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Gluconic acid

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Gluconate is also used in building and construction as a concrete admixture (retarder) to slow down the cement hydration reactions, and to delay the cement setting time. It allows for a longer time to lay the concrete, or to spread the cement hydration heat over a longer period of time to avoid too
890:; calcium gluconate injections may be used for more severe cases to avoid necrosis of deep tissues, as well as to treat hypocalcemia in hospitalized patients. Gluconate is also an electrolyte present in certain solutions, such as " 841:
high a temperature and the resulting cracking. Retarders are mixed in to concrete when the weather temperature is high or to cast large and thick concrete slabs in successive and sufficiently well-mixed layers.
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Gluconic acid was first prepared by Hlasiwetz and Habermann in 1870 and involved the chemical oxidation of glucose. In 1880, Boutroux prepared and isolated gluconic acid using the glucose fermentation.
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Ma, Suhua; Li, Weifeng; Zhang, Shenbiao; Ge, Dashun; Yu, Jin; Shen, Xiaodong (2015). "Influence of sodium gluconate on the performance and hydration of Portland cement".
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Roblin I.; Urban M.; Flicoteau D.; Martin C.; Pradeau D. (2006). "Topical treatment of experimental hydrofluoric acid skin burns by 2.5% calcium gluconate".
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Wong, Chun Ming; Wong, Kwun Hei; Chen, Xiao Dong (2008). "Glucose oxidase: Natural Occurrence, Function, Properties and Industrial Applications".
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Ramachandran, V.S.; Lowery, M.S. (1992). "Conduction calorimetric investigation of the effect of retarders on the hydration of Portland cement".
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Yan, Wenjuan; Zhang, Dongpei; Sun, Yu; Zhou, Ziqi; Du, Yihang; Du, Yiyao; Li, Yushan; Liu, Mengyuan; Zhang, Yuming; Shen, Jian; Jin, Xin (2020).
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Mycielska, ME; Mohr, MTJ; Schmidt, K; Drexler, K; Rümmele, P; Haferkamp, S; Schlitt, HJ; Gaumann, A; Adamski, J; Geissler, EK (2019).
1179:"Sustainable production of high-value gluconic acid and glucaric acid through oxidation of biomass-derived glucose: A critical review" 1522:
el Saadi M. S.; Hall A. H.; Hall P. K.; Riggs B. S.; Augenstein W. L.; Rumack B. H. (1989). "Hydrofluoric acid dermal exposure".
37: 956: 543: 46: 377: 1130:"Structural sensitivity of heterogeneous catalysts for sustainable chemical synthesis of gluconic acid from glucose" 555: 72: 1668: 1658: 1319:
Comparison of intratesticular injection of zinc gluconate versus surgical castration to sterilize male dogs
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Singh, Om V.; Kumar, Raj (2007). "Biotechnological production of gluconic acid: future implications".
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Gluconic acid is typically produced by the aerobic oxidation of glucose in the presence of the enzyme
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The preparation of ferrous gluconate and its use in the treatment of hypochromic anelia in rats.
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of gluconic acid are known as "gluconates". Gluconic acid, gluconate salts, and gluconate
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InChI=1S/C6H12O7/c7-1-2(8)3(9)4(10)5(11)6(12)13/h2-5,7-11H,1H2,(H,12,13)/t2-,3-,4+,5-/m1/s1
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InChI=1/C6H12O7/c7-1-2(8)3(9)4(10)5(11)6(12)13/h2-5,7-11H,1H2,(H,12,13)/t2-,3-,4+,5-/m1/s1
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Intra-Arterial Calcium Gluconate Treatment After Hydrofluoric Acid Burn of the Hand
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Variations of glucose (or other carbohydrate-containing substrate) oxidation using
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In medicine, gluconate is used most commonly as a biologically neutral carrier of
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Journal of Pharmacology and Experimental Therapy, volume 59 issue 2, page 182.
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Julie K. Levy, P. Cynda Crawford, Leslie D. Appel, Emma L. Clifford (2008),
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Zhang, Qiaozhi; Wan, Zhonghao; Yu, Iris K. M.; Tsang, Daniel C. W. (2021).
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D. Thomas, U. Jaeger, I. Sagoschen, C. Lamberti and K. Wilhelm (2009),
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gluconate is a salt of gluconic acid and quinine, which is used for
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Except where otherwise noted, data are given for materials in their
820: 674:. The lactone spontaneously hydrolyzes to gluconic acid in water. 639: 275: 166: 903: 895: 844:
Gluconic acid aqueous solution finds application as a medium for
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Chemical Engineering and Processing: Process Intensification
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of gluconic acid consists of a six-carbon chain, with five
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occur widely in nature because such species arise from the
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Pal, Parimal; Kumar, Ramesh; Banerjee, Subhamay (2016).
1331: 626:. Some drugs are injected in the form of gluconates. 276: 886:, in the form of a gel, is used to treat burns from 912:injections have been proposed in the past to treat 1337: 1241: 1305:Current EU approved additives and their E Numbers 1640: 1080: 303: 1176: 1127: 141: 129: 1473:"Potential Use of Gluconate in Cancer Therapy" 1248:Berichte der Deutschen Chemischen Gesellschaft 1611:Paul Reznikoff and Walther F. Goebel (1937), 1285:[On a new fermentation of glucose]. 894:", used for intravenous fluid resuscitation. 1542: 1415: 986: 642:groups positioned in the same way as in the 1515: 1380: 1416:Lim, Han Yin; Dolzhenko, Anton V. (2021). 1283:"Sur une fermentation nouvelle du glucose" 1029: 361: 248: 226: 1699:Substances discovered in the 19th century 1498: 1488: 1287:Comptes Rendus de l'Académie des Sciences 1210: 1145: 323: 1374: 1280: 654:of 2,3,4,5,6-pentahydroxyhexanoic acid. 357: 1641: 1032:Applied Microbiology and Biotechnology 989:Applied Microbiology and Biotechnology 766: 489:131 °C (268 °F; 404 K) 239: 1242:Hlasiwetz, H.; Habermann, J. (1870). 629: 389:Key: RGHNJXZEOKUKBD-SQOUGZDYSA-N 206: 186: 93:)-2,3,4,5,6-Pentahydroxyhexanoic acid 1383:Construction and Building Materials 399:Key: RGHNJXZEOKUKBD-SQOUGZDYBY 294: 13: 1563:10.1097/01.BCR.0000245767.54278.09 1422:Sustainable Chemistry and Pharmacy 771:Gluconic acid occurs naturally in 14: 1710: 1622: 1395:10.1016/j.conbuildmat.2015.05.068 977:, Chemical Society, London, 1958. 610:in neutral aqueous solution. The 1634:ChemSub Online: D-Gluconic acid. 606:H. A white solid, it forms the 533: 447: 45: 36: 1605: 1585: 1464: 1409: 1311: 1297: 529:(at 25 °C , 100 kPa). 1274: 1235: 1170: 1121: 1074: 1023: 980: 967: 949: 815:, and other metals, including 787:(E574), it is now known as an 453: 441: 1: 1203:10.1016/j.jclepro.2021.127745 1183:Journal of Cleaner Production 1147:10.1016/S1872-2067(20)63590-2 942: 657: 1360:10.1016/0040-6031(92)80081-7 1134:Chinese Journal of Catalysis 644:open-chained form of glucose 7: 919: 851: 666:. The conversion produces 650:group. It is one of the 16 10: 1715: 15: 1629:Gluconic acid on NIST.gov 1601:10.1007/s00270-008-9361-1 1442:10.1016/j.scp.2021.100443 1260:10.1002/cber.187000301162 1107:10.1016/j.cep.2016.03.009 1044:10.1007/s00253-007-0851-x 1001:10.1007/s00253-008-1407-4 961:American Chemical Society 523: 428: 408: 373: 284:(acidity regulators, ...) 113: 99: 71: 58: 53: 44: 35: 1308:. Food Standards Agency. 16:Not to be confused with 1490:10.3389/fonc.2019.00522 900:intramuscular injection 833:injections are used to 1477:Frontiers in Oncology 1327:10.2460/ajvr.69.1.140 1281:Boutroux, L. (1880). 878:electrolyte imbalance 823:. It is also used in 73:Systematic IUPAC name 973:Bjerrum, J., et al. 902:in the treatment of 794:The gluconate anion 420:O=C(O)(O)(O)(O)(O)CO 1669:Concrete admixtures 1659:Alpha hydroxy acids 1434:2021SusCP..2100443L 1352:1992TcAc..195..373R 1195:2021JCPro.31227745Z 1099:2016CEPPI.104..160P 975:Stability Constants 936:Isosaccharinic acid 767:Occurrence and uses 646:, terminating in a 496:Solubility in water 479:Colorless crystals 471: g·mol 32: 1674:E-number additives 1340:Thermochimica Acta 636:chemical structure 630:Chemical structure 592:structural formula 556:Infobox references 27: 1684:Radioactive waste 957:"D-Gluconic acid" 910:Ferrous gluconate 888:hydrofluoric acid 884:Calcium gluconate 846:organic synthesis 825:cleaning products 789:acidity regulator 672:hydrogen peroxide 576:molecular formula 564:Chemical compound 562: 561: 342:CompTox Dashboard 168:Interactive image 1706: 1664:Chelating agents 1616: 1609: 1603: 1589: 1583: 1582: 1546: 1540: 1539: 1519: 1513: 1512: 1502: 1492: 1468: 1462: 1461: 1413: 1407: 1406: 1378: 1372: 1371: 1335: 1329: 1315: 1309: 1301: 1295: 1294: 1278: 1272: 1271: 1239: 1233: 1232: 1214: 1174: 1168: 1167: 1149: 1140:(9): 1320–1336. 1125: 1119: 1118: 1078: 1072: 1071: 1027: 1021: 1020: 984: 978: 971: 965: 964: 953: 875: 871: 867: 863: 859: 809: 747: 715: 572:organic compound 546: 540: 537: 536: 470: 455: 449: 443: 436:Chemical formula 366: 365: 350: 348: 327: 307: 296: 278: 260: 252: 241: 230: 210: 190: 170: 146: (racemate) 145: 133: 65: 49: 40: 33: 30: 26: 1714: 1713: 1709: 1708: 1707: 1705: 1704: 1703: 1639: 1638: 1625: 1620: 1619: 1610: 1606: 1590: 1586: 1551:J Burn Care Res 1547: 1543: 1524:Vet Hum Toxicol 1520: 1516: 1469: 1465: 1414: 1410: 1379: 1375: 1336: 1332: 1316: 1312: 1302: 1298: 1279: 1275: 1240: 1236: 1175: 1171: 1126: 1122: 1079: 1075: 1028: 1024: 985: 981: 972: 968: 955: 954: 950: 945: 931:Glucuronic acid 922: 873: 869: 865: 861: 857: 854: 807: 769: 746: 742: 738: 734: 730: 726: 722: 718: 714: 710: 706: 702: 698: 694: 690: 686: 682: 678: 664:glucose oxidase 660: 648:carboxylic acid 632: 608:gluconate anion 605: 601: 597: 589: 585: 581: 565: 558: 553: 552: 551:  ?) 542: 538: 534: 530: 515: 498: 468: 458: 452: 446: 438: 424: 421: 416: 415: 404: 401: 400: 397: 391: 390: 387: 381: 380: 369: 351: 344: 335: 310: 297: 270: 233: 213: 193: 173: 160: 149: 123: 109: 108: 95: 94: 67: 63: 31:-Gluconic acid 28: 25: 22:Glutaconic acid 18:Glucuronic acid 12: 11: 5: 1712: 1702: 1701: 1696: 1691: 1686: 1681: 1679:Food additives 1676: 1671: 1666: 1661: 1656: 1651: 1637: 1636: 1631: 1624: 1623:External links 1621: 1618: 1617: 1604: 1584: 1541: 1514: 1463: 1408: 1373: 1330: 1310: 1296: 1273: 1254:(1): 486–495. 1234: 1169: 1120: 1073: 1038:(4): 713–722. 1022: 995:(6): 927–938. 979: 966: 947: 946: 944: 941: 940: 939: 933: 928: 921: 918: 853: 850: 831:Zinc gluconate 768: 765: 749: 748: 744: 740: 736: 732: 728: 724: 720: 716: 712: 708: 704: 700: 696: 692: 688: 684: 680: 668:gluconolactone 659: 656: 631: 628: 603: 599: 595: 590:and condensed 587: 583: 579: 563: 560: 559: 554: 532: 531: 527:standard state 524: 521: 520: 517: 513: 503: 502: 499: 494: 491: 490: 487: 481: 480: 477: 473: 472: 466: 460: 459: 456: 450: 444: 439: 434: 431: 430: 426: 425: 423: 422: 419: 411: 410: 409: 406: 405: 403: 402: 398: 395: 394: 392: 388: 385: 384: 376: 375: 374: 371: 370: 368: 367: 354: 352: 340: 337: 336: 334: 333: 320: 318: 312: 311: 309: 308: 300: 298: 290: 287: 286: 280: 272: 271: 269: 268: 264: 262: 254: 253: 243: 235: 234: 232: 231: 223: 221: 215: 214: 212: 211: 203: 201: 195: 194: 192: 191: 183: 181: 175: 174: 172: 171: 163: 161: 154: 151: 150: 148: 147: 139: 126: 124: 119: 116: 115: 111: 110: 107: 106: 105:Dextronic acid 102: 101: 97: 96: 76: 75: 69: 68: 66:-Gluconic acid 62: 56: 55: 51: 50: 42: 41: 9: 6: 4: 3: 2: 1711: 1700: 1697: 1695: 1694:Vicinal diols 1692: 1690: 1687: 1685: 1682: 1680: 1677: 1675: 1672: 1670: 1667: 1665: 1662: 1660: 1657: 1655: 1654:Acids in wine 1652: 1650: 1647: 1646: 1644: 1635: 1632: 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836: 832: 828: 826: 822: 818: 814: 810: 804: 800: 797: 792: 790: 786: 785:food additive 782: 778: 774: 764: 760: 758: 754: 717: 677: 676: 675: 673: 669: 665: 655: 653: 652:stereoisomers 649: 645: 641: 637: 627: 625: 621: 617: 613: 609: 593: 577: 573: 569: 568:Gluconic acid 557: 550: 545: 528: 522: 518: 512: 508: 505: 504: 500: 497: 493: 492: 488: 486: 485:Melting point 483: 482: 478: 475: 474: 467: 465: 462: 461: 440: 437: 433: 432: 427: 418: 417: 414: 407: 393: 383: 382: 379: 372: 364: 360: 359:DTXSID8027169 356: 355: 353: 343: 339: 338: 331: 326: 322: 321: 319: 317: 314: 313: 306: 302: 301: 299: 293: 289: 288: 285: 281: 279: 274: 273: 266: 265: 263: 261: 256: 255: 251: 247: 244: 242: 240:ECHA InfoCard 237: 236: 229: 225: 224: 222: 220: 217: 216: 209: 205: 204: 202: 200: 197: 196: 189: 185: 184: 182: 180: 177: 176: 169: 165: 164: 162: 158: 153: 152: 144: 140: 137: 132: 128: 127: 125: 122: 118: 117: 112: 104: 103: 98: 92: 88: 84: 80: 74: 70: 61: 57: 52: 48: 43: 39: 34: 23: 19: 1612: 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1229:236243315 1221:0959-6526 1164:218970877 1156:1872-2067 1115:0255-2701 1052:1432-0614 876:to treat 821:actinides 735:O → C 620:oxidation 267:208-401-4 259:EC Number 1571:17091088 1509:31275855 1060:17525864 1009:18330562 920:See also 852:Medicine 796:chelates 640:hydroxyl 501:316 g/L 277:E number 143:133-42-6 131:526-95-4 1579:3691306 1536:2741315 1500:6593216 1483:: 522. 1430:Bibcode 1348:Bibcode 1191:Bibcode 1095:Bibcode 1068:7700011 1017:2246466 904:malaria 896:Quinine 783:. As a 624:glucose 549:what is 547: ( 507:Acidity 469:196.155 328: ( 292:PubChem 134: ( 1577:  1569:  1534:  1507:  1497:  1456:  1448:  1401:  1366:  1266:  1227:  1219:  1162:  1154:  1113:  1066:  1058:  1050:  1015:  1007:  914:anemia 872:, and 835:neuter 779:, and 616:esters 598:(CHOH) 570:is an 544:verify 541:  413:SMILES 199:ChEMBL 54:Names 1575:S2CID 1454:S2CID 1225:S2CID 1160:S2CID 1064:S2CID 1013:S2CID 938:(ISA) 777:honey 773:fruit 755:. or 695:→ C 612:salts 574:with 519:3.86 378:InChI 305:10690 282:E574 228:10240 179:ChEBI 157:JSmol 1567:PMID 1532:PMID 1505:PMID 1446:ISSN 1399:ISSN 1364:ISSN 1264:ISSN 1217:ISSN 1152:ISSN 1111:ISSN 1056:PMID 1048:ISSN 1005:PMID 819:and 781:wine 731:+ H 707:+ H 691:+ O 670:and 634:The 594:HOCH 316:UNII 1597:doi 1559:doi 1495:PMC 1485:doi 1438:doi 1391:doi 1356:doi 1344:195 1323:doi 1256:doi 1207:hdl 1199:doi 1187:312 1142:doi 1103:doi 1091:104 1040:doi 997:doi 622:of 347:EPA 295:CID 20:or 1645:: 1573:. 1565:. 1555:27 1553:. 1528:31 1526:. 1503:. 1493:. 1479:. 1475:. 1452:. 1444:. 1436:. 1426:21 1424:. 1420:. 1397:. 1387:91 1385:. 1362:. 1354:. 1342:. 1291:91 1262:. 1223:. 1215:. 1205:. 1197:. 1185:. 1181:. 1158:. 1150:. 1138:41 1136:. 1132:. 1109:. 1101:. 1089:. 1085:. 1062:. 1054:. 1046:. 1036:75 1034:. 1011:. 1003:. 993:78 991:. 959:. 916:. 906:. 880:. 870:Fe 868:, 866:Cu 864:, 862:Ca 860:, 858:Zn 848:. 813:Al 811:, 805:, 803:Fe 801:, 799:Ca 791:. 775:, 741:12 725:10 701:10 685:12 602:CO 584:12 516:) 509:(p 451:12 89:,5 85:,4 81:,3 77:(2 1599:: 1581:. 1561:: 1538:. 1511:. 1487:: 1481:9 1460:. 1440:: 1432:: 1405:. 1393:: 1370:. 1358:: 1350:: 1325:: 1270:. 1258:: 1252:3 1231:. 1209:: 1201:: 1193:: 1166:. 1144:: 1117:. 1105:: 1097:: 1070:. 1042:: 1019:. 999:: 963:. 874:K 808:K 745:7 743:O 739:H 737:6 733:2 729:6 727:O 723:H 721:6 719:C 713:2 711:O 709:2 705:6 703:O 699:H 697:6 693:2 689:6 687:O 683:H 681:6 679:C 604:2 600:4 596:2 588:7 586:O 582:H 580:6 578:C 539:N 514:a 511:K 457:7 454:O 448:H 445:6 442:C 349:) 345:( 332:) 330:D 159:) 138:) 136:D 91:R 87:R 83:S 79:R 64:d 29:d 24:.

Index

Glucuronic acid
Glutaconic acid
Skeletal formula of gluconic acid
Ball-and-stick model of gluconic acid
IUPAC name
Systematic IUPAC name
CAS Number
526-95-4
133-42-6
JSmol
Interactive image
ChEBI
CHEBI:33198
ChEMBL
ChEMBL464345
ChemSpider
10240
ECHA InfoCard
100.007.639
Edit this at Wikidata
EC Number
E number
(acidity regulators, ...)
PubChem
10690
UNII
R4R8J0Q44B
CompTox Dashboard
DTXSID8027169
Edit this at Wikidata

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