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Herpes

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1345:(also known as disseminated shingles). The original compounds used were 5-iodo-2'-deoxyuridine, AKA idoxuridine, IUdR, or(IDU) and 1-β-D-arabinofuranosylcytosine or ara-C, later marketed under the name cytosar or cytarabine. The usage expanded to include topical treatment of herpes simplex, zoster, and varicella. Some trials combined different antivirals with differing results. The introduction of 9-β-D-arabinofuranosyladenine, (ara-A or vidarabine), considerably less toxic than ara-C, in the mid-1970s, heralded the way for the beginning of regular neonatal antiviral treatment. Vidarabine was the first systemically administered antiviral medication with activity against HSV for which therapeutic efficacy outweighed toxicity for the management of life-threatening HSV disease. Intravenous vidarabine was licensed for use by the 1039:
3% if the infection is recurrent, and is 1–3% if the woman is seropositive for both HSV-1 and HSV-2, and is less than 1% if no lesions are visible. Women seropositive for only one type of HSV are only half as likely to transmit HSV as infected seronegative mothers. To prevent neonatal infections, seronegative women are recommended to avoid unprotected oral-genital contact with an HSV-1-seropositive partner and conventional sex with a partner having a genital infection during the last trimester of pregnancy. Mothers infected with HSV are advised to avoid procedures that would cause trauma to the infant during birth (e.g. fetal scalp electrodes, forceps, and vacuum extractors) and, should lesions be present, to elect
1399:. During the 1970s, there was an increase in sexually transmitted diseases. One of the diseases that increased dramatically was genital herpes. In response, ASHA created the National Herpes Resource Center in 1979. The Herpes Resource Center (HRC) was designed to meet the growing need for education and awareness about the virus. One of the projects of the HRC was to create a network of local support (HELP) groups. The goal of these HELP groups was to provide a safe, confidential environment where participants can get accurate information and share experiences, fears, and feelings with others who are concerned about herpes. 1350:
notch and led to vidarabine vs. aciclovir trials in the late 1980s. The lower toxicity and ease of administration over vidarabine has led to aciclovir becoming the drug of choice for herpes treatment after it was licensed by the FDA in 1998. Another advantage in the treatment of neonatal herpes included greater reductions in mortality and morbidity with increased dosages, which did not occur when compared with increased dosages of vidarabine. However, aciclovir seems to inhibit antibody response, and newborns on aciclovir antiviral treatment experienced a slower rise in antibody titer than those on vidarabine.
1226:), itching, and pain where lumbosacral nerves innervate the skin. Prodrome may occur as long as several days or as short as a few hours before lesions develop. Beginning antiviral treatment when prodrome is experienced can reduce the appearance and duration of lesions in some individuals. During recurrence, fewer lesions are likely to develop and are less painful and heal faster (within 5–10 days without antiviral treatment) than those occurring during the primary infection. Subsequent outbreaks tend to be periodic or episodic, occurring on average four or five times a year when not using antiviral therapy. 802:
symptoms may still shed and transmit viruses through their skin; asymptomatic shedding may represent the most common form of HSV-2 transmission. Asymptomatic shedding is more frequent within the first 12 months of acquiring HSV. Concurrent infection with HIV increases the frequency and duration of asymptomatic shedding. Some individuals may have much lower patterns of shedding, but evidence supporting this is not fully verified; no significant differences are seen in the frequency of asymptomatic shedding when comparing persons with one to 12 annual recurrences to those with no recurrences.
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buttocks, or upper thighs, areas that may come in contact with ulcers or genital secretions during sexual activity. Protection against herpes simplex depends on the site of the ulcer; therefore, if ulcers appear on areas not covered by condoms, abstaining from sexual activity until the ulcers are fully healed is one way to limit risk of transmission. The risk is not eliminated, however, as viral shedding capable of transmitting infection may still occur while the infected partner is asymptomatic. The use of condoms or
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exposure of mucosal tissue to potential infection sites. Transmission risk from infected female to male is around 4–5% annually. Suppressive antiviral therapy reduces these risks by 50%. Antivirals also help prevent the development of symptomatic HSV in infection scenarios, meaning the infected partner will be seropositive but symptom-free by about 50%. Condom use also reduces the transmission risk significantly. Condom use is much more effective at preventing male-to-female transmission than
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original site of the infection or in proximity to nerve endings that reach out from the infected ganglia. In the case of a genital infection, sores can appear at the original site of infection or near the base of the spine, the buttocks, or the back of the thighs. HSV-2-infected individuals are at higher risk for acquiring HIV when practicing unprotected sex with HIV-positive persons, in particular during an outbreak with active lesions.
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contracted through direct skin-to-skin contact with an infected individual, but can also be contracted by exposure to infected saliva, semen, vaginal fluid, or the fluid from herpetic blisters. To infect a new individual, HSV travels through tiny breaks in the skin or mucous membranes in the mouth or genital areas. Even microscopic abrasions on mucous membranes are sufficient to allow viral entry.
10883: 722:—is unknown, it may be related to the reactivation of HSV-1. This theory has been contested, however, since HSV is detected in large numbers of individuals having never experienced facial paralysis, and higher levels of antibodies for HSV are not found in HSV-infected individuals with Bell's palsy compared to those without. Antivirals may improve the condition slightly when used together with 10871: 499: 1256:
role in the frequency of cold sore outbreaks. An area of human chromosome 21 that includes six genes has been linked to frequent oral herpes outbreaks. An immunity to the virus is built over time. Most infected individuals experience fewer outbreaks and outbreak symptoms often become less severe. After several years, some people become perpetually
409:), or invades the central nervous system, damaging the brain (herpes encephalitis). People with immature or suppressed immune systems, such as newborns, transplant recipients, or people with AIDS, are prone to severe complications from HSV infections. HSV infection has also been associated with cognitive deficits of 1255:
The frequency and severity of recurrent outbreaks vary greatly between people. Some individuals' outbreaks can be quite debilitating, with large, painful lesions persisting for several weeks, while others experience only minor itching or burning for a few days. Some evidence indicates genetics play a
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Herpes is contracted through direct contact with an active lesion or body fluid of an infected person. Herpes transmission occurs between discordant partners; a person with a history of infection (HSV seropositive) can pass the virus to an HSV seronegative person. Herpes simplex virus 2 is typically
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Worldwide rates of either HSV-1 or HSV-2 are between 60% and 95% in adults. HSV-1 is usually acquired during childhood. Since there is no cure for either HSV-1 or HSV-2, rates of both inherently increase as people age. Rates of HSV-1 are between 70% and 80% in populations of low socioeconomic status
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have been formed in the United States and the United Kingdom, providing information about herpes and running message forums and dating websites for affected people. People with the herpes virus are often hesitant to divulge to other people, including friends and family, that they are infected. This
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Worldwide rates of either HSV-1 and/or HSV-2 are between 60 and 95% in adults. HSV-1 is more common than HSV-2, with rates of both increasing as people age. HSV-1 rates are between 70% and 80% in populations of low socioeconomic status and 40% to 60% in populations of improved socioeconomic status.
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The risk of transmission from mother to baby is highest if the mother becomes infected around the time of delivery (30% to 60%), since insufficient time will have occurred for the generation and transfer of protective maternal antibodies before the birth of the child. In contrast, the risk falls to
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occurs at some time in most individuals infected with herpes. It can occur more than a week before or after a symptomatic recurrence in 50% of cases. Virus enters into susceptible cells by entry receptors such as nectin-1, HVEM and 3-O sulfated heparan sulfate. Infected people who show no visible
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in 1977. Other experimental antivirals of that period included: heparin, trifluorothymidine (TFT), Ribivarin, interferon, Virazole, and 5-methoxymethyl-2'-deoxyuridine (MMUdR). The introduction of 9-(2-hydroxyethoxymethyl)guanine, AKA aciclovir, in the late 1970s raised antiviral treatment another
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The annual incidence in Canada of genital herpes due to HSV-1 and HSV-2 infection is not known (for a review of HSV-1/HSV-2 prevalence and incidence studies worldwide, see Smith and Robinson 2002). As many as one in seven Canadians aged 14 to 59 may be infected with herpes simplex type 2 virus and
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There are two types of herpes simplex virus, type 1 (HSV-1) and type 2 (HSV-2). HSV-1 more commonly causes infections around the mouth while HSV-2 more commonly causes genital infections. They are transmitted by direct contact with body fluids or lesions of an infected individual. Transmission may
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can provide greater protection than the male condom, as it covers the labia. The virus cannot pass through a synthetic condom, but a male condom's effectiveness is limited because herpes ulcers may appear on areas not covered by it. Neither type of condom prevents contact with the scrotum, anus,
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As with almost all sexually transmitted infections, women are more susceptible to acquiring genital HSV-2 than men. On an annual basis, without the use of antivirals or condoms, the transmission risk of HSV-2 from infected male to female is about 8–11%. This is believed to be due to the increased
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tests for antibodies to HSV were rarely useful to diagnosis and not routinely used in clinical practice. The older IgM serologic assay could not differentiate between antibodies generated in response to HSV-1 or HSV-2 infection. However, a glycoprotein G-specific (IgG) HSV test introduced in the
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However, asymptomatic carriers of the HSV-2 virus are still contagious. In many infections, the first symptom people will have of their own infections is the horizontal transmission to a sexual partner or the vertical transmission of neonatal herpes to a newborn at term. Since most asymptomatic
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Primary orofacial herpes is readily identified by examination of persons with no previous history of lesions and contact with an individual with known HSV infection. The appearance and distribution of sores is typically presents as multiple, round, superficial oral ulcers, accompanied by acute
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and no longer experience outbreaks, though they may still be contagious to others. Immunocompromised individuals may experience longer, more frequent, and more severe episodes. Antiviral medication has been proven to shorten the frequency and duration of outbreaks. Outbreaks may occur at the
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couple, a seronegative female runs a greater than 30% per year risk of contracting an HSV infection from a seropositive male partner. If an oral HSV-1 infection is contracted first, seroconversion will have occurred after 6 weeks to provide protective antibodies against a future genital HSV-1
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and 40% to 60% in populations of improved socioeconomic status. An estimated 536 million people worldwide (16% of the population) were infected with HSV-2 as of 2003 with greater rates among women and those in the developing world. Most people with HSV-2 do not realize that they are infected.
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mRNA-1608. Unsuccessful clinical trials have been conducted for some glycoprotein subunit vaccines. As of 2017, the future pipeline includes several promising replication-incompetent vaccine proposals while two replication-competent (live-attenuated) HSV vaccine are undergoing human testing.
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to reduce exposure of the child to infected secretions in the birth canal. The use of antiviral treatments, such as aciclovir, given from the 36th week of pregnancy, limits HSV recurrence and shedding during childbirth, thereby reducing the need for caesarean section.
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Xu, Fujie; Fujie Xu; Maya R. Sternberg; Benny J. Kottiri; Geraldine M. McQuillan; Francis K. Lee; Andre J. Nahmias; Stuart M. Berman; Lauri E. Markowitz (2006-10-23). "Trends in Herpes Simplex Virus Type 1 and Type 2 Seroprevalence in the United States".
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after an oral infection helps prevent additional HSV-1 infections such as whitlow, genital herpes, and herpes of the eye. Prior HSV-1 seroconversion seems to reduce the symptoms of a later HSV-2 infection, although HSV-2 can still be contracted.
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of HSV-1 or -2 from mother to newborn. During immunodeficiency, herpes simplex can cause unusual lesions in the skin. One of the most striking is the appearance of clean linear erosions in skin creases, with the appearance of a knife cut.
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Chen, Fangman; Xu, Hao; Liu, Jinli; Cui, Yuan; Luo, Xiaobo; Zhou, Yu; Chen, Qianming; Jiang, Lu (2017). "Efficacy and safety of nucleoside antiviral drugs for treatment of recurrent herpes labialis: a systematic review and meta-analysis".
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more than 90 per cent of them may be unaware of their status, a new study suggests. In the United States, it is estimated that about 1,640,000 HSV-2 seroconversions occur yearly (730,000 men and 910,000 women, or 8.4 per 1,000 persons).
1291:, 58% of the population is infected with HSV-1 and 16% are infected with HSV-2. Among those HSV-2-seropositive, only 19% were aware they were infected. During 2005–2008, the prevalence of HSV-2 was 39% in black people and 21% in women. 1047:
Aciclovir is the recommended antiviral for herpes suppressive therapy during the last months of pregnancy. The use of valaciclovir and famciclovir, while potentially improving compliance, have less-well-determined safety in pregnancy.
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Myśliwska J, Trzonkowski P, Bryl E, Lukaszuk K, Myśliwski A (2000). "Lower interleukin-2 and higher serum tumor necrosis factor-a levels are associated with perimenstrual, recurrent, facial herpes simplex infection in young women".
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Rotermann, Michelle; Langlois, Kellie A.; Severini, Alberto; Totten, Stephanie (2013-04-01). "Prevalence of Chlamydia trachomatis and herpes simplex virus type 2: Results from the 2009 to 2011 Canadian Health Measures Survey".
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Antivirals may reduce asymptomatic shedding; asymptomatic genital HSV-2 viral shedding is believed to occur on 20% of days per year in patients not undergoing antiviral treatment, versus 10% of days while on antiviral therapy.
852:. Adults with atypical presentation are more difficult to diagnose. Prodromal symptoms that occur before the appearance of herpetic lesions help differentiate HSV symptoms from the similar symptoms of other disorders, such as 1276:
An estimated 536 million people or 16% of the population worldwide were infected with HSV-2 as of 2003 with greater rates among women and in those in the developing world. Rates of infection are determined by the presence of
436:. As a result of primary infection, the body produces antibodies to the particular type of HSV involved, which can help reduce the odds of subsequent infection of that type at a different site. In HSV-1-infected individuals, 564:, scrumpox, wrestler's herpes, or mat herpes, which presents as skin ulceration on the face, ears, and neck. Symptoms include fever, headache, sore throat, and swollen glands. It occasionally affects the eyes or eyelids. 977:. Previous HSV-1 infection may reduce the risk for acquisition of HSV-2 infection among women by a factor of three, although the one study that states this has a small sample size of 14 transmissions out of 214 couples. 1298:
In British Columbia in 1999, the seroprevalence of HSV-2 antibody in leftover serum submitted for antenatal testing revealed a prevalence of 17%, ranging from 7% in women 15–19 years old to 28% in those 40–44 years.
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Allen LB, Hintz OJ, Wolf SM, et al. (June 1976). "Effect of 9-beta-D-arabinofuranosylhypoxanthine 5'-monophosphate on genital lesions and encephalitis induced by Herpesvirus hominis type 2 in female mice".
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Genital herpes can be more difficult to diagnose than oral herpes, since most people have none of the classical symptoms. Further confusing diagnosis, several other conditions resemble genital herpes, including
742:-epsilon4 allele carriers), HSV-1 appears to be particularly damaging to the nervous system and increases one's risk of developing Alzheimer's disease. The virus interacts with the components and receptors of 6244:
ASHA was founded in 1914 in New York City, formed out of early 20th-century social reform movements focused on fighting sexually transmitted infections (known then as venereal disease, or VD) and prostitution.
1411:) was started in 1982, becoming a registered charity with a Department of Health grant in 1985. The charity started as a string of local group meetings before acquiring an office and a national spread. 6570: 3380:
Wald A, Langenberg AG, Link K, Izu AE, Ashley R, Warren T, Tyring S, Douglas JM Jr, Corey L (2001). "Effect of condoms on reducing the transmission of herpes simplex virus type 2 from men to women".
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to test for presence of viral DNA. Although these procedures produce highly sensitive and specific diagnoses, their high costs and time constraints discourage their regular use in clinical practice.
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Commonly referred to as cold sores or fever blisters, herpes labialis is the most common presentation of recurrent HSV-1 infection following the re-emergence of the virus from the trigeminal nerve.
5656:"Target-Organ Treatment of Neurotropic Virus Diseases: Efficacy as a Chemotherapy Tool and Comparison of Activity of Adenine Arabinoside, Cytosine Arabinoside, Idoxuridine, and Trifluorothymidine" 6371: 1326:, blisters "o'er ladies' lips" are mentioned. In the 18th century, it was so common among prostitutes that it was called "a vocational disease of women". The term 'herpes simplex' appeared in 2415:
Jocelyn A. Lieb; Stacey Brisman; Sara Herman; Jennifer MacGregor; Marc E. Grossman (2008). "Linear erosive Herpes Simplex Virus infection in immunocompromised patients: the "Knife-Cut Sign"".
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which arose from the work of the American Sexual Health Association (ASHA). The ASHA was created in 1914 in response to the increase in sexually transmitted diseases that had spread during
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Condoms offer moderate protection against HSV-2 in both men and women, with consistent condom users having a 30%-lower risk of HSV-2 acquisition compared with those who never use condoms. A
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Herpetic gingivostomatitis is often the initial presentation during the first herpes infection. It is of greater severity than herpes labialis, which is often the subsequent presentation.
602:. Despite its low incidence, HSE is the most common sporadic fatal encephalitis worldwide. HSV-2 is the most common cause of Mollaret's meningitis, a type of recurrent viral meningitis. 5811:
Sidwell RW, Huffman JH, Khare GP, Allen LB, Witkowski JT, Robins RK (August 1972). "Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide".
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Ch'ien LT, Whitley RJ, Alford CA, Galasso GJ (June 1976). "Adenine arabinoside for therapy of herpes zoster in immunosuppressed patients: preliminary results of a collaborative study".
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Glenny AM, Fernandez Mauleffinch LM, Pavitt S, Walsh T (January 2009). "Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer".
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Herpes cycles between periods of active disease followed by periods without symptoms. The first episode is often more severe and may be associated with fever, muscle pains, swollen
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Oakley C, Epstein JB, Sherlock CH (1997). "Reactivation of oral herpes simplex virus: implications for clinical management of herpes simplex virus recurrence during radiotherapy".
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Herpes whitlow is a painful infection that typically affects the fingers or thumbs. On occasion, infection occurs on the toes or the nail cuticle. Individuals who participate in
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Elad S, Zadik Y, Hewson I, et al. (August 2010). "A systematic review of viral infections associated with oral involvement in cancer patients: a spotlight on Herpesviridea".
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Some people experience negative feelings related to the condition following diagnosis, in particular, if they have acquired the genital form of the disease. Feelings can include
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Herpes simplex encephalitis (HSE) is a rare life-threatening condition that is thought to be caused by the transmission of HSV-1 either from the nasal cavity to the brain's
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Kaminester LH, Pariser RJ, Pariser DM, et al. (December 1999). "A double-blind, placebo-controlled study of topical tetracaine in the treatment of herpes labialis".
5039: 3211:"Comparison of Western blot (immunoblot) and glycoprotein G-specific immunodot enzyme assay for detecting antibodies to herpes simplex virus types 1 and 2 in human sera" 2086:
Dickerson FB, Boronow JJ, Stallings C, et al. (March 2004). "Infection with herpes simplex virus type 1 is associated with cognitive deficits in bipolar disorder".
9956: 6556: 5487:"Susceptibility of Herpesviruses to Cytosine Arabinoside: Standardization of Susceptibility Test Procedure and Relative Resistance of Herpes Simplex Type 2 Strains" 2808: 6125: 1241:
or other febrile diseases, can cause outbreaks. Reactivation due to other infections is the likely source of the historic terms 'cold sore' and 'fever blister'.
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Nasser M, Fedorowicz Z, Khoshnevisan MH, Shahiri Tabarestani M (October 2008). Nasser M (ed.). "Acyclovir for treating primary herpetic gingivostomatitis".
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Shukla, Deepak; Liu, Jian; Blaiklock, Peter; Shworak, Nicholas W.; Bai, Xiaomei; Esko, Jeffrey D.; Cohen, Gary H.; Eisenberg, Roselyn; et al. (1999).
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O'Meara A, Deasy PF, Hillary IB, Bridgen WD (December 1979). "Acyclovir for treatment of mucocutaneous herpes infection in a child with leukaemia".
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Chambers A, Perry M (2008). "Salivary mediated autoinoculation of herpes simplex virus on the face in the absence of "cold sores," after trauma".
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Fatahzadeh M, Schwartz RA (2007). "Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management".
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In a 2007 study, 1,900 people (25% of which had herpes) ranked genital herpes second for social stigma, out of all sexually transmitted diseases (
321:, stress, and sunlight exposure. Oral and genital herpes is usually diagnosed based on the presenting symptoms. The diagnosis may be confirmed by 4677:
Rooney JF, Straus SE, Mannix ML, et al. (1992). "UV light-induced reactivation of herpes simplex virus type 2 and prevention by acyclovir".
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Perfect MM, Bourne N, Ebel C, Rosenthal SL (October 2005). "Use of complementary and alternative medicine for the treatment of genital herpes".
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Pyles RB (2001). "The association of herpes simplex virus and Alzheimer's disease: a potential synthesis of genetic and environmental factors".
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Whitley, R. J.; Soong, S. J.; Linneman, C.; Liu, C.; Pazin, G.; Alford, C. A. (1982-01-15). "Herpes simplex encephalitis. Clinical Assessment".
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Herpes originated and evolved in Africa and could be the result of a cross-species transmission event from gibbons, orangutans, or gorillas.
5864:"Comparison of the Antiviral Effects of 5-Methoxymethyl-deoxyuridine with 5-Iododeoxyuridine, Cytosine Arabinoside, and Adenine Arabinoside" 1056:
No method eradicates herpes virus from the body, but antiviral medications can reduce the frequency, duration, and severity of outbreaks.
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Antibodies that develop following an initial infection with a type of HSV can reduce the odds of reinfection with the same virus type. In a
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Gagyor, Ildiko; Madhok, Vishnu B.; Daly, Fergus; Somasundara, Dhruvashree; Sullivan, Michael; Gammie, Fiona; Sullivan, Frank (2015-11-09).
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Esiri, M. M. (May 1982). "Herpes simplex encephalitis. An immunohistological study of the distribution of viral antigen within the brain".
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Wald A, Langenberg AG, Krantz E, et al. (November 2005). "The relationship between condom use and herpes simplex virus acquisition".
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Herpes antiviral therapy began in the early 1960s with the experimental use of medications that interfered with viral replication called
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Evidence supports the use of aciclovir and valaciclovir in the treatment of herpes labialis as well as herpes infections in people with
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Segal AL, Katcher AH, Brightman VJ, Miller MF (1974). "Recurrent herpes labialis, recurrent aphthous ulcers, and the menstrual cycle".
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Mertz, GJ; Benedetti J; Ashley R; Selke SA; Corey L. (1 February 1992). "Risk factors for the sexual transmission of genital herpes".
1183:, lemon balm, topical zinc, or licorice root cream in treatment, these preliminary studies have not been confirmed by higher-quality 444:
Many people infected with HSV-2 display no physical symptoms—individuals with no symptoms are described as asymptomatic or as having
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In Nova Scotia, 58% of 1,790 HSV isolates from genital lesion cultures in women were HSV-1; in men, 37% of 468 isolates were HSV-1.
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Holmes C, Cotterell D (December 2009). "Role of infection in the pathogenesis of Alzheimer's disease: implications for treatment".
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in 1713, where the terms 'herpes miliaris' and 'herpes exedens' also appeared. Herpes was not found to be a virus until the 1940s.
6278: 401:. Common infection of the skin or mucosa may affect the face and mouth (orofacial herpes), genitalia (genital herpes), or hands ( 10844: 10042: 9993: 7370: 6231: 6151: 1229:
The causes of reactivation are uncertain, but several potential triggers have been documented. A 2009 study showed the protein
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Allen LB, Wolf SM, Hintz CJ, Huffman JH, Sidwell RW (March 1977). "Effect of ribavirin on Type 2 Herpesvirus hominis (HVH/2)
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Leung DT, Sacks SL (October 2003). "Current treatment options to prevent perinatal transmission of herpes simplex virus".
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of the nervous system. The double-stranded DNA of the virus is incorporated into the cell physiology by infection of the
348:(acetaminophen) and topical lidocaine may be used to help with the symptoms. Treatments with antiviral medication such as 10527: 10370: 8016: 6129: 2812: 9644: 9128: 7152: 1230: 6396: 6002:"Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections" 3800:"Effect of serologic status and cesarean delivery on transmission rates of herpes simplex virus from mother to infant" 10771: 9404: 7053: 1746: 1346: 1238: 988:, when used topically in a microbicidal vaginal gel, was reported to reduce herpes virus sexual transmission by 51%. 3289:"Identification of women at unsuspected risk of primary infection with herpes simplex virus type 2 during pregnancy" 10746: 10683: 10678: 10560: 9988: 9968: 8880: 8218: 7162: 6001: 4747:
Ichihashi M, Nagai H, Matsunaga K (2004). "Sunlight is an important causative factor of recurrent herpes simplex".
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Chon T, Nguyen L, Elliott TC (July 2007). "Clinical inquiries. What are the best treatments for herpes labialis?".
1013:. When one partner has a herpes simplex infection and the other does not, the use of antiviral medication, such as 381:, which is related to the meaning 'to creep', referring to spreading blisters. The name does not refer to latency. 268:
in groups, often called cold sores or fever blisters, or may just cause a sore throat. Genital herpes involves the
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When symptomatic, the typical manifestation of a primary HSV-1 or HSV-2 genital infection is clusters of inflamed
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have not approved a vaccine for herpes. However, there are herpes vaccines currently in clinical trials, such as
1017:, in conjunction with a condom, further decreases the chances of transmission to the uninfected partner. Topical 276:. These typically heal over two to four weeks. Tingling or shooting pains may occur before the blisters appear. 428:. Following a primary infection, the virus enters the nerves at the site of primary infection, migrates to the 249:. Herpes infections are categorized by the area of the body that is infected. The two major types of herpes are 10577: 10412: 8555: 7660: 7121: 6747: 1320:
is said to have banned kissing in Rome for a time due to so many people having cold sores. In the 16th century
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testing is often used to confirm a diagnosis of genital herpes. Laboratory tests include culture of the virus,
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In Norway, a study published in 2000 found that up to 70–90% of genital initial infections were due to HSV-1.
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The most effective method of avoiding genital infections is by avoiding vaginal, oral, manual, and anal sex.
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Wertheim, Joel O.; Smith, Martin D.; Smith, Davey M.; Scheffler, Konrad; Kosakovsky Pond, Sergei L. (2014).
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Leone P (2005). "Reducing the risk of transmitting genital herpes: advances in understanding and therapy".
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Itzhaki RF, Wozniak MA (May 2008). "Herpes simplex virus type 1 in Alzheimer's disease: the enemy within".
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Nilsen A, Myrmel H (2000). "Changing trends in genital herpes simplex virus infection in Bergen, Norway".
10469: 10432: 10162: 9443: 9355: 8828: 8719: 8464: 8198: 8008: 7955: 7909: 7231: 6762: 6717: 4931:"Seroprevalence of Herpes Simplex Virus Type 2 Among Persons Aged 14–49 Years – United States, 2005–2008" 2540:
Linder T, Bossart W, Bodmer D (January 2005). "Bell's palsy and Herpes simplex virus: fact or mystery?".
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Balasubramaniam, R; Kuperstein, AS; Stoopler, ET (April 2014). "Update on oral herpes virus infections".
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Armstrong GL, Schillinger J, Markowitz L, Nahmias AJ, Johnson RE, McQuillan GM, St Louis ME (May 2001).
2266:"The olfactory nerve: a shortcut for influenza and other viral diseases into the central nervous system" 1710: 1211:. HSV latency is static; no virus is produced; and is controlled by a number of viral genes, including 1021:
that contain chemicals that directly inactivate the virus and block viral entry are being investigated.
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Green, J; Ferrier, S; Kocsis, A; Shadrick, J; Ukoumunne, OC; Murphy, S; Hetherton, J (February 2003).
5335:"Cytosine Arabinoside Therapy for Herpes Simplex Encephalitis – Clinical Experience with Six Patients" 5040:"Herpes virus has infected nearly one in five Canadians over age 35, most unaware they have it: study" 4087:
Handbook of pediatric hematology and oncology : Children's Hospital & Research Center Oakland
1005:
also limits the transmission of herpes from the genitals of one partner to the mouth of the other (or
309:. It may be spread to an infant during childbirth. After infection, the viruses are transported along 10484: 10202: 10106: 9577: 9041: 8833: 8419: 7997: 7644: 7506: 4317:
Treister NS, Woo SB (April 2010). "Topical n-docosanol for management of recurrent herpes labialis".
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Martin ET, Krantz E, Gottlieb SL, Magaret AS, Langenberg A, Stanberry L, Kamb M, Wald A (July 2009).
3544:"Topical Tenofovir, a Microbicide Effective against HIV, Inhibits Herpes Simplex Virus-2 Replication" 1842:
Steiner, I; Benninger, F (December 2013). "Update on herpes virus infections of the nervous system".
915: 193: 6548: 6296: 5446:"Cytosine arabinoside therapy for disseminated herpes zoster in a patient with IgG pyroglobulinemia" 1885:
Stephenson-Famy, A; Gardella, C (December 2014). "Herpes Simplex Virus Infection During Pregnancy".
10791: 10570: 10555: 10251: 10207: 10152: 10025: 9983: 9751: 9597: 8639: 8525: 8111: 7693: 7349: 6995: 6932: 6827: 6496: 5316: 3527:
Topical Tenofovir, a Microbicide Effective against HIV, Inhibits Herpes Simplex Virus-2 Replication
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study of the herpes simplex type 1 virus confirmed the human migration pattern theory known as the
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Other identified triggers include local injury to the face, lips, eyes, or mouth; trauma; surgery;
961: 578: 294: 290: 10624: 2584: 859:. When lesions do not appear inside the mouth, primary orofacial herpes is sometimes mistaken for 827:
Herpes simplex virus is divided into two types. However, each may cause infections in all areas.
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Handsfield HH (2000). "Public Health Strategies to Prevent Genital Herpes: Where Do We Stand?".
1131:. The evidence to support the use of aciclovir in primary herpetic gingivostomatitis is weaker. 981:
individuals are unaware of their infection, they are considered at high risk for spreading HSV.
10834: 10801: 10474: 10464: 10459: 10401: 10328: 10284: 10180: 10175: 9961: 9791: 9786: 9761: 9607: 9538: 9365: 9274: 9192: 8919: 8213: 8179: 7758: 7589: 7501: 6817: 6173:"Genital Herpes Dating Sites Review | Best Herpes Dating Sites for Genital HSV Singles in 2016" 5065:"Age-specific prevalence of infection with herpes simplex virus types 2 and 1: a global review" 4854:"Age-specific prevalence of infection with herpes simplex virus types 2 and 1: a global review" 1667:
Chayavichitsilp P, Buckwalter JV, Krakowski AC, Friedlander SF (April 2009). "Herpes simplex".
949: 945: 832: 735: 692: 582: 414: 258: 9182: 5196:"Predominance of herpes simplex virus type 1 from patients with genital herpes in Nova Scotia" 4972: 4085: 1921: 1793:
Rowe, AM; St Leger, AJ; Jeon, S; Dhaliwal, DK; Knickelbein, JE; Hendricks, RL (January 2013).
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Koelle DM, Corey L (2008). "Herpes Simplex: Insights on Pathogenesis and Possible Vaccines".
3428: 2834: 2778: 1959:"An estimate of the global prevalence and incidence of herpes simplex virus type 2 infection" 1516: 1367: 1338: 872: 665: 518: 445: 4054: 702:
Herpetic sycosis is a recurrent or initial herpes simplex infection affecting primarily the
10741: 10642: 10380: 10365: 9931: 9864: 9470: 9202: 8742: 8383: 8373: 8087: 7897: 7863: 7753: 7637: 6837: 6635: 6610: 5820: 5720: 5548: 5422: 4640:"Reactivation of latent herpes simplex virus infection by ultraviolet light: a human model" 4427: 2801: 1233:
plays a key role in reactivation of the dormant virus. Changes in the immune system during
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is a recurrent or initial herpes simplex infection affecting primarily the hair follicles.
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against the virus can confirm a previous infection but will be negative in new infections.
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Martinez V, Caumes E, Chosidow O (2008). "Treatment to prevent recurrent genital herpes".
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Kaufman HE, Howard GM (August 1962). "Therapy of experimental herpes simplex keratitis".
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Research has gone into vaccines for both prevention and treatment of herpes infections.
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and headaches. Over time, episodes of active disease decrease in frequency and severity.
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Xu, F; MR Sternberg; SL Gottlieb; SM Berman; LE Markowitz; et al. (23 April 2010).
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is an HSV infection in an infant. It is a rare but serious condition, usually caused by
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Dobson CB, Itzhaki RF (1999). "Herpes simplex virus type 1 and Alzheimer's disease".
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taken by someone who has the infection can also reduce spread. There is no available
318: 187: 179: 126: 6227: 6143: 5940: 5848: 5748: 4803: 4589: 4346: 4167: 4039: 3691: 3666: 3487: 3444: 3363: 2994: 2912:"Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry" 2896: 2736: 2693: 2569: 2479: 2358: 2307: 2214: 2171: 2115: 1871: 1696: 1218:
Many HSV-infected people experience recurrence within the first year of infection.
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antivirals are effective for herpes labialis, including aciclovir, penciclovir, and
272:. It may have minimal symptoms or form blisters that break open and result in small 10507: 10142: 10132: 10096: 10005: 9756: 9695: 9629: 9619: 9567: 9465: 9360: 9197: 8849: 8490: 8479: 8260: 8101: 7564: 7413: 7319: 7267: 7137: 6912: 6847: 6536: 6096: 6088: 6013: 5967: 5920: 5883: 5875: 5828: 5783: 5775: 5728: 5675: 5667: 5626: 5622: 5618: 5579: 5544: 5506: 5498: 5457: 5418: 5354: 5346: 5274: 5258: 5217: 5207: 5154: 5117: 5076: 4903: 4865: 4826: 4783: 4721: 4686: 4651: 4612: 4569: 4504: 4486: 4445: 4435: 4326: 4270: 4266: 4251: 4247: 4220: 4216: 4139: 4019: 3984: 3947: 3939: 3898: 3857: 3811: 3770: 3729: 3612: 3608: 3604: 3563: 3555: 3467: 3424: 3389: 3341: 3300: 3230: 3222: 3183: 3135: 3127: 3088: 3021: 2972: 2931: 2923: 2876: 2716: 2673: 2638: 2599: 2595: 2549: 2514: 2424: 2381: 2330: 2277: 2194: 2151: 2099: 2095: 2027: 2019: 1978: 1970: 1894: 1851: 1814: 1806: 1676: 1632: 1612: 1574: 1322: 1179:. While a number of small studies show possible benefit from monolaurin, L-lysine, 739: 670: 592: 535: 410: 402: 286: 92: 6260: 3263: 3226: 1371:
is especially true of new or potential sexual partners whom they consider casual.
1068:(acetaminophen) can reduce pain and fever. Topical anesthetic treatments such as 568: 10875: 10663: 10449: 10244: 10137: 9973: 9892: 9872: 9796: 9781: 9651: 9555: 9523: 9494: 9416: 9342: 9138: 9021: 9011: 8956: 8941: 8671: 8346: 8267: 7841: 7549: 7476: 7147: 6862: 6707: 6645: 6501: 5832: 5779: 5311: 4787: 4573: 4491: 3533: 3010:"Oral herpes simplex virus type 2 reactivation in HIV-positive and -negative men" 2518: 1327: 723: 715: 489: 5972: 5955: 5462: 5445: 3943: 3862: 3845: 3775: 3758: 3471: 3305: 3288: 10887: 10829: 10781: 10751: 10619: 10550: 10517: 10239: 9978: 9712: 9592: 9387: 9172: 8985: 8629: 8600: 8573: 8550: 8363: 8126: 8039: 7778: 7609: 7599: 7516: 7058: 6886: 4690: 4616: 4241: 4023: 3734: 3717: 3559: 3187: 2961:"A Novel Role for 3-O-Sulfated Heparan Sulfate in Herpes Simplex Virus 1 Entry" 1578: 1208: 1101: 868: 798: 553: 508: 437: 369: 337: 310: 254: 6512: 6459: 6455: 5764:"Target-Organ Treatment of Neurotropic Virus Disease with Interferon Inducers" 4330: 4084:
Agrawal, Caroline A. Hastings, Joseph Torkildson, Anurag Kishor (2012-04-30).
3330:"Once-daily valacyclovir to reduce the risk of transmission of genital herpes" 2198: 2023: 1898: 1855: 1616: 1155:
Evidence is insufficient to support use of many of these compounds, including
525: 10897: 10731: 10609: 10437: 10256: 10020: 10000: 9909: 9776: 9736: 9533: 9294: 9269: 9244: 9222: 9006: 8996: 8961: 8708: 8606: 8429: 8320: 8065: 7851: 7846: 7594: 7569: 7524: 7486: 7354: 7221: 7081: 7033: 6965: 6937: 5270: 5017: 4500: 4151: 3667:"Condom Effectiveness – Male Latex Condoms and Sexually Transmitted Diseases" 3393: 2607: 2393: 2342: 2291: 1666: 1288: 1281: 1196: 997: 941: 936: 884: 703: 588: 545: 425: 405:). More serious disorders occur when the virus infects and damages the eye ( 322: 314: 305:
still occur when symptoms are not present. Genital herpes is classified as a
242: 197: 32: 6451: 6447: 5262: 5122: 5105: 3593:"A pooled analysis of the effect of condoms in preventing HSV-2 acquisition" 3008:
Kim H, Meier A, Huang M, Kuntz S, Selke S, Celum C, Corey L, Wald A (2006).
2880: 2057:"Countering Creeping Confusion: A Proposal to Re-Name Herpes Virus TAXONOMY" 1237:
may play a role in HSV-1 reactivation. Concurrent infections, such as viral
10582: 10358: 10353: 10338: 10318: 10288: 10121: 9830: 9771: 9702: 9624: 9614: 9582: 9545: 9506: 9498: 9113: 9068: 9053: 8951: 8946: 8758: 8590: 8513: 8503: 8450: 8410: 8401: 8249: 7969: 7935: 7871: 7539: 7111: 7091: 6906: 6901: 6891: 6732: 6110: 6025: 6017: 5395: 5288: 5231: 5166: 5131: 5090: 5025: 4946: 4915: 4907: 4892: 4879: 4838: 4795: 4760: 4624: 4546: 4518: 4459: 4440: 4400: 4373: 4338: 4278: 4259: 4228: 4197: 4159: 4031: 3996: 3825: 3816: 3799: 3743: 3626: 3577: 3436: 3401: 3355: 3195: 3149: 3035: 2986: 2945: 2888: 2763: 2728: 2685: 2650: 2642: 2615: 2561: 2526: 2436: 2299: 2206: 2163: 2107: 2041: 1992: 1906: 1863: 1828: 1779: 1688: 1624: 1586: 1257: 1245: 1234: 1204: 1109: 1014: 743: 353: 213: 10718: 8038: 5981: 5897: 5840: 5797: 5689: 5640: 5591: 5520: 5471: 5368: 5212: 4733: 4698: 4663: 4581: 4288:. If this is an intentional citation to a retracted paper, please replace 3961: 3912: 3871: 3784: 3479: 3314: 3244: 3100: 2401: 2350: 1974: 68: 10776: 10766: 10756: 10673: 10668: 10599: 9673: 9634: 9453: 9329: 9289: 9157: 9078: 9058: 8747: 7974: 7880: 7856: 7574: 7399: 7101: 6767: 5740: 5430: 5106:"Incidence of herpes simplex virus type 2 infection in the United States" 4475:"De novo synthesis of VP16 coordinates the exit from HSV latency in vivo" 4473:
Thompson, Richard L.; Preston, Chris M.; Sawtell, Nancy M. (2009-03-01).
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It should not be confused with conditions caused by other viruses in the
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may result in spread of herpes simplex throughout the eczematous areas.
10736: 10522: 10348: 10116: 9946: 9887: 9825: 9815: 9808: 9803: 9741: 9724: 9668: 9639: 9560: 9421: 9399: 9284: 9264: 8777: 8733: 8390: 8309: 8188: 7993: 7950: 7921: 7916: 7803: 7795: 7534: 7375: 7252: 6970: 6942: 6712: 6172: 5556: 4090:(2nd ed.). Chichester, West Sussex: Wiley-Blackwell. p. 360. 1277: 1222:
precedes development of lesions. Prodromal symptoms include tingling (
1172: 1081: 1077: 1069: 903: 892: 856: 849: 326: 280: 204: 148: 4210: 4143: 3974: 2282: 2265: 325:
or detecting herpes DNA in fluid from blisters. Testing the blood for
10604: 10587: 10323: 10101: 9904: 9528: 9411: 9031: 8926: 8904: 8698: 8661: 8545: 8131: 8055: 7988: 7717: 7677: 7579: 7529: 7293: 6880: 6852: 6757: 6592: 6578: 6531: 4676: 3414: 2780:
The Good News about the Bad News: Herpes: Everything You Need to Know
2252: 2230:"Inquests to be held into deaths of new mothers who died from herpes" 1176: 1160: 1156: 1144: 1105: 1073: 1061: 1057: 985: 864: 811: 719: 645: 626: 599: 549: 429: 349: 269: 250: 209: 76: 6201: 5103: 4639: 2585:"Antiviral treatment for Bell's palsy (idiopathic facial paralysis)" 926:
1980s is more than 98% specific at discriminating HSV-1 from HSV-2.
10614: 10565: 10333: 10086: 10067: 10047: 9868: 9746: 9690: 8936: 8368: 8339: 8334: 8329: 8193: 7826: 7770: 7741: 7669: 7604: 7226: 7206: 7142: 7096: 7038: 6975: 6917: 6737: 6686: 6615: 6368:"Hitchhiking Herpes Virus Aligns with Spread of Human Civilization" 6074: 5570:
Juel-Jensen BE (March 1970). "Varicella and cytosine arabinoside".
5081: 5064: 4870: 4853: 3903: 3886: 3843: 3286: 3026: 3009: 2428: 1363: 1317: 1219: 1164: 1010: 922: 860: 806: 630: 606: 433: 418: 389: 4928: 1092: 695:), accompanied by small white itchy lesions on the surface of the 79:
of the lower lip. Note the blisters in a group marked by an arrow.
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Mertz, G.J. (1993). "Epidemiology of genital herpes infections".
2836:
Sexually Transmitted Diseases: A Practical Guide for Primary Care
2480:
Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007).
1564: 1441: 1433: 1212: 1200: 1180: 1140: 853: 560:(soccer), sometimes acquire a condition caused by HSV-1 known as 341: 265: 5953: 4531: 4056:
Antiviral research : strategies in antiviral drug discovery
3457: 479: 10442: 9914: 9502: 9097: 8358: 7015: 6727: 6722: 6696: 6605: 6442: 6427: 6400: 5002: 3718:"Herpes simplex virus: The importance of asymptomatic shedding" 3287:
Kulhanjian J A, Soroush V, Au DS, et al. (April 2, 1992).
1128: 696: 629:). It is often associated with impaired immune function (e.g. 514: 333: 264:
Oral herpes involves the face or mouth. It may result in small
5910: 5533: 5408: 5247:"Evolutionary Origins of Human Herpes Simplex Viruses 1 and 2" 4638:
Perna JJ, Mannix ML, Rooney JF, Notkins AL, Straus SE (1987).
2832: 107: 8043: 7818: 6681: 5332: 3798:
Brown ZA, Wald A, Morrow RA, Selke S, Zeh J, Corey L (2003).
3542:
Andrei G; Lisco A; Vanpouille C; et al. (October 2011).
2264:
van Riel, Debby; Verdijk, Rob; Kuiken, Thijs (January 2015).
2142:
Gupta R, Warren T, Wald A (December 2007). "Genital herpes".
1120:. Aciclovir was the first discovered and is now available in 687:, a primary infection, typically presents as swelling of the 373: 273: 144: 10882: 6000:
Kimberlin DW, Lin CY, Jacobs RF, et al. (August 2001).
3756: 521:
on the outer surface of the genitals resembling cold sores.
498: 101: 8499: 8351: 7262: 6781: 6600: 5954:
Whitley R, Arvin A, Prober C, et al. (February 1991).
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Online Journal of Community and Person-Centered Dermatology
1956: 1168: 595: 6077:"Determinants of disclosure of genital herpes to partners" 5862:
Babiuk LA, Meldrum B, Gupta VS, Rouse BT (December 1975).
4359: 3759:"The acquisition of herpes simplex virus during pregnancy" 1602: 1366:, fear of being found out, and self-destructive feelings. 677:
is an infection with herpesvirus in patients with chronic
301:
involves any part of the body of a newborn, among others.
8893: 7831: 7659: 4978:. Center for Disease Control and Prevention. 2010-03-09. 3844:
Brown ZA, Benedetti J, Ashley R, et al. (May 1991).
3327: 2958: 1741:(9 ed.). Elsevier Health Sciences. pp. 836–37. 1375: 6292: 5810: 4637: 4387:
Beauman, JG (Oct 15, 2005). "Genital herpes: a review".
3925: 3202: 2809:"AHMF: Preventing Sexual Transmission of Genital herpes" 1792: 1316:
Herpes has been known for at least 2,000 years. Emperor
424:
In all cases, HSV is never removed from the body by the
5861: 4886: 4746: 3884: 3113: 2839:. Springer Science & Business Media. pp. 50–. 2454: 2371: 1884: 1766:
Wu, IB; Schwartz, RA (March 2007). "Herpetic whitlow".
1195:
Following active infection, herpes viruses establish a
871:) also resemble intraoral herpes, but do not present a 6041:"Genital Herpes: Psychosexual Impacts and Counselling" 5607:"Inhibitory Effect of Heparin on Herpes Simplex Virus" 5333:
Chow AW, Roland A, Fiala M, et al. (March 1973).
4773: 4472: 3328:
Corey L, Wald A, Patel R, et al. (January 2004).
10859: 5702: 5062: 4711: 3379: 2263: 831:
HSV-1 causes primarily mouth, throat, face, eye, and
448:
herpes. However, infection with herpes can be fatal.
110: 8879: 6405: 3797: 2079: 1957:
Looker, KJ; Garnett, GP; Schmid, GP (October 2008).
104: 5193: 4413: 2539: 2457:
Andrews' Diseases of the Skin: clinical Dermatology
98: 95: 10293:Jaw joints, chewing muscles and bite abnormalities 5144: 4052: 3926:O'Mahony C, Timms MS, Ramsden RT (December 1988). 3173: 3114:Reuven NB, Staire AE, Myers RS, Weller SK (2003). 3047: 3045: 3007: 1887:Obstetrics and Gynecology Clinics of North America 9156: 6579:Diseases of the skin and appendages by morphology 4183: 3282: 3280: 591:or from a peripheral site on the face, along the 356:can lessen the severity of symptomatic episodes. 10895: 9493: 5995: 5993: 5991: 4714:Oral Surg Oral Med Oral Pathol Oral Radiol Endod 3257: 1841: 10648:Teeth, jaws, tongue and associated soft tissues 4973:"CDC Study Finds U.S. Herpes Rates Remain High" 3169: 3167: 3165: 3163: 3161: 3159: 3042: 2910:Akhtar, Jihan; Shukla, Deepak (December 2009). 2862: 2860: 2858: 2856: 2833:Anita L. Nelson; Jo Ann Woodward (2007-12-14). 2663: 2141: 2137: 2135: 2133: 2131: 2129: 2127: 2125: 810:infection. Herpes simplex is a double-stranded 738:. In the presence of a certain gene variation ( 734:HSV-1 has been proposed as a possible cause of 9260:Hereditary benign intraepithelial dyskeratosis 5604: 5569: 5328: 5326: 3839: 3837: 3835: 3757:Brown ZA, Selke S, Zeh J, et al. (1997). 3715: 3277: 2628: 2455:James, William D.; Berger, Timothy G. (2006). 397:HSV infection causes several distinct medical 27:Viral disease caused by herpes simplex viruses 10218:Neuralgia-inducing cavitational osteonecrosis 8865: 8814:Asymmetric periflexural exanthem of childhood 8024: 7645: 7064:Pityriasis lichenoides et varioliformis acuta 6564: 6123: 5988: 5484: 5443: 5381: 4851: 4602: 3694:. Center for Disease Control and Prevention. 3669:. Center for Disease Control and Prevention. 3504:. Center for Disease Control and Prevention. 2706: 2504: 2184: 1952: 1950: 1919: 1332:A System of Rational and Practical Chirurgery 1104:are effective for treating herpes, including 944:(also known as shingles), which is caused by 838:HSV-2 causes primarily anogenital infections. 10919:Sexually transmitted diseases and infections 6718:Dermatofibroma (benign fibrous histiocytoma) 6038: 5947: 5855: 5804: 5761: 5755: 5653: 5647: 5598: 5563: 5478: 5437: 5375: 5179:: CS1 maint: DOI inactive as of July 2024 ( 5097: 4845: 4810: 4767: 4740: 4596: 4525: 4407: 4353: 4235: 4204: 4128: 4114:: CS1 maint: multiple names: authors list ( 3968: 3885:Whitley RJ, Kimberlin DW, Roizman B (1998). 3156: 3074: 3072: 2909: 2853: 2533: 2178: 2122: 6144:"Herpes groups on Meetup | HerpesDateSites" 5696: 5323: 4816: 4705: 4670: 4631: 4553: 4316: 4244:The Cochrane Database of Systematic Reviews 4213:The Cochrane Database of Systematic Reviews 3919: 3832: 3078: 2592:The Cochrane Database of Systematic Reviews 2008:"The Origin and the Use of the Word Herpes" 1511: 1509: 1507: 1505: 1503: 1501: 1499: 1497: 1495: 1493: 1491: 1489: 1487: 1485: 1483: 1481: 1407:In the UK, the Herpes Association (now the 8872: 8858: 8617:Papular purpuric gloves and socks syndrome 8031: 8017: 7652: 7638: 6571: 6557: 5904: 5713:Annals of the New York Academy of Sciences 5402: 5300: 5298: 4302:|...|intentional=yes}} 4122: 4009: 3878: 2783:. New Harbinger Publications. p. 28. 2700: 2505:Tankéré F, Bernat I (September 2009). "". 2450: 2448: 2446: 1947: 1844:Current Neurology and Neuroscience Reports 1765: 1479: 1477: 1475: 1473: 1471: 1469: 1467: 1465: 1463: 1461: 417:, although this is often dependent on the 67: 6100: 5971: 5887: 5787: 5679: 5630: 5527: 5510: 5461: 5358: 5278: 5221: 5211: 5121: 5080: 4869: 4508: 4490: 4449: 4439: 4179: 4177: 3951: 3902: 3861: 3815: 3774: 3733: 3616: 3567: 3345: 3321: 3304: 3234: 3139: 3069: 3025: 2976: 2935: 2281: 2031: 1982: 1963:Bulletin of the World Health Organization 1818: 1662: 1560: 1558: 1556: 1554: 1552: 1550: 1548: 1546: 1544: 1542: 929: 621:Symptoms may include painful swallowing ( 432:of the neuron, and becomes latent in the 289:typically involves the fingers or thumb, 10914:Herpes simplex virus–associated diseases 5304: 4414:Stumpf MP, Laidlaw Z, Jansen VA (2002). 4132:Journal of Oral Pathology & Medicine 4059:. Washington, DC: ASM Press. p. 1. 3429:10.7326/0003-4819-143-10-200511150-00007 3408: 3260:"Percentage of people with herpes drops" 2749: 2473: 1660: 1658: 1656: 1654: 1652: 1650: 1648: 1646: 1644: 1642: 1598: 1596: 1091: 388: 143:Blisters that break open and form small 10845:Oral manifestations of systemic disease 9994:Acute necrotizing ulcerative gingivitis 8288:Kaposi's sarcoma-associated herpesvirus 6342:"Can herpes kill you? - Technology Org" 6032: 5654:Allen LB, Sidwell RW (September 1972). 5485:Fiala M, Chow A, Guze LB (April 1972). 5444:McKelvey EM, Kwaan HC (November 1969). 5295: 4386: 4083: 3375: 3373: 2866: 2443: 2005: 1458: 1150: 14: 10896: 10031:As a manifestation of systemic disease 7371:Disseminated intravascular coagulation 6068: 5762:Allen LB, Cochran KW (November 1972). 4776:Current Opinion in Infectious Diseases 4174: 3584: 3208: 2776: 1920:Hoyle, Alice; McGeeney, Ester (2019). 1703: 1539: 1353: 729: 10818: 10717: 10641: 10399: 10278: 10064: 9854: 9492: 9155: 9095: 8983: 8891: 8853: 8012: 7633: 6552: 6365: 4935:Morbidity and Mortality Weekly Report 4003: 3716:Koelle, D.M.; Wald, A. (April 2000). 2320: 2227: 1923:Great Relationships and Sex Education 1734: 1639: 1593: 1527:from the original on 31 December 2014 898: 746:, which may lead to its development. 384: 344:and once infected, there is no cure. 313:to the nerve cell bodies, where they 31:For all types of herpes viruses, see 9877:Gums and tooth-supporting structures 8819:Post-vaccination follicular eruption 6374:from the original on 22 October 2013 6257:"American Social Health Association" 6234:from the original on 21 October 2014 5549:10.1093/infdis/133.supplement_2.a178 5423:10.1093/infdis/133.supplement_2.a184 5159:10.1080/j.1600-0412.2000.079008693.x 4831:10.1146/annurev.med.59.061606.095540 3370: 3258:Carla K. Johnson (August 23, 2006). 2323:Journal of the Neurological Sciences 1799:Progress in Retinal and Eye Research 984:In October 2011, the anti-HIV drug 964:may also have a similar appearance. 956:due to similar lesions on the skin. 317:. Causes of recurrence may include: 10528:Papillary cystadenoma lymphomatosum 10400: 10371:Temporomandibular joint dysfunction 1378:took the top spot for STD stigma). 1199:infection in sensory and autonomic 1084:can also relieve itching and pain. 24: 10929:Virus-related cutaneous conditions 10909:Conditions of the mucous membranes 9645:Maxillary lateral incisor agenesis 9129:Inflammatory papillary hyperplasia 8488: 7196: 7153:Postinflammatory hyperpigmentation 5733:10.1111/j.1749-6632.1977.tb21957.x 5605:Nahmias AJ, Kibrick S (May 1964). 3262:. Associated Press. Archived from 2063:. Dr. David Elpern. Archived from 1096:The antiviral medication aciclovir 991: 749: 644: 605: 567: 524: 497: 478: 451: 220:(acetaminophen), topical lidocaine 25: 10940: 7956:Pelvic inflammatory disease (PID) 7054:Transient acantholytic dermatosis 6390: 4953:from the original on 25 June 2011 4416:"Herpes viruses hedge their bets" 3502:"Genital Herpes – CDC Fact Sheet" 2228:Marsh, Sarah (30 December 2021). 2054: 1517:"Genital Herpes – CDC Fact Sheet" 1381: 1362:, fear of rejection, feelings of 1347:U.S. Food and Drug Administration 1239:upper respiratory tract infection 822: 10881: 10869: 10747:Cutaneous sinus of dental origin 10684:Obesity hypoventilation syndrome 10679:Central hypoventilation syndrome 10561:Carcinoma ex pleomorphic adenoma 9989:Necrotizing periodontal diseases 9969:Hereditary gingival fibromatosis 8881:Oral and maxillofacial pathology 8834:Viral-associated trichodysplasia 8219:Modified varicella-like syndrome 8042:, symptoms and signs related to 7163:Idiopathic guttate hypomelanosis 6359: 6334: 6310: 6285: 6267: 6249: 6220: 6194: 6165: 6136: 6124:Miranda Hitti (24 August 2007). 6117: 5110:American Journal of Epidemiology 4104:from the original on 2016-04-30. 4073:from the original on 2016-05-02. 3132:10.1128/jvi.77.13.7425-7433.2003 3053:"Herpes simplex pathophysiology" 2928:10.1111/j.1742-4658.2009.07402.x 2797:from the original on 2016-05-27. 2678:10.2165/11310910-000000000-00000 2554:10.1097/00129492-200501000-00020 2386:10.1001/jama.1982.03320280037026 1811:10.1016/j.preteyeres.2012.08.002 1755:from the original on 2017-09-06. 1386: 91: 10593:Chronic sclerosing sialadenitis 10230:Osteoporotic bone marrow defect 9684:Keratocystic odontogenic tumour 8541:Epidermodysplasia verruciformis 7998:Non-gonococcal urethritis (NGU) 7661:Sexually transmitted infections 7173:Hypopigmented mycosis fungoides 6366:Foley, James A. (21 Oct 2013). 6299:from the original on 2015-07-26 6208:from the original on 4 May 2016 6183:from the original on 2017-05-22 6154:from the original on 2017-04-06 6081:Sexually Transmitted Infections 5251:Molecular Biology and Evolution 5238: 5187: 5138: 5056: 5032: 4996: 4985:from the original on 2016-03-06 4965: 4922: 4466: 4380: 4310: 4077: 4046: 3791: 3750: 3709: 3698:from the original on 2011-10-01 3684: 3673:from the original on 2011-10-02 3659: 3641:"Putting Herpes in Perspective" 3633: 3519: 3508:from the original on 2014-01-30 3494: 3451: 3251: 3209:Ashley RL, et al. (1988). 3107: 3001: 2952: 2903: 2826: 2770: 2743: 2657: 2622: 2576: 2498: 2408: 2365: 2314: 2257: 2240: 2221: 2048: 1999: 1913: 1878: 1567:Dental Clinics of North America 1393:National Herpes Resource Center 1264: 910:(DFA) studies to detect virus, 709: 10578:Sclerosing polycystic adenosis 10413:Benign lymphoepithelial lesion 8556:Verrucae palmares et plantares 7414:Lichen sclerosis et atrophicus 7122:Subcorneal pustular dermatosis 6748:Infantile digital fibromatosis 6295:. Herpes Viruses Association. 6050:(June): 125–34. Archived from 5623:10.1128/JB.87.5.1060-1066.1964 5063:Smith JS, Robinson NJ (2002). 4852:Smith JS, Robinson NJ (2002). 4271:10.1002/14651858.CD006700.pub3 4252:10.1002/14651858.CD006700.pub2 4221:10.1002/14651858.CD006706.pub2 3609:10.1001/archinternmed.2009.177 2600:10.1002/14651858.CD001869.pub8 2100:10.1016/j.biopsych.2003.10.008 1835: 1786: 1759: 1728: 1271:Epidemiology of herpes simplex 842: 726:in those with severe disease. 336:use decreases the risk. Daily 307:sexually transmitted infection 13: 1: 10772:Melkersson–Rosenthal syndrome 10721:Soft tissues around the mouth 10418:Ectopic salivary gland tissue 8773:Hand, foot, and mouth disease 8268:Cytomegalic inclusion disease 7006:Epidermolysis bullosa simplex 6843:Langerhans cell histiocytosis 6322:www.precisionvaccinations.com 5925:10.1016/S0140-6736(79)92428-0 5584:10.1016/S0140-6736(70)90815-9 4726:10.1016/S1079-2104(97)90342-5 4656:10.1016/S0190-9622(87)70232-1 3989:10.1016/S0190-9622(99)70260-4 3597:Archives of Internal Medicine 3227:10.1128/JCM.26.4.662-667.1988 3093:10.1016/S0891-5520(20)30561-4 2978:10.1016/S0092-8674(00)80058-6 2721:10.1016/S0197-4580(99)00055-X 2156:10.1016/S0140-6736(07)61908-4 1451: 1428:As of October 2022, the U.S. 1213:latency-associated transcript 1185:randomized controlled studies 1051: 1024: 967: 685:Herpetic keratoconjunctivitis 625:) and difficulty swallowing ( 9942:Gingival cyst of the newborn 9551:Failure of eruption of teeth 9255:Hand, foot and mouth disease 9240:Focal epithelial hyperplasia 9178:Angina bullosa haemorrhagica 9124:Palatal cysts of the newborn 9047:Transient lingual papillitis 8785:Foot-and-mouth disease virus 7730:Mycoplasma hominis infection 7482:Systemic lupus erythematosus 7237:Systemic lupus erythematosus 6928:Systemic lupus erythematosus 6275:"The Herpes Resource Center" 6177:genitalherpesdatingsites.org 5868:Antimicrob. Agents Chemother 5833:10.1126/science.177.4050.705 5780:10.1128/IAI.6.5.819-823.1972 5660:Antimicrob. Agents Chemother 5491:Antimicrob. Agents Chemother 5339:Antimicrob. Agents Chemother 5194:Forward KR, Lee SHS (2003). 4788:10.1097/QCO.0b013e3282f3d9d3 4574:10.1177/00220345740530040501 4492:10.1371/journal.ppat.1000352 4420:Proc. Natl. Acad. Sci. U.S.A 3692:"STD Facts – Genital Herpes" 3643:. UBM Medica. Archived from 2519:10.1016/j.revmed.2008.12.006 2335:10.1016/0022-510X(82)90183-6 1190: 1087: 1033: 954:hand, foot and mouth disease 817: 714:Although the exact cause of 363: 7: 10904:Biology of bipolar disorder 10470:Salivary gland diverticulum 10433:Necrotizing sialometaplasia 9444:Smokeless tobacco keratosis 9356:Basaloid squamous carcinoma 8829:Eruptive pseudoangiomatosis 8720:Congenital rubella syndrome 8465:Molluscum contagiosum virus 6763:Lymphangioma circumscriptum 6048:The Canadian Journal of CME 6039:Vezina C, Steben M (2001). 5973:10.1056/NEJM199102143240703 5463:10.1182/blood.V34.5.706.706 5384:Investigative Ophthalmology 4053:Robert L. LaFemina (2009). 3944:10.1136/bmj.297.6661.1468-a 3863:10.1056/NEJM199105023241804 3776:10.1056/NEJM199708213370801 3472:10.7326/0003-4819-116-3-197 3460:Annals of Internal Medicine 3417:Annals of Internal Medicine 3306:10.1056/NEJM199204023261403 1414: 1391:A source of support is the 958:Lymphangioma circumscriptum 908:direct fluorescent antibody 10: 10945: 10480:Salivary gland hyperplasia 10428:HIV salivary gland disease 9937:Gingival cyst of the adult 9383:Oral florid papillomatosis 9096: 8984: 8209:Disseminated herpes zoster 8147:Herpetic gingivostomatitis 7585:Mucous membrane pemphigoid 6318:"mRNA-1608 Herpes Vaccine" 4617:10.1016/j.joms.2006.07.019 4024:10.1517/14656566.4.10.1809 3560:10.1016/j.chom.2011.08.015 3188:10.1016/j.jaad.2007.06.027 1738:Mosby's Medical Dictionary 1579:10.1016/j.cden.2013.12.001 1418: 1409:Herpes Viruses Association 1343:disseminated herpes zoster 1308: 1268: 1134: 471:Herpetic gingivostomatitis 374: 29: 10825: 10819: 10814: 10727: 10719:Orofacial soft tissues – 10713: 10654: 10637: 10485:Salivary gland hypoplasia 10408: 10395: 10299: 10274: 10213:Bisphosphonate-associated 10107:Idiopathic osteosclerosis 10082: 10060: 9883: 9850: 9578:Dentinogenesis imperfecta 9514: 9488: 9168: 9151: 9104: 9091: 9042:Median rhomboid glossitis 8992: 8979: 8900: 8887: 8806: 8756: 8731: 8696: 8669: 8660: 8627: 8588: 8564: 8477: 8443: 8420:Bovine papular stomatitis 8399: 8318: 8307: 8276: 8231: 8177: 8155: 8085: 8074: 8063: 8054: 8050: 7932: 7817: 7794: 7769: 7668: 7548: 7515: 7459: 7444: 7435: 7392: 7363: 7342: 7333: 7286: 7245: 7214: 7203: 7185: 7130: 7072: 7014: 6951: 6871: 6800: 6789: 6780: 6695: 6659: 6591: 6584: 6522: 6409: 6293:"Helping You With Herpes" 5147:Acta Obstet Gynecol Scand 4389:American Family Physician 4331:10.1517/14656561003691847 3928:"Local anesthetic creams" 3182:(5): 737–63, quiz 764–6. 2482:Dermatology: 2-Volume Set 2199:10.1007/s11908-000-0084-y 2024:10.1017/S002572730002737X 1899:10.1016/j.ogc.2014.08.006 1856:10.1007/s11910-013-0414-8 1715:World Health Organization 1617:10.1007/s00520-010-0900-3 916:polymerase chain reaction 319:decreased immune function 224: 203: 186: 180:Decreased immune function 173: 162: 154: 137: 125: 83: 75: 66: 58: 53: 10792:Orofacial granulomatosis 10571:Mucoepidermoid carcinoma 10556:Adenoid cystic carcinoma 10490:Salivary gland neoplasms 10281:Temporomandibular joints 10252:Periapical periodontitis 9984:Linear gingival erythema 9752:Regional odontodysplasia 9598:Enamel hypocalcification 8892: 8839:Gianotti–Crosti syndrome 8640:Merkel cell polyomavirus 8526:Laryngeal papillomatosis 8112:Herpes simplex keratitis 7694:lymphogranuloma venereum 7350:Thrombocytopenic purpura 6996:Dermatitis herpetiformis 6981:Acute contact dermatitis 6933:Pityriasis rubra pilaris 6858:Wiskott–Aldrich syndrome 6828:Lichen simplex chronicus 6708:Epidermal inclusion cyst 5307:"The New Scarlet Letter" 4691:10.1093/infdis/166.3.500 4605:J. Oral Maxillofac. Surg 4319:Expert Opin Pharmacother 4012:Expert Opin Pharmacother 3887:"Herpes simplex viruses" 3735:10.1093/jac/45.suppl_4.1 3722:J. Antimicrob. Chemother 3394:10.1001/jama.285.24.3100 3081:Infect Dis Clin North Am 2270:The Journal of Pathology 1446:out-of-Africa hypothesis 1248:; and exposure to wind, 962:dermatitis herpetiformis 656: 579:Herpesviral encephalitis 421:of the infected person. 297:involves the brain, and 295:herpesviral encephalitis 291:herpes simplex keratitis 237:, often known simply as 169:spread by direct contact 10689:Obstructive sleep apnea 10455:Salivary duct stricture 10235:Paget's disease of bone 9732:Pulp canal obliteration 9573:Dentin hypersensitivity 9519:Amelogenesis imperfecta 9371:Squamous cell carcinoma 9351:Adenosquamous carcinoma 9338:Squamous cell papilloma 9315:Melanocytic oral lesion 8790:Boston exanthem disease 8460:Yaba monkey tumor virus 8142:Herpetiform esophagitis 8122:Neonatal herpes simplex 7711:Klebsiella granulomatis 7615:Squamous-cell carcinoma 7610:Systemic histoplasmosis 7001:Porphyria cutanea tarda 6631:Squamous-cell carcinoma 6370:. NatureWorldNews.com. 6148:www.herpesdatesites.com 6128:. WebMD. Archived from 5305:John Leo (1982-08-02). 5161:(inactive 2024-07-14). 3548:Cell Host & Microbe 2881:10.1185/030079905X61901 1675:(4): 119–29, quiz 130. 1421:Herpes simplex research 867:. Common mouth ulcers ( 662:Neonatal herpes simplex 40:Herpes (disambiguation) 10835:Hemifacial hypertrophy 10802:Pyostomatitis vegetans 10475:Salivary gland fistula 10465:Salivary gland atresia 10460:Salivary gland aplasia 10314:Mandibular dislocation 10285:muscles of mastication 10163:Calcifying odontogenic 9792:Vertical root fracture 9787:Cracked tooth syndrome 9762:Shovel-shaped incisors 9657:Wisdom tooth impaction 9539:Early childhood caries 9405:Benign mucous membrane 9366:Spindle cell carcinoma 9275:Intraoral dental sinus 9193:Burning mouth syndrome 8214:Zoster-associated pain 7759:Ureaplasma urealyticum 7590:Cicatricial pemphigoid 7507:Acne keloidalis nuchae 7502:Folliculitis decalvans 6202:"Herpes Support Forum" 6018:10.1542/peds.108.2.230 5768:Infection and Immunity 4908:10.1001/jama.296.8.964 4441:10.1073/pnas.232546899 3817:10.1001/jama.289.2.203 2777:Warren, Terri (2009). 2643:10.3233/JAD-2008-13405 1926:. Taylor and Francis. 1711:"Herpes simplex virus" 1097: 950:differential diagnosis 946:varicella zoster virus 930:Differential diagnosis 833:central nervous system 693:blepharoconjunctivitis 649: 610: 583:herpesviral meningitis 572: 529: 502: 483: 394: 10644:Stomatognathic system 10546:Acinic cell carcinoma 10168:Glandular odontogenic 9320:Molluscum contagiosum 8646:Merkel cell carcinoma 8569:Bovine papillomavirus 7905:Molluscum contagiosum 7784:Trichomonas vaginalis 7723:Neisseria gonorrhoeae 7699:Chlamydia trachomatis 7492:Loose anagen syndrome 7419:Necrobiosis lipoidica 7355:Actinic/solar purpura 7029:Insect bite reactions 6818:Seborrheic dermatitis 6641:Merkel-cell carcinoma 6621:Molluscum contagiosum 6126:"Stigma Still Strong" 5263:10.1093/molbev/msu185 5123:10.1093/aje/153.9.912 4644:J. Am. Acad. Dermatol 4294:|...}} 4265:(Retracted, see 3977:J. Am. Acad. Dermatol 3176:J. Am. Acad. Dermatol 2459:. Saunders Elsevier. 2006:Beswick, TSL (1962). 1975:10.2471/blt.07.046128 1402: 1368:Herpes support groups 1339:deoxyribonucleic acid 1095: 666:vertical transmission 648: 609: 571: 528: 501: 482: 392: 10787:Oral Crohn's disease 10742:Basal cell carcinoma 10381:Condylar hyperplasia 10366:Maxillary hypoplasia 9932:Gingival enlargement 9865:periodontal ligament 9471:Verruciform xanthoma 9203:Condyloma acuminatum 8743:Alphavirus infection 8607:Erythema infectiosum 8384:Progressive vaccinia 8374:Generalized vaccinia 8199:Herpes zoster oticus 7865:Human papillomavirus 7754:Ureaplasma infection 7315:Annulare centrifugum 6838:Glucagonoma syndrome 6636:Basal-cell carcinoma 6611:Seborrheic keratosis 6132:on 16 November 2013. 3540:. Research article: 3347:10.1056/NEJMoa035144 2484:. St. Louis: Mosby. 2067:on 23 September 2018 1681:10.1542/pir.30-4-119 1523:. December 8, 2014. 1151:Alternative medicine 338:antiviral medication 247:herpes simplex virus 167:Herpes simplex virus 38:For other uses, see 10797:Perioral dermatitis 10533:Pleomorphic adenoma 10513:Monomorphic adenoma 10503:Canalicular adenoma 10376:Condylar hypoplasia 10309:Condylar resorption 10153:Lateral periodontal 10112:Mandibular fracture 10011:Periodontal abscess 9608:Turner's hypoplasia 9376:Verrucous carcinoma 9325:Morsicatio buccarum 9305:Lupus erythematosus 9218:Erythema multiforme 9134:Stomatitis nicotina 8244:Human herpesvirus 6 7683:Haemophilus ducreyi 7560:Aphthous stomatitis 7497:Lichen planopilaris 7472:Androgenic alopecia 7278:Fixed drug eruption 6853:Pemphigus foliaceus 6753:Granular cell tumor 6093:10.1136/sti.79.1.42 5880:10.1128/aac.8.6.643 5825:1972Sci...177..705S 5725:1977NYASA.284..247A 5672:10.1128/aac.2.3.229 5503:10.1128/aac.1.4.354 5351:10.1128/aac.3.3.412 5213:10.1155/2003/168673 4432:2002PNAS...9915234S 3647:on 25 February 2021 2815:on January 21, 2008 2248:Herpes Encephalitis 2187:Curr Infect Dis Rep 1605:Support Care Cancer 1354:Society and culture 756: 736:Alzheimer's disease 730:Alzheimer's disease 415:Alzheimer's disease 192:Based on symptoms, 10840:Facial hemiatrophy 10694:Periodic breathing 10625:Sjögren's syndrome 10498:Basal cell adenoma 10262:Torus mandibularis 10240:Periapical abscess 10223:Osteoradionecrosis 10148:Buccal bifurcation 10127:Intraosseous cysts 10016:Periodontal trauma 9920:Pyogenic granuloma 9767:Supernumerary root 9720:Pulp calcification 9708:Premature eruption 9679:Odontogenic tumors 9476:White sponge nevus 9449:Submucous fibrosis 9393:Smoker's melanosis 9280:Irritation fibroma 9119:High-arched palate 9027:Foliate papillitis 9017:Cunnilingus tongue 9002:Black hairy tongue 8932:Congenital lip pit 8722:("German measles") 8536:Bowenoid papulosis 8107:Herpes gladiatorum 7747:Treponema pallidum 7735:Mycoplasma hominis 7580:Pemphigus vulgaris 7409:Granuloma annulare 7273:Carcinoid syndrome 7158:Tuberous sclerosis 7117:Coccidioidomycosis 6991:Bullous pemphigoid 6986:Pemphigus vulgaris 6918:Secondary syphilis 6808:Contact dermatitis 6523:External resources 6346:www.technology.org 5543:(Suppl): A178–83. 5417:(Suppl): A184–91. 5075:(suppl 1): S3–28. 4864:(Suppl 1): S3–28. 4755:(5 Suppl): 14–18. 4535:Eur. Cytokine Netw 3532:2017-04-09 at the 3215:J. Clin. Microbiol 1795:"Herpes keratitis" 1175:bee products, and 1098: 899:Laboratory testing 754: 718:—a type of facial 650: 617:Herpes esophagitis 611: 573: 562:herpes gladiatorum 540:herpes gladiatorum 530: 503: 484: 395: 385:Signs and symptoms 293:involves the eye, 182:, stress, sunlight 132:Infectious disease 10857: 10856: 10853: 10852: 10810: 10809: 10709: 10708: 10633: 10632: 10538:Sebaceous adenoma 10391: 10390: 10270: 10269: 10181:Median mandibular 10176:Nasopalatine duct 10092:Alveolar osteitis 10056: 10055: 10043:Perio-endo lesion 9925:Congenital epulis 9846: 9845: 9603:Enamel hypoplasia 9484: 9483: 9459:Riga–Fede disease 9310:Melanocytic nevus 9250:Hairy leukoplakia 9213:Epulis fissuratum 9147: 9146: 9087: 9086: 9037:Geographic tongue 8975: 8974: 8847: 8846: 8802: 8801: 8798: 8797: 8768:Coxsackie A virus 8748:Chikungunya fever 8656: 8655: 8612:Reticulocytopenia 8584: 8583: 8473: 8472: 8379:Eczema vaccinatum 8303: 8302: 8256:Exanthema subitum 8227: 8226: 8204:Ophthalmic zoster 8169:B virus infection 8137:Eczema herpeticum 8006: 8005: 7898:HSV-1 & HSV-2 7886:Hepatitis B virus 7627: 7626: 7623: 7622: 7467:Telogen effluvium 7431: 7430: 7427: 7426: 7388: 7387: 7384: 7383: 7329: 7328: 7181: 7180: 7049:Lichen spinulosus 7044:Keratosis pilaris 6923:Mycosis fungoides 6823:Stasis dermatitis 6813:Atopic dermatitis 6776: 6775: 6651:Trichoepithelioma 6626:Actinic keratosis 6546: 6545: 4144:10.1111/jop.12534 4097:978-0-470-67088-0 4066:978-1-55581-439-7 3728:(Suppl T3): 1–8. 2869:Curr Med Res Opin 2846:978-1-59745-040-9 2790:978-1-57224-618-8 2631:J. Alzheimers Dis 2491:978-1-4160-2999-1 2466:978-0-7216-2921-6 2283:10.1002/path.4461 2150:(9605): 2127–37. 1969:(10): 805–12, A. 1933:978-1-35118-825-8 1250:ultraviolet light 1041:caesarean section 889:atopic dermatitis 797:HSV asymptomatic 791: 790: 679:atopic dermatitis 675:Eczema herpeticum 654: 653: 639:organ transplants 635:immunosuppression 368:The name is from 232: 231: 188:Diagnostic method 147:, fever, swollen 48:Medical condition 16:(Redirected from 10936: 10886: 10885: 10874: 10873: 10872: 10865: 10816: 10815: 10715: 10714: 10639: 10638: 10508:Ductal papilloma 10397: 10396: 10276: 10275: 10173:Non-odontogenic: 10158:Globulomaxillary 10097:Buccal exostosis 10062: 10061: 10006:Peri-implantitis 9852: 9851: 9568:Dentin dysplasia 9490: 9489: 9466:Verruca vulgaris 9361:Mucosal melanoma 9208:Darier's disease 9183:Behçet's disease 9153: 9152: 9109:Bednar's aphthae 9093: 9092: 8981: 8980: 8967:Trumpeter's wart 8889: 8888: 8874: 8867: 8860: 8851: 8850: 8667: 8666: 8493: 8486: 8485: 8480:Papillomaviridae 8316: 8315: 8293:Kaposi's sarcoma 8261:Roseola vaccinia 8182: 8162: 8117:Herpetic sycosis 8102:Herpetic whitlow 8090: 8083: 8082: 8072: 8071: 8061: 8060: 8052: 8051: 8033: 8026: 8019: 8010: 8009: 7985: 7966: 7947: 7654: 7647: 7640: 7631: 7630: 7565:Oral candidiasis 7442: 7441: 7340: 7339: 7268:Erythema nodosum 7212: 7211: 7201: 7200: 7194: 7193: 7138:Tinea versicolor 6976:Bullous impetigo 6913:Pityriasis rosea 6848:Lichen sclerosus 6833:Darier's disease 6798: 6797: 6787: 6786: 6743:Kaposi's sarcoma 6589: 6588: 6573: 6566: 6559: 6550: 6549: 6407: 6406: 6384: 6383: 6381: 6379: 6363: 6357: 6356: 6354: 6353: 6338: 6332: 6331: 6329: 6328: 6314: 6308: 6307: 6305: 6304: 6289: 6283: 6282: 6277:. Archived from 6271: 6265: 6264: 6259:. Archived from 6253: 6247: 6246: 6241: 6239: 6224: 6218: 6217: 6215: 6213: 6198: 6192: 6191: 6189: 6188: 6169: 6163: 6162: 6160: 6159: 6140: 6134: 6133: 6121: 6115: 6114: 6104: 6072: 6066: 6065: 6063: 6062: 6056: 6045: 6036: 6030: 6029: 5997: 5986: 5985: 5975: 5951: 5945: 5944: 5908: 5902: 5901: 5891: 5859: 5853: 5852: 5819:(4050): 705–06. 5808: 5802: 5801: 5791: 5759: 5753: 5752: 5700: 5694: 5693: 5683: 5651: 5645: 5644: 5634: 5602: 5596: 5595: 5567: 5561: 5560: 5531: 5525: 5524: 5514: 5482: 5476: 5475: 5465: 5441: 5435: 5434: 5406: 5400: 5399: 5379: 5373: 5372: 5362: 5330: 5321: 5320: 5315:. Archived from 5302: 5293: 5292: 5282: 5257:(9): 2356–2364. 5242: 5236: 5235: 5225: 5215: 5200:Can J Infect Dis 5191: 5185: 5184: 5178: 5170: 5142: 5136: 5135: 5125: 5101: 5095: 5094: 5084: 5060: 5054: 5053: 5051: 5050: 5036: 5030: 5029: 5000: 4994: 4993: 4991: 4990: 4984: 4977: 4969: 4963: 4962: 4960: 4958: 4926: 4920: 4919: 4890: 4884: 4883: 4873: 4849: 4843: 4842: 4814: 4808: 4807: 4771: 4765: 4764: 4744: 4738: 4737: 4709: 4703: 4702: 4674: 4668: 4667: 4635: 4629: 4628: 4600: 4594: 4593: 4557: 4551: 4550: 4529: 4523: 4522: 4512: 4494: 4470: 4464: 4463: 4453: 4443: 4426:(23): 15234–37. 4411: 4405: 4404: 4384: 4378: 4377: 4357: 4351: 4350: 4314: 4308: 4307: 4305: 4303: 4295: 4284:Retraction Watch 4263: 4239: 4233: 4232: 4208: 4202: 4201: 4181: 4172: 4171: 4126: 4120: 4119: 4113: 4105: 4081: 4075: 4074: 4050: 4044: 4043: 4007: 4001: 4000: 3972: 3966: 3965: 3955: 3923: 3917: 3916: 3906: 3882: 3876: 3875: 3865: 3841: 3830: 3829: 3819: 3795: 3789: 3788: 3778: 3754: 3748: 3747: 3737: 3713: 3707: 3706: 3704: 3703: 3688: 3682: 3681: 3679: 3678: 3663: 3657: 3656: 3654: 3652: 3637: 3631: 3630: 3620: 3588: 3582: 3581: 3571: 3523: 3517: 3516: 3514: 3513: 3498: 3492: 3491: 3455: 3449: 3448: 3412: 3406: 3405: 3377: 3368: 3367: 3349: 3325: 3319: 3318: 3308: 3284: 3275: 3274: 3272: 3271: 3255: 3249: 3248: 3238: 3206: 3200: 3199: 3171: 3154: 3153: 3143: 3111: 3105: 3104: 3076: 3067: 3066: 3064: 3063: 3049: 3040: 3039: 3029: 3005: 2999: 2998: 2980: 2956: 2950: 2949: 2939: 2907: 2901: 2900: 2864: 2851: 2850: 2830: 2824: 2823: 2821: 2820: 2811:. Archived from 2805: 2799: 2798: 2774: 2768: 2767: 2747: 2741: 2740: 2709:Neurobiol. Aging 2704: 2698: 2697: 2672:(12): 993–1002. 2661: 2655: 2654: 2626: 2620: 2619: 2594:(11): CD001869. 2589: 2580: 2574: 2573: 2537: 2531: 2530: 2502: 2496: 2495: 2477: 2471: 2470: 2452: 2441: 2440: 2412: 2406: 2405: 2369: 2363: 2362: 2318: 2312: 2311: 2285: 2261: 2255: 2244: 2238: 2237: 2225: 2219: 2218: 2182: 2176: 2175: 2139: 2120: 2119: 2088:Biol. Psychiatry 2083: 2077: 2076: 2074: 2072: 2052: 2046: 2045: 2035: 2003: 1997: 1996: 1986: 1954: 1945: 1944: 1942: 1940: 1917: 1911: 1910: 1882: 1876: 1875: 1839: 1833: 1832: 1822: 1790: 1784: 1783: 1763: 1757: 1756: 1732: 1726: 1725: 1723: 1721: 1707: 1701: 1700: 1664: 1637: 1636: 1600: 1591: 1590: 1562: 1537: 1536: 1534: 1532: 1513: 1323:Romeo and Juliet 921:Until the 1980s 881:fungal infection 757: 755:Herpes shedding 753: 671:Herpetic sycosis 593:trigeminal nerve 536:Herpetic whitlow 509:Herpes genitalis 456: 455: 411:bipolar disorder 407:herpes keratitis 403:herpetic whitlow 393:Herpes infection 377: 376: 287:Herpetic whitlow 117: 116: 113: 112: 109: 106: 103: 100: 97: 71: 51: 50: 43: 36: 21: 10944: 10943: 10939: 10938: 10937: 10935: 10934: 10933: 10894: 10893: 10892: 10880: 10870: 10868: 10860: 10858: 10849: 10821: 10806: 10762:Ludwig's angina 10723: 10705: 10664:Mouth breathing 10650: 10629: 10450:Pneumoparotitis 10423:Frey's syndrome 10404: 10402:Salivary glands 10387: 10295: 10266: 10245:Phoenix abscess 10078: 10074:hard tissues – 10052: 9974:Hypercementosis 9893:Cementoblastoma 9879: 9842: 9556:Dens evaginatus 9510: 9480: 9432:Denture-related 9417:Plasmoacanthoma 9343:Keratoacanthoma 9164: 9162:Lining of mouth 9143: 9139:Torus palatinus 9100: 9083: 9064:Lingual thyroid 9022:Fissured tongue 9012:Crenated tongue 8988: 8971: 8957:Nasolabial cyst 8942:Herpes labialis 8896: 8883: 8878: 8848: 8843: 8824:Lipschütz ulcer 8794: 8752: 8727: 8692: 8672:Paramyxoviridae 8652: 8623: 8580: 8560: 8489: 8469: 8439: 8415:Milker's nodule 8395: 8347:Monkeypox virus 8299: 8272: 8223: 8178: 8173: 8156: 8151: 8086: 8046: 8040:Skin infections 8037: 8007: 8002: 7981: 7962: 7943: 7934: 7928: 7872:Genital warts ( 7813: 7790: 7765: 7664: 7658: 7628: 7619: 7551: 7544: 7511: 7477:Alopecia areata 7455: 7437: 7423: 7380: 7359: 7335: 7325: 7282: 7241: 7227:Viral exanthems 7205: 7189: 7187: 7177: 7148:Pityriasis alba 7126: 7068: 7010: 6947: 6867: 6863:Zinc deficiency 6793: 6791: 6772: 6700: 6691: 6655: 6646:Nevus sebaceous 6580: 6577: 6547: 6542: 6541: 6518: 6517: 6418: 6393: 6388: 6387: 6377: 6375: 6364: 6360: 6351: 6349: 6340: 6339: 6335: 6326: 6324: 6316: 6315: 6311: 6302: 6300: 6291: 6290: 6286: 6273: 6272: 6268: 6255: 6254: 6250: 6237: 6235: 6226: 6225: 6221: 6211: 6209: 6200: 6199: 6195: 6186: 6184: 6171: 6170: 6166: 6157: 6155: 6142: 6141: 6137: 6122: 6118: 6073: 6069: 6060: 6058: 6054: 6043: 6037: 6033: 5998: 5989: 5960:N. Engl. J. Med 5952: 5948: 5909: 5905: 5860: 5856: 5809: 5805: 5760: 5756: 5701: 5697: 5652: 5648: 5603: 5599: 5568: 5564: 5532: 5528: 5483: 5479: 5442: 5438: 5407: 5403: 5380: 5376: 5331: 5324: 5303: 5296: 5243: 5239: 5192: 5188: 5172: 5171: 5143: 5139: 5102: 5098: 5061: 5057: 5048: 5046: 5038: 5037: 5033: 5001: 4997: 4988: 4986: 4982: 4975: 4971: 4970: 4966: 4956: 4954: 4927: 4923: 4891: 4887: 4850: 4846: 4815: 4811: 4772: 4768: 4745: 4741: 4710: 4706: 4675: 4671: 4636: 4632: 4601: 4597: 4558: 4554: 4530: 4526: 4485:(3): e1000352. 4471: 4467: 4412: 4408: 4385: 4381: 4358: 4354: 4315: 4311: 4297: 4289: 4287: 4264: 4246:(4): CD006700. 4240: 4236: 4215:(1): CD006706. 4209: 4205: 4182: 4175: 4127: 4123: 4107: 4106: 4098: 4082: 4078: 4067: 4051: 4047: 4018:(10): 1809–19. 4008: 4004: 3983:(6): 996–1001. 3973: 3969: 3924: 3920: 3891:Clin Infect Dis 3883: 3879: 3856:(18): 1247–52. 3850:N. Engl. J. Med 3842: 3833: 3796: 3792: 3755: 3751: 3714: 3710: 3701: 3699: 3690: 3689: 3685: 3676: 3674: 3665: 3664: 3660: 3650: 3648: 3639: 3638: 3634: 3603:(13): 1233–40. 3589: 3585: 3534:Wayback Machine 3524: 3520: 3511: 3509: 3500: 3499: 3495: 3456: 3452: 3413: 3409: 3388:(24): 3100–06. 3378: 3371: 3326: 3322: 3293:N. Engl. J. Med 3285: 3278: 3269: 3267: 3256: 3252: 3207: 3203: 3172: 3157: 3126:(13): 7425–33. 3112: 3108: 3077: 3070: 3061: 3059: 3051: 3050: 3043: 3006: 3002: 2957: 2953: 2922:(24): 7228–36. 2908: 2904: 2875:(10): 1577–82. 2865: 2854: 2847: 2831: 2827: 2818: 2816: 2807: 2806: 2802: 2791: 2775: 2771: 2748: 2744: 2705: 2701: 2662: 2658: 2627: 2623: 2587: 2581: 2577: 2538: 2534: 2507:Rev Méd Interne 2503: 2499: 2492: 2478: 2474: 2467: 2453: 2444: 2423:(11): 1440–41. 2417:Clin Infect Dis 2413: 2409: 2370: 2366: 2319: 2315: 2262: 2258: 2245: 2241: 2226: 2222: 2183: 2179: 2140: 2123: 2084: 2080: 2070: 2068: 2053: 2049: 2004: 2000: 1955: 1948: 1938: 1936: 1934: 1918: 1914: 1883: 1879: 1840: 1836: 1791: 1787: 1764: 1760: 1749: 1733: 1729: 1719: 1717: 1709: 1708: 1704: 1665: 1640: 1611:(8): 993–1006. 1601: 1594: 1563: 1540: 1530: 1528: 1515: 1514: 1459: 1454: 1423: 1417: 1405: 1389: 1384: 1356: 1328:Richard Boulton 1311: 1280:against either 1273: 1267: 1252:, or sunlight. 1193: 1153: 1137: 1102:antiviral drugs 1090: 1054: 1036: 1027: 994: 992:Barrier methods 970: 940:family such as 932: 901: 845: 825: 820: 763:15–25% of days 752: 750:Pathophysiology 732: 724:corticosteroids 712: 659: 490:Herpes labialis 454: 452:Types of herpes 387: 366: 315:reside lifelong 299:neonatal herpes 243:viral infection 228:60–95% (adults) 121: 94: 90: 49: 44: 37: 30: 28: 23: 22: 15: 12: 11: 5: 10942: 10932: 10931: 10926: 10924:Viral diseases 10921: 10916: 10911: 10906: 10891: 10890: 10878: 10855: 10854: 10851: 10850: 10848: 10847: 10842: 10837: 10832: 10830:Eagle syndrome 10826: 10823: 10822: 10812: 10811: 10808: 10807: 10805: 10804: 10799: 10794: 10789: 10784: 10779: 10774: 10769: 10764: 10759: 10754: 10752:Cystic hygroma 10749: 10744: 10739: 10734: 10728: 10725: 10724: 10711: 10710: 10707: 10706: 10704: 10703: 10698: 10697: 10696: 10691: 10686: 10681: 10676: 10666: 10661: 10655: 10652: 10651: 10635: 10634: 10631: 10630: 10628: 10627: 10622: 10620:Sialolithiasis 10617: 10612: 10607: 10602: 10597: 10596: 10595: 10590: 10580: 10575: 10574: 10573: 10568: 10563: 10558: 10553: 10551:Adenocarcinoma 10548: 10540: 10535: 10530: 10525: 10520: 10518:Myoepithelioma 10515: 10510: 10505: 10500: 10487: 10482: 10477: 10472: 10467: 10462: 10457: 10452: 10447: 10446: 10445: 10435: 10430: 10425: 10420: 10415: 10409: 10406: 10405: 10393: 10392: 10389: 10388: 10386: 10385: 10384: 10383: 10378: 10368: 10363: 10362: 10361: 10356: 10351: 10346: 10341: 10336: 10331: 10326: 10316: 10311: 10306: 10300: 10297: 10296: 10272: 10271: 10268: 10267: 10265: 10264: 10259: 10254: 10249: 10248: 10247: 10237: 10232: 10227: 10226: 10225: 10220: 10215: 10205: 10200: 10195: 10194: 10193: 10191:Traumatic bone 10188: 10186:Median palatal 10183: 10178: 10170: 10165: 10160: 10155: 10150: 10145: 10140: 10124: 10119: 10114: 10109: 10104: 10099: 10094: 10089: 10083: 10080: 10079: 10058: 10057: 10054: 10053: 10051: 10050: 10045: 10040: 10039: 10038: 10033: 10028: 10018: 10013: 10008: 10003: 9998: 9997: 9996: 9986: 9981: 9979:Hypocementosis 9976: 9971: 9966: 9965: 9964: 9959: 9954: 9944: 9939: 9934: 9929: 9928: 9927: 9922: 9912: 9907: 9902: 9901: 9900: 9890: 9884: 9881: 9880: 9848: 9847: 9844: 9843: 9841: 9840: 9839: 9838: 9833: 9828: 9823: 9813: 9812: 9811: 9801: 9800: 9799: 9794: 9789: 9784: 9774: 9769: 9764: 9759: 9754: 9749: 9744: 9739: 9734: 9729: 9728: 9727: 9717: 9716: 9715: 9713:Neonatal teeth 9705: 9700: 9699: 9698: 9688: 9687: 9686: 9676: 9671: 9666: 9661: 9660: 9659: 9649: 9648: 9647: 9637: 9632: 9627: 9622: 9617: 9612: 9611: 9610: 9600: 9595: 9593:Ectopic enamel 9590: 9585: 9580: 9575: 9570: 9565: 9564: 9563: 9553: 9548: 9543: 9542: 9541: 9531: 9526: 9521: 9515: 9512: 9511: 9486: 9485: 9482: 9481: 9479: 9478: 9473: 9468: 9463: 9462: 9461: 9451: 9446: 9441: 9440: 9439: 9434: 9429: 9419: 9414: 9409: 9408: 9407: 9397: 9396: 9395: 9388:Oral melanosis 9385: 9380: 9379: 9378: 9373: 9368: 9363: 9358: 9353: 9345: 9340: 9327: 9322: 9317: 9312: 9307: 9302: 9297: 9292: 9287: 9282: 9277: 9272: 9267: 9262: 9257: 9252: 9247: 9242: 9237: 9236: 9235: 9225: 9220: 9215: 9210: 9205: 9200: 9195: 9190: 9188:Bohn's nodules 9185: 9180: 9175: 9173:Amalgam tattoo 9169: 9166: 9165: 9149: 9148: 9145: 9144: 9142: 9141: 9136: 9131: 9126: 9121: 9116: 9111: 9105: 9102: 9101: 9089: 9088: 9085: 9084: 9082: 9081: 9076: 9071: 9066: 9061: 9056: 9051: 9050: 9049: 9044: 9039: 9029: 9024: 9019: 9014: 9009: 9004: 8999: 8993: 8990: 8989: 8977: 8976: 8973: 8972: 8970: 8969: 8964: 8959: 8954: 8949: 8944: 8939: 8934: 8929: 8924: 8923: 8922: 8917: 8912: 8901: 8898: 8897: 8885: 8884: 8877: 8876: 8869: 8862: 8854: 8845: 8844: 8842: 8841: 8836: 8831: 8826: 8821: 8816: 8810: 8808: 8804: 8803: 8800: 8799: 8796: 8795: 8793: 8792: 8787: 8782: 8781: 8780: 8775: 8764: 8762: 8759:Picornaviridae 8754: 8753: 8751: 8750: 8745: 8739: 8737: 8729: 8728: 8726: 8725: 8724: 8723: 8717: 8704: 8702: 8694: 8693: 8691: 8690: 8689: 8688: 8677: 8675: 8664: 8658: 8657: 8654: 8653: 8651: 8650: 8649: 8648: 8635: 8633: 8630:Polyomaviridae 8625: 8624: 8622: 8621: 8620: 8619: 8614: 8609: 8601:Parvovirus B19 8596: 8594: 8586: 8585: 8582: 8581: 8579: 8578: 8577: 8576: 8574:Equine sarcoid 8565: 8562: 8561: 8559: 8558: 8553: 8551:Pigmented wart 8548: 8543: 8538: 8533: 8531:Butcher's wart 8528: 8523: 8522: 8521: 8511: 8509:Heck's disease 8506: 8496: 8494: 8483: 8475: 8474: 8471: 8470: 8468: 8467: 8462: 8457: 8447: 8445: 8441: 8440: 8438: 8437: 8432: 8427: 8422: 8417: 8407: 8405: 8397: 8396: 8394: 8393: 8388: 8387: 8386: 8381: 8376: 8371: 8364:Vaccinia virus 8361: 8356: 8355: 8354: 8344: 8343: 8342: 8337: 8326: 8324: 8313: 8305: 8304: 8301: 8300: 8298: 8297: 8296: 8295: 8284: 8282: 8274: 8273: 8271: 8270: 8265: 8264: 8263: 8258: 8239: 8237: 8229: 8228: 8225: 8224: 8222: 8221: 8216: 8211: 8206: 8201: 8196: 8191: 8185: 8183: 8175: 8174: 8172: 8171: 8165: 8163: 8153: 8152: 8150: 8149: 8144: 8139: 8134: 8129: 8127:Genital herpes 8124: 8119: 8114: 8109: 8104: 8099: 8097:Herpes simplex 8093: 8091: 8080: 8069: 8058: 8048: 8047: 8036: 8035: 8028: 8021: 8013: 8004: 8003: 8001: 8000: 7991: 7986: 7978: 7977: 7972: 7967: 7959: 7958: 7953: 7948: 7940: 7938: 7930: 7929: 7927: 7926: 7914: 7902: 7901: 7900: 7893:Herpes simplex 7890: 7878: 7869: 7861: 7860: 7859: 7854: 7849: 7844: 7836: 7823: 7821: 7815: 7814: 7812: 7811: 7806: 7800: 7798: 7792: 7791: 7789: 7788: 7779:Trichomoniasis 7775: 7773: 7767: 7766: 7764: 7763: 7751: 7739: 7727: 7715: 7703: 7687: 7674: 7672: 7666: 7665: 7657: 7656: 7649: 7642: 7634: 7625: 7624: 7621: 7620: 7618: 7617: 7612: 7607: 7602: 7600:Coxsackievirus 7597: 7592: 7587: 7582: 7577: 7572: 7567: 7562: 7556: 7554: 7546: 7545: 7543: 7542: 7537: 7532: 7527: 7521: 7519: 7513: 7512: 7510: 7509: 7504: 7499: 7494: 7489: 7484: 7479: 7474: 7469: 7463: 7461: 7457: 7456: 7454: 7453: 7450: 7448: 7439: 7433: 7432: 7429: 7428: 7425: 7424: 7422: 7421: 7416: 7411: 7406: 7396: 7394: 7390: 7389: 7386: 7385: 7382: 7381: 7379: 7378: 7373: 7367: 7365: 7361: 7360: 7358: 7357: 7352: 7346: 7344: 7337: 7331: 7330: 7327: 7326: 7324: 7323: 7317: 7312: 7310:Gyratum repens 7307: 7302: 7296: 7290: 7288: 7284: 7283: 7281: 7280: 7275: 7270: 7265: 7260: 7255: 7249: 7247: 7243: 7242: 7240: 7239: 7234: 7232:Toxic erythema 7229: 7224: 7222:Drug eruptions 7218: 7216: 7209: 7198: 7191: 7183: 7182: 7179: 7178: 7176: 7175: 7170: 7165: 7160: 7155: 7150: 7145: 7140: 7134: 7132: 7128: 7127: 7125: 7124: 7119: 7114: 7109: 7104: 7099: 7094: 7089: 7084: 7078: 7076: 7070: 7069: 7067: 7066: 7061: 7059:Lichen nitidus 7056: 7051: 7046: 7041: 7036: 7031: 7026: 7020: 7018: 7012: 7011: 7009: 7008: 7003: 6998: 6993: 6988: 6983: 6978: 6973: 6968: 6963: 6961:Herpes simplex 6957: 6955: 6949: 6948: 6946: 6945: 6940: 6935: 6930: 6925: 6920: 6915: 6910: 6904: 6899: 6894: 6889: 6883: 6877: 6875: 6869: 6868: 6866: 6865: 6860: 6855: 6850: 6845: 6840: 6835: 6830: 6825: 6820: 6815: 6810: 6804: 6802: 6795: 6784: 6778: 6777: 6774: 6773: 6771: 6770: 6765: 6760: 6755: 6750: 6745: 6740: 6735: 6730: 6725: 6720: 6715: 6710: 6704: 6702: 6693: 6692: 6690: 6689: 6684: 6679: 6674: 6669: 6663: 6661: 6657: 6656: 6654: 6653: 6648: 6643: 6638: 6633: 6628: 6623: 6618: 6613: 6608: 6603: 6597: 6595: 6586: 6582: 6581: 6576: 6575: 6568: 6561: 6553: 6544: 6543: 6540: 6539: 6527: 6526: 6524: 6520: 6519: 6516: 6515: 6504: 6493: 6462: 6435: 6419: 6414: 6413: 6411: 6410:Classification 6404: 6403: 6392: 6391:External links 6389: 6386: 6385: 6358: 6333: 6309: 6284: 6281:on 2011-10-03. 6266: 6263:on 2008-08-20. 6248: 6219: 6193: 6164: 6135: 6116: 6067: 6031: 5987: 5946: 5919:(8153): 1196. 5903: 5854: 5803: 5754: 5695: 5646: 5617:(5): 1060–66. 5597: 5562: 5537:J. Infect. Dis 5526: 5477: 5436: 5411:J. Infect. Dis 5401: 5374: 5322: 5319:on 2010-02-02. 5294: 5237: 5186: 5137: 5096: 5082:10.1086/343739 5055: 5031: 5006:Health Reports 4995: 4964: 4941:(15): 456–59. 4921: 4885: 4871:10.1086/343739 4858:J. Infect. Dis 4844: 4809: 4766: 4739: 4704: 4679:J. Infect. Dis 4669: 4630: 4595: 4568:(4): 797–803. 4552: 4541:(3): 397–406. 4524: 4479:PLOS Pathogens 4465: 4406: 4395:(8): 1527–34. 4379: 4352: 4309: 4234: 4203: 4173: 4138:(8): 561–568. 4121: 4096: 4076: 4065: 4045: 4002: 3967: 3938:(6661): 1468. 3918: 3904:10.1086/514600 3877: 3831: 3790: 3749: 3708: 3683: 3658: 3632: 3583: 3518: 3493: 3466:(3): 197–202. 3450: 3423:(10): 707–13. 3407: 3369: 3320: 3299:(14): 916–20. 3276: 3250: 3201: 3155: 3106: 3068: 3041: 3027:10.1086/505879 3000: 2951: 2902: 2852: 2845: 2825: 2800: 2789: 2769: 2742: 2699: 2656: 2637:(4): 393–405. 2621: 2575: 2542:Otol. Neurotol 2532: 2497: 2490: 2472: 2465: 2442: 2429:10.1086/592976 2407: 2380:(3): 317–320. 2364: 2329:(2): 209–226. 2313: 2276:(2): 277–287. 2256: 2239: 2220: 2177: 2121: 2078: 2047: 2018:(3): 214–232. 1998: 1946: 1932: 1912: 1877: 1834: 1785: 1758: 1747: 1735:Mosby (2013). 1727: 1702: 1638: 1592: 1538: 1456: 1455: 1453: 1450: 1419:Main article: 1416: 1413: 1404: 1401: 1388: 1385: 1383: 1382:Support groups 1380: 1355: 1352: 1310: 1307: 1269:Main article: 1266: 1263: 1192: 1189: 1152: 1149: 1136: 1133: 1089: 1086: 1053: 1050: 1035: 1032: 1026: 1023: 993: 990: 969: 966: 931: 928: 900: 897: 869:aphthous ulcer 863:, a bacterial 844: 841: 840: 839: 836: 824: 823:Classification 821: 819: 816: 789: 788: 785: 781: 780: 777: 776:HSV-1 genital 773: 772: 771:6–33% of days 769: 765: 764: 761: 760:HSV-2 genital 751: 748: 731: 728: 711: 708: 658: 655: 652: 651: 642: 619: 613: 612: 603: 585: 575: 574: 565: 546:contact sports 542: 532: 531: 522: 511: 505: 504: 495: 492: 486: 485: 476: 473: 467: 466: 463: 460: 453: 450: 438:seroconversion 386: 383: 365: 362: 311:sensory nerves 255:genital herpes 245:caused by the 235:Herpes simplex 230: 229: 226: 222: 221: 207: 201: 200: 190: 184: 183: 177: 171: 170: 164: 160: 159: 156: 152: 151: 141: 135: 134: 129: 123: 122: 120: 119: 87: 85: 81: 80: 73: 72: 64: 63: 62:Herpes simplex 60: 56: 55: 47: 26: 18:Herpes simplex 9: 6: 4: 3: 2: 10941: 10930: 10927: 10925: 10922: 10920: 10917: 10915: 10912: 10910: 10907: 10905: 10902: 10901: 10899: 10889: 10884: 10879: 10877: 10867: 10866: 10863: 10846: 10843: 10841: 10838: 10836: 10833: 10831: 10828: 10827: 10824: 10817: 10813: 10803: 10800: 10798: 10795: 10793: 10790: 10788: 10785: 10783: 10780: 10778: 10775: 10773: 10770: 10768: 10765: 10763: 10760: 10758: 10755: 10753: 10750: 10748: 10745: 10743: 10740: 10738: 10735: 10733: 10732:Actinomycosis 10730: 10729: 10726: 10722: 10716: 10712: 10702: 10699: 10695: 10692: 10690: 10687: 10685: 10682: 10680: 10677: 10675: 10672: 10671: 10670: 10667: 10665: 10662: 10660: 10657: 10656: 10653: 10649: 10645: 10640: 10636: 10626: 10623: 10621: 10618: 10616: 10613: 10611: 10610:Sialodochitis 10608: 10606: 10603: 10601: 10598: 10594: 10591: 10589: 10586: 10585: 10584: 10581: 10579: 10576: 10572: 10569: 10567: 10564: 10562: 10559: 10557: 10554: 10552: 10549: 10547: 10544: 10541: 10539: 10536: 10534: 10531: 10529: 10526: 10524: 10521: 10519: 10516: 10514: 10511: 10509: 10506: 10504: 10501: 10499: 10496: 10493: 10492: 10491: 10488: 10486: 10483: 10481: 10478: 10476: 10473: 10471: 10468: 10466: 10463: 10461: 10458: 10456: 10453: 10451: 10448: 10444: 10441: 10440: 10439: 10436: 10434: 10431: 10429: 10426: 10424: 10421: 10419: 10416: 10414: 10411: 10410: 10407: 10403: 10398: 10394: 10382: 10379: 10377: 10374: 10373: 10372: 10369: 10367: 10364: 10360: 10357: 10355: 10352: 10350: 10347: 10345: 10342: 10340: 10337: 10335: 10332: 10330: 10327: 10325: 10322: 10321: 10320: 10317: 10315: 10312: 10310: 10307: 10305: 10302: 10301: 10298: 10294: 10290: 10289:malocclusions 10286: 10282: 10277: 10273: 10263: 10260: 10258: 10257:Stafne defect 10255: 10253: 10250: 10246: 10243: 10242: 10241: 10238: 10236: 10233: 10231: 10228: 10224: 10221: 10219: 10216: 10214: 10211: 10210: 10209: 10208:Osteonecrosis 10206: 10204: 10203:Osteomyelitis 10201: 10199: 10196: 10192: 10189: 10187: 10184: 10182: 10179: 10177: 10174: 10171: 10169: 10166: 10164: 10161: 10159: 10156: 10154: 10151: 10149: 10146: 10144: 10141: 10139: 10136: 10134: 10130: 10129: 10128: 10125: 10123: 10120: 10118: 10115: 10113: 10110: 10108: 10105: 10103: 10100: 10098: 10095: 10093: 10090: 10088: 10085: 10084: 10081: 10077: 10076:Bones of jaws 10073: 10069: 10063: 10059: 10049: 10046: 10044: 10041: 10037: 10034: 10032: 10029: 10027: 10024: 10023: 10022: 10021:Periodontitis 10019: 10017: 10014: 10012: 10009: 10007: 10004: 10002: 10001:Pericoronitis 9999: 9995: 9992: 9991: 9990: 9987: 9985: 9982: 9980: 9977: 9975: 9972: 9970: 9967: 9963: 9960: 9958: 9957:Granulomatous 9955: 9953: 9950: 9949: 9948: 9945: 9943: 9940: 9938: 9935: 9933: 9930: 9926: 9923: 9921: 9918: 9917: 9916: 9913: 9911: 9910:Eruption cyst 9908: 9906: 9903: 9899: 9896: 9895: 9894: 9891: 9889: 9886: 9885: 9882: 9878: 9874: 9870: 9866: 9862: 9858: 9853: 9849: 9837: 9834: 9832: 9829: 9827: 9824: 9822: 9819: 9818: 9817: 9814: 9810: 9807: 9806: 9805: 9802: 9798: 9795: 9793: 9790: 9788: 9785: 9783: 9780: 9779: 9778: 9775: 9773: 9770: 9768: 9765: 9763: 9760: 9758: 9755: 9753: 9750: 9748: 9745: 9743: 9740: 9738: 9737:Pulp necrosis 9735: 9733: 9730: 9726: 9723: 9722: 9721: 9718: 9714: 9711: 9710: 9709: 9706: 9704: 9701: 9697: 9696:Dens in dente 9694: 9693: 9692: 9689: 9685: 9682: 9681: 9680: 9677: 9675: 9672: 9670: 9667: 9665: 9662: 9658: 9655: 9654: 9653: 9650: 9646: 9643: 9642: 9641: 9638: 9636: 9633: 9631: 9628: 9626: 9623: 9621: 9618: 9616: 9613: 9609: 9606: 9605: 9604: 9601: 9599: 9596: 9594: 9591: 9589: 9588:Discoloration 9586: 9584: 9581: 9579: 9576: 9574: 9571: 9569: 9566: 9562: 9559: 9558: 9557: 9554: 9552: 9549: 9547: 9544: 9540: 9537: 9536: 9535: 9532: 9530: 9527: 9525: 9522: 9520: 9517: 9516: 9513: 9508: 9504: 9500: 9496: 9491: 9487: 9477: 9474: 9472: 9469: 9467: 9464: 9460: 9457: 9456: 9455: 9452: 9450: 9447: 9445: 9442: 9438: 9435: 9433: 9430: 9428: 9425: 9424: 9423: 9420: 9418: 9415: 9413: 9410: 9406: 9403: 9402: 9401: 9398: 9394: 9391: 9390: 9389: 9386: 9384: 9381: 9377: 9374: 9372: 9369: 9367: 9364: 9362: 9359: 9357: 9354: 9352: 9349: 9346: 9344: 9341: 9339: 9336: 9333: 9332: 9331: 9328: 9326: 9323: 9321: 9318: 9316: 9313: 9311: 9308: 9306: 9303: 9301: 9298: 9296: 9295:Lichen planus 9293: 9291: 9288: 9286: 9283: 9281: 9278: 9276: 9273: 9271: 9270:Herpes zoster 9268: 9266: 9263: 9261: 9258: 9256: 9253: 9251: 9248: 9246: 9245:Fordyce spots 9243: 9241: 9238: 9234: 9231: 9230: 9229: 9226: 9224: 9223:Erythroplakia 9221: 9219: 9216: 9214: 9211: 9209: 9206: 9204: 9201: 9199: 9196: 9194: 9191: 9189: 9186: 9184: 9181: 9179: 9176: 9174: 9171: 9170: 9167: 9163: 9159: 9154: 9150: 9140: 9137: 9135: 9132: 9130: 9127: 9125: 9122: 9120: 9117: 9115: 9112: 9110: 9107: 9106: 9103: 9099: 9094: 9090: 9080: 9077: 9075: 9072: 9070: 9067: 9065: 9062: 9060: 9057: 9055: 9052: 9048: 9045: 9043: 9040: 9038: 9035: 9034: 9033: 9030: 9028: 9025: 9023: 9020: 9018: 9015: 9013: 9010: 9008: 9007:Caviar tongue 9005: 9003: 9000: 8998: 8997:Ankyloglossia 8995: 8994: 8991: 8987: 8982: 8978: 8968: 8965: 8963: 8962:Sun poisoning 8960: 8958: 8955: 8953: 8950: 8948: 8945: 8943: 8940: 8938: 8935: 8933: 8930: 8928: 8925: 8921: 8918: 8916: 8913: 8911: 8908: 8907: 8906: 8903: 8902: 8899: 8895: 8890: 8886: 8882: 8875: 8870: 8868: 8863: 8861: 8856: 8855: 8852: 8840: 8837: 8835: 8832: 8830: 8827: 8825: 8822: 8820: 8817: 8815: 8812: 8811: 8809: 8805: 8791: 8788: 8786: 8783: 8779: 8776: 8774: 8771: 8770: 8769: 8766: 8765: 8763: 8761: 8760: 8755: 8749: 8746: 8744: 8741: 8740: 8738: 8736: 8735: 8730: 8721: 8718: 8716: 8713: 8712: 8711: 8710: 8709:Rubella virus 8706: 8705: 8703: 8701: 8700: 8699:Matonaviridae 8695: 8687: 8684: 8683: 8682: 8679: 8678: 8676: 8674: 8673: 8668: 8665: 8663: 8659: 8647: 8644: 8643: 8642: 8641: 8637: 8636: 8634: 8632: 8631: 8626: 8618: 8615: 8613: 8610: 8608: 8605: 8604: 8603: 8602: 8598: 8597: 8595: 8593: 8592: 8587: 8575: 8572: 8571: 8570: 8567: 8566: 8563: 8557: 8554: 8552: 8549: 8547: 8546:Verruca plana 8544: 8542: 8539: 8537: 8534: 8532: 8529: 8527: 8524: 8520: 8517: 8516: 8515: 8512: 8510: 8507: 8505: 8501: 8498: 8497: 8495: 8492: 8487: 8484: 8482: 8481: 8476: 8466: 8463: 8461: 8458: 8456: 8452: 8449: 8448: 8446: 8442: 8436: 8433: 8431: 8428: 8426: 8423: 8421: 8418: 8416: 8412: 8409: 8408: 8406: 8404: 8403: 8398: 8392: 8389: 8385: 8382: 8380: 8377: 8375: 8372: 8370: 8367: 8366: 8365: 8362: 8360: 8357: 8353: 8350: 8349: 8348: 8345: 8341: 8338: 8336: 8333: 8332: 8331: 8328: 8327: 8325: 8323: 8322: 8317: 8314: 8312: 8311: 8306: 8294: 8291: 8290: 8289: 8286: 8285: 8283: 8281: 8280: 8275: 8269: 8266: 8262: 8259: 8257: 8254: 8253: 8252: 8251: 8246: 8245: 8241: 8240: 8238: 8236: 8235: 8230: 8220: 8217: 8215: 8212: 8210: 8207: 8205: 8202: 8200: 8197: 8195: 8194:Herpes zoster 8192: 8190: 8187: 8186: 8184: 8181: 8176: 8170: 8167: 8166: 8164: 8161: 8160: 8154: 8148: 8145: 8143: 8140: 8138: 8135: 8133: 8130: 8128: 8125: 8123: 8120: 8118: 8115: 8113: 8110: 8108: 8105: 8103: 8100: 8098: 8095: 8094: 8092: 8089: 8084: 8081: 8079: 8078: 8073: 8070: 8068: 8067: 8066:Herpesviridae 8062: 8059: 8057: 8053: 8049: 8045: 8041: 8034: 8029: 8027: 8022: 8020: 8015: 8014: 8011: 7999: 7995: 7992: 7990: 7987: 7984: 7980: 7979: 7976: 7973: 7971: 7968: 7965: 7961: 7960: 7957: 7954: 7952: 7949: 7946: 7942: 7941: 7939: 7937: 7931: 7924: 7923: 7918: 7915: 7912: 7911: 7906: 7903: 7899: 7896: 7895: 7894: 7891: 7888: 7887: 7882: 7879: 7877: 7875: 7870: 7868: 7866: 7862: 7858: 7855: 7853: 7850: 7848: 7845: 7843: 7840: 7839: 7837: 7834: 7833: 7828: 7825: 7824: 7822: 7820: 7816: 7810: 7807: 7805: 7802: 7801: 7799: 7797: 7793: 7786: 7785: 7780: 7777: 7776: 7774: 7772: 7768: 7761: 7760: 7755: 7752: 7749: 7748: 7743: 7740: 7737: 7736: 7731: 7728: 7725: 7724: 7719: 7716: 7713: 7712: 7707: 7704: 7701: 7700: 7695: 7691: 7688: 7685: 7684: 7679: 7676: 7675: 7673: 7671: 7667: 7662: 7655: 7650: 7648: 7643: 7641: 7636: 7635: 7632: 7616: 7613: 7611: 7608: 7606: 7603: 7601: 7598: 7596: 7593: 7591: 7588: 7586: 7583: 7581: 7578: 7576: 7573: 7571: 7570:Lichen planus 7568: 7566: 7563: 7561: 7558: 7557: 7555: 7553: 7547: 7541: 7538: 7536: 7533: 7531: 7528: 7526: 7525:Onychomycosis 7523: 7522: 7520: 7518: 7514: 7508: 7505: 7503: 7500: 7498: 7495: 7493: 7490: 7488: 7487:Tinea capitis 7485: 7483: 7480: 7478: 7475: 7473: 7470: 7468: 7465: 7464: 7462: 7458: 7452: 7451: 7449: 7447: 7443: 7440: 7436:Miscellaneous 7434: 7420: 7417: 7415: 7412: 7410: 7407: 7405: 7401: 7398: 7397: 7395: 7391: 7377: 7374: 7372: 7369: 7368: 7366: 7362: 7356: 7353: 7351: 7348: 7347: 7345: 7341: 7338: 7334:Nonblanchable 7332: 7321: 7318: 7316: 7313: 7311: 7308: 7306: 7303: 7301: 7297: 7295: 7292: 7291: 7289: 7285: 7279: 7276: 7274: 7271: 7269: 7266: 7264: 7261: 7259: 7256: 7254: 7251: 7250: 7248: 7244: 7238: 7235: 7233: 7230: 7228: 7225: 7223: 7220: 7219: 7217: 7213: 7210: 7208: 7202: 7199: 7195: 7192: 7184: 7174: 7171: 7169: 7166: 7164: 7161: 7159: 7156: 7154: 7151: 7149: 7146: 7144: 7141: 7139: 7136: 7135: 7133: 7131:Hypopigmented 7129: 7123: 7120: 7118: 7115: 7113: 7110: 7108: 7105: 7103: 7100: 7098: 7095: 7093: 7090: 7088: 7085: 7083: 7082:Acne vulgaris 7080: 7079: 7077: 7075: 7071: 7065: 7062: 7060: 7057: 7055: 7052: 7050: 7047: 7045: 7042: 7040: 7037: 7035: 7034:Lichen planus 7032: 7030: 7027: 7025: 7022: 7021: 7019: 7017: 7013: 7007: 7004: 7002: 6999: 6997: 6994: 6992: 6989: 6987: 6984: 6982: 6979: 6977: 6974: 6972: 6969: 6967: 6966:Herpes zoster 6964: 6962: 6959: 6958: 6956: 6954: 6950: 6944: 6941: 6939: 6938:Parapsoriasis 6936: 6934: 6931: 6929: 6926: 6924: 6921: 6919: 6916: 6914: 6911: 6908: 6905: 6903: 6900: 6898: 6895: 6893: 6890: 6888: 6884: 6882: 6879: 6878: 6876: 6874: 6870: 6864: 6861: 6859: 6856: 6854: 6851: 6849: 6846: 6844: 6841: 6839: 6836: 6834: 6831: 6829: 6826: 6824: 6821: 6819: 6816: 6814: 6811: 6809: 6806: 6805: 6803: 6799: 6796: 6788: 6785: 6783: 6779: 6769: 6766: 6764: 6761: 6759: 6756: 6754: 6751: 6749: 6746: 6744: 6741: 6739: 6736: 6734: 6731: 6729: 6726: 6724: 6721: 6719: 6716: 6714: 6711: 6709: 6706: 6705: 6703: 6698: 6694: 6688: 6685: 6683: 6680: 6678: 6675: 6673: 6670: 6668: 6665: 6664: 6662: 6658: 6652: 6649: 6647: 6644: 6642: 6639: 6637: 6634: 6632: 6629: 6627: 6624: 6622: 6619: 6617: 6614: 6612: 6609: 6607: 6604: 6602: 6599: 6598: 6596: 6594: 6590: 6587: 6583: 6574: 6569: 6567: 6562: 6560: 6555: 6554: 6551: 6538: 6534: 6533: 6529: 6528: 6525: 6521: 6514: 6510: 6509: 6505: 6503: 6499: 6498: 6494: 6492: 6488: 6484: 6480: 6476: 6472: 6471: 6467: 6463: 6461: 6457: 6453: 6449: 6445: 6444: 6440: 6436: 6434: 6430: 6429: 6425: 6421: 6420: 6417: 6412: 6408: 6402: 6398: 6395: 6394: 6373: 6369: 6362: 6347: 6343: 6337: 6323: 6319: 6313: 6298: 6294: 6288: 6280: 6276: 6270: 6262: 6258: 6252: 6245: 6233: 6229: 6228:"Our History" 6223: 6207: 6203: 6197: 6182: 6178: 6174: 6168: 6153: 6149: 6145: 6139: 6131: 6127: 6120: 6112: 6108: 6103: 6098: 6094: 6090: 6086: 6082: 6078: 6071: 6057:on 2008-12-16 6053: 6049: 6042: 6035: 6027: 6023: 6019: 6015: 6012:(2): 230–38. 6011: 6007: 6003: 5996: 5994: 5992: 5983: 5979: 5974: 5969: 5966:(7): 444–49. 5965: 5961: 5957: 5950: 5942: 5938: 5934: 5930: 5926: 5922: 5918: 5914: 5907: 5899: 5895: 5890: 5885: 5881: 5877: 5874:(6): 643–50. 5873: 5869: 5865: 5858: 5850: 5846: 5842: 5838: 5834: 5830: 5826: 5822: 5818: 5814: 5807: 5799: 5795: 5790: 5785: 5781: 5777: 5774:(5): 819–23. 5773: 5769: 5765: 5758: 5750: 5746: 5742: 5738: 5734: 5730: 5726: 5722: 5719:(1): 247–53. 5718: 5714: 5710: 5706: 5699: 5691: 5687: 5682: 5677: 5673: 5669: 5666:(3): 229–33. 5665: 5661: 5657: 5650: 5642: 5638: 5633: 5628: 5624: 5620: 5616: 5612: 5608: 5601: 5593: 5589: 5585: 5581: 5578:(7646): 572. 5577: 5573: 5566: 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3261: 3254: 3246: 3242: 3237: 3232: 3228: 3224: 3221:(4): 662–67. 3220: 3216: 3212: 3205: 3197: 3193: 3189: 3185: 3181: 3177: 3170: 3168: 3166: 3164: 3162: 3160: 3151: 3147: 3142: 3137: 3133: 3129: 3125: 3121: 3117: 3110: 3102: 3098: 3094: 3090: 3087:(4): 825–39. 3086: 3082: 3075: 3073: 3058: 3054: 3048: 3046: 3037: 3033: 3028: 3023: 3020:(4): 420–27. 3019: 3015: 3011: 3004: 2996: 2992: 2988: 2984: 2979: 2974: 2970: 2966: 2962: 2955: 2947: 2943: 2938: 2933: 2929: 2925: 2921: 2917: 2913: 2906: 2898: 2894: 2890: 2886: 2882: 2878: 2874: 2870: 2863: 2861: 2859: 2857: 2848: 2842: 2838: 2837: 2829: 2814: 2810: 2804: 2796: 2792: 2786: 2782: 2781: 2773: 2765: 2761: 2757: 2753: 2746: 2738: 2734: 2730: 2726: 2722: 2718: 2715:(4): 457–65. 2714: 2710: 2703: 2695: 2691: 2687: 2683: 2679: 2675: 2671: 2667: 2660: 2652: 2648: 2644: 2640: 2636: 2632: 2625: 2617: 2613: 2609: 2605: 2601: 2597: 2593: 2586: 2579: 2571: 2567: 2563: 2559: 2555: 2551: 2548:(1): 109–13. 2547: 2543: 2536: 2528: 2524: 2520: 2516: 2513:(9): 769–75. 2512: 2509:(in French). 2508: 2501: 2493: 2487: 2483: 2476: 2468: 2462: 2458: 2451: 2449: 2447: 2438: 2434: 2430: 2426: 2422: 2418: 2411: 2403: 2399: 2395: 2391: 2387: 2383: 2379: 2375: 2368: 2360: 2356: 2352: 2348: 2344: 2340: 2336: 2332: 2328: 2324: 2317: 2309: 2305: 2301: 2297: 2293: 2289: 2284: 2279: 2275: 2271: 2267: 2260: 2254: 2250: 2249: 2243: 2235: 2231: 2224: 2216: 2212: 2208: 2204: 2200: 2196: 2192: 2188: 2181: 2173: 2169: 2165: 2161: 2157: 2153: 2149: 2145: 2138: 2136: 2134: 2132: 2130: 2128: 2126: 2117: 2113: 2109: 2105: 2101: 2097: 2094:(6): 588–93. 2093: 2089: 2082: 2066: 2062: 2058: 2055:Reese, Vail. 2051: 2043: 2039: 2034: 2029: 2025: 2021: 2017: 2013: 2009: 2002: 1994: 1990: 1985: 1980: 1976: 1972: 1968: 1964: 1960: 1953: 1951: 1935: 1929: 1925: 1924: 1916: 1908: 1904: 1900: 1896: 1893:(4): 601–14. 1892: 1888: 1881: 1873: 1869: 1865: 1861: 1857: 1853: 1849: 1845: 1838: 1830: 1826: 1821: 1816: 1812: 1808: 1804: 1800: 1796: 1789: 1781: 1777: 1774:(3): 193–06. 1773: 1769: 1762: 1754: 1750: 1748:9780323112581 1744: 1740: 1739: 1731: 1716: 1712: 1706: 1698: 1694: 1690: 1686: 1682: 1678: 1674: 1670: 1663: 1661: 1659: 1657: 1655: 1653: 1651: 1649: 1647: 1645: 1643: 1634: 1630: 1626: 1622: 1618: 1614: 1610: 1606: 1599: 1597: 1588: 1584: 1580: 1576: 1573:(2): 265–80. 1572: 1568: 1561: 1559: 1557: 1555: 1553: 1551: 1549: 1547: 1545: 1543: 1526: 1522: 1518: 1512: 1510: 1508: 1506: 1504: 1502: 1500: 1498: 1496: 1494: 1492: 1490: 1488: 1486: 1484: 1482: 1480: 1478: 1476: 1474: 1472: 1470: 1468: 1466: 1464: 1462: 1457: 1449: 1447: 1443: 1438: 1435: 1431: 1426: 1422: 1412: 1410: 1400: 1398: 1394: 1387:United States 1379: 1377: 1372: 1369: 1365: 1361: 1351: 1348: 1344: 1340: 1335: 1333: 1329: 1325: 1324: 1319: 1314: 1306: 1303: 1300: 1296: 1292: 1290: 1285: 1283: 1282:viral species 1279: 1272: 1262: 1259: 1253: 1251: 1247: 1242: 1240: 1236: 1232: 1227: 1225: 1221: 1216: 1214: 1210: 1207:of a nerve's 1206: 1202: 1198: 1188: 1186: 1182: 1178: 1174: 1170: 1166: 1162: 1158: 1148: 1146: 1142: 1132: 1130: 1125: 1123: 1119: 1115: 1111: 1108:(acyclovir), 1107: 1103: 1094: 1085: 1083: 1079: 1075: 1071: 1067: 1063: 1059: 1049: 1045: 1042: 1031: 1022: 1020: 1016: 1012: 1008: 1004: 999: 998:female condom 989: 987: 982: 978: 976: 965: 963: 959: 955: 951: 947: 943: 942:herpes zoster 939: 938: 937:herpesviridae 927: 924: 919: 917: 913: 909: 905: 896: 894: 890: 886: 885:lichen planus 882: 876: 874: 870: 866: 862: 858: 855: 851: 837: 834: 830: 829: 828: 815: 813: 808: 803: 800: 795: 786: 783: 782: 778: 775: 774: 770: 767: 766: 762: 759: 758: 747: 745: 741: 737: 727: 725: 721: 717: 707: 705: 704:hair follicle 700: 698: 694: 691:and eyelids ( 690: 686: 682: 680: 676: 672: 667: 663: 647: 643: 640: 636: 632: 628: 624: 620: 618: 615: 614: 608: 604: 601: 597: 594: 590: 589:temporal lobe 586: 584: 580: 577: 576: 570: 566: 563: 559: 555: 551: 547: 543: 541: 537: 534: 533: 527: 523: 520: 516: 512: 510: 507: 506: 500: 496: 493: 491: 488: 487: 481: 477: 474: 472: 469: 468: 465:Illustration 464: 461: 458: 457: 449: 447: 442: 439: 435: 431: 427: 426:immune system 422: 420: 416: 412: 408: 404: 400: 391: 382: 380: 371: 361: 357: 355: 351: 347: 343: 339: 335: 330: 328: 324: 323:viral culture 320: 316: 312: 308: 302: 300: 296: 292: 288: 284: 282: 277: 275: 271: 267: 262: 261:also exist. 260: 256: 252: 248: 244: 240: 236: 227: 223: 219: 215: 211: 208: 206: 202: 199: 198:viral culture 195: 191: 189: 185: 181: 178: 176: 172: 168: 165: 161: 157: 153: 150: 146: 142: 140: 136: 133: 130: 128: 124: 115: 89: 88: 86: 84:Pronunciation 82: 78: 74: 70: 65: 61: 57: 52: 46: 41: 34: 33:Herpesviridae 19: 10720: 10647: 10583:Sialadenitis 10542: 10494: 10359:Scissor bite 10354:Retrognathia 10339:Overeruption 10319:Malocclusion 10292: 10172: 10131: 10122:Micrognathia 10075: 10066:Periapical, 9952:Desquamative 9876: 9857:Periodontium 9831:Acid erosion 9772:Taurodontism 9703:Open contact 9615:Enamel pearl 9583:Dilaceration 9546:Concrescence 9347: 9334: 9161: 9114:Cleft palate 9074:Microglossia 9069:Macroglossia 9054:Glossoptosis 8952:Microcheilia 8947:Macrocheilia 8757: 8732: 8707: 8697: 8670: 8638: 8628: 8599: 8591:Parvoviridae 8589: 8514:Genital wart 8504:plantar wart 8478: 8451:Yatapoxvirus 8425:Pseudocowpox 8411:Farmyard pox 8400: 8319: 8308: 8277: 8250:Roseolovirus 8248: 8242: 8232: 8157: 8116: 8096: 8075: 8064: 7982: 7970:Epididymitis 7963: 7944: 7936:inflammation 7920: 7908: 7892: 7884: 7873: 7864: 7830: 7782: 7757: 7745: 7733: 7721: 7709: 7697: 7681: 7540:Ingrown nail 7112:Dermatophyte 7107:Gonococcemia 7092:Folliculitis 6960: 6733:Neurofibroma 6701:subcutaneous 6530: 6506: 6495: 6464: 6437: 6422: 6376:. Retrieved 6361: 6350:. Retrieved 6348:. 2022-09-27 6345: 6336: 6325:. Retrieved 6321: 6312: 6301:. Retrieved 6287: 6279:the original 6269: 6261:the original 6251: 6243: 6236:. Retrieved 6222: 6210:. Retrieved 6196: 6185:. Retrieved 6176: 6167: 6156:. Retrieved 6147: 6138: 6130:the original 6119: 6087:(1): 42–44. 6084: 6080: 6070: 6059:. Retrieved 6052:the original 6047: 6034: 6009: 6005: 5963: 5959: 5949: 5916: 5912: 5906: 5871: 5867: 5857: 5816: 5812: 5806: 5771: 5767: 5757: 5716: 5712: 5708: 5704: 5698: 5663: 5659: 5649: 5614: 5611:J. Bacteriol 5610: 5600: 5575: 5571: 5565: 5540: 5536: 5529: 5494: 5490: 5480: 5453: 5449: 5439: 5414: 5410: 5404: 5387: 5383: 5377: 5342: 5338: 5317:the original 5310: 5254: 5250: 5240: 5206:(2): 94–96. 5203: 5199: 5189: 5175:cite journal 5150: 5146: 5140: 5113: 5109: 5099: 5072: 5069:J Infect Dis 5068: 5058: 5047:. Retrieved 5043: 5034: 5012:(4): 10–15. 5009: 5005: 4998: 4987:. Retrieved 4967: 4955:. Retrieved 4938: 4934: 4924: 4899: 4895: 4888: 4861: 4857: 4847: 4822: 4819:Annu Rev Med 4818: 4812: 4782:(1): 42–48. 4779: 4775: 4769: 4752: 4748: 4742: 4717: 4713: 4707: 4682: 4678: 4672: 4647: 4643: 4633: 4608: 4604: 4598: 4565: 4562:J. Dent. Res 4561: 4555: 4538: 4534: 4527: 4482: 4478: 4468: 4423: 4419: 4409: 4392: 4388: 4382: 4368:(2): 38–41. 4365: 4361: 4355: 4322: 4318: 4312: 4298:{{ 4290:{{ 4283: 4281:,   4243: 4237: 4212: 4206: 4189: 4185: 4135: 4131: 4124: 4086: 4079: 4055: 4048: 4015: 4011: 4005: 3980: 3976: 3970: 3935: 3931: 3921: 3894: 3890: 3880: 3853: 3849: 3807: 3803: 3793: 3766: 3763:N Engl J Med 3762: 3752: 3725: 3721: 3711: 3700:. Retrieved 3686: 3675:. Retrieved 3661: 3649:. Retrieved 3645:the original 3635: 3600: 3596: 3586: 3551: 3547: 3537: 3521: 3510:. Retrieved 3496: 3463: 3459: 3453: 3420: 3416: 3410: 3385: 3381: 3340:(1): 11–20. 3337: 3334:N Engl J Med 3333: 3323: 3296: 3292: 3268:. Retrieved 3264:the original 3253: 3218: 3214: 3204: 3179: 3175: 3123: 3119: 3109: 3084: 3080: 3060:. Retrieved 3056: 3017: 3014:J Infect Dis 3013: 3003: 2971:(1): 13–22. 2968: 2964: 2954: 2919: 2916:FEBS Journal 2915: 2905: 2872: 2868: 2835: 2828: 2817:. Retrieved 2813:the original 2803: 2779: 2772: 2758:(3): 64–68. 2755: 2751: 2745: 2712: 2708: 2702: 2669: 2665: 2659: 2634: 2630: 2624: 2591: 2578: 2545: 2541: 2535: 2510: 2506: 2500: 2481: 2475: 2456: 2420: 2416: 2410: 2377: 2373: 2367: 2326: 2322: 2316: 2273: 2269: 2259: 2246: 2242: 2234:The Guardian 2233: 2223: 2193:(1): 25–30. 2190: 2186: 2180: 2147: 2143: 2091: 2087: 2081: 2071:22 September 2069:. Retrieved 2065:the original 2060: 2050: 2015: 2011: 2001: 1966: 1962: 1937:. Retrieved 1922: 1915: 1890: 1886: 1880: 1847: 1843: 1837: 1802: 1798: 1788: 1771: 1767: 1761: 1737: 1730: 1718:. Retrieved 1714: 1705: 1672: 1668: 1608: 1604: 1570: 1566: 1529:. Retrieved 1520: 1439: 1427: 1424: 1406: 1392: 1390: 1373: 1357: 1336: 1331: 1321: 1315: 1312: 1304: 1301: 1297: 1293: 1286: 1274: 1265:Epidemiology 1258:asymptomatic 1254: 1246:radiotherapy 1243: 1235:menstruation 1228: 1217: 1194: 1154: 1139:A number of 1138: 1126: 1110:valaciclovir 1099: 1055: 1046: 1037: 1028: 1019:microbicides 1015:valaciclovir 1006: 995: 983: 979: 974: 971: 935: 933: 920: 902: 877: 846: 826: 804: 796: 792: 744:lipoproteins 733: 716:Bell's palsy 713: 710:Bell's palsy 701: 683: 660: 462:Description 443: 423: 396: 378: 367: 358: 354:valaciclovir 331: 303: 285: 278: 263: 238: 234: 233: 214:valaciclovir 175:Risk factors 45: 10777:Microstomia 10767:Macrostomia 10757:Gnathophyma 10674:Catathrenia 10669:Sleep apnea 10600:Sialectasis 10143:Dentigerous 10133:Odontogenic 9962:Plasma cell 9898:Gigantiform 9674:Microdontia 9664:Macrodontia 9635:Hyperdontia 9330:Oral cancer 9290:Leukoplakia 9198:Candidiasis 9158:Oral mucosa 9079:Rhabdomyoma 9059:Hypoglossia 8920:Plasma cell 8734:Togaviridae 7975:Prostatitis 7881:Hepatitis B 7832:HIV-1/HIV-2 7706:Donovanosis 7595:Herpesvirus 7575:Leukoplakia 7400:Scleroderma 7287:Specialized 7215:Generalized 7190:involvement 7102:Candidiasis 6794:involvement 6768:Myxoid cyst 6616:Acrochordon 4186:J Fam Pract 3525:McNeil DG. 1850:(12): 414. 1720:21 November 1669:Pediatr Rev 1531:31 December 1397:World War I 1224:paresthesia 1118:penciclovir 1114:famciclovir 1066:paracetamol 1003:dental dams 923:serological 912:skin biopsy 843:Examination 835:infections. 787:1% of days 784:HSV-2 oral 779:5% of days 768:HSV-1 oral 689:conjunctiva 623:odynophagia 446:subclinical 346:Paracetamol 281:lymph nodes 259:other forms 251:oral herpes 218:paracetamol 149:lymph nodes 77:Oral herpes 59:Other names 10898:Categories 10737:Angioedema 10543:Malignant: 10523:Oncocytoma 10349:Prognathia 10138:periapical 10117:Microgenia 10068:mandibular 10026:Aggressive 9947:Gingivitis 9888:Cementicle 9826:Abfraction 9816:Tooth wear 9809:Edentulism 9804:Tooth loss 9757:Resorption 9742:Pulp polyp 9725:Pulp stone 9669:Meth mouth 9640:Hypodontia 9630:Gemination 9561:Talon cusp 9454:Ulceration 9422:Stomatitis 9400:Pemphigoid 9348:Malignant: 9300:Linea alba 9285:Leukoedema 9265:Herpangina 9233:Giant-cell 8778:Herpangina 8391:Buffalopox 8310:Poxviridae 8189:Chickenpox 7994:Urethritis 7951:Cervicitis 7922:Zika virus 7917:Zika fever 7804:Crab louse 7535:Paronychia 7376:Vasculitis 7300:Multiforme 7298:Erythema ( 7253:Cellulitis 7204:Blanchable 6953:Blistering 6943:Ichthyosis 6801:Eczematous 6713:Hemangioma 6508:DiseasesDB 6378:22 October 6352:2022-12-11 6327:2022-12-11 6303:2017-02-20 6238:19 October 6187:2017-02-20 6158:2017-02-20 6061:2008-09-10 6006:Pediatrics 5049:2017-02-20 4989:2012-02-19 4825:: 381–95. 3702:2011-10-01 3677:2011-10-01 3512:2014-01-30 3270:2011-04-12 3062:2021-03-06 2819:2008-02-24 1805:: 88–101. 1452:References 1360:depression 1278:antibodies 1173:monolaurin 1082:tetracaine 1078:benzocaine 1070:prilocaine 1058:Analgesics 1052:Management 1025:Antivirals 1007:vice versa 975:vice versa 968:Prevention 904:Laboratory 893:urethritis 857:stomatitis 850:gingivitis 807:monogamous 459:Condition 327:antibodies 205:Medication 10605:Sialocele 10588:Parotitis 10329:Open bite 10324:Crossbite 10102:Cherubism 10072:maxillary 9905:Cementoma 9836:Attrition 9652:Impaction 9620:Fluorosis 9529:Anodontia 9524:Ankylosis 9412:Pemphigus 9032:Glossitis 8927:Cleft lip 8905:Cheilitis 8807:Ungrouped 8662:RNA virus 8352:Monkeypox 8132:Cold sore 8056:DNA virus 7989:Proctitis 7874:condyloma 7796:Parasitic 7771:Protozoal 7718:Gonorrhea 7690:Chlamydia 7678:Chancroid 7670:Bacterial 7530:Psoriasis 7438:disorders 7393:Indurated 7294:Urticaria 7246:Localized 7188:epidermal 6971:Varicella 6881:Psoriasis 6792:epidermal 6758:Leiomyoma 6660:Pigmented 6593:Epidermal 6532:eMedicine 5390:: 561–4. 5271:1537-1719 5018:1209-1367 4501:1553-7374 4300:retracted 4292:retracted 4152:0904-2512 4110:cite book 2666:CNS Drugs 2608:1469-493X 2394:0098-7484 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Index

Herpes simplex
Herpesviridae
Herpes (disambiguation)

Oral herpes
/ˈhɜːrpz/
Specialty
Infectious disease
Symptoms
ulcers
lymph nodes
Herpes simplex virus
Risk factors
Decreased immune function
Diagnostic method
PCR
viral culture
Medication
Aciclovir
valaciclovir
paracetamol
viral infection
herpes simplex virus
oral herpes
genital herpes
other forms
blisters
genitalia
ulcers
lymph nodes

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