229:, Oudit's research team examined circulating angiotensin peptide levels in the blood of over 100 individuals who were experiencing heart failure due to a heart attack or stroke. Following this, Oudit also led a collaborative study between U of A and teams from Cambridge, Boston, and Berlin to use analytical techniques to sequence the ribonucleic acids in nine types of single cells from six regions of the heart. His work was later recognized with an appointment to become a Fellow of the
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identified a key molecule named PI3K alpha that binds to gelsolin and suppresses it. As a result of this discovery, Oudit hypothesized that they could develop new treatments that could help counter the threat. Later that year, Oudit used mice studies to pinpoint a link between a peptide and a reduction of abdominal aortic aneurysms.
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in Heart
Failure in 2014. In this new role, Oudit's research team discovered ACE2, a molecule that works to naturally block the renin-angiotensin system and correct any imbalance. Based on this, they created a recombinant version of that protein to turn it into a drug. In 2019, Oudit's research team
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to fund his research on super enzymes. Based on his research, Oudit helped established the human explanted heart program (HELP) at the institution aimed at translating discoveries to help people live better and longer lives. As an
193:(U of T). Upon graduating, he remained at the institution to complete his training in internal medicine and adult cardiology. Oudit then accepted a four-year post-doctoral fellowship in the molecular biology of heart failure.
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in the
Faculty of Medicine & Dentistry, Oudit also oversaw a study that found a deficiency in the peptide apelin was associated with heart failure, pulmonary hypertension and diabetes.
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Role of L-type Ca²+ channel and oxidative stress in the pathogenesis of iron-overload cardiomyopathy: calcium channel blockers and taurine as potential therapies.
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205:(U of A) as a Mazankowski Heart Institute scientist. In this role, he received the 2010 McDonald Scholarship from the
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402:"U of A researchers developing new treatment that could help protect people with cardiovascular disease"
425:"New diagnostic test for heart failure patients could also help COVID-19 patients: U of A researchers"
165:, Oudit also serves as Director of the Heart Function Clinic and Mazankowski Alberta Heart Institute.
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448:"New 'atlas' of human heart cells first step toward precision treatments for heart disease"
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471:"Canadian Academy of Health Sciences welcomes five FoMD researchers as new Fellows"
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Due to his overall research success, Oudit was the recipient of a Tier 2
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356:"University of Alberta research fuels emergence of new heart drug"
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Oudit is married to
Zamaneh Kassiri, a fellow U of A professor.
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is a
Canadian cardiologist and clinician-scientist. As a Tier 2
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Upon completing his training, Oudit joined the faculty at the
379:"Researchers discover a hidden culprit in heart failure"
310:"Eleven Canada Research Chairs announced for UAlberta"
540:Fellows of the Canadian Academy of Health Sciences
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285:"U of A scientist pumped over heart scholarship"
16:Canadian cardiologist and clinician-scientist
525:Academic staff of the University of Alberta
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446:Rutherford, Gillian (September 24, 2020).
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333:"New Class of Drug Targets Heart Disease"
191:University of Toronto Faculty of Medicine
110:University of Toronto Faculty of Medicine
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259:"Profile of Gavin Oudit, MD, PhD, FRCPC"
312:. University of Alberta. March 31, 2014
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423:Rutherford, Gillian (July 20, 2020).
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261:. University of Alberta
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159:Canada Research Chair
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103:BSc, MSc, PhD, 2005,
173:Oudit completed his
212:associate professor
175:Bachelor of Science
95:Academic background
358:. Edmonton Journal
287:. Edmonton Journal
150:Gavin Yadram Oudit
57:for suggestions.
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227:COVID-19 pandemic
179:Master of Science
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134:Institutions
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225:During the
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40:link to it
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100:Education
43:. Please
185:and his
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154:FCAHS
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