Knowledge

Cardiovascular disease

Source πŸ“

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educational status or income are associated with a greater risk of cardiovascular disease. Policies that have resulted in increased socio-economic inequalities have been associated with greater subsequent socio-economic differences in cardiovascular disease implying a cause and effect relationship. Psychosocial factors, environmental exposures, health behaviours, and health-care access and quality contribute to socio-economic differentials in cardiovascular disease. The Commission on Social Determinants of Health recommended that more equal distributions of power, wealth, education, housing, environmental factors, nutrition, and health care were needed to address inequalities in cardiovascular disease and non-communicable diseases.
1489:, and although the role of dietary fat in cardiovascular disease is complex and controversial there is a long-standing consensus that replacing saturated fat with unsaturated fat in the diet is sound medical advice. Total fat intake has not been found to be associated with cardiovascular risk. A 2020 systematic review found moderate quality evidence that reducing saturated fat intake for at least 2 years caused a reduction in cardiovascular events. A 2015 meta-analysis of observational studies however did not find a convincing association between saturated fat intake and cardiovascular disease. Variation in what is used as a substitute for saturated fat may explain some differences in findings. The benefit from replacement with 418: 1234: 1803: 1306:
from the medication (higher risk). The number and variety of risk scores available for use has multiplied, but their efficacy according to a 2016 review was unclear due to lack of external validation or impact analysis. Risk stratification models often lack sensitivity for population groups and do not account for the large number of negative events among the intermediate and low risk groups. As a result, future preventative screening appears to shift toward applying prevention according to randomized trial results of each intervention rather than large-scale risk assessment.
52: 4833: 4726: 10434:"ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (writing committee to develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death): developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society" 720:. While the individual contribution of each risk factor varies between different communities or ethnic groups the overall contribution of these risk factors is very consistent. Some of these risk factors, such as age, sex or family history/genetic predisposition, are immutable; however, many important cardiovascular risk factors are modifiable by lifestyle change, social change, drug treatment (for example prevention of hypertension, hyperlipidemia, and diabetes). People with obesity are at increased risk of 1543:
differences between drugs in their ability to prevent specific outcomes. Larger reductions in blood pressure produce larger reductions in risk, and most people with high blood pressure require more than one drug to achieve adequate reduction in blood pressure. Adherence to medications is often poor, and while mobile phone text messaging has been tried to improve adherence, there is insufficient evidence that it alters secondary prevention of cardiovascular disease.
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fruit and vegetable consumption. Frequent consumption of high-energy foods, such as processed foods that are high in fats and sugars, promotes obesity and may increase cardiovascular risk. The amount of dietary salt consumed may also be an important determinant of blood pressure levels and overall cardiovascular risk. There is moderate quality evidence that reducing saturated fat intake for at least two years reduces the risk of cardiovascular disease. High
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not known to have cardiovascular disease. These measures, and sometimes others, may be combined into composite risk scores to estimate an individual's future risk of cardiovascular disease. Numerous risk scores exist although their respective merits are debated. Other diagnostic tests and biomarkers remain under evaluation but currently these lack clear-cut evidence to support their routine use. They include family history, coronary artery
780:, it has been argued that a woman's risk is similar to a man's although more recent data from the WHO and UN disputes this. If a female has diabetes, she is more likely to develop heart disease than a male with diabetes. Women who have high blood pressure and had complications in their pregnancy have three times the risk of developing cardiovascular disease compared to women with normal blood pressure who had no complications in pregnancy. 827:
were insufficiently physically active. The risk of ischemic heart disease and diabetes mellitus is reduced by almost a third in adults who participate in 150 minutes of moderate physical activity each week (or equivalent). In addition, physical activity assists weight loss and improves blood glucose control, blood pressure, lipid profile and insulin sensitivity. These effects may, at least in part, explain its cardiovascular benefits.
746: 7146: 787:, sex contributes to approximately 40% of the variation in sex ratios of coronary heart disease mortality. Another study reports similar results finding that sex differences explains nearly half the risk associated with cardiovascular diseases One of the proposed explanations for sex differences in cardiovascular diseases is hormonal difference. Among women, estrogen is the predominant sex hormone. 899:
Americans get less than the recommended seven hours of sleep per night, and in a study of teenagers, just 2.2 percent of those studied got enough sleep, many of whom did not get good quality sleep. Studies have shown that short sleepers getting less than seven hours sleep per night have a 10 percent to 30 percent higher risk of cardiovascular disease.
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cardiovascular disease that can be traced to a single disease-causing DNA variant, although these conditions are rare. Most common cardiovascular diseases are non-Mendelian and are thought to be due to hundreds or thousands of genetic variants (known as single nucleotide polymorphisms), each associated with a small effect.
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Proper CVD management necessitates a focus on MI and stroke cases due to their combined high mortality rate, keeping in mind the cost-effectiveness of any intervention, especially in developing countries with low or middle-income levels. Regarding MI, strategies using aspirin, atenolol, streptokinase
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intake has adverse effects on blood lipids and circulating inflammatory markers, and elimination of trans-fat from diets has been widely advocated. In 2018 the World Health Organization estimated that trans fats were the cause of more than half a million deaths per year. There is evidence that higher
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Age is the most important risk factor in developing cardiovascular or heart diseases, with approximately a tripling of risk with each decade of life. Coronary fatty streaks can begin to form in adolescence. It is estimated that 82 percent of people who die of coronary heart disease are 65 and older.
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DECODE, European Diabetes Epidemiology Group (August 1999). "Glucose tolerance and mortality: comparison of WHO and American Diabetes Association diagnostic criteria. The DECODE study group. European Diabetes Epidemiology Group. Diabetes Epidemiology: Collaborative analysis Of Diagnostic criteria in
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Blood pressure medication reduces cardiovascular disease in people at risk, irrespective of age, the baseline level of cardiovascular risk, or baseline blood pressure. The commonly-used drug regimens have similar efficacy in reducing the risk of all major cardiovascular events, although there may be
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production of aluminium or the production of paper when the sulphate pulping process is used is associated with heart disease. An association was also found between heart disease and exposure to compounds which are no longer permitted in certain work environments, such
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In addition, sleep research displays differences in race and class. Short sleep and poor sleep tend to be more frequently reported in ethnic minorities than in whites. African-Americans report experiencing short durations of sleep five times more often than whites, possibly as a result of social and
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High dietary intakes of saturated fat, trans-fats and salt, and low intake of fruits, vegetables and fish are linked to cardiovascular risk, although whether all these associations indicate causes is disputed. The World Health Organization attributes approximately 1.7 million deaths worldwide to low
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Multiple explanations are proposed to explain why age increases the risk of cardiovascular/heart diseases. One of them relates to serum cholesterol level. In most populations, the serum total cholesterol level increases as age increases. In men, this increase levels off around age 45 to 50 years. In
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Cardiovascular disease in a person's parents increases their risk by ~3 fold, and genetics is an important risk factor for cardiovascular diseases. Genetic cardiovascular disease can occur either as a consequence of single variant (Mendelian) or polygenic influences. There are more than 40 inherited
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Cardiovascular diseases are the leading cause of death worldwide and in all regions except Africa. In 2008, 30% of all global death was attributed to cardiovascular diseases. Death caused by cardiovascular diseases are also higher in low- and middle-income countries as over 80% of all global deaths
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A systematic review estimated that inactivity is responsible for 6% of the burden of disease from coronary heart disease worldwide. The authors estimated that 121,000 deaths from coronary heart disease could have been averted in Europe in 2008 if people had not been physically inactive. Low-quality
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Screening and selection for primary prevention interventions has traditionally been done through absolute risk using a variety of scores (ex. Framingham or Reynolds risk scores). This stratification has separated people who receive the lifestyle interventions (generally lower and intermediate risk)
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Existing cardiovascular disease or a previous cardiovascular event, such as a heart attack or stroke, is the strongest predictor of a future cardiovascular event. Age, sex, smoking, blood pressure, blood lipids and diabetes are important predictors of future cardiovascular disease in people who are
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since the 1970s. Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. Most cardiovascular disease affects older adults. In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80,
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The relationship between alcohol consumption and cardiovascular disease is complex, and may depend on the amount of alcohol consumed. There is a direct relationship between high levels of drinking alcohol and cardiovascular disease. Drinking at low levels without episodes of heavy drinking may be
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Antibiotics may help patients with coronary disease to reduce the risk of heart attacks and strokes. However, evidence in 2021 suggests that antibiotics for secondary prevention of coronary heart disease are harmful, with increased mortality and occurrence of stroke; the use of antibiotics is not
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are effective in preventing further cardiovascular disease in people with a history of cardiovascular disease. As the event rate is higher in men than in women, the decrease in events is more easily seen in men than women. In those at risk, but without a history of cardiovascular disease (primary
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is associated with higher rates of cardiovascular disease, and in 2015 the Food and Drug Administration (FDA) determined that there was 'no longer a consensus among qualified experts that partially hydrogenated oils (PHOs), which are the primary dietary source of industrially produced trans fatty
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Most guidelines recommend combining preventive strategies. There is some evidence that interventions aiming to reduce more than one cardiovascular risk factor may have beneficial effects on blood pressure, body mass index and waist circumference; however, evidence was limited and the authors were
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Cardiovascular disease has a greater impact on low- and middle-income countries compared to those with higher income. Although data on the social patterns of cardiovascular disease in low- and middle-income countries is limited, reports from high-income countries consistently demonstrate that low
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A lack of good sleep, in amount or quality, is documented as increasing cardiovascular risk in both adults and teens. Recommendations suggest that Infants typically need 12 or more hours of sleep per day, adolescent at least eight or nine hours, and adults seven or eight. About one-third of adult
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Insufficient physical activity (defined as less than 5 x 30 minutes of moderate activity per week, or less than 3 x 20 minutes of vigorous activity per week) is currently the fourth leading risk factor for mortality worldwide. In 2008, 31.3% of adults aged 15 or older (28.2% men and 34.4% women)
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Among men and women, there are differences in body weight, height, body fat distribution, heart rate, stroke volume, and arterial compliance. In the very elderly, age-related large artery pulsatility and stiffness are more pronounced among women than men. This may be caused by the women's smaller
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in people with high or normal blood pressure are not clear. In those with heart failure, after one study was left out, the rest of the trials show a trend to benefit. Another review of dietary salt concluded that there is strong evidence that high dietary salt intake increases blood pressure and
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can provide a risk reduction for CVD if a healthy plant-based diet is consumed. Unhealthy plant-based diets do not provide benefits over diets including meat. A similar meta-analysis and systematic review also looked into dietary patterns and found "that diets lower in animal foods and unhealthy
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There is additional evidence to suggest that providing people with a cardiovascular disease risk score may reduce risk factors by a small amount compared to usual care. However, there was some uncertainty as to whether providing these scores had any effect on cardiovascular disease events. It is
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Limit alcohol consumption to the recommended daily limits. People who moderately consume alcoholic drinks have a 25–30% lower risk of cardiovascular disease. However, people who are genetically predisposed to consume less alcohol have lower rates of cardiovascular disease suggesting that alcohol
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There is evidence that mental health problems, in particular depression and traumatic stress, is linked to cardiovascular diseases. Whereas mental health problems are known to be associated with risk factors for cardiovascular diseases such as smoking, poor diet, and a sedentary lifestyle, these
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Cigarettes are the major form of smoked tobacco. Risks to health from tobacco use result not only from direct consumption of tobacco, but also from exposure to second-hand smoke. Approximately 10% of cardiovascular disease is attributed to smoking; however, people who quit smoking by age 30 have
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Czernichow S, Zanchetti A, Turnbull F, Barzi F, Ninomiya T, Kengne AP, et al. (January 2011). "The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: meta-analysis of randomized trials".
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with healthier choices: Clinical trials show that replacing saturated fat with polyunsaturated vegetable oil reduced CVD by 30%. Prospective observational studies show that in many populations lower intake of saturated fat coupled with higher intake of polyunsaturated and monounsaturated fat is
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Exercise-based cardiac rehabilitation following a heart attack reduces the risk of death from cardiovascular disease and leads to less hospitalizations. There have been few high-quality studies of the benefits of exercise training in people with increased cardiovascular risk but no history of
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Decrease body fat if overweight or obese. The effect of weight loss is often difficult to distinguish from dietary change, and evidence on weight reducing diets is limited. In observational studies of people with severe obesity, weight loss following bariatric surgery is associated with a 46%
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Population-based studies show that atherosclerosis, the major precursor of cardiovascular disease, begins in childhood. The Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study demonstrated that intimal lesions appear in all the aortas and more than half of the right coronary
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can increase the risk of heart disease and death, as observed in breast cancer therapy. Therapeutic radiation increases the risk of a subsequent heart attack or stroke by 1.5 to 4 times; the increase depends on the dose strength, volume, and location. Use of concomitant chemotherapy, e.g.
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It is estimated that 60% of the world's cardiovascular disease burden will occur in the South Asian subcontinent despite only accounting for 20% of the world's population. This may be secondary to a combination of genetic predisposition and environmental factors. Organizations such as the
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prevention), statins decrease the risk of death and combined fatal and non-fatal cardiovascular disease. The benefit, however, is small. A United States guideline recommends statins in those who have a 12% or greater risk of cardiovascular disease over the next ten years.
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has been found to be of only modest benefit in those at low risk of heart disease, as the risk of serious bleeding is almost equal to the protection against cardiovascular problems. In those at very low risk, including those over the age of 70, it is not recommended. The
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associated with a reduced risk of cardiovascular disease, but there is evidence that associations between moderate alcohol consumption and protection from stroke are non-causal. At the population level, the health risks of drinking alcohol exceed any potential benefits.
7678:"Global, regional, and national burdens of ischemic heart disease and stroke attributable to exposure to long working hours for 194 countries, 2000–2016: A systematic analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury" 5724:"Assessment of the 12-lead ECG as a screening test for detection of cardiovascular disease in healthy general populations of young people (12-25 Years of Age): a scientific statement from the American Heart Association and the American College of Cardiology" 1921:
There is evidence that cardiovascular disease existed in pre-history, and research into cardiovascular disease dates from at least the 18th century. The causes, prevention, and/or treatment of all forms of cardiovascular disease remain active fields of
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Jackson R, Chambles L, Higgins M, Kuulasmaa K, Wijnberg L, Williams D (WHO MONICA Project, and ARIC Study.) Sex difference in ischaemic heart disease mortality and risk factors in 46 communities: an ecologic analysis. Cardiovasc Risk Factors. 1999;
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and 85% of people over 80 have CVD. The average age of death from coronary artery disease in the developed world is around 80, while it is around 68 in the developing world. CVD is typically diagnosed seven to ten years earlier in men than in women.
1270:(either at rest or with exercise) are not recommended in those without symptoms who are at low risk. This includes those who are young without risk factors. In those at higher risk the evidence for screening with ECGs is inconclusive. Additionally 1030:
Little is known about the relationship between work and cardiovascular disease, but links have been established between certain toxins, extreme heat and cold, exposure to tobacco smoke, and mental health concerns such as stress and depression.
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The NIH recommends lipid testing in children beginning at the age of 2 if there is a family history of heart disease or lipid problems. It is hoped that early testing will improve lifestyle factors in those at risk such as diet and exercise.
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Not enough sleep also raises the risk of high blood pressure. Adults need about 7–9 hours of sleep. Sleep apnea is also a major risk as it causes breathing to stop briefly, which can put stress on the body which can raise the risk of heart
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was also increased by exposure to ionizing radiation. Hypertension develops more often in those who experience job strain and who have shift-work. Differences between women and men in risk are small, however men risk having and dying of
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Aging is also associated with changes in the mechanical and structural properties of the vascular wall, which leads to the loss of arterial elasticity and reduced arterial compliance and may subsequently lead to coronary artery disease.
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evidence from a limited number of studies suggest that yoga has beneficial effects on blood pressure and cholesterol. Tentative evidence suggests that home-based exercise programs may be more efficient at improving exercise adherence.
370:, among other things. High blood pressure is estimated to account for approximately 13% of CVD deaths, while tobacco accounts for 9%, diabetes 6%, lack of exercise 6%, and obesity 5%. Rheumatic heart disease may follow untreated 1237:
Density-Dependent Colour Scanning Electron Micrograph SEM (DDC-SEM) of cardiovascular calcification, showing in orange calcium phosphate spherical particles (denser material) and, in green, the extracellular matrix (less dense
624:, the muscular part of the heart, caused most often by viral infection and less often by bacterial infections, certain medications, toxins, and autoimmune disorders. It is characterized in part by infiltration of the heart by 1409:
affects their risk of cardiovascular disease. According to a 2021 WHO study, working 55+ hours a week raises the risk of stroke by 35% and the risk of dying from heart conditions by 17%, when compared to a 35-40 hours week.
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do not affect the risk of cardiovascular disease in those who are already on statins. Fibrates lower the risk of cardiovascular and coronary events, but there is no evidence to suggest that they reduce all-cause mortality.
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Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, et al. (2004). "Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study".
950:) are the major focus, in which gradients are used to determine CVD risk. Overall, long-term PM exposure increased rate of atherosclerosis and inflammation. In regards to short-term exposure (2 hours), every 25 ΞΌg/m of PM 1354:
itself may not be protective. Excessive alcohol intake increases the risk of cardiovascular disease and consumption of alcohol is associated with increased risk of a cardiovascular event in the day following consumption.
10475:"Efficacy of omega-3 fatty acid supplements (eicosapentaenoic acid and docosahexaenoic acid) in the secondary prevention of cardiovascular disease: a meta-analysis of randomized, double-blind, placebo-controlled trials" 8410:
Chowdhury R, Warnakula S, Kunutsor S, Crowe F, Ward HA, Johnson L, et al. (March 2014). "Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis".
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may also lead to increased risk of cardiovascular disease. Several large-scale research projects looking at human genetic data have found a robust link between the presence of these mutations, a condition known as
5065: 5023: 11049: 11034: 1141:. There is evidence that workplace exposure to lead, carbon disulphide, phenoxyacids containing TCDD, as well as working in an environment where aluminum is being electrolytically produced, is associated with 7397:
Dickinson HO, Mason JM, Nicolson DJ, Campbell F, Beyer FR, Cook JV, et al. (February 2006). "Lifestyle interventions to reduce raised blood pressure: a systematic review of randomized controlled trials".
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McMahan CA, Gidding SS, Malcom GT, Tracy RE, Strong JP, McGill HC (October 2006). "Pathobiological determinants of atherosclerosis in youth risk scores are associated with early and advanced atherosclerosis".
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McNeal CJ, Dajani T, Wilson D, Cassidy-Bushrow AE, Dickerson JB, Ory M (January 2010). "Hypercholesterolemia in youth: opportunities and obstacles to prevent premature atherosclerotic cardiovascular disease".
381:, exercise, avoidance of tobacco smoke and limiting alcohol intake. Treating risk factors, such as high blood pressure, blood lipids and diabetes is also beneficial. Treating people who have strep throat with 333:
The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve
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25, streptokinase was about $ 680, and t-PA was $ 16,000. Aspirin, ACE inhibitors, beta-blockers, and statins used together for secondary CVD prevention in the same regions showed single QALY costs of $ 350.
7084:"expert reaction to study looking at pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure | Science Media Centre" 6553:
Kwok CS, Pradhan A, Khan MA, Anderson SG, Keavney BD, Myint PK, et al. (April 2014). "Bariatric surgery and its impact on cardiovascular disease and mortality: a systematic review and meta-analysis".
3991:"Sugar and cardiovascular disease: A statement for healthcare professionals from the Committee on Nutrition of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association" 2167:"Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015" 1258:. In fact, cardiovascular disease is the most life-threatening of the diabetic complications and diabetics are two- to four-fold more likely to die of cardiovascular-related causes than nondiabetics. 10759:
Thompson RC, Allam AH, Lombardi GP, Wann LS, Sutherland ML, Sutherland JD, et al. (April 2013). "Atherosclerosis across 4000 years of human history: the Horus study of four ancient populations".
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probably through other mechanisms. Moderate evidence was found that high salt intake increases cardiovascular mortality; and some evidence was found for an increase in overall mortality, strokes, and
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may reduce cardiovascular risk in people with Type 2 diabetes, although evidence is not conclusive. A meta-analysis in 2009 including 27,049 participants and 2,370 major vascular events showed a 15%
9113:"An effective approach to high blood pressure control: a science advisory from the American Heart Association, the American College of Cardiology, and the Centers for Disease Control and Prevention" 7106:"Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis" 954:
resulted in a 48% increase of CVD mortality risk. In addition, after only 5 days of exposure, a rise in systolic (2.8 mmHg) and diastolic (2.7 mmHg) blood pressure occurred for every 10.5 ΞΌg/m of PM
9607: 9747: 9388:"Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients" 5561:
Kvan E, Pettersen KI, Sandvik L, Reikvam A (October 2007). "High mortality in diabetic patients with acute myocardial infarction: cardiovascular co-morbidities contribute most to the high risk".
9635:"2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines" 8311:"Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies" 1701:
or tissue plasminogen activator have been compared for quality-adjusted life-year (QALY) in regions of low and middle income. The costs for a single QALY for aspirin and atenolol were less than
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Chou R (March 2015). "Cardiac screening with electrocardiography, stress echocardiography, or myocardial perfusion imaging: advice for high-value care from the American College of Physicians".
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There are also surgical or procedural interventions that can save someone's life or prolong it. For heart valve problems, a person could have surgery to replace the valve. For arrhythmias, a
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consumption of sugar is associated with higher blood pressure and unfavorable blood lipids, and sugar intake also increases the risk of diabetes mellitus. High consumption of processed meats
2115:"Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013" 1377:
Lower blood pressure, if elevated. A 10 mmHg reduction in blood pressure reduces risk by about 20%. Lowering blood pressure appears to be effective even at normal blood pressure ranges.
9347:"Management of dyslipidemia for cardiovascular disease risk reduction: synopsis of the 2014 U.S. Department of Veterans Affairs and U.S. Department of Defense clinical practice guideline" 1645:, etc.) or vitamins has not been shown to protect against cardiovascular disease and in some cases may possibly result in harm. Mineral supplements have also not been found to be useful. 1474:(high in nuts, fish, fruits and vegetables, and low in sweets, red meat and fat) has been shown to reduce blood pressure, lower total and low density lipoprotein cholesterol and improve 6840:"Endothelial function in healthy 11-year-old children after dietary intervention with onset in infancy: the Special Turku Coronary Risk Factor Intervention Project for children (STRIP)" 8974:
Blood Pressure Lowering Treatment Trialists' Collaboration (August 2014). "Blood pressure-lowering treatment based on cardiovascular risk: a meta-analysis of individual patient data".
7443:"Effectiveness of mindfulness-based stress reduction and mindfulness based cognitive therapy in vascular disease: A systematic review and meta-analysis of randomised controlled trials" 903: 13693: 7305:
Pelliccia F, Greco C, Vitale C, Rosano G, Gaudio C, Kaski JC (August 2014). "Takotsubo syndrome (stress cardiomyopathy): an intriguing clinical condition in search of its identity".
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There is probably no additional benefit in terms of mortality and serious adverse events when blood pressure targets were lowered to ≀ 135/85 mmHg from ≀ 140 to 160/90 to 100 mmHg.
8069:"Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis" 7745:"Fruit and vegetable consumption and mortality from all causes, cardiovascular disease, and cancer: systematic review and dose-response meta-analysis of prospective cohort studies" 10276:"Vitamin and mineral supplements in the primary prevention of cardiovascular disease and cancer: An updated systematic evidence review for the U.S. Preventive Services Task Force" 3429: 1929:
Recent areas of research include the link between inflammation and atherosclerosis the potential for novel therapeutic interventions, and the genetics of coronary heart disease.
5598:"Diabetes mellitus: the major risk factor in unstable coronary artery disease even after consideration of the extent of coronary artery disease and benefits of revascularization" 8169: 1388:
is associated with an increased risk of heart problems in those with previous heart disease. Severe emotional and physical stress leads to a form of heart dysfunction known as
14359: 5069: 5035: 4040:"Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records" 1534:
could prevent cardiovascular disease. Intermittent fasting may help people lose more weight than regular eating patterns, but was not different from energy restriction diets.
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Remig V, Franklin B, Margolis S, Kostas G, Nece T, Street JC (April 2010). "Trans fats in America: a review of their use, consumption, health implications, and regulation".
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who experience low social support at work; who experience injustice or experience insufficient opportunities for personal development; or those who experience job insecurity
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caused by cardiovascular diseases occurred in those countries. It is also estimated that by 2030, over 23 million people will die from cardiovascular diseases each year.
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Up to 90% of cardiovascular disease may be preventable if established risk factors are avoided. Currently practised measures to prevent cardiovascular disease include:
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Bruckert E, Labreuche J, Amarenco P (June 2010). "Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis".
8028:"Cereal Fibre Intake and Risk of Mortality From All Causes, CVD, Cancer and Inflammatory Diseases: A Systematic Review and Meta-Analysis of Prospective Cohort Studies" 795:
cell function. The production of estrogen decreases after menopause, and this may change the female lipid metabolism toward a more atherogenic form by decreasing the
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Di Cesare M, Khang YH, Asaria P, Blakely T, Cowan MJ, Farzadfar F, et al. (February 2013). "Inequalities in non-communicable diseases and effective responses".
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may add to conventional cardiovascular risk factors in predicting the risk of future cardiovascular disease; however, the value of some biomarkers is questionable.
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Food Drug Administration H (May 2018). "Final Determination Regarding Partially Hydrogenated Oils. Notification; declaratory order; extension of compliance date".
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Closing the Gap in a Generation: Health Equity Through Action on the Social Determinants of Health : Commission on Social Determinants of Health Final Report
2723: 14711: 13686: 10178:"Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials" 9572:(July 2011). "Aspirin for the prevention of cardiovascular events in patients without clinical cardiovascular disease: a meta-analysis of randomized trials". 7848: 11783: 5539: 1502:
acids (IP-TFA), are generally recognized as safe (GRAS) for any use in human food'. There is conflicting evidence concerning whether dietary supplements of
8826:"Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP)" 7864:"Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group" 6305:"Association between Plant-Based Dietary Patterns and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies" 3950:"Dietary sugars and cardiometabolic risk: systematic review and meta-analyses of randomized controlled trials of the effects on blood pressure and lipids" 3075:
Eckel RH (November 1997). "Obesity and heart disease: a statement for healthcare professionals from the Nutrition Committee, American Heart Association".
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Spence JD (November 2006). "Technology Insight: ultrasound measurement of carotid plaque--patient management, genetic research, and therapy evaluation".
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Clark AM, DesMeules M, Luo W, Duncan AS, Wielgosz A (November 2009). "Socioeconomic status and cardiovascular disease: risks and implications for care".
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recommends against use of aspirin for prevention in women less than 55 and men less than 45 years old; however, it is recommended for some older people.
9066:"Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials" 7519: 5448:
Vanhecke TE, Miller WM, Franklin BA, Weber JE, McCullough PA (October 2006). "Awareness, knowledge, and perception of heart disease among adolescents".
8629: 3607: 10738: 8927:"Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials" 2527:"Aspirin in primary prevention of cardiovascular disease and cancer: a systematic review of the balance of evidence from reviews of randomized trials" 13679: 2423:"Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study" 2974: 2091: 4274:"Sleep Duration and Quality: Impact on Lifestyle Behaviors and Cardiometabolic Health: A Scientific Statement From the American Heart Association" 6243:"The Association of Plant-Based Diet With Cardiovascular Disease and Mortality: A Meta-Analysis and Systematic Review of Prospect Cohort Studies" 3491:"Sex, age, cardiovascular risk factors, and coronary heart disease: a prospective follow-up study of 14 786 middle-aged men and women in Finland" 3673:"Association Between Chronic Hypertension and the Risk of 12 Cardiovascular Diseases Among Parous Women: The Role of Adverse Pregnancy Outcomes" 3430:
http://www.heart.org/HEARTORG/Conditions/HeartAttack/UnderstandYourRiskofHeartAttack/Understand-Your-Risk-of-Heart-Attack_UCM_002040_Article.jsp
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Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, et al. (GBD 2015 Mortality and Causes of Death Collaborators) (October 2016).
1448:
concluded that "In most countries, a vegan diet is associated with a more favourable cardio-metabolic profile compared to an omnivorous diet."
1016:
is independently associated with increased risk for incident coronary heart disease, even after adjusting for depression and other covariates.
8532:"Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks: Meta-analysis of 10 Trials Involving 77 917 Individuals" 6881:"Statins for Prevention of Cardiovascular Disease in Adults: Evidence Report and Systematic Review for the US Preventive Services Task Force" 1577:
in cardiovascular disease with more-intensive glucose lowering over an average follow-up period of 4.4 years, but an increased risk of major
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1514:
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1182:
anthracyclines, is an aggravating risk factor. The occurrence rate of RT induced cardiovascular disease is estimated between 10% and 30%.
14875: 13384: 13374: 12209: 5941:"Risk Assessment for Cardiovascular Disease With Nontraditional Risk Factors: US Preventive Services Task Force Recommendation Statement" 4675:"Prediction of cardiovascular risk using Framingham, ASSIGN and QRISK2: how well do they predict individual rather than population risk?" 2382:"Preventing heart disease in the 21st century: implications of the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study" 1599:
agents for people with pulmonary hypertension with left heart disease or hypoxemic lung diseases may cause harm and unnecessary expense.
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in some people. Stress, however, plays a relatively minor role in hypertension. Specific relaxation therapies are of unclear benefit.
5295:"Out of the frying pan and into the fire: damage-associated molecular patterns and cardiovascular toxicity following cancer therapy" 5077: 5027: 4138:"Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China" 1653:
supplementation lowers high blood pressure in a dose-dependent manner. Magnesium therapy is recommended for people with ventricular
14882: 14366: 11114: 10227:"Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis" 8694:"Normal-sodium diet compared with low-sodium diet in compensated congestive heart failure: is sodium an old enemy or a new friend?" 7258:"Meta-analysis of mental stress-induced myocardial ischemia and subsequent cardiac events in patients with coronary artery disease" 1423: 9930:"Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy" 3593: 3331:"Mortality from ischaemic heart disease by country, region, and age: statistics from World Health Organisation and United Nations" 696:
consumption, unhealthy diet, obesity, genetic predisposition and family history of cardiovascular disease, raised blood pressure (
922:
environmental factors. Black children and children living in disadvantaged neighborhoods have much higher rates of sleep apnea.
7058: 5982:"Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report" 5683:"Screening for Cardiovascular Disease Risk With Electrocardiography: US Preventive Services Task Force Recommendation Statement" 2824:"Unprocessed red and processed meats and risk of coronary artery disease and type 2 diabetes--an updated review of the evidence" 2673:"Temporal trends in ischemic heart disease mortality in 21 world regions, 1980 to 2010: the Global Burden of Disease 2010 study" 1713:
can be put in place to help reduce abnormal heart rhythms and for a heart attack, there are multiple options two of these are a
1384:. This measure may be complicated by imprecise definitions of what constitute psychosocial interventions. Mental stress–induced 14808: 14731: 13364: 11841: 11158: 6704:"Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data" 2590: 2080:. World Health Organization in collaboration with the World Heart Federation and the World Stroke Organization. pp. 3–18. 1649:, a type of vitamin B3, may be an exception with a modest decrease in the risk of cardiovascular events in those at high risk. 1012:
factors alone do not explain the increased risk of cardiovascular diseases seen in depression, stress, and anxiety. Moreover,
12554: 10642: 8179: 6084: 5765:"Screening for coronary heart disease with electrocardiography: U.S. Preventive Services Task Force recommendation statement" 4741:"Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association" 4653: 4482: 4196: 3782: 3460: 3059: 2754: 2651: 2085: 396:
worldwide except Africa. Together CVD resulted in 17.9 million deaths (32.1%) in 2015, up from 12.3 million (25.8%) in 1990.
10658: 4659: 4202: 1946: 890:
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in irregular heart rhythm, reduced heart rate variability (decreased vagal tone), and most notably heart failure. PM
689: 377:
It is estimated that up to 90% of CVD may be preventable. Prevention of CVD involves improving risk factors through:
9686:"Aspirin for the prevention of cardiovascular disease: U.S. Preventive Services Task Force recommendation statement" 14970: 13593: 13568: 13359: 12709: 12326: 11813: 9771:
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Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association, 15 Jun 2017,
5064: 1455:
may improve cardiovascular outcomes. There is also evidence that a Mediterranean diet may be more effective than a
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Cardiovascular disease is treatable with initial treatment primarily focused on diet and lifestyle interventions.
1043:
with mentally stressful work with a lack of control over their working situation β€” with an effort-reward imbalance
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Coronary heart diseases are 2 to 5 times more common among middle-aged men than women. In a study done by the
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plant foods, and higher in healthy plant foods are beneficial for CVD prevention". A 2018 meta-analysis of
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1389: 1323: 939: 646:
white blood cells. This disorder differs from myocarditis in its causes and treatments.
363: 95: 14830: 11058: 10772: 10450: 10433: 10409: 10392: 9945: 9497: 9081: 8987: 8648: 7121: 7035: 7018: 6856: 6839: 6670: 5651: 4756: 4564: 4339: 4153: 3748: 3723: 3689: 3672: 3644:(Plain English summary). National Institute for Health and Care Research. 2023-11-21. 3291: 3275:"The Future of Genetics and Genomics: Closing the Phenotype Gap in Precision Medicine" 3002: 2688: 2438: 2398: 2381: 2278:"Sleep as a potential fundamental contributor to disparities in cardiovascular health" 2182: 2130: 1432:
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There are many cardiovascular diseases involving the blood vessels. They are known as
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5344:"Radiation-Induced Cardiovascular Disease: Review of an Underrecognized Pathology" 4883:"State of the Art Review: Depression, Stress, Anxiety, and Cardiovascular Disease" 4089:"Alcohol consumption and cardiovascular mortality among U.S. adults, 1987 to 2002" 3724:"Mortality in relation to smoking: 50 years' observations on male British doctors" 3447:. World Health Organization and U. S. Centers for Disease Control and Prevention. 2422: 1039:
A 2015 SBU-report looking at non-chemical factors found an association for those:
859:
of cardiovascular disease, possibly in part due to increased dietary salt intake.
14461: 14435: 14268: 14240: 14201: 14145: 14138: 14121: 14083: 14049: 13605: 13391: 13283: 13203: 12827: 12822: 12734: 12457: 12412: 12292: 12171: 11563: 11544: 11531: 11338: 11217: 11092: 11069: 10845:"Inflammatory processes in cardiovascular disease: a route to targeted therapies" 9742: 9738: 9129: 9031: 8547: 8379: 8362: 8121:"Dietary Fat and Cardiovascular Disease: Ebb and Flow Over the Last Half Century" 7836: 7702: 7318: 6567: 6391: 6123: 6047: 6030: 5740: 5723: 5574: 5162: 5066:
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5024:
Swedish Agency for Health Technology Assessment and Assessment of Social Services
4699: 4643: 4289: 4218:"Objective Sleep Characteristics and Cardiometabolic Health in Young Adolescents" 4186: 3864: 3346: 2943: 2926: 2551: 1980: 1912: 1563: 1559: 1185:
Side-effects from radiation therapy for cardiovascular diseases have been termed
1106: 915: 721: 666: 543: 405: 343: 335: 315: 275: 112: 10080:"Vitamin C supplementation for the primary prevention of cardiovascular disease" 8942: 8841: 8579:
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8250:
Hooper L, Martin N, Jimoh OF, Kirk C, Foster E, Abdelhamid AS (21 August 2020).
7880: 7863: 4136:
Millwood IY, Walters RG, Mei XW, Guo Y, Yang L, Bian Z, et al. (May 2019).
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in bringing about long-term changes to cardiovascular risk factors (e.g., lower
14556: 14079: 14074: 13997: 13949: 13230: 12876: 12726: 12589: 12549: 12484: 12445: 12356: 12164: 12072: 11970: 11962: 11860: 11370: 11363: 11350: 11080: 10532: 10515: 10368: 10351: 9651: 7962: 7945: 7150: 5614: 5597: 5201: 4104: 3899: 3649: 3442: 3182: 3165: 3128: 2772:"Key articles of dietary interventions that influence cardiovascular mortality" 2639: 2637: 1464: 1371:
and avoidance of second-hand smoke. Stopping smoking reduces risk by about 35%.
1251: 1194: 1090: 1078: 967: 883: 709: 705: 693: 563: 553: 378: 295: 215: 199: 188: 180: 160: 71: 11043: 10954: 10909: 10860: 10144: 9585: 9545: 9528: 8788: 8136: 8044: 8027: 6189: 4947: 4859: 4441: 2839: 776:
Men are at greater risk of heart disease than pre-menopausal women. Once past
581:– a failure at the right side of the heart with respiratory system involvement 14959: 14648: 14305: 14261: 14234: 13859: 13772: 13722: 13169: 13009: 12744: 12407: 12154: 12065: 11200: 10993:
2021 ESC Guidelines on cardiovascular disease prevention in clinical practice
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Al Khalaf S, Chappell LC, Khashan AS, McCarthy FP, O'Reilly Γ‰J (July 2023).
3380:"Atherogenic dyslipidemia and cardiovascular risk factors in obese children" 1374:
At least 150 minutes (2 hours and 30 minutes) of moderate exercise per week.
14691: 14630: 14625: 14597: 14425: 14402: 14150: 14069: 13927: 13779: 13752: 13744: 13289: 13130: 12885: 12797: 12612: 12302: 12245: 12086: 12060: 11904: 11852: 11525: 11501: 11448: 11307: 10962: 10927: 10878: 10780: 10719: 10606: 10549: 10500: 10459: 10418: 10377: 10336: 10301: 10252: 10211: 10176:
Myung SK, Ju W, Cho B, Oh SW, Park SM, Koo BK, et al. (January 2013).
10162: 10129:"Coronary heart disease prevention: nutrients, foods, and dietary patterns" 10113: 10064: 10015: 9963: 9914: 9865: 9806: 9711: 9670: 9593: 9554: 9505: 9470: 9434: 9421: 9372: 9301: 9249: 9205: 9163: 9148: 9089: 9039: 8995: 8960: 8911: 8859: 8751: 8720: 8656: 8614: 8565: 8516: 8467: 8432: 8388: 8344: 8295: 8228: 8154: 8102: 8053: 8012: 7971: 7944:
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Ciaccio EJ, Lewis SK, Biviano AB, Iyer V, Garan H, Green PH (August 2017).
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8789:"Dietary Salt Intake and Cardiovascular Disease: Summarizing the Evidence" 7184: 5253: 3396: 3096: 2892: 1085:
is associated with heart disease. Associations also exist for exposure to
14484: 14479: 14098: 14060: 13986: 13884: 13879: 13849: 13701: 13633: 13535: 13401: 13103: 12950: 12346: 12021: 11919: 11709: 11626: 11608: 11434: 11407: 11358: 11299: 11000: 10391:
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9529:"Intensive glucose control and macrovascular outcomes in type 2 diabetes" 6473: 6456: 5909: 5865: 5848: 4898: 1926:, with hundreds of scientific studies being published on a weekly basis. 1634: 1530:
Overall, the current body of scientific evidence is uncertain on whether
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Hajishafiee M, Saneei P, Benisi-Kohansal S, Esmaillzadeh A (July 2016).
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6506:"Long-term effects of weight-reducing diets in people with hypertension" 4930:
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8805: 8755:. If this is an intentional citation to a such a paper, please replace 8712: 7469: 6321: 5235: 4348: 3452: 3011: 2232: 1596: 1282:
is not recommended in those at low risk who do not have symptoms. Some
1162: 992: 625: 621: 382: 323: 299: 226: 164: 100: 88: 59: 11026: 9746:, American College of Chest Physicians and American Thoracic Society, 9403: 8326: 8084: 7760: 7365: 7208:"Psychosocial interventions in cardiovascular disease--what are they?" 6764: 6719: 6241:
Quek J, Lim G, Lim WH, Ng CH, So WZ, Toh J, et al. (2021-11-05).
6143: 6077:
Braunwald's heart disease : a textbook of cardiovascular medicine
4549:"Cardiovascular effects of ambient particulate air pollution exposure" 3377: 1137:
Workplace exposure to silica dust or asbestos is also associated with
803:
body size and arterial dimensions which are independent of menopause.
754:
Simultaneously, the risk of stroke doubles every decade after age 55.
531:– a disease of blood vessels that supply blood to the brain (includes 14384: 13932: 13546: 13005: 12620: 12361: 12297: 12253: 12236: 12231: 10031:"Home versus center based physical activity programs in older adults" 9878: 9363: 9346: 8424: 6616: 6576: 5817: 5416: 4055: 3908: 2603: 2585: 1690: 1650: 1642: 1638: 1471: 946:. Currently, airborne particles under 2.5 micrometers in diameter (PM 851: 799:
cholesterol level while increasing LDL and total cholesterol levels.
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Ye Z, Cao Y, Miao C, Liu W, Dong L, Lv Z, et al. (2022-10-04).
6837: 5595: 5293:
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3241: 1298:, are also of unclear benefit in those without symptoms as of 2018. 642:– inflammation of the myocardium caused by pathologically activated 549:
There are also many cardiovascular diseases that involve the heart.
424:
for inflammatory heart diseases per 100,000 inhabitants in 2004
14255: 13757: 13339: 12834: 12436: 12373: 12307: 12258: 11975: 11132: 10571:
Clar C, Oseni Z, Flowers N, Keshtkar-Jahromi M, Rees K (May 2015).
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7572:"Risk scoring for the primary prevention of cardiovascular disease" 3488: 3428:"Understand Your Risk of Heart Attack". American Heart Association. 1555: 1331: 1158: 1154: 1131: 1098: 907: 788: 629: 525:– a disease of blood vessels that supply blood to the arms and legs 400:, from CVD are more common and have been increasing in much of the 311: 219: 176: 67: 9822:"Exercise-based cardiac rehabilitation for coronary heart disease" 9437:"Fibrates for primary prevention of cardiovascular disease events" 7943: 7818: 5238:"Recognizing Radiation Therapy–related Complications in the Chest" 4790:"Update on the NCEP ATP-III emerging cardiometabolic risk factors" 4037: 1250:
are linked to cardiovascular disease, as are a history of chronic
745: 13062: 10133:
Clinica Chimica Acta; International Journal of Clinical Chemistry
9683: 8786: 8174:. Rome: Food and Agriculture Organization of the United Nations. 6444:
https://www.ahajournals.org/doi/full/10.1161/CIR.0000000000000510
6174: 5292: 4848:
Clinica Chimica Acta; International Journal of Clinical Chemistry
3608:"Diabetes raises women's risk of heart disease more than for men" 2470:"Antibiotics for treatment of sore throat in children and adults" 2420: 1584: 1546: 1086: 386: 355: 231: 184: 108: 10570: 9773:"Antibiotics for secondary prevention of coronary heart disease" 9016: 8168:
Food and Agriculture Organization of the United Nations (2010).
6879:
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5450:
European Journal of Cardiovascular Prevention and Rehabilitation
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1482:
diet is associated with lower risks of cardiovascular disease.
758:
women, the increase continues sharply until age 60 to 65 years.
14407: 14192: 14162: 13727: 13066: 12227: 12055: 12035: 11190: 11038: 9526: 8409: 4738: 4379:
Mackenbach JP, Cavelaars AE, Kunst AE, Groenhof F (July 2000).
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Klatsky AL (May 2009). "Alcohol and cardiovascular diseases".
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3804:"Reduction in saturated fat intake for cardiovascular disease" 1603:
Antibiotics for secondary prevention of coronary heart disease
1170:, and cardiovascular disease-related incidents and mortality. 970:
thickening and increased risk of acute myocardial infarction.
14689: 13871: 13854: 13450: 13197: 10516:"Micronutrient supplementation to reduce cardiovascular risk" 9632: 8480: 7145: 6503: 5390: 5151:
International Journal of Radiation Oncology, Biology, Physics
4929: 2583: 2524: 2074:
Global Atlas on Cardiovascular Disease Prevention and Control
1693:
may make heart attacks and strokes more likely and therefore
1433: 717: 385:
can decrease the risk of rheumatic heart disease. The use of
367: 263: 63: 10843:
Ruparelia N, Chai JT, Fisher EA, Choudhury RP (March 2017).
10842: 8691: 5721: 3163: 2718: 2716: 1736:
Cardiovascular diseases deaths per million persons in 2012
1497:
does not appear to have a beneficial effect. A diet high in
1493:
appears greatest, while replacement of saturated fats with
1073:
A 2017 SBU report found evidence that workplace exposure to
712:, psychosocial factors, poverty and low educational status, 14292: 12603: 10631:
Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF (2018).
9979:"Yoga for the primary prevention of cardiovascular disease" 9770: 9221: 9110: 8875: 8308: 6701: 5560: 5447: 4672: 4325: 3947: 3885: 3440: 1702: 1608:
supported for preventing secondary coronary heart disease.
1094: 389:
in people who are otherwise healthy is of unclear benefit.
10573:"Influenza vaccines for preventing cardiovascular disease" 10028: 9976: 9819: 9385: 8924: 8529: 7304: 7103: 6652: 6598: 6075:
Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E (2014).
4271: 3948:
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3441:
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2670: 1962: 1478:; but the long-term benefits have been questioned. A high- 1049:
those who work night schedules; or have long working weeks
10758: 10314: 8823: 8578: 7902: 7016: 6793: 4641: 4470: 4184: 3721: 2713: 1267: 27:
Class of diseases that involve the heart or blood vessels
10808:
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10675: 10431: 9386:
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9262: 9222:
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8787:
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Institute of Medicine of the National Academies (2010).
1365:
treatment reduces cardiovascular mortality by about 31%.
10735:"Cardiac Disease Among South Asians: A Silent Epidemic" 7517: 7506:
https://www.nccih.nih.gov/health/cardiovascular-disease
6552: 6439:
https://doi.org/10.1161/CIR.0000000000000510Circulation
5148: 4427: 2873: 1485:
Worldwide, dietary guidelines recommend a reduction in
1225:
can lead to these and other late side-effect symptoms.
1065:
or stroke twice as often as women during working life.
942:
has been studied for its short- and long-term exposure
10273: 6121: 5341: 4087:
Mukamal KJ, Chen CM, Rao SR, Breslow RA (March 2010).
3941: 3764: 2821: 2769: 2164: 2112: 1681:, may reduce risk factors for cardiovascular disease. 32:"Heart condition" redirects here. For other uses, see 10390: 9927: 9813: 9734:"Five Things Physicians and Patients Should Question" 9567: 9161: 8249: 7675: 7493:
https://medlineplus.gov/howtopreventheartdisease.html
7347: 6878: 6648: 6646: 6644: 5536:"NPS Prescribing Practice Review 53: Managing lipids" 4880: 4666: 4594: 4592: 4135: 4086: 3988: 3801: 3722:
Doll R, Peto R, Boreham J, Sutherland I (June 2004).
3328: 2987: 2924: 2467: 2213: 270:. CVDs constitute a class of diseases that includes: 12217: 11016: 7162: 6122:
Damen JA, Hooft L, Schuit E, Debray TP, Collins GS,
5938: 5846: 5680: 5070:"Occupational health and safety – chemical exposure" 4542: 4540: 3329:
Finegold JA, Asaria P, Francis DP (September 2013).
3109: 2379: 2275: 2070: 10630: 9881:"Exercise for people with high cardiovascular risk" 7255: 7012: 7010: 6074: 5183: 5028:"Occupational Exposures and Cardiovascular Disease" 4881:Cohen BE, Edmondson D, Kronish IM (November 2015). 4732: 3532: 3530: 3528: 3526: 2869: 2867: 749:
Calcified heart of an older woman with cardiomegaly
11122: 10126: 9483: 6641: 6454: 5186:"Understanding radiation-induced vascular disease" 4589: 3853:Nutrition, Metabolism, and Cardiovascular Diseases 3043: 2931:Arteriosclerosis, Thrombosis, and Vascular Biology 2822:Micha R, Michas G, Mozaffarian D (December 2012). 2817: 2815: 2327: 1006: 519:(coronary heart disease or ischemic heart disease) 10940: 10224: 9344: 6919: 4537: 4508: 4321: 4319: 4317: 3879: 3220: 1405:unclear whether or not dental care in those with 973: 659:– heart structure malformations existing at birth 14957: 10231:Circulation: Cardiovascular Quality and Outcomes 9718: 9684:US Preventive Services Task Force (March 2009). 9217: 9215: 7742: 7199: 7007: 6455:McTigue KM, Hess R, Ziouras J (September 2006). 5533: 5342:Belzile-Dugas E, Eisenberg MJ (September 2021). 5288: 5286: 4781: 4635: 4178: 3982: 3523: 3266: 2864: 2468:Spinks A, Glasziou PP, Del Mar CB (2021-12-09). 2380:McGill HC, McMahan CA, Gidding SS (March 2008). 812:almost as low a risk of death as never smokers. 604:. The structures most commonly involved are the 10472: 9316:"Statins in primary cardiovascular prevention?" 7348:Marshall IJ, Wolfe CD, McKevitt C (July 2012). 6303:Gan ZH, Cheong HC, Tu YK, Kuo PH (2021-11-05). 5097: 4080: 2812: 2276:Jackson CL, Redline S, Emmons KM (March 2015). 10473:Kwak SM, Myung SK, Lee YJ, Seo HG (May 2012). 8782: 8780: 8356: 8354: 6364: 6302: 5493:Therapeutic Advances in Cardiovascular Disease 5490: 5299:Therapeutic Advances in Cardiovascular Disease 5184:Weintraub NL, Jones WK, Manka D (March 2010). 4598: 4504: 4502: 4500: 4498: 4421: 4314: 3844: 3592:. World Heart Federation. 2012. 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Symptoms are dose-dependent and include 562:– diseases of the heart secondary to high 50: 10988:WHO fact sheet on cardiovascular diseases 10917: 10891: 10868: 10819: 10709: 10596: 10531: 10490: 10449: 10408: 10367: 10291: 10242: 10201: 10152: 10103: 10054: 10005: 9953: 9904: 9855: 9837: 9796: 9701: 9660: 9650: 9544: 9460: 9411: 9362: 9291: 9239: 9195: 9138: 9128: 8950: 8901: 8849: 8817: 8804: 8604: 8555: 8506: 8403: 8378: 8334: 8285: 8267: 8200: 8144: 8092: 8043: 8002: 7961: 7920: 7879: 7768: 7719: 7701: 7652: 7595: 7546: 7468: 7458: 7373: 7281: 7215:European Journal of Preventive Cardiology 7129: 7034: 6993:"Physical activity guidelines for adults" 6896: 6855: 6727: 6678: 6624: 6575: 6529: 6472: 6408: 6390: 6338: 6320: 6276: 6258: 6151: 6046: 6005: 5956: 5864: 5780: 5739: 5698: 5613: 5424: 5367: 5318: 5209: 5125: 5115: 4955: 4906: 4815: 4805: 4764: 4708: 4698: 4572: 4464: 4396: 4347: 4297: 4241: 4161: 4112: 4063: 4006: 3965: 3907: 3827: 3747: 3688: 3562: 3506: 3405: 3395: 3354: 3300: 3290: 3249: 3181: 3137: 3127: 3110:Kathiresan S, Srivastava D (March 2012). 3046:Current medical diagnosis & treatment 3010: 2942: 2918: 2901: 2891: 2847: 2787: 2696: 2611: 2560: 2550: 2501: 2397: 2370: 2353: 2301: 2271: 2269: 2249: 2231: 2190: 2138: 2108: 2106: 2104: 2026: 2024: 2022: 2020: 2018: 2016: 2014: 2012: 2010: 2008: 1988: 665:– heart muscles and valves damage due to 14712:Attention deficit hyperactivity disorder 14374: 10637:. 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A 2022 1624: 815: 14663: 14348: 13675: 12977: 12555:Hereditary hemorrhagic telangiectasia 12191: 11096: 10350:Lavigne PM, Karas RH (January 2013). 10329:10.1016/j.atherosclerosis.2009.12.023 9345:Downs JR, O'Malley PG (August 2015). 7984: 7206:Thompson DR, Ski CF (December 2013). 6360: 6358: 6298: 6296: 6236: 6234: 6070: 6068: 6066: 5762: 5527: 5018: 5016: 5014: 5012: 5010: 5008: 5006: 5004: 3590:"Cardiovascular disease risk factors" 3469: 3444:The Atlas of Heart Disease and Stroke 3159: 3157: 3074: 1953: 1903:to raise awareness about this issue. 1003:is also linked to an increased risk. 600:of the inner layer of the heart, the 13268:Infant respiratory distress syndrome 12560:Generalized essential telangiectasia 11483:Nonbacterial thrombotic endocarditis 9750:from the original on 3 November 2013 9726:American College of Chest Physicians 9614:from the original on 10 January 2015 9054: 8866: 7177:10.1001/archinte.1996.00440070065008 6247:Frontiers in Cardiovascular Medicine 5803: 4788:Eckel RH, Cornier MA (August 2014). 4547:Sun Q, Hong X, Wold LE (June 2010). 3774:Prevention of Cardiovascular Disease 1611: 1179:Radiation treatments (RT) for cancer 1173: 1148: 857:is associated with an increased risk 187:, excessive drug use, and excessive 14809:Epidemiology of Alzheimer's disease 9761: 8109: 7868:The New England Journal of Medicine 6556:International Journal of Cardiology 5898:Nature Clinical Practice. 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Philadelphia. 4887:American Journal of Hypertension 4831: 4724: 4662:from the original on 2016-05-06. 4491:from the original on 2016-05-01. 4205:from the original on 2016-05-07. 3537:Jani B, Rajkumar C (June 2006). 2789:10.1002/j.1875-9114.2011.01087.x 2660:from the original on 2017-09-08. 2642:. In Fuster V, Kelly BB (eds.). 2097:from the original on 2014-08-17. 934: 392:Cardiovascular diseases are the 34:Heart condition (disambiguation) 13661:Fetal Alcohol Spectrum Disorder 13611:Group B streptococcal infection 13179:Intrauterine growth restriction 11464:Subacute bacterial endocarditis 10741:from the original on 2015-05-18 10732: 10244:10.1161/CIRCOUTCOMES.117.004224 9241:10.1001/archinternmed.2012.2145 6365:Benatar JR, Stewart RA (2018). 6227:. NHS Direct. 28 November 2019. 6178:Current Atherosclerosis Reports 6168: 6115: 6022: 5973: 5932: 5889: 5840: 5797: 5715: 5674: 5630: 5589: 5554: 5484: 5441: 5142: 5091: 5038:from the original on 2017-06-14 4990:from the original on 2016-05-15 4972: 4923: 4874: 4839: 4372: 4129: 4031: 3795: 3715: 3705: 3664: 3630: 3600: 3434: 3422: 3371: 3214: 3103: 3068: 2828:Current Atherosclerosis Reports 2763: 2664: 2577: 2518: 2461: 2414: 1727: 1509:The benefits of recommending a 1428:Salt and cardiovascular disease 1187:radiation-induced heart disease 1007:Depression and traumatic stress 841:Salt and cardiovascular disease 772:Cardiovascular disease in women 683: 677:group A streptococcal infection 587:– abnormalities of heart rhythm 262:) is any disease involving the 13004:Conditions originating in the 12661:Hepatic veno-occlusive disease 11012:Interactive CV Risk Calculator 10694:10.1002/14651858.CD010315.pub5 10589:10.1002/14651858.CD005050.pub3 10492:10.1001/archinternmed.2012.262 10096:10.1002/14651858.CD011114.pub2 10047:10.1002/14651858.cd004017.pub2 9998:10.1002/14651858.CD010072.pub2 9897:10.1002/14651858.CD009387.pub2 9839:10.1002/14651858.CD001800.pub4 9789:10.1002/14651858.CD003610.pub4 9453:10.1002/14651858.CD009753.pub2 9284:10.1002/14651858.CD004816.pub5 9180:10.1002/14651858.CD011851.pub3 8894:10.1002/14651858.CD013496.pub2 8597:10.1002/14651858.CD009217.pub3 8499:10.1002/14651858.CD003177.pub5 8269:10.1002/14651858.CD011737.pub3 8004:10.1016/j.amjhyper.2006.10.006 7637:10.1002/14651858.CD009197.pub5 7588:10.1002/14651858.CD006887.pub4 7539:10.1002/14651858.CD011163.pub2 6949:10.1002/14651858.CD003041.pub3 6930:10.1002/14651858.CD003041.pub2 6522:10.1002/14651858.CD008274.pub4 4523:10.1016/j.thromres.2011.10.030 3820:10.1002/14651858.CD011737.pub3 2486:10.1002/14651858.CD000023.pub5 2346:10.1513/AnnalsATS.201609-662OC 2282:Annual Review of Public Health 2207: 1939: 1719:coronary artery bypass surgery 1052:those who are exposed to noise 974:Cardiovascular risk assessment 13: 1: 13353:Vitamin K deficiency bleeding 12473:Aneurysm of sinus of Valsalva 12327:Monckeberg's arteriosclerosis 11981:Pulseless electrical activity 11910:Multifocal atrial tachycardia 11784:Catecholaminergic polymorphic 10773:10.1016/s0140-6736(13)60598-x 10479:Archives of Internal Medicine 10410:10.1016/S0895-7061(02)02964-3 9946:10.1016/S0140-6736(12)61031-9 9498:10.1016/s0140-6736(14)60794-7 9228:Archives of Internal Medicine 9082:10.1016/s0140-6736(03)14739-3 8988:10.1016/S0140-6736(14)61212-5 8734:(This paper currently has an 8649:10.1016/S0140-6736(11)61174-4 7274:10.1016/j.amjcard.2014.04.022 7165:Archives of Internal Medicine 7122:10.1016/S0140-6736(21)00590-0 7036:10.1016/S0140-6736(15)01225-8 5652:10.1016/S0140-6736(98)12131-1 4648:. World Health Organization. 4340:10.1016/S0140-6736(12)61851-0 4191:. World Health Organization. 4154:10.1016/S0140-6736(18)31772-0 3003:10.1016/S0140-6736(04)17018-9 2439:10.1016/S0140-6736(16)30506-2 2183:10.1016/S0140-6736(16)31012-1 2131:10.1016/S0140-6736(14)61682-2 1932: 1684: 1633:is beneficial, the effect of 1537: 1309: 1113:and occupational exposure to 1014:posttraumatic stress disorder 989:ankle–brachial pressure index 704:), raised blood cholesterol ( 422:Disability-adjusted life year 14580:Obstetric labor complication 13512:Periventricular leukomalacia 13330:Persistent fetal circulation 13278:Meconium aspiration syndrome 12778:Chronic venous insufficiency 12403:Aortoiliac occlusive disease 11003:Slides, photos, descriptions 10737:. Indian Heart Association. 9326:(195): 183. July–August 2018 9130:10.1161/HYP.0000000000000003 9064:Turnbull F (November 2003). 9032:10.1097/HJH.0b013e32834000be 8548:10.1001/jamacardio.2017.5205 8380:10.1161/CIR.0000000000000510 8209:Journal of Internal Medicine 7837:10.1016/j.amjmed.2011.04.024 7703:10.1016/j.envint.2021.106595 7319:10.1016/j.amjmed.2014.04.004 6568:10.1016/j.ijcard.2014.02.026 6392:10.1371/journal.pone.0209086 6048:10.1373/clinchem.2012.182287 5741:10.1161/CIR.0000000000000025 5575:10.1016/j.ijcard.2006.11.003 5163:10.1016/j.ijrobp.2007.05.034 4700:10.1371/journal.pone.0106455 4290:10.1161/CIR.0000000000000444 3865:10.1016/j.numecd.2008.02.005 3543:Postgraduate Medical Journal 3539:"Ageing and vascular ageing" 3347:10.1016/j.ijcard.2012.10.046 2944:10.1161/ATV.0000000000000153 2591:Health Technology Assessment 2552:10.1371/journal.pone.0081970 1981:10.1161/cir.0b013e31828124ad 1520:left ventricular hypertrophy 1276:myocardial perfusion imaging 1261: 590:Inflammatory heart diseases 556:– diseases of cardiac muscle 7: 14322:superior vena cava syndrome 13421:Intraventricular hemorrhage 12793:Inferior vena cava syndrome 12788:Superior vena cava syndrome 12515:Vertebral artery dissection 12505:Intracranial berry aneurysm 10280:Annals of Internal Medicine 9690:Annals of Internal Medicine 9351:Annals of Internal Medicine 8943:10.1136/bmj.39548.738368.BE 8842:10.1136/bmj.39147.604896.55 8413:Annals of Internal Medicine 7881:10.1056/NEJM200101043440101 5806:Annals of Internal Medicine 5769:Annals of Internal Medicine 3740:10.1136/bmj.38142.554479.AE 2880:World Journal of Cardiology 1906: 1451:Evidence suggests that the 731: 523:Peripheral arterial disease 10: 14987: 14575:Complications of pregnancy 13426:Germinal matrix hemorrhage 13416:Velamentous cord insertion 13307:Bronchopulmonary dysplasia 12894:Hypertensive heart disease 12545:Arteriovenous malformation 12520:Familial aortic dissection 11925:Wandering atrial pacemaker 11472:non-infective endocarditis 11413:Endocardial fibroelastosis 10943:Nature Reviews. Cardiology 10898:Nature Reviews. Cardiology 10849:Nature Reviews. Cardiology 10533:10.1016/j.jacc.2022.09.048 10369:10.1016/j.jacc.2012.10.030 9652:10.1016/j.jacc.2019.03.010 7963:10.2337/diacare.28.12.2823 6971:"Chapter 4: Active Adults" 6126:, et al. (May 2016). 6029:Saenger AK (August 2012). 5615:10.1016/j.jacc.2003.08.050 5202:10.1016/j.jacc.2009.11.053 4430:Nature Reviews. Cardiology 4105:10.1016/j.jacc.2009.10.056 3900:10.1016/j.jada.2009.12.024 3650:10.3310/nihrevidence_60660 3183:10.1016/j.jacc.2020.12.071 3129:10.1016/j.cell.2012.03.001 1949:. Mayo Clinic. 2022-08-25. 1910: 1562:, while they may increase 1417: 1023: 995:, white blood cell count, 926:Socioeconomic disadvantage 904:sleep-disordered breathing 866: 862: 834: 819: 806: 769: 560:Hypertensive heart disease 288:hypertensive heart disease 153:hypertensive heart disease 31: 14966:Aging-associated diseases 14699: 14639: 14621:Connective tissue disease 14606: 14593: 14570: 14542: 14524: 14511: 14493: 14470: 14457: 14444: 14416: 14398: 14380: 14291: 14235:radial artery sufficiency 14191: 14182: 14130: 14097: 14058: 14015: 14006: 13967: 13920: 13870: 13743: 13713: 13626: 13561: 13520: 13497: 13469: 13456:Necrotizing enterocolitis 13441: 13338: 13315: 13253: 13246: 13187: 13165:Large for gestational age 13161:Small for gestational age 13153: 13117: 13085: 13059: 13027: 13016: 12949: 12919:Renovascular hypertension 12884: 12875: 12862:Hepatic artery thrombosis 12810: 12770: 12725: 12629: 12611: 12602: 12570: 12530: 12510:Carotid artery dissection 12463:Abdominal aortic aneurysm 12435: 12395: 12372: 12313:Intermittent claudication 12283: 12276:Peripheral artery disease 12274: 12244: 12226: 12142: 12085: 12003:hexaxial reference system 11994: 11961: 11948:Jervell and Lange-Nielsen 11933: 11891: 11850: 11827: 11801: 11769: 11727: 11708: 11607: 11593: 11493: 11478:Libman–Sacks endocarditis 11447: 11433: 11349: 11298: 11291: 11228: 11183: 11140: 11131: 11020: 10955:10.1038/nrcardio.2016.209 10910:10.1038/nrcardio.2016.216 10861:10.1038/nrcardio.2016.185 10802:Alberti FB (2013-05-01). 10145:10.1016/j.cca.2011.04.038 9730:American Thoracic Society 9586:10.1016/j.ahj.2011.04.006 9546:10.1007/s00125-009-1470-0 8045:10.1017/S0007114516001938 7794:American Family Physician 7682:Environment International 6225:"Heart Attackβ€”Prevention" 6190:10.1007/s11883-009-0072-0 5992:(Supplement 5): S213-56. 5763:Moyer VA (October 2012). 4948:10.1016/j.ahj.2013.07.031 4860:10.1016/j.cca.2016.07.020 4442:10.1038/nrcardio.2009.163 2840:10.1007/s11883-012-0282-8 2728:World Health Organization 1439:A 2021 review found that 1413: 1215:peripheral artery disease 1056:Specifically the risk of 1035:Non-chemical risk factors 785:World Health Organization 320:peripheral artery disease 249:17.9 million / 32% (2015) 245: 225: 206: 195: 170: 136: 128: 118: 94: 82: 58: 49: 44: 14883:Motor vehicle collisions 14611:Musculoskeletal disorder 14534:Gastrointestinal disease 13845:Pericardial friction rub 12904:Hypertensive nephropathy 12717:Post-thrombotic syndrome 12698:Paget–Schroetter disease 12490:Coronary artery aneurysm 12468:Thoracic aortic aneurysm 11883:Ventricular fibrillation 11154:Coronary artery aneurysm 9072:(Submitted manuscript). 7227:10.1177/2047487313494031 6260:10.3389/fcvm.2021.756810 5505:10.1177/1753944709354305 5311:10.1177/1753944717729141 4807:10.1186/1741-7015-12-115 3555:10.1136/pgmj.2005.036053 3508:10.1161/01.cir.99.9.1165 3089:10.1161/01.CIR.96.9.3248 1897:Indian Heart Association 1617:cardiovascular disease. 1571:Anti-diabetic medication 902:Sleep disorders such as 893: 657:Congenital heart disease 640:Eosinophilic myocarditis 412: 338:. This may be caused by 304:congenital heart disease 272:coronary artery diseases 141:Coronary artery diseases 14971:Cardiovascular diseases 14281:Nicoladoni–Branham sign 13945:Jugular venous pressure 13807:Pulmonary insufficiency 13618:Neonatal conjunctivitis 13109:Single umbilical artery 13099:Umbilical cord prolapse 13046:Placental insufficiency 13019:complicating pregnancy, 12959:Orthostatic hypotension 12941:White coat hypertension 12418:Fibromuscular dysplasia 12382:Carotid artery stenosis 12160:Diastolic heart failure 12134:Athletic heart syndrome 12095:Ventricular hypertrophy 11829:Pre-excitation syndrome 11683:Left posterior fascicle 11208:Acute coronary syndrome 11148:Coronary artery disease 9741:: an initiative of the 9320:Prescrire International 9020:Journal of Hypertension 8744:10.1042/CS-20070193_EOC 8137:10.1093/advances/nmz024 7985:Logan AG (March 2007). 7400:Journal of Hypertension 6898:10.1001/jama.2015.15629 5998:10.1542/peds.2009-2107C 5360:10.1161/JAHA.121.021686 4613:10.1136/hrt.2010.214858 3967:10.3945/ajcn.113.081521 1575:relative risk reduction 1296:coronary artery calcium 1207:coronary artery disease 1139:pulmonary heart disease 830: 700:), raised blood sugar ( 663:Rheumatic heart disease 579:Pulmonary heart disease 529:Cerebrovascular disease 517:Coronary artery disease 366:consumption, and poor 362:, poor diet, excessive 292:rheumatic heart disease 157:rheumatic heart disease 14732:Cardiovascular disease 14552:Female genital disease 14529:Maxillofacial disorder 14498:Cardiovascular disease 14170:Gallavardin phenomenon 14008:Cardiovascular disease 13594:ureaplasma urealyticum 13302:Wilson–Mikity syndrome 13226:Brachial plexus injury 12931:Pulmonary hypertension 12914:Secondary hypertension 12909:Essential hypertension 12899:Hypertensive emergency 12740:Portacaval anastomosis 12676:Portal vein thrombosis 12318:Critical limb ischemia 12219:Cardiovascular disease 11678:Left anterior fascicle 11458:infective endocarditis 11243:Hibernating myocardium 11124:Cardiovascular disease 9574:American Heart Journal 8131:(Suppl_4): S332–S339. 6809:10.1542/peds.2006-0970 6433:Penny M. Kris-Etherton 5958:10.1001/jama.2018.8359 5700:10.1001/jama.2018.6848 5104:Seminars in Hematology 5100:"Clonal hematopoiesis" 4936:American Heart Journal 4398:10.1053/euhj.1999.1990 4385:European Heart Journal 4234:10.1542/peds.2017-4085 2730:. 2009. Archived from 1901:World Heart Federation 1887: 1799: 1280:cardiac stress testing 1239: 1203:valvular heart disease 1117:. Working with the 765: 750: 740: 672:Streptococcus pyogenes 652:Valvular heart disease 620:– inflammation of the 505: 398:Deaths, at a given age 394:leading cause of death 360:high blood cholesterol 324:thromboembolic disease 308:valvular heart disease 256:Cardiovascular disease 45:Cardiovascular disease 14910:Risky sexual behavior 14694:of medical conditions 14475:Neurological disorder 14275:arteriovenous fistula 14089:Bracht–Wachter bodies 13542:Congenital hypertonia 13433:Anemia of prematurity 13141:Shoulder presentation 12936:Systolic hypertension 12681:Renal vein thrombosis 12540:Arteriovenous fistula 12532:Vascular malformation 12500:Intracranial aneurysm 12387:Renal artery stenosis 11842:Wolff–Parkinson–White 11802:Premature contraction 11700:Adams–Stokes syndrome 11403:Loeffler endocarditis 11213:Myocardial infarction 10804:"John Hunter's Heart" 8793:Public Health Reviews 8767:expression of concern 8761:|...}} 8759:expression of concern 8736:expression of concern 8125:Advances in Nutrition 6943:(Retracted, see 5254:10.1148/rg.2019180061 2893:10.4330/wjc.v9.i8.652 1899:are working with the 1805: 1735: 1695:influenza vaccination 1446:observational studies 1256:hypercholesterolaemia 1236: 1069:Chemical risk factors 1020:Occupational exposure 1001:High blood phosphorus 867:Further information: 835:Further information: 820:Further information: 748: 539:Renal artery stenosis 420: 113:loss of consciousness 14900:Periodontal diseases 14616:Soft tissue disorder 14562:Male genital disease 14375:Major Disease groups 14112:Pericardial effusion 14017:Aortic insufficiency 13830:Mitral insufficiency 13812:Graham Steell murmur 13547:Congenital hypotonia 13461:Meconium peritonitis 13263:Intrauterine hypoxia 13219:Subgaleal hemorrhage 12850:Paradoxical embolism 12845:Cholesterol embolism 12671:May–Thurner syndrome 12666:Budd–Chiari syndrome 12649:Deep vein thrombosis 12644:primarily lower limb 12423:Raynaud's phenomenon 12009:Right axis deviation 11971:Sudden cardiac death 11329:Pericardial effusion 11272:Ventricular aneurysm 7922:10.1093/ajcn/74.1.80 7116:(10285): 1625–1636. 6474:10.1038/oby.2006.171 5910:10.1038/ncpneuro0324 5866:10.1056/NEJMoa055373 5026:(SBU) (2015-08-26). 4148:(10183): 1831–1842. 2177:(10053): 1459–1544. 1715:coronary angioplasty 1532:intermittent fasting 1526:Intermittent fasting 1491:polyunsaturated fats 1288:Ankle-brachial index 1168:clonal hematopoiesis 585:Cardiac dysrhythmias 14644:Congenital disorder 14585:Postpartum disorder 14516:Respiratory disease 14449:Hematologic disease 14045:Austin Flint murmur 13824:Carey Coombs murmur 13656:Neonatal withdrawal 13639:Perinatal mortality 13489:Sclerema neonatorum 13345:hematologic disease 12926:Benign hypertension 12014:Left axis deviation 11871:Atrial fibrillation 11866:Ventricular flutter 11789:Torsades de pointes 11663:Bundle branch block 11622:Sick sinus syndrome 11408:Cardiac amyloidosis 11393:Tachycardia-induced 11248:Myocardial stunning 11196:Prinzmetal's angina 11165:Coronary thrombosis 10139:(17–18): 1493–514. 7694:2021EnInt.15406595P 6383:2018PLoSO..1309086B 5409:2013NatMa..12..576B 4691:2014PLoSO...9j6455V 4511:Thrombosis Research 3397:10.1155/2015/912047 2543:2013PLoSO...881970S 1924:biomedical research 1675:dietary supplements 1659:torsades de pointes 1625:Dietary supplements 1504:omega-3 fatty acids 1386:myocardial ischemia 1382:psychosocial stress 1199:myocardial fibrosis 1111:metalworking fluids 822:Sedentary lifestyle 816:Physical inactivity 502: More than 770 340:high blood pressure 212:high blood pressure 105:shortness of breath 14866:Metabolic syndrome 14431:Metabolic disorder 14316:Trendelenburg test 14249:pseudohypertension 14227:Right heart strain 14221:pulmonary embolism 13836:Presystolic murmur 13707:circulatory system 13703:Signs and symptoms 13589:mycoplasma hominis 13574:Neonatal infection 13530:Gray baby syndrome 13507:Perinatal asphyxia 13397:Hyperbilirubinemia 13174:Postterm pregnancy 13021:labour or delivery 12840:Pulmonary embolism 12750:Esophageal varices 12688:upper limb / torso 12332:Arteriolosclerosis 12117:Atrial enlargement 11915:Pacemaker syndrome 11837:Lown–Ganong–Levine 11759:Junctional ectopic 11754:AV nodal reentrant 11260:Myocardial rupture 11170:Coronary vasospasm 9732:(September 2013), 8806:10.1007/BF03391649 8713:10.1042/CS20070193 7029:(10022): 957–967. 6322:10.3390/nu13113952 6035:Clinical Chemistry 4899:10.1093/ajh/hpv047 2233:10.3390/nu13124305 1888: 1800: 1667:omega-3 fatty acid 1476:metabolic syndrome 1453:Mediterranean diet 1390:Takotsubo syndrome 1324:Mediterranean diet 1240: 966:is also linked to 940:Particulate matter 914:or other chronic 751: 506: 436: Less than 70 14953: 14952: 14940:Teenage pregnancy 14826:Domestic violence 14821:Diabetes mellitus 14657: 14656: 14503:Lymphatic disease 14421:Endocrine disease 14390:Parasitic disease 14342: 14341: 14338: 14337: 14301:Friedreich's sign 14208:Cardarelli's sign 14178: 14177: 14108:Cardiac tamponade 13900:Pulsus bisferiens 13790:Functional murmur 13669: 13668: 13557: 13556: 13407:Neonatal jaundice 13325:Pneumopericardium 13295:Pneumomediastinum 13236:Klumpke paralysis 13214:Caput succedaneum 13149: 13148: 13017:Maternal factors 12971: 12970: 12967: 12966: 12811:Arteries or veins 12806: 12805: 12631:Venous thrombosis 12598: 12597: 12580:Cherry hemangioma 12480:Aortic dissection 12431: 12430: 12266:Buerger's disease 12185: 12184: 12177:Obstructive shock 12081: 12080: 12028:Short QT syndrome 11995:Other / ungrouped 11986:Sinoatrial arrest 11901:Ectopic pacemaker 11797: 11796: 11617:Sinus bradycardia 11589: 11588: 11585: 11584: 11334:Cardiac tamponade 11287: 11286: 11277:Dressler syndrome 11175:Myocardial bridge 11090: 11089: 10767:(9873): 1211–22. 10644:978-0-323-55593-7 10526:(24): 2269–2285. 9645:(10): e177–e232. 9492:(9933): 2008–17. 9404:10.1136/bmj.g4379 9076:(9395): 1527–35. 8982:(9943): 591–598. 8327:10.1136/bmj.h3978 8181:978-92-5-106733-8 8085:10.1136/bmj.e8707 7761:10.1136/bmj.g4490 7366:10.1136/bmj.e3953 7063:medicalxpress.com 6891:(19): 2008–2024. 6765:10.1586/erc.09.22 6720:10.1136/bmj.g4164 6144:10.1136/bmj.i2416 6086:978-1-4557-5133-4 5693:(22): 2308–2314. 5196:(12): 1237–1239. 4655:978-92-4-154717-8 4484:978-92-4-156370-3 4284:(18): e367–e386. 4198:978-92-4-156415-1 3784:978-92-4-154726-0 3462:978-92-4-156276-8 3236:(10): 1121–1130. 3176:(20): 2517–2530. 3061:978-0-07-176372-1 3042:McPhee S (2012). 2756:978-0-309-14774-3 2653:978-0-309-14774-3 2433:(10046): 761–75. 2087:978-92-4-156437-3 1796: 5,272–10233 1790: 3,204–5,271 1784: 2,625–3,203 1778: 2,099–2,624 1772: 1,803–2,098 1766: 1,450–1,802 1760: 1,295–1,449 1754: 1,149–1,294 1661:who present with 1637:supplementation ( 1612:Physical activity 1499:trans fatty acids 1461:cholesterol level 1441:plant-based diets 1248:diabetes mellitus 1174:Radiation therapy 1149:Somatic mutations 1103:carbon disulphide 726:coronary arteries 702:diabetes mellitus 634:white blood cells 510:vascular diseases 348:diabetes mellitus 328:venous thrombosis 253: 252: 216:high blood lipids 183:, excess weight, 181:high blood lipids 39:Medical condition 16:(Redirected from 14978: 14871:Mental disorders 14684: 14677: 14670: 14661: 14660: 14547:Urologic disease 14369: 14362: 14355: 14346: 14345: 14328:Pemberton's sign 14189: 14188: 14184:Vascular disease 14030:De Musset's sign 14025:Collapsing pulse 14013: 14012: 13912:Pulsus alternans 13905:Pulsus bigeminus 13890:Pulsus paradoxus 13705:relating to the 13696: 13689: 13682: 13673: 13672: 13649:Infant mortality 13484:Erythema toxicum 13476:thermoregulation 13443:Gastrointestinal 13251: 13250: 13247:Affected systems 13124: 13092: 13077:Chorioamnionitis 13070: 13041:Placenta praevia 13034: 13025: 13024: 12998: 12991: 12984: 12975: 12974: 12882: 12881: 12693:Mondor's disease 12636:Thrombophlebitis 12609: 12608: 12285:Arteriosclerosis 12281: 12280: 12242: 12241: 12212: 12205: 12198: 12189: 12188: 12150:Cardiac fibrosis 12042:T wave alternans 11935:Long QT syndrome 11729:Supraventricular 11725: 11724: 11658:Intraventricular 11605: 11604: 11445: 11444: 11296: 11295: 11141:Coronary disease 11138: 11137: 11117: 11110: 11103: 11094: 11093: 11018: 11017: 10975: 10974: 10938: 10932: 10931: 10921: 10889: 10883: 10882: 10872: 10840: 10834: 10833: 10823: 10799: 10793: 10792: 10756: 10750: 10749: 10747: 10746: 10730: 10724: 10723: 10713: 10688:(11): CD010315. 10673: 10667: 10666: 10655: 10649: 10648: 10628: 10619: 10618: 10600: 10568: 10562: 10561: 10535: 10511: 10505: 10504: 10494: 10470: 10464: 10463: 10453: 10444:(10): e385-484. 10429: 10423: 10422: 10412: 10388: 10382: 10381: 10371: 10347: 10341: 10340: 10312: 10306: 10305: 10295: 10271: 10265: 10264: 10246: 10222: 10216: 10215: 10205: 10173: 10167: 10166: 10156: 10124: 10118: 10117: 10107: 10075: 10069: 10068: 10058: 10026: 10020: 10019: 10009: 9983: 9974: 9968: 9967: 9957: 9940:(9838): 219–29. 9925: 9919: 9918: 9908: 9876: 9870: 9869: 9859: 9841: 9832:(11): CD001800. 9817: 9811: 9810: 9800: 9768: 9759: 9758: 9757: 9755: 9722: 9716: 9715: 9705: 9681: 9675: 9674: 9664: 9654: 9630: 9624: 9623: 9621: 9619: 9604: 9598: 9597: 9580:(1): 115–24.e2. 9565: 9559: 9558: 9548: 9524: 9518: 9517: 9481: 9475: 9474: 9464: 9432: 9426: 9425: 9415: 9383: 9377: 9376: 9366: 9364:10.7326/m15-0840 9342: 9336: 9335: 9333: 9331: 9312: 9306: 9305: 9295: 9269: 9260: 9254: 9253: 9243: 9219: 9210: 9209: 9199: 9159: 9153: 9152: 9142: 9132: 9108: 9102: 9101: 9061: 9052: 9051: 9014: 9008: 9007: 8971: 8965: 8964: 8954: 8937:(7653): 1121–3. 8922: 8916: 8915: 8905: 8873: 8864: 8863: 8853: 8821: 8815: 8814: 8808: 8784: 8775: 8774: 8772: 8770: 8762: 8732: 8701:Clinical Science 8698: 8689: 8683: 8682: 8680: 8679: 8673: 8667:. Archived from 8634: 8625: 8619: 8618: 8608: 8591:(12): CD009217. 8576: 8570: 8569: 8559: 8527: 8521: 8520: 8510: 8478: 8472: 8471: 8456:Federal Register 8451: 8445: 8444: 8425:10.7326/M13-1788 8407: 8401: 8400: 8382: 8358: 8349: 8348: 8338: 8321:(h3978): h3978. 8306: 8300: 8299: 8289: 8271: 8247: 8241: 8240: 8204: 8198: 8197: 8192:. Archived from 8165: 8159: 8158: 8148: 8116: 8107: 8106: 8096: 8064: 8058: 8057: 8047: 8023: 8017: 8016: 8006: 7982: 7976: 7975: 7965: 7941: 7935: 7934: 7924: 7900: 7894: 7893: 7883: 7859: 7853: 7852: 7831:(9): 841–51.e2. 7816: 7810: 7809: 7789: 7783: 7782: 7772: 7740: 7734: 7733: 7723: 7705: 7673: 7667: 7666: 7656: 7631:(10): CD009197. 7616: 7610: 7609: 7599: 7567: 7561: 7560: 7550: 7524: 7515: 7509: 7502: 7496: 7489: 7483: 7482: 7472: 7462: 7438: 7432: 7431: 7394: 7388: 7387: 7377: 7345: 7339: 7338: 7302: 7296: 7295: 7285: 7253: 7247: 7246: 7212: 7203: 7197: 7196: 7160: 7154: 7149:Available under 7148: 7143: 7133: 7101: 7095: 7094: 7092: 7090: 7080: 7074: 7073: 7071: 7069: 7055: 7049: 7048: 7038: 7014: 7005: 7004: 6989: 6983: 6982: 6967: 6961: 6960: 6941: 6917: 6911: 6910: 6900: 6876: 6870: 6869: 6859: 6835: 6829: 6828: 6791: 6785: 6784: 6748: 6742: 6741: 6731: 6699: 6693: 6692: 6682: 6650: 6639: 6638: 6628: 6617:10.1136/bmj.d671 6596: 6590: 6589: 6579: 6550: 6544: 6543: 6533: 6501: 6495: 6494: 6476: 6452: 6446: 6441:2017;136:e1–e23, 6429: 6423: 6422: 6412: 6394: 6377:(12): e0209086. 6362: 6353: 6352: 6342: 6324: 6300: 6291: 6290: 6280: 6262: 6238: 6229: 6228: 6221: 6210: 6209: 6172: 6166: 6165: 6155: 6119: 6113: 6112: 6106: 6098: 6072: 6061: 6060: 6050: 6026: 6020: 6019: 6009: 5977: 5971: 5970: 5960: 5936: 5930: 5929: 5893: 5887: 5886: 5868: 5844: 5838: 5837: 5818:10.7326/M14-1225 5801: 5795: 5794: 5784: 5760: 5754: 5753: 5743: 5719: 5713: 5712: 5702: 5678: 5672: 5671: 5646:(9179): 617–21. 5634: 5628: 5627: 5617: 5593: 5587: 5586: 5558: 5552: 5551: 5549: 5547: 5542:on 19 March 2011 5538:. Archived from 5531: 5525: 5524: 5488: 5482: 5481: 5445: 5439: 5438: 5428: 5417:10.1038/nmat3627 5397:Nature Materials 5388: 5382: 5381: 5371: 5348:J Am Heart Assoc 5339: 5333: 5332: 5322: 5290: 5281: 5280: 5278: 5276: 5233: 5224: 5223: 5213: 5181: 5175: 5174: 5146: 5140: 5139: 5129: 5119: 5095: 5089: 5088: 5086: 5085: 5076:. Archived from 5062: 5047: 5046: 5044: 5043: 5020: 4999: 4998: 4996: 4995: 4976: 4970: 4969: 4959: 4927: 4921: 4920: 4910: 4893:(11): 1295–302. 4878: 4872: 4871: 4843: 4837: 4836: 4835: 4829: 4819: 4809: 4785: 4779: 4778: 4768: 4736: 4730: 4729: 4728: 4722: 4712: 4702: 4670: 4664: 4663: 4639: 4633: 4632: 4596: 4587: 4586: 4576: 4544: 4535: 4534: 4506: 4493: 4492: 4468: 4462: 4461: 4425: 4419: 4418: 4400: 4376: 4370: 4369: 4351: 4334:(9866): 585–97. 4323: 4312: 4311: 4301: 4269: 4263: 4262: 4260: 4258: 4245: 4228:(1): e20174085. 4213: 4207: 4206: 4182: 4176: 4175: 4165: 4133: 4127: 4126: 4116: 4084: 4078: 4077: 4067: 4056:10.1136/bmj.j909 4035: 4029: 4028: 4010: 3986: 3980: 3979: 3969: 3945: 3939: 3938: 3931: 3922: 3921: 3911: 3883: 3877: 3876: 3848: 3842: 3841: 3831: 3799: 3793: 3792: 3768: 3762: 3761: 3751: 3719: 3713: 3709: 3703: 3702: 3692: 3683:(7): 1427–1438. 3668: 3662: 3661: 3634: 3628: 3627: 3625: 3623: 3614:. May 22, 2014. 3604: 3598: 3597: 3586: 3577: 3576: 3566: 3534: 3521: 3520: 3510: 3486: 3467: 3466: 3438: 3432: 3426: 3420: 3419: 3409: 3399: 3375: 3369: 3368: 3358: 3326: 3315: 3314: 3304: 3294: 3270: 3264: 3263: 3253: 3227: 3218: 3212: 3211: 3185: 3161: 3152: 3151: 3141: 3131: 3107: 3101: 3100: 3072: 3066: 3065: 3049: 3039: 3033: 3032: 3014: 2997:(9438): 937–52. 2985: 2979: 2978: 2972: 2964: 2946: 2937:(6): e168–e185. 2922: 2916: 2915: 2905: 2895: 2871: 2862: 2861: 2851: 2819: 2810: 2809: 2791: 2767: 2761: 2760: 2742: 2736: 2735: 2720: 2711: 2710: 2700: 2668: 2662: 2661: 2635: 2626: 2625: 2615: 2604:10.3310/hta17430 2581: 2575: 2574: 2564: 2554: 2522: 2516: 2515: 2505: 2480:(12): CD000023. 2465: 2459: 2458: 2418: 2412: 2411: 2401: 2377: 2368: 2367: 2357: 2325: 2316: 2315: 2305: 2273: 2264: 2263: 2253: 2235: 2211: 2205: 2204: 2194: 2162: 2153: 2152: 2142: 2125:(9963): 117–71. 2110: 2099: 2098: 2096: 2079: 2068: 2003: 2002: 1992: 1960: 1951: 1950: 1943: 1917:Vessel-on-a-chip 1883: 1877: 1871: 1865: 1859: 1853: 1847: 1841: 1835: 1829: 1823: 1817: 1811: 1795: 1789: 1783: 1777: 1771: 1765: 1759: 1753: 1747: 1741: 1673:found that some 1663:long QT syndrome 1657:associated with 1420:Lipid hypothesis 1369:Stopping smoking 1336:plant-based diet 1272:echocardiography 1223:oxidative stress 1211:heart arrhythmia 888:gluten-free diet 845:Lipid hypothesis 501: 495: 489: 483: 477: 471: 465: 459: 453: 447: 441: 435: 429: 402:developing world 316:aortic aneurysms 54: 42: 41: 21: 14986: 14985: 14981: 14980: 14979: 14977: 14976: 14975: 14956: 14955: 14954: 14949: 14695: 14688: 14658: 14653: 14635: 14602: 14589: 14566: 14538: 14520: 14507: 14489: 14466: 14462:Mental disorder 14453: 14440: 14436:Immune disorder 14412: 14394: 14376: 14373: 14343: 14334: 14311:Kussmaul's sign 14287: 14202:aortic aneurysm 14174: 14146:Anitschkow cell 14139:rheumatic fever 14126: 14093: 14054: 14035:Duroziez's sign 14002: 13963: 13916: 13866: 13739: 13709: 13700: 13670: 13665: 13622: 13606:Neonatal sepsis 13553: 13522:Musculoskeletal 13516: 13493: 13474: 13465: 13437: 13392:Hydrops fetalis 13343: 13334: 13311: 13284:Pleural disease 13242: 13204:Cephalohematoma 13183: 13145: 13118: 13113: 13086: 13081: 13060: 13055: 13028: 13020: 13018: 13012: 13002: 12972: 12963: 12945: 12871: 12828:Microangiopathy 12823:Macroangiopathy 12802: 12766: 12735:Gastric varices 12721: 12634: 12625: 12594: 12566: 12526: 12458:Aortic aneurysm 12444: 12427: 12413:Erythromelalgia 12391: 12368: 12293:Atherosclerosis 12270: 12234: 12222: 12216: 12186: 12181: 12172:Rheumatic fever 12138: 12077: 11990: 11957: 11929: 11887: 11846: 11823: 11793: 11765: 11712: 11704: 11598: 11581: 11489: 11438: 11429: 11345: 11339:Hemopericardium 11283: 11224: 11218:Unstable angina 11191:Angina pectoris 11184:Active ischemia 11179: 11127: 11121: 11091: 11086: 11085: 11029: 11007:Risk calculator 10984: 10979: 10978: 10939: 10935: 10890: 10886: 10841: 10837: 10800: 10796: 10757: 10753: 10744: 10742: 10731: 10727: 10674: 10670: 10657: 10656: 10652: 10645: 10629: 10622: 10583:(5): CD005050. 10569: 10565: 10512: 10508: 10471: 10467: 10430: 10426: 10389: 10385: 10348: 10344: 10317:Atherosclerosis 10313: 10309: 10272: 10268: 10223: 10219: 10194:10.1136/bmj.f10 10174: 10170: 10125: 10121: 10090:(3): CD011114. 10076: 10072: 10041:(1): CD004017. 10027: 10023: 9992:(5): CD010072. 9981: 9975: 9971: 9926: 9922: 9891:(8): CD009387. 9877: 9873: 9818: 9814: 9783:(5): CD003610. 9769: 9762: 9753: 9751: 9743:ABIM Foundation 9739:Choosing Wisely 9723: 9719: 9682: 9678: 9631: 9627: 9617: 9615: 9606: 9605: 9601: 9566: 9562: 9539:(11): 2288–98. 9525: 9521: 9482: 9478: 9447:(3): CD009753. 9433: 9429: 9384: 9380: 9343: 9339: 9329: 9327: 9314: 9313: 9309: 9278:(1): CD004816. 9267: 9261: 9257: 9220: 9213: 9174:(3): CD011851. 9160: 9156: 9109: 9105: 9062: 9055: 9015: 9011: 8972: 8968: 8923: 8919: 8888:(3): CD013496. 8874: 8867: 8836:(7599): 885–8. 8822: 8818: 8785: 8778: 8764: 8756: 8754: 8733: 8696: 8690: 8686: 8677: 8675: 8671: 8643:(9789): 380–2. 8632: 8626: 8622: 8577: 8573: 8536:JAMA Cardiology 8528: 8524: 8493:(3): CD003177. 8479: 8475: 8462:(98): 23358–9. 8452: 8448: 8408: 8404: 8359: 8352: 8307: 8303: 8262:(8): CD011737. 8248: 8244: 8205: 8201: 8182: 8166: 8162: 8117: 8110: 8065: 8061: 8024: 8020: 7983: 7979: 7956:(12): 2823–31. 7942: 7938: 7901: 7897: 7860: 7856: 7817: 7813: 7790: 7786: 7741: 7737: 7674: 7670: 7617: 7613: 7582:(6): CD006887. 7568: 7564: 7533:(8): CD011163. 7522: 7516: 7512: 7503: 7499: 7490: 7486: 7439: 7435: 7395: 7391: 7346: 7342: 7303: 7299: 7254: 7250: 7210: 7204: 7200: 7161: 7157: 7102: 7098: 7088: 7086: 7082: 7081: 7077: 7067: 7065: 7057: 7056: 7052: 7015: 7008: 6991: 6990: 6986: 6969: 6968: 6964: 6942: 6924:(1): CD003041. 6918: 6914: 6877: 6873: 6850:(24): 3786–94. 6836: 6832: 6792: 6788: 6749: 6745: 6700: 6696: 6651: 6642: 6597: 6593: 6551: 6547: 6516:(2): CD008274. 6502: 6498: 6453: 6449: 6430: 6426: 6363: 6356: 6301: 6294: 6239: 6232: 6223: 6222: 6213: 6173: 6169: 6120: 6116: 6100: 6099: 6087: 6073: 6064: 6027: 6023: 5978: 5974: 5937: 5933: 5894: 5890: 5845: 5841: 5802: 5798: 5761: 5757: 5734:(15): 1303–34. 5720: 5716: 5679: 5675: 5635: 5631: 5594: 5590: 5559: 5555: 5545: 5543: 5532: 5528: 5489: 5485: 5446: 5442: 5389: 5385: 5354:(18): e021686. 5340: 5336: 5305:(11): 297–317. 5291: 5284: 5274: 5272: 5234: 5227: 5182: 5178: 5147: 5143: 5096: 5092: 5083: 5081: 5063: 5050: 5041: 5039: 5021: 5002: 4993: 4991: 4978: 4977: 4973: 4928: 4924: 4879: 4875: 4844: 4840: 4830: 4786: 4782: 4751:(17): 2408–16. 4737: 4733: 4723: 4685:(10): e106455. 4671: 4667: 4656: 4640: 4636: 4597: 4590: 4559:(25): 2755–65. 4545: 4538: 4507: 4496: 4485: 4469: 4465: 4426: 4422: 4391:(14): 1141–51. 4377: 4373: 4324: 4315: 4270: 4266: 4256: 4254: 4214: 4210: 4199: 4183: 4179: 4134: 4130: 4099:(13): 1328–35. 4085: 4081: 4036: 4032: 3987: 3983: 3946: 3942: 3933: 3932: 3925: 3884: 3880: 3849: 3845: 3814:(8): CD011737. 3800: 3796: 3785: 3769: 3765: 3720: 3716: 3710: 3706: 3669: 3665: 3636: 3635: 3631: 3621: 3619: 3606: 3605: 3601: 3588: 3587: 3580: 3549:(968): 357–62. 3535: 3524: 3487: 3470: 3463: 3439: 3435: 3427: 3423: 3376: 3372: 3327: 3318: 3271: 3267: 3242:10.1038/ng.3396 3230:Nature Genetics 3225: 3219: 3215: 3162: 3155: 3108: 3104: 3073: 3069: 3062: 3040: 3036: 2986: 2982: 2966: 2965: 2923: 2919: 2872: 2865: 2820: 2813: 2776:Pharmacotherapy 2768: 2764: 2757: 2743: 2739: 2722: 2721: 2714: 2683:(14): 1483–92. 2669: 2665: 2654: 2636: 2629: 2582: 2578: 2523: 2519: 2466: 2462: 2419: 2415: 2378: 2371: 2326: 2319: 2274: 2267: 2212: 2208: 2163: 2156: 2111: 2102: 2094: 2088: 2077: 2069: 2006: 1961: 1954: 1947:"Heart disease" 1945: 1944: 1940: 1935: 1919: 1913:Heart-on-a-chip 1909: 1886: 1885: 1881: 1879: 1878: 7200–7900 1875: 1873: 1872: 6500–7200 1869: 1867: 1866: 5800–6500 1863: 1861: 1860: 5100–5800 1857: 1855: 1854: 4400–5100 1851: 1849: 1848: 3700–4400 1845: 1843: 1842: 3000–3700 1839: 1837: 1836: 2300–3000 1833: 1831: 1830: 1650–2300 1827: 1825: 1821: 1819: 1815: 1813: 1809: 1798: 1797: 1793: 1791: 1787: 1785: 1781: 1779: 1775: 1773: 1769: 1767: 1763: 1761: 1757: 1755: 1751: 1749: 1748: 926–1,148 1745: 1743: 1739: 1730: 1687: 1627: 1614: 1564:HDL cholesterol 1560:CETP Inhibitors 1540: 1528: 1430: 1416: 1359:HDL cholesterol 1312: 1264: 1231: 1229:Pathophysiology 1176: 1151: 1107:carbon monoxide 1071: 1037: 1028: 1022: 1009: 976: 965: 961: 957: 953: 949: 937: 928: 916:sleep disorders 896: 880: 871: 865: 847: 833: 824: 818: 809: 774: 768: 743: 734: 722:atherosclerosis 708:), undiagnosed 686: 667:rheumatic fever 544:Aortic aneurysm 504: 503: 499: 497: 493: 491: 487: 485: 481: 479: 475: 473: 469: 467: 463: 461: 457: 455: 451: 449: 445: 443: 439: 437: 433: 431: 427: 415: 406:developed world 336:atherosclerosis 40: 37: 28: 23: 22: 15: 12: 11: 5: 14984: 14974: 14973: 14968: 14951: 14950: 14948: 14947: 14942: 14937: 14932: 14927: 14922: 14917: 14912: 14907: 14902: 14897: 14896: 14895: 14885: 14880: 14879: 14878: 14868: 14863: 14858: 14853: 14848: 14843: 14838: 14833: 14828: 14823: 14818: 14813: 14812: 14811: 14801: 14796: 14795: 14794: 14789: 14784: 14779: 14774: 14769: 14764: 14759: 14754: 14749: 14744: 14734: 14729: 14727:Binge drinking 14724: 14719: 14714: 14709: 14703: 14701: 14697: 14696: 14687: 14686: 14679: 14672: 14664: 14655: 14654: 14652: 14651: 14646: 14640: 14637: 14636: 14634: 14633: 14628: 14623: 14618: 14613: 14607: 14604: 14603: 14601: 14600: 14594: 14591: 14590: 14588: 14587: 14582: 14577: 14571: 14568: 14567: 14565: 14564: 14559: 14557:Breast disease 14554: 14549: 14543: 14540: 14539: 14537: 14536: 14531: 14525: 14522: 14521: 14519: 14518: 14512: 14509: 14508: 14506: 14505: 14500: 14494: 14491: 14490: 14488: 14487: 14482: 14477: 14471: 14468: 14467: 14465: 14464: 14458: 14455: 14454: 14452: 14451: 14445: 14442: 14441: 14439: 14438: 14433: 14428: 14423: 14417: 14414: 14413: 14411: 14410: 14405: 14399: 14396: 14395: 14393: 14392: 14387: 14381: 14378: 14377: 14372: 14371: 14364: 14357: 14349: 14340: 14339: 14336: 14335: 14333: 14332: 14331: 14330: 14318: 14313: 14308: 14303: 14297: 14295: 14289: 14288: 14286: 14285: 14284: 14283: 14271: 14266: 14265: 14264: 14252: 14245: 14244: 14243: 14231: 14230: 14229: 14217: 14216: 14215: 14210: 14197: 14195: 14186: 14180: 14179: 14176: 14175: 14173: 14172: 14167: 14166: 14165: 14153: 14148: 14143: 14134: 14132: 14128: 14127: 14125: 14124: 14119: 14103: 14101: 14095: 14094: 14092: 14091: 14086: 14080:Janeway lesion 14077: 14065: 14063: 14056: 14055: 14053: 14052: 14047: 14042: 14037: 14032: 14027: 14021: 14019: 14010: 14004: 14003: 14001: 14000: 13998:Template:Shock 13994: 13989: 13984: 13979: 13973: 13971: 13965: 13964: 13962: 13961: 13959: 13954: 13953: 13952: 13950:Cannon A waves 13942: 13937: 13936: 13935: 13924: 13922: 13918: 13917: 13915: 13914: 13909: 13908: 13907: 13902: 13892: 13887: 13882: 13876: 13874: 13868: 13867: 13865: 13864: 13863: 13862: 13852: 13847: 13842: 13841: 13840: 13839: 13838: 13826: 13821: 13816: 13815: 13814: 13809: 13799: 13798: 13797: 13795:Still's murmur 13792: 13777: 13776: 13775: 13770: 13765: 13760: 13749: 13747: 13741: 13740: 13738: 13737: 13736: 13735: 13725: 13719: 13717: 13711: 13710: 13699: 13698: 13691: 13684: 13676: 13667: 13666: 13664: 13663: 13658: 13653: 13652: 13651: 13646: 13636: 13630: 13628: 13624: 13623: 13621: 13620: 13615: 13614: 13613: 13603: 13598: 13597: 13596: 13591: 13586: 13584:herpes simplex 13581: 13571: 13565: 13563: 13559: 13558: 13555: 13554: 13552: 13551: 13550: 13549: 13544: 13532: 13526: 13524: 13518: 13517: 13515: 13514: 13509: 13503: 13501: 13499:Nervous system 13495: 13494: 13492: 13491: 13486: 13480: 13478: 13467: 13466: 13464: 13463: 13458: 13453: 13447: 13445: 13439: 13438: 13436: 13435: 13430: 13429: 13428: 13418: 13412: 13411: 13410: 13409: 13404: 13394: 13389: 13388: 13387: 13382: 13377: 13372: 13367: 13356: 13355: 13349: 13347: 13336: 13335: 13333: 13332: 13327: 13321: 13319: 13317:Cardiovascular 13313: 13312: 13310: 13309: 13304: 13299: 13298: 13297: 13292: 13280: 13275: 13270: 13265: 13259: 13257: 13248: 13244: 13243: 13241: 13240: 13239: 13238: 13233: 13223: 13222: 13221: 13216: 13211: 13206: 13193: 13191: 13185: 13184: 13182: 13181: 13176: 13167: 13157: 13155: 13151: 13150: 13147: 13146: 13144: 13143: 13138: 13133: 13127: 13125: 13115: 13114: 13112: 13111: 13106: 13101: 13095: 13093: 13089:umbilical cord 13083: 13082: 13080: 13079: 13073: 13071: 13057: 13056: 13054: 13053: 13048: 13043: 13037: 13035: 13022: 13014: 13013: 13001: 13000: 12993: 12986: 12978: 12969: 12968: 12965: 12964: 12962: 12961: 12955: 12953: 12947: 12946: 12944: 12943: 12938: 12933: 12928: 12923: 12922: 12921: 12911: 12906: 12901: 12896: 12890: 12888: 12879: 12877:Blood pressure 12873: 12872: 12870: 12869: 12864: 12859: 12854: 12853: 12852: 12847: 12842: 12832: 12831: 12830: 12825: 12814: 12812: 12808: 12807: 12804: 12803: 12801: 12800: 12795: 12790: 12785: 12780: 12774: 12772: 12768: 12767: 12765: 12764: 12759: 12758: 12757: 12752: 12747: 12737: 12731: 12729: 12727:Varicose veins 12723: 12722: 12720: 12719: 12714: 12713: 12712: 12702: 12701: 12700: 12695: 12685: 12684: 12683: 12678: 12673: 12668: 12663: 12653: 12652: 12651: 12640: 12638: 12627: 12626: 12624: 12623: 12617: 12615: 12606: 12600: 12599: 12596: 12595: 12593: 12592: 12590:Spider angioma 12587: 12582: 12576: 12574: 12572:Vascular nevus 12568: 12567: 12565: 12564: 12563: 12562: 12557: 12550:Telangiectasia 12547: 12542: 12536: 12534: 12528: 12527: 12525: 12524: 12523: 12522: 12517: 12512: 12507: 12502: 12492: 12487: 12485:Aortic rupture 12482: 12477: 12476: 12475: 12470: 12465: 12450: 12448: 12446:pseudoaneurysm 12433: 12432: 12429: 12428: 12426: 12425: 12420: 12415: 12410: 12405: 12399: 12397: 12393: 12392: 12390: 12389: 12384: 12378: 12376: 12370: 12369: 12367: 12366: 12365: 12364: 12359: 12357:Oxycholesterol 12354: 12349: 12344: 12339: 12329: 12323: 12322: 12321: 12320: 12315: 12310: 12305: 12300: 12289: 12287: 12278: 12272: 12271: 12269: 12268: 12263: 12262: 12261: 12250: 12248: 12239: 12224: 12223: 12215: 12214: 12207: 12200: 12192: 12183: 12182: 12180: 12179: 12174: 12169: 12168: 12167: 12165:Cardiac asthma 12162: 12152: 12146: 12144: 12140: 12139: 12137: 12136: 12131: 12130: 12129: 12124: 12114: 12113: 12112: 12107: 12102: 12091: 12089: 12083: 12082: 12079: 12078: 12076: 12075: 12073:Strain pattern 12070: 12069: 12068: 12063: 12058: 12046: 12045: 12044: 12032: 12031: 12030: 12018: 12017: 12016: 12011: 11998: 11996: 11992: 11991: 11989: 11988: 11983: 11978: 11973: 11967: 11965: 11963:Cardiac arrest 11959: 11958: 11956: 11955: 11950: 11945: 11943:Andersen–Tawil 11939: 11937: 11931: 11930: 11928: 11927: 11922: 11917: 11912: 11907: 11897: 11895: 11889: 11888: 11886: 11885: 11880: 11879: 11878: 11868: 11863: 11861:Atrial flutter 11857: 11855: 11848: 11847: 11845: 11844: 11839: 11833: 11831: 11825: 11824: 11822: 11821: 11816: 11811: 11805: 11803: 11799: 11798: 11795: 11794: 11792: 11791: 11786: 11781: 11775: 11773: 11767: 11766: 11764: 11763: 11762: 11761: 11756: 11746: 11745: 11744: 11733: 11731: 11722: 11706: 11705: 11703: 11702: 11697: 11696: 11695: 11690: 11685: 11680: 11675: 11670: 11660: 11655: 11654: 11653: 11648: 11643: 11633: 11624: 11619: 11613: 11611: 11602: 11591: 11590: 11587: 11586: 11583: 11582: 11580: 11579: 11578: 11577: 11572: 11560: 11559: 11558: 11553: 11541: 11540: 11539: 11534: 11522: 11521: 11520: 11515: 11510: 11497: 11495: 11491: 11490: 11488: 11487: 11486: 11485: 11480: 11468: 11467: 11466: 11453: 11451: 11442: 11431: 11430: 11428: 11427: 11422: 11421: 11420: 11415: 11410: 11405: 11400: 11395: 11390: 11385: 11384: 11383: 11371:Cardiomyopathy 11368: 11367: 11366: 11364:Chagas disease 11355: 11353: 11347: 11346: 11344: 11343: 11342: 11341: 11336: 11326: 11325: 11324: 11315: 11304: 11302: 11293: 11289: 11288: 11285: 11284: 11282: 11281: 11280: 11279: 11274: 11264: 11263: 11262: 11252: 11251: 11250: 11245: 11234: 11232: 11226: 11225: 11223: 11222: 11221: 11220: 11215: 11205: 11204: 11203: 11198: 11187: 11185: 11181: 11180: 11178: 11177: 11172: 11167: 11162: 11156: 11151: 11144: 11142: 11135: 11129: 11128: 11120: 11119: 11112: 11105: 11097: 11088: 11087: 11084: 11083: 11072: 11061: 11046: 11030: 11025: 11024: 11022: 11021:Classification 11015: 11014: 11009: 11004: 10995: 10990: 10983: 10982:External links 10980: 10977: 10976: 10933: 10884: 10855:(3): 133–144. 10835: 10794: 10751: 10725: 10668: 10665:. 31 May 2017. 10650: 10643: 10620: 10563: 10506: 10465: 10424: 10383: 10362:(4): 440–446. 10342: 10307: 10286:(12): 824–34. 10266: 10237:(7): e004224. 10217: 10168: 10119: 10070: 10021: 9969: 9920: 9871: 9812: 9760: 9717: 9696:(6): 396–404. 9676: 9625: 9610:. March 2009. 9599: 9560: 9519: 9476: 9427: 9378: 9337: 9307: 9255: 9234:(12): 909–19. 9211: 9154: 9103: 9053: 9009: 8966: 8917: 8865: 8816: 8776: 8684: 8620: 8571: 8542:(3): 225–234. 8522: 8473: 8446: 8419:(6): 398–406. 8402: 8350: 8301: 8242: 8199: 8196:on 2014-12-28. 8180: 8160: 8108: 8059: 8018: 7977: 7936: 7895: 7854: 7811: 7784: 7735: 7668: 7611: 7562: 7510: 7497: 7484: 7433: 7389: 7340: 7313:(8): 699–704. 7297: 7248: 7198: 7155: 7096: 7075: 7050: 7006: 6999:. 2018-04-26. 6984: 6962: 6912: 6871: 6830: 6803:(4): 1447–55. 6786: 6759:(5): 499–506. 6743: 6694: 6665:(10): 979–87. 6640: 6591: 6545: 6496: 6467:(9): 1485–97. 6447: 6424: 6354: 6292: 6230: 6211: 6167: 6114: 6085: 6062: 6041:(8): 1179–81. 6021: 5972: 5951:(3): 272–280. 5931: 5888: 5859:(25): 2631–9. 5839: 5796: 5755: 5714: 5673: 5629: 5588: 5553: 5526: 5483: 5440: 5383: 5334: 5282: 5225: 5176: 5157:(5): 1484–95. 5141: 5090: 5048: 5000: 4971: 4922: 4873: 4838: 4780: 4731: 4665: 4654: 4634: 4588: 4536: 4494: 4483: 4463: 4436:(11): 712–22. 4420: 4371: 4313: 4264: 4208: 4197: 4177: 4128: 4079: 4030: 3981: 3940: 3923: 3878: 3843: 3794: 3783: 3763: 3734:(7455): 1519. 3714: 3704: 3663: 3629: 3599: 3596:on 2012-05-10. 3578: 3522: 3501:(9): 1165–72. 3468: 3461: 3433: 3421: 3370: 3316: 3285:(25): 2634–9. 3265: 3213: 3153: 3122:(6): 1242–57. 3102: 3083:(9): 3248–50. 3067: 3060: 3034: 2980: 2917: 2886:(8): 652–666. 2863: 2811: 2762: 2755: 2737: 2734:on 2009-11-11. 2712: 2663: 2652: 2627: 2576: 2537:(12): e81970. 2517: 2460: 2413: 2392:(9): 1216–27. 2369: 2317: 2265: 2206: 2154: 2100: 2086: 2004: 1975:(1): e6–e245. 1952: 1937: 1936: 1934: 1931: 1908: 1905: 1884: >7900 1880: 1874: 1868: 1862: 1856: 1850: 1844: 1838: 1832: 1826: 1824: 900–1650 1820: 1814: 1808: 1807: 1792: 1786: 1780: 1774: 1768: 1762: 1756: 1750: 1744: 1738: 1737: 1729: 1726: 1686: 1683: 1679:micronutrients 1626: 1623: 1613: 1610: 1539: 1536: 1527: 1524: 1465:blood pressure 1415: 1412: 1398: 1397: 1393: 1378: 1375: 1372: 1366: 1355: 1351: 1347: 1339: 1322:, such as the 1318:Maintaining a 1311: 1308: 1263: 1260: 1252:kidney disease 1230: 1227: 1195:cardiomyopathy 1175: 1172: 1150: 1147: 1079:engine exhaust 1070: 1067: 1054: 1053: 1050: 1047: 1044: 1036: 1033: 1024:Main article: 1021: 1018: 1008: 1005: 975: 972: 968:carotid artery 963: 959: 955: 951: 947: 936: 933: 927: 924: 895: 892: 884:celiac disease 879: 878:Celiac disease 876: 864: 861: 832: 829: 817: 814: 808: 805: 767: 764: 742: 739: 733: 730: 710:celiac disease 706:hyperlipidemia 685: 682: 681: 680: 660: 654: 649: 648: 647: 637: 615: 609: 588: 582: 576: 570: 564:blood pressure 557: 554:Cardiomyopathy 547: 546: 541: 536: 526: 520: 498: 492: 486: 480: 474: 468: 462: 456: 450: 444: 438: 432: 426: 425: 414: 411: 379:healthy eating 296:cardiomyopathy 251: 250: 247: 243: 242: 240:blood thinners 229: 223: 222: 208: 204: 203: 200:Healthy eating 197: 193: 192: 174: 168: 167: 161:cardiomyopathy 138: 134: 133: 130: 126: 125: 122: 116: 115: 98: 92: 91: 86: 80: 79: 56: 55: 47: 46: 38: 26: 9: 6: 4: 3: 2: 14983: 14972: 14969: 14967: 14964: 14963: 14961: 14946: 14943: 14941: 14938: 14936: 14933: 14931: 14928: 14926: 14923: 14921: 14918: 14916: 14915:Schizophrenia 14913: 14911: 14908: 14906: 14903: 14901: 14898: 14894: 14891: 14890: 14889: 14886: 14884: 14881: 14877: 14874: 14873: 14872: 14869: 14867: 14864: 14862: 14859: 14857: 14854: 14852: 14849: 14847: 14844: 14842: 14839: 14837: 14834: 14832: 14829: 14827: 14824: 14822: 14819: 14817: 14814: 14810: 14807: 14806: 14805: 14802: 14800: 14797: 14793: 14790: 14788: 14785: 14783: 14780: 14778: 14775: 14773: 14770: 14768: 14765: 14763: 14760: 14758: 14755: 14753: 14750: 14748: 14745: 14743: 14740: 14739: 14738: 14735: 14733: 14730: 14728: 14725: 14723: 14720: 14718: 14715: 14713: 14710: 14708: 14705: 14704: 14702: 14698: 14693: 14685: 14680: 14678: 14673: 14671: 14666: 14665: 14662: 14650: 14649:Fetal disease 14647: 14645: 14642: 14641: 14638: 14632: 14629: 14627: 14624: 14622: 14619: 14617: 14614: 14612: 14609: 14608: 14605: 14599: 14596: 14595: 14592: 14586: 14583: 14581: 14578: 14576: 14573: 14572: 14569: 14563: 14560: 14558: 14555: 14553: 14550: 14548: 14545: 14544: 14541: 14535: 14532: 14530: 14527: 14526: 14523: 14517: 14514: 14513: 14510: 14504: 14501: 14499: 14496: 14495: 14492: 14486: 14483: 14481: 14478: 14476: 14473: 14472: 14469: 14463: 14460: 14459: 14456: 14450: 14447: 14446: 14443: 14437: 14434: 14432: 14429: 14427: 14424: 14422: 14419: 14418: 14415: 14409: 14406: 14404: 14401: 14400: 14397: 14391: 14388: 14386: 14383: 14382: 14379: 14370: 14365: 14363: 14358: 14356: 14351: 14350: 14347: 14329: 14326: 14325: 14324: 14323: 14319: 14317: 14314: 14312: 14309: 14307: 14306:Caput medusae 14304: 14302: 14299: 14298: 14296: 14294: 14290: 14282: 14279: 14278: 14277: 14276: 14272: 14270: 14267: 14263: 14262:Lines of Zahn 14260: 14259: 14258: 14257: 14253: 14251: 14250: 14246: 14242: 14239: 14238: 14237: 14236: 14232: 14228: 14225: 14224: 14223: 14222: 14218: 14214: 14213:Oliver's sign 14211: 14209: 14206: 14205: 14204: 14203: 14199: 14198: 14196: 14194: 14190: 14187: 14185: 14181: 14171: 14168: 14164: 14161: 14160: 14159: 14158: 14154: 14152: 14149: 14147: 14144: 14142: 14140: 14136: 14135: 14133: 14129: 14123: 14120: 14118: 14115: 14113: 14109: 14105: 14104: 14102: 14100: 14096: 14090: 14087: 14085: 14081: 14078: 14076: 14073: 14071: 14067: 14066: 14064: 14062: 14057: 14051: 14048: 14046: 14043: 14041: 14040:MΓΌller's sign 14038: 14036: 14033: 14031: 14028: 14026: 14023: 14022: 14020: 14018: 14014: 14011: 14009: 14005: 13999: 13995: 13993: 13990: 13988: 13985: 13983: 13980: 13978: 13975: 13974: 13972: 13970: 13966: 13960: 13958: 13955: 13951: 13948: 13947: 13946: 13943: 13941: 13940:CΕ“ur en sabot 13938: 13934: 13931: 13930: 13929: 13926: 13925: 13923: 13919: 13913: 13910: 13906: 13903: 13901: 13898: 13897: 13896: 13893: 13891: 13888: 13886: 13883: 13881: 13878: 13877: 13875: 13873: 13869: 13861: 13858: 13857: 13856: 13853: 13851: 13848: 13846: 13843: 13837: 13834: 13833: 13832: 13831: 13827: 13825: 13822: 13820: 13817: 13813: 13810: 13808: 13805: 13804: 13803: 13800: 13796: 13793: 13791: 13788: 13787: 13786: 13783: 13782: 13781: 13778: 13774: 13773:Gallop rhythm 13771: 13769: 13766: 13764: 13761: 13759: 13756: 13755: 13754: 13751: 13750: 13748: 13746: 13742: 13734: 13733:Levine's sign 13731: 13730: 13729: 13726: 13724: 13723:Referred pain 13721: 13720: 13718: 13716: 13712: 13708: 13704: 13697: 13692: 13690: 13685: 13683: 13678: 13677: 13674: 13662: 13659: 13657: 13654: 13650: 13647: 13645: 13642: 13641: 13640: 13637: 13635: 13632: 13631: 13629: 13625: 13619: 13616: 13612: 13609: 13608: 13607: 13604: 13602: 13599: 13595: 13592: 13590: 13587: 13585: 13582: 13580: 13577: 13576: 13575: 13572: 13570: 13567: 13566: 13564: 13560: 13548: 13545: 13543: 13540: 13539: 13538: 13537: 13533: 13531: 13528: 13527: 13525: 13523: 13519: 13513: 13510: 13508: 13505: 13504: 13502: 13500: 13496: 13490: 13487: 13485: 13482: 13481: 13479: 13477: 13472: 13468: 13462: 13459: 13457: 13454: 13452: 13449: 13448: 13446: 13444: 13440: 13434: 13431: 13427: 13424: 13423: 13422: 13419: 13417: 13414: 13413: 13408: 13405: 13403: 13400: 13399: 13398: 13395: 13393: 13390: 13386: 13383: 13381: 13378: 13376: 13373: 13371: 13368: 13366: 13363: 13362: 13361: 13358: 13357: 13354: 13351: 13350: 13348: 13346: 13341: 13337: 13331: 13328: 13326: 13323: 13322: 13320: 13318: 13314: 13308: 13305: 13303: 13300: 13296: 13293: 13291: 13288: 13287: 13286: 13285: 13281: 13279: 13276: 13274: 13271: 13269: 13266: 13264: 13261: 13260: 13258: 13256: 13252: 13249: 13245: 13237: 13234: 13232: 13229: 13228: 13227: 13224: 13220: 13217: 13215: 13212: 13210: 13207: 13205: 13202: 13201: 13200: 13199: 13195: 13194: 13192: 13190: 13186: 13180: 13177: 13175: 13171: 13170:Preterm birth 13168: 13166: 13162: 13159: 13158: 13156: 13152: 13142: 13139: 13137: 13134: 13132: 13129: 13128: 13126: 13123: 13122: 13116: 13110: 13107: 13105: 13102: 13100: 13097: 13096: 13094: 13091: 13090: 13084: 13078: 13075: 13074: 13072: 13069: 13068: 13064: 13058: 13052: 13049: 13047: 13044: 13042: 13039: 13038: 13036: 13033: 13032: 13026: 13023: 13015: 13011: 13010:fetal disease 13007: 12999: 12994: 12992: 12987: 12985: 12980: 12979: 12976: 12960: 12957: 12956: 12954: 12952: 12948: 12942: 12939: 12937: 12934: 12932: 12929: 12927: 12924: 12920: 12917: 12916: 12915: 12912: 12910: 12907: 12905: 12902: 12900: 12897: 12895: 12892: 12891: 12889: 12887: 12883: 12880: 12878: 12874: 12868: 12865: 12863: 12860: 12858: 12855: 12851: 12848: 12846: 12843: 12841: 12838: 12837: 12836: 12833: 12829: 12826: 12824: 12821: 12820: 12819: 12816: 12815: 12813: 12809: 12799: 12796: 12794: 12791: 12789: 12786: 12784: 12781: 12779: 12776: 12775: 12773: 12769: 12763: 12760: 12756: 12753: 12751: 12748: 12746: 12745:Caput medusae 12743: 12742: 12741: 12738: 12736: 12733: 12732: 12730: 12728: 12724: 12718: 12715: 12711: 12708: 12707: 12706: 12703: 12699: 12696: 12694: 12691: 12690: 12689: 12686: 12682: 12679: 12677: 12674: 12672: 12669: 12667: 12664: 12662: 12659: 12658: 12657: 12654: 12650: 12647: 12646: 12645: 12642: 12641: 12639: 12637: 12632: 12628: 12622: 12619: 12618: 12616: 12614: 12610: 12607: 12605: 12601: 12591: 12588: 12586: 12583: 12581: 12578: 12577: 12575: 12573: 12569: 12561: 12558: 12556: 12553: 12552: 12551: 12548: 12546: 12543: 12541: 12538: 12537: 12535: 12533: 12529: 12521: 12518: 12516: 12513: 12511: 12508: 12506: 12503: 12501: 12498: 12497: 12496: 12493: 12491: 12488: 12486: 12483: 12481: 12478: 12474: 12471: 12469: 12466: 12464: 12461: 12460: 12459: 12455: 12452: 12451: 12449: 12447: 12442: 12438: 12434: 12424: 12421: 12419: 12416: 12414: 12411: 12409: 12408:Degos disease 12406: 12404: 12401: 12400: 12398: 12394: 12388: 12385: 12383: 12380: 12379: 12377: 12375: 12371: 12363: 12360: 12358: 12355: 12353: 12350: 12348: 12345: 12343: 12340: 12338: 12335: 12334: 12333: 12330: 12328: 12325: 12324: 12319: 12316: 12314: 12311: 12309: 12306: 12304: 12301: 12299: 12296: 12295: 12294: 12291: 12290: 12288: 12286: 12282: 12279: 12277: 12273: 12267: 12264: 12260: 12257: 12256: 12255: 12252: 12251: 12249: 12247: 12243: 12240: 12238: 12233: 12229: 12225: 12220: 12213: 12208: 12206: 12201: 12199: 12194: 12193: 12190: 12178: 12175: 12173: 12170: 12166: 12163: 12161: 12158: 12157: 12156: 12155:Heart failure 12153: 12151: 12148: 12147: 12145: 12141: 12135: 12132: 12128: 12125: 12123: 12120: 12119: 12118: 12115: 12111: 12108: 12106: 12103: 12101: 12098: 12097: 12096: 12093: 12092: 12090: 12088: 12084: 12074: 12071: 12067: 12066:ST depression 12064: 12062: 12059: 12057: 12054: 12053: 12052: 12051: 12047: 12043: 12040: 12039: 12038: 12037: 12033: 12029: 12026: 12025: 12024: 12023: 12019: 12015: 12012: 12010: 12007: 12006: 12005: 12004: 12000: 11999: 11997: 11993: 11987: 11984: 11982: 11979: 11977: 11974: 11972: 11969: 11968: 11966: 11964: 11960: 11954: 11951: 11949: 11946: 11944: 11941: 11940: 11938: 11936: 11932: 11926: 11923: 11921: 11918: 11916: 11913: 11911: 11908: 11906: 11902: 11899: 11898: 11896: 11894: 11890: 11884: 11881: 11877: 11874: 11873: 11872: 11869: 11867: 11864: 11862: 11859: 11858: 11856: 11854: 11849: 11843: 11840: 11838: 11835: 11834: 11832: 11830: 11826: 11820: 11817: 11815: 11812: 11810: 11807: 11806: 11804: 11800: 11790: 11787: 11785: 11782: 11780: 11777: 11776: 11774: 11772: 11768: 11760: 11757: 11755: 11752: 11751: 11750: 11747: 11743: 11740: 11739: 11738: 11735: 11734: 11732: 11730: 11726: 11723: 11720: 11716: 11711: 11707: 11701: 11698: 11694: 11693:Trifascicular 11691: 11689: 11686: 11684: 11681: 11679: 11676: 11674: 11671: 11669: 11666: 11665: 11664: 11661: 11659: 11656: 11652: 11649: 11647: 11644: 11642: 11639: 11638: 11637: 11634: 11632: 11628: 11625: 11623: 11620: 11618: 11615: 11614: 11612: 11610: 11606: 11603: 11601: 11596: 11592: 11576: 11575:regurgitation 11573: 11571: 11568: 11567: 11566: 11565: 11561: 11557: 11556:regurgitation 11554: 11552: 11549: 11548: 11547: 11546: 11542: 11538: 11537:regurgitation 11535: 11533: 11530: 11529: 11528: 11527: 11523: 11519: 11518:regurgitation 11516: 11514: 11511: 11509: 11506: 11505: 11504: 11503: 11499: 11498: 11496: 11492: 11484: 11481: 11479: 11476: 11475: 11474: 11473: 11469: 11465: 11462: 11461: 11460: 11459: 11455: 11454: 11452: 11450: 11446: 11443: 11441: 11436: 11432: 11426: 11423: 11419: 11416: 11414: 11411: 11409: 11406: 11404: 11401: 11399: 11396: 11394: 11391: 11389: 11386: 11382: 11379: 11378: 11377: 11374: 11373: 11372: 11369: 11365: 11362: 11361: 11360: 11357: 11356: 11354: 11352: 11348: 11340: 11337: 11335: 11332: 11331: 11330: 11327: 11323: 11319: 11316: 11314: 11311: 11310: 11309: 11306: 11305: 11303: 11301: 11297: 11294: 11290: 11278: 11275: 11273: 11270: 11269: 11268: 11265: 11261: 11258: 11257: 11256: 11253: 11249: 11246: 11244: 11241: 11240: 11239: 11236: 11235: 11233: 11231: 11227: 11219: 11216: 11214: 11211: 11210: 11209: 11206: 11202: 11201:Stable angina 11199: 11197: 11194: 11193: 11192: 11189: 11188: 11186: 11182: 11176: 11173: 11171: 11168: 11166: 11163: 11160: 11157: 11155: 11152: 11149: 11146: 11145: 11143: 11139: 11136: 11134: 11130: 11125: 11118: 11113: 11111: 11106: 11104: 11099: 11098: 11095: 11082: 11078: 11077: 11073: 11071: 11067: 11066: 11062: 11060: 11056: 11055: 11051: 11047: 11045: 11041: 11040: 11036: 11032: 11031: 11028: 11023: 11019: 11013: 11010: 11008: 11005: 11002: 10999: 10998:Heart Disease 10996: 10994: 10991: 10989: 10986: 10985: 10972: 10968: 10964: 10960: 10956: 10952: 10948: 10944: 10937: 10929: 10925: 10920: 10915: 10911: 10907: 10903: 10899: 10895: 10888: 10880: 10876: 10871: 10866: 10862: 10858: 10854: 10850: 10846: 10839: 10831: 10827: 10822: 10817: 10814:(5): 168–69. 10813: 10809: 10805: 10798: 10790: 10786: 10782: 10778: 10774: 10770: 10766: 10762: 10755: 10740: 10736: 10729: 10721: 10717: 10712: 10707: 10703: 10699: 10695: 10691: 10687: 10683: 10679: 10672: 10664: 10663:www.heart.org 10660: 10654: 10646: 10640: 10636: 10635: 10627: 10625: 10616: 10612: 10608: 10604: 10599: 10594: 10590: 10586: 10582: 10578: 10574: 10567: 10559: 10555: 10551: 10547: 10543: 10539: 10534: 10529: 10525: 10521: 10517: 10510: 10502: 10498: 10493: 10488: 10485:(9): 686–94. 10484: 10480: 10476: 10469: 10461: 10457: 10452: 10447: 10443: 10439: 10435: 10428: 10420: 10416: 10411: 10406: 10402: 10398: 10394: 10387: 10379: 10375: 10370: 10365: 10361: 10357: 10353: 10346: 10338: 10334: 10330: 10326: 10323:(2): 353–61. 10322: 10318: 10311: 10303: 10299: 10294: 10289: 10285: 10281: 10277: 10270: 10262: 10258: 10254: 10250: 10245: 10240: 10236: 10232: 10228: 10221: 10213: 10209: 10204: 10199: 10195: 10191: 10187: 10183: 10179: 10172: 10164: 10160: 10155: 10150: 10146: 10142: 10138: 10134: 10130: 10123: 10115: 10111: 10106: 10101: 10097: 10093: 10089: 10085: 10081: 10074: 10066: 10062: 10057: 10052: 10048: 10044: 10040: 10036: 10032: 10025: 10017: 10013: 10008: 10003: 9999: 9995: 9991: 9987: 9980: 9973: 9965: 9961: 9956: 9951: 9947: 9943: 9939: 9935: 9931: 9924: 9916: 9912: 9907: 9902: 9898: 9894: 9890: 9886: 9882: 9875: 9867: 9863: 9858: 9853: 9849: 9845: 9840: 9835: 9831: 9827: 9823: 9816: 9808: 9804: 9799: 9794: 9790: 9786: 9782: 9778: 9774: 9767: 9765: 9749: 9745: 9744: 9740: 9735: 9731: 9727: 9721: 9713: 9709: 9704: 9699: 9695: 9691: 9687: 9680: 9672: 9668: 9663: 9658: 9653: 9648: 9644: 9640: 9636: 9629: 9613: 9609: 9603: 9595: 9591: 9587: 9583: 9579: 9575: 9571: 9564: 9556: 9552: 9547: 9542: 9538: 9534: 9530: 9523: 9515: 9511: 9507: 9503: 9499: 9495: 9491: 9487: 9480: 9472: 9468: 9463: 9458: 9454: 9450: 9446: 9442: 9438: 9431: 9423: 9419: 9414: 9409: 9405: 9401: 9397: 9393: 9389: 9382: 9374: 9370: 9365: 9360: 9356: 9352: 9348: 9341: 9325: 9321: 9317: 9311: 9303: 9299: 9294: 9289: 9285: 9281: 9277: 9273: 9266: 9259: 9251: 9247: 9242: 9237: 9233: 9229: 9225: 9218: 9216: 9207: 9203: 9198: 9193: 9189: 9185: 9181: 9177: 9173: 9169: 9165: 9158: 9150: 9146: 9141: 9136: 9131: 9126: 9123:(4): 878–85. 9122: 9118: 9114: 9107: 9099: 9095: 9091: 9087: 9083: 9079: 9075: 9071: 9067: 9060: 9058: 9049: 9045: 9041: 9037: 9033: 9029: 9025: 9021: 9013: 9005: 9001: 8997: 8993: 8989: 8985: 8981: 8977: 8970: 8962: 8958: 8953: 8948: 8944: 8940: 8936: 8932: 8928: 8921: 8913: 8909: 8904: 8899: 8895: 8891: 8887: 8883: 8879: 8872: 8870: 8861: 8857: 8852: 8847: 8843: 8839: 8835: 8831: 8827: 8820: 8812: 8807: 8802: 8799:(2): 530–52. 8798: 8794: 8790: 8783: 8781: 8768: 8760: 8753: 8749: 8745: 8741: 8737: 8730: 8726: 8722: 8718: 8714: 8710: 8707:(3): 221–30. 8706: 8702: 8695: 8688: 8674:on 2013-12-20 8670: 8666: 8662: 8658: 8654: 8650: 8646: 8642: 8638: 8631: 8624: 8616: 8612: 8607: 8602: 8598: 8594: 8590: 8586: 8582: 8575: 8567: 8563: 8558: 8553: 8549: 8545: 8541: 8537: 8533: 8526: 8518: 8514: 8509: 8504: 8500: 8496: 8492: 8488: 8484: 8477: 8469: 8465: 8461: 8457: 8450: 8442: 8438: 8434: 8430: 8426: 8422: 8418: 8414: 8406: 8398: 8394: 8390: 8386: 8381: 8376: 8373:(3): e1–e23. 8372: 8368: 8364: 8357: 8355: 8346: 8342: 8337: 8332: 8328: 8324: 8320: 8316: 8312: 8305: 8297: 8293: 8288: 8283: 8279: 8275: 8270: 8265: 8261: 8257: 8253: 8246: 8238: 8234: 8230: 8226: 8222: 8218: 8214: 8210: 8203: 8195: 8191: 8187: 8183: 8177: 8173: 8172: 8164: 8156: 8152: 8147: 8142: 8138: 8134: 8130: 8126: 8122: 8115: 8113: 8104: 8100: 8095: 8090: 8086: 8082: 8078: 8074: 8070: 8063: 8055: 8051: 8046: 8041: 8038:(2): 343–52. 8037: 8033: 8029: 8022: 8014: 8010: 8005: 8000: 7996: 7992: 7988: 7981: 7973: 7969: 7964: 7959: 7955: 7951: 7950:Diabetes Care 7947: 7940: 7932: 7928: 7923: 7918: 7914: 7910: 7906: 7899: 7891: 7887: 7882: 7877: 7873: 7869: 7865: 7858: 7850: 7846: 7842: 7838: 7834: 7830: 7826: 7822: 7815: 7807: 7803: 7799: 7795: 7788: 7780: 7776: 7771: 7766: 7762: 7758: 7754: 7750: 7746: 7739: 7731: 7727: 7722: 7717: 7713: 7709: 7704: 7699: 7695: 7691: 7687: 7683: 7679: 7672: 7664: 7660: 7655: 7650: 7646: 7642: 7638: 7634: 7630: 7626: 7622: 7615: 7607: 7603: 7598: 7593: 7589: 7585: 7581: 7577: 7573: 7566: 7558: 7554: 7549: 7544: 7540: 7536: 7532: 7528: 7521: 7514: 7507: 7501: 7494: 7488: 7480: 7476: 7471: 7466: 7461: 7456: 7453:(5): 341–51. 7452: 7448: 7444: 7437: 7429: 7425: 7421: 7417: 7413: 7409: 7406:(2): 215–33. 7405: 7401: 7393: 7385: 7381: 7376: 7371: 7367: 7363: 7359: 7355: 7351: 7344: 7336: 7332: 7328: 7324: 7320: 7316: 7312: 7308: 7301: 7293: 7289: 7284: 7279: 7275: 7271: 7268:(2): 187–92. 7267: 7263: 7259: 7252: 7244: 7240: 7236: 7232: 7228: 7224: 7220: 7216: 7209: 7202: 7194: 7190: 7186: 7182: 7178: 7174: 7171:(7): 745–52. 7170: 7166: 7159: 7152: 7147: 7141: 7137: 7132: 7127: 7123: 7119: 7115: 7111: 7107: 7100: 7085: 7079: 7064: 7060: 7054: 7046: 7042: 7037: 7032: 7028: 7024: 7020: 7013: 7011: 7002: 6998: 6994: 6988: 6980: 6976: 6972: 6966: 6958: 6954: 6950: 6946: 6939: 6935: 6931: 6927: 6923: 6916: 6908: 6904: 6899: 6894: 6890: 6886: 6882: 6875: 6867: 6863: 6858: 6853: 6849: 6845: 6841: 6834: 6826: 6822: 6818: 6814: 6810: 6806: 6802: 6798: 6790: 6782: 6778: 6774: 6770: 6766: 6762: 6758: 6754: 6747: 6739: 6735: 6730: 6725: 6721: 6717: 6713: 6709: 6705: 6698: 6690: 6686: 6681: 6676: 6672: 6668: 6664: 6660: 6656: 6649: 6647: 6645: 6636: 6632: 6627: 6622: 6618: 6614: 6610: 6606: 6602: 6595: 6587: 6583: 6578: 6573: 6569: 6565: 6561: 6557: 6549: 6541: 6537: 6532: 6527: 6523: 6519: 6515: 6511: 6507: 6500: 6492: 6488: 6484: 6480: 6475: 6470: 6466: 6462: 6458: 6451: 6445: 6442: 6440: 6434: 6428: 6420: 6416: 6411: 6406: 6402: 6398: 6393: 6388: 6384: 6380: 6376: 6372: 6368: 6361: 6359: 6350: 6346: 6341: 6336: 6332: 6328: 6323: 6318: 6314: 6310: 6306: 6299: 6297: 6288: 6284: 6279: 6274: 6270: 6266: 6261: 6256: 6252: 6248: 6244: 6237: 6235: 6226: 6220: 6218: 6216: 6207: 6203: 6199: 6195: 6191: 6187: 6183: 6179: 6171: 6163: 6159: 6154: 6149: 6145: 6141: 6137: 6133: 6129: 6125: 6118: 6110: 6104: 6096: 6092: 6088: 6082: 6078: 6071: 6069: 6067: 6058: 6054: 6049: 6044: 6040: 6036: 6032: 6025: 6017: 6013: 6008: 6003: 5999: 5995: 5991: 5987: 5983: 5976: 5968: 5964: 5959: 5954: 5950: 5946: 5942: 5935: 5927: 5923: 5919: 5915: 5911: 5907: 5904:(11): 611–9. 5903: 5899: 5892: 5884: 5880: 5876: 5872: 5867: 5862: 5858: 5854: 5850: 5843: 5835: 5831: 5827: 5823: 5819: 5815: 5812:(6): 438–47. 5811: 5807: 5800: 5792: 5788: 5783: 5778: 5774: 5770: 5766: 5759: 5751: 5747: 5742: 5737: 5733: 5729: 5725: 5718: 5710: 5706: 5701: 5696: 5692: 5688: 5684: 5677: 5669: 5665: 5661: 5657: 5653: 5649: 5645: 5641: 5633: 5625: 5621: 5616: 5611: 5608:(4): 585–91. 5607: 5603: 5599: 5592: 5584: 5580: 5576: 5572: 5568: 5564: 5557: 5541: 5537: 5530: 5522: 5518: 5514: 5510: 5506: 5502: 5498: 5494: 5487: 5479: 5475: 5471: 5467: 5463: 5459: 5456:(5): 718–23. 5455: 5451: 5444: 5436: 5432: 5427: 5422: 5418: 5414: 5410: 5406: 5403:(6): 576–83. 5402: 5398: 5394: 5387: 5379: 5375: 5370: 5365: 5361: 5357: 5353: 5349: 5345: 5338: 5330: 5326: 5321: 5316: 5312: 5308: 5304: 5300: 5296: 5289: 5287: 5271: 5267: 5263: 5259: 5255: 5251: 5247: 5243: 5242:RadioGraphics 5239: 5232: 5230: 5221: 5217: 5212: 5207: 5203: 5199: 5195: 5191: 5187: 5180: 5172: 5168: 5164: 5160: 5156: 5152: 5145: 5137: 5133: 5128: 5123: 5118: 5113: 5109: 5105: 5101: 5094: 5080:on 2017-06-06 5079: 5075: 5071: 5067: 5061: 5059: 5057: 5055: 5053: 5037: 5033: 5029: 5025: 5019: 5017: 5015: 5013: 5011: 5009: 5007: 5005: 4989: 4985: 4981: 4975: 4967: 4963: 4958: 4953: 4949: 4945: 4942:(5): 806–14. 4941: 4937: 4933: 4926: 4918: 4914: 4909: 4904: 4900: 4896: 4892: 4888: 4884: 4877: 4869: 4865: 4861: 4857: 4853: 4849: 4842: 4834: 4827: 4823: 4818: 4813: 4808: 4803: 4799: 4795: 4791: 4784: 4776: 4772: 4767: 4762: 4758: 4754: 4750: 4746: 4742: 4735: 4727: 4720: 4716: 4711: 4706: 4701: 4696: 4692: 4688: 4684: 4680: 4676: 4669: 4661: 4657: 4651: 4647: 4646: 4638: 4630: 4626: 4622: 4618: 4614: 4610: 4606: 4602: 4595: 4593: 4584: 4580: 4575: 4570: 4566: 4562: 4558: 4554: 4550: 4543: 4541: 4532: 4528: 4524: 4520: 4516: 4512: 4505: 4503: 4501: 4499: 4490: 4486: 4480: 4476: 4475: 4467: 4459: 4455: 4451: 4447: 4443: 4439: 4435: 4431: 4424: 4416: 4412: 4408: 4404: 4399: 4394: 4390: 4386: 4382: 4375: 4367: 4363: 4359: 4355: 4350: 4345: 4341: 4337: 4333: 4329: 4322: 4320: 4318: 4309: 4305: 4300: 4295: 4291: 4287: 4283: 4279: 4275: 4268: 4253: 4249: 4244: 4239: 4235: 4231: 4227: 4223: 4219: 4212: 4204: 4200: 4194: 4190: 4189: 4181: 4173: 4169: 4164: 4159: 4155: 4151: 4147: 4143: 4139: 4132: 4124: 4120: 4115: 4110: 4106: 4102: 4098: 4094: 4090: 4083: 4075: 4071: 4066: 4061: 4057: 4053: 4049: 4045: 4041: 4034: 4026: 4022: 4018: 4014: 4009: 4004: 4000: 3996: 3992: 3985: 3977: 3973: 3968: 3963: 3959: 3955: 3951: 3944: 3936: 3930: 3928: 3919: 3915: 3910: 3905: 3901: 3897: 3894:(4): 585–92. 3893: 3889: 3882: 3874: 3870: 3866: 3862: 3859:(6): 448–56. 3858: 3854: 3847: 3839: 3835: 3830: 3825: 3821: 3817: 3813: 3809: 3805: 3798: 3790: 3786: 3780: 3776: 3775: 3767: 3759: 3755: 3750: 3745: 3741: 3737: 3733: 3729: 3725: 3718: 3708: 3700: 3696: 3691: 3686: 3682: 3678: 3674: 3667: 3659: 3655: 3651: 3647: 3643: 3642:NIHR Evidence 3639: 3633: 3617: 3613: 3609: 3603: 3595: 3591: 3585: 3583: 3574: 3570: 3565: 3560: 3556: 3552: 3548: 3544: 3540: 3533: 3531: 3529: 3527: 3518: 3514: 3509: 3504: 3500: 3496: 3492: 3485: 3483: 3481: 3479: 3477: 3475: 3473: 3464: 3458: 3454: 3450: 3446: 3445: 3437: 3431: 3425: 3417: 3413: 3408: 3403: 3398: 3393: 3389: 3385: 3381: 3374: 3366: 3362: 3357: 3352: 3348: 3344: 3341:(2): 934–45. 3340: 3336: 3332: 3325: 3323: 3321: 3312: 3308: 3303: 3298: 3293: 3288: 3284: 3280: 3276: 3269: 3261: 3257: 3252: 3247: 3243: 3239: 3235: 3231: 3224: 3217: 3209: 3205: 3201: 3197: 3193: 3189: 3184: 3179: 3175: 3171: 3167: 3160: 3158: 3149: 3145: 3140: 3135: 3130: 3125: 3121: 3117: 3113: 3106: 3098: 3094: 3090: 3086: 3082: 3078: 3071: 3063: 3057: 3053: 3048: 3047: 3038: 3030: 3026: 3022: 3018: 3013: 3008: 3004: 3000: 2996: 2992: 2984: 2976: 2970: 2962: 2958: 2954: 2950: 2945: 2940: 2936: 2932: 2928: 2921: 2913: 2909: 2904: 2899: 2894: 2889: 2885: 2881: 2877: 2870: 2868: 2859: 2855: 2850: 2845: 2841: 2837: 2834:(6): 515–24. 2833: 2829: 2825: 2818: 2816: 2807: 2803: 2799: 2795: 2790: 2785: 2782:(4): e54-87. 2781: 2777: 2773: 2766: 2758: 2752: 2748: 2741: 2733: 2729: 2725: 2719: 2717: 2708: 2704: 2699: 2694: 2690: 2686: 2682: 2678: 2674: 2667: 2659: 2655: 2649: 2645: 2641: 2634: 2632: 2623: 2619: 2614: 2609: 2605: 2601: 2598:(43): 1–253. 2597: 2593: 2592: 2587: 2580: 2572: 2568: 2563: 2558: 2553: 2548: 2544: 2540: 2536: 2532: 2528: 2521: 2513: 2509: 2504: 2499: 2495: 2491: 2487: 2483: 2479: 2475: 2471: 2464: 2456: 2452: 2448: 2444: 2440: 2436: 2432: 2428: 2424: 2417: 2409: 2405: 2400: 2395: 2391: 2387: 2383: 2376: 2374: 2365: 2361: 2356: 2351: 2347: 2343: 2339: 2335: 2331: 2324: 2322: 2313: 2309: 2304: 2299: 2295: 2291: 2288:(1): 417–40. 2287: 2283: 2279: 2272: 2270: 2261: 2257: 2252: 2247: 2243: 2239: 2234: 2229: 2225: 2221: 2217: 2210: 2202: 2198: 2193: 2188: 2184: 2180: 2176: 2172: 2168: 2161: 2159: 2150: 2146: 2141: 2136: 2132: 2128: 2124: 2120: 2116: 2109: 2107: 2105: 2093: 2089: 2083: 2076: 2075: 2067: 2065: 2063: 2061: 2059: 2057: 2055: 2053: 2051: 2049: 2047: 2045: 2043: 2041: 2039: 2037: 2035: 2033: 2031: 2029: 2027: 2025: 2023: 2021: 2019: 2017: 2015: 2013: 2011: 2009: 2000: 1996: 1991: 1986: 1982: 1978: 1974: 1970: 1966: 1959: 1957: 1948: 1942: 1938: 1930: 1927: 1925: 1918: 1914: 1904: 1902: 1898: 1892: 1818: <900 1812: no data 1804: 1742: 318–925 1734: 1725: 1722: 1720: 1716: 1712: 1707: 1704: 1698: 1696: 1692: 1682: 1680: 1676: 1672: 1668: 1664: 1660: 1656: 1652: 1648: 1644: 1640: 1636: 1632: 1622: 1618: 1609: 1605: 1604: 1600: 1598: 1593: 1591: 1586: 1582: 1580: 1576: 1572: 1568: 1565: 1561: 1557: 1553: 1548: 1544: 1535: 1533: 1523: 1521: 1517: 1512: 1511:low-salt diet 1507: 1505: 1500: 1496: 1495:carbohydrates 1492: 1488: 1487:saturated fat 1483: 1481: 1477: 1473: 1468: 1466: 1462: 1458: 1454: 1449: 1447: 1442: 1437: 1435: 1429: 1425: 1421: 1411: 1408: 1407:periodontitis 1402: 1394: 1391: 1387: 1383: 1379: 1376: 1373: 1370: 1367: 1364: 1360: 1357:Decrease non- 1356: 1352: 1348: 1344: 1343:saturated fat 1340: 1337: 1333: 1329: 1325: 1321: 1317: 1316: 1315: 1307: 1303: 1299: 1297: 1294:(hsCRP), and 1293: 1289: 1285: 1281: 1277: 1273: 1269: 1259: 1257: 1253: 1249: 1244: 1235: 1226: 1224: 1220: 1216: 1212: 1208: 1204: 1200: 1196: 1192: 1188: 1183: 1180: 1171: 1169: 1164: 1160: 1156: 1146: 1144: 1140: 1135: 1133: 1129: 1125: 1124:phenoxy acids 1120: 1116: 1115:tobacco smoke 1112: 1108: 1104: 1100: 1096: 1092: 1088: 1084: 1083:welding fumes 1080: 1076: 1066: 1064: 1063:heart attacks 1059: 1051: 1048: 1045: 1042: 1041: 1040: 1032: 1027: 1017: 1015: 1004: 1002: 998: 994: 990: 986: 982: 981:calcification 971: 969: 945: 941: 935:Air pollution 932: 923: 919: 917: 913: 909: 905: 900: 891: 889: 885: 875: 870: 860: 858: 853: 846: 842: 838: 828: 823: 813: 804: 800: 798: 794: 790: 786: 781: 779: 773: 763: 759: 755: 747: 738: 729: 727: 723: 719: 715: 714:air pollution 711: 707: 703: 699: 695: 691: 678: 674: 673: 668: 664: 661: 658: 655: 653: 650: 645: 641: 638: 635: 631: 627: 623: 619: 616: 614: 611:Inflammatory 610: 607: 603: 599: 595: 592: 591: 589: 586: 583: 580: 577: 574: 573:Heart failure 571: 569: 565: 561: 558: 555: 552: 551: 550: 545: 542: 540: 537: 534: 530: 527: 524: 521: 518: 515: 514: 513: 511: 496: 700–770 490: 630–700 484: 560–630 478: 490–560 472: 420–490 466: 350–420 460: 280–350 454: 210–280 448: 140–210 430: No data 423: 419: 410: 407: 403: 399: 395: 390: 388: 384: 380: 375: 373: 369: 365: 361: 357: 353: 349: 345: 341: 337: 331: 329: 325: 321: 317: 313: 309: 305: 301: 297: 293: 289: 285: 284:heart failure 281: 277: 273: 269: 268:blood vessels 265: 261: 257: 248: 244: 241: 237: 236:beta blockers 233: 230: 228: 224: 221: 217: 213: 209: 205: 201: 198: 194: 190: 186: 182: 178: 175: 173: 169: 166: 162: 158: 154: 150: 149:heart failure 146: 142: 139: 135: 131: 127: 123: 121: 120:Complications 117: 114: 110: 106: 102: 99: 97: 93: 90: 87: 85: 81: 77: 76:Movat's stain 73: 70:(yellow) and 69: 65: 61: 57: 53: 48: 43: 35: 30: 19: 18:Heart disease 14945:Tuberculosis 14856:Malnutrition 14700:Health topic 14692:epidemiology 14631:Chondropathy 14626:Bone disease 14598:Skin disease 14497: 14426:Malnutrition 14403:Benign tumor 14320: 14273: 14269:Adson's sign 14254: 14247: 14241:Allen's test 14233: 14219: 14200: 14155: 14151:Aschoff body 14137: 14122:Ewart's sign 14117:Beck's triad 14106: 14084:Osler's node 14070:endocarditis 14068: 14050:Mayne's sign 14007: 13996:See further 13992:Distributive 13928:Palpitations 13894: 13828: 13780:Heart murmur 13753:Heart sounds 13745:Auscultation 13534: 13316: 13290:Pneumothorax 13282: 13196: 13189:Birth trauma 13131:Breech birth 13121:presentation 13119: 13087: 13061: 13029: 12886:Hypertension 12798:Venous ulcer 12704: 12687: 12655: 12643: 12613:Inflammation 12494: 12453: 12342:Hyperplastic 12303:Fatty streak 12246:Inflammation 12218: 12087:Cardiomegaly 12061:ST elevation 12048: 12034: 12020: 12001: 11905:Ectopic beat 11853:fibrillation 11688:Bifascicular 11562: 11543: 11524: 11500: 11470: 11456: 11449:Endocarditis 11388:Hypertrophic 11322:Constrictive 11308:Pericarditis 11266: 11254: 11237: 11123: 11074: 11063: 11048: 11033: 10949:(2): 73–74. 10946: 10942: 10936: 10904:(2): 71–72. 10901: 10897: 10887: 10852: 10848: 10838: 10811: 10807: 10797: 10764: 10760: 10754: 10743:. Retrieved 10728: 10685: 10681: 10671: 10662: 10653: 10633: 10580: 10576: 10566: 10523: 10519: 10509: 10482: 10478: 10468: 10441: 10437: 10427: 10403:(8): 691–6. 10400: 10396: 10386: 10359: 10355: 10345: 10320: 10316: 10310: 10283: 10279: 10269: 10234: 10230: 10220: 10185: 10181: 10171: 10136: 10132: 10122: 10087: 10083: 10073: 10038: 10034: 10024: 9989: 9985: 9972: 9937: 9933: 9923: 9888: 9884: 9874: 9829: 9825: 9815: 9780: 9776: 9752:, retrieved 9737: 9720: 9693: 9689: 9679: 9642: 9638: 9628: 9616:. Retrieved 9602: 9577: 9573: 9563: 9536: 9533:Diabetologia 9532: 9522: 9489: 9485: 9479: 9444: 9440: 9430: 9395: 9391: 9381: 9357:(4): 291–7. 9354: 9350: 9340: 9328:. Retrieved 9323: 9319: 9310: 9275: 9271: 9258: 9231: 9227: 9171: 9167: 9157: 9120: 9117:Hypertension 9116: 9106: 9073: 9069: 9023: 9019: 9012: 8979: 8975: 8969: 8934: 8930: 8920: 8885: 8881: 8833: 8829: 8819: 8796: 8792: 8765:{{ 8757:{{ 8704: 8700: 8687: 8676:. Retrieved 8669:the original 8640: 8636: 8623: 8588: 8584: 8574: 8539: 8535: 8525: 8490: 8486: 8476: 8459: 8455: 8449: 8416: 8412: 8405: 8370: 8366: 8318: 8314: 8304: 8259: 8255: 8245: 8215:(1): 13–24. 8212: 8208: 8202: 8194:the original 8170: 8163: 8128: 8124: 8076: 8072: 8062: 8035: 8031: 8021: 7997:(3): 223–4. 7994: 7990: 7980: 7953: 7949: 7939: 7912: 7908: 7898: 7871: 7867: 7857: 7828: 7824: 7814: 7800:(7): 571–8. 7797: 7793: 7787: 7752: 7748: 7738: 7685: 7681: 7671: 7628: 7624: 7614: 7579: 7575: 7565: 7530: 7526: 7513: 7500: 7487: 7450: 7446: 7436: 7403: 7399: 7392: 7357: 7353: 7343: 7327:11573/562721 7310: 7306: 7300: 7265: 7261: 7251: 7221:(6): 916–7. 7218: 7214: 7201: 7168: 7164: 7158: 7113: 7109: 7099: 7087:. Retrieved 7078: 7066:. Retrieved 7062: 7053: 7026: 7022: 6996: 6987: 6974: 6965: 6921: 6915: 6888: 6884: 6874: 6847: 6843: 6833: 6800: 6796: 6789: 6756: 6752: 6746: 6711: 6707: 6697: 6662: 6658: 6608: 6604: 6594: 6559: 6555: 6548: 6513: 6509: 6499: 6464: 6460: 6450: 6436: 6427: 6374: 6370: 6315:(11): 3952. 6312: 6308: 6250: 6246: 6181: 6177: 6170: 6135: 6131: 6117: 6076: 6038: 6034: 6024: 5989: 5985: 5975: 5948: 5944: 5934: 5901: 5897: 5891: 5856: 5852: 5842: 5809: 5805: 5799: 5775:(7): 512–8. 5772: 5768: 5758: 5731: 5727: 5717: 5690: 5686: 5676: 5643: 5639: 5632: 5605: 5601: 5591: 5569:(2): 184–8. 5566: 5562: 5556: 5544:. Retrieved 5540:the original 5529: 5499:(1): 43–54. 5496: 5492: 5486: 5453: 5449: 5443: 5400: 5396: 5386: 5351: 5347: 5337: 5302: 5298: 5273:. Retrieved 5245: 5241: 5193: 5189: 5179: 5154: 5150: 5144: 5110:(1): 43–50. 5107: 5103: 5093: 5082:. Retrieved 5078:the original 5073: 5040:. Retrieved 5031: 4992:. Retrieved 4983: 4974: 4939: 4935: 4925: 4890: 4886: 4876: 4851: 4847: 4841: 4797: 4794:BMC Medicine 4793: 4783: 4748: 4744: 4734: 4682: 4678: 4668: 4644: 4637: 4607:(6): 442–4. 4604: 4600: 4556: 4552: 4517:(3): 230–4. 4514: 4510: 4473: 4466: 4433: 4429: 4423: 4388: 4384: 4374: 4331: 4327: 4281: 4277: 4267: 4255:. Retrieved 4225: 4221: 4211: 4187: 4180: 4145: 4141: 4131: 4096: 4092: 4082: 4047: 4043: 4033: 4001:(4): 523–7. 3998: 3994: 3984: 3960:(1): 65–79. 3957: 3953: 3943: 3891: 3887: 3881: 3856: 3852: 3846: 3811: 3807: 3797: 3773: 3766: 3731: 3727: 3717: 3707: 3680: 3677:Hypertension 3676: 3666: 3641: 3632: 3620:. Retrieved 3611: 3602: 3594:the original 3546: 3542: 3498: 3494: 3443: 3436: 3424: 3387: 3383: 3373: 3338: 3334: 3282: 3278: 3268: 3233: 3229: 3216: 3173: 3169: 3119: 3115: 3105: 3080: 3076: 3070: 3045: 3037: 2994: 2990: 2983: 2969:cite journal 2934: 2930: 2920: 2883: 2879: 2831: 2827: 2779: 2775: 2765: 2746: 2740: 2732:the original 2727: 2680: 2676: 2666: 2643: 2595: 2589: 2579: 2534: 2530: 2520: 2477: 2473: 2463: 2430: 2426: 2416: 2389: 2385: 2340:(1): 76–84. 2337: 2333: 2285: 2281: 2226:(12): 4305. 2223: 2219: 2209: 2174: 2170: 2122: 2118: 2073: 1972: 1968: 1941: 1928: 1920: 1893: 1889: 1728:Epidemiology 1723: 1708: 1699: 1688: 1677:, including 1631:healthy diet 1628: 1619: 1615: 1606: 1602: 1601: 1594: 1583: 1579:hypoglycemia 1569: 1545: 1541: 1529: 1515: 1508: 1484: 1469: 1457:low-fat diet 1450: 1438: 1431: 1403: 1399: 1320:healthy diet 1313: 1304: 1300: 1265: 1246:Obesity and 1245: 1241: 1190: 1186: 1184: 1177: 1157:-associated 1152: 1136: 1130:(dioxin) or 1119:electrolytic 1091:benzopyrenes 1072: 1055: 1038: 1029: 1010: 997:homocysteine 977: 938: 929: 920: 901: 897: 881: 872: 848: 825: 810: 801: 782: 775: 760: 756: 752: 735: 698:hypertension 692:, excessive 687: 684:Risk factors 670: 644:eosinophilic 613:cardiomegaly 606:heart valves 598:inflammation 594:Endocarditis 568:hypertension 548: 507: 442: 70–140 391: 376: 372:strep throat 332: 280:heart attack 259: 255: 254: 172:Risk factors 132:Older adults 29: 14836:Hepatitis D 14831:Hepatitis C 14799:Chikungunya 14485:Ear disease 14480:Eye disease 14099:Pericardium 14075:Roth's spot 14061:endocardium 13987:Hypovolemic 13982:Obstructive 13977:Cardiogenic 13885:Bradycardia 13880:Tachycardia 13850:Heart click 13634:Miscarriage 13536:muscle tone 13402:Kernicterus 13255:Respiratory 13231:Erb's palsy 13136:Asynclitism 13104:Nuchal cord 12951:Hypotension 12495:head / neck 12347:Cholesterol 12237:capillaries 11953:Romano–Ward 11920:Parasystole 11819:Ventricular 11771:Ventricular 11710:Tachycardia 11627:Heart block 11609:Bradycardia 11435:Endocardium 11398:Restrictive 11359:Myocarditis 11300:Pericardium 11001:MedicineNet 10438:Circulation 9026:(1): 4–16. 8738:, see 8367:Circulation 7915:(1): 80–9. 7874:(1): 3–10. 7470:10871/19935 6997:NHS Choices 6844:Circulation 6659:Circulation 6562:(1): 20–8. 6184:(1): 20–8. 5728:Circulation 4745:Circulation 4553:Circulation 4349:10906/80012 4278:Circulation 3995:Circulation 3495:Circulation 3453:10665/43007 3279:Circulation 3077:Circulation 3012:10983/21615 2677:Circulation 2386:Circulation 1969:Circulation 1635:antioxidant 1595:The use of 1334:or another 1219:cell damage 1163:blood cells 1126:containing 1075:silica dust 912:sleep apnea 793:endothelial 716:, and poor 669:caused by 618:Myocarditis 602:endocardium 383:antibiotics 129:Usual onset 72:amyloidosis 14960:Categories 14920:Snakebites 14816:Depression 14762:esophageal 14757:colorectal 13957:Hyperaemia 13819:Continuous 13715:Chest pain 13644:Stillbirth 13601:Omphalitis 13562:Infections 13471:Integument 12867:Vasculitis 12857:Thrombosis 12818:Angiopathy 12762:Varicocele 12755:Hemorrhoid 12585:Halo nevus 12441:dissection 12232:arterioles 11851:Flutter / 11814:Junctional 11749:Junctional 11742:Multifocal 11715:paroxysmal 11631:Sinoatrial 11600:arrhythmia 11595:Conduction 11351:Myocardium 11076:DiseasesDB 10745:2018-12-31 9618:15 January 8678:2013-08-23 7688:: 106595. 6975:health.gov 6797:Pediatrics 6253:: 756810. 6124:Tzoulaki I 5986:Pediatrics 5248:(2): 353. 5084:2017-06-01 5074:www.sbu.se 5042:2017-06-01 5032:www.sbu.se 4994:2016-06-07 4800:(1): 115. 4280:(Review). 4222:Pediatrics 3390:: 912047. 2882:(Review). 1933:References 1911:See also: 1685:Management 1655:arrhythmia 1597:vasoactive 1538:Medication 1418:See also: 1341:Replacing 1328:vegetarian 1310:Prevention 1284:biomarkers 1266:Screening 993:fibrinogen 987:(hs-CRP), 882:Untreated 770:See also: 626:lymphocyte 622:myocardium 350:, lack of 300:arrhythmia 227:Medication 196:Prevention 165:Arrhythmia 101:Chest pain 89:Cardiology 60:Micrograph 14905:Pneumonia 14893:childhood 14385:Infection 13933:Apex beat 13802:Diastolic 13370:Anti-Kell 13008:period / 13006:perinatal 12621:Phlebitis 12362:Trans fat 12298:Foam cell 12254:Arteritis 12221:(vessels) 12110:Pulmonary 11893:Pacemaker 11564:pulmonary 11545:tricuspid 11381:Alcoholic 10830:1473-6357 10702:1469-493X 10615:205176857 10558:254343574 10542:0735-1097 9848:1469-493X 9754:6 January 9398:: g4379. 9188:1469-493X 8278:1469-493X 8190:712123395 8079:: e8707. 7755:: g4490. 7712:0160-4120 7645:1469-493X 7360:: e3953. 7151:CC BY 4.0 6714:: g4164. 6577:2164/3181 6401:1932-6203 6331:2072-6643 6309:Nutrients 6269:2297-055X 6138:: i2416. 6103:cite book 6095:890409638 5883:196411135 5834:207538193 5638:Europe". 5275:24 August 4854:: 76–82. 3909:2097/6377 3658:265356623 3208:235073575 3192:0735-1097 2961:248155592 2494:1469-493X 2242:2072-6643 2220:Nutrients 1711:pacemaker 1691:Influenza 1651:Magnesium 1643:vitamin C 1639:vitamin E 1472:DASH diet 1380:Decrease 1262:Screening 1238:material) 1159:mutations 852:trans-fat 778:menopause 632:types of 210:Treating 207:Treatment 84:Specialty 74:(brown). 14935:Syphilis 14846:HIV/AIDS 14804:Dementia 14777:prostate 14772:lymphoma 14752:cervical 14722:Bed bugs 14256:thrombus 14193:Arterial 13785:Systolic 13758:Split S2 13340:Bleeding 13031:placenta 12835:Embolism 12437:Aneurysm 12374:Stenosis 12308:Atheroma 12259:Aortitis 12228:Arteries 11976:Asystole 11876:Familial 11570:stenosis 11551:stenosis 11532:stenosis 11513:stenosis 11508:prolapse 11230:Sequelae 11133:Ischemia 10971:13738641 10963:28054577 10928:28094270 10879:27905474 10789:16928278 10781:23489753 10739:Archived 10720:36398903 10607:25940444 10550:36480969 10501:22493407 10460:16935995 10419:12160191 10378:23265337 10337:20079494 10302:24217421 10261:51615818 10253:29991644 10212:23335472 10163:21575619 10114:28301692 10065:15674925 10016:24825181 10007:10075056 9964:22818936 9915:25120097 9866:34741536 9807:33704780 9748:archived 9712:19293072 9671:30894318 9612:Archived 9594:21742097 9570:Hiatt WR 9555:19655124 9506:24910232 9471:27849333 9422:25038074 9373:26099117 9330:4 August 9302:23440795 9250:22732744 9206:38533994 9197:10966941 9149:24243703 9140:10280688 9098:10730075 9090:14615107 9048:10374187 9040:20881867 9004:19951800 8996:25131978 8961:18480116 8912:33512717 8860:17449506 8811:Archived 8752:32677681 8721:17688420 8665:43795786 8657:21803192 8615:25519688 8566:29387889 8517:32114706 8468:30019869 8441:52013596 8433:24723079 8389:28620111 8345:26268692 8296:32827219 8237:43493760 8229:22583051 8155:31728492 8103:23386268 8054:27193606 8013:17324730 7972:16306540 7931:11451721 7890:11136953 7849:Archived 7845:21854893 7806:19378874 7779:25073782 7730:34011457 7663:36194420 7606:28290160 7557:26272648 7479:24745774 7420:16508562 7384:22777025 7335:24754972 7292:24856319 7243:35497445 7235:24169589 7193:45312858 7140:33933205 7045:26724178 7001:Archived 6979:Archived 6957:22336785 6938:14974003 6907:27838722 6866:16330680 6825:37741456 6817:17015535 6781:23782870 6773:19419257 6738:25011450 6689:26936862 6635:21343207 6611:: d671. 6586:24636546 6540:33555049 6491:45241607 6483:17030958 6419:30571724 6371:PLOS ONE 6349:34836208 6287:34805312 6206:37833889 6198:20425267 6162:27184143 6057:22510399 6016:22084329 5967:29998297 5926:26077254 5918:17057748 5875:17182988 5826:25775317 5791:22847227 5750:25223981 5709:29896632 5668:54227479 5660:10466661 5624:14975468 5583:17184858 5546:1 August 5521:23913203 5513:19965897 5478:36312234 5470:17001210 5435:23603848 5378:34482706 5329:28911261 5270:73477338 5262:30844346 5220:20298931 5171:18035211 5136:28088988 5036:Archived 4988:Archived 4966:24176435 4917:25911639 4868:27475981 4826:25154373 4775:19364974 4719:25271417 4679:PLOS ONE 4660:Archived 4621:21339319 4583:20585020 4531:22113148 4489:Archived 4458:21835944 4450:19770848 4407:10924297 4366:41892834 4358:23410608 4308:27647451 4252:29907703 4203:Archived 4172:30955975 4123:20338493 4074:28331015 4050:: j909. 4017:12135957 3976:24808490 3918:20338284 3873:18468872 3838:32827219 3789:Archived 3758:15213107 3712:7:43–54. 3699:37170819 3616:Archived 3573:16754702 3517:10069784 3416:25663838 3365:23218570 3311:27324359 3260:26343387 3200:34016265 3148:22424232 3029:30811593 3021:15364185 2953:35418240 2912:28932354 2858:23001745 2806:36437057 2798:22392596 2707:24573352 2658:Archived 2622:24074752 2571:24339983 2531:PLOS ONE 2512:34881426 2455:39752176 2447:27431356 2408:18316498 2364:27768852 2312:25785893 2260:34959857 2201:27733281 2149:25530442 2092:Archived 1999:23239837 1907:Research 1629:While a 1556:fibrates 1396:disease. 1155:leukemia 1132:asbestos 1099:dynamite 908:insomnia 789:Estrogen 732:Genetics 630:monocyte 352:exercise 312:carditis 220:diabetes 177:Diabetes 96:Symptoms 68:fibrosis 14925:Suicide 14888:Obesity 14861:Measles 14851:Leprosy 14792:ovarian 14787:stomach 14742:bladder 14690:Global 13895:doubled 13860:carotid 13579:rubella 13209:Chignon 13063:chorion 12656:abdomen 12337:Hyaline 11376:Dilated 11318:Chronic 11126:(heart) 11070:D002318 10919:5880294 10870:5525550 10733:Roo S. 10711:9673465 10598:8511741 10203:3548618 10188:: f10. 10154:5945285 10105:6464316 10056:6464851 9955:3645500 9906:6669260 9857:8571912 9798:8094925 9662:7685565 9514:5064731 9462:6464497 9413:4103514 9293:6481400 8952:2386598 8903:8092432 8851:1857760 8729:2248777 8606:6483405 8557:5885893 8508:7049091 8336:4532752 8287:8092457 8146:6855944 8094:4688426 7770:4115152 7721:8204267 7690:Bibcode 7654:9531722 7597:6464686 7548:6999125 7428:9125890 7375:3392078 7283:4126399 7185:8615707 7131:8102467 7089:14 June 7068:14 June 6729:4091648 6680:4783255 6626:3043109 6531:8093137 6461:Obesity 6410:6301673 6379:Bibcode 6340:8624676 6278:8604150 6153:4868251 6007:4536582 5426:5833942 5405:Bibcode 5369:8649542 5320:5933669 5211:3807611 5127:8045769 5068:(SBU). 4957:3815706 4908:4612342 4817:4283079 4766:2956982 4710:4182667 4687:Bibcode 4629:6420111 4574:2924678 4415:8747779 4299:5567876 4257:28 June 4243:6260972 4163:6497989 4114:3865979 4065:5594422 4025:1589727 3829:8092457 3622:May 23, 3612:NPR.org 3564:2563742 3407:4309297 3356:3819990 3302:6188655 3251:4589895 3139:3319439 3097:9386201 2903:5583538 2849:3483430 2698:4181359 2613:4781046 2562:3855368 2539:Bibcode 2503:8655103 2355:5291481 2303:4736723 2251:8706326 2192:5388903 2140:4340604 1990:5408511 1585:Aspirin 1547:Statins 1290:(ABI), 1087:arsenic 983:score, 863:Alcohol 807:Tobacco 724:of the 694:alcohol 387:aspirin 364:alcohol 356:obesity 344:smoking 232:Aspirin 189:alcohol 185:Smoking 109:fatigue 14930:Stroke 14841:Herpes 14747:breast 14737:Cancer 14717:Autism 14707:Asthma 14408:Cancer 14293:Venous 14163:J wave 14059:Other 13728:Angina 13154:Growth 13067:amnion 12056:J wave 11809:Atrial 11737:Atrial 11526:aortic 11502:mitral 11494:Valves 11440:valves 11292:Layers 11161:(SCAD) 10969:  10961:  10926:  10916:  10877:  10867:  10828:  10787:  10779:  10761:Lancet 10718:  10708:  10700:  10641:  10613:  10605:  10595:  10556:  10548:  10540:  10499:  10458:  10417:  10376:  10335:  10300:  10259:  10251:  10210:  10200:  10161:  10151:  10112:  10102:  10063:  10053:  10014:  10004:  9962:  9952:  9934:Lancet 9913:  9903:  9864:  9854:  9846:  9805:  9795:  9710:  9669:  9659:  9592:  9553:  9512:  9504:  9486:Lancet 9469:  9459:  9420:  9410:  9371:  9300:  9290:  9248:  9204:  9194:  9186:  9147:  9137:  9096:  9088:  9070:Lancet 9046:  9038:  9002:  8994:  8976:Lancet 8959:  8949:  8910:  8900:  8858:  8848:  8750:  8746:, 8727:  8719:  8663:  8655:  8637:Lancet 8613:  8603:  8564:  8554:  8515:  8505:  8466:  8439:  8431:  8397:367602 8395:  8387:  8343:  8333:  8294:  8284:  8276:  8235:  8227:  8188:  8178:  8153:  8143:  8101:  8091:  8052:  8011:  7970:  7929:  7888:  7843:  7804:  7777:  7767:  7728:  7718:  7710:  7661:  7651:  7643:  7604:  7594:  7555:  7545:  7477:  7426:  7418:  7382:  7372:  7333:  7290:  7280:  7241:  7233:  7191:  7183:  7138:  7128:  7110:Lancet 7043:  7023:Lancet 6955:  6951:, 6936:  6905:  6864:  6823:  6815:  6779:  6771:  6736:  6726:  6687:  6677:  6633:  6623:  6584:  6538:  6528:  6489:  6481:  6417:  6407:  6399:  6347:  6337:  6329:  6285:  6275:  6267:  6204:  6196:  6160:  6150:  6093:  6083:  6055:  6014:  6004:  5965:  5924:  5916:  5881:  5873:  5832:  5824:  5789:  5748:  5707:  5666:  5658:  5640:Lancet 5622:  5581:  5519:  5511:  5476:  5468:  5433:  5423:  5376:  5366:  5327:  5317:  5268:  5260:  5218:  5208:  5169:  5134:  5124:  4964:  4954:  4915:  4905:  4866:  4824:  4814:  4773:  4763:  4717:  4707:  4652:  4627:  4619:  4581:  4571:  4529:  4481:  4456:  4448:  4413:  4405:  4364:  4356:  4328:Lancet 4306:  4296:  4250:  4240:  4195:  4170:  4160:  4142:Lancet 4121:  4111:  4072:  4062:  4023:  4015:  3974:  3916:  3871:  3836:  3826:  3781:  3756:  3749:437139 3746:  3697:  3656:  3571:  3561:  3515:  3459:  3414:  3404:  3363:  3353:  3309:  3299:  3258:  3248:  3206:  3198:  3190:  3146:  3136:  3095:  3058:  3027:  3019:  2991:Lancet 2959:  2951:  2910:  2900:  2856:  2846:  2804:  2796:  2753:  2705:  2695:  2650:  2620:  2610:  2569:  2559:  2510:  2500:  2492:  2453:  2445:  2427:Lancet 2406:  2362:  2352:  2310:  2300:  2258:  2248:  2240:  2199:  2189:  2171:Lancet 2147:  2137:  2119:Lancet 2084:  1997:  1987:  1882:  1876:  1870:  1864:  1858:  1852:  1846:  1840:  1834:  1828:  1822:  1816:  1810:  1794:  1788:  1782:  1776:  1770:  1764:  1758:  1752:  1746:  1740:  1717:and a 1671:review 1647:Niacin 1552:Niacin 1426:, and 1363:Statin 1278:, and 1143:stroke 1058:stroke 843:, and 533:stroke 500:  494:  488:  482:  476:  470:  464:  458:  452:  446:  440:  434:  428:  326:, and 276:angina 274:(e.g. 246:Deaths 191:intake 145:stroke 14876:child 14767:liver 14131:Other 13969:Shock 13921:Other 13872:Pulse 13855:Bruit 13627:Other 13451:Ileus 13198:scalp 12771:Other 12604:Veins 12454:torso 12396:Other 12143:Other 12127:Right 12105:Right 11719:sinus 11668:Right 11418:Viral 11313:Acute 11267:weeks 11238:hours 11150:(CAD) 11081:28808 11059:429.2 11044:I51.6 10967:S2CID 10785:S2CID 10611:S2CID 10554:S2CID 10257:S2CID 9982:(PDF) 9510:S2CID 9268:(PDF) 9094:S2CID 9044:S2CID 9000:S2CID 8763:with 8725:S2CID 8697:(PDF) 8672:(PDF) 8661:S2CID 8633:(PDF) 8437:S2CID 8393:S2CID 8233:S2CID 7523:(PDF) 7424:S2CID 7239:S2CID 7211:(PDF) 7189:S2CID 6821:S2CID 6777:S2CID 6487:S2CID 6202:S2CID 5922:S2CID 5879:S2CID 5830:S2CID 5664:S2CID 5517:S2CID 5474:S2CID 5266:S2CID 4625:S2CID 4601:Heart 4454:S2CID 4411:S2CID 4362:S2CID 4021:S2CID 3654:S2CID 3226:(PDF) 3204:S2CID 3025:S2CID 2957:S2CID 2802:S2CID 2451:S2CID 2095:(PDF) 2078:(PDF) 1480:fiber 1434:death 1332:vegan 894:Sleep 718:sleep 413:Types 368:sleep 264:heart 137:Types 66:with 64:heart 62:of a 14782:skin 13385:Rh E 13380:Rh D 13375:Rh c 12705:head 12235:and 12122:Left 12100:Left 11717:and 11673:Left 11255:days 11065:MeSH 11054:9-CM 10959:PMID 10924:PMID 10875:PMID 10826:ISSN 10777:PMID 10716:PMID 10698:ISSN 10686:2022 10639:ISBN 10603:PMID 10581:2015 10546:PMID 10538:ISSN 10497:PMID 10456:PMID 10415:PMID 10374:PMID 10333:PMID 10298:PMID 10249:PMID 10208:PMID 10159:PMID 10110:PMID 10088:2017 10061:PMID 10039:2005 10012:PMID 9990:2014 9960:PMID 9911:PMID 9889:2014 9862:PMID 9844:ISSN 9830:2021 9803:PMID 9756:2013 9708:PMID 9667:PMID 9620:2015 9590:PMID 9551:PMID 9502:PMID 9467:PMID 9418:PMID 9369:PMID 9332:2018 9298:PMID 9246:PMID 9202:PMID 9184:ISSN 9145:PMID 9086:PMID 9036:PMID 8992:PMID 8957:PMID 8908:PMID 8856:PMID 8748:PMID 8717:PMID 8653:PMID 8611:PMID 8589:2014 8562:PMID 8513:PMID 8491:2020 8464:PMID 8429:PMID 8385:PMID 8341:PMID 8292:PMID 8274:ISSN 8260:2020 8225:PMID 8186:OCLC 8176:ISBN 8151:PMID 8099:PMID 8050:PMID 8009:PMID 7968:PMID 7927:PMID 7886:PMID 7841:PMID 7802:PMID 7775:PMID 7726:PMID 7708:ISSN 7659:PMID 7641:ISSN 7629:2022 7602:PMID 7553:PMID 7531:2015 7475:PMID 7416:PMID 7380:PMID 7331:PMID 7288:PMID 7231:PMID 7181:PMID 7136:PMID 7091:2021 7070:2021 7041:PMID 6953:PMID 6934:PMID 6903:PMID 6885:JAMA 6862:PMID 6813:PMID 6769:PMID 6734:PMID 6685:PMID 6631:PMID 6582:PMID 6536:PMID 6514:2021 6479:PMID 6415:PMID 6397:ISSN 6345:PMID 6327:ISSN 6283:PMID 6265:ISSN 6194:PMID 6158:PMID 6109:link 6091:OCLC 6081:ISBN 6053:PMID 6012:PMID 5963:PMID 5945:JAMA 5914:PMID 5871:PMID 5822:PMID 5787:PMID 5746:PMID 5705:PMID 5687:JAMA 5656:PMID 5620:PMID 5579:PMID 5548:2011 5509:PMID 5466:PMID 5431:PMID 5374:PMID 5325:PMID 5277:2023 5258:PMID 5216:PMID 5167:PMID 5132:PMID 4962:PMID 4913:PMID 4864:PMID 4822:PMID 4771:PMID 4715:PMID 4650:ISBN 4617:PMID 4579:PMID 4527:PMID 4479:ISBN 4446:PMID 4403:PMID 4354:PMID 4304:PMID 4259:2021 4248:PMID 4193:ISBN 4168:PMID 4119:PMID 4070:PMID 4013:PMID 3972:PMID 3914:PMID 3869:PMID 3834:PMID 3812:2020 3779:ISBN 3754:PMID 3695:PMID 3624:2014 3569:PMID 3513:PMID 3457:ISBN 3412:PMID 3388:2015 3361:PMID 3307:PMID 3256:PMID 3196:PMID 3188:ISSN 3144:PMID 3116:Cell 3093:PMID 3056:ISBN 3017:PMID 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