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Kainic acid

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333: 42: 673: 526: 633:. Chemical stimulation, while more complicated than electrical stimulation, has the distinct advantage of activating cell bodies, but not nearby axons, because only cell bodies and subsequent dendrites contain glutamate receptors. Therefore, chemical stimulation by kainic acid is more localized than electrical stimulation. Both chemical and electrical 628:
Electrical stimulation of designated areas of the brain are generally administered by passing an electric current through a wire that is inserted into the brain to lesion a particular area of the brain. Electrical stimulation indiscriminately destroys anything in the vicinity of the electrode tip,
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subunit and also through activation of AMPA receptors, for which it serves as a partial agonist. Also, infusion with kainic acid in the hippocampus of animals results in major damage of pyramidal neurons and subsequent seizure activity. Supply shortages beginning in 2000 have caused the cost of
4454: 4449: 669:-dimethylallyl-l-glutamic acid (prekainic acid). KabC then catalyzes the stereocontrolled formation of the trisubstituted pyrrolidine ring, taking prekainic acid to the final kainic acid. KabC was also able to produce another kainic acid isomer, kainic acid lactone. 724:
excitant that is used in epilepsy research to induce seizures in experimental animals, at a typical dose of 10–30 mg/kg in mice. In addition to inducing seizures, kainic acid is excitotoxic and epileptogenic. Kainic acid induces seizures via activation of
658:) genes. This cluster contains an annotated N-prenyltransferase, α-ketoglutarate (αKG)-dependent dioxygenase, and several retrotransposable elements. To confirm production of kainic acid through the identified cluster, Chekan et al. expressed the genes in 624:
lesion. Thus, in large, concentrated doses kainic acid can be considered a neurotoxin, and in small doses of dilute solution kainic acid will chemically stimulate neurons. In fact, kainate seems to regulate serotonergic activity in the vertebrate retina.
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including neural bodies and axons of neurons passing through; therefore it is difficult to attribute the effects of the lesion to a single area. Chemical stimulation is typically administered through a cannula that is inserted into the brain via
2340: 620:. Kainic acid is a direct agonist of the glutamic kainate receptors and large doses of concentrated solutions produce immediate neuronal death by overstimulating neurons to death. Such damage and death of neurons is referred to as an 641:
are performed in comparison to a sham lesion that duplicates all the steps of producing a brain lesion except the one that actually causes the brain damage, that is, injection of kainic acid or administration of an electrical shock.
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Kainic acid is utilised in primary neuronal cell cultures and in the acute brain slice preparation to study the physiological effect of excitotoxicity and assess the neuroprotective capabilities of potential therapeutics.
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Craig AJ, Housley GD, Fath T (2014). "Modeling excitotoxic ischemic brain injury of cerebellar Purkinje neurons by intravital and in vitro multi-photon laser scanning microscopy.". In Bakota L, Brandt R (eds.).
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The first step of the pathway involves the N-prenyltransferase, KabA, which allows for the prenylation of L-glutamic acid with dimethylallyl pyrophosphate (DMAPP) to form the intermediate
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Passos AD, Herculano AM, Oliveira KR, de Lima SM, Rocha FA, Freitas HR, et al. (October 2019). "Regulation of the Serotonergic System by Kainate in the Avian Retina".
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Meade AJ, Meloni BP, Mastaglia FL, Watt PM, Knuckey NW (November 2010). "AP-1 inhibitory peptides attenuate in vitro cortical neuronal cell death induced by kainic acid".
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potentially cause additional damage to the brain due to the very nature of the inserted electrode or cannula. Therefore, the most effective
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in the central nervous system. Glutamate is produced by the cell's metabolic processes and there are four major classifications of
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A study of the changes in dentate granule cell excitability and inhibition in the kainic acid model of temporal lobe epilepsy
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A study of the changes in dentate granule cell excitability and inhibition in the kainic acid model of temporal lobe epilepsy
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In 2019, Chekan et al. were able to use bioinformatic tools to look for domoic acid gene homologs in the seaweed
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InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)
328: 251: 5055: 4973: 4867: 3224: 17: 4350: 654:. Researchers identified a cluster containing genes identified as the kainic acid biosynthesis ( 4958: 4597: 4464: 3509: 3375: 3099: 2574: 2367: 2179: 2170: 759: 721: 638: 617: 5090: 5060: 4391: 4388: 3300: 3094: 449: 54: 836: 803: 5065: 4935: 2217: 1932: 1673: 1249: 630: 299: 220: 8: 4991: 4925: 4880: 4798: 2579: 1985: 1412: 1310: 837: 804: 582: 124: 114: 4476: 3146: 1116:"Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis" 332: 180: 4948: 4439: 3670: 3334: 2522: 2517: 2357: 2201: 1283: 1240: 1237: 1140: 1115: 1020: 937: 912: 893: 773: 616:
Kainic acid is commonly injected into laboratory animal models to study the effects of
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Chekan JR, McKinnie SM, Moore ML, Poplawski SG, Michael TP, Moore BS (June 2019).
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Laser scanning microscopy and quantitative image analysis of neuronal tissue
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Tooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
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Fritsch B, Reis J, Gasior M, Kaminski RM, Rogawski MA (April 2014).
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Except where otherwise noted, data are given for materials in their
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coli and validated the enzymatic functions of each proposed gene.
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Uncompetitive pore blockers (mostly dizocilpine site):
569:. Kainic acid is a potent neuroexcitatory amino acid 1943: 700:
in 1953. They are called "Kainin-sou" or "Makuri" in
960:Moloney MG (April 1998). "Excitatory amino acids". 676:
Biosynthesis of kainic acid and kainic acid lactone
444:215 °C (419 °F; 488 K) (decomposes) 102:
2-Carboxy-3-carboxymethyl-4-isopropenyl-pyrrolidine
4781: 27:"Kainate" redirects here. Not to be confused with 1236: 5047: 4828: 1037: 278: 4974: 4868: 123: 4753:Tooltip Glutamine aminohydrolase (glutaminase) 2195: 2180: 4366: 3316: 1265: 685:Kainic acid was originally isolated from the 4936: 1093:Jasper's Basic Mechanisms of the Epilepsies 711: 565:, is an acid that naturally occurs in some 5032:Metabotropic glutamate receptor modulators 4414:Tooltip Excitatory amino acid transporters 4373: 4359: 3323: 3309: 3282:Metabotropic glutamate receptor modulators 1272: 1258: 331: 219: 4335:Glutamate metabolism/transport modulators 4242:Tooltip Metabotropic glutamate receptor 8 4143:Tooltip Metabotropic glutamate receptor 7 4071:Tooltip Metabotropic glutamate receptor 6 3967:Tooltip Metabotropic glutamate receptor 4 3818:Tooltip Metabotropic glutamate receptor 3 3660:Tooltip Metabotropic glutamate receptor 2 3474:Tooltip Metabotropic glutamate receptor 5 3360:Tooltip Metabotropic glutamate receptor 1 3289:Glutamate metabolism/transport modulators 1139: 936: 298: 5036:GABA metabolism and transport modulators 5028:Ionotropic glutamate receptor modulators 4571:Tooltip Vesicular glutamate transporters 4331:Ionotropic glutamate receptor modulators 1701: 1175:. Chemical and Engineering News: 14–15. 1162: 671: 1169:Chemical & Engineering News Archive 1086: 959: 834: 801: 327: 256: 66:)-3-(Carboxymethyl)-4-(prop-1-en-2-yl)- 14: 5048: 3012:Alcohols/volatile anesthetics/related: 593:receptors, kainate receptors, and the 573:that acts by activating receptors for 4608:Amido black 10B (naphthol blue black) 4354: 3304: 2168:Other positive allosteric modulators: 1948:Tooltip N-Methyl-D-aspartate receptor 1253: 1235: 605:. Kainate receptors likely control a 359:Key: VLSMHEGGTFMBBZ-UHFFFAOYSA-N 199: 179: 3874:Pomaglumetad methionil (LY-2140023) 3726:Pomaglumetad methionil (LY-2140023) 2909:Ifenprodil (NR2B) site antagonists: 870:Cellular and Molecular Neurobiology 734:kainic acid to rise significantly. 269: 239: 24: 4786:Tooltip Aspartate aminotransferase 1473:Pesampator (BIIB-104, PF-04958242) 1200: 1063: 611:excitatory postsynaptic potentials 25: 5107: 1220: 4833:Tooltip Alanine aminotransferase 597:. Kainic acid is an agonist for 595:metabotropic glutamate receptors 524: 413: 407: 40: 4979:Tooltip Glutamate decarboxylase 4873:Tooltip Glutamate dehydrogenase 4270:Positive allosteric modulators: 4221:Negative allosteric modulators: 4010:Positive allosteric modulators: 3928:Negative allosteric modulators: 3792:Negative allosteric modulators: 3735:Positive allosteric modulators: 3591:Negative allosteric modulators: 3534:Positive allosteric modulators: 3332:Metabotropic glutamate receptor 2949:Rislenemdaz (CERC-301, MK-0657) 1896:Negative allosteric modulators: 1784:Positive allosteric modulators: 1607:Negative allosteric modulators: 1360:Positive allosteric modulators: 1194: 1156: 1107: 737: 645: 520:(at 25 °C , 100 kPa). 4964:Phosphinothricin (glufosinate) 2185:Tooltip Dehydroepiandrosterone 1493:Tulrampator (S-47445, CX-1632) 1388:Farampator (CX-691, ORG-24448) 1132:10.1523/JNEUROSCI.5307-13.2014 1080: 1057: 1043:. Springer. pp. 105–128. 1031: 1009:10.1016/j.brainres.2010.09.007 988: 953: 904: 861: 828: 795: 613:(EPSPs) when glutamate binds. 416: 401: 13: 1: 5024:Receptor/signaling modulators 4327:Receptor/signaling modulators 3275:Receptor/signaling modulators 3124:Unknown/unsorted antagonists: 1688:Unknown/unsorted antagonists: 1281:Ionotropic glutamate receptor 789: 680: 603:ionotropic glutamate receptor 4941:Tooltip Glutamine synthetase 7: 2973:NR2A-selective antagonists: 2505:Polyamine site antagonists: 1730:Acromelic acid (acromelate) 1316:Acromelic acid (acromelate) 1120:The Journal of Neuroscience 767: 577:, the principal excitatory 10: 5112: 1413:Hydrochlorothiazide (HCTZ) 882:10.1007/s10571-019-00701-8 26: 5076:Kainate receptor agonists 5017: 4972: 4934: 4866: 4826: 4779: 4746: 4737: 4667:Glutamic acid (glutamate) 4633:Aspartic acid (aspartate) 4564: 4488:-CCG-III ((2S,3S,4R)-CCG) 4445:Glutamic acid (glutamate) 4427:Aspartic acid (aspartate) 4407: 4398: 4320: 4232: 4133: 4061: 3957: 3948: 3859:LY-404,039 (pomaglumetad) 3808: 3706:LY-404,039 (pomaglumetad) 3650: 3641: 3464: 3350: 3341: 3266: 2355:Glycine site antagonists: 1941: 1699: 1290: 1247: 1181:10.1021/cen-v078n001.p014 514: 497: 388: 380:OC(=O)1NC(C(C)=C)1CC(=O)O 368: 343: 107: 99: 75: 53: 48: 39: 4987:3-Mercaptopropionic acid 4496:-Serine-O-sulphate (SOS) 3738:JNJ-40411813 (ADX-71149) 2243:Competitive antagonists: 2151:Polyamine site agonists: 2137:Neboglamine (nebostinel) 1706:Tooltip Kainate receptor 720:Kainic acid is a potent 712:Pharmacological activity 4794:2-Amino-3-butenoic acid 4588:6-(4'-Phenylstyryl)-QDC 4472:-3-Hydroxyaspartic acid 3225:Pentamidine isethionate 2969:Traxoprodil (CP-101606) 2208:Epipregnanolone sulfate 962:Natural Product Reports 749:neurodegenerative agent 4959:Methionine sulfoximine 4546:-3-Methylglutamic acid 3255:Allosteric modulators: 3190:Ipenoxazone (MLV-6976) 2845:Pethidine (meperidine) 2466:Licostinel (ACEA-1021) 2388:Apimostinel (NRX-1074) 2052:Apimostinel (NRX-1074) 2020:Glycine site agonists: 1852:Licostinel (ACEA-1021) 1563:Licostinel (ACEA-1021) 1448:Mibampator (LY-451395) 929:10.1002/anie.201902910 839:Physiology of Behavior 806:Physiology of Behavior 722:central nervous system 677: 5096:Isopropenyl compounds 2924:CO-101244 (PD-174494) 2640:Delucemine (NPS-1506) 2590:Alazocine (SKF-10047) 704:, and are used as an 675: 618:experimental ablation 77:Systematic IUPAC name 4813:-Methylene-aspartate 2944:Radiprodil (RGH-896) 2919:Buphenine (nylidrin) 2496:Rapastinel (GLYX-13) 2311:Midafotel (d-CPPene) 2218:Pregnenolone sulfate 2142:Rapastinel (GLYX-13) 1933:Pregnenolone sulfate 1674:Pregnenolone sulfate 1163:Tremblay JF (2000). 843:. Pearson. pp.  810:. Pearson. pp.  631:stereotactic surgery 4926:Pyridoxal phosphate 4628:Chicago sky blue 6B 4593:6-Biphenyl-4-yl-QDC 2175:-Hydroxycholesterol 1986:Homoquinolinic acid 1959:Main site agonists: 1717:Main site agonists: 1311:5-Fluorowillardiine 1308:Main site agonists: 835:Carlson NR (2013). 802:Carlson NR (2013). 760:Alzheimer's disease 583:glutamate receptors 434: g·mol 161:Beilstein Reference 36: 5071:Marine neurotoxins 4949:2-Aminoadipic acid 4818:Hydrazinosuccinate 2523:Diethylenetriamine 2202:prasterone sulfate 1977:Homocysteic acid ( 1720:5-Bromowillardiine 1238:Glutamate receptor 1087:Ben-Ari Y (2012). 774:Dihydrokainic acid 678: 547:Infobox references 34: 5086:Toxic amino acids 5043: 5042: 5013: 5012: 4999: 4733: 4732: 4651: 4648:Erythro-4-methyl- 4582: 4503: 4495: 4487: 4479: 4467: 4348: 4347: 4342: 4341: 4316: 4315: 4265: 4166: 4089: 3985: 3944: 3943: 3637: 3636: 3298: 3297: 3149: 3105:Trichloroethylene 3050:Ethanol (alcohol) 2415: 2358:4-Cl-KYN (AV-101) 2126: 2118: 2085: 2077: 2069: 2026: 2011:Tetrazolylglycine 1980: 1918:Ethanol (alcohol) 1907:sodium thiopental 1725:5-Iodowillardiine 1634:Ethanol (alcohol) 1618:sodium thiopental 1227:Kainate Receptors 1126:(17): 5765–5775. 1050:978-1-4939-0380-1 923:(25): 8454–8457. 917:Angewandte Chemie 854:978-0-205-23939-9 821:978-0-205-23939-9 727:kainate receptors 599:kainate receptors 555:Chemical compound 553: 552: 505:Crystal structure 312:CompTox Dashboard 149:Interactive image 69: 16:(Redirected from 5103: 5081:Chelating agents 4997: 4980: 4976: 4942: 4938: 4874: 4870: 4858:Propargylglycine 4852: 4844: 4834: 4830: 4812: 4787: 4783: 4754: 4750: 4744: 4743: 4725:Xanthurenic acid 4649: 4618:Benzopurpurin 4B 4580: 4572: 4568: 4501: 4493: 4485: 4477: 4465: 4415: 4411: 4405: 4404: 4375: 4368: 4361: 4352: 4351: 4263: 4243: 4239: 4164: 4144: 4140: 4087: 4072: 4068: 3983: 3968: 3964: 3955: 3954: 3819: 3815: 3661: 3657: 3648: 3647: 3475: 3471: 3361: 3357: 3348: 3347: 3325: 3318: 3311: 3302: 3301: 3147: 3100:Trichloroethanol 2660:Dextromethorphan 2413: 2197: 2186: 2182: 2124: 2116: 2083: 2075: 2067: 2024: 1978: 1949: 1945: 1707: 1703: 1538:Fanapanel (MPQX) 1298: 1294: 1274: 1267: 1260: 1251: 1250: 1233: 1232: 1215: 1214: 1198: 1192: 1191: 1189: 1187: 1160: 1154: 1153: 1143: 1111: 1105: 1104: 1084: 1078: 1077: 1061: 1055: 1054: 1035: 1029: 1028: 992: 986: 985: 974:10.1039/a815205y 957: 951: 950: 940: 908: 902: 901: 876:(7): 1039–1049. 865: 859: 858: 842: 832: 826: 825: 809: 799: 784:Kainate receptor 639:ablation studies 579:neurotransmitter 537: 531: 528: 527: 433: 418: 415: 409: 403: 396:Chemical formula 336: 335: 320: 318: 302: 282: 271: 260: 243: 223: 203: 183: 151: 127: 67: 44: 37: 33: 21: 5111: 5110: 5106: 5105: 5104: 5102: 5101: 5100: 5046: 5045: 5044: 5039: 5009: 4978: 4968: 4940: 4930: 4911:Hexachlorophene 4872: 4862: 4850: 4842: 4832: 4822: 4810: 4785: 4775: 4752: 4729: 4692:Reactive blue 2 4570: 4560: 4413: 4394: 4379: 4349: 4344: 4343: 4338: 4312: 4241: 4238: 4228: 4142: 4139: 4129: 4070: 4067: 4057: 3966: 3963: 3940: 3817: 3814: 3804: 3659: 3656: 3633: 3525:Quisqualic acid 3473: 3470: 3460: 3391:Quisqualic acid 3359: 3356: 3337: 3329: 3299: 3294: 3262: 3160:Flufenamic acid 3095:Trichloroethane 2870:Rhynchophylline 2790:Methoxphenidine 2755:Levomilnacipran 2655:Dextromethadone 2580:α-Endopsychosin 2184: 2096:Dimethylglycine 2006:Quinolinic acid 1947: 1937: 1775:Quisqualic acid 1705: 1695: 1351:Quisqualic acid 1296: 1286: 1278: 1243: 1223: 1218: 1199: 1195: 1185: 1183: 1161: 1157: 1112: 1108: 1085: 1081: 1062: 1058: 1051: 1036: 1032: 993: 989: 958: 954: 909: 905: 866: 862: 855: 833: 829: 822: 800: 796: 792: 770: 740: 729:containing the 714: 697:Chondria armata 691:Digenea simplex 683: 652:Digenea simplex 648: 556: 549: 544: 543: 542:  ?) 533: 529: 525: 521: 507: 489: 471: 431: 421: 412: 406: 398: 384: 381: 376: 375: 364: 361: 360: 357: 351: 350: 339: 321: 314: 305: 285: 272: 246: 226: 206: 186: 163: 154: 141: 130: 117: 103: 95: 94: 71: 32: 23: 22: 15: 12: 11: 5: 5109: 5099: 5098: 5093: 5088: 5083: 5078: 5073: 5068: 5063: 5058: 5056:Glutamic acids 5041: 5040: 5018: 5015: 5014: 5011: 5010: 5008: 5007: 5002: 4994: 4989: 4983: 4981: 4970: 4969: 4967: 4966: 4961: 4956: 4951: 4945: 4943: 4932: 4931: 4929: 4928: 4923: 4918: 4913: 4908: 4903: 4898: 4893: 4888: 4883: 4877: 4875: 4864: 4863: 4861: 4860: 4855: 4847: 4837: 4835: 4824: 4823: 4821: 4820: 4815: 4806: 4801: 4796: 4790: 4788: 4777: 4776: 4774: 4773: 4768: 4763: 4757: 4755: 4741: 4735: 4734: 4731: 4730: 4728: 4727: 4722: 4717: 4712: 4704: 4699: 4694: 4689: 4684: 4679: 4674: 4672:Kynurenic acid 4669: 4664: 4659: 4654: 4652:-glutamic acid 4645: 4643:Direct blue 71 4640: 4635: 4630: 4625: 4620: 4615: 4613:Bafilomycin A1 4610: 4605: 4600: 4595: 4590: 4585: 4575: 4573: 4562: 4561: 4559: 4558: 4553: 4548: 4540: 4535: 4530: 4525: 4520: 4515: 4510: 4498: 4490: 4482: 4474: 4462: 4457: 4452: 4447: 4442: 4437: 4429: 4424: 4418: 4416: 4402: 4396: 4395: 4378: 4377: 4370: 4363: 4355: 4346: 4345: 4340: 4339: 4321: 4318: 4317: 4314: 4313: 4311: 4310: 4305: 4300: 4295: 4290: 4285: 4276: 4275: 4260: 4255: 4246: 4244: 4236: 4230: 4229: 4227: 4226: 4214: 4209: 4204: 4199: 4194: 4189: 4184: 4175: 4174: 4169: 4161: 4156: 4147: 4145: 4137: 4131: 4130: 4128: 4127: 4122: 4117: 4112: 4107: 4102: 4093: 4092: 4084: 4075: 4073: 4065: 4059: 4058: 4056: 4055: 4050: 4045: 4040: 4035: 4030: 4021: 4020: 4015: 4003: 3998: 3993: 3988: 3980: 3971: 3969: 3961: 3952: 3946: 3945: 3942: 3941: 3939: 3938: 3933: 3921: 3916: 3911: 3906: 3901: 3896: 3891: 3882: 3881: 3876: 3871: 3866: 3861: 3856: 3851: 3846: 3841: 3836: 3831: 3822: 3820: 3812: 3806: 3805: 3803: 3802: 3797: 3785: 3780: 3775: 3770: 3765: 3760: 3755: 3750: 3741: 3740: 3728: 3723: 3718: 3713: 3708: 3703: 3698: 3693: 3688: 3683: 3678: 3673: 3664: 3662: 3654: 3645: 3639: 3638: 3635: 3634: 3632: 3631: 3626: 3621: 3616: 3611: 3606: 3601: 3596: 3584: 3579: 3574: 3569: 3564: 3559: 3554: 3549: 3540: 3539: 3527: 3522: 3517: 3512: 3507: 3502: 3497: 3492: 3487: 3478: 3476: 3468: 3462: 3461: 3459: 3458: 3453: 3448: 3443: 3438: 3433: 3428: 3419: 3418: 3413: 3408: 3403: 3398: 3393: 3388: 3383: 3378: 3373: 3364: 3362: 3354: 3345: 3339: 3338: 3328: 3327: 3320: 3313: 3305: 3296: 3295: 3293: 3292: 3285: 3278: 3267: 3264: 3263: 3261: 3260: 3248: 3247: 3237: 3232: 3227: 3222: 3217: 3212: 3207: 3202: 3197: 3192: 3187: 3182: 3177: 3172: 3167: 3162: 3157: 3152: 3144: 3139: 3134: 3129: 3117: 3112: 3107: 3102: 3097: 3092: 3087: 3082: 3077: 3072: 3070:Methoxyflurane 3067: 3062: 3057: 3052: 3047: 3042: 3037: 3032: 3027: 3022: 3017: 3005: 3000: 2988: 2983: 2978: 2966: 2961: 2956: 2951: 2946: 2941: 2936: 2931: 2926: 2921: 2916: 2911: 2902: 2897: 2892: 2887: 2882: 2877: 2872: 2867: 2862: 2857: 2852: 2847: 2842: 2837: 2832: 2827: 2822: 2817: 2815:Nitromemantine 2812: 2807: 2802: 2797: 2792: 2787: 2782: 2777: 2772: 2767: 2762: 2757: 2752: 2750:Levomethorphan 2747: 2742: 2737: 2732: 2727: 2722: 2717: 2712: 2707: 2702: 2697: 2692: 2687: 2682: 2677: 2672: 2670:Dieticyclidine 2667: 2662: 2657: 2652: 2650:Dextrallorphan 2647: 2642: 2637: 2632: 2627: 2622: 2617: 2612: 2607: 2605:Argiotoxin-636 2602: 2597: 2592: 2587: 2582: 2577: 2572: 2567: 2562: 2557: 2552: 2547: 2542: 2530: 2525: 2520: 2518:Diaminopropane 2515: 2510: 2498: 2493: 2488: 2483: 2478: 2473: 2468: 2463: 2458: 2453: 2448: 2446:Kynurenic acid 2443: 2438: 2433: 2428: 2423: 2418: 2410: 2405: 2400: 2395: 2390: 2385: 2380: 2375: 2370: 2365: 2360: 2348: 2343: 2338: 2333: 2328: 2323: 2318: 2313: 2308: 2303: 2298: 2293: 2288: 2283: 2278: 2273: 2268: 2263: 2258: 2253: 2248: 2236: 2235: 2230: 2225: 2220: 2215: 2210: 2205: 2192: 2177: 2161: 2156: 2144: 2139: 2134: 2129: 2121: 2113: 2108: 2103: 2098: 2093: 2088: 2080: 2072: 2064: 2059: 2054: 2049: 2044: 2039: 2034: 2029: 2013: 2008: 2003: 1998: 1993: 1988: 1983: 1974: 1969: 1964: 1952: 1950: 1939: 1938: 1936: 1935: 1930: 1925: 1920: 1915: 1910: 1889: 1884: 1879: 1874: 1869: 1864: 1859: 1854: 1849: 1847:Kynurenic acid 1844: 1839: 1834: 1829: 1824: 1819: 1810: 1809: 1804: 1799: 1794: 1789: 1777: 1772: 1767: 1762: 1757: 1752: 1747: 1742: 1737: 1732: 1727: 1722: 1710: 1708: 1697: 1696: 1694: 1693: 1681: 1676: 1671: 1666: 1661: 1656: 1651: 1646: 1641: 1636: 1631: 1626: 1621: 1600: 1595: 1590: 1585: 1580: 1575: 1570: 1565: 1560: 1555: 1553:Kynurenic acid 1550: 1545: 1540: 1535: 1530: 1525: 1520: 1515: 1510: 1505: 1496: 1495: 1490: 1485: 1480: 1475: 1470: 1465: 1460: 1455: 1450: 1445: 1440: 1435: 1430: 1425: 1420: 1415: 1410: 1405: 1400: 1395: 1390: 1385: 1380: 1375: 1370: 1365: 1353: 1348: 1343: 1338: 1333: 1328: 1323: 1318: 1313: 1301: 1299: 1288: 1287: 1277: 1276: 1269: 1262: 1254: 1248: 1245: 1244: 1230: 1229: 1222: 1221:External links 1219: 1217: 1216: 1193: 1155: 1106: 1079: 1056: 1049: 1030: 997:Brain Research 987: 968:(2): 205–219. 952: 903: 860: 853: 827: 820: 793: 791: 788: 787: 786: 781: 776: 769: 766: 765: 764: 763: 762: 756: 750: 739: 736: 713: 710: 682: 679: 647: 644: 609:that produces 607:sodium channel 554: 551: 550: 545: 523: 522: 518:standard state 515: 512: 511: 508: 503: 500: 499: 495: 494: 491: 487: 477: 476: 473: 469: 459: 458: 455: 446: 445: 442: 436: 435: 429: 423: 422: 419: 410: 404: 399: 394: 391: 390: 386: 385: 383: 382: 379: 371: 370: 369: 366: 365: 363: 362: 358: 355: 354: 346: 345: 344: 341: 340: 338: 337: 324: 322: 310: 307: 306: 304: 303: 295: 293: 287: 286: 284: 283: 275: 273: 265: 262: 261: 254: 248: 247: 245: 244: 236: 234: 228: 227: 225: 224: 216: 214: 208: 207: 205: 204: 196: 194: 188: 187: 185: 184: 176: 174: 168: 167: 164: 159: 156: 155: 153: 152: 144: 142: 135: 132: 131: 129: 128: 120: 118: 113: 110: 109: 105: 104: 101: 97: 96: 80: 79: 73: 72: 57: 51: 50: 46: 45: 9: 6: 4: 3: 2: 5108: 5097: 5094: 5092: 5089: 5087: 5084: 5082: 5079: 5077: 5074: 5072: 5069: 5067: 5064: 5062: 5059: 5057: 5054: 5053: 5051: 5038: 5037: 5033: 5029: 5025: 5022: 5016: 5006: 5005:Semicarbazide 5003: 5001: 5000:-Allylglycine 4995: 4993: 4990: 4988: 4985: 4984: 4982: 4977: 4971: 4965: 4962: 4960: 4957: 4955: 4952: 4950: 4947: 4946: 4944: 4939: 4933: 4927: 4924: 4922: 4921:Palmitoyl-CoA 4919: 4917: 4916:Hydroxylamine 4914: 4912: 4909: 4907: 4904: 4902: 4899: 4897: 4894: 4892: 4889: 4887: 4884: 4882: 4879: 4878: 4876: 4871: 4865: 4859: 4856: 4854: 4848: 4846: 4839: 4838: 4836: 4831: 4825: 4819: 4816: 4814: 4807: 4805: 4802: 4800: 4797: 4795: 4792: 4791: 4789: 4784: 4778: 4772: 4769: 4767: 4764: 4762: 4759: 4758: 4756: 4751: 4745: 4742: 4740: 4736: 4726: 4723: 4721: 4718: 4716: 4713: 4711: 4709: 4705: 4703: 4700: 4698: 4695: 4693: 4690: 4688: 4685: 4683: 4680: 4678: 4675: 4673: 4670: 4668: 4665: 4663: 4660: 4658: 4655: 4653: 4646: 4644: 4641: 4639: 4636: 4634: 4631: 4629: 4626: 4624: 4621: 4619: 4616: 4614: 4611: 4609: 4606: 4604: 4601: 4599: 4596: 4594: 4591: 4589: 4586: 4584: 4577: 4576: 4574: 4569: 4563: 4557: 4554: 4552: 4549: 4547: 4545: 4541: 4539: 4536: 4534: 4531: 4529: 4526: 4524: 4521: 4519: 4518:Maslinic acid 4516: 4514: 4511: 4509: 4507: 4499: 4497: 4491: 4489: 4483: 4481: 4475: 4473: 4471: 4463: 4461: 4458: 4456: 4453: 4451: 4448: 4446: 4443: 4441: 4438: 4436: 4434: 4430: 4428: 4425: 4423: 4420: 4419: 4417: 4412: 4406: 4403: 4401: 4397: 4393: 4390: 4386: 4383: 4376: 4371: 4369: 4364: 4362: 4357: 4356: 4353: 4337: 4336: 4332: 4328: 4325: 4319: 4309: 4306: 4304: 4301: 4299: 4296: 4294: 4291: 4289: 4286: 4284: 4281: 4278: 4277: 4274: 4271: 4267: 4261: 4259: 4256: 4254: 4251: 4248: 4247: 4245: 4240: 4231: 4225: 4222: 4218: 4215: 4213: 4210: 4208: 4205: 4203: 4200: 4198: 4195: 4193: 4190: 4188: 4185: 4183: 4180: 4177: 4176: 4173: 4170: 4168: 4162: 4160: 4157: 4155: 4152: 4149: 4148: 4146: 4141: 4132: 4126: 4123: 4121: 4118: 4116: 4113: 4111: 4108: 4106: 4103: 4101: 4098: 4095: 4094: 4091: 4085: 4083: 4080: 4077: 4076: 4074: 4069: 4060: 4054: 4051: 4049: 4046: 4044: 4041: 4039: 4036: 4034: 4031: 4029: 4026: 4023: 4022: 4019: 4016: 4014: 4011: 4007: 4004: 4002: 3999: 3997: 3994: 3992: 3989: 3987: 3981: 3979: 3976: 3973: 3972: 3970: 3965: 3956: 3953: 3951: 3947: 3937: 3934: 3932: 3929: 3925: 3922: 3920: 3917: 3915: 3912: 3910: 3907: 3905: 3902: 3900: 3897: 3895: 3892: 3890: 3887: 3884: 3883: 3880: 3877: 3875: 3872: 3870: 3867: 3865: 3862: 3860: 3857: 3855: 3852: 3850: 3849:Ibotenic acid 3847: 3845: 3842: 3840: 3837: 3835: 3832: 3830: 3827: 3824: 3823: 3821: 3816: 3807: 3801: 3798: 3796: 3793: 3789: 3786: 3784: 3781: 3779: 3776: 3774: 3771: 3769: 3766: 3764: 3761: 3759: 3756: 3754: 3751: 3749: 3746: 3743: 3742: 3739: 3736: 3732: 3729: 3727: 3724: 3722: 3719: 3717: 3714: 3712: 3709: 3707: 3704: 3702: 3699: 3697: 3696:Ibotenic acid 3694: 3692: 3689: 3687: 3684: 3682: 3679: 3677: 3674: 3672: 3669: 3666: 3665: 3663: 3658: 3649: 3646: 3644: 3640: 3630: 3627: 3625: 3622: 3620: 3617: 3615: 3612: 3610: 3607: 3605: 3602: 3600: 3597: 3595: 3592: 3588: 3585: 3583: 3580: 3578: 3575: 3573: 3570: 3568: 3565: 3563: 3560: 3558: 3555: 3553: 3550: 3548: 3545: 3542: 3541: 3538: 3535: 3531: 3528: 3526: 3523: 3521: 3520:Ibotenic acid 3518: 3516: 3513: 3511: 3508: 3506: 3503: 3501: 3498: 3496: 3493: 3491: 3488: 3486: 3483: 3480: 3479: 3477: 3472: 3463: 3457: 3454: 3452: 3449: 3447: 3444: 3442: 3439: 3437: 3436:Cyclothiazide 3434: 3432: 3429: 3427: 3424: 3421: 3420: 3417: 3414: 3412: 3409: 3407: 3404: 3402: 3399: 3397: 3394: 3392: 3389: 3387: 3386:Ibotenic acid 3384: 3382: 3379: 3377: 3374: 3372: 3369: 3366: 3365: 3363: 3358: 3349: 3346: 3344: 3340: 3336: 3333: 3326: 3321: 3319: 3314: 3312: 3307: 3306: 3303: 3291: 3290: 3286: 3284: 3283: 3279: 3277: 3276: 3273: 3269: 3268: 3265: 3259: 3256: 3253: 3250: 3249: 3245: 3241: 3240:Transcrocetin 3238: 3236: 3235:Psychotridine 3233: 3231: 3228: 3226: 3223: 3221: 3218: 3216: 3215:Niflumic acid 3213: 3211: 3208: 3206: 3203: 3201: 3198: 3196: 3193: 3191: 3188: 3186: 3183: 3181: 3178: 3176: 3173: 3171: 3168: 3166: 3163: 3161: 3158: 3156: 3153: 3151: 3145: 3143: 3140: 3138: 3135: 3133: 3130: 3128: 3125: 3121: 3118: 3116: 3113: 3111: 3108: 3106: 3103: 3101: 3098: 3096: 3093: 3091: 3088: 3086: 3083: 3081: 3078: 3076: 3075:Nitrous oxide 3073: 3071: 3068: 3066: 3063: 3061: 3058: 3056: 3053: 3051: 3048: 3046: 3043: 3041: 3040:Diethyl ether 3038: 3036: 3033: 3031: 3028: 3026: 3023: 3021: 3018: 3016: 3013: 3009: 3006: 3004: 3001: 2999: 2996: 2992: 2989: 2987: 2984: 2982: 2979: 2977: 2974: 2970: 2967: 2965: 2962: 2960: 2957: 2955: 2952: 2950: 2947: 2945: 2942: 2940: 2937: 2935: 2932: 2930: 2927: 2925: 2922: 2920: 2917: 2915: 2912: 2910: 2906: 2903: 2901: 2898: 2896: 2895:Tenocyclidine 2893: 2891: 2890:Tabernanthine 2888: 2886: 2883: 2881: 2880:Rolicyclidine 2878: 2876: 2873: 2871: 2868: 2866: 2863: 2861: 2858: 2856: 2855:Phencyclidine 2853: 2851: 2850:Phencyclamine 2848: 2846: 2843: 2841: 2838: 2836: 2833: 2831: 2828: 2826: 2823: 2821: 2818: 2816: 2813: 2811: 2808: 2806: 2803: 2801: 2798: 2796: 2793: 2791: 2788: 2786: 2785:Methoxetamine 2783: 2781: 2778: 2776: 2773: 2771: 2768: 2766: 2763: 2761: 2758: 2756: 2753: 2751: 2748: 2746: 2745:Levomethadone 2743: 2741: 2738: 2736: 2733: 2731: 2728: 2726: 2723: 2721: 2718: 2716: 2713: 2711: 2708: 2706: 2705:Fluorolintane 2703: 2701: 2698: 2696: 2693: 2691: 2688: 2686: 2683: 2681: 2678: 2676: 2673: 2671: 2668: 2666: 2663: 2661: 2658: 2656: 2653: 2651: 2648: 2646: 2643: 2641: 2638: 2636: 2633: 2631: 2628: 2626: 2623: 2621: 2618: 2616: 2613: 2611: 2608: 2606: 2603: 2601: 2598: 2596: 2593: 2591: 2588: 2586: 2583: 2581: 2578: 2576: 2573: 2571: 2568: 2566: 2563: 2561: 2558: 2556: 2553: 2551: 2548: 2546: 2543: 2541: 2538: 2534: 2531: 2529: 2526: 2524: 2521: 2519: 2516: 2514: 2511: 2509: 2506: 2502: 2499: 2497: 2494: 2492: 2489: 2487: 2484: 2482: 2479: 2477: 2474: 2472: 2469: 2467: 2464: 2462: 2459: 2457: 2454: 2452: 2449: 2447: 2444: 2442: 2439: 2437: 2434: 2432: 2429: 2427: 2424: 2422: 2419: 2417: 2411: 2409: 2406: 2404: 2401: 2399: 2396: 2394: 2391: 2389: 2386: 2384: 2381: 2379: 2376: 2374: 2371: 2369: 2366: 2364: 2361: 2359: 2356: 2352: 2349: 2347: 2344: 2342: 2339: 2337: 2334: 2332: 2329: 2327: 2324: 2322: 2319: 2317: 2314: 2312: 2309: 2307: 2304: 2302: 2299: 2297: 2294: 2292: 2289: 2287: 2286:Kaitocephalin 2284: 2282: 2279: 2277: 2274: 2272: 2269: 2267: 2264: 2262: 2259: 2257: 2254: 2252: 2249: 2247: 2244: 2241: 2238: 2237: 2234: 2231: 2229: 2226: 2224: 2221: 2219: 2216: 2214: 2211: 2209: 2206: 2203: 2199: 2193: 2190: 2183: 2178: 2176: 2174: 2169: 2165: 2162: 2160: 2157: 2155: 2152: 2148: 2145: 2143: 2140: 2138: 2135: 2133: 2130: 2128: 2122: 2120: 2114: 2112: 2109: 2107: 2104: 2102: 2099: 2097: 2094: 2092: 2089: 2087: 2081: 2079: 2073: 2071: 2065: 2063: 2060: 2058: 2055: 2053: 2050: 2048: 2045: 2043: 2040: 2038: 2035: 2033: 2030: 2028: 2021: 2017: 2014: 2012: 2009: 2007: 2004: 2002: 1999: 1997: 1994: 1992: 1991:Ibotenic acid 1989: 1987: 1984: 1982: 1975: 1973: 1970: 1968: 1965: 1963: 1960: 1957: 1954: 1953: 1951: 1946: 1940: 1934: 1931: 1929: 1926: 1924: 1921: 1919: 1916: 1914: 1911: 1908: 1904: 1903:pentobarbital 1900: 1897: 1893: 1890: 1888: 1885: 1883: 1880: 1878: 1875: 1873: 1870: 1868: 1865: 1863: 1860: 1858: 1855: 1853: 1850: 1848: 1845: 1843: 1842:Kaitocephalin 1840: 1838: 1835: 1833: 1830: 1828: 1825: 1823: 1820: 1818: 1815: 1812: 1811: 1808: 1805: 1803: 1800: 1798: 1795: 1793: 1790: 1788: 1787:Cyclothiazide 1785: 1781: 1778: 1776: 1773: 1771: 1768: 1766: 1763: 1761: 1758: 1756: 1755:Ibotenic acid 1753: 1751: 1748: 1746: 1743: 1741: 1738: 1736: 1733: 1731: 1728: 1726: 1723: 1721: 1718: 1715: 1712: 1711: 1709: 1704: 1698: 1692: 1689: 1685: 1682: 1680: 1677: 1675: 1672: 1670: 1667: 1665: 1662: 1660: 1657: 1655: 1652: 1650: 1647: 1645: 1642: 1640: 1637: 1635: 1632: 1630: 1627: 1625: 1622: 1619: 1615: 1614:pentobarbital 1611: 1608: 1604: 1601: 1599: 1596: 1594: 1591: 1589: 1586: 1584: 1581: 1579: 1576: 1574: 1571: 1569: 1566: 1564: 1561: 1559: 1556: 1554: 1551: 1549: 1548:Kaitocephalin 1546: 1544: 1541: 1539: 1536: 1534: 1531: 1529: 1526: 1524: 1521: 1519: 1516: 1514: 1511: 1509: 1506: 1504: 1501: 1498: 1497: 1494: 1491: 1489: 1486: 1484: 1481: 1479: 1476: 1474: 1471: 1469: 1466: 1464: 1461: 1459: 1456: 1454: 1451: 1449: 1446: 1444: 1441: 1439: 1436: 1434: 1431: 1429: 1426: 1424: 1421: 1419: 1416: 1414: 1411: 1409: 1406: 1404: 1401: 1399: 1396: 1394: 1391: 1389: 1386: 1384: 1381: 1379: 1376: 1374: 1371: 1369: 1368:Cyclothiazide 1366: 1364: 1361: 1357: 1354: 1352: 1349: 1347: 1344: 1342: 1341:Ibotenic acid 1339: 1337: 1334: 1332: 1329: 1327: 1324: 1322: 1319: 1317: 1314: 1312: 1309: 1306: 1303: 1302: 1300: 1295: 1289: 1285: 1282: 1275: 1270: 1268: 1263: 1261: 1256: 1255: 1252: 1246: 1242: 1239: 1234: 1228: 1225: 1224: 1212: 1208: 1204: 1197: 1182: 1178: 1174: 1170: 1166: 1159: 1151: 1147: 1142: 1137: 1133: 1129: 1125: 1121: 1117: 1110: 1102: 1098: 1094: 1090: 1083: 1075: 1071: 1067: 1060: 1052: 1046: 1042: 1034: 1026: 1022: 1018: 1014: 1010: 1006: 1002: 998: 991: 983: 979: 975: 971: 967: 963: 956: 948: 944: 939: 934: 930: 926: 922: 918: 914: 907: 899: 895: 891: 887: 883: 879: 875: 871: 864: 856: 850: 846: 841: 840: 831: 823: 817: 813: 808: 807: 798: 794: 785: 782: 780: 777: 775: 772: 771: 761: 757: 755: 751: 748: 747: 745: 742: 741: 735: 732: 728: 723: 718: 709: 707: 703: 699: 698: 693: 692: 688: 674: 670: 668: 663: 661: 657: 653: 643: 640: 636: 632: 626: 623: 619: 614: 612: 608: 604: 600: 596: 592: 588: 584: 580: 576: 572: 568: 564: 560: 548: 541: 536: 519: 513: 509: 506: 502: 501: 496: 492: 486: 482: 479: 478: 474: 468: 464: 461: 460: 456: 454: 453: 448: 447: 443: 441: 440:Melting point 438: 437: 430: 428: 425: 424: 400: 397: 393: 392: 387: 378: 377: 374: 367: 353: 352: 349: 342: 334: 330: 329:DTXSID7040526 326: 325: 323: 313: 309: 308: 301: 297: 296: 294: 292: 289: 288: 281: 277: 276: 274: 268: 264: 263: 259: 255: 253: 250: 249: 242: 238: 237: 235: 233: 230: 229: 222: 218: 217: 215: 213: 210: 209: 202: 198: 197: 195: 193: 190: 189: 182: 178: 177: 175: 173: 170: 169: 165: 162: 158: 157: 150: 146: 145: 143: 139: 134: 133: 126: 122: 121: 119: 116: 112: 111: 106: 98: 92: 88: 84: 78: 74: 65: 61: 56: 52: 47: 43: 38: 30: 19: 5091:Excitotoxins 5061:Pyrrolidines 5020: 5019: 4853:-Cycloserine 4707: 4603:Acid red 114 4579:4-Methylene- 4543: 4505: 4469: 4459: 4432: 4323: 4322: 4280:Antagonists: 4279: 4269: 4249: 4220: 4179:Antagonists: 4178: 4150: 4097:Antagonists: 4096: 4078: 4025:Antagonists: 4024: 4009: 3974: 3927: 3886:Antagonists: 3885: 3879:Talaglumetad 3825: 3791: 3745:Antagonists: 3744: 3734: 3731:Talaglumetad 3667: 3604:Dipraglurant 3599:Basimglurant 3590: 3544:Antagonists: 3543: 3533: 3481: 3423:Antagonists: 3422: 3367: 3287: 3280: 3271: 3270: 3254: 3251: 3123: 3030:Cyclopropane 3011: 2994: 2972: 2908: 2860:Propoxyphene 2830:Orphenadrine 2735:Ketobemidone 2700:Eticyclidine 2635:Coronaridine 2620:ARL-15896-AR 2536: 2504: 2416:-Cycloserine 2398:Carisoprodol 2354: 2242: 2240:Antagonists: 2239: 2172: 2167: 2150: 2078:-Cycloserine 2019: 1958: 1955: 1899:Barbiturates 1895: 1872:Selurampanel 1827:Dasolampanel 1814:Antagonists: 1813: 1783: 1759: 1716: 1713: 1687: 1624:Cyclopropane 1610:Barbiturates 1606: 1578:Selurampanel 1528:Dasolampanel 1500:Antagonists: 1499: 1483:Pramiracetam 1359: 1307: 1304: 1202: 1196: 1184:. Retrieved 1172: 1168: 1158: 1123: 1119: 1109: 1092: 1082: 1065: 1059: 1040: 1033: 1000: 996: 990: 965: 961: 955: 920: 916: 906: 873: 869: 863: 838: 830: 805: 797: 758:modeling of 752:modeling of 744:neuroscience 738:Applications 719: 715: 706:anthelmintic 695: 689: 684: 666: 664: 659: 655: 651: 649: 646:Biosynthesis 627: 615: 601:, a type of 562: 558: 557: 484: 466: 451: 108:Identifiers 100:Other names 90: 86: 82: 63: 59: 35:Kainic acid 5066:Convulsants 4891:Chloroquine 4720:Valinomycin 4715:Trypan blue 4697:Rose bengal 4682:NPPB (N144) 4556:WAY-213,613 4460:Kainic acid 4422:Amphetamine 4400:Transporter 4006:VU-0155,041 3931:Decoglurant 3795:Decoglurant 3629:Raseglurant 3577:Remeglurant 3562:Mavoglurant 3426:BAY 36-7620 3220:Pentamidine 3205:Minocycline 3185:Hodgkinsine 3155:Dexanabinol 3085:Sevoflurane 2939:Isoxsuprine 2934:Haloperidol 2914:Besonprodil 2875:Rimantadine 2825:Norketamine 2820:Noribogaine 2795:Milnacipran 2760:Levorphanol 2710:Gacyclidine 2680:Dizocilpine 2675:Diphenidine 2665:Dextrorphan 2585:Alaproclate 2528:Huperzine A 2481:Meprobamate 2441:Harkoseride 2336:Perzinfotel 2213:Plazinemdor 1760:Kainic acid 1745:Domoic acid 1691:Minocycline 1679:Sevoflurane 1356:Willardiine 1331:Domoic acid 1201:Barrow PA. 1186:22 February 1064:Barrow PA. 779:Domoic acid 660:Escherichia 622:excitotoxic 589:receptors, 559:Kainic acid 510:Monoclinic 389:Properties 258:Kainic+acid 201:ChEMBL27527 181:CHEBI:31746 5050:Categories 4954:JFD01307SC 4687:Ponceau SS 4662:Furosemide 4657:Evans blue 4623:Bumetamide 4583:-glutamate 4392:modulators 4385:metabolism 4273:AZ12216052 4013:Foliglurax 4001:VU-001,171 3914:LY-341,495 3909:LY-307,452 3864:LY-487,379 3854:LY-379,268 3773:LY-341,495 3768:LY-307,452 3716:LY-566,332 3711:LY-487,379 3701:LY-379,268 3557:LY-344,545 3537:LSN2463359 3446:LY-456,236 3441:LY-367,385 3335:modulators 3258:AGN-241751 3230:Piretanide 3180:Furosemide 3165:Flupirtine 3142:Conantokin 3137:Caroverine 3132:Bumetanide 3065:Isoflurane 3035:Desflurane 3025:Chloroform 2964:Safaprodil 2959:Ro 25-6981 2900:Tiletamine 2885:Sabeluzole 2865:Remacemide 2810:Neramexane 2780:Methorphan 2765:Loperamide 2740:Lanicemine 2725:Indantadol 2690:Esketamine 2685:Ephenidine 2645:Dexoxadrol 2610:Arketamine 2595:Amantadine 2555:3-MeO-PCMo 2533:Putrescine 2476:MDL-105519 2451:Kynurenine 2431:Gavestinel 2346:SDZ-220581 2306:MDL-100453 2189:prasterone 2159:Spermidine 2132:Milacemide 2037:ACC (ACPC) 1923:Evans blue 1887:Topiramate 1877:Tezampanel 1807:Isoflurane 1684:Talampanel 1669:Perampanel 1664:Isoflurane 1649:GYKI-53655 1644:GYKI-52466 1639:Evans blue 1603:Zonampanel 1593:Topiramate 1583:Tezampanel 1558:Kynurenine 1518:Caroverine 1513:Becampanel 1463:Oxiracetam 1363:Aniracetam 1284:modulators 1241:modulators 790:References 681:Occurrence 498:Structure 427:Molar mass 300:SIV03811UC 212:ChemSpider 136:3D model ( 115:CAS Number 55:IUPAC name 5021:See also: 4886:Bithionol 4841:β-Chloro- 4677:Nigericin 4389:transport 4382:Glutamate 4324:See also: 4258:Glutamate 4250:Agonists: 4172:LSP2-9166 4159:Glutamate 4151:Agonists: 4082:Glutamate 4079:Agonists: 3991:LSP2-9166 3978:Glutamate 3975:Agonists: 3950:Group III 3936:RO4491533 3844:Glutamate 3839:Eglumegad 3826:Agonists: 3800:RO4491533 3691:Glutamate 3686:Eglumegad 3668:Agonists: 3515:Glutamate 3490:ADX-47273 3482:Agonists: 3406:Ro67-7476 3401:Ro67-4853 3396:Ro01-6128 3381:Glutamate 3368:Agonists: 3272:See also: 3252:Unsorted: 3195:MDL-27266 3175:FR-115427 3170:FPL-12495 3127:ARR-15896 3055:Halothane 3045:Enflurane 3003:Magnesium 2954:Ro 8-4304 2929:Eliprodil 2840:PD-137889 2800:Morphanol 2775:Methadone 2770:Memantine 2720:Ibogamine 2695:Etoxadrol 2625:ARL-16247 2615:ARL-12495 2600:Aptiganel 2565:4-MeO-PCP 2560:3-MeO-PCP 2550:3-MeO-PCE 2513:Co 101676 2486:MRZ 2/576 2436:GV-196771 2426:Felbamate 2403:CGP-39653 2383:ACEA-1328 2378:ACEA-1011 2321:NPC-17742 2316:NPC-12626 2301:LY-274614 2296:LY-235959 2291:LY-233053 2276:CGS-19755 2271:CGP-40116 2266:CGP-39653 2261:CGP-39551 2256:CGP-37849 2246:AP5 (APV) 2147:Sarcosine 2023:β-Fluoro- 1972:Glutamate 1967:Aspartate 1956:Agonists: 1913:Enflurane 1857:LY-382884 1817:ACEA-1011 1802:Halothane 1797:Enflurane 1792:Diazoxide 1765:LY-339434 1750:Glutamate 1714:Agonists: 1659:Irampanel 1654:Halothane 1629:Enflurane 1503:ACEA-1011 1478:Piracetam 1458:ORG-26576 1453:Nooglutyl 1443:LY-503430 1438:LY-451646 1433:LY-404187 1428:LY-395153 1423:LY-392098 1408:Diazoxide 1336:Glutamate 1305:Agonists: 898:254384979 746:research 575:glutamate 4845:-alanine 4551:UCPH-101 4538:Theanine 4533:TFB-TBOA 4523:SYM-2081 4508:-2,4-PDC 4308:UBP-1112 4224:ADX71743 4212:UBP-1112 4125:UBP-1112 4053:UBP-1112 3924:MGS-0039 3869:MGS-0028 3783:MGS-0039 3721:MGS-0028 3643:Group II 3587:SIB-1893 3582:SIB-1757 3572:NPS-2390 3456:NPS-2390 3416:Theanine 3200:Metaphit 3110:Urethane 2998:Hydrogen 2995:Cations: 2905:Tramadol 2730:Ketamine 2715:Ibogaine 2630:Budipine 2545:3-HO-PCP 2471:LU-73068 2461:L-701324 2456:L-689560 2363:5,7-DCKA 2351:Selfotel 2233:SAGE-718 2228:SAGE-301 2223:SAGE-201 2164:Spermine 2154:Neomycin 2119:-Alanine 2111:L-687414 2070:-Alanine 2027:-alanine 2016:Theanine 1882:Theanine 1780:SYM-2081 1588:Theanine 1211:53634796 1150:24760837 1101:22787646 1074:53634796 1025:42116946 1017:20833150 1003:: 8–16. 947:30995339 890:31197744 768:See also 754:epilepsy 687:seaweeds 481:Basicity 125:487-79-6 70:-proline 3614:GRN-529 3609:Fenobam 3594:AZD9272 3530:VU-1545 3431:CPCCOEt 3343:Group I 3244:saffron 3090:Toluene 3080:Octanol 3060:Hexanol 3015:Benzene 2991:TCN-213 2986:TCN-201 2981:MPX-007 2976:MPX-004 2570:8A-PDHQ 2508:Arcaine 2501:ZD-9379 2198:sulfate 2127:-Serine 2101:Glycine 2086:-Serine 2001:Proline 1928:NS-3763 1901:(e.g., 1892:UBP-302 1770:Proline 1612:(e.g., 1488:S-18986 1418:IDRA-21 1403:CX-1942 1398:CX-1739 1346:Proline 1141:3996208 982:9586226 938:6574125 635:lesions 571:agonist 567:seaweed 563:kainate 540:what is 538: ( 493:11.966 463:Acidity 432:213.233 267:PubChem 29:Kainite 18:Kainate 4906:GW5074 4766:CB-839 4739:Enzyme 4567:vGluTs 4217:XAP044 4154:AMN082 3834:DCG-IV 3829:CBiPES 3788:PCCG-4 3681:DCG-IV 3676:CBiPES 3120:Xylene 3020:Butane 2393:AV-101 2106:HA-966 1393:CX-717 1383:CX-614 1378:CX-546 1373:CX-516 1209:  1148:  1138:  1099:  1072:  1047:  1023:  1015:  980:  945:  935:  896:  888:  851:  818:  535:verify 532:  475:2.031 457:0.635 373:SMILES 241:C12819 192:ChEMBL 166:86660 49:Names 4761:BPTES 4710:-ACDP 4708:trans 4598:7-CKA 4544:threo 4506:trans 4470:threo 4468:-(-)- 4455:HIP-B 4450:HIP-A 4435:-ACBD 4410:EAATs 4235:mGluR 4192:MMPIP 4136:mGluR 4064:mGluR 3996:PHCCC 3960:mGluR 3904:HYDIA 3894:CECXG 3889:APICA 3811:mGluR 3763:HYDIA 3753:CECXG 3748:APICA 3653:mGluR 3552:DMeOB 3495:CDPPB 3467:mGluR 3411:VU-71 3353:mGluR 3115:Xenon 2575:18-MC 2540:2-MDP 2368:7-CKA 2331:PEAQX 2057:B6B21 2047:AK-51 1981:-HCA) 1944:NMDAR 1867:NS102 1598:YM90K 1293:AMPAR 1021:S2CID 894:S2CID 731:GluK2 702:Japan 561:, or 348:InChI 280:10255 172:ChEBI 138:JSmol 4992:AAOA 4896:EGCG 4881:AAOA 4799:AAOA 4702:SITS 4638:DIDS 4528:TBOA 4513:MPDC 4480:-αAA 4440:DHKA 4387:and 4303:MTPG 4298:MSOP 4293:MPPG 4288:MAP4 4283:CPPG 4266:-AP4 4253:DCPG 4207:MTPG 4202:MSOP 4197:MPPG 4187:MAP4 4182:CPPG 4167:-AP4 4120:MTPG 4115:MSOP 4110:MPPG 4105:MAP4 4100:CPPG 4090:-AP4 4048:MTPG 4043:MSOP 4038:MPPG 4033:MAP4 4028:CPPG 4018:MPEP 3986:-AP4 3919:MCPG 3899:EGLU 3778:MCPG 3758:EGLU 3671:BINA 3624:MTEP 3619:MPEP 3567:MCPG 3547:CTEP 3510:DHPG 3500:CHPG 3485:ACPD 3451:MCPG 3376:DHPG 3371:ACPD 3210:MPEP 3150:-αAA 3008:Zinc 2835:PCPr 2805:NEFA 2491:PNQX 2421:DNQX 2408:CNQX 2341:PPDA 2326:PBPD 2196:DHEA 2181:DHEA 2091:DHPG 2042:ACPD 2032:ACBD 1996:NMDA 1962:AMAA 1862:NBQX 1837:GAMS 1832:DNQX 1822:CNQX 1740:ATPA 1735:AMPA 1573:PNQX 1568:NBQX 1543:GAMS 1533:DNQX 1523:CNQX 1508:ATPO 1468:PEPA 1326:BOAA 1321:AMPA 1207:OCLC 1188:2021 1146:PMID 1097:PMID 1070:OCLC 1045:ISBN 1013:PMID 1001:1360 978:PMID 943:PMID 886:PMID 849:ISBN 816:ISBN 694:and 591:AMPA 587:NMDA 450:log 291:UNII 252:MeSH 232:KEGG 221:9837 4975:GAD 4901:GTP 4869:GDH 4829:ALT 4804:AMB 4782:AST 4771:DON 4749:GAH 4433:cis 3505:DFB 2373:ACC 2281:CPP 2251:AP7 2062:CCG 1702:KAR 1177:doi 1136:PMC 1128:doi 1005:doi 970:doi 933:PMC 925:doi 878:doi 845:152 812:121 656:kab 317:EPA 270:CID 5052:: 5034:• 5030:• 5026:• 4937:GS 4811:DL 4809:β- 4333:• 4329:• 4268:; 4219:; 4008:; 3926:; 3790:; 3733:; 3589:; 3532:; 3122:; 3010:; 2993:; 2971:; 2907:; 2535:; 2503:; 2353:; 2171:24 2166:; 2149:; 2018:; 1905:, 1894:; 1782:; 1686:; 1616:, 1605:; 1358:; 1205:. 1173:78 1171:. 1167:. 1144:. 1134:. 1124:34 1122:. 1118:. 1068:. 1019:. 1011:. 999:. 976:. 966:15 964:. 941:. 931:. 921:58 919:. 915:. 892:. 884:. 874:39 872:. 847:. 814:. 708:. 585:: 490:) 483:(p 472:) 465:(p 411:15 405:10 89:,4 85:,3 81:(2 62:,4 58:(3 4998:L 4851:L 4843:L 4650:L 4581:L 4504:- 4502:L 4494:L 4486:L 4478:L 4466:L 4374:e 4367:t 4360:v 4264:L 4237:8 4165:L 4138:7 4088:L 4066:6 3984:L 3962:4 3813:3 3655:2 3469:5 3355:1 3324:e 3317:t 3310:v 3246:) 3242:( 3148:D 2414:D 2204:) 2200:( 2191:) 2187:( 2173:S 2125:L 2117:L 2084:D 2076:D 2068:D 2025:D 1979:L 1909:) 1620:) 1273:e 1266:t 1259:v 1213:. 1190:. 1179:: 1152:. 1130:: 1103:. 1076:. 1053:. 1027:. 1007:: 984:. 972:: 949:. 927:: 900:. 880:: 857:. 824:. 667:N 530:N 488:b 485:K 470:a 467:K 452:P 420:4 417:O 414:N 408:H 402:C 319:) 315:( 140:) 91:S 87:S 83:S 68:L 64:S 60:S 31:. 20:)

Index

Kainate
Kainite
Stereo, skeletal formula of kainic acid
IUPAC name
Systematic IUPAC name
CAS Number
487-79-6
JSmol
Interactive image
Beilstein Reference
ChEBI
CHEBI:31746
ChEMBL
ChEMBL27527
ChemSpider
9837
KEGG
C12819
MeSH
Kainic+acid
PubChem
10255
UNII
SIV03811UC
CompTox Dashboard
DTXSID7040526
Edit this at Wikidata
InChI
SMILES
Chemical formula

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