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Shown also is the major classes of steroid hormones: progestagens, mineralocorticoids, glucocorticoids, androgens and estrogens. However, they partly overlap, e.g. mineralocorticoids and glucocorticoids. White circles indicate changes in molecular structure compared with precursors. For more
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490:Ферменты, участвующие в стероидогенезе человека, с указанием субстратов и продуктов, а также локализации их активности. Происходящие изменения в структуре молекул отмечены белыми кружочками. По сборнику "Медицинская физиология" (Walter F. Boron, Emile L. Boulpaep, 2003 год).
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by waiving all of their rights to the work worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law. You can copy, modify, distribute and perform the work, even for commercial purposes, all without asking permission.
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A short flashback of some milestones the evolution of the picture, demonstrating the power of free licensing where anybody can contribute to making things better.
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There is no appreciable conversion of corticosterone to cortisol in the adrenal cortex as 21-OH steroids are poor substrates for 17-alpha hydroxylase.
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Fixed reaction scheme: corticosterone doesn't go to cortisol! Karl and Lindie, why didn't you fix it when you first found out? Tsk tsk.
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Uwagi: W miejscu gdzie stereochemia nie jest wyświetlana, jest taka sama jak dla
Cholesterol lub w pokazanej powyżej grupie.
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Added stereochemistries, removed redundant white circle at cortisol, renamed 21-alpha hydroxylase to simply 21-hydroxylase.
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Payne AH, Hales DB (2004). "Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones".
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Corticosterone to Cortisol via CYP17A1 (see http://www.genome.jp/kegg-bin/show_pathway?ko00140+C02140 )
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Hanukoglu I (1992). "Steroidogenic enzymes: structure, function, and role in regulation of steroid hormone biosynthesis".
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5. (March 2009) Expansion, grouping, addition of enzyme localization, numbering of cholesterol and coloring by
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File uploaded using svgtranslate tool (https://tools.wmflabs.org/svgtranslate/). Added translation for uk.
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A schematic diagram showing the chemicals, enzymes, and locations of the human steroidogenesis pathways.
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A schematic diagram showing the chemicals, enzymes, and locations of the human steroidogenesis pathways.
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If you think this file should be featured on
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Häggström M, Richfield D (2014). "Diagram of the pathways of human steroidogenesis".
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WikiJournal of
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Addition and correction of stereochemistries at positions 11 and 17.
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Click on a date/time to view the file as it appeared at that time.
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Enzymes, their cellular location, substrates and products in human
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Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency
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Congenital adrenal hyperplasia due to 21-hydroxylase deficiency
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copyrighted, dedicated to the public domain by copyright holder
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copyrighted, dedicated to the public domain by copyright holder
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For the absence of conversion of corticosterone to cortisol:
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Wikiversity:Diagram of the pathways of human steroidogenesis
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Knowledge:Knowledge
Signpost/2009-04-13/Features and admins
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3. (November 2007) Organization and addition of enzymes by
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information on interpretation of molecular structures, see
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The
Journal of Steroid Biochemistry and Molecular Biology
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http://creativecommons.org/publicdomain/zero/1.0/deed.en
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Medical
Physiology: A Cellular And Molecular Approach
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Creative Commons Attribution-ShareAlike 3.0 Unported
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Creative Commons Attribution-ShareAlike 3.0 Unported
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Commons is a freely licensed media file repository.
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Align some text and arrows for neatness' sake.
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Steroid hormone biosynthesis Reference pathway (KO)
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478:Enzymy biorące udział w steroidogenezie.
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334:HSD: Hydroxysteroid dehydrogenase
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2344:Portal:Medicine
2204:Steroid hormone
2034:Androstenedione
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2582:Corticosterona
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2562:Androstendiona
2559:
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2074:Corticosterone
2071:
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2029:Androstenediol
2026:
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2016:
2011:
2006:
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1999:21-Hydroxylase
1996:
1991:
1986:
1981:
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1920:
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1903:1,245 × 1,105
1901:
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1873:1,245 × 1,105
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1811:
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1783:1,245 × 1,105
1781:
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1753:1,245 × 1,105
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1723:1,245 × 1,105
1721:
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1697:
1693:1,245 × 1,105
1691:
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1663:1,245 × 1,105
1661:
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1633:1,245 × 1,105
1631:
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401:(8): 779–804.
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2600:
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2577:Citocrom p450
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2520:
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2498:
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2487:Androstendiol
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2475:
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2472:Spolni hormon
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2069:Corpus luteum
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1641:Bjankuloski06
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1331:image/svg+xml
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1293:28 March 2009
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1061:
1042:
1041:public domain
1038:
1037:
1033:
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1012:
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964:
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945:
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936:
928:
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904:
900:
897:, be sure to
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849:
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845:
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828:
824:
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773:
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738:
733:
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673:
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512:28 March 2009
506:
501:
496:
488:
481:
476:
468:
465:
464:
463:
462:
454:
450:
443:
438:
434:(6): 947–70.
433:
430:
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359:1-4160-2328-3
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83:Original file
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38:
35:
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30:
28:
25:
23:
20:
18:
15:
2703:
2700:
2688:
2682:Testosterona
2557:Progesterona
2387:Testosterona
2358:
2229:Testosterone
2174:Progesterone
2164:Pregnenolone
2009:5α-Reductase
1968:
1552:
1549:File history
1045:
934:
886:
872:
855:
657:Translations
640:
639:
627:
592:
589:
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559:
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371:
345:
337:
336:
333:
325:
316:
270:Translations
220:
181:
180:
141:You can help
131:
81:
22:File history
2632:Οιστραδιόλη
2592:Testosteron
2482:Pregnenolon
2442:Žuto tijelo
2402:এস্ট্রাডিওল
2189:Sex hormone
2184:Progestogen
2044:Cholesterol
2019:Aldosterone
1671:Uxue García
1151:copyrighted
1121:copyrighted
907:nominate it
889:nominate it
644:. See also
338:References:
308:Description
201:nominate it
99:Basque (eu)
2731:Categories
2452:Aldosteron
2397:কোলেস্টেরল
2234:Trilostane
1965:File usage
1609:Dimensions
1316:media type
1306:media type
183:identified
171:This is a
27:File usage
2547:Aromatasa
2437:Estradiol
2104:Estradiol
1606:Thumbnail
1603:Date/Time
1425:data size
1411:data size
1278:inception
1268:inception
1007:Licensing
968:Hoffmeier
944:Stannered
931:Evolution
827:path text
764:InfoField
646:Evolution
584:(2014). "
570:Hoffmeier
487:Русский:
461:See also:
317:English:
292:Licensing
282:Evolution
2697:Metadata
2552:Androgen
2532:Estrogen
2467:Androgen
2457:Kortizol
2114:Estrogen
2079:Cortisol
2024:Androgen
1935:older 10
1931:newer 10
1929:) View (
1905:(114 KB)
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1845:(114 KB)
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