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John Buchanan (biologist)

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260:, the MIT president responsible for recruiting Buchanan, described the hire as among the most important and expensive hires he made, because the department's biochemistry division under Buchanan's leadership quickly became widely well-regarded in the field. Later, as biochemistry became more established, Buchanan opposed some of the decisions made in the department, such as the shutdown of the Division of Biochemistry under department head 1312: 1322: 1327: 740: 283:
in 1962. Buchanan became the first John and Dorothy Wilson Professor in 1966 and retained the title till he retired in 1988. In 2006, MIT endowed an annual lectureship in his name.
1332: 910: 760: 1174: 733: 308: 149:. He played a key role in the development of MIT's Department of Biology as a major force in biochemistry research and was himself a prominent researcher of 1228: 1222: 988: 832: 766: 1270: 1258: 970: 856: 838: 1078: 726: 844: 772: 311:, Buchanan's research group made so much progress on this topic that they laid out their findings in a series of over 20 papers published in the 784: 982: 814: 1302: 220:. He became the head of the Division of Biochemistry and quickly began recruiting faculty interested in biochemistry research, including 244:(the first woman faculty member in the department, hired in 1967). He also sought out more senior scientists to bring to MIT, including 1337: 280: 213: 317:. Buchanan and Greenberg's work together provided an understanding of the pathway through which purine bases could be converted to 749: 272: 1317: 713: 363: 276: 142: 138: 114: 426: 1307: 613: 181: 141:. He arrived at MIT in 1953 and retired in 1988 after a distinguished career in which he was elected a fellow of the 172:
as an undergraduate, where he gained his first scientific research experience, and from which he graduated with a
313: 146: 168:, in 1917. He became interested in a career in science during a high school chemistry course. He attended 216:. He had been heavily recruited by the head of what was then called the Department of Molecular Biology, 1144: 667:
Massachusetts Institute of Technology, Department of Distinctive Collections, Cambridge, Massachusetts.
64: 796: 704: 221: 692: 952: 197: 333:. The two were married for 57 years and had four children. Buchanan died in 2007 at age 89. 1297: 1292: 1252: 1192: 1168: 1066: 1018: 173: 718: 8: 1036: 1024: 940: 265: 249: 1198: 1180: 1162: 1120: 886: 564: 539: 484: 459: 217: 193: 443: 1216: 1030: 880: 874: 609: 579: 489: 177: 169: 1126: 1102: 1090: 1006: 862: 808: 790: 559: 551: 479: 471: 438: 165: 46: 1240: 1156: 1150: 1096: 1084: 1054: 826: 629: 261: 245: 185: 1210: 1138: 1114: 1012: 1000: 958: 934: 922: 916: 892: 253: 229: 209: 1286: 1204: 1060: 1048: 976: 964: 946: 820: 606:
Natural Obsessions: Striving to Unlock the Deepest Secrets of the Cancer Cell
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Chen, Lan-Bo; Hartman, Stan; Zetter, Bruce; Zhang, Shuguang (November 2007).
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and the planning under subsequent department head Gene Brown to launch the
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University of Michigan College of Literature, Science, and the Arts alumni
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Kresge, Nicole; Simoni, Robert D.; Hill, Robert L. (3 November 2006).
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Buchanan met his wife Elsa during a visit to Stockholm to work with
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in 1939, and later identified the head of its chemistry department,
188:, as a key influence in his research career. Buchanan received his 291:
Buchanan's graduate research formed one of the earliest uses of
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Massachusetts Institute of Technology School of Science faculty
304: 150: 84: 630:"John M. Buchanan, retired professor and noted biochemist, 89" 189: 748: 427:"Biosynthesis of the Purines: the Work of John M. Buchanan" 208:
Buchanan arrived at MIT in 1953 after reaching the rank of
364:"John Machlin Buchanan (1917–2007): A Biographical Memoir" 1328:
Members of the United States National Academy of Sciences
537: 129:(September 29, 1917 – June 25, 2007) was an American 1333:
Fellows of the American Academy of Arts and Sciences
508:"Colleagues honor Professor Lisa Steiner of biology" 1284: 714:National Academy of Sciences Biographical Memoir 424: 396:"Buchanan looks back on history of biochemistry" 460:"Aspects of nucleotide enzymology and biology" 734: 420: 418: 416: 389: 387: 533: 531: 529: 457: 299:. He is best known for his research on the 159: 741: 727: 413: 384: 281:United States National Academy of Sciences 563: 483: 451: 442: 361: 214:University of Pennsylvania Medical School 526: 750:Eli Lilly Award in Biological Chemistry 622: 273:Eli Lilly Award in Biological Chemistry 1285: 603: 500: 393: 176:in chemistry in 1938. He received his 722: 597: 572: 362:Hartman, Standish C.; Zetter, Bruce. 357: 355: 353: 351: 349: 347: 345: 277:American Academy of Arts and Sciences 143:American Academy of Arts and Sciences 139:Massachusetts Institute of Technology 115:Massachusetts Institute of Technology 394:Halber, Deborah (12 December 2001). 1303:People from Pulaski County, Indiana 13: 342: 203: 16:American professor of biochemistry 14: 1349: 1338:20th-century American biochemists 647: 307:. Often working in parallel with 196:in 1943 under the supervision of 182:University of Michigan, Ann Arbor 324: 431:Journal of Biological Chemistry 314:Journal of Biological Chemistry 275:in 1951. He was elected to the 540:"John M. Buchanan (1917–2007)" 1: 1318:Harvard Medical School alumni 632:. MIT News. 19 September 2007 608:. Houghton Mifflin Harcourt. 458:Buchanan JM (November 1994). 444:10.1016/S0021-9258(20)70562-4 336: 156:. He died in 2007 at age 89. 705:How to use archival material 371:National Academy of Sciences 147:National Academy of Sciences 7: 286: 10: 1354: 756: 687: 679: 671: 663: 271:Buchanan was awarded the 120: 110: 100: 93: 79: 71: 65:Burlington, Massachusetts 53: 28: 21: 1308:DePauw University alumni 683:This collection is open. 604:Angier, Natalie (2014). 160:Early life and education 693:John M. Buchanan papers 476:10.1002/pro.5560031129 953:Charles C. Richardson 198:Albert Baird Hastings 164:Buchanan was born in 127:John Machlin Buchanan 33:John Machlin Buchanan 1217:Christopher J. Chang 1193:Paul J. Hergenrother 1169:Benjamin Cravatt III 1067:Jacqueline K. Barton 1019:Christopher T. Walsh 584:MIT Infinite History 1175:Dewey G. McCafferty 1103:Stuart L. Schreiber 1037:Harold M. Weintraub 941:Phillips W. Robbins 309:G. Robert Greenberg 279:in 1953 and to the 266:Whitehead Institute 1199:Scott K. Silverman 1181:Linda Hsieh-Wilson 1163:Andreas Matouschek 1121:Gregory L. Verdine 1085:George L. McLendon 887:Harold A. Scheraga 797:Earl A. Evans, Jr. 556:10.1002/pro.162578 218:Francis O. Schmitt 194:Harvard University 43:September 29, 1917 1280: 1279: 1253:Bradley Pentelute 1223:Matthew D. Disney 1031:Roger D. Kornberg 1013:Charles R. Cantor 989:James E. Dahlberg 959:Mario R. Capecchi 935:Gerald M. Edelman 923:William P. Jencks 881:Robert A. Alberty 875:William F. Neuman 803:Herbert E. Carter 710: 709: 699: 698: 550:(11): 2578–2579. 174:bachelor's degree 170:DePauw University 124: 123: 95:Scientific career 1345: 1127:Alanna Schepartz 1091:Peter G. Schultz 1061:James E. Rothman 1049:David V. Goeddel 1025:Phillip A. Sharp 1007:Robert G. Roeder 977:Bruce M. Alberts 947:Gordon G. Hammes 863:Nathan O. Kaplan 851:John M. Buchanan 833:Dilworth Woodley 809:Joseph S. Fruton 791:David Rittenberg 767:Harold S. Alcott 761:William M. Allen 743: 736: 729: 720: 719: 695: 661: 660: 652: 651: 642: 641: 639: 637: 626: 620: 619: 601: 595: 594: 592: 590: 576: 570: 569: 567: 535: 524: 523: 521: 519: 504: 498: 497: 487: 455: 449: 448: 446: 437:(e35): e35–e36. 422: 411: 410: 408: 406: 391: 382: 381: 379: 377: 368: 359: 166:Winamac, Indiana 60: 47:Winamac, Indiana 42: 40: 19: 18: 1353: 1352: 1348: 1347: 1346: 1344: 1343: 1342: 1283: 1282: 1281: 1276: 1271:Jordan L. Meier 1259:Neal K. Devaraj 1241:Elizabeth Nolan 1157:Kevan M. Shokat 1151:Jennifer Doudna 1097:William DeGrado 1055:Gerald M. Rubin 971:David F. Wilson 911:Frederick Crane 857:David M. Bonner 839:Irving M. Klotz 827:Sidney Colowick 752: 747: 691: 650: 645: 635: 633: 628: 627: 623: 616: 602: 598: 588: 586: 580:"Gene M. Brown" 578: 577: 573: 544:Protein Science 536: 527: 517: 515: 506: 505: 501: 456: 452: 423: 414: 404: 402: 392: 385: 375: 373: 366: 360: 343: 339: 327: 289: 262:Boris Magasanik 246:Cyrus Levinthal 206: 204:Academic career 186:Howard B. Lewis 162: 67: 62: 58: 49: 44: 38: 36: 35: 34: 24: 17: 12: 11: 5: 1351: 1341: 1340: 1335: 1330: 1325: 1320: 1315: 1310: 1305: 1300: 1295: 1278: 1277: 1275: 1274: 1268: 1262: 1256: 1250: 1244: 1238: 1232: 1226: 1220: 1214: 1211:Nathanael Gray 1208: 1202: 1196: 1190: 1184: 1178: 1172: 1166: 1160: 1154: 1148: 1142: 1139:Chaitan Khosla 1136: 1130: 1124: 1118: 1115:Jeremy M. Berg 1112: 1106: 1100: 1094: 1088: 1082: 1079:Michael M. Cox 1076: 1070: 1064: 1058: 1052: 1046: 1040: 1034: 1028: 1022: 1016: 1010: 1004: 1001:Joan A. Steitz 998: 992: 986: 980: 974: 968: 962: 956: 950: 944: 938: 932: 926: 920: 917:Jerard Hurwitz 914: 908: 902: 896: 893:Lester J. Reed 890: 884: 878: 872: 866: 860: 854: 848: 842: 836: 830: 824: 818: 815:Max A. Lauffer 812: 806: 800: 794: 788: 782: 776: 770: 764: 757: 754: 753: 746: 745: 738: 731: 723: 717: 716: 708: 707: 701: 700: 697: 696: 689: 685: 684: 681: 677: 676: 673: 669: 668: 665: 657: 656: 649: 648:External links 646: 644: 643: 621: 614: 596: 571: 525: 499: 470:(11): 2151–7. 450: 412: 383: 340: 338: 335: 326: 323: 288: 285: 254:Alexander Rich 230:Salvador Luria 210:full professor 205: 202: 161: 158: 122: 121: 118: 117: 112: 108: 107: 102: 98: 97: 91: 90: 81: 80:Known for 77: 76: 73: 69: 68: 63: 61:(aged 89) 55: 51: 50: 45: 32: 30: 26: 25: 22: 15: 9: 6: 4: 3: 2: 1350: 1339: 1336: 1334: 1331: 1329: 1326: 1324: 1321: 1319: 1316: 1314: 1311: 1309: 1306: 1304: 1301: 1299: 1296: 1294: 1291: 1290: 1288: 1272: 1269: 1266: 1263: 1260: 1257: 1254: 1251: 1248: 1245: 1242: 1239: 1236: 1233: 1230: 1227: 1224: 1221: 1218: 1215: 1212: 1209: 1206: 1205:Alice Y. Ting 1203: 1200: 1197: 1194: 1191: 1188: 1185: 1182: 1179: 1176: 1173: 1170: 1167: 1164: 1161: 1158: 1155: 1152: 1149: 1146: 1145:Xiaodong Wang 1143: 1140: 1137: 1134: 1131: 1128: 1125: 1122: 1119: 1116: 1113: 1110: 1107: 1104: 1101: 1098: 1095: 1092: 1089: 1086: 1083: 1080: 1077: 1074: 1071: 1068: 1065: 1062: 1059: 1056: 1053: 1050: 1047: 1044: 1041: 1038: 1035: 1032: 1029: 1026: 1023: 1020: 1017: 1014: 1011: 1008: 1005: 1002: 999: 996: 993: 990: 987: 984: 981: 978: 975: 972: 969: 966: 965:Lubert Stryer 963: 960: 957: 954: 951: 948: 945: 942: 939: 936: 933: 930: 927: 924: 921: 918: 915: 912: 909: 906: 903: 900: 897: 894: 891: 888: 885: 882: 879: 876: 873: 870: 867: 864: 861: 858: 855: 852: 849: 846: 845:William Shive 843: 840: 837: 834: 831: 828: 825: 822: 821:John D. Ferry 819: 816: 813: 810: 807: 804: 801: 798: 795: 792: 789: 786: 783: 780: 777: 774: 773:Abraham White 771: 768: 765: 762: 759: 758: 755: 751: 744: 739: 737: 732: 730: 725: 724: 721: 715: 712: 711: 706: 703: 702: 694: 690: 686: 682: 678: 674: 670: 666: 662: 659: 658: 654: 653: 631: 625: 617: 615:9780544358348 611: 607: 600: 585: 581: 575: 566: 561: 557: 553: 549: 545: 541: 534: 532: 530: 514:. 30 May 2008 513: 509: 503: 495: 491: 486: 481: 477: 473: 469: 465: 461: 454: 445: 440: 436: 432: 428: 421: 419: 417: 401: 397: 390: 388: 372: 365: 358: 356: 354: 352: 350: 348: 346: 341: 334: 332: 331:Hugo Theorell 325:Personal life 322: 320: 316: 315: 310: 306: 302: 298: 295:for studying 294: 293:radiolabeling 284: 282: 278: 274: 269: 267: 263: 259: 258:James Killian 255: 251: 247: 243: 239: 235: 234:Paul Schimmel 231: 227: 226:Vernon Ingram 223: 219: 215: 211: 201: 199: 195: 191: 187: 183: 179: 175: 171: 167: 157: 155: 152: 148: 144: 140: 136: 132: 128: 119: 116: 113: 109: 106: 103: 99: 96: 92: 89: 86: 82: 78: 74: 70: 66: 57:June 25, 2007 56: 52: 48: 31: 27: 23:John Buchanan 20: 1187:Anna K. Mapp 1133:John Kuriyan 1109:Peter S. Kim 1073:Peter Walter 1043:Richard Axel 995:Mark Ptashne 905:James Watson 869:Harvey Itano 850: 785:Eric G. Ball 634:. Retrieved 624: 605: 599: 587:. Retrieved 583: 574: 547: 543: 516:. Retrieved 511: 502: 467: 463: 453: 434: 430: 403:. Retrieved 399: 374:. Retrieved 370: 328: 312: 301:biosynthesis 290: 270: 242:Lisa Steiner 238:Phil Robbins 207: 163: 154:biosynthesis 135:biochemistry 126: 125: 111:Institutions 105:Biochemistry 94: 88:biosynthesis 59:(2007-06-25) 1298:2007 deaths 1293:1917 births 1247:Howard Hang 983:C. Fred Fox 779:George Wald 672:Identifiers 655:Archives at 464:Protein Sci 319:nucleotides 250:Maurice Fox 72:Nationality 1287:Categories 1235:Minkui Luo 929:Bruce Ames 337:References 297:metabolism 222:Gene Brown 39:1917-09-29 1265:Yimon Aye 899:Paul Berg 180:from the 131:professor 83:Study of 664:Location 636:11 April 589:1 August 518:2 August 512:MIT News 405:3 August 400:MIT News 376:2 August 287:Research 145:and the 75:American 1229:Yi Tang 675:MC-0650 565:2211695 494:7703861 485:2142634 305:purines 212:at the 137:at the 1273:(2021) 1267:(2020) 1261:(2019) 1255:(2018) 1249:(2017) 1243:(2016) 1237:(2015) 1231:(2014) 1225:(2013) 1219:(2012) 1213:(2011) 1207:(2010) 1201:(2009) 1195:(2008) 1189:(2007) 1183:(2006) 1177:(2005) 1171:(2004) 1165:(2003) 1159:(2002) 1153:(2001) 1147:(2000) 1141:(1999) 1135:(1998) 1129:(1997) 1123:(1996) 1117:(1995) 1111:(1994) 1105:(1993) 1099:(1992) 1093:(1991) 1087:(1990) 1081:(1989) 1075:(1988) 1069:(1987) 1063:(1986) 1057:(1985) 1051:(1984) 1045:(1983) 1039:(1982) 1033:(1981) 1027:(1980) 1021:(1979) 1015:(1978) 1009:(1977) 1003:(1976) 997:(1975) 991:(1974) 985:(1973) 979:(1972) 973:(1971) 967:(1970) 961:(1969) 955:(1968) 949:(1967) 943:(1966) 937:(1965) 931:(1964) 925:(1963) 919:(1962) 913:(1961) 907:(1960) 901:(1959) 895:(1958) 889:(1957) 883:(1956) 877:(1955) 871:(1954) 865:(1953) 859:(1952) 853:(1951) 847:(1950) 841:(1949) 835:(1948) 829:(1947) 823:(1946) 817:(1945) 811:(1944) 805:(1943) 799:(1942) 793:(1941) 787:(1940) 781:(1939) 775:(1938) 769:(1937) 763:(1935) 688:Source 680:Access 612:  562:  492:  482:  151:purine 101:Fields 85:purine 367:(PDF) 192:from 190:Ph.D. 638:2011 610:ISBN 591:2016 520:2016 490:PMID 407:2016 378:2016 252:and 240:and 178:M.S. 54:Died 29:Born 560:PMC 552:doi 480:PMC 472:doi 439:doi 435:281 303:of 133:of 1289:: 582:. 558:. 548:16 546:. 542:. 528:^ 510:. 488:. 478:. 466:. 462:. 433:. 429:. 415:^ 398:. 386:^ 369:. 344:^ 321:. 268:. 256:. 248:, 236:, 232:, 228:, 224:, 200:. 742:e 735:t 728:v 640:. 618:. 593:. 568:. 554:: 522:. 496:. 474:: 468:3 447:. 441:: 409:. 380:. 41:) 37:(

Index

Winamac, Indiana
Burlington, Massachusetts
purine
biosynthesis
Biochemistry
Massachusetts Institute of Technology
professor
biochemistry
Massachusetts Institute of Technology
American Academy of Arts and Sciences
National Academy of Sciences
purine
biosynthesis
Winamac, Indiana
DePauw University
bachelor's degree
M.S.
University of Michigan, Ann Arbor
Howard B. Lewis
Ph.D.
Harvard University
Albert Baird Hastings
full professor
University of Pennsylvania Medical School
Francis O. Schmitt
Gene Brown
Vernon Ingram
Salvador Luria
Paul Schimmel
Phil Robbins

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