Knowledge

Cerebral hypoxia

Source đź“ť

52: 552: 170: 843:
If hypoxia results in coma, the length of unconsciousness is often indicative of long-term damage. In some cases coma can give the brain an opportunity to heal and regenerate, but, in general, the longer a coma, the greater the likelihood that the person will remain in a vegetative state until death.
699:
applied within 6 hours of cerebral hypoxia effectively improves survival and neurological outcome. In adults, however, the evidence is less convincing and the first goal of treatment is to restore oxygen to the brain. The method of restoration depends on the cause of the hypoxia. For mild-to-moderate
220:
Cerebral hypoxia refers to oxygen levels in brain tissue, not blood. Blood oxygenation will usually appear normal in cases of hypemic, ischemic, and hystoxic cerebral hypoxia. Even in hypoxic hypoxia blood measures are only an approximate guide; the oxygen level in the brain tissue will depend on
181:
per minute. Initially the body responds to lowered blood oxygen by redirecting blood to the brain and increasing cerebral blood flow. Blood flow may increase up to twice the normal flow but no more. If the increased blood flow is sufficient to supply the brain's oxygen needs then no symptoms will
369:
and places the patient at increased risk for a major stroke in the future. In a broad study in 1998, more than 11 million people were estimated to have experienced a stroke in the United States. Approximately 770,000 of these strokes were symptomatic and 11 million were first-ever silent MRI
622:– Limited oxygen in the environment causes reduced brain function. Divers, aviators, mountain climbers, and fire fighters are all at risk for this kind of cerebral hypoxia. The term also includes oxygen deprivation due to obstructions in the lungs. Choking, strangulation, the crushing of the 229:
Cerebral hypoxia can be caused by any event that severely interferes with the brain's ability to receive or process oxygen. This event may be internal or external to the body. Mild and moderate forms of cerebral hypoxia may be caused by various diseases that interfere with breathing and
820:
of the brain (left side) typically causes problems with speech and language. Damage to the right side of the brain may interfere with the ability to express emotions or interpret what one sees. Damage on either side can cause paralysis of the opposite side of the body.
136:
are termed "anoxia", which can be hypoxic in origin (reduced oxygen availability) or ischemic in origin (oxygen deprivation due to a disruption in blood flow). Brain injury as a result of oxygen deprivation either due to hypoxic or anoxic mechanisms are generally termed
804:
Mild and moderate cerebral hypoxia may result in seizures and impaired memory going forward. The outcome of severe cerebral hypoxia will depend on the success of damage control, amount of brain tissue deprived of oxygen, and the speed with which oxygen was restored.
417:. Sometimes, even an infant that is still in the womb may exhibit signs of HIE or other hypoxic ischemic injury. Fetal distress being one of the most common signs of HIE or other oxygen-depriving event. Other problems during pregnancy may include 847:
Long-term comas can have a significant impact on a patient's family. Families of coma patients often have idealized images of the outcome based on Hollywood movie depictions of coma. Adjusting to the realities of ventilators, feeding tubes,
353:, slurred speech, and mental confusion. The symptoms of a TIA typically resolve within 24 hours, unlike a stroke. Brain injury may still occur in a TIA lasting only a few minutes. Having a TIA is a risk factor for eventually having a stroke. 456:
in the mother. Problems after delivery can include severe prematurity, severe lung or heart disease, serious infections, trauma to the brain or skull, congenital malformations of the brain or very low blood pressure in the baby and due to
185:
However, if blood flow cannot be increased or if doubled blood flow does not correct the problem, symptoms of cerebral hypoxia will begin to appear. Mild symptoms include difficulties with complex learning tasks and reductions in
738:
There has long been a debate over whether newborn infants with cerebral hypoxia should be resuscitated with 100% oxygen or normal air. It has been demonstrated that high concentrations of oxygen lead to generation of oxygen
2191: 153:) is a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation is not total. While HIE is associated in most cases with oxygen deprivation in the neonate due to 217:, but is generally meaningless in other forms of hypoxia. In hypoxic hypoxia 95–100% saturation is considered normal; 91–94% is considered mild and 86–90% moderate. Anything below 86% is considered severe. 700:
cases of hypoxia, removal of the cause of hypoxia may be sufficient. Inhaled oxygen may also be provided. In severe cases treatment may also involve life support and damage control measures.
1285:"Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council" 796:
In severe cases it is extremely important to act quickly. Brain cells are very sensitive to reduced oxygen levels. Once deprived of oxygen they will begin to die off within five minutes.
2738: 365:
which does not have any outward symptoms, and the patient is typically unaware they have had a stroke. Despite its lack of identifiable symptoms, a silent stroke still causes
2111:
Konig P, et al. (1992). "Psychological counseling of the family of patients with craniocerebral injuries (psychological family counseling of severely ill patients)"".
3124: 3119: 3136: 3114: 2287: 1924: 1220: 1725: 1691: 587:(embolic stroke). Focal cerebral ischemia constitutes a large majority of the clinical cases in stroke pathology with the infarct usually occurring in the 1801:
Davis, PG; Tan, A; O'Donnell, CPF; Schulze, A (2004). "Resuscitation of newborn infants with 100% oxygen or air: a systematic review and meta-analysis".
1901: 754:
Brain damage can occur both during and after oxygen deprivation. During oxygen deprivation, cells die due to an increasing acidity in the brain tissue (
785:
levels, and hemodilution (thinning of the blood) coupled with drug-induced hypertension are some treatment techniques currently under investigation.
349:
paralysis (opposite side of body from affected brain hemisphere), or sudden weakness or numbness. A TIA may cause sudden dimming or loss of vision,
2483: 429:, congenital fetal infections, substance/alcohol use, severe fetal anemia, cardiac disease, lung malformations, or problems with blood flow to the 910: 778: 696: 17: 994:
Robinson, LR; Micklesen, PJ; Tirschwell, DL; Lew, HL (Mar 2003). "Predictive value of somatosensory evoked potentials for awakening from coma".
386:. The risk of silent stroke increases with age but may also affect younger adults. Women appear to be at increased risk for silent stroke, with 2478: 808:
If cerebral hypoxia was localized to a specific part of the brain, brain damage will be localized to that region. A general consequence may be
571:– A stroke occurring in a localized area that can either be acute or transient. This may be due to a variety of medical conditions such as an 1144: 329:(AHA/ASA) refined the definition of transient ischemic attack. TIA is now defined as a transient episode of neurologic dysfunction caused by 1612:
Pressman B. D.; Tourje E. J.; Thompson J. R. (Sep 1987). "An early CT sign of ischemic infarction: increased density in a cerebral artery".
751:
and others led to new international guidelines on newborn resuscitation in 2010, recommending the use of normal air instead of 100% oxygen.
2280: 113:. There are four categories of cerebral hypoxia; they are, in order of increasing severity: diffuse cerebral hypoxia (DCH), focal cerebral 1667: 3217: 3790: 3106: 824:
The effects of certain kinds of severe generalized hypoxias may take time to develop. For example, the long-term effects of serious
548:
Cerebral hypoxia is typically grouped into four categories depending on the severity and location of the brain's oxygen deprivation:
190:. If oxygen deprivation continues, cognitive disturbances, and decreased motor control will result. The skin may also appear bluish ( 1140: 3096: 2273: 1852:"Hydrogen peroxide production in leukocytes during cerebral hypoxia and reoxygenation with 100% or 21% oxygen in newborn piglets" 3076: 2749: 3562: 3101: 2733: 1655: 3567: 2939: 2927: 2389: 1493: 703:
A deep coma will interfere with the body's breathing reflexes even after the initial cause of hypoxia has been dealt with;
844:
Even if the patient wakes up, brain damage is likely to be significant enough to prevent a return to normal functioning.
1365:
Leary M. C.; Saver J. L. (2003). "Annual incidence of first silent stroke in the United States: a preliminary estimate".
1248:
Ferro J. M.; et al. (Dec 1996). "Diagnosis of transient ischemic attack by the nonneurologist: A validation study".
636:– Reduced brain function is caused by inadequate oxygen in the blood despite adequate environmental oxygen. Anemia and 213:
Objective measurements of the severity of cerebral hypoxia depend on the cause. Blood oxygen saturation may be used for
3158: 3091: 2646: 1579:
Gardiner M, Eisen S, Murphy C. Training in paediatrics: the essential curriculum. Oxford University Press, Oxford 2009.
533: 527: 255: 1921: 1451:""Silent stroke in patients with transient ischemic attack or minor ischemic stroke". The Dutch TIA Trial Study Group" 1224: 2861: 2664: 1136: 1037:
Geraghty M. C.; Torbey M. T. (2006). "Neuroimaging and serologic markers of neurologic injury after cardiac arrest".
1703: 1326:"Silent stroke in patients with transient ischemic attack or minor ischemic stroke. The Dutch TIA Trial Study Group" 3717: 3334: 1942: 1128: 3349: 3210: 2980: 1744:
Jacobs, Susan E; Berg, Marie; Hunt, Rod; Tarnow-Mordi, William O; Inder, Terrie E; Davis, Peter G (2013-01-31).
762:
build up. When oxygen enters the tissue these materials interact with oxygen to create high levels of oxidants.
462: 3668: 2495: 2471: 2301: 532:
Details of the mechanism of damage from cerebral hypoxia, along with anoxic depolarization, can be found here:
330: 3480: 3174: 3059: 2975: 2917: 2687: 2466: 1979: 1228: 856:
may be difficult. Treatment decisions often involve complex ethical choices and can strain family dynamics.
231: 133: 906:"Hypoxia induces apoptosis via two independent pathways in Jurkat cells: differential regulation by glucose" 3785: 3705: 3410: 3143: 2517: 1715:
This website provides hypoxia related safety tips for aviators working for the United States Navy aviators.
1167: 341:. The symptoms of a TIA can resolve within a few minutes, unlike a stroke. TIAs share the same underlying 3800: 3795: 3522: 3512: 2653: 727:
may all be tried in an effort to get the heart to resume pumping. Severe cerebral hypoxia can also cause
345:
as strokes; a disruption of cerebral blood flow. TIAs and strokes present with the same symptoms such as
326: 251: 3901: 3552: 3527: 3344: 3273: 3203: 3131: 2681: 2353: 1993: 322: 3926: 3869: 3517: 3470: 3320: 3283: 3081: 3049: 3023: 3001: 2850: 2429: 786: 637: 317: 1116: 3991: 3911: 3724: 3678: 3673: 3497: 3475: 3148: 2922: 2336: 2206: 2068:
Wijdicks E. F. M.; Wijdicks C. A. (2006). "The portrayal of coma in contemporary motion pictures".
1410:"Prevalence and risk factors of silent brain infarcts in the population-based Rotterdam Scan Study" 828:
poisoning usually may take several weeks to appear. Recent research suggests this may be due to an
266: 31: 646:( or "stagnant hypoxia") – Reduced brain oxygen is caused by inadequate blood flow to the brain. 3966: 3948: 3430: 3425: 3389: 3359: 3153: 3086: 2842: 2660: 2512: 2502: 2346: 1997: 441: 404: 2265: 3938: 3921: 3916: 3906: 3747: 3683: 3325: 3226: 3018: 3010: 2965: 2641: 2613: 2461: 2138:
Montgomery V, et al. (2002). "The effect of severe traumatic brain injury on the family".
1671: 812:. The long-term effects will depend on the purpose of that portion of the brain. Damage to the 790: 704: 588: 73: 2246: 1157: 3943: 3688: 3547: 3539: 3507: 3394: 3033: 2907: 2725: 2703: 2618: 2541: 2451: 2438: 2363: 1973: 2044: 1207:. Maryland Institute for Emergency Medical Services Systems (2004). Retrieved on 2007-04-13. 658:
may cause stagnant hypoxia. Ischemic hypoxia can also be created by pressure on the brain.
3857: 3852: 3656: 3448: 2970: 2787: 2676: 758:). Additionally, during the period of oxygen deprivation, materials that can easily create 422: 259: 8: 3933: 3700: 2899: 2546: 2401: 2341: 2195: 1847: 748: 663: 606: 601: 338: 309: 301: 118: 565:– A mild to moderate impairment of brain function due to low oxygen levels in the blood. 3847: 3757: 3339: 3069: 3054: 3042: 2792: 2743: 2580: 2443: 2331: 2093: 2081: 1856: 1828: 1778: 1699: 1557: 1540: 1390: 1219: 1019: 1007: 955:"Increased neurogenesis after hypoxic-ischemic encephalopathy in humans is age related" 935: 817: 771: 744: 678: 623: 576: 297: 293: 243: 154: 80: 2200: 1816: 3996: 3638: 3587: 3487: 2832: 2798: 2770: 2761: 2693: 2669: 2536: 2384: 2155: 2151: 2120: 2085: 1954: 1875: 1870: 1851: 1820: 1783: 1765: 1651: 1629: 1562: 1472: 1431: 1382: 1347: 1306: 1265: 1132: 1095: 1054: 1011: 976: 927: 923: 865: 683: 410: 391: 187: 98: 68: 51: 2097: 2019: 1832: 1745: 1394: 1023: 939: 682:– Oxygen is present in brain tissue but cannot be metabolized by the brain tissue. 3643: 3292: 3195: 2955: 2826: 2821: 2606: 2601: 2147: 2077: 1865: 1812: 1773: 1761: 1757: 1677: 1621: 1552: 1462: 1421: 1374: 1337: 1296: 1257: 1085: 1046: 1003: 966: 919: 426: 285: 59: 1916:
Richmond, T. S. (May 1997). "Cerebral Resuscitation after Global Brain Ischemia",
1191: 793:
levels showing a possible reduction in the overall systemic inflammatory process.
613:
Cerebral hypoxia can also be classified by the cause of the reduced brain oxygen:
4001: 3835: 3830: 3742: 3465: 3420: 3300: 2877: 2568: 2211: 1928: 1730: 1301: 1284: 875: 825: 813: 777:
Techniques for preventing damage to brain cells are an area of ongoing research.
767: 732: 618: 272:
Severe cerebral hypoxia and anoxia is usually caused by traumatic events such as
214: 203: 468:
The severity of a neonatal hypoxic-ischaemic brain injury may be assessed using
3884: 3734: 3597: 3557: 3492: 3453: 3364: 2934: 2883: 2711: 2420: 2297: 1074:"Hypoxic-ischemic brain injury: pathophysiology, neuropathology and mechanisms" 880: 853: 849: 659: 651: 605:– A "stroke", caused by complete oxygen deprivation due to an interference in 469: 437: 289: 262: 158: 2260: 1941:
Orozco-Gutierrez A, Rojas-Cerda L, Estrada RM, Gil-Rosales C (December 2010).
1541:"Child abuse by suffocation: A cause of apparent life-threatening events Info" 1261: 1050: 971: 954: 695:
For newborn infants starved of oxygen during birth there is now evidence that
3985: 3752: 3415: 2960: 2912: 2782: 2551: 2507: 2358: 2023: 1940: 1769: 1467: 1450: 1342: 1325: 782: 759: 740: 716: 667: 357: 346: 305: 281: 3579: 448:, excessive bleeding from the placenta, abnormal fetal position such as the 3893: 3805: 3620: 3310: 3253: 2456: 2326: 2309: 2159: 2089: 1998:"Long-Term Effects of Carbon Monoxide Poisoning Are an Autoimmune Reaction" 1958: 1879: 1824: 1787: 1566: 1435: 1386: 1310: 1099: 1058: 1015: 980: 931: 905: 870: 671: 655: 449: 418: 387: 379: 366: 178: 2124: 1633: 1625: 1476: 1426: 1409: 1351: 1269: 1090: 1073: 781:
is the only evidence-supported therapy, but antioxidant drugs, control of
707:
may be required. Additionally, severe cerebral hypoxia causes an elevated
487:
Floppiness, or unreactive to sights or sounds, or more tense and agitated.
3958: 3354: 2415: 2376: 2318: 2241: 2048: 1992: 1599: 1192:"The Maryland Medical Protocols for Emergency Medical Services Providers" 1162: 720: 458: 453: 334: 207: 177:
The brain requires approximately 3.3 ml of oxygen per 100 g of
106: 2183: 1611: 242:
can cause some degree of diffuse cerebral hypoxia. Other causes include
3874: 3864: 3825: 3769: 3762: 3592: 2526: 2396: 1943:"Hyperbaric oxygen in the treatment of asphyxia in two newborn infants" 1803: 1589: 829: 708: 371: 1378: 3628: 3369: 3305: 3261: 3244: 3239: 2636: 2587: 2575: 2558: 2490: 2217: 414: 126: 194:) and heart rate increases. Continued oxygen deprivation results in 3842: 3444: 3381: 3315: 3266: 3111:
Spinal muscular atrophy with lower extremity predominance (SMALED)
2816: 2808: 2774: 2628: 2531: 1670:. Gray Laboratory Cancer Research Trust. 1999-08-01. Archived from 1494:"What You Need To Know About Hypoxic Ischemic Encephalopathy (HIE)" 1202: 885: 809: 763: 755: 728: 724: 580: 572: 430: 342: 277: 269:, and intense exercise at high altitudes prior to acclimatization. 247: 195: 191: 114: 86: 2222: 1517: 2295: 584: 350: 273: 221:
how the body deals with the reduced oxygen content of the blood.
169: 157:, it can occur in all age groups, and is often a complication of 409:
Hypoxic-anoxic events may affect the fetus at various stages of
109:; when the brain is completely deprived of oxygen, it is called 3235: 2855: 2596: 2563: 2067: 837: 833: 647: 627: 445: 375: 362: 239: 235: 122: 102: 993: 789:
is being evaluated with the reduction in total and myocardial
1125:
Basic Neurochemistry: Molecular, Cellular and Medical Aspects
1931:
at the American Association of Critical-Care Nurses website.
1845: 1800: 1746:"Cooling for newborns with hypoxic ischaemic encephalopathy" 731:, which put the patient at risk of self-injury, and various 711:, and in extreme cases the heart may tire and stop pumping. 551: 3611: 630:
exacerbations may also lead to symptoms of hypoxic hypoxia.
383: 199: 1743: 1036: 832:
response caused by carbon monoxide-induced changes in the
121:, and global cerebral ischemia. Prolonged hypoxia induces 712: 477: 473: 1902:
Norwegian paediatrician honoured by University of Athens
499:
Weak breathing, no breathing at all, or rapid breathing.
1221:
National Institute of Neurological Disorders and Stroke
1364: 1111: 1109: 1071: 3225: 2173: 735:
drugs may need to be administered before treatment.
484:
Low Apgar scores, <5 at 5 minutes and 10 minutes.
321:(TIA), is often referred to as a "mini-stroke". The 1106: 2042: 1961:. Archived from the original on September 6, 2013 597:– A complete stoppage of blood flow to the brain. 579:occurring in the affected blood vessels due to a 3983: 2020:"'Rewired brain' revives patient after 19 years" 304:. It is also recreationally self-induced in the 1594:The Gale Encyclopedia of Neurological Disorders 952: 911:American Journal of Physiology. Cell Physiology 779:Hypothermia therapy for neonatal encephalopathy 697:hypothermia therapy for neonatal encephalopathy 436:Problems during labor and delivery can include 472:, which is based on clinical presentation and 3211: 2281: 1407: 1934: 1892:ILCOR Neonatal Resuscitation Guidelines 2010 1648:Animal Models of Acute Neurological Injuries 770:and cause further damage (this is known as " 3000: 1912: 1910: 1726:"Cooling 'cure' averts infant brain damage" 1538: 1448: 1323: 1247: 3791:Chronic cerebrospinal venous insufficiency 3218: 3204: 2288: 2274: 2137: 1150: 609:which affects multiple areas of the brain. 452:, prolonged late stages of labor, or very 50: 1869: 1777: 1556: 1466: 1425: 1341: 1300: 1089: 970: 953:Mattiesen W. R.; et al. (May 2009). 557:one cause of hypoxic anoxic injury (HAI). 480:. Signs and symptoms of HIE may include: 173:CT in a person after generalized hypoxia. 2017: 1907: 1573: 1186: 1184: 903: 575:that causes a hemorrhagic stroke, or an 550: 168: 1750:Cochrane Database of Systematic Reviews 1449:HerderscheĂŞ D, et al. (Sep 1992). 1408:Vermeer S. E.; et al. (Jan 2002). 1324:HerderscheĂŞ D, et al. (Sep 1992). 1215: 1213: 626:all cause this sort of hypoxia. Severe 413:, during labor and delivery and in the 129:, resulting in a hypoxic brain injury. 14: 3984: 3077:Distal hereditary motor neuronopathies 2750:Template:Demyelinating diseases of CNS 1689: 1282: 674:and impede their absorption of oxygen. 502:Need for resuscitation after delivery. 3563:Hereditary hemorrhagic telangiectasia 3199: 2269: 2110: 1520:. Florida Neonatal Neurologic Network 1488: 1486: 1181: 640:are common causes of hypemic hypoxia. 496:Poor muscle tone and absent reflexes. 398: 337:, or retinal ischemia, without acute 164: 3568:Generalized essential telangiectasia 2928:Idiopathic intracranial hypertension 2317: 1846:Kutzsche, S; Ilves, P; Kirkeby, OJ; 1724:Laurance, Jeremy (October 1, 2009). 1210: 1072:Busl K. M.; Greer D. M. (Jan 2010). 904:Malhotra R, et al. (Nov 2001). 1702:Naval Safety Center. Archived from 1646:Jun Chen, Zao C. Xu, Xiao-Ming Xu, 1283:Easton JD, et al. (Jun 2009). 1225:"Cerebral Hypoxia Information Page" 250:-rich environments, ascent from a 198:, long-term loss of consciousness, 24: 3159:Infantile progressive bulbar palsy 2082:10.1212/01.wnl.0000210497.62202.e9 1690:Brooks, Kevin E. (May–June 2005). 1483: 1008:10.1097/01.ccm.0000053643.21751.3b 534:anoxic depolarization in the brain 528:Anoxic depolarization in the brain 378:which are detected via the use of 25: 4013: 2862:Template:Cerebrovascular diseases 2665:Frontotemporal lobar degeneration 2169: 1129:Lippincott Williams & Wilkins 543: 374:. Silent strokes typically cause 3718:Cerebral venous sinus thrombosis 2882:For more detailed coverage, see 2860:For more detailed coverage, see 2831:For more detailed coverage, see 2797:For more detailed coverage, see 2748:For more detailed coverage, see 2152:10.1097/00005373-200206000-00016 2043:Mayo Clinic staff (2006-05-17). 1920:8 (2). Retrieved on 2007-04-13. 1871:10.1203/00006450-200106000-00020 1163:MedlinePlus Medical Encyclopedia 924:10.1152/ajpcell.2001.281.5.c1596 204:cessation of brain stem reflexes 85:Confusion, difficulty speaking, 2131: 2104: 2061: 2036: 2011: 1986: 1895: 1886: 1839: 1794: 1737: 1718: 1683: 1660: 1640: 1605: 1582: 1532: 1510: 1442: 1401: 1358: 1317: 1276: 1241: 1115:Butterworth, Roger F. (1999). " 514:Seizures or abnormal movements. 147:Hypoxic ischemic encephalopathy 18:Hypoxic ischemic encephalopathy 3669:Hepatic veno-occlusive disease 2018:Phillips, Helen (2006-07-03). 1947:Diving and Hyperbaric Medicine 1762:10.1002/14651858.cd003311.pub3 1065: 1030: 987: 946: 897: 555:Aneurysm in a cerebral artery, 105:), specifically involving the 13: 1: 3481:Aneurysm of sinus of Valsalva 3335:Monckeberg's arteriosclerosis 3175:Amyotrophic lateral sclerosis 3060:Hereditary spastic paraplegia 2918:Normal pressure hydrocephalus 1996:Medical Center (2004-09-06). 1817:10.1016/S0140-6736(04)17189-4 1676:Retrieved on 2007-04-13 from 1598:Retrieved on 2007-04-13 from 1229:National Institutes of Health 1127:, 6th edition, Philadelphia: 891: 444:, rupture of the placenta or 3786:Chronic venous insufficiency 3411:Aortoiliac occlusive disease 3144:Progressive muscular atrophy 1596:. The Gale Group, Inc. 2005. 1302:10.1161/STROKEAHA.108.192218 1168:National Library of Medicine 799: 747:after asphyxia. Research by 690: 538: 521: 511:Excessive acid in the blood. 463:MĂĽnchausen syndrome by proxy 27:Oxygen shortage of the brain 7: 3801:Inferior vena cava syndrome 3796:Superior vena cava syndrome 3523:Vertebral artery dissection 3513:Intracranial berry aneurysm 2654:Primary progressive aphasia 1927:September 27, 2007, at the 1692:"Are you a hypoxia expert?" 1650:, Humana Press; 1 edition, 859: 394:being predisposing factors. 327:American Stroke Association 10: 4018: 3902:Hypertensive heart disease 3553:Arteriovenous malformation 3528:Familial aortic dissection 2976:Hashimoto's encephalopathy 2682:Posterior cortical atrophy 2503:Striatonigral degeneration 2354:Cavernous sinus thrombosis 1994:University of Pennsylvania 1147:. Retrieved on 2007-04-13. 766:interfere with the normal 525: 508:Bluish or pale skin color. 402: 323:American Heart Association 29: 3957: 3927:Renovascular hypertension 3892: 3883: 3870:Hepatic artery thrombosis 3818: 3778: 3733: 3637: 3619: 3610: 3578: 3538: 3518:Carotid artery dissection 3471:Abdominal aortic aneurysm 3443: 3403: 3380: 3321:Intermittent claudication 3291: 3284:Peripheral artery disease 3282: 3252: 3234: 3082:Spinal muscular atrophies 3050:Primary lateral sclerosis 3032: 3009: 2993: 2948: 2908:Intracranial hypertension 2898: 2870: 2841: 2807: 2769: 2758: 2724: 2702: 2688:Creutzfeldt–Jakob disease 2627: 2437: 2428: 2414: 2374: 2308: 2232: 2177: 1978:: CS1 maint: unfit URL ( 1262:10.1161/01.STR.27.12.2225 1119:". In: Siegel, George J. 1051:10.1016/j.ncl.2005.10.006 972:10.1007/s00401-009-0509-0 787:Hyperbaric oxygen therapy 638:carbon monoxide poisoning 476:findings, and also using 318:Transient ischemic attack 224: 79: 67: 58: 49: 44: 3912:Hypertensive nephropathy 3725:Post-thrombotic syndrome 3706:Paget–Schroetter disease 3498:Coronary artery aneurysm 3476:Thoracic aortic aneurysm 3149:Progressive bulbar palsy 2940:Intracranial hypotension 2923:Choroid plexus papilloma 2337:Herpesviral encephalitis 1468:10.1161/01.str.23.9.1220 1343:10.1161/01.str.23.9.1220 686:is a well-known example. 595:Global cerebral ischemia 563:Diffuse cerebral hypoxia 3967:Orthostatic hypotension 3949:White coat hypertension 3426:Fibromuscular dysplasia 3390:Carotid artery stenosis 2661:Frontotemporal dementia 2347:Encephalitis lethargica 743:, which have a role in 583:(thrombotic stroke) or 569:Focal cerebral ischemia 405:Neonatal encephalopathy 139:hypoxic/anoxic injuries 3939:Pulmonary hypertension 3922:Secondary hypertension 3917:Essential hypertension 3907:Hypertensive emergency 3748:Portacaval anastomosis 3684:Portal vein thrombosis 3326:Critical limb ischemia 3227:Cardiovascular disease 2966:Hepatic encephalopathy 1117:Hypoxic Encephalopathy 996:Critical Care Medicine 791:creatine phosphokinase 705:mechanical ventilation 589:middle cerebral artery 558: 440:occlusion, torsion or 174: 74:Critical care medicine 63:Arteries beneath brain 3944:Systolic hypertension 3689:Renal vein thrombosis 3548:Arteriovenous fistula 3540:Vascular malformation 3508:Intracranial aneurysm 3395:Renal artery stenosis 3024:Ataxia–telangiectasia 2981:Static encephalopathy 2704:Mitochondrial disease 2542:Spasmodic torticollis 2452:Basal ganglia disease 2045:"Coma: Coping skills" 1626:10.2214/ajr.149.3.583 1545:Paediatr Child Health 1427:10.1161/hs0102.101629 1091:10.3233/NRE-2010-0531 554: 403:Further information: 238:and various sorts of 172: 3858:Paradoxical embolism 3853:Cholesterol embolism 3679:May–Thurner syndrome 3674:Budd–Chiari syndrome 3657:Deep vein thrombosis 3652:primarily lower limb 3431:Raynaud's phenomenon 2971:Toxic encephalopathy 2677:Lewy bodies dementia 1918:AACN Clinical Issues 1539:Bellemare S (2006). 30:For other uses, see 3934:Benign hypertension 3019:Friedreich's ataxia 2402:Meningoencephalitis 2342:Limbic encephalitis 2113:Zentralbl Neurochir 1811:(9442): 1329–1333. 1614:AJR Am J Roentgenol 1078:NeuroRehabilitation 836:sheath surrounding 749:Ola Didrik Saugstad 607:cerebral blood flow 602:Cerebral infarction 493:Low blood pressure. 310:erotic asphyxiation 267:supplemental oxygen 119:cerebral infarction 101:(reduced supply of 3848:Pulmonary embolism 3758:Esophageal varices 3696:upper limb / torso 3340:Arteriolosclerosis 3055:Pseudobulbar palsy 2793:Status epilepticus 2744:Multiple sclerosis 2581:Myoclonic epilepsy 2444:movement disorders 2390:Acute disseminated 2332:Viral encephalitis 2261:Hypoxia experiment 2233:External resources 1857:Pediatric Research 1700:United States Navy 1668:"What is Hypoxia?" 1498:Birth Injury Guide 1158:"Cerebral hypoxia" 918:(5): C1596–C1603. 772:reperfusion injury 745:reperfusion injury 679:Histotoxic hypoxia 670:exert pressure on 559: 454:low blood pressure 399:Pre- and postnatal 298:status asthmaticus 292:, crushing of the 244:status epilepticus 175: 165:Signs and symptoms 134:oxygen deprivation 3979: 3978: 3975: 3974: 3819:Arteries or veins 3814: 3813: 3639:Venous thrombosis 3606: 3605: 3588:Cherry hemangioma 3488:Aortic dissection 3439: 3438: 3274:Buerger's disease 3193: 3192: 3189: 3188: 3185: 3184: 2989: 2988: 2894: 2893: 2833:Template:Headache 2799:Template:Epilepsy 2720: 2719: 2694:Vascular dementia 2537:Status dystonicus 2410: 2409: 2385:Encephalomyelitis 2256: 2255: 2140:Journal of Trauma 1656:978-1-60327-184-4 1379:10.1159/000071128 1256:(12): 2225–2229. 866:Altitude sickness 684:Cyanide poisoning 664:brain hemorrhages 423:maternal diabetes 411:fetal development 392:cigarette smoking 232:blood oxygenation 188:short-term memory 92: 91: 39:Medical condition 16:(Redirected from 4009: 3890: 3889: 3701:Mondor's disease 3644:Thrombophlebitis 3617: 3616: 3293:Arteriosclerosis 3289: 3288: 3250: 3249: 3220: 3213: 3206: 3197: 3196: 3007: 3006: 2998: 2997: 2956:Brain herniation 2767: 2766: 2607:Intention tremor 2602:Essential tremor 2467:Postencephalitic 2435: 2434: 2426: 2425: 2315: 2314: 2296:Diseases of the 2290: 2283: 2276: 2267: 2266: 2175: 2174: 2164: 2163: 2146:(6): 1121–1124. 2135: 2129: 2128: 2108: 2102: 2101: 2076:(9): 1300–1303. 2065: 2059: 2058: 2056: 2055: 2040: 2034: 2033: 2031: 2030: 2015: 2009: 2008: 2006: 2005: 1990: 1984: 1983: 1977: 1969: 1967: 1966: 1938: 1932: 1914: 1905: 1899: 1893: 1890: 1884: 1883: 1873: 1843: 1837: 1836: 1798: 1792: 1791: 1781: 1741: 1735: 1722: 1716: 1714: 1712: 1711: 1687: 1681: 1675: 1664: 1658: 1644: 1638: 1637: 1609: 1603: 1597: 1586: 1580: 1577: 1571: 1570: 1560: 1536: 1530: 1529: 1527: 1525: 1514: 1508: 1507: 1505: 1504: 1490: 1481: 1480: 1470: 1461:(9): 1220–1224. 1446: 1440: 1439: 1429: 1405: 1399: 1398: 1362: 1356: 1355: 1345: 1336:(9): 1220–1224. 1321: 1315: 1314: 1304: 1295:(6): 2276–2293. 1280: 1274: 1273: 1245: 1239: 1238: 1236: 1235: 1217: 1208: 1206: 1198: 1196: 1188: 1179: 1178: 1176: 1175: 1154: 1148: 1141:Freely available 1113: 1104: 1103: 1093: 1069: 1063: 1062: 1034: 1028: 1027: 991: 985: 984: 974: 959:Acta Neuropathol 950: 944: 943: 901: 644:Ischemic hypoxia 517:Problems feeding 427:vascular disease 415:postnatal period 286:smoke inhalation 95:Cerebral hypoxia 60:Circle of Willis 54: 45:Cerebral hypoxia 42: 41: 21: 4017: 4016: 4012: 4011: 4010: 4008: 4007: 4006: 3992:Brain disorders 3982: 3981: 3980: 3971: 3953: 3879: 3836:Microangiopathy 3831:Macroangiopathy 3810: 3774: 3743:Gastric varices 3729: 3642: 3633: 3602: 3574: 3534: 3466:Aortic aneurysm 3452: 3435: 3421:Erythromelalgia 3399: 3376: 3301:Atherosclerosis 3278: 3242: 3230: 3224: 3194: 3181: 3107:Congenital DSMA 3028: 2985: 2944: 2890: 2878:Sleep disorders 2866: 2843:Cerebrovascular 2837: 2803: 2760: 2754: 2716: 2698: 2623: 2569:Choreoathetosis 2442: 2419: 2406: 2370: 2304: 2294: 2257: 2252: 2251: 2228: 2227: 2186: 2172: 2167: 2136: 2132: 2109: 2105: 2066: 2062: 2053: 2051: 2041: 2037: 2028: 2026: 2016: 2012: 2003: 2001: 1991: 1987: 1971: 1970: 1964: 1962: 1939: 1935: 1929:Wayback Machine 1915: 1908: 1900: 1896: 1891: 1887: 1844: 1840: 1799: 1795: 1756:(1): CD003311. 1742: 1738: 1731:The Independent 1723: 1719: 1709: 1707: 1688: 1684: 1666: 1665: 1661: 1645: 1641: 1610: 1606: 1588: 1587: 1583: 1578: 1574: 1537: 1533: 1523: 1521: 1516: 1515: 1511: 1502: 1500: 1492: 1491: 1484: 1447: 1443: 1406: 1402: 1367:Cerebrovasc Dis 1363: 1359: 1322: 1318: 1281: 1277: 1246: 1242: 1233: 1231: 1218: 1211: 1200: 1194: 1190: 1189: 1182: 1173: 1171: 1156: 1155: 1151: 1114: 1107: 1070: 1066: 1035: 1031: 992: 988: 951: 947: 902: 898: 894: 876:Hypothermia cap 862: 826:carbon monoxide 818:Wernicke's area 802: 768:brain chemistry 733:anti-convulsant 693: 634:Hypemic hypoxia 619:Hypoxic hypoxia 556: 546: 541: 530: 524: 490:Low heart rate. 450:breech position 407: 401: 252:deep-water dive 227: 215:hypoxic hypoxia 167: 132:Cases of total 125:cell death via 111:cerebral anoxia 62: 40: 35: 28: 23: 22: 15: 12: 11: 5: 4015: 4005: 4004: 3999: 3994: 3977: 3976: 3973: 3972: 3970: 3969: 3963: 3961: 3955: 3954: 3952: 3951: 3946: 3941: 3936: 3931: 3930: 3929: 3919: 3914: 3909: 3904: 3898: 3896: 3887: 3885:Blood pressure 3881: 3880: 3878: 3877: 3872: 3867: 3862: 3861: 3860: 3855: 3850: 3840: 3839: 3838: 3833: 3822: 3820: 3816: 3815: 3812: 3811: 3809: 3808: 3803: 3798: 3793: 3788: 3782: 3780: 3776: 3775: 3773: 3772: 3767: 3766: 3765: 3760: 3755: 3745: 3739: 3737: 3735:Varicose veins 3731: 3730: 3728: 3727: 3722: 3721: 3720: 3710: 3709: 3708: 3703: 3693: 3692: 3691: 3686: 3681: 3676: 3671: 3661: 3660: 3659: 3648: 3646: 3635: 3634: 3632: 3631: 3625: 3623: 3614: 3608: 3607: 3604: 3603: 3601: 3600: 3598:Spider angioma 3595: 3590: 3584: 3582: 3580:Vascular nevus 3576: 3575: 3573: 3572: 3571: 3570: 3565: 3558:Telangiectasia 3555: 3550: 3544: 3542: 3536: 3535: 3533: 3532: 3531: 3530: 3525: 3520: 3515: 3510: 3500: 3495: 3493:Aortic rupture 3490: 3485: 3484: 3483: 3478: 3473: 3458: 3456: 3454:pseudoaneurysm 3441: 3440: 3437: 3436: 3434: 3433: 3428: 3423: 3418: 3413: 3407: 3405: 3401: 3400: 3398: 3397: 3392: 3386: 3384: 3378: 3377: 3375: 3374: 3373: 3372: 3367: 3365:Oxycholesterol 3362: 3357: 3352: 3347: 3337: 3331: 3330: 3329: 3328: 3323: 3318: 3313: 3308: 3297: 3295: 3286: 3280: 3279: 3277: 3276: 3271: 3270: 3269: 3258: 3256: 3247: 3232: 3231: 3223: 3222: 3215: 3208: 3200: 3191: 3190: 3187: 3186: 3183: 3182: 3180: 3179: 3178: 3177: 3166: 3165: 3164: 3163: 3162: 3161: 3156: 3146: 3141: 3140: 3139: 3134: 3129: 3128: 3127: 3122: 3117: 3109: 3104: 3099: 3094: 3089: 3079: 3065: 3064: 3063: 3062: 3057: 3052: 3038: 3036: 3030: 3029: 3027: 3026: 3021: 3015: 3013: 3004: 2995: 2991: 2990: 2987: 2986: 2984: 2983: 2978: 2973: 2968: 2963: 2958: 2952: 2950: 2946: 2945: 2943: 2942: 2937: 2935:Cerebral edema 2932: 2931: 2930: 2925: 2920: 2915: 2904: 2902: 2896: 2895: 2892: 2891: 2889: 2888: 2887: 2886: 2884:Template:Sleep 2874: 2872: 2868: 2867: 2865: 2864: 2858: 2853: 2847: 2845: 2839: 2838: 2836: 2835: 2829: 2824: 2819: 2813: 2811: 2805: 2804: 2802: 2801: 2795: 2790: 2785: 2779: 2777: 2764: 2756: 2755: 2753: 2752: 2746: 2741: 2736: 2730: 2728: 2722: 2721: 2718: 2717: 2715: 2714: 2712:Leigh syndrome 2708: 2706: 2700: 2699: 2697: 2696: 2685: 2684: 2679: 2674: 2673: 2672: 2658: 2657: 2656: 2651: 2650: 2649: 2633: 2631: 2625: 2624: 2622: 2621: 2616: 2611: 2610: 2609: 2604: 2593: 2592: 2591: 2590: 2585: 2584: 2583: 2573: 2572: 2571: 2561: 2556: 2555: 2554: 2549: 2544: 2539: 2523: 2522: 2521: 2520: 2515: 2510: 2505: 2500: 2499: 2498: 2488: 2487: 2486: 2476: 2475: 2474: 2469: 2464: 2448: 2446: 2439:Extrapyramidal 2432: 2423: 2421:encephalopathy 2412: 2411: 2408: 2407: 2405: 2404: 2399: 2394: 2393: 2392: 2381: 2379: 2372: 2371: 2369: 2368: 2367: 2366: 2356: 2351: 2350: 2349: 2344: 2339: 2334: 2323: 2321: 2312: 2306: 2305: 2298:nervous system 2293: 2292: 2285: 2278: 2270: 2264: 2263: 2254: 2253: 2250: 2249: 2237: 2236: 2234: 2230: 2229: 2226: 2225: 2214: 2203: 2187: 2182: 2181: 2179: 2178:Classification 2171: 2170:External links 2168: 2166: 2165: 2130: 2103: 2060: 2035: 2010: 2000:. ScienceDaily 1985: 1953:(4): 218–220. 1933: 1922:Free full text 1906: 1894: 1885: 1864:(6): 834–842. 1838: 1793: 1736: 1717: 1682: 1674:on 2003-09-21. 1659: 1639: 1604: 1581: 1572: 1551:(8): 493–495. 1531: 1509: 1482: 1441: 1400: 1373:(3): 280–285. 1357: 1316: 1275: 1240: 1223:(2018-03-08). 1209: 1180: 1149: 1145:NCBI Bookshelf 1105: 1064: 1045:(1): 107–121. 1029: 1002:(3): 960–967. 986: 965:(5): 525–534. 945: 895: 893: 890: 889: 888: 883: 881:Space exposure 878: 873: 868: 861: 858: 854:muscle wasting 801: 798: 692: 689: 688: 687: 675: 660:Cerebral edema 652:cardiac arrest 641: 631: 611: 610: 598: 592: 566: 545: 544:Classification 542: 540: 537: 526:Main article: 523: 520: 519: 518: 515: 512: 509: 506: 503: 500: 497: 494: 491: 488: 485: 470:Sarnat staging 438:umbilical cord 400: 397: 396: 395: 354: 290:drug overdoses 256:high altitudes 226: 223: 166: 163: 159:cardiac arrest 155:birth asphyxia 90: 89: 83: 77: 76: 71: 65: 64: 56: 55: 47: 46: 38: 26: 9: 6: 4: 3: 2: 4014: 4003: 4000: 3998: 3995: 3993: 3990: 3989: 3987: 3968: 3965: 3964: 3962: 3960: 3956: 3950: 3947: 3945: 3942: 3940: 3937: 3935: 3932: 3928: 3925: 3924: 3923: 3920: 3918: 3915: 3913: 3910: 3908: 3905: 3903: 3900: 3899: 3897: 3895: 3891: 3888: 3886: 3882: 3876: 3873: 3871: 3868: 3866: 3863: 3859: 3856: 3854: 3851: 3849: 3846: 3845: 3844: 3841: 3837: 3834: 3832: 3829: 3828: 3827: 3824: 3823: 3821: 3817: 3807: 3804: 3802: 3799: 3797: 3794: 3792: 3789: 3787: 3784: 3783: 3781: 3777: 3771: 3768: 3764: 3761: 3759: 3756: 3754: 3753:Caput medusae 3751: 3750: 3749: 3746: 3744: 3741: 3740: 3738: 3736: 3732: 3726: 3723: 3719: 3716: 3715: 3714: 3711: 3707: 3704: 3702: 3699: 3698: 3697: 3694: 3690: 3687: 3685: 3682: 3680: 3677: 3675: 3672: 3670: 3667: 3666: 3665: 3662: 3658: 3655: 3654: 3653: 3650: 3649: 3647: 3645: 3640: 3636: 3630: 3627: 3626: 3624: 3622: 3618: 3615: 3613: 3609: 3599: 3596: 3594: 3591: 3589: 3586: 3585: 3583: 3581: 3577: 3569: 3566: 3564: 3561: 3560: 3559: 3556: 3554: 3551: 3549: 3546: 3545: 3543: 3541: 3537: 3529: 3526: 3524: 3521: 3519: 3516: 3514: 3511: 3509: 3506: 3505: 3504: 3501: 3499: 3496: 3494: 3491: 3489: 3486: 3482: 3479: 3477: 3474: 3472: 3469: 3468: 3467: 3463: 3460: 3459: 3457: 3455: 3450: 3446: 3442: 3432: 3429: 3427: 3424: 3422: 3419: 3417: 3416:Degos disease 3414: 3412: 3409: 3408: 3406: 3402: 3396: 3393: 3391: 3388: 3387: 3385: 3383: 3379: 3371: 3368: 3366: 3363: 3361: 3358: 3356: 3353: 3351: 3348: 3346: 3343: 3342: 3341: 3338: 3336: 3333: 3332: 3327: 3324: 3322: 3319: 3317: 3314: 3312: 3309: 3307: 3304: 3303: 3302: 3299: 3298: 3296: 3294: 3290: 3287: 3285: 3281: 3275: 3272: 3268: 3265: 3264: 3263: 3260: 3259: 3257: 3255: 3251: 3248: 3246: 3241: 3237: 3233: 3228: 3221: 3216: 3214: 3209: 3207: 3202: 3201: 3198: 3176: 3173: 3172: 3171: 3168: 3167: 3160: 3157: 3155: 3152: 3151: 3150: 3147: 3145: 3142: 3138: 3135: 3133: 3130: 3126: 3123: 3121: 3118: 3116: 3113: 3112: 3110: 3108: 3105: 3103: 3100: 3098: 3095: 3093: 3090: 3088: 3085: 3084: 3083: 3080: 3078: 3075: 3074: 3073: 3071: 3067: 3066: 3061: 3058: 3056: 3053: 3051: 3048: 3047: 3046: 3044: 3040: 3039: 3037: 3035: 3031: 3025: 3022: 3020: 3017: 3016: 3014: 3012: 3008: 3005: 3003: 2999: 2996: 2992: 2982: 2979: 2977: 2974: 2972: 2969: 2967: 2964: 2962: 2961:Reye syndrome 2959: 2957: 2954: 2953: 2951: 2947: 2941: 2938: 2936: 2933: 2929: 2926: 2924: 2921: 2919: 2916: 2914: 2913:Hydrocephalus 2911: 2910: 2909: 2906: 2905: 2903: 2901: 2897: 2885: 2881: 2880: 2879: 2876: 2875: 2873: 2869: 2863: 2859: 2857: 2854: 2852: 2849: 2848: 2846: 2844: 2840: 2834: 2830: 2828: 2825: 2823: 2820: 2818: 2815: 2814: 2812: 2810: 2806: 2800: 2796: 2794: 2791: 2789: 2786: 2784: 2781: 2780: 2778: 2776: 2772: 2768: 2765: 2763: 2757: 2751: 2747: 2745: 2742: 2740: 2737: 2735: 2732: 2731: 2729: 2727: 2726:Demyelinating 2723: 2713: 2710: 2709: 2707: 2705: 2701: 2695: 2692: 2691: 2690: 2689: 2683: 2680: 2678: 2675: 2671: 2668: 2667: 2666: 2662: 2659: 2655: 2652: 2648: 2645: 2644: 2643: 2640: 2639: 2638: 2635: 2634: 2632: 2630: 2626: 2620: 2617: 2615: 2614:Restless legs 2612: 2608: 2605: 2603: 2600: 2599: 2598: 2595: 2594: 2589: 2586: 2582: 2579: 2578: 2577: 2574: 2570: 2567: 2566: 2565: 2562: 2560: 2557: 2553: 2552:Blepharospasm 2550: 2548: 2545: 2543: 2540: 2538: 2535: 2534: 2533: 2530: 2529: 2528: 2525: 2524: 2519: 2516: 2514: 2511: 2509: 2508:Hemiballismus 2506: 2504: 2501: 2497: 2494: 2493: 2492: 2489: 2485: 2482: 2481: 2480: 2477: 2473: 2470: 2468: 2465: 2463: 2460: 2459: 2458: 2455: 2454: 2453: 2450: 2449: 2447: 2445: 2440: 2436: 2433: 2431: 2427: 2424: 2422: 2417: 2413: 2403: 2400: 2398: 2395: 2391: 2388: 2387: 2386: 2383: 2382: 2380: 2378: 2373: 2365: 2362: 2361: 2360: 2359:Brain abscess 2357: 2355: 2352: 2348: 2345: 2343: 2340: 2338: 2335: 2333: 2330: 2329: 2328: 2325: 2324: 2322: 2320: 2316: 2313: 2311: 2307: 2303: 2299: 2291: 2286: 2284: 2279: 2277: 2272: 2271: 2268: 2262: 2259: 2258: 2248: 2244: 2243: 2239: 2238: 2235: 2231: 2224: 2220: 2219: 2215: 2213: 2209: 2208: 2204: 2202: 2198: 2197: 2193: 2189: 2188: 2185: 2180: 2176: 2161: 2157: 2153: 2149: 2145: 2141: 2134: 2126: 2122: 2118: 2114: 2107: 2099: 2095: 2091: 2087: 2083: 2079: 2075: 2071: 2064: 2050: 2046: 2039: 2025: 2024:New Scientist 2021: 2014: 1999: 1995: 1989: 1981: 1975: 1960: 1956: 1952: 1948: 1944: 1937: 1930: 1926: 1923: 1919: 1913: 1911: 1903: 1898: 1889: 1881: 1877: 1872: 1867: 1863: 1859: 1858: 1853: 1849: 1842: 1834: 1830: 1826: 1822: 1818: 1814: 1810: 1806: 1805: 1797: 1789: 1785: 1780: 1775: 1771: 1767: 1763: 1759: 1755: 1751: 1747: 1740: 1733: 1732: 1727: 1721: 1706:on 2007-02-08 1705: 1701: 1697: 1693: 1686: 1679: 1673: 1669: 1663: 1657: 1653: 1649: 1643: 1635: 1631: 1627: 1623: 1620:(3): 583–56. 1619: 1615: 1608: 1601: 1595: 1591: 1585: 1576: 1568: 1564: 1559: 1554: 1550: 1546: 1542: 1535: 1519: 1518:"Parent Info" 1513: 1499: 1495: 1489: 1487: 1478: 1474: 1469: 1464: 1460: 1456: 1452: 1445: 1437: 1433: 1428: 1423: 1419: 1415: 1411: 1404: 1396: 1392: 1388: 1384: 1380: 1376: 1372: 1368: 1361: 1353: 1349: 1344: 1339: 1335: 1331: 1327: 1320: 1312: 1308: 1303: 1298: 1294: 1290: 1286: 1279: 1271: 1267: 1263: 1259: 1255: 1251: 1244: 1230: 1226: 1222: 1216: 1214: 1204: 1193: 1187: 1185: 1169: 1165: 1164: 1159: 1153: 1146: 1142: 1138: 1137:0-397-51820-X 1134: 1130: 1126: 1122: 1118: 1112: 1110: 1101: 1097: 1092: 1087: 1083: 1079: 1075: 1068: 1060: 1056: 1052: 1048: 1044: 1040: 1033: 1025: 1021: 1017: 1013: 1009: 1005: 1001: 997: 990: 982: 978: 973: 968: 964: 960: 956: 949: 941: 937: 933: 929: 925: 921: 917: 913: 912: 907: 900: 896: 887: 884: 882: 879: 877: 874: 872: 869: 867: 864: 863: 857: 855: 851: 845: 841: 839: 835: 831: 827: 822: 819: 815: 811: 806: 797: 794: 792: 788: 784: 783:blood glucose 780: 775: 773: 769: 765: 761: 760:free radicals 757: 752: 750: 746: 742: 741:free radicals 736: 734: 730: 726: 722: 718: 717:defibrilation 714: 710: 706: 701: 698: 685: 681: 680: 676: 673: 669: 668:hydrocephalus 665: 661: 657: 653: 649: 645: 642: 639: 635: 632: 629: 625: 621: 620: 616: 615: 614: 608: 604: 603: 599: 596: 593: 590: 586: 582: 578: 574: 570: 567: 564: 561: 560: 553: 549: 536: 535: 529: 516: 513: 510: 507: 504: 501: 498: 495: 492: 489: 486: 483: 482: 481: 479: 475: 471: 466: 464: 460: 455: 451: 447: 443: 439: 434: 432: 428: 424: 420: 416: 412: 406: 393: 389: 385: 381: 377: 373: 368: 364: 360: 359: 358:Silent stroke 355: 352: 348: 347:contralateral 344: 340: 336: 332: 328: 324: 320: 319: 315: 314: 313: 311: 307: 306:fainting game 303: 299: 295: 291: 287: 283: 282:strangulation 279: 275: 270: 268: 264: 261: 260:unpressurized 257: 253: 249: 245: 241: 237: 233: 222: 218: 216: 211: 209: 205: 201: 197: 193: 189: 183: 180: 171: 162: 160: 156: 152: 148: 144: 140: 135: 130: 128: 124: 120: 116: 112: 108: 104: 100: 97:is a form of 96: 88: 84: 82: 78: 75: 72: 70: 66: 61: 57: 53: 48: 43: 37: 33: 19: 3894:Hypertension 3806:Venous ulcer 3712: 3695: 3663: 3651: 3621:Inflammation 3502: 3461: 3350:Hyperplastic 3311:Fatty streak 3254:Inflammation 3169: 3068: 3041: 3002:Degenerative 2739:Inflammatory 2686: 2619:Stiff-person 2457:Parkinsonism 2430:Degenerative 2327:Encephalitis 2310:Inflammation 2300:, primarily 2240: 2216: 2205: 2190: 2143: 2139: 2133: 2119:(2): 78–84. 2116: 2112: 2106: 2073: 2069: 2063: 2052:. Retrieved 2038: 2027:. Retrieved 2013: 2002:. Retrieved 1988: 1974:cite journal 1963:. Retrieved 1950: 1946: 1936: 1917: 1897: 1888: 1861: 1855: 1848:Saugstad, OD 1841: 1808: 1802: 1796: 1753: 1749: 1739: 1729: 1720: 1708:. Retrieved 1704:the original 1695: 1685: 1672:the original 1662: 1647: 1642: 1617: 1613: 1607: 1593: 1584: 1575: 1548: 1544: 1534: 1522:. Retrieved 1512: 1501:. Retrieved 1497: 1458: 1454: 1444: 1420:(1): 21–25. 1417: 1413: 1403: 1370: 1366: 1360: 1333: 1329: 1319: 1292: 1288: 1278: 1253: 1249: 1243: 1232:. Retrieved 1172:. Retrieved 1170:. 2007-04-05 1161: 1152: 1124: 1120: 1081: 1077: 1067: 1042: 1038: 1032: 999: 995: 989: 962: 958: 948: 915: 909: 899: 871:Choking game 846: 842: 823: 814:Broca's area 807: 803: 795: 776: 753: 737: 702: 694: 677: 672:brain tissue 656:heart attack 643: 633: 617: 612: 600: 594: 568: 562: 547: 531: 467: 461:in cases of 435: 419:preeclampsia 408: 390:and current 388:hypertension 380:neuroimaging 370:infarcts or 367:brain damage 356: 316: 271: 254:, flying at 228: 219: 212: 202:, seizures, 184: 179:brain tissue 176: 150: 146: 142: 138: 131: 110: 94: 93: 36: 3959:Hypotension 3503:head / neck 3355:Cholesterol 3245:capillaries 3154:Fazio–Londe 2994:Both/either 2788:Generalised 2647:Early-onset 2642:Alzheimer's 2377:spinal cord 2242:MedlinePlus 2049:Mayo Clinic 1904:, Norway.gr 1678:Archive.org 1600:Answers.com 1201:(1.00  1084:(1): 5–13. 1039:Neurol Clin 721:epinephrine 459:suffocation 372:hemorrhages 335:spinal cord 331:focal brain 208:brain death 3986:Categories 3875:Vasculitis 3865:Thrombosis 3826:Angiopathy 3770:Varicocele 3763:Hemorrhoid 3593:Halo nevus 3449:dissection 3240:arterioles 2762:paroxysmal 2734:Autoimmune 2527:Dyskinesia 2397:Meningitis 2375:Brain and 2054:2007-04-13 2029:2007-04-13 2004:2007-04-13 1965:2013-06-06 1804:The Lancet 1710:2007-04-13 1524:28 January 1503:2021-10-05 1234:2007-04-13 1174:2007-04-13 892:References 830:autoimmune 709:heart rate 339:infarction 246:, work in 3629:Phlebitis 3370:Trans fat 3306:Foam cell 3262:Arteritis 3229:(vessels) 2759:Episodic/ 2637:Tauopathy 2588:Akathisia 2576:Myoclonus 2559:Athetosis 2491:Tauopathy 2223:389088001 2218:SNOMED CT 2070:Neurology 1770:1465-1858 1590:"Hypoxia" 800:Prognosis 691:Treatment 650:, shock, 577:occlusion 539:Diagnosis 522:Mechanism 505:Weak cry. 234:. Severe 127:apoptosis 69:Specialty 3997:Ischemia 3843:Embolism 3445:Aneurysm 3382:Stenosis 3316:Atheroma 3267:Aortitis 3236:Arteries 3125:SMALED2B 3120:SMALED2A 2817:Migraine 2809:Headache 2775:epilepsy 2771:Seizures 2629:Dementia 2532:Dystonia 2160:12045640 2098:43411074 2090:16682658 1959:23111939 1925:Archived 1880:11385146 1850:(2001). 1833:24825982 1825:15474135 1788:23440789 1696:Approach 1567:19030315 1436:11779883 1395:33095581 1387:12865617 1311:19423857 1100:20130351 1059:16443133 1024:18080596 1016:12627012 981:19277687 940:10558756 932:11600423 886:Ulegyria 860:See also 850:bedsores 816:and the 810:epilepsy 764:Oxidants 756:acidosis 729:seizures 725:atropine 624:windpipe 581:thrombus 573:aneurysm 442:prolapse 431:placenta 382:such as 343:etiology 278:drowning 265:without 248:nitrogen 196:fainting 192:cyanosis 182:result. 123:neuronal 115:ischemia 87:seizures 81:Symptoms 3664:abdomen 3345:Hyaline 3137:SMA-PME 3132:SMA-PCH 3115:SMALED1 2827:Tension 2822:Cluster 2547:Meige's 2364:Amoebic 2212:D002534 2125:1636327 1779:7003568 1634:3497548 1558:2528639 1477:1519274 1352:1519274 1270:8969785 1227:. U.S. 1166:. U.S. 1123:(eds.) 838:neurons 585:embolus 376:lesions 351:aphasia 308:and in 294:trachea 274:choking 99:hypoxia 32:Hypoxia 4002:Oxygen 2856:Stroke 2670:Pick's 2597:Tremor 2564:Chorea 2247:001435 2158:  2123:  2096:  2088:  1957:  1878:  1831:  1823:  1786:  1776:  1768:  1654:  1632:  1565:  1555:  1475:  1455:Stroke 1434:  1414:Stroke 1393:  1385:  1350:  1330:Stroke 1309:  1289:Stroke 1268:  1250:Stroke 1199:  1135:  1121:et al. 1098:  1057:  1022:  1014:  979:  938:  930:  852:, and 834:myelin 723:, and 648:Stroke 628:asthma 591:(MCA). 446:uterus 363:stroke 300:, and 258:in an 240:anemia 236:asthma 225:Causes 206:, and 103:oxygen 3779:Other 3612:Veins 3462:torso 3404:Other 3170:both: 3102:DSMA1 3097:SMAX2 3092:SMAX1 3072:only: 3045:only: 2949:Other 2871:Other 2783:Focal 2416:Brain 2319:Brain 2201:437.9 2094:S2CID 1829:S2CID 1391:S2CID 1195:(PDF) 1020:S2CID 936:S2CID 425:with 361:is a 302:shock 263:cabin 107:brain 3713:head 3243:and 2773:and 2484:PKAN 2479:NBIA 2207:MeSH 2196:9-CM 2156:PMID 2121:PMID 2086:PMID 1980:link 1955:PMID 1876:PMID 1821:PMID 1784:PMID 1766:ISSN 1754:2013 1652:ISBN 1630:PMID 1563:PMID 1526:2012 1473:PMID 1432:PMID 1383:PMID 1348:PMID 1307:PMID 1266:PMID 1133:ISBN 1096:PMID 1055:PMID 1012:PMID 977:PMID 928:PMID 774:"). 666:and 654:and 384:fMRI 325:and 200:coma 3360:LDL 3087:SMA 3070:LMN 3043:UMN 3034:MND 2900:CSF 2851:TIA 2496:PSP 2472:NMS 2441:and 2302:CNS 2192:ICD 2148:doi 2078:doi 1866:doi 1813:doi 1809:364 1774:PMC 1758:doi 1622:doi 1618:149 1553:PMC 1463:doi 1422:doi 1375:doi 1338:doi 1297:doi 1258:doi 1203:MiB 1143:at 1086:doi 1047:doi 1004:doi 967:doi 963:117 920:doi 916:281 713:CPR 478:MRI 474:EEG 151:HIE 145:). 143:HAI 3988:: 3464:: 3447:/ 3238:, 3011:SA 2518:OA 2513:HD 2462:PD 2245:: 2221:: 2210:: 2199:: 2154:. 2144:52 2142:. 2117:53 2115:. 2092:. 2084:. 2074:66 2072:. 2047:. 2022:. 1976:}} 1972:{{ 1951:40 1949:. 1945:. 1909:^ 1874:. 1862:49 1860:. 1854:. 1827:. 1819:. 1807:. 1782:. 1772:. 1764:. 1752:. 1748:. 1728:, 1698:. 1694:. 1628:. 1616:. 1592:. 1561:. 1549:11 1547:. 1543:. 1496:. 1485:^ 1471:. 1459:23 1457:. 1453:. 1430:. 1418:33 1416:. 1412:. 1389:. 1381:. 1371:16 1369:. 1346:. 1334:23 1332:. 1328:. 1305:. 1293:40 1291:. 1287:. 1264:. 1254:27 1252:. 1212:^ 1183:^ 1160:. 1139:. 1131:. 1108:^ 1094:. 1082:26 1080:. 1076:. 1053:. 1043:24 1041:. 1018:. 1010:. 1000:31 998:. 975:. 961:. 957:. 934:. 926:. 914:. 908:. 840:. 719:, 715:, 662:, 465:. 433:. 421:, 333:, 312:. 296:, 288:, 284:, 280:, 276:, 210:. 161:. 117:, 3641:/ 3451:/ 3219:e 3212:t 3205:v 2663:/ 2418:/ 2289:e 2282:t 2275:v 2194:- 2184:D 2162:. 2150:: 2127:. 2100:. 2080:: 2057:. 2032:. 2007:. 1982:) 1968:. 1882:. 1868:: 1835:. 1815:: 1790:. 1760:: 1734:. 1713:. 1680:. 1636:. 1624:: 1602:. 1569:. 1528:. 1506:. 1479:. 1465:: 1438:. 1424:: 1397:. 1377:: 1354:. 1340:: 1313:. 1299:: 1272:. 1260:: 1237:. 1205:) 1197:. 1177:. 1102:. 1088:: 1061:. 1049:: 1026:. 1006:: 983:. 969:: 942:. 922:: 149:( 141:( 34:. 20:)

Index

Hypoxic ischemic encephalopathy
Hypoxia

Circle of Willis
Specialty
Critical care medicine
Symptoms
seizures
hypoxia
oxygen
brain
ischemia
cerebral infarction
neuronal
apoptosis
oxygen deprivation
birth asphyxia
cardiac arrest

brain tissue
short-term memory
cyanosis
fainting
coma
cessation of brain stem reflexes
brain death
hypoxic hypoxia
blood oxygenation
asthma
anemia

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

↑