944: 4942: 4938: 4932: 4928: 4925: 4921: 4918: 4917: 4916: 4913: 4912: 4910: 4906: 4896: 4893: 4891: 4888: 4886: 4885:Hernia repair 4883: 4882: 4880: 4878: 4874: 4868: 4865: 4863: 4860: 4858: 4855: 4853: 4850: 4848: 4845: 4843: 4840: 4839: 4837: 4835: 4831: 4828: 4826: 4822: 4812: 4809: 4807: 4804: 4802: 4799: 4797: 4794: 4792: 4789: 4788: 4786: 4784: 4780: 4774: 4771: 4769: 4766: 4762: 4759: 4757: 4754: 4752: 4749: 4748: 4747: 4743: 4740: 4739: 4736: 4733: 4731: 4728: 4726: 4723: 4721: 4718: 4717: 4715: 4713: 4709: 4705: 4697: 4694: 4692: 4689: 4688: 4687: 4684: 4682: 4679: 4677: 4674: 4672: 4669: 4665: 4662: 4660: 4657: 4656: 4655: 4652: 4651: 4649: 4647: 4643: 4640: 4638: 4634: 4620: 4617: 4615: 4614:Fecal pH test 4612: 4610: 4607: 4606: 4604: 4602: 4598: 4592: 4589: 4587: 4584: 4582: 4579: 4577: 4574: 4572: 4569: 4567: 4564: 4562: 4559: 4557: 4554: 4552: 4549: 4548: 4545: 4544:Sigmoidoscopy 4542: 4540: 4537: 4535: 4532: 4530: 4527: 4525: 4522: 4520: 4516: 4513: 4512: 4510: 4508: 4504: 4498: 4495: 4493: 4490: 4488: 4485: 4483: 4480: 4478: 4475: 4474: 4472: 4470: 4466: 4460: 4457: 4455: 4452: 4450: 4447: 4446: 4444: 4442: 4438: 4432: 4429: 4427: 4424: 4422: 4419: 4417: 4414: 4412: 4409: 4408: 4406: 4404: 4400: 4394: 4391: 4389: 4386: 4384: 4381: 4379: 4376: 4374: 4371: 4369: 4366: 4362: 4359: 4357: 4354: 4353: 4352: 4349: 4348: 4346: 4344: 4340: 4337: 4335: 4331: 4321: 4318: 4316: 4313: 4309: 4306: 4305: 4304: 4301: 4300: 4298: 4296: 4292: 4286: 4283: 4281: 4280:Pyloromyotomy 4278: 4276: 4273: 4271: 4268: 4266: 4263: 4259: 4256: 4255: 4254: 4251: 4249: 4246: 4244: 4241: 4237: 4234: 4232: 4229: 4227: 4224: 4223: 4222: 4219: 4217: 4214: 4210: 4207: 4205: 4202: 4200: 4197: 4195: 4192: 4190: 4187: 4186: 4185: 4182: 4180: 4177: 4175: 4172: 4169: 4166: 4165: 4163: 4161: 4157: 4151: 4148: 4146: 4143: 4141: 4138: 4136: 4133: 4131: 4128: 4126: 4123: 4121: 4118: 4116: 4115:Esophagectomy 4113: 4112: 4110: 4108: 4104: 4100: 4097: 4095: 4091: 4088: 4086: 4082: 4078: 4073: 4069: 4061: 4056: 4054: 4049: 4047: 4042: 4041: 4038: 4026: 4023: 4021: 4018: 4016: 4013: 4011: 4008: 4006: 4003: 4001: 3998: 3996: 3993: 3991: 3988: 3986: 3983: 3981: 3980:Dunphy's sign 3978: 3976: 3973: 3971: 3970:Heel tap sign 3968: 3966: 3963: 3961: 3958: 3956: 3953: 3951: 3948: 3947: 3945: 3941: 3935: 3932: 3930: 3927: 3926: 3924: 3922: 3918: 3908: 3905: 3903: 3902:Cullen's sign 3900: 3898: 3895: 3893: 3890: 3888: 3885: 3883: 3880: 3878: 3875: 3871: 3868: 3867: 3866: 3863: 3862: 3860: 3856: 3848: 3845: 3843: 3840: 3839: 3838: 3835: 3833: 3830: 3829: 3827: 3823: 3815: 3812: 3810: 3807: 3805: 3802: 3800: 3797: 3795: 3792: 3791: 3790: 3787: 3786: 3784: 3780: 3772: 3769: 3767: 3764: 3762: 3759: 3757: 3754: 3752: 3751:Acute abdomen 3749: 3748: 3747: 3744: 3743: 3741: 3737: 3734: 3730: 3724: 3721: 3719: 3716: 3714: 3711: 3709: 3706: 3704: 3701: 3699: 3696: 3694: 3690: 3687: 3685: 3682: 3681: 3679: 3677: 3673: 3667: 3664: 3661: 3658: 3656: 3655:Lépine's sign 3653: 3651: 3650:Murphy's sign 3647: 3646: 3645:cholecystitis 3642: 3640: 3636: 3633: 3631: 3628: 3626: 3623: 3620: 3619: 3616: 3613: 3611: 3608: 3606: 3602: 3601: 3599: 3595: 3589: 3586: 3584: 3581: 3579: 3575: 3574: 3571: 3568: 3566: 3563: 3561: 3560:Markle's sign 3558: 3556: 3555:Arapov's sign 3553: 3551: 3548: 3546: 3543: 3541: 3538: 3536: 3533: 3532: 3529: 3526: 3524: 3521: 3519: 3516: 3514: 3511: 3509: 3506: 3502: 3499: 3497: 3496:oropharyngeal 3494: 3493: 3492: 3489: 3485: 3482: 3480: 3477: 3475: 3472: 3471: 3470: 3467: 3465: 3462: 3460: 3457: 3455: 3452: 3450: 3447: 3446: 3444: 3442: 3436: 3432: 3428: 3424: 3417: 3412: 3410: 3405: 3403: 3398: 3397: 3394: 3381: 3377: 3376: 3372: 3371: 3368: 3364: 3357: 3353: 3352: 3348: 3346: 3342: 3341: 3337: 3335: 3331: 3330: 3326: 3322: 3320: 3316: 3315: 3311: 3307: 3306: 3303: 3298: 3294: 3286: 3282: 3278: 3274: 3270: 3266: 3262: 3258: 3253: 3250: 3247: 3245: 3241: 3238: 3236: 3232: 3231:FOBT Overview 3229: 3228: 3215: 3211: 3206: 3201: 3197: 3193: 3189: 3182: 3174: 3170: 3166: 3162: 3158: 3154: 3150: 3143: 3135: 3131: 3127: 3120: 3112: 3108: 3103: 3098: 3094: 3090: 3086: 3079: 3071: 3067: 3061: 3053: 3049: 3045: 3041: 3037: 3033: 3026: 3012: 3006: 2998: 2994: 2990: 2986: 2982: 2978: 2974: 2970: 2962: 2954: 2950: 2945: 2940: 2936: 2932: 2928: 2921: 2907: 2901: 2892: 2884: 2880: 2876: 2872: 2868: 2864: 2857: 2849: 2845: 2841: 2837: 2833: 2829: 2822: 2814: 2810: 2806: 2802: 2798: 2794: 2787: 2779: 2775: 2771: 2767: 2760: 2752: 2748: 2743: 2738: 2734: 2730: 2726: 2719: 2704: 2698: 2684:on 2007-07-07 2683: 2679: 2673: 2665: 2661: 2657: 2653: 2649: 2645: 2638: 2624: 2620: 2616: 2612: 2605: 2597: 2593: 2588: 2583: 2578: 2573: 2569: 2565: 2561: 2554: 2546: 2542: 2537: 2532: 2528: 2524: 2520: 2513: 2505: 2501: 2497: 2493: 2489: 2485: 2481: 2477: 2470: 2464: 2460: 2457: 2451: 2443: 2439: 2435: 2431: 2427: 2423: 2416: 2414: 2405: 2401: 2397: 2393: 2389: 2385: 2381: 2377: 2373: 2366: 2358: 2354: 2350: 2346: 2342: 2338: 2334: 2330: 2323: 2315: 2311: 2307: 2303: 2299: 2295: 2290: 2285: 2281: 2277: 2270: 2262: 2258: 2254: 2250: 2246: 2242: 2238: 2234: 2227: 2225: 2215: 2210: 2206: 2202: 2198: 2194: 2190: 2183: 2175: 2171: 2166: 2161: 2157: 2153: 2150:(1): 100014. 2149: 2145: 2141: 2134: 2126: 2122: 2117: 2112: 2108: 2104: 2100: 2096: 2092: 2085: 2077: 2073: 2069: 2065: 2061: 2057: 2053: 2049: 2042: 2034: 2030: 2026: 2022: 2018: 2014: 2007: 1999: 1995: 1990: 1985: 1981: 1977: 1973: 1966: 1958: 1954: 1950: 1946: 1942: 1938: 1934: 1930: 1923: 1915: 1911: 1904: 1896: 1892: 1888: 1884: 1880: 1876: 1872: 1868: 1861: 1859: 1857: 1848: 1844: 1840: 1836: 1832: 1828: 1820: 1812: 1808: 1804: 1800: 1796: 1792: 1785: 1777: 1773: 1768: 1763: 1758: 1753: 1749: 1745: 1741: 1734: 1732: 1723: 1719: 1715: 1711: 1707: 1703: 1698: 1693: 1689: 1685: 1677: 1675: 1658: 1654: 1648: 1632: 1628: 1622: 1614: 1610: 1606: 1602: 1598: 1594: 1586: 1578: 1574: 1570: 1566: 1562: 1558: 1554: 1550: 1543: 1535: 1531: 1527: 1523: 1519: 1515: 1511: 1507: 1500: 1492: 1488: 1484: 1480: 1475: 1470: 1466: 1462: 1458: 1451: 1443: 1439: 1435: 1431: 1427: 1423: 1416: 1408: 1404: 1399: 1394: 1390: 1386: 1382: 1378: 1374: 1367: 1353: 1349: 1345: 1341: 1337: 1336:NIHR Evidence 1333: 1327: 1312: 1308: 1302: 1288: 1284: 1278: 1270: 1266: 1261: 1256: 1251: 1246: 1242: 1238: 1234: 1227: 1211: 1205: 1197: 1193: 1189: 1185: 1180: 1175: 1171: 1167: 1163: 1159: 1151: 1143: 1139: 1134: 1129: 1125: 1121: 1117: 1113: 1109: 1102: 1094: 1090: 1086: 1082: 1078: 1074: 1066: 1058: 1054: 1049: 1044: 1040: 1036: 1032: 1025: 1017: 1013: 1009: 1005: 1001: 997: 993: 989: 981: 973: 969: 965: 961: 957: 953: 949: 945: 938: 930: 926: 922: 918: 913: 908: 904: 900: 896: 889: 887: 885: 883: 881: 869: 866:(2): 153–58. 865: 861: 854: 847: 843: 835: 833: 823: 820: 817: 813: 808: 806: 793: 789: 776: 756: 753: 742: 739: 731: 721: 717: 713: 707: 706: 702: 697:This section 695: 691: 686: 685: 672: 670: 666: 658: 655: 651: 647: 643: 639: 636:component in 635: 631: 627: 623: 619: 615: 614: 610: 609: 604: 597: 593: 589: 585: 581: 577: 574: 573: 572: 570: 566: 562: 558: 554: 544: 538: 529: 527: 523: 519: 515: 511: 507: 503: 492: 480: 476: 473: 469: 467: 464: 461: 458: 455: 454:Sigmoidoscopy 452: 451: 450: 445: 442: 439: 436: 434: 431: 429: 426: 424: 421: 419: 415: 412: 408: 404: 400: 399: 398: 396: 392: 387: 385: 381: 377: 368: 365: 360: 358: 354: 348: 346: 337: 333: 331: 325: 323: 318: 316: 311: 308: 304: 301:In 2009, the 299: 296: 292: 282: 280: 276: 272: 268: 264: 260: 256: 255:peptic ulcers 252: 248: 244: 240: 236: 226: 224: 220: 216: 212: 208: 204: 199: 197: 193: 189: 185: 181: 177: 173: 165: 161: 158: 156: 152: 149: 144: 140: 135: 130: 113: 109: 106:November 2021 98: 95: 91: 88: 84: 81: 77: 74: 70: 67: –  66: 62: 61:Find sources: 56: 52: 46: 45: 41: 37: 32:This article 30: 21: 20: 4862:Paracentesis 4676:Liver biopsy 4571:Enteroclysis 4556:Defecography 4411:Appendectomy 3985:Alder's sign 3847:Splenomegaly 3842:Hepatomegaly 3708:Constipation 3697: 3643: 3621: 3615:Mallory body 3603: 3588:Klemm's sign 3576: 3550:Aaron's sign 3545:Dance's sign 3474:Trichophagia 3373: 3349: 3338: 3323: 3308: 3260: 3256: 3195: 3191: 3181: 3156: 3152: 3142: 3125: 3119: 3092: 3088: 3078: 3069: 3060: 3038:(1): 23–28. 3035: 3031: 3025: 3014:. Retrieved 3005: 2972: 2968: 2961: 2934: 2930: 2920: 2909:. Retrieved 2900: 2891: 2866: 2862: 2856: 2831: 2827: 2821: 2796: 2792: 2786: 2769: 2765: 2759: 2732: 2728: 2718: 2707:. Retrieved 2697: 2686:. Retrieved 2682:the original 2672: 2650:(1): 38–46. 2647: 2643: 2637: 2626:. Retrieved 2614: 2604: 2567: 2563: 2553: 2526: 2522: 2512: 2479: 2475: 2469: 2450: 2425: 2421: 2379: 2375: 2365: 2332: 2328: 2322: 2279: 2275: 2269: 2236: 2232: 2199:(6410): 65. 2196: 2192: 2182: 2147: 2143: 2133: 2098: 2094: 2084: 2051: 2047: 2041: 2016: 2012: 2006: 1979: 1975: 1965: 1932: 1928: 1922: 1913: 1909: 1903: 1873:(2): 89–94. 1870: 1866: 1830: 1826: 1819: 1794: 1790: 1784: 1747: 1743: 1690:(2): 81–85. 1687: 1683: 1661:. Retrieved 1656: 1647: 1635:. Retrieved 1630: 1621: 1596: 1592: 1585: 1552: 1548: 1542: 1509: 1505: 1499: 1464: 1460: 1450: 1425: 1421: 1415: 1380: 1376: 1366: 1355:. Retrieved 1335: 1326: 1315:. Retrieved 1313:. 2017-10-20 1310: 1301: 1290:. Retrieved 1286: 1277: 1240: 1236: 1226: 1214:. Retrieved 1204: 1161: 1157: 1150: 1115: 1111: 1101: 1076: 1072: 1065: 1038: 1034: 1024: 994:(1): 54–60. 991: 987: 980: 950:(2): 75–82. 947: 943: 937: 902: 898: 863: 859: 846: 829: 821: 809: 790: 782: 762: 749: 734: 725: 710:Please help 698: 662: 617: 611: 587: 583: 579: 575: 550: 530: 498: 489: 479:barium enema 448: 440:of the colon 388: 374: 361: 349: 342: 330:colon cancer 326: 320:The English 319: 312: 300: 288: 271:colon cancer 232: 229:Medical uses 200: 196:hematochezia 178:) refers to 175: 171: 170: 103: 93: 86: 79: 72: 60: 40:verification 33: 5010:Stool tests 4995:Blood tests 4852:Laparoscopy 4708:Gallbladder 4671:Hepatectomy 4601:Stool tests 4539:Proctoscopy 4534:Enteroscopy 4519:Colonoscopy 4403:Large bowel 4383:Jejunostomy 4343:Small bowel 4270:Hill repair 4253:Gastrostomy 4231:Billroth II 4221:Gastrectomy 4125:Sialography 4000:Cupola sign 3897:Kehr's sign 3877:Puddle sign 3508:Odynophagia 3375:MedlinePlus 3235:Mayo Clinic 1663:11 December 1637:11 December 1243:: 177–187. 665:transferrin 547:Methodology 520:levels and 502:hematemesis 460:Colonoscopy 428:Hemorrhoids 307:colonoscopy 215:transferrin 34:needs more 4989:Categories 4915:Laparotomy 4857:Omentopexy 4834:Peritoneum 4469:Anal canal 4248:Gastropexy 4226:Billroth I 3950:Psoas sign 3782:Distension 3761:Baby colic 3693:encopresis 3684:Flatulence 3676:Defecation 3666:Nardi test 3625:Boas' sign 3518:Xerostomia 3513:Bad breath 3501:esophageal 3479:Pagophagia 3464:Aerophagia 3351:DiseasesDB 3016:2007-10-25 2911:2007-07-18 2709:2007-07-18 2688:2007-07-18 2628:2021-01-12 1357:2022-08-05 1317:2022-08-05 1292:2022-08-05 1179:1805/21570 838:References 826:Regulation 642:peroxidase 638:hemoglobin 594:to detect 592:antibodies 565:porphyrins 553:antibodies 537:cimetidine 526:hypertonic 514:leucocytes 364:M2-PK Test 259:malignancy 76:newspapers 4712:bile duct 4637:Accessory 4515:Endoscopy 4426:Colostomy 4416:Colectomy 4373:Ileostomy 4303:Endoscopy 4236:Roux-en-Y 4107:Esophagus 3597:Accessory 3491:Dysphagia 3484:Geophagia 3459:Heartburn 2623:0362-4331 2284:CiteSeerX 1929:Endoscopy 1692:CiteSeerX 1352:239113610 1016:218910557 812:porphyrin 807:article. 728:June 2019 699:does not 620:): – The 516:, and in 472:endoscopy 295:Screening 275:screening 261:(such as 221:look for 155:Specialty 4783:Pancreas 4524:Anoscopy 3865:Jaundice 3794:Bloating 3718:Diarrhea 3622:biliary: 3454:Vomiting 3285:41529458 3277:20664346 3240:Overview 3214:20060198 3173:17961818 3134:20722162 3052:11794453 2997:46949140 2989:29871970 2953:19408302 2778:20701065 2751:19661074 2664:10387941 2596:20205282 2545:14981648 2504:26481612 2496:19174764 2459:Archived 2442:19577340 2314:25330480 2306:11929359 2261:26732943 2174:35600744 2125:11171839 2076:21085826 2068:19535976 1998:28699947 1957:34757654 1895:40548811 1887:24644029 1847:18054752 1811:16303578 1776:22912551 1722:29833684 1714:15657155 1577:37515050 1534:11395104 1442:20833346 1407:33342370 1269:29270036 1196:67876943 1188:30802902 1142:32128688 1093:28600072 1057:27769517 1008:10672835 972:29966595 964:11060470 921:19240699 868:Archived 669:cytology 510:secretin 291:adenomas 190:such as 4160:Stomach 3804:Tympany 3799:Ascites 3732:Abdomen 3528:Burping 3431:abdomen 3345:D009780 3111:6640900 2848:7313535 2813:3873009 2705:. WebMD 2587:2835788 2404:1978110 2396:2384041 2357:8264981 2349:1914760 2253:8460288 2214:1444190 2165:9115725 2116:1760153 2033:3487825 1949:2428607 1767:3419997 1613:8036464 1569:8942774 1526:8942775 1491:6756273 1483:8474513 1398:8366184 1260:5720037 1216:7 April 1133:7280423 720:removed 705:sources 582:), and 401:2–10%: 382:before 241:to the 182:in the 90:scholar 55:removed 4877:Hernia 4441:Rectum 3921:Hernia 3825:Masses 3449:Nausea 3380:007008 3283:  3275:  3212:  3171:  3132:  3109:  3050:  2995:  2987:  2951:  2883:307949 2881:  2846:  2811:  2776:  2749:  2662:  2621:  2594:  2584:  2543:  2502:  2494:  2440:  2402:  2394:  2355:  2347:  2312:  2304:  2286:  2259:  2251:  2211:  2172:  2162:  2123:  2113:  2074:  2066:  2031:  1996:  1955:  1947:  1893:  1885:  1845:  1809:  1774:  1764:  1720:  1712:  1694:  1659:. 2018 1611:  1575:  1567:  1549:Lancet 1532:  1524:  1506:Lancet 1489:  1481:  1440:  1405:  1395:  1350:  1311:nhs.uk 1267:  1257:  1194:  1186:  1140:  1130:  1091:  1055:  1014:  1006:  970:  962:  929:295873 927:  919:  810:Fecal 800:  796:  785:  773:  769:  765:  640:has a 596:globin 561:globin 541:  535:mg of 533:  418:polyps 403:cancer 345:anemia 279:anemia 207:globin 192:melena 92:  85:  78:  71:  63:  5005:Feces 4959:UKELD 4908:Other 4646:Liver 3943:Other 3858:Other 3756:Colic 3605:liver 3441:tract 3356:30751 3334:792.1 3319:R19.5 3281:S2CID 2993:S2CID 2500:S2CID 2400:S2CID 2353:S2CID 2310:S2CID 2257:S2CID 2072:S2CID 1953:S2CID 1916:: 34. 1891:S2CID 1718:S2CID 1573:S2CID 1530:S2CID 1487:S2CID 1348:S2CID 1192:S2CID 1012:S2CID 968:S2CID 925:S2CID 871:(PDF) 860:JIACM 856:(PDF) 630:blood 618:gFOBT 588:iFOBT 563:, or 257:or a 243:colon 239:mouth 184:feces 180:blood 97:JSTOR 83:books 4954:PELD 4949:MELD 4756:MRCP 4730:ERCP 3739:Pain 3691:and 3469:Pica 3340:MeSH 3329:9-CM 3273:PMID 3210:PMID 3169:PMID 3130:PMID 3107:PMID 3048:PMID 2985:PMID 2949:PMID 2879:PMID 2844:PMID 2809:PMID 2774:PMID 2747:PMID 2660:PMID 2619:ISSN 2592:PMID 2541:PMID 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