Knowledge

Intraocular lens

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A prescription is formulated for the patient and customization of the IOL's refractive power is done by exposing either the centre or the periphery of the lens to a metered dose of UV light, with the help of a contact lens on the cornea. This exposed part will swell slightly, adjusting the lens surface curvature. Meridional exposure can be done in much the same way to correct for astigmatism. Several exposures can be made for fine tuning, spaced over several days. Once the lens has been optimised a final exposure of the whole lens is made to lock the changes, after which the lens will no longer be adjustable and can be used outdoors.
311:. Manifest refraction is the familiar test where the eye doctor rotates lenses in front of the eye, asking the patient, "Which is better (or clearer), this one or this one?" Corneal topography is considered a more quantitative test, and for purposes of aligning a toric IOL, most surgeons use a measurement called simulated keratometry (SimK), which is calculated by the internal programming of the corneal topography machine, to determine the astigmatic meridian on the surface of the cornea. The astigmatic meridian can also be identified using corneal wavefront technology or paraxial curvature matching. 395: 217:(CLE). During CLEAR, the crystalline lens is extracted and an IOL replaces it in a process that is very similar to cataract surgery: both involve lens replacement, local anesthesia, last approximately 30 minutes, and require making a small incision in the eye for lens insertion. People recover from CLEAR surgery 1–7 days after the operation. During this time, they should avoid strenuous exercise or anything else that significantly raises blood pressure. They should visit their ophthalmologists regularly for several weeks to monitor the IOL implants. 31: 742: 470:, in which one eye is made emmetropic and the other myopic, can partially compensate for the loss of accommodation and enable clear vision at multiple distances. More versatile types of lenses (multifocal and accommodating IOLs) were introduced in 2003 in the United States, with the approval by the Food and Drug Administration. These come at an additional cost to the recipient beyond what Medicare will pay and each has advantages and disadvantages. 498:
taken while a patient still has cataracts, and they cannot account for minuscule shifts that occur during healing. An adjustable IOL allows surgeons to implant it and then, once healing is complete, use an ultraviolet light delivery device to fine tune it until it suits the patient. An early example being the (RxSight) Light Adjustable Lens (LAL).
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images of the multifocal lens which cause the halo effect. When matched correctly to the eye, these lenses are intended to have little effect on distance vision, and improve middle distance and near vision. In practice they have been satisfactory for intermediate distances, but not good enough for near vision.
539:, using hinges at both ends to "latch on" and move forward and backward inside the eye using the same nerves and musculature as normal accommodation. These IOLs have a 4.5-mm square-edged optic and a long hinged plate design with polyimide loops at the end of the haptics. The hinges are made of an advanced 801:
The appropriate refractive power of the IOL is selected, much like a spectacle lens prescription, to provide the desired refractive outcome. Pre-operative measurements, including corneal curvature, axial length, and white-to-white measurements are used to estimate the required power of the IOL. These
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Toric IOLs must be of the correct power and aligned inside the eye on a meridian that counteracts the preexisting astigmatism. One of the causes of unsatisfactory refractory correction is that the lens may be incorrectly placed by the surgeon, or rotate inside the eye if is too short, which may occur
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procedure (LASIK), a form of eye surgery that does not work for people with serious vision problems. Effective IOL implants also eliminate the need for glasses or contact lenses post-surgery for most patients. Cataracts will not appear or return, as the lens has been removed. The disadvantage is that
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Standard toric IOLs are monofocal, permanently focused on distant objects. Multifocal toric IOLs are also available. These lenses provide the patient not only with correction of preexisting astigmatism, but also with vision that can focus at far and short distances, including short reading distance.
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The eyes and lenses must not be exposed to random ultraviolet light before and during the adjustment process, and protective glasses must be worn from the operation until the lens is locked. When the eye has healed, which is usually 2 to 4 weeks after IOL implantation, refraction adjustment is done.
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An adjustable IOL is unlike any other lens as its prescription power can be adjusted after surgery once all healing is complete. All other IOLs require surgeons to use pre-surgery measurements to determine a patient's post-surgery lens power. The drawback of this is that pre-surgery measurements are
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IOL implantation carries several risks associated with eye surgeries, such as infection, loosening of the lens, lens rotation, inflammation, nighttime halos and retinal detachment. Though IOLs enable many patients to have reduced dependence on glasses, most patients still rely on glasses for certain
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has two hinged struts on opposite edges which displace the lens along the optical axis when an inward transverse force is applied to the haptic loops at the outer ends of the struts (the components transferring the movement of the contact points to the device), and it springs back when the force is
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People who have a multifocal IOL after their cataract is removed may be less likely to need additional glasses compared with people who have standard monofocal lenses. However, people receiving multifocal lenses may experience more visual problems than with monofocal lenses. The most common adverse
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Extended depth-of-focus (EDOF) is an intraocular lens technology for treating presbyopia. Where multifocal IOLs have two or more focal points, EDOF lenses form a single elongated focal point to enhance depth of focus. The intention is to reduce glare, halos, and other photic phenomena which occur
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Phakic IOLs (PIOLs) are intraocular lenses which are placed in an eye that still contains a natural human crystalline lens. PIOLs are sometimes referred to as an 'implantable contact lenses' (ICLs). As with other IOLs, PIOLs can be either spheric or toric. Toric PIOLs have to be aligned with the
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The principle on which they work is to form a single, axially elongated focal point, unlike monofocal lenses which have a single focal point, and multifocal lenses which have two or more stacked discrete focal points. The elongated zone of focus is intended to prevent the overlapped out-of-focus
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Multifocal IOLs attempt to provide simultaneous viewing of distance vision and near vision. Trifocal IOLs can provide intermediate vision in addition. Many multifocal IOL designs attempt to achieve this simultaneous viewing focus using a concentric ring design, which alternates distance and near
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A Cochrane Review found little evidence of important differences between blue‐light filtering and non‐blue‐light filtering lenses for protecting the macula (back of the eye) after cataract surgery. This may have been due to studies being too small and too short‐term to provide reliable results.
664:, placed in the posterior chamber in front of the natural crystalline lens. This type of PIOLs is gaining more and more popularity. They have special vaulting so as not to be in contact with the normal lens. The main complication with older versions was a small possibility of cataract formation. 166:
As of 2021, nearly 28 million cataract procedures take place annually worldwide, a large proportion in India. That is about 75,000 procedures per day globally. The procedure can be done under local or topical anesthesia with the patient awake throughout the operation. The use of a flexible IOL
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Severe myopia or hyperopia with coexisting presbyopia are the primary indicators for refractive lens exchange (RLE), as RLE leads to complete loss of accommodation. Underlying regular astigmatism can also be managed by RLE, even beyond the scope of corneal incisional techniques, by toric lens
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Many aphakic and pseudophakic IOLs such as anterior chamber IOLs or 3 piece posterior chamber IOLs can be used interchangeably. The exception are one piece IOLs, which must be placed within the capsular bag at the time of cataract surgery and hence cannot be used as secondary implants.
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implants. Marginal indications for RLE are presbyopia without ametropia, using a multifocal lens implant, presbyopia with underlying astigmatism, and prepresbyopoa hyperopia of from +5 to +10 D not amenable to keratorefractive surgery or phakic IOL due to a shallow anterior chamber.
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with multifocal IOLs. A possible drawback is decrease in image quality due to aberrations. EDOF IOLs have often been combined with multifocus designs, which has caused some confusion. It has been suggested that lenses combining more than one optical design be termed "hybrid IOLs".
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is the absence of the natural crystalline lens. The aphakic state is usually due to surgery to remove a cataractous lens, but post-surgical aphakia is rare nowadays because of the ubiquity of intraocular lenses. Rarely, aphakia can be post-traumatic or congenital in nature.
591:, toric IOLs have different powers in different meridians of the lens, and they must be positioned on the correct meridian to reverse the preexisting astigmatism. If the toric IOL is not on the correct meridian, it may need to be repositioned in a second procedure. 220:
CLEAR has a 90% success rate (risks include wound leakage, infection, inflammation, and astigmatism). CLEAR can be performed only on patients ages 40 and older. This is to ensure that eye growth, which disrupts IOL lenses, will not occur post-surgery.
171:, and the recovery period is about 2–3 weeks. After surgery, patients should avoid strenuous exercise or anything else that significantly increases blood pressure. They should visit their ophthalmologists regularly for 3 weeks to monitor the implants. 334:
Complications of RLE are similar to those after cataract surgery, but with the difference that RLE is often used in very short or very long eyes and patients’ ages tend to be significantly lower, so consideration must be given to longer term effects.
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Blue light filtering IOLs filter the UV and high-energy blue light present in natural and artificial light, both of which can cause vision problems; however, too much filtering of blue light can increase depression, especially in the winter months
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and acrylic polymers, both of which are soft foldable inert materials. This allows the lens to be folded and inserted into the eye through a smaller incision. Specifically, acrylic lenses are a better choice in people who have a history of
656:, attached by claws to the mid-peripheral iris by a technique called enclavation. It is believed to have a lesser effect on corneal endothelium. The main complication with this type is their tendency to cause endothelial cell reduction. 793:. A study found that in participants with a history of uveitis, eyes treated with hydrophobic acrylic IOLs were over twice as likely to have a best corrected visual acuity of 20/40 or more, compared to eyes treated with silicone IOLs. 681:). The trademarked "Natural Yellow" material is available in three hydrophilic IOLs. Dr. Patrick H. Benz of Benz Research and Development created the first IOL material to incorporate the same UV-A blocking and violet light filtering 445:
Monofocal IOLs are standard lenses used in cataract surgery. One of the major disadvantages of these conventional IOLs is that they can only be focused for one particular distance – either optical infinity (rendering the eye
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enables the lens to be rolled for insertion into the capsular bag through a very small incision, thus avoiding the need for stitches. This procedure usually takes less than 30 minutes in the hands of an experienced
520:). However, many accommodating IOLs used today only achieve a very limited improvements in near vision which reduced over time. Accommodative intraocular lenses may also have a slightly higher risk of developing 162:
that provides multiple-focused vision at far and reading distance, and adaptive IOLs that provide limited visual accommodation. Multifocal IOLs can also be trifocal IOLs or extended depth of focus (EDOF) lenses.
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When standard IOLs are implanted with a CLEAR procedure, in substitution of the patient's crystalline, astigmatism is typically not corrected, as astigmatism is mainly attributable to a deformation of the
462:(change focus from near to far, far to near, and to distances in between). This is not a concern for most cataract surgeries, as they are primarily performed on elderly people that are already completely 878:
As of 2021, approximately four million cataract procedures take place annually in the U.S. and nearly 28 million worldwide, a large proportion in India. That is about 75,000 procedures per day globally.
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IOLs usually consist of a small plastic lens with plastic side struts, called haptics, to hold the lens in place in the capsular bag inside the eye. IOLs were originally made of a rigid material (
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of 6/7.5 (20/25) when targeted for distance) in 55% of cases and within one dioptre (correlates to 6/12 (20/40) when targeted for distance) in 85% of cases. Developments in intra-operative
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Belluci R. An Introduction to Intraocular Lenses: Material, Optics, Haptics, Design and Aberration. In: Güell JL (ed): Cataract. ESASO Course Series. Basel, Karger, 2013, vol 3, pp 38–55
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The intraocular lens did not find widespread acceptance in cataract surgery until the 1970s, when further developments in lens design and surgical techniques had come about.
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and thus may be candidates for a toric IOL. Cataract surgery with implantation of a toric IOL is essentially the same as cataract surgery with a conventional IOL. Like toric
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GĂźell JL, Morral M, Kook D, Kohnen T (November 2010). "Phakic intraocular lenses part 1: historical overview, current models, selection criteria, and surgical techniques".
1093: 648:, placed in the anterior chamber. They are notorious for their negative impact on the corneal endothelial lining, which is vital for maintaining a healthy clear cornea. 2323: 524:(PCO), though there is some uncertainty around this finding. PCO is a common side-effect of many cataract surgeries and is easily treatable with a one-time laser 621:
have been used to produce the elongated focal zone. In effect, accurate focus at any distance is compromised to achieve less noticeable blur at all distances.
428:). A less-common type of intraocular lens, which is sometimes used if a PCIOL is not an option for a patient or if the situation requires a phakic IOL (PIOL). 377:
is the substitution of the natural crystalline lens with an IOL, as is often done after cataract extraction or less often to correct major refractive error.
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methods include several formulae, including Hagis, Hoffer Q, Holladay 1, Holladay 2, and SRK/T. Free online calculators use similar input data. A history of
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Sanders D, Vukich JA (December 2006). "Comparison of implantable collamer lens (ICL) and laser-assisted in situ keratomileusis (LASIK) for low myopia".
2253: 1499: 360:) refers to an intraocular lens implanted without removal of the original crystalline lens, and this is performed solely to correct refractive error. 265:
0.03–0.05% eye infection risk, which in worst case can lead to blindness. (This risk exists in all eye surgery procedures and is not unique to IOLs.)
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that's present in the human crystalline lens in order to attempt to protect the retina after cataract extraction of the natural crystalline lens.
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AliĂł JL, Chipont E, BenEzra D, Fakhry MA (December 2002). "Comparative performance of intraocular lenses in eyes with cataract and uveitis".
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have demonstrated power calculations that provide improved outcomes, yielding 80% of patients within 0.5 dioptres (7/7.5 (20/25) or better).
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visual effects from multifocal IOLs include glare, halos (rings around lights), and a loss of contrast sensitivity in low-light conditions.
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activities, such as reading. These reading glasses may be avoided in some cases if multifocal IOLs, trifocal IOLs or EDOF lenses are used.
418:). This is by far the most common type of implanted lens after cataract surgery, as this is the natural and optimum position for a lens. 806:
requires different calculations to take this into account. Refractive results using power calculation formulae based on pre-operative
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intraocular lenses may form PCOs a few months after implantation. They are easily treatable, and typically only require a one-time
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the eye's ability to change focus (accommodate) has generally been reduced or eliminated, depending on the kind of lens implanted.
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focal points. However, concentric ring multifocal lenses are prone to glare and mildly compromised focus at all ranges of vision.
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Jain, Sneha; Patel, Alpa S.; Tripathy, Koushik; DelMonte, Derek W; Baartman, Brandon (3 October 2022). DelMonte, Derek W (ed.).
1085: 826: 1883:"Combination of Toric and multifocal intraocular lens implantation in bilateral cataract patients with unilateral astigmatism" 1690: 636:
meridian of astigmatism; toric IOL misalignment or rotation can lead to residual or even greater astigmatism postoperatively.
158:. Most IOLs fitted today are fixed monofocal lenses matched to distance vision. However, other types are available, such as a 1991: 437:
Pseudophakic IOLs are lenses implanted during cataract surgery, immediately after removal of the patient's crystalline lens.
555:, where the contractions of the ciliary body which would focus the eye with the natural lens are used to focus the implant. 1720: 402: 2315: 292:
has a slightly oval shape. If misaligned, preexisting astigmatism may not be corrected completely or may even increase.
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The surgeon can ascertain the astigmatic, or steepest, meridian in a number of ways, including manifest refraction or
1474: 1434: 1755: 644: 2485: 1366:"Excimer laser refractive surgery versus phakic intraocular lenses for the correction of moderate to high myopia" 838: 715: 139:
lens (or false lens). Both kinds of IOLs are designed to provide the same light-focusing function as the natural
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refers to a lens implanted during cataract surgery, immediately after removal of the patient's crystalline lens.
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Some newer lens designs attempt to allow the eye to regain some ability to change focus from distance to near (
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In 2006, a centrally perforated ICL (i.e., the Hole-ICL) was created to improve aqueous humour circulation.
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Some of the risks that were found in the early 2000s during a three-year study of the Artisan lenses were:
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Vicchrilli, Sue; Glasser, David B.; McNett, Cherie; Burke, Mara Pearse; Repka, Michael X. (October 2018).
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An accommodating lens made by Eyeonics, now Bausch & Lomb, was approved by the US FDA in 2003. The
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reaction, and deduced that the transparent material was inert and useful for implantation in the eye.
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called BioSil that was thoroughly tested to make sure it was capable of unlimited flexing in the eye.
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A posterior capsular opacity (PCO) around a posterior chamber IOL (as seen on retroillumination in a
576: 151: 718:(PCO), often referred to as "after cataract", is the most common complication of cataract surgery. 53: 2285:"SRK/T Formula: A Review: A combination of linear regression method with a theoretical eye model" 1829: 1119: 698: 630: 371:
refers to a lens implanted secondarily in an eye already aphakic from previous surgery or trauma.
351: 196: 130: 2657: 1159:"Clinical Outcomes after Binocular Implantation of a New Trifocal Diffractive Intraocular Lens" 853: 842: 831: 1616: 394: 320: 214: 782: 639:
Depending on their attachment site to the eye, PIOLs can be divided into three categories:
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Downie LE, Busija L, Keller PR, et al. (Cochrane Eyes and Vision Group) (May 2018).
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Before surgery (natural crystalline lens, left). After surgery (implanted PCIOL, right).
2616: 2591: 2412: 2395: 2371: 2346: 2218: 2193: 2174: 2082: 2057: 2038: 1959: 1934: 1907: 1882: 1810: 1597: 1549: 1522: 1466: 1457:. In Spaeth, George L.; Danesh-Meyer, Helen V.; Goldberg, Ivan; Kampik, Anselm (eds.). 1426: 1346: 1288: 1231: 1206: 1183: 1158: 1063: 1020: 786: 454:). Patients who undergo a standard IOL implantation no longer experience clouding from 308: 244: 154:), although this has largely been superseded by the use of flexible materials, such as 126: 2162: 1798: 224:
Once implanted, IOLs have three major benefits. First, they are an alternative to the
2621: 2417: 2376: 2223: 2166: 2122: 2087: 2030: 2025: 1987: 1964: 1912: 1802: 1671: 1601: 1589: 1554: 1470: 1430: 1395: 1338: 1330: 1292: 1280: 1236: 1127: 1055: 1012: 274: 192: 41: 2042: 1350: 1276: 1067: 1024: 199:(PIOL), as it is implanted without removing the patient's natural crystalline lens. 2611: 2603: 2407: 2366: 2358: 2213: 2209: 2205: 2178: 2158: 2114: 2077: 2073: 2069: 2020: 1954: 1946: 1902: 1894: 1814: 1794: 1698: 1661: 1657: 1653: 1581: 1544: 1534: 1462: 1422: 1385: 1381: 1377: 1322: 1272: 1226: 1222: 1218: 1178: 1170: 1047: 1004: 912: 846: 749:
The materials that have been used to manufacture intraocular lens implants include
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was the first to successfully implant an intraocular lens on 29 November 1949, at
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Wormstone IM, Wang L, Liu CS (February 2009). "Posterior capsule opacification".
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Kohnen, Thomas; Kook, Daniel; Morral, Merce; GĂźell, Jose Luis (1 December 2010).
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Kretz FT, Breyer D, Diakonis VF, Klabe K, Henke F, Auffarth GU, Kaymak H (2017).
1051: 857: 552: 168: 59: 1945:(3). Philadelphia, Pa.: Lippincott Williams & Wilkins Open Access: 194–202. 2118: 1783:"Toric intraocular lenses: correcting astigmatism while controlling axis shift" 1326: 1008: 532: 343:
Implants can be used with or without removal of the natural crystalline lens:
2058:"Blue-light filtering intraocular lenses (IOLs) for protecting macular health" 1933:
Kanclerz, Piotr; Toto, Francesca; Grzybowski, Andrzej; Alio, Jorge L. (2020).
1174: 2636: 1334: 906: 811: 803: 765:. PMMA was the first material to be used successfully in intraocular lenses. 741: 183:
Intraocular lenses have been used since 1999 for correcting larger errors in
106: 30: 2436:"Alcon Official Site: Developing Innovative Eye Care Treatments | Alcon.com" 2008: 2000: 1898: 1572:
Dick HB, Gerste RD (November 2021). "Future Intraocular Lens Technologies".
856:(PMMA) made by ICI (Imperial Chemical Industries). Ridley had observed that 2647: 2625: 2421: 2380: 2227: 2170: 2126: 2091: 2034: 1968: 1916: 1675: 1593: 1558: 1399: 1342: 1284: 1240: 1131: 1059: 1016: 900: 869: 865: 834:– site of first permanent insertion of an intraocular lens, 8 February 1950 730: 588: 2362: 1806: 1721:"New Device Approval – CrystaLens Model AT-45 Accommodating IOL – P030002" 1492:"Premium IOLs—A Legal and Ethical Guide to Billing Medicare Beneficiaries" 1207:"Multifocal versus monofocal intraocular lenses after cataract extraction" 726: 682: 584: 525: 140: 2254:"Achieving Better Outcomes Using Free Online Post-LASIK IOL Calculators" 1539: 147:, but LASIK is not an alternative to an IOL for treatment of cataracts. 2194:"Types of intraocular lenses for cataract surgery in eyes with uveitis" 861: 807: 778: 564: 467: 463: 447: 2536: 1118:
Moshirfar, Majid; Milner, Dallin; Patel, Bhupendra C. (21 June 2022).
921: â€“ Intraocular lens system to compensate for macular degeneration 909: â€“ Tearing an opening in the lens capsule during cataract surgery 1205:
de Silva SR, Evans JR, Kirthi V, Ziaei M, Leyland M (December 2016).
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with replacement by silicone oil, such as persons with proliferative
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rotation of the lens inside the eye one or two days after surgery.
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involving PMMA windshield material did not show any rejection or
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Shimizu, K; Kamiya, K; Igarashi, A; Shiratani, T (March 2012).
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may be used during the CLEAR procedure to correct astigmatism.
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Xia, Tina; Martinez, Christine E.; Tsai, Linda M. (May 2020).
2006: 1756:"Crystalens: The First Accommodating Intraocular Lens Implant" 1311:"Phakic intraocular lenses: Part 2: Results and complications" 129:. If the natural lens is left in the eye, the IOL is known as 580: 225: 203: 144: 1489: 1254: 1252: 1250: 2316:"Intraoperative Wavefront Aberrometry: Wave of the Future?" 777:
or are likely to have to undergo retinal surgery requiring
314: 1932: 1261:"Extended depth-of-focus technology in intraocular lenses" 810:
leave people within 0.5 dioptres of target (correlates to
2435: 1614: 1247: 2148: 1406: 1204: 1156: 891: â€“ Eyeglasses with manually adjustable focal length 1935:"Extended Depth-of-Field Intraocular Lenses: An Update" 1520: 1448: 1446: 1259:
Kohnen, Thomas; Suryakumar, Rajaraman (February 2020).
2592:"Update on Intraocular Lens Formulas and Calculations" 1928: 1926: 16:
Lens implanted in the eye to treat cataracts or myopia
1830:"IOL Implants: Lens Replacement and Cataract Surgery" 1308: 1200: 1198: 1196: 1194: 994: 768:
Advances in technology have brought about the use of
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Intraocular lens manufacturers | Eyekon Medical, Inc
1860:"Astigmatism and Cataract? A Toric IOL Can Fix Both" 1461:(Fourth ed.). W.B. Saunders. pp. 187–191. 1443: 1117: 521: 288:
if the eye was incorrectly measured, or because the
1923: 1781:Shimizu, K; Misawa, A; Suzuki, Y (September 1994). 1780: 1304: 1302: 583:procedure. About 40% of Americans have significant 350:is the presence of the natural crystalline lenses. 206:(LASIK) in those with significant nearsightedness. 2247: 2245: 2243: 2241: 2239: 2237: 2055: 1880: 1191: 692: 254:(other studies have shown a risk of 0.5–1.0%), and 1632: 1630: 1126:. National Center for Biotechnology Information. 2634: 2406:(1). Missouri State Medical Association: 58–62. 2191: 2104: 1691:"Accommodating IOLs: Design, Technique, Results" 1413:Poothullil, Antony M.; Azar, Dimitri T. (2007). 1299: 1258: 1079: 1077: 796: 450:) or a fixed finite distance (rendering the eye 117:or for correcting other vision problems such as 2589: 2234: 1521:Carson D, Hill WE, Hong X, Karakelle M (2014). 849:company of Brighton, East Sussex, England from 1713: 1627: 1412: 915: â€“ Removal of opacified lens from the eye 1762:. University of Rochester Flaum Eye Institute 1636: 1074: 1037: 845:at London. That lens was manufactured by the 2098: 1874: 1787:Journal of Cataract & Refractive Surgery 1565: 1315:Journal of Cataract & Refractive Surgery 1265:Journal of Cataract & Refractive Surgery 1113: 1111: 1086:"Future of cataract surgery seems promising" 671: 2198:The Cochrane Database of Systematic Reviews 2192:Leung TG, Lindsley K, Kuo IC (March 2014). 2062:The Cochrane Database of Systematic Reviews 1981: 1646:The Cochrane Database of Systematic Reviews 1459:Ophthalmic Surgery: Principles and Practice 1370:The Cochrane Database of Systematic Reviews 1363: 1211:The Cochrane Database of Systematic Reviews 1031: 988: 2387: 2307: 2251: 2151:Journal of Cataract and Refractive Surgery 1881:Liang JL, Tian F, Zhang H, Teng H (2016). 1853: 1851: 1849: 1847: 1682: 1608: 1571: 1452: 1084:Lindstrom, Richard L. (10 February 2021). 997:Journal of Cataract and Refractive Surgery 903: â€“ Lenses placed on the eye's surface 603: 29: 2615: 2411: 2370: 2217: 2081: 2024: 1958: 1906: 1665: 1548: 1538: 1421:(Second ed.). Mosby. pp. 1–18. 1389: 1357: 1230: 1182: 1108: 1083: 933: â€“ Complication of cataract surgery, 2344: 1152: 1150: 1148: 825: 740: 702: 401: 393: 315:Indications for refractive lens exchange 202:Phakic IOL appear to be lower risk than 88: 1857: 1844: 1637:Ong HS, Evans JR, Allan BD (May 2014). 575:. Astigmatism can also be treated with 2635: 1975: 1887:International Journal of Ophthalmology 1747: 1514: 897: â€“ Absence of the lens of the eye 551:reduced. It is implanted in the eye's 389: 209:More commonly, IOLs are implanted via 195:eyes. This type of IOL is also called 35:A posterior chamber IOL (with haptics) 2596:Asia-Pacific Journal of Ophthalmology 2393: 2326:from the original on 26 February 2023 2322:. American Academy of Ophthalmology. 2313: 2295:from the original on 11 February 2023 2276: 2264:from the original on 11 February 2023 2185: 1939:Asia-Pacific Journal of Ophthalmology 1688: 1617:"Light Adjustable Intraocular lenses" 1502:from the original on 21 February 2023 1453:Kook, Daniel; Kohnen, Thomas (2012). 1145: 1096:from the original on 16 February 2023 699:Cataract surgery § Complications 211:Clear Lens Extraction And Replacement 2351:The British Journal of Ophthalmology 2142: 1827: 1821: 1623:. American Academy of Ophthalmology. 722: 432: 143:lens. This can be an alternative to 2396:"The Evolution of Cataract Surgery" 2394:Davis, G. (January–February 2016). 1832:. American Academy of Ophthalmology 721:In a small percentage of patients, 594: 113:usually as part of a treatment for 13: 2583: 2282: 2252:Goldsberry, Dennis H. (May 2012). 1753: 1467:10.1016/B978-1-4377-2250-5.00031-X 1427:10.1016/B978-0-323-03599-6.50063-8 927: â€“ Method of cataract surgery 492: 338: 280:remaining near or far sightedness, 14: 2674: 937: 931:Uveitis–glaucoma–hyphema syndrome 531:Accommodating IOLs interact with 2026:10.1136/bjophthalmol-2011-300148 1986:(3rd ed.). Mosby Elsevier. 1364:Barsam A, Allan BD (June 2014). 505: 329: 2554: 2529: 2503: 2478: 2453: 2428: 2338: 2314:Roach, Linda (September 2013). 2133: 2049: 1483: 1455:"31 - Refractive lens exchange" 1277:10.1097/j.jcrs.0000000000000109 716:Posterior capsule opacification 693:Posterior capsule opacification 522:posterior capsule opacification 406:An anterior chamber IOL (ACIOL) 178: 2345:Williams HP (September 2001). 2210:10.1002/14651858.CD007284.pub2 2074:10.1002/14651858.CD011977.pub2 1658:10.1002/14651858.CD009667.pub2 1382:10.1002/14651858.CD007679.pub4 1223:10.1002/14651858.CD003169.pub4 624: 257:0.4% risk of corneal swelling. 1: 2163:10.1016/s0886-3350(02)01452-9 1799:10.1016/S0886-3350(13)80232-5 1417:. In Azar, Dimitri T. (ed.). 981: 797:Selection of refractive power 473: 236:a yearly loss of 1.8% of the 2608:10.1097/APO.0000000000000293 2515:Johnson & Johnson Vision 2347:"Sir Harold Ridley's vision" 1951:10.1097/APO.0000000000000296 1858:Heiting G (September 2016). 1729:Food and Drug Administration 1689:Slade, Stephen (July 2005). 1586:10.1016/j.ophtha.2020.12.025 1052:10.1097/ICO.0b013e31802cbf3c 789:, such as persons with high 736: 567:used to correct preexisting 440: 7: 1982:Yanoff M, Duker JS (2009). 1828:Boyd K (16 November 2016). 889:Adjustable-focus eyeglasses 882: 785:or who are at high risk of 761:, hydrophilic acrylate and 571:astigmatism at the time of 512:Multifocal intraocular lens 480:Multifocal intraocular lens 160:multifocal intraocular lens 10: 2679: 2119:10.1016/j.exer.2008.10.016 1327:10.1016/j.jcrs.2010.10.007 1009:10.1016/j.jcrs.2010.08.014 821: 745:Acrylic MICS-IOL in holder 696: 628: 509: 477: 318: 301: 2107:Experimental Eye Research 1175:10.1002/14651858.CD012648 751:poly(methyl methacrylate) 672:Blue-light filtering IOLs 577:limbal relaxing incisions 563:A toric IOL is a type of 458:, but they are unable to 76: 66: 52: 40: 28: 23: 2562:"Home EN - Morcher GmbH" 1163:Journal of Ophthalmology 558: 1899:10.18240/ijo.2016.12.11 1695:Review of Ophthalmology 631:Phakic intraocular lens 604:Extended depth-of-focus 528:procedure (see below). 197:phakic intraocular lens 1760:www.urmc.rochester.edu 1527:Clinical Ophthalmology 854:polymethylmethacrylate 835: 746: 712: 661:Sulcus-supported PIOLs 407: 399: 94: 2511:"IOLs & Implants" 2363:10.1136/bjo.85.9.1022 960:Johnson & Johnson 860:pilots who sustained 829: 744: 706: 645:Angle-supported PIOLs 412:Posterior chamber IOL 405: 397: 321:Clear lens extraction 261:Other risks include: 215:clear lens extraction 204:excimer laser surgery 92: 2541:Rayner : Global 2486:"Intraocular Lenses" 1862:. AllAboutVision.com 1124:www.ncbi.nlm.nih.gov 1090:occular surgery news 816:wavefront technology 783:diabetic retinopathy 615:Spherical aberration 422:Anterior chamber IOL 135:, otherwise it is a 2653:Implants (medicine) 1735:on 29 December 2008 1540:10.2147/OPTH.S66760 925:Phacoemulsification 843:St Thomas' Hospital 832:St Thomas' Hospital 729:procedure (using a 390:Location of implant 2461:"Intraocular Lens" 2289:crstodayeurope.com 2258:crstodayeurope.com 1701:on 17 October 2006 1419:Refractive Surgery 1120:"Cataract Surgery" 836: 787:retinal detachment 747: 713: 653:Iris-fixated PIOLs 408: 400: 309:corneal topography 245:retinal detachment 127:refractive surgery 95: 2643:Corrective lenses 2490:www.bausch.com.my 1993:978-0-323-04332-8 1893:(12): 1766–1771. 1580:(11): e206–e213. 977: 970: 963: 956: 953:Bausch & Lomb 839:Sir Harold Ridley 723:posterior chamber 433:Pseudophakic IOLs 238:endothelial cells 119:short sightedness 109:implanted in the 87: 86: 68:OPS-301 code 2670: 2629: 2619: 2577: 2576: 2574: 2572: 2558: 2552: 2551: 2549: 2547: 2533: 2527: 2526: 2524: 2522: 2517:. 24 August 2022 2507: 2501: 2500: 2498: 2496: 2482: 2476: 2475: 2473: 2471: 2457: 2451: 2450: 2448: 2446: 2432: 2426: 2425: 2415: 2391: 2385: 2384: 2374: 2342: 2336: 2335: 2333: 2331: 2311: 2305: 2304: 2302: 2300: 2280: 2274: 2273: 2271: 2269: 2249: 2232: 2231: 2221: 2189: 2183: 2182: 2157:(12): 2096–108. 2146: 2140: 2137: 2131: 2130: 2102: 2096: 2095: 2085: 2053: 2047: 2046: 2028: 2004: 1998: 1997: 1979: 1973: 1972: 1962: 1930: 1921: 1920: 1910: 1878: 1872: 1871: 1869: 1867: 1855: 1842: 1841: 1839: 1837: 1825: 1819: 1818: 1778: 1772: 1771: 1769: 1767: 1751: 1745: 1744: 1742: 1740: 1731:. Archived from 1717: 1711: 1710: 1708: 1706: 1697:. 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CRSTEurope. 2233: 2184: 2141: 2132: 2097: 2048: 2019:(3): 409–412. 1999: 1992: 1974: 1922: 1873: 1843: 1820: 1793:(5): 523–526. 1773: 1746: 1712: 1681: 1626: 1607: 1564: 1513: 1482: 1475: 1442: 1435: 1405: 1356: 1298: 1271:(2): 298–304. 1246: 1190: 1144: 1107: 1073: 1030: 986: 985: 983: 980: 979: 978: 939: 938:Makers of IOLs 936: 935: 934: 928: 922: 916: 910: 904: 898: 892: 884: 881: 823: 820: 798: 795: 757:, hydrophobic 738: 735: 733:) to clarify. 694: 691: 673: 670: 666: 665: 657: 649: 629:Main article: 626: 623: 619:pinhole effect 605: 602: 596: 593: 589:contact lenses 560: 557: 510:Main article: 507: 504: 494: 491: 478:Main article: 475: 472: 442: 439: 434: 431: 430: 429: 419: 391: 388: 383: 382: 372: 361: 340: 337: 331: 328: 319:Main article: 316: 313: 285: 284: 281: 278: 272: 266: 259: 258: 255: 248: 241: 180: 177: 85: 84: 77: 74: 73: 70: 64: 63: 56: 50: 49: 44: 38: 37: 34: 26: 25: 15: 9: 6: 4: 3: 2: 2675: 2664: 2661: 2659: 2658:Ophthalmology 2656: 2654: 2651: 2649: 2646: 2644: 2641: 2640: 2638: 2627: 2623: 2618: 2613: 2609: 2605: 2601: 2597: 2593: 2588: 2587: 2567: 2563: 2557: 2542: 2538: 2537:"Rayner IOLs" 2532: 2516: 2512: 2506: 2491: 2487: 2481: 2466: 2462: 2456: 2441: 2440:www.alcon.com 2437: 2431: 2423: 2419: 2414: 2409: 2405: 2401: 2397: 2390: 2382: 2378: 2373: 2368: 2364: 2360: 2356: 2352: 2348: 2341: 2325: 2321: 2317: 2310: 2294: 2290: 2286: 2279: 2263: 2259: 2255: 2248: 2246: 2244: 2242: 2240: 2238: 2229: 2225: 2220: 2215: 2211: 2207: 2203: 2199: 2195: 2188: 2180: 2176: 2172: 2168: 2164: 2160: 2156: 2152: 2145: 2136: 2128: 2124: 2120: 2116: 2113:(2): 257–69. 2112: 2108: 2101: 2093: 2089: 2084: 2079: 2075: 2071: 2067: 2063: 2059: 2052: 2044: 2040: 2036: 2032: 2027: 2022: 2018: 2014: 2010: 2003: 1995: 1989: 1985: 1984:Ophthalmology 1978: 1970: 1966: 1961: 1956: 1952: 1948: 1944: 1940: 1936: 1929: 1927: 1918: 1914: 1909: 1904: 1900: 1896: 1892: 1888: 1884: 1877: 1861: 1854: 1852: 1850: 1848: 1831: 1824: 1816: 1812: 1808: 1804: 1800: 1796: 1792: 1788: 1784: 1777: 1761: 1757: 1750: 1734: 1730: 1726: 1722: 1716: 1700: 1696: 1692: 1685: 1677: 1673: 1668: 1663: 1659: 1655: 1651: 1647: 1640: 1633: 1631: 1622: 1618: 1611: 1603: 1599: 1595: 1591: 1587: 1583: 1579: 1575: 1574:Ophthalmology 1568: 1560: 1556: 1551: 1546: 1541: 1536: 1533:: 2105–2113. 1532: 1528: 1524: 1517: 1501: 1497: 1493: 1486: 1478: 1476:9781437722505 1472: 1468: 1464: 1460: 1456: 1449: 1447: 1438: 1436:9780323035996 1432: 1428: 1424: 1420: 1416: 1409: 1401: 1397: 1392: 1387: 1383: 1379: 1375: 1371: 1367: 1360: 1352: 1348: 1344: 1340: 1336: 1332: 1328: 1324: 1320: 1316: 1312: 1305: 1303: 1294: 1290: 1286: 1282: 1278: 1274: 1270: 1266: 1262: 1255: 1253: 1251: 1242: 1238: 1233: 1228: 1224: 1220: 1216: 1212: 1208: 1201: 1199: 1197: 1195: 1185: 1180: 1176: 1172: 1169:(5): 962891. 1168: 1164: 1160: 1153: 1151: 1149: 1133: 1129: 1125: 1121: 1114: 1112: 1095: 1091: 1087: 1080: 1078: 1069: 1065: 1061: 1057: 1053: 1049: 1045: 1041: 1034: 1026: 1022: 1018: 1014: 1010: 1006: 1002: 998: 991: 987: 975: 968: 961: 954: 950: 946: 942: 941: 932: 929: 926: 923: 920: 917: 914: 911: 908: 907:Capsulorhexis 905: 902: 899: 896: 893: 890: 887: 886: 880: 876: 873: 871: 867: 863: 859: 855: 852: 848: 844: 840: 833: 828: 819: 817: 813: 812:visual acuity 809: 805: 804:LASIK surgery 794: 792: 788: 784: 780: 776: 771: 766: 764: 760: 756: 752: 743: 734: 732: 728: 724: 719: 717: 710: 705: 700: 690: 686: 684: 680: 669: 663: 662: 658: 655: 654: 650: 647: 646: 642: 641: 640: 637: 632: 622: 620: 616: 610: 601: 592: 590: 586: 582: 581:excimer laser 578: 574: 570: 566: 556: 554: 549: 544: 542: 538: 534: 529: 527: 523: 519: 518:accommodation 513: 506:Accommodating 503: 499: 490: 486: 481: 471: 469: 465: 461: 457: 453: 449: 438: 427: 423: 420: 417: 413: 410: 409: 404: 396: 387: 380: 376: 373: 370: 365: 362: 359: 355: 354: 349: 346: 345: 344: 336: 330:Complications 327: 322: 312: 310: 305: 303: 299: 293: 291: 282: 279: 276: 273: 270: 267: 264: 263: 262: 256: 253: 250:0.6% risk of 249: 246: 243:0.6% risk of 242: 239: 235: 234: 233: 230: 227: 226:excimer laser 222: 218: 216: 212: 207: 205: 200: 198: 194: 190: 186: 176: 172: 170: 164: 161: 157: 153: 148: 146: 142: 138: 134: 133: 128: 124: 120: 116: 112: 108: 104: 100: 91: 81: 75: 71: 69: 65: 61: 57: 55: 51: 48: 45: 43: 39: 32: 27: 22: 19: 2599: 2595: 2569:. 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Retrieved 1089: 1043: 1039: 1033: 1000: 996: 990: 973: 966: 959: 952: 948: 944: 901:Contact lens 877: 874: 870:foreign body 866:World War II 862:eye injuries 837: 800: 767: 748: 731:Nd:YAG laser 720: 714: 687: 675: 667: 659: 651: 643: 638: 634: 611: 607: 598: 562: 553:lens capsule 547: 545: 530: 515: 500: 496: 487: 483: 444: 436: 425: 421: 415: 411: 384: 378: 375:Pseudophakia 374: 368: 357: 352: 347: 342: 333: 324: 306: 294: 286: 260: 231: 223: 219: 210: 208: 201: 185:near-sighted 182: 179:Medical uses 173: 165: 149: 137:pseudophakic 136: 131: 125:; a form of 102: 98: 96: 93:A phakic IOL 18: 2330:26 February 2299:11 February 2268:11 February 1766:14 February 1739:26 February 1725:www.fda.gov 1100:15 February 727:capsulotomy 683:chromophore 625:Phakic IOLs 585:astigmatism 526:capsulotomy 460:accommodate 369:Aphakic IOL 275:astigmatism 189:far-sighted 141:crystalline 2637:Categories 1705:17 October 1137:8 February 1092:. Healio. 982:References 851:Perspex CQ 830:Plaque at 808:biometrics 779:vitrectomy 697:See also: 565:toric lens 548:Crystalens 474:Multifocal 468:Monovision 464:presbyopic 448:emmetropic 353:Phakic IOL 302:Toric IOLs 193:astigmatic 1602:240712452 1506:26 August 1335:0886-3350 1293:212407635 976:(Germany) 737:Materials 709:slit lamp 456:cataracts 441:Monofocal 115:cataracts 2626:32501896 2422:27039493 2381:11520745 2324:Archived 2293:Archived 2262:Archived 2228:24590672 2171:12498843 2127:19013456 2092:29786830 2043:31101319 2035:21733922 1969:32511121 1917:28003977 1676:24788900 1667:10505746 1594:33373617 1559:25342881 1500:Archived 1400:24937100 1391:10726981 1351:44683984 1343:21111322 1285:32126045 1241:27943250 1132:32644679 1094:Archived 1068:19435692 1060:17172886 1025:23014138 1017:21029908 883:See also 770:silicone 763:collamer 759:acrylate 755:silicone 753:(PMMA), 617:and the 541:silicone 269:glaucoma 252:cataract 156:silicone 42:ICD-9-CM 2617:7299214 2413:6139750 2400:Mo. Med 2372:1724118 2219:4261623 2179:8768209 2083:6494477 1960:7299221 1908:5154990 1815:6525387 1807:7996408 1727:. U.S. 1621:EyeWiki 1550:4206402 1232:6463930 1184:6481478 974:Morcher 951:(USA), 947:(USA), 895:Aphakia 864:during 822:History 775:uveitis 569:corneal 537:zonules 364:Aphakia 105:) is a 60:D054120 2663:Vision 2624:  2614:  2571:29 May 2546:29 May 2521:29 May 2495:29 May 2470:29 May 2445:29 May 2420:  2410:  2379:  2369:  2226:  2216:  2177:  2169:  2125:  2090:  2080:  2041:  2033:  1990:  1967:  1957:  1915:  1905:  1866:2 June 1836:2 June 1813:  1805:  1674:  1664:  1600:  1592:  1557:  1547:  1473:  1433:  1398:  1388:  1349:  1341:  1333:  1291:  1283:  1239:  1229:  1181:  1130:  1066:  1058:  1040:Cornea 1023:  1015:  967:Rayner 949:Eyekon 919:IOLVIP 847:Rayner 791:myopia 579:or an 452:myopic 348:Phakia 298:cornea 290:sulcus 191:, and 132:phakic 2175:S2CID 2039:S2CID 1811:S2CID 1642:(PDF) 1598:S2CID 1347:S2CID 1289:S2CID 1064:S2CID 1021:S2CID 962:(USA) 955:(USA) 945:Alcon 559:Toric 426:ACIOL 416:PCIOL 145:LASIK 78:[ 72:5-984 47:13.72 2622:PMID 2573:2024 2548:2024 2523:2024 2497:2024 2472:2024 2447:2024 2418:PMID 2377:PMID 2332:2023 2301:2023 2270:2023 2224:PMID 2167:PMID 2123:PMID 2088:PMID 2066:2018 2031:PMID 1988:ISBN 1965:PMID 1913:PMID 1868:2017 1838:2017 1803:PMID 1768:2023 1741:2023 1707:2006 1672:PMID 1650:2014 1590:PMID 1555:PMID 1508:2024 1471:ISBN 1431:ISBN 1396:PMID 1374:2014 1339:PMID 1331:ISSN 1281:PMID 1237:PMID 1215:2016 1167:2015 1139:2023 1128:PMID 1102:2023 1056:PMID 1013:PMID 969:(UK) 535:and 358:PIOL 152:PMMA 121:and 107:lens 54:MeSH 2648:Eye 2612:PMC 2604:doi 2408:PMC 2404:113 2367:PMC 2359:doi 2214:PMC 2206:doi 2159:doi 2115:doi 2078:PMC 2070:doi 2021:doi 1955:PMC 1947:doi 1903:PMC 1895:doi 1795:doi 1662:PMC 1654:doi 1582:doi 1578:128 1545:PMC 1535:doi 1463:doi 1423:doi 1386:PMC 1378:doi 1323:doi 1273:doi 1227:PMC 1219:doi 1179:PMC 1171:doi 1048:doi 1005:doi 679:SAD 111:eye 103:IOL 97:An 2639:: 2620:. 2610:. 2598:. 2594:. 2564:. 2539:. 2513:. 2488:. 2463:. 2438:. 2416:. 2402:. 2398:. 2375:. 2365:. 2355:85 2353:. 2349:. 2318:. 2287:. 2256:. 2236:^ 2222:. 2212:. 2200:. 2196:. 2173:. 2165:. 2155:28 2153:. 2121:. 2111:88 2109:. 2086:. 2076:. 2064:. 2060:. 2037:. 2029:. 2017:96 2015:. 2011:. 1963:. 1953:. 1941:. 1937:. 1925:^ 1911:. 1901:. 1889:. 1885:. 1846:^ 1809:. 1801:. 1791:20 1789:. 1785:. 1758:. 1723:. 1693:. 1670:. 1660:. 1648:. 1644:. 1629:^ 1619:. 1596:. 1588:. 1576:. 1553:. 1543:. 1529:. 1525:. 1498:. 1494:. 1469:. 1445:^ 1429:. 1394:. 1384:. 1372:. 1368:. 1345:. 1337:. 1329:. 1319:36 1317:. 1313:. 1301:^ 1287:. 1279:. 1269:46 1267:. 1263:. 1249:^ 1235:. 1225:. 1213:. 1209:. 1193:^ 1177:. 1165:. 1161:. 1147:^ 1122:. 1110:^ 1088:. 1076:^ 1062:. 1054:. 1044:25 1042:. 1019:. 1011:. 1001:36 999:. 971:, 964:, 957:, 300:. 187:, 2628:. 2606:: 2600:9 2575:. 2550:. 2525:. 2499:. 2474:. 2449:. 2424:. 2383:. 2361:: 2334:. 2303:. 2272:. 2230:. 2208:: 2202:3 2181:. 2161:: 2129:. 2117:: 2094:. 2072:: 2045:. 2023:: 1996:. 1971:. 1949:: 1943:9 1919:. 1897:: 1891:9 1870:. 1840:. 1817:. 1797:: 1770:. 1743:. 1709:. 1678:. 1656:: 1604:. 1584:: 1561:. 1537:: 1531:8 1510:. 1479:. 1465:: 1439:. 1425:: 1402:. 1380:: 1353:. 1325:: 1295:. 1275:: 1243:. 1221:: 1187:. 1173:: 1141:. 1104:. 1070:. 1050:: 1027:. 1007:: 711:) 677:( 424:( 414:( 356:( 277:, 271:, 247:, 240:, 101:( 82:]

Index


ICD-9-CM
13.72
MeSH
D054120
OPS-301 code
edit on Wikidata

lens
eye
cataracts
short sightedness
long sightedness
refractive surgery
phakic
crystalline
LASIK
PMMA
silicone
multifocal intraocular lens
ophthalmologist
near-sighted
far-sighted
astigmatic
phakic intraocular lens
excimer laser surgery
clear lens extraction
excimer laser
endothelial cells
retinal detachment

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