335:, once the doyen of medical history, the often violent and invasive psychiatric interventions developed during the 1930s and 1940s are indicative of both the well-intentioned desire of psychiatrists to find some medical means of alleviating the suffering of the vast number of patients then in psychiatric hospitals and also the relative lack of social power of those same patients to resist the increasingly radical and even reckless interventions of asylum doctors. Many doctors, patients and family members of the period believed that despite potentially catastrophic consequences, the results of lobotomy were seemingly positive in many instances or, were at least deemed as such when measured next to the apparent alternative of long-term institutionalisation. Lobotomy has always been controversial, but for a period of the medical mainstream, it was even feted and regarded as a legitimate last-resort remedy for categories of patients who were otherwise regarded as hopeless. Today, lobotomy has become a disparaged procedure, a byword for medical barbarism and an exemplary instance of the medical trampling of
327:(1938), served to galvanize a profession which had been both therapeutically moribund and systemically demoralized. Unlike other medical disciplines (e.g., Cardiology, Dermatology, Orthopedics, etc.) which applied surgical and pharmacological treatments that were both apparent and measurable regarding their efficacy, psychiatry had often struggled with quantification. These novel remedial methodologies, however, meant that (at the time) modern psychiatric treatments were no longer relegated to the metaphysical or abstract, and this increased the popularity of the field among clinicians and prospective patients alike. Suddenly, conditions like insanity, psychosis, and others felt less like incurable afflictions, and more like surmountable diagnoses - emboldening psychiatrists to attempt new procedures. Additionally, the relative (and quantitative) success of the shock therapies, despite the considerable risks they posed to patients, also helped to inspire doctors in the field to pioneer ever more drastic forms of medical interventions up to, and including, lobotomies.
529:, named Becky and Lucy who had had frontal lobectomies and subsequent changes in behaviour and intellectual function. According to Fulton's account of the congress, they explained that before surgery, both animals, and especially Becky, the more emotional of the two, exhibited "frustrational behaviour" – that is, have tantrums that could include rolling on the floor and defecating – if, because of their poor performance in a set of experimental tasks, they were not rewarded. Following the surgical removal of their frontal lobes, the behaviour of both primates changed markedly and Becky was pacified to such a degree that Jacobsen apparently stated it was as if she had joined a "happiness cult". During the question and answer section of the paper, Moniz, it is alleged, "startled" Fulton by inquiring if this procedure might be extended to human subjects suffering from mental illness. Fulton stated that he replied that while possible in theory it was surely "too formidable" an intervention for use on humans.
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Médico-Psychologique on the results of the second cohort of patients leucotomised by Lima. Sobral Cid, who had supplied Moniz with the first set of patients for leucotomy from his own hospital in Lisbon, attended the meeting and denounced the technique, declaring that the patients who had been returned to his care post-operatively were "diminished" and had experienced a "degradation of personality". He also claimed that the changes Moniz observed in patients were more properly attributed to shock and brain trauma, and he derided the theoretical architecture that Moniz had constructed to support the new procedure as "cerebral mythology." At the same meeting the
Parisian psychiatrist, Paul Courbon, stated he could not endorse a surgical technique that was solely supported by theoretical considerations rather than clinical observations. He also opined that the mutilation of an organ could not improve its function and that such cerebral wounds as were occasioned by leucotomy risked the later development of
934:. Freeman had first encountered Moniz at the London-hosted Second International Congress of Neurology in 1935, where he had presented a poster exhibit of the Portuguese neurologist's work on cerebral angiography. Fortuitously occupying a booth next to Moniz, Freeman, delighted by their chance meeting, formed a highly favourable impression of Moniz, later remarking upon his "sheer genius". According to Freeman, if they had not met in person, it is highly unlikely that he would have ventured into the domain of frontal lobe psychosurgery. Freeman's interest in psychiatry was the natural outgrowth of his appointment in 1924 as the medical director of the Research Laboratories of the Government Hospital for the Insane in Washington, known colloquially as St Elizabeth's. Freeman, who favoured an organic model of mental illness causation, spent the next several years exhaustively, yet ultimately fruitlessly, investigating a
614:, a French neuropsychiatrist, who commenced the session by reviewing the state of research on the frontal lobes, and concluded that "altering the frontal lobes profoundly modifies the personality of subjects". This parallel symposium contained numerous papers by neurologists, neurosurgeons and psychologists; amongst these was one by Brickner, which impressed Moniz greatly, that again detailed the case of "Patient A". Fulton and Jacobsen's paper, presented in another session of the conference on experimental physiology, was notable in linking animal and human studies on the function of the frontal lobes. Thus, at the time of the 1935 Congress, Moniz had available to him an increasing body of research on the role of the frontal lobes that extended well beyond the observations of Fulton and Jacobsen.
634:, the French physician Maurice Ducosté reported in 1932 that he had injected 5 ml of malarial blood directly into the frontal lobes of over 100 paretic patients through holes drilled into the skull. He claimed that the injected paretics showed signs of "uncontestable mental and physical amelioration" and that the results for psychotic patients undergoing the procedure was also "encouraging". The experimental injection of fever-inducing malarial blood into the frontal lobes was also replicated during the 1930s in the work of Ettore Mariotti and M. Sciutti in Italy and Ferdière Coulloudon in France. In Switzerland, almost simultaneously with the commencement of Moniz's leucotomy programme, the neurosurgeon François Ody had removed the entire right frontal lobe of a
946:. Praising the text as one whose "importance can scarcely be overestimated", he summarised Moniz's rationale for the procedure as based on the fact that while no physical abnormality of cerebral cell bodies was observable in the mentally ill, their cellular interconnections may harbour a "fixation of certain patterns of relationship among various groups of cells" and that this resulted in obsessions, delusions and mental morbidity. While recognising that Moniz's thesis was inadequate, for Freeman it had the advantage of circumventing the search for diseased brain tissue in the mentally ill by instead suggesting that the problem was a functional one of the brain's internal wiring where relief might be obtained by severing problematic mental circuits.
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patients in novels, plays, and films further diminished public opinion, and the development of antipsychotic medications led to a rapid decline in lobotomy’s popularity and
Freeman’s reputation. Others could leave the hospital or become more manageable within the hospital. A precarious amount of people managed to return to responsible work, while at the other extreme, people were left with severe and disabling impairments. Most people fell into an intermediate group, left with some improvement of their symptoms but also with emotional and intellectual deficits to which they made a better or worse adjustment. On average, there was a mortality rate of approximately 5% during the 1940s.
730:, and create what Moniz termed a "frontal barrier". After the first operation was complete, Moniz considered it a success and, observing that the patient's depression had been relieved, he declared her "cured" although she was never, in fact, discharged from the mental hospital. Moniz and Lima persisted with this method of injecting alcohol into the frontal lobes for the next seven patients but, after having to inject some patients on numerous occasions to elicit what they considered a favourable result, they modified the means by which they would section the frontal lobes. For the ninth patient they introduced a surgical instrument called a
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lobotomized 2.5 times as many people per capita as hospitals in the US. According to another estimate, Sweden lobotomized at least 4,500 people between 1944 and 1966, mainly women. This figure includes young children. And in Norway, there were 2,005 known lobotomies. In
Denmark, there were 4,500 known lobotomies. In Japan, the majority of lobotomies were performed on children with behaviour problems. The Soviet Union banned the practice in 1950 on moral grounds. In Germany, it was performed only a few times. By the late 1970s, the practice of lobotomy had generally ceased, although it continued as late as the 1980s in France.
767:. Their most prominent symptoms were anxiety and agitation. The duration of their illness before the procedure varied from as little as four weeks to as much as 22 years, although all but four had been ill for at least one year. Patients were normally operated on the day they arrived at Moniz's clinic and returned within ten days to the Miguel Bombarda Mental Hospital. A perfunctory post-operative follow-up assessment took place anywhere from one to ten weeks following surgery. Complications were observed in each of the leucotomy patients and included: "increased temperature, vomiting,
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of such lobotomized patients exhibited reduced tension or agitation, but many also showed other effects, such as apathy, passivity, lack of initiative, poor ability to concentrate, and a generally decreased depth and intensity of their emotional response to life. Some died as a result of the procedure. However, those effects were not widely reported in the 1940s, and at that time the long-term effects were largely unknown. Because the procedure met with seemingly widespread success, Moniz was awarded the 1949 Nobel Prize for
Physiology or Medicine (along with Swiss physiologist
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overwhelming demand for the operation. In 1945 Freeman streamlined the procedure, replacing it with transorbital lobotomy, in which a picklike instrument was forced through the back of the eye sockets to pierce the thin bone that separates the eye sockets from the frontal lobes. The pick’s point was then inserted into the frontal lobe and used to sever connections in the brain (presumably between the prefrontal cortex and thalamus). In 1946 Freeman performed this procedure for the first time on a patient, who was subdued prior to the operation with electroshock treatment.
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of the patient was changed in some way in the hope of rendering him more amenable to the social pressures under which he is supposed to exist." He described one 29-year-old woman as being, following lobotomy, a "smiling, lazy and satisfactory patient with the personality of an oyster" who could not remember
Freeman's name and endlessly poured coffee from an empty pot. When her parents had difficulty dealing with her behavior, Freeman advised a system of rewards (ice cream) and punishment (smacks).
707:, Moniz initiated the first of a series of operations on the brains of people with mental illnesses. The initial patients selected for the operation were provided by the medical director of Lisbon's Miguel Bombarda Mental Hospital, José de Matos Sobral Cid. As Moniz lacked training in neurosurgery and his hands were impaired by gout, the procedure was performed under general anaesthetic by Pedro Almeida Lima, who had previously assisted Moniz with his research on
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252:, and it was recognized that this was accomplished at the expense of a person's personality and intellect. British psychiatrist Maurice Partridge, who conducted a follow-up study of 300 patients, said the treatment achieved its effects by "reducing the complexity of psychic life". Following the operation, spontaneity, responsiveness, self-awareness, and self-control were reduced. The activity was replaced by inertia, and people were mostly left
473:. He had abandoned these attempts because of unsatisfactory results and this experience probably inspired the invective that was directed at Burckhardt in the 1912 article. By 1937, Puusepp, despite his earlier criticism of Burckhardt, was increasingly persuaded that psychosurgery could be a valid medical intervention for the mentally disturbed. In the late 1930s, he worked closely with the neurosurgical team of the Racconigi Hospital near
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performed in the United States. However, because of the fervent promotion of the technique by
Freeman and Watts, those numbers increased sharply toward the end of the decade. In 1949, the peak year for lobotomies in the US, 5,074 procedures were undertaken, and by 1951 over 18,608 individuals had been lobotomized in the US. An estimated 40% of Freeman's patients were gay men, lobotomized to change their sexual orientation.
280:
791:, and abnormal sensations of hunger". Moniz asserted that these effects were transitory and, according to his published assessment, the outcome for these first twenty patients was that 35%, or seven cases, improved significantly, another 35% were somewhat improved and the remaining 30% (six cases) were unchanged. There were no deaths and he did not consider that any patients had deteriorated following leucotomy.
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earlier unpublished account he wrote of the congress. In this previous narrative he mentioned an incidental, private exchange with Moniz, but it is likely that the official version of their public conversation he promulgated is without foundation. In fact, Moniz stated that he had conceived of the operation some time before his journey to London in 1935, having told in confidence his junior colleague, the young
38:
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in the synaptic complex which regulates the functioning of consciousness, stimulating it and keeping it in constant activity ... all these considerations led me to the following conclusion: it is necessary to alter these synaptic adjustments and change the paths chosen by the impulses in their constant passage so as to modify the corresponding ideas and force thoughts along different paths ...'
1075:, created the National Committee for the Protection of Human Subjects of Biomedical and Behavioral Research to investigate allegations that psychosurgery – including lobotomy techniques – was used to control minorities and restrain individual rights. The committee concluded that some extremely limited and properly performed psychosurgery could have positive effects.
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leucotomize schizophrenics" and that lobotomy was "still too imperfect to enable us, with its aid, to venture on a general offensive against chronic cases of mental disorder", stating further that "Psychosurgery has as yet failed to discover its precise indications and contraindications and the methods must unfortunately still be regarded as rather crude and hazardous in many respects." In 1948
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1189: – to render them "morally sane". In the play, a wealthy matriarch offers the local mental hospital a substantial donation if the hospital will give her niece a lobotomy, which she hopes will stop the niece's shocking revelations about her son. Warned that a lobotomy might not stop her niece's "babbling", she responds, "That may be, maybe not, but after the operation, who would
846: – the Racconigi Hospital – where he instructed his Italian neuropsychiatric colleagues on leucotomy and also oversaw several operations. Leucotomy was featured at two Italian psychiatric conferences in 1937 and over the next two years a score of medical articles on Moniz's psychosurgery was published by Italian clinicians based in medical institutions located in
586:, which designated a neurological condition characterised by a certain hilarity and childishness in those with the condition. The picture of frontal lobe function that emerged from these studies was complicated by the observation that neurological deficits attendant on damage to a single lobe might be compensated for if the opposite lobe remained intact. In 1922, the Italian neurologist
452:, published a paper reviewing a range of surgical interventions that had been performed on the mentally ill. While generally treating these endeavours favorably, in their consideration of psychosurgery they reserved unremitting scorn for Burckhardt's surgical experiments of 1888 and opined that it was extraordinary that a trained medical doctor could undertake such an unsound procedure.
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602:, had no apparent decrease in intellectual function and seemed, at least to the casual observer, perfectly normal. Brickner concluded from this evidence that "the frontal lobes are not 'centers' for the intellect". These clinical results were replicated in a similar operation undertaken in 1934 by the neurosurgeon
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371:. Burckhardt's decision to operate was informed by three pervasive views on the nature of mental illness and its relationship to the brain. First, the belief that mental illness was organic in nature, and reflected an underlying brain pathology; next, that the nervous system was organized according to an
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diabolical. Just observing this thing was horrible, gruesome." When Dully asked Frank
Freeman, then a 79-year-old security guard, whether he was proud of his father, he replied: "Oh yes, yes, yeah. He was terrific. He was really quite a remarkable pioneer lobotomist. I wish he could have gotten further."
1552:
Rodney Dully, whose son Howard Dully had had a transorbital lobotomy performed on him by Walter
Freeman when he was twelve years old, stated in an interview with his son that: "I only met him I think the one time. He described how accurate it was and that he had practised the cutting on, literally,
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A 1937 report detailed that in the United States there were then 477 psychiatric institutions with a total population of approximately 451,672 patients, almost half of whom had been resident for a period of five years or more. The report also observed that psychiatric patients occupied 55 per cent of
1210:, lobotomy is described as "frontal-lobe castration", a form of punishment and control after which "There's nothin' in the face. Just like one of those store dummies." In one patient, "You can see by his eyes how they burned him out over there; his eyes are all smoked up and gray and deserted inside."
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Throughout the remainder of the 1930s the number of leucotomies performed in most countries where the technique was adopted remained quite low. In
Britain, which was later a major centre for leucotomy, only six operations had been undertaken before 1942. Generally, medical practitioners who attempted
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In the present state of affairs if some are critical about lack of caution in therapy, it is, on the other hand, deplorable and inexcusable to remain apathetic, with folded hands, content with learned lucubrations upon symptomatologic minutiae or upon psychopathic curiosities, or even worse, not even
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The frontal lobes had been the object of scientific inquiry and speculation since the late 19th century. Fulton's contribution, while it may have functioned as source of intellectual support, is of itself unnecessary and inadequate as an explanation of Moniz's resolution to operate on this section of
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The consequences of the operation have been described as "mixed". However, many lobotomy patients suffered devastating postoperative complications, including intracranial hemorrhage, epilepsy, alterations in affect and personality, brain abscess, dementia, and death. Ominous portrayals of lobotomized
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Frank
Freeman, Walter Freeman's son, stated in an interview with Howard Dully that: "He had several ice-picks that just cluttered the back of the kitchen drawer. The first ice-pick came right out of our drawer. A humble ice-pick to go right into the frontal lobes. It was, from a cosmetic standpoint,
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Moniz wrote in 1948: 'sufferers from melancholia, for instance, are distressed by fixed and obsessive ideas ... and live in a permanent state of anxiety caused by a fixed idea which predominates over all their lives ... in contrast to automatic actions, these morbid ideas are deeply rooted
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The Freeman–Watts prefrontal lobotomy still required drilling holes in the skull, so surgery had to be performed in an operating room by trained neurosurgeons. Walter Freeman believed this surgery would be unavailable to those he saw as needing it most: patients in state mental hospitals that had no
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For Moniz, "to cure these patients", it was necessary to "destroy the more or less fixed arrangements of cellular connections that exist in the brain, and particularly those which are related to the frontal lobes", thus removing their fixed pathological brain circuits. Moniz believed the brain would
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published a detailed report on the results of bilateral lobectomies in animals that supported the contention that the frontal lobes were both integral to intellectual function and that their removal led to the disintegration of the subject's personality. This work, while influential, was not without
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in humans and led to more precise experimental neurosurgery in animal studies. Cases were reported where mental symptoms were alleviated following the surgical removal of diseased or damaged brain tissue. The accumulation of medical case studies on behavioural changes following damage to the frontal
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that "seldom in the history of medicine has a laboratory observation been so quickly and dramatically translated into a therapeutic procedure". Fulton's report, penned ten years after the events described, is, however, without corroboration in the historical record and bears little resemblance to an
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coined the term "surgically induced childhood" and used it constantly to refer to the results of lobotomy. The operation left people with an "infantile personality"; a period of maturation would then, according to Freeman, lead to recovery. In an unpublished memoir, he described how the "personality
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remarked: "The history of prefrontal lobotomy has been brief and stormy. Its course has been dotted with both violent opposition and with slavish, unquestioning acceptance." Beginning in 1947 Swedish psychiatrist Snorre Wohlfahrt evaluated early trials, reporting that it is "distinctly hazardous to
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Watts did not favor the transorbital method, and this difference of opinion contributed to the end of their partnership. Watts resisted the technique itself, Freeman's lack of sterile technique when performing it, and the idea of performing the procedure in an outpatient setting.Watts recalled that
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The transorbital lobotomy procedure, which Freeman performed very quickly, sometimes in less than 10 minutes, was used on many patients with relatively minor mental disorders that Freeman believed did not warrant traditional lobotomy surgery, in which the skull itself was opened. A large proportion
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basis for insanity. Chancing upon a preliminary communication by Moniz on leucotomy in the spring of 1936, Freeman initiated a correspondence in May of that year. Writing that he had been considering psychiatric brain surgery previously, he informed Moniz that, "having your authority I expect to go
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mental troubles must have ... a relation with the formation of cellulo-connective groupings, which become more or less fixed. The cellular bodies may remain altogether normal, their cylinders will not have any anatomical alterations; but their multiple liaisons, very variable in normal people,
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and, most especially, the frontal lobes, were responsible for more complex cognitive functions. However, this theoretical formulation found little laboratory support, as 19th-century experimentation found no significant change in animal behaviour following surgical removal or electrical stimulation
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in regions of the brain identified as association centers, a transformation in behaviour might ensue. According to his model, those mentally ill might experience "excitations abnormal in quality, quantity and intensity" in the sensory regions of the brain and this abnormal stimulation would then be
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In the early 20th century, the number of patients residing in mental hospitals increased significantly while little in the way of effective medical treatment was available. Lobotomy was one of a series of radical and invasive physical therapies developed in Europe at this time that signaled a break
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Puusepp admitted to his 1910 experimentation with psychosurgery in a 1937 publication. At that point he had completed a series of 14 leucotomies to relieve aggressive symptoms in patients. Convinced that the results had been positive in these cases, he felt that further research into psychosurgery
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Moniz began his experiments with leucotomy just three months after the congress had reinforced the apparent cause and effect relationship between the Fulton and Jacobsen presentation and the Portuguese neurologist's resolve to operate on the frontal lobes. As the author of this account Fulton, who
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The source of inspiration for Moniz's decision to hazard psychosurgery has been clouded by contradictory statements made on the subject by Moniz and others both contemporaneously and retrospectively. The traditional narrative addresses the question of why Moniz targeted the frontal lobes by way of
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Freeman performed the first transorbital lobotomy on a live patient in 1946. Its simplicity suggested the possibility of carrying it out in mental hospitals lacking the surgical facilities required for the earlier, more complex procedure. (Freeman suggested that, where conventional anesthesia was
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By the conclusion of this first run of leucotomies in February 1936, Moniz and Lima had operated on twenty patients with an average period of one week between each procedure; Moniz published his findings with great haste in March of the same year. The patients were aged between 27 and 62 years of
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that was 11 centimetres (4.3 in) in length and 2 centimetres (0.79 in) in diameter. It had a retractable wire loop at one end that, when rotated, produced a 1 centimetre (0.39 in) diameter circular lesion in the white matter of the frontal lobe. Typically, six lesions were cut into
610:. By the mid-1930s, interest in the function of the frontal lobes reached a high-water mark. This was reflected in the 1935 neurological congress in London, which hosted as part of its deliberations, "a remarkable symposium ... on the functions of the frontal lobes". The panel was chaired by
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It is assumed that the transection of white substance of the frontal lobes impairs their connection with the thalamus and eliminates the possibility to receive from it stimuli which lead to irritation and on the whole derange mental functions. This explanation is mechanistic and goes back to the
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In the United States, approximately 40,000 people were lobotomized and in England, 17,000 lobotomies were performed. According to one estimate, in the three Nordic countries of Denmark, Norway, and Sweden, a combined figure of approximately 9,300 lobotomies were performed. Scandinavian hospitals
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Lobotomies were performed on a wide scale during the 1940s; Freeman himself performed or supervised more than 3,500 lobotomies by the late 1960s. Freeman performed his first transorbital lobotomy on Ellen Ionesco, a woman who suffered from bouts of manic depression and suicidal ideation. Freeman
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The use of lobotomy in the United States was resisted and criticized heavily by American neurosurgeons. However, because Freeman managed to promote the success of the surgery through the media, lobotomy became touted as a miracle procedure, capturing the attention of the public and leading to an
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Moniz rapidly disseminated his results through articles in the medical press and a monograph in 1936. Initially, however, the medical community appeared hostile to the new procedure. On 26 July 1936, one of his assistants, Diogo Furtado, gave a presentation at the Parisian meeting of the Société
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Pedro Almeida Lima, as early as 1933 of his psychosurgical idea. The traditional account exaggerates the importance of Fulton and Jacobsen to Moniz's decision to initiate frontal lobe surgery, and omits the fact that a detailed body of neurological research that emerged at this time suggested to
668:. He differed significantly from Burckhardt, however in that he did not think there was any organic pathology in the brains of the mentally ill, but rather that their neural pathways were caught in fixed and destructive circuits leading to "predominant, obsessive ideas". As Moniz wrote in 1936:
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The hypotheses underlying the procedure might be called into question; the surgical intervention might be considered very audacious; but such arguments occupy a secondary position because it can be affirmed now that these operations are not prejudicial to either physical or psychic life of the
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Intending to ameliorate symptoms in those with violent and intractable conditions rather than effect a cure, Burckhardt began operating on patients in December 1888, but both his surgical methods and instruments were crude and the results of the procedure were mixed at best. He operated on six
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patient. In Romania, Ody's procedure was adopted by Dimitri Bagdasar and Constantinesco working out of the Central Hospital in Bucharest. Ody, who delayed publishing his own results for several years, later rebuked Moniz for claiming to have cured patients through leucotomy without waiting to
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The frontal lobotomy procedure had severe negative effects on a patient's personality and ability to function independently. Lobotomy patients often show a marked reduction in initiative and inhibition. They may also exhibit difficulty imagining themselves in the position of others because of
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be used to render the patient unconscious.) In 1947, the Freeman and Watts partnership ended, as the latter was disgusted by Freeman's barbarism and neglectful modifications of the lobotomy from a surgical operation into a simple "office" procedure. Between 1940 and 1944, 684 lobotomies were
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and, most dramatically, to a presentation Fulton made with his junior colleague Carlyle Jacobsen at the Second International Congress of Neurology held in London in 1935. Fulton's primary area of research was on the cortical function of primates and he had established America's first primate
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Leucotomy was first reported in the Italian medical press in 1936 and Moniz published an article in Italian on the technique in the following year. In 1937, he was invited to Italy to demonstrate the procedure and for a two-week period in June of that year he visited medical centres in
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magazine article remarked that the nation's system of mental hospitals resembled "little more than concentration camps on the Belsen pattern"; a point the piece emphasized with documentary photography that depicted patient neglect and dilapidated material conditions within psychiatric
1440:, which allowed routine visualisation of the brain's peripheral blood vessels for the first time, he was twice nominated, unsuccessfully, for a Nobel Prize. Some have attributed his development of leucotomy to a determination on his part to win the Nobel after these disappointments.
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provided a guiding hand. Under the medical directorship of Emilio Rizzatti, the medical personnel at this hospital had completed at least 200 leucotomies by 1939. Reports from clinicians based at other Italian institutions detailed significantly fewer leucotomy operations.
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The clinician-historian Joel Braslow argues that from malarial therapy onward to lobotomy, physical psychiatric therapies "spiral closer and closer to the interior of the brain" with this organ increasingly taking "center stage as a source of disease and site of cure". For
808:. Nonetheless, Moniz's reported successful surgical treatment of 14 out of 20 patients led to the rapid adoption of the procedure on an experimental basis by individual clinicians in countries such as Brazil, Cuba, Italy, Romania and the United States during the 1930s.
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Moniz, then 51 years old, devoted his considerable talents and energies to neurological research entirely. Throughout his career he published on topics as diverse as neurology, sexology, historical biography, and the history of card games. For his 1927 development of
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Lobotomies have been featured in several literary and cinematic presentations that both reflected society's attitude toward the procedure and, at times, changed it. Writers and film-makers have played a pivotal role in turning public sentiment against the procedure.
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The theoretical underpinnings of Moniz's psychosurgery were largely commensurate with the nineteenth-century ones that had informed Burckhardt's decision to excise matter from the brains of his patients. Although in his later writings Moniz referenced both the
511:. First developing an interest in psychiatric conditions and their somatic treatment in the early 1930s, Moniz apparently conceived a new opportunity for recognition in the development of a surgical intervention on the brain as a treatment for mental illness.
1052:, said: "Prefrontal lobotomy... has recently been having a certain vogue, probably not unconnected with the fact that it makes the custodial care of many patients easier. Let me remark in passing that killing them makes their custodial care still easier."
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Professor of neurology at the University of Lisbon from 1911 to 1944, Moniz was also for several decades a prominent parliamentarian and diplomat. He was Portugal's ambassador to Spain during World War I and represented Portugal at the postwar
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the procedure adopted a cautious approach and few patients were leucotomised before the 1940s. Italian neuropsychiatrists, who were typically early and enthusiastic adopters of leucotomy, were exceptional in eschewing such a gradualist course.
397:. He reasoned, however, that removing material from either of the sensory or motor zones could give rise to "grave functional disturbance". Instead, by targeting the association centers and creating a "ditch" around the motor region of the
1381:, described psychiatry during the interwar period as a "funereal science". Likewise Egas Moniz, the inventor of leucotomy, referred to the "impotência terapeutica" (therapeutic impotence) of existing therapeutic remedies during the 1930s.
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Nor was Moniz the only medical practitioner in the 1930s to have contemplated procedures directly targeting the frontal lobes. Although ultimately discounting brain surgery as carrying too much risk, physicians and neurologists such as
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in 1848, this constituted an "accidental lobotomy", or that this event somehow inspired the development of surgical lobotomy a century later. According to the only book-length study of Gage, careful inquiry turns up no such
213:. A large number of patients were gay men. More lobotomies were performed on women than on men: a 1951 study found that nearly 60% of American lobotomy patients were women, and limited data shows that 74% of lobotomies in
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describes a lobotomy as making "a Comanche brave look like a tyro with a scalping knife", and portrays the surgeon as a repressed man who cannot change others with love, so he instead resorts to "high-grade carpentry
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system (a motor center); and, finally, a modular conception of the brain whereby discrete mental faculties were connected to specific regions of the brain. Burckhardt's hypothesis was that by deliberately creating
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We have quoted this data to show not only how groundless but also how dangerous these operations were. We are unable to explain how their author, holder of a degree in medicine, could bring himself to carry them
1252:(the subject of the film) undergoing transorbital lobotomy (though the idea that a lobotomy was performed on Farmer, and that Freeman performed it, has been criticized as having little or no factual foundation).
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has sometimes been claimed as the father of lobotomy, was later able to record that the technique had its true origination in his laboratory. Endorsing this version of events, in 1949, the Harvard neurologist
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for a hypodermic needle, it is estimated that he leucotomised about 100 patients in the period up to the outbreak of World War II. Fiamberti's innovation of Moniz's method would later prove inspirational for
437:". Claiming a success rate of 50 percent, he presented the results at the Berlin Medical Congress and published a report, but the response from his medical peers was hostile and he did no further operations.
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The Soviet Union officially banned the procedure in 1950 on the initiative of Gilyarovsky. Doctors in the Soviet Union concluded that the procedure was "contrary to the principles of humanity" and
4555:. Effect of therapeutic innovation on perception of disease and the doctor-patient relationship: a history of general paralysis of the insane and malaria fever therapy, 1910–1950.
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as a mainstream procedure in some countries. The procedure was controversial from its initial use, in part due to a lack of recognition of the severity and chronicity of severe and enduring
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6108:. A psychosurgical chapter in the history of cerebral localization: the six cases of Gottlieb Burkhardt. In: Code, Christopher; Wallesch, C.-W.; Joanette Y.; Roch A. (eds).
5714:. Neurosurgery for psychiatric disorders: from the excision of brain tissue to the chronic electrical stimulation of neural networks. In: Sakas, D.E.; Simpson, B.A. (eds).
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1453:. Freeman, who would later play a central role in the popularisation and practice of leucotomy in America, also had an interest in personality changes following frontal lobe surgery.
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bone at the top of the socket and then inject alcohol or formalin into the white matter of the frontal lobes through this aperture. Using this method, while sometimes substituting a
359:
Before the 1930s, individual doctors had infrequently experimented with novel surgical operations on the brains of those deemed insane. Most notably in 1888, the Swiss psychiatrist
5208:Судьбы больных шизофренией: клинико-социальный и судебно-психиатрический аспекты [The fates of the ill with schizophrenia: clinico-social and forensico-psychiatric aspects]
5078:. Egas Moniz (1874–1955) and the "invention" of modern psychosurgery: a historical and ethical reanalysis under special consideration of Portuguese original sources.
1055:
Concerns about lobotomy steadily grew. Soviet psychiatrist Vasily Gilyarovsky criticized lobotomy and the mechanistic brain localization assumption used to carry out lobotomy:
5604:
5156:
Joanette, Yves; Stemmer, Brigitte; Assal, Gil; Whitaker, Harry. From theory to practice: the unconventional contribution of Gottlieb Burckhardt to psychosurgery.
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according to the knowledge and technology of the time as the absence of a known correlation between physical brain pathology and mental illness could not disprove his thesis.
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the brain. Under an evolutionary and hierarchical model of brain development it had been hypothesized that those regions associated with more recent development, such as the
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Cooper, Rachel. On deciding to have a lobotomy: either lobotomies were justified or decisions under risk should not always seek to maximise expected utility.
571:
of the frontal lobes. This picture of the so-called "silent lobe" changed in the period after World War I with the production of clinical reports of ex-servicemen with
1235:, portrays the dehumanizing lobotomy of a womanizing, quarrelsome poet who, afterward, is just as aggressive as ever. The surgeon is depicted as an inhumane crackpot.
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each lobe, but, if they were dissatisfied by the results, Lima might perform several procedures, each producing multiple lesions in the left and right frontal lobes.
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1354:
all hospital beds in America. Conditions within US mental hospitals became the subject of public debate as a series of exposes were published in the 1940s. A 1946
6201:
Out of Sight, Out of Mind: A Graphic Picture of Present-day Institutional Care of the Mentally Ill in America, Based on More Than Two Thousand Eye-witness Reports
1261:
centers on lobotomy, attitudes about mental health in general, in 1950s America. The protagonist, a young man whose mother had been lobotomized, takes a job as a
894:, first devised the transorbital procedure whereby the frontal lobes were accessed through the eye sockets. Fiamberti's method was to puncture the thin layer of
711:. The intention was to remove some of the long fibres that connected the frontal lobes to other major brain centres. To this end, it was decided that Lima would
5347:
Manjila, S.; Rengachary, S.; Xavier, A.R.; Parker, B.; Guthikonda, M.. Modern psychosurgery before Egas Moniz: a tribute to Gottlieb Burckhardt.
1137:' older sister Rose received a lobotomy that left her incapacitated for life; the episode is said to have inspired characters and motifs in some of his works.
939:
ahead". Moniz, in return, promised to send him a copy of his forthcoming monograph on leucotomy and urged him to purchase a leucotome from a French supplier.
5377:
Mareke, Arends; Fangerau, Heiner. Deep brain stimulation in psychiatric disorders. In: Fangerau, Heiner; Jörg, Fegert; Mareke, Arends (eds).
981:, Freeman at some point conceived of approaching the frontal lobes through the eye sockets instead of through drilled holes in the skull. In 1945 he took an
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of 1949 for the "discovery of the therapeutic value of leucotomy in certain psychoses", although the awarding of the prize has been subject to controversy.
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The authors neglected to mention, however, that in 1910 Puusepp himself had performed surgery on the brains of three mentally ill patients, sectioning the
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utilized media coverage and penned editorials for numerous interviews promoting the procedure and achieving accolades for his work in psychiatric care.
5638:. Alcune considerazioni sugli interventi chirurgici nelle malattie mentali [Some Considerations about Surgery in Mental Illness].
562:
Moniz and other neurologists and neurosurgeons that surgery on this part of the brain might yield significant personality changes in the mentally ill.
6068:. Contributing editors Dagi, T. Forcht; Epstein, Mel H.. Park Ridge, IL: The American Association of Neurological Surgeons; 1997.
6040:. The Prefrontal Area and Psychosurgery. In: Uylings, H.B.M.; Van Eden, C.G.; De Bruin, J.P.C.; Corner, M.A.; Feenstra, M.G.P. (eds).
5227:
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The use of the procedure increased dramatically from the early 1940s and into the 1950s; by 1951, almost 20,000 lobotomies had been performed in the
1068:'through lobotomy' an insane person is changed into an idiot". By the 1970s, numerous countries had banned the procedure, as had several US states.
5106:. Some continuities and discontinuities in the pharmacotherapy of nervous conditions before and after chlorpromazine and imipramine.
1344:, who was the joint winner with Moniz of the Nobel Prize in 1949 for his work on the function of the midbrain, had no involvement with leucotomy.
598:
in 1930. The neurologist Richard Brickner reported on this case in 1932, relating that the recipient, known as "Patient A", while experiencing a
85:
1322:
1123:, a Polish violinist and composer, was diagnosed with schizophrenia and died at the age of 26 following a lobotomy performed on him in England.
1009:
the hospital reprimanded Freeman, stating that he was “not a surgeon and if he wants to operate he’ll have to apply for surgical privileges.”
5987:
923:
The first prefrontal leucotomy in the United States was performed at the George Washington University Hospital, on 14 September 1936, by the
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Experimental modifications of Moniz's operation were introduced with little delay by Italian medical practitioners. Most notably, in 1937
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neurophysiology laboratory at Yale in the early 1930s. At the 1935 Congress, with Moniz in attendance, Fulton and Jacobsen presented two
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may have arrangements more or less fixed, which will have a relation with persistent ideas and deliria in certain morbid psychic states.
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patients in total and, according to his own assessment, two experienced no change, two patients became quieter, one patient experienced
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19:
This article is about the operation that severs connections within the brain. For the operation that removes a lobe of the brain, see
1207:
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were another common complication of surgery. Emphasis was put on the training of patients in the weeks and months following surgery.
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Protection on Human Subjects: Use of Psychosurgery in Practice and Research: Report and Recommendations for Public Comment. Part 3
4476:
6675:
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161:
5946:. Egas Moniz and the Origins of Psychosurgery: A Review Commemorating the 50th Anniversary of Moniz's Nobel Prize.
4599:. An interpretation of frontal lobe function based upon the study of a case of partial bilateral frontal lobotomy.
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199:
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Zajicek, Benjamin (2017). "Banning the Soviet Lobotomy: Psychiatry, Ethics, and Professional Politics during Late Stalinism".
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Frontal leukotomy and related psychosurgical procedures in the era before antipsychotics (1935–1954): a historical overview
1479:
Brickner and Davidoff had planned, before Moniz's first leucotomies, to operate on the frontal lobes to relieve depression.
4065:(French national consultative committee on ethics, opinion #71: Functional neurosurgery of severe psychiatric conditions)
217:
from 1948 to 1952 were performed on female patients. From the 1950s onward, lobotomy began to be abandoned, first in the
4622:
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1726:
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1702:
4394:"'The Mountain' Review: Jeff Goldblum and Tye Sheridan Are Lost Souls in Rick Alverson's Beautiful, Fractured America"
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The American neuropsychiatrist Walter Freeman also attended the Congress where he presented his research findings on
553:
4886:. Functional neurosurgical intervention: neuroethics in the operating rooms. In: Illes, Judy (ed.).
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and limited budgets. Freeman wanted to simplify the procedure so that it could be carried out by psychiatrists in
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and concluded that she underwent a lobotomy for the treatment of pain and anxiety in the last months of her life.
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to rescind the award; the Foundation has not done so, and its website still hosts an article defending lobotomy.
575:. The refinement of neurosurgical techniques also facilitated increasing attempts to remove brain tumours, treat
6226:
367:. He operated on six chronic patients under his care at the Swiss Préfargier Asylum, removing sections of their
6802:
6792:
5894:
5058:
4972:. Учение Павлова – основа психиатрии [Pavlov's teaching is the basis of psychiatry].
4557:
1759:
401:, he hoped to break their lines of communication and thus alleviate both mental symptoms and the experience of
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664:, in essence he simply interpreted this new neurological research in terms of the old psychological theory of
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Site of borehole for the standard pre-frontal lobotomy/leucotomy operation as developed by Freeman and Watts
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narrow localizationism characteristic of psychiatrists of America, from where leucotomy was imported to us.
543:
highlighted in red. Moniz targeted the frontal lobes in the leucotomy procedure he first conceived in 1933.
1111:, underwent a lobotomy in 1941 that left her incapacitated and institutionalized for the rest of her life.
425:
and died a few days after the operation, and one patient improved. Complications included motor weakness,
6524:
6046:. Amsterdam & New York: Elsevier; 1990. (Progress in Brain Research, Volume 85).
5467:
PREFRONTAL LEUCOTOMY IN THE TREATMENT OF MENTAL DISORDERS (1937) American Journal of Psychiatry 1844–1944
1098:
878:. The major centre for leucotomy in Italy was the Racconigi Hospital, where the experienced neurosurgeon
6244:
5466:
4613:
Why Wagner-Jauregg won the Nobel Prize for discovering malaria therapy for General Paresis of the Insane
6179:
5652:
4427:
5380:
Implanted Minds: The Neuroethics of Intracerebral Stem Cell Transplantation and Deep Brain Stimulation
4425:
Acharya, Hernish J.. The Rise and Fall of Frontal Leucotomy. In: Whitelaw, W.A. (ed).
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5030:. Functional and epilepsy neurosurgery. In: Johnson, Reuben; Green, Alexander (eds).
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According to Puusepp, the three patients had manic depression or considered "epileptic equivalents".
6743:
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5486:. New evidence of prefrontal lobotomy in the last months of the illness of Eva Perón.
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904:
92:
4658:. Neuropatients in Historyland. In: Jacyna, Stephen J.; Casper, Stephen T. (eds).
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Bechterev, V.; Puusepp, L.. La chirugie des aliénes [Surgery of the Insane].
1533:
The 14 leucotomies reported by Puusepp in his 1937 paper were performed at the Racconigi Hospital.
6557:
6234:
Macmillan, Malcolm. The Center for the History of Psychology, University of Akron, Ohio.
5889:
5717:
Operative Neuromodulation. Functional Neuroprosthetic Surgery. Volume II: Neural Networks Surgery
5002:
4793:
The Lobotomist: A Maverick Medical Genius and His Tragic Quest to Rid the World of Mental Illness
1223:, the protagonist reacts with horror to the "perpetual marble calm" of a lobotomized young woman.
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Mental Ills and Bodily Cures: Psychiatric Treatment in the First Half of the Twentieth Century
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6028:. Приказ МЗ СССР 1003 (9 декабря 1950) [Order 1003 (9 December 1950)].
5620:
The Greatest Benefit to Mankind: A Medical History of Humanity from Antiquity to the Present
1553:
a carload of grapefruit, getting the right move and the right turn. That's what he told me."
594:
The first bilateral lobectomy of a human subject was performed by the American neurosurgeon
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to establish it as an early and influential centre for the adoption of leucotomy in Italy.
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wrote a memoir of his late-life discovery that he had been lobotomized in 1960 at age 12.
607:
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Albert Q. Maisel, "Bedlam 1946, Most U.S. Mental Hospitals are a Shame and a Disgrace",
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5128:. Surgery of the mind and mood: A mosaic of issues in time and evolution.
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In 1937 Freeman and Watts adapted Lima and Moniz's surgical procedure, and created the
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patient, and also that recovery or improvement may be obtained frequently in this way.
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238:
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5139:
Hoenig, J.. Schizophrenia. In: Berrios, German E.; Porter, Roy (eds).
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In 2011, Daniel Nijensohn, an Argentine-born neurosurgeon at Yale, examined X-rays of
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age; twelve were female and eight were male. Nine of the patients were diagnosed with
582:
233:
Historically, patients of frontal lobotomy were, immediately following surgery, often
6787:
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4773:
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4506:. New York & Edinburgh: William Wood & Co; E.S Livingstone; 1922.
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Bangen, Hans: Geschichte der medikamentösen Therapie der Schizophrenie. Berlin 1992,
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functionally adapt to such injury. Unlike the position adopted by Burckhardt, it was
526:
497:
422:
165:
80:
64:
6175:
Therapy 101: A Brief Look at Modern Psychotherapy Techniques & How They Can Help
5816:. Milestones in the development of neurology and psychiatry in Europe.
4601:
Research Publications – Association for Research for Nervous end Mental Disease
4008:
1845:
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379:(a sensory center), a connecting system where information processing took place (an
168:. The surgery causes most of the connections to and from the prefrontal cortex, the
43:
6700:
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5821:
5761:
Overcoming Depression Without Drugs: Mahler's Polka With Introductory Funeral March
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4928:. Psychosurgery: An Evaluation of Two Hundred Cases over Seven Years.
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It is often said that when an iron rod was accidentally driven through the head of
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978:
887:
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initiated what is commonly considered the first systematic attempt at modern human
304:
249:
6220: [podcast]; 16 November 2005 [Retrieved 28 November 2009].
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Before operating on live subjects, they practised the procedure on a cadaver head.
653:
6733:
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6638:
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My Lobotomy Radio story: Interview with Sallie Ellen Ionesco, lobotomised in 1946
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A History of Clinical Psychiatry: The Origin and History of Psychiatric Disorders
5032:
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4888:
4866:
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4535:
4516:
4057:
3956:"Jesper Vaczy Kragh: "Sidste udvej? Træk af psykokirurgiens historie i Danmark" (
1517:
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149:
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3856:"Psychosurgery, ethics, and media: a history of Walter Freeman and the lobotomy"
3804:"Psychosurgery, ethics, and media: a history of Walter Freeman and the lobotomy"
3776:
6545:
6457:
5650:. Psychosurgery, Industry and Personal Responsibility, 1940–1965.
5495:
5117:
5087:
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4502:
4484:
4371:"A Lobotomist Struggles To Hang on in the Brilliant, Blistering 'The Mountain'"
1644:
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Music's boy wonder: Composer, conductor, singer ... and he's only fifteen
5275:
5194:
Something Cloudy, Something Clear: Tennessee Williams's Postmodern Memory Play
5011:
4647:
3872:
3855:
3820:
1787:(9th ed.). Belmont, California: Wadsworth/Thomson Learning. p. 101.
6781:
6492:
6353:
6225:
Jansson, Bengt. Nobel Media [Retrieved 24 January 2012].
6062:. History of Psychosurgery. In: Greenblatt, Samuel H. (ed.).
6017:
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71:
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6086:
Neurosurgical intervention for psychiatric illness: past, present and future
5825:
5553:
1081:
has called the award of the Nobel Prize to Moniz an "astounding of judgment
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Cybernetics: Or the Control and Communication in the Animal and the Machine
942:
Upon receipt of Moniz's monograph, Freeman reviewed it anonymously for the
723:
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Lima described his role as that of an "instrument handled by the Master".
924:
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661:
536:
532:
500:
489:
The pioneer of lobotomies, the Portuguese neurologist and Nobel Laureate
177:
5836:. Gottlieb Burckhardt – The Pioneer of Psychosurgery.
5739:
A History of Psychiatry: From the Era of the Asylum to the Age of Prozac
5218:
Gottlieb Burckhardt and Egas Moniz – Two Beginnings of Psychosugery
408:
279:
6613:
6384:
5322:
4956:. 2nd ed. American Psychiatric Publishing, Inc.; 1999.
1667:"The dark history of gay men, lobotomies and Walter Jackson Freeman II"
1463:
1374:
967:
801:
332:
6245:
The Nobel Prize in Physiology or Medicine 1949 Walter Hess, Egas Moniz
6065:
A History of Neurosurgery: In Its Scientific and Professional Contexts
4867:
Origins of Neuroscience: A History of Explorations into Brain Function
4732:
Diefenbach, Gretchen; Diefenbach, Donald; Baumeister, Alan; West, Mark
4664:. Rochester, NY: University of Rochester Press; 2012.
4479:
30 December 2009; Retrieved 28 November 2009];8(1):61–81.
347:
241:. Some developed an enormous appetite and gained considerable weight.
108:
6695:
6628:
6623:
5902:
24 July 2008; Retrieved 29 November 2010];152(4):505–15.
5361:
5230:
15 December 2011; Retrieved 26 November 2009];62(1/2):77–101.
4517:
A Critical Introduction to Twentieth-Century American Drama: Volume 2
4047:"La neurochirurgie fonctionnelle d'affections psychiatriques sévères"
3631:
3629:
1298:
1197:
899:
847:
780:
760:
731:
320:
303:" physical therapies devised during this experimental era, including
234:
47:
20:
4912:. 2nd ed. Belmont, California: Wadsworth; 2010.
3777:"Psychiatry | Mental Health, Treatment & Diagnosis | Britannica"
6578:
6483:
6414:
5222:
5062:. 1978 [Retrieved 22 January 2008];2(1):29–44.
1467:
1277:
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of the prefrontal area" so as to destroy the connecting fibres, or
712:
426:
287:
242:
169:
157:
5340:
Bedlam 1946, Most U.S. Mental Hospitals are a Shame and a Disgrace
5235:
Kotowicz, Zbigniew. Psychosurgery in Italy, 1936–39.
4730:
4228:
4017:
3626:
3292:
3290:
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2678:
985:
from his own kitchen and began testing the idea on grapefruit and
496:
Leucotomy was first undertaken in 1935 under the direction of the
5712:
Sakas, Damianos E.; Panourias, L.G.; Singounas, E.; Simpson, B.A.
4322:
2998:
2996:
2505:
2503:
2501:
2499:
982:
871:
851:
839:
835:
735:
716:
214:
6088:. In: Miller, Bruce L.; Cummings, Jeffrey L. (eds).
5930:. New Brunswick, New Jersey: Transaction; 2007.
5181:
Kaempffert, Waldemar. Turning the Mind Inside Out.
4889:
Neuroethics: defining the issues in theory, practice, and policy
4503:
The Mechanism of the Brain and the Function of the Frontal Lobes
3936:
3924:
1933:
1931:
1929:
1861:"A brief reflection on the not-so-brief history of the lobotomy"
37:
5590:. Cambridge: Cambridge University Press; 2002.
5514:
The encyclopedia of schizophrenia and other psychotic disorders
5406:. 30 January 2004 [Retrieved 17 November 2007].
4815:
The Nobel prize: a history of genius, controversy, and prestige
3285:
1390:
The patient he thought improved subsequently committed suicide.
1239:
891:
875:
855:
704:
389:
299:
which had prevailed since the mid-nineteenth-century. The new "
222:
5805:
An Introduction to Physical Methods of Treatment in Psychiatry
5710:
5576:. Oxford: Blackwell Scientific Publications; 1950.
4288:
4286:
4284:
3900:
2993:
2496:
2464:
2285:
5346:
4988:. Moscow: Медицина ; 1973. Russian. p. 4.
3545:
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3389:
2398:
2249:
1926:
1524:
that 15,000 leucotomies had been performed in the UK by 1962.
915:
863:
859:
843:
756:
474:
6292:'My Lobotomy': Howard Dully's Journey. NPR Radio Documentary
6043:
The Prefrontal Cortex: Its Structure, Function and Pathology
5155:
4688:. 12 January 2008 [Retrieved 31 March 2010].
2983:
2981:
2968:
2966:
2241:
2083:
2081:
6204:. Philadelphia: Mental Health Foundation; 1947.
5613:. 6 February 2008 [Retrieved 11 July 2010].
5534:. Philadelphia and London: W.B. Saunders; 1962.
4428:
The Proceedings of the 13th Annual History of Medicine Days
4281:
3562:
3560:
3517:
3448:
3422:
3420:
2861:
2859:
1916:
1914:
1899:
1887:
1727:"Race and Gender in the Selection of Patients for Lobotomy"
1186:
1085:... a terrible mistake", and there have been calls for the
867:
626:
had, before 1935, entertained the proposition. Inspired by
248:
The purpose of the operation was to reduce the symptoms of
5674:
The lobotomy letters: the making of American psychosurgery
5313:. On the history of psychosurgery in Russia.
5211:. Moscow: ЗАО Юстицинформ ; 2010. Russian.
5028:
Green, Alexander; Astradsson, A.; Stacey, R.J.; Aziz, T.Z.
4068:
3888:
3720:
3718:
3705:
3703:
3701:
3673:
3386:
3275:
3273:
3271:
3212:
2801:
2553:
2551:
2549:
2547:
2545:
2543:
2541:
2437:
2435:
2404:
2118:
2116:
2054:
6256:; 5 August 2004 [Retrieved 22 December 2011].
5447:
Meduna, L.J.. Autobiography of L.J. Meduna.
5297:. Oxford: Oxford University Press; 1991.
5026:
4870:. Oxford: Oxford University Press; 2001.
4269:
4119:
3577:
3575:
3319:, p. 651. For Moniz's account of the procedure see,
3074:
2978:
2963:
2928:
2926:
2924:
2922:
2920:
2891:
2889:
2826:
2824:
2822:
2820:
2818:
2816:
2749:
2695:
2693:
2325:
2281:
2078:
1955:
1606:
1265:
for a doctor whose character is loosely based on Freeman.
4467:
The Origins of Psychosurgery: Shaw, Burckhardt and Moniz
4131:
4092:
3802:
Caruso, James P.; Sheehan, Jason P. (1 September 2017).
3557:
3460:
3417:
3170:
3168:
2856:
2773:
2644:
2642:
2342:
2340:
2315:
2313:
2300:
2298:
1911:
1627:
1625:
1623:
1621:
630:'s development of malarial therapy for the treatment of
591:
its critics due to deficiencies in experimental design.
485:
194:
The originator of the procedure, Portuguese neurologist
6104:
6024:
5412:
Mashour, George A.; Walker, Erin E.; Martuza, Robert L.
4310:
4240:
4194:
4113:
4002:
3912:
3715:
3698:
3661:
3358:
3268:
3244:
3153:
2538:
2526:
2432:
2358:
2289:
2128:
2113:
1995:
1993:
1943:
890:, the medical director of a psychiatric institution in
4840:. March 2001;48(3):647–57; discussion 657–59.
4298:
4080:
3742:
3730:
3572:
3346:
3256:
3141:
2951:
2917:
2886:
2813:
2761:
2690:
2066:
6227:
Controversial Psychosurgery Resulted in a Nobel Prize
5587:
Last Resort: Psychosurgery and the Limits of Medicine
5470:. American Psychiatric Publishing; 1994.
4834:. Psychosurgery: A Historical Overview.
4736:
Portrayal of lobotomy in the popular press: 1935–1960
3759:
3757:
3437:
3435:
3165:
2906:
2904:
2737:
2639:
2627:
2563:
2380:
2337:
2310:
2295:
2199:
2187:
1978:
1618:
448:
and his younger Estonian colleague, the neurosurgeon
5410:
5126:
Heller, A. C.; Amar, A.P.; Liu, C.Y.; Apuzzo, M.L.J.
5054:
Of Graver Import Than History: Psychiatry in Fiction
4182:
3592:
3590:
2875:
2175:
2003:
1990:
1596:
1594:
1273:
1156:
164:) that involves severing connections in the brain's
6082:
Weiss, Anthony P.; Rauch, Scott L.; Price, Bruce H.
5754:
5676:. University of Rochester Press; 2013.
5124:
4334:
4234:
3836:
2715:
2684:
2672:
2515:
2368:
2237:
1373:, the Italian psychiatrist and joint inventor with
1179:Tennessee Williams criticized lobotomy in his play
1071:In 1977, the US Congress, during the presidency of
783:, as well as psychological effects such as apathy,
703:On 12 November 1935 at the Hospital Santa Marta in
639:determine if there had been a "lasting remission".
191:, so it was said to be an inappropriate treatment.
6278:article on lobotomy and contemporary psychosurgery
6238:; 1999–2012 [Retrieved 21 March 2009].
5928:Coercion as Cure: A Critical History of Psychiatry
5542:. Psychosurgery in Sweden 1944–1964.
4682:He was bad, so they put an ice pick in his brain..
4217:
4165:Coercion as Cure: A Critical History of Psychiatry
3754:
3432:
2901:
1967:
183:In the past, this treatment was used for treating
6307:Nobel Panel Urged to Rescind Prize for Lobotomies
5517:. Infobase Publishing; January 2007.
4143:
3587:
1591:
930:, and his friend and colleague, the neurosurgeon
520:reference to the work of the Yale neuroscientist
264:decreased cognition and detachment from society.
6779:
6114:. Hove: Psychology Press; 1996.
6090:The Human Frontal Lobes: Functions and Disorders
5690:Reevy, Gretchen; Ozer, Yvette Malamud; Ito, Yuri
4520:. Cambridge University Press; 1985.
4455:
4206:
2422:
1697:. University of Michigan Press. pp. 50–60.
552:remarked during his presidential address to the
393:transmitted to the motor regions giving rise to
6247:; 2013 [Retrieved 24 January 2013].
6080:
5818:Schweizer Archiv für Neurologie und Psychiatrie
4830:
3639:
3604:
3478:
3336:
3316:
3296:
3190:
3135:
3031:
3002:
2509:
2470:
2027:
1999:
1574:"Lobotomy: Definition, Procedure & History"
580:lobes led to the formulation of the concept of
6242:
6233:
5994:
5376:
5290:
5006:. 21 September 1996;313(7059):708–09.
4946:
4726:. New York: Harcourt, Brace; 1948.
4583:. University of California; 1997.
4328:
4263:
3906:
2850:
2273:
1660:
1658:
1612:
1323:History of psychosurgery in the United Kingdom
6339:
6156:. Dramatists Play Service; 1998.
5798:
5538:
5036:. Oxford University Press; 2010.
4992:
4892:. Oxford University Press; 2006.
4882:
4074:
3942:
3930:
3853:
3801:
3511:
2277:
1645:"The strange and curious history of lobotomy"
1466:, a rare form of brain tumour arising in the
1185:(1958) because it was sometimes inflicted on
977:Inspired by the work of Italian psychiatrist
787:, lethargy, timing and local disorientation,
5688:
5398:Janet Frame, 79, Writer Who Explored Madness
5358:An Odd Kind of Fame: Stories of Phineas Gage
5291:Levin, Harvey S.; Eisenberg, Howard M..
5074:
4924:
4695:Department of Health, Education, and Welfare
3854:Caruso, James P.; Sheehan, Jason P. (2017).
3411:
3395:
3312:
3238:
3218:
3202:
3109:
3080:
2945:
2257:
2233:
2087:
256:and restricted in their intellectual range.
6236:The Phineas Gage Information Page: Lobotomy
5949:Journal of the History of the Neurosciences
5839:Journal of the History of the Neurosciences
5786:. Van Nostrand Reinhold; 1982.
5545:Journal of the History of the Neurosciences
4980:
4968:
4741:Journal of the History of the Neurosciences
4125:
4098:
1655:
955:Freeman-Watts standard prefrontal lobotomy,
715:into the side of the skull and then inject
622:, Thierry de Martel, Richard Brickner, and
6762:National Institutes of Health Stroke Scale
6346:
6332:
6251:
6058:
6036:
5720:. Vol. 2. Springer; 2007.
5309:
5180:
4976:. 14 September 1950;(37). Russian.
4109:
3990:
3340:
3068:
3055:
3051:
3027:
3015:
2987:
2972:
2795:
1937:
1774:
1631:
957:which they styled the "precision method".
775:, diarrhea, and ocular affections such as
36:
6106:Whitaker, H.A.; Stemmer, B.; Joanette, Y.
5568:
5529:
5482:
5355:
5204:
5048:
4292:
4275:
4259:
3871:
3819:
1905:
1893:
606:and reported on by the neuropsychiatrist
6168:
6146:
5580:
5416:Psychosurgery: Past, Present, and Future
5234:
5215:
5198:Journal of Dramatic Theory and Criticism
4986:Избранные труды [Selected Works]
4595:
4539:. 1st ed. TwoDot; 2005.
4316:
4137:
3724:
3709:
3692:
3679:
3667:
3655:
3651:
3635:
3620:
3566:
3551:
3539:
3523:
3507:
3482:
3466:
3454:
3442:
3426:
3380:
3364:
3332:
3279:
3250:
3234:
3206:
3186:
3159:
3122:
3105:
3035:
2957:
2932:
2911:
2895:
2881:
2869:
2865:
2846:
2830:
2807:
2791:
2767:
2755:
2727:
2711:
2699:
2660:
2589:
2557:
2532:
2486:
2482:
2445:
2441:
2426:
2410:
2245:
2217:
2122:
2060:
2048:
2031:
1642:
960:
914:
531:
484:
407:
346:
278:
6224:
6012:3 December 2007];16(1):107–10.
5942:
5808:. Williams & Wilkins; 1963.
5732:
5634:
5426:17 January 2013];48(3):409–19.
5187:. 24 May 1941;213(47):18–19, 69–74.
5112:. January 2000;11(44):393–412.
4904:
4818:. Arcade Publishing; 2001.
4808:
4716:
4573:
4551:
4499:
4464:
4424:
4200:
4188:
3894:
3616:
3535:
3407:
3376:
3352:
3308:
3230:
3147:
3093:
3047:
2842:
2779:
2743:
2731:
2668:
2664:
2648:
2621:
2605:
2601:
2585:
2581:
2569:
2521:
2490:
2458:
2386:
2362:
2346:
2331:
2319:
2304:
2181:
2169:
2165:
2150:
2146:
2072:
2023:
1961:
1807:
1694:American Lobotomy: A Rhetorical History
1690:
1423:negotiations, but after the Portuguese
6780:
6320:documentary on the history of lobotomy
6194:
6126:
5972:
5958:10.1076/0964-704X(200004)9:1;1-2;FT022
5884:
5776:
5617:
5446:
5395:
5337:
5241:. December 2008;19(4):476–89.
5138:
4860:
4832:Feldman, Robert P.; Goodrich, James T.
4786:
4654:
4637:
4625:4 January 2013];11(4):371–82.
4510:
4458:Archives Internationales de Neurologie
4435:
4431:. Calgary: 2004. p. 32–41.
4356:
4340:
4304:
4086:
3918:
3842:
3748:
3736:
3600:
3596:
3581:
3495:
3262:
2633:
2205:
2193:
2107:
2103:
2099:
2019:
2015:
1973:
1920:
1858:
1724:
907:development of transorbital lobotomy.
342:
200:Nobel Prize for Physiology or Medicine
6327:
6218:"My Lobotomy": Howard Dully's Journey
6215:
5922:
5862:
5832:
5812:
5602:
5463:
5294:Frontal Lobe Function and Dysfunction
5261:
5191:
5102:
4607:
4532:
4368:
4352:
4246:
4223:
4161:
4054:Comité Consultatif National d'Ethique
3763:
3320:
3174:
2374:
2359:Whitaker, Stemmer & Joanette 1996
2290:Whitaker, Stemmer & Joanette 1996
2269:
2265:
2261:
2161:
2134:
1949:
1780:
1229:'s 1964 novel and 1966 film version,
1038:Journal of Nervous and Mental Disease
910:
642:
6092:. Guilford Press; 2007.
6032:. 1951;20(1):17–18. Russian.
5872:. Guilford Press; 2011.
5510:
4768:
4692:
4640:Medicine, Health Care and Philosophy
4391:
4149:
2617:
2253:
1664:
1295:– destruction of a part of the brain
944:Archives of Neurology and Psychiatry
811:
685:
5978:Lobotomy in Scandinavian psychiatry
5869:Clinical Neuropsychology of Emotion
5668:
5646:
5622:. Fontana Press; 1999.
4998:Norway compensates lobotomy victims
4884:Ford, Paul J.; Henderson, Jaimie M.
4774:Cerebral Angiography and Egas Moniz
4748:23 March 2010];8(1):60–69.
4676:
4661:The Neurological Patient in History
4443:. Berkley Books; 1982.
4212:
2221:
1984:
1810:Bulletin of the History of Medicine
1600:
1035:As early as 1944, an author in the
13:
6297:A Qualified Defence of 'Then': QJM
5756:Snyder, John; Steffen-Fluhr, Nancy
5264:Shock Therapy in Danish Psychiatry
4712:18 June 2013];42(99):26317–32.
4561:. May 1995;152(2):660–65.
2004:Mashour, Walker & Martuza 2005
1643:Levinson, Hugh (8 November 2011).
1130:died following a lobotomy in 1948.
444:, the leading Russian neurologist
14:
6814:
6262:
5952:. April 2000;9(1):22–36.
5764:. AuthorHouse; 2012.
5432:10.1016/j.brainresrev.2004.09.002
4910:Discovering Biological Psychology
4779:American Journal of Roentgenology
4536:Myths and Mysteries of Washington
2047:20 (1946), pp. 102–03, quoted in
1725:El-Hai, Jack (21 December 2016).
1157:Literary and cinematic portrayals
554:American Neurological Association
440:In 1912, two physicians based in
6619:Intervertebral disc annuloplasty
6473:Intracranial pressure monitoring
6111:Classic Cases in Neuropsychology
6000:Lobotomy in Norwegian Psychiatry
5983:The Journal of Mind and Behavior
5800:Sargant, William; Slater, Elliot
4926:Freeman, Walter; Watts, James W.
4846:10.1097/00006123-200103000-00041
4385:
4362:
4346:
4252:
4155:
4103:
4039:
4023:
3996:
3984:
3948:
3847:
3795:
3769:
3685:
3645:
3610:
3529:
3501:
3488:
3472:
3401:
3370:
3326:
3302:
3224:
3196:
3180:
3128:
3115:
3099:
2663:, pp. 13–14, 48–51, 54–55;
1546:
1536:
1527:
1510:
1501:
1492:
1482:
1276:
1092:
514:
295:with the psychiatric culture of
6134:. MIT Press; 1948.
5490:. 2012;77(3-4):582–90.
5076:Gross, Dominik; Schäfer, Gereon
5033:Landmark Papers in Neurosurgery
4948:Gabbard, Glen O.; Gabbard, Krin
4934:. 1944;90(379):532–37.
4235:Snyder & Steffen-Fluhr 2012
4056:. 25 April 2002. Archived from
3086:
3061:
3041:
3021:
3008:
2938:
2836:
2785:
2721:
2705:
2654:
2611:
2595:
2575:
2476:
2451:
2416:
2352:
2227:
2211:
2155:
2140:
2093:
2037:
2009:
1859:Gallea, Michael (Summer 2017).
1852:
1801:
1744:
1473:
1456:
1443:
1412:
1402:
1393:
1384:
1364:
1347:
1203:One Flew Over the Cuckoo's Nest
209:and proportionally more in the
6170:Wood, Jeffrey C.; Wood, Minnie
5996:Tranøy, Joar; Blomberg, Wenche
5895:American Journal of Psychiatry
5698:. ABC-CLIO; 2010.
5200:. Spring 1998;12(2):35–55.
5059:Journal of Libertarian Studies
4558:American Journal of Psychiatry
4369:Lapin, Andrew (25 July 2019).
1718:
1684:
1636:
1566:
1335:
966:operating rooms, surgeons, or
480:
1:
6757:Mini–mental state examination
5820:. 2010;161(3):85–89.
5783:Lobotomy: resort to the knife
5656:. 2009;23(1):116–33.
5548:. 2005;14(4):353–67.
5530:Noyes, A.P.; Kolb, L.C..
5317:. 1993;125(1–4):1–4.
5270:. 2010;54(3):341–64.
5216:Kotowicz, Zbigniew.
5160:. 1993;45(4):572–87.
5143:. Athlone; 1995.
4642:. 2014;17(1):143–54.
4465:Berrios, German E..
4392:Kohn, Eric (30 August 2018).
3605:Weiss, Rauch & Price 2007
1431:(National Dictatorship), the
1021:
632:general paresis of the insane
375:model comprising an input or
309:general paresis of the insane
6510:Multiple subpial transection
6216:Dully, Howard. NPR.
6030:Невропатология и психиатрия
5990:26 May 2008];17(1):1–20.
5842:. 2001;10(1):79–92.
5383:. Verlag; 2010.
4168:. Transaction. p. 165.
4114:USSR Ministry of Health 1951
4003:USSR Ministry of Health 1951
3958:Dansk Medicinhistorisk Årbog
2423:Bechterev & Puusepp 1912
1665:Kaye, Hugh (25 April 2023).
1559:
1030:
794:
7:
6525:Anterior temporal lobectomy
6254:Should they de-Nobel Moniz?
5742:. Wiley; 1997.
5451:. 1985;1(1):43–57.
4796:. Wiley; 2005.
4708:. 23 May 1977 [
3640:Feldman & Goodrich 2001
3479:Feldman & Goodrich 2001
3337:Feldman & Goodrich 2001
3317:Feldman & Goodrich 2001
3297:Feldman & Goodrich 2001
3191:Feldman & Goodrich 2001
3136:Feldman & Goodrich 2001
3032:Feldman & Goodrich 2001
3003:Feldman & Goodrich 2001
2510:Feldman & Goodrich 2001
2471:Feldman & Goodrich 2001
2028:Feldman & Goodrich 2001
2000:Feldman & Goodrich 2001
1269:
1099:Category:Lobotomised people
10:
6819:
6180:New Harbinger Publications
5653:Social History of Medicine
5532:Modern clinical psychiatry
5496:10.1016/j.wneu.2011.02.036
5118:10.1177/0957154X0001104405
5088:10.3171/2010.10.FOCUS10214
4631:10.1177/0957154X0001104403
4485:10.1177/0957154X9700802905
4460:. 1912;34:1–17, 69–89.
4412:
4329:Gabbard & Gabbard 1999
3907:Tranøy & Blomberg 2005
3219:, Gross & Schäfer 2011
2851:Levin & Eisenberg 1991
2274:Mareke & Fangerau 2010
2258:Reevy, Ozer & Ito 2010
1126:Swedish modernist painter
1096:
503:(and inventor of the term
412:The Estonian neurosurgeon
323:shock therapy (1934), and
274:
228:
18:
6744:Clinical prediction rules
6742:
6709:
6637:
6595:
6577:
6533:
6481:
6446:
6412:
6403:
6390:Decompressive craniectomy
6375:
6366:
5848:10.1076/jhin.10.1.79.5634
5276:10.1017/S0025727300004646
5012:10.1136/bmj.313.7059.708a
4953:Psychiatry and the Cinema
4931:Journal of Mental Science
4648:10.1007/s11019-013-9519-8
4075:Ogren & Sandlund 2005
3931:Ogren & Sandlund 2005
3873:10.3171/2017.6.FOCUS17257
3821:10.3171/2017.6.FOCUS17257
3512:Sargant & Slater 1963
2278:Ford & Henderson 2006
1451:cerebral ventriculography
1379:electroconvulsive therapy
1107:, sister of US president
1015:electroconvulsive therapy
325:electroconvulsive therapy
144:is a discredited form of
133: 'lobe' and
105:
91:
79:
63:
55:
35:
30:
6798:Neurosurgical procedures
6018:10.1177/0957154X05052224
5247:10.1177/0957154X07087345
5192:Kolin, Philip.
5082:. 2011;30(2):8.
4754:10.1076/jhin.8.1.60.1766
3412:Gross & Schäfer 2011
3396:Gross & Schäfer 2011
3313:Gross & Schäfer 2011
3239:Gross & Schäfer 2011
3203:Gross & Schäfer 2011
3110:Gross & Schäfer 2011
3081:Gross & Schäfer 2011
2946:Freeman & Watts 1944
2234:Gross & Schäfer 2011
2088:Gross & Schäfer 2011
1871:: 302–04. Archived from
1781:Kalat, James W. (2007).
1691:Johnson, Jenell (2014).
1329:
6558:Amygdalohippocampectomy
6026:USSR Ministry of Health
5826:10.4414/sanp.2010.02153
5695:Encyclopedia of Emotion
5554:10.1080/096470490897692
5540:Ogren, K.; Sandlund, M.
5338:Maisel, Albert Q..
5205:Kondratev, Fedor .
5003:British Medical Journal
4500:Bianchi, Leonardo.
1427:, which ushered in the
951:Freeman-Watts technique
636:catatonic schizophrenic
351:The Swiss psychiatrist
146:neurosurgical treatment
140: 'cut, slice') or
16:Neurosurgical operation
6717:Electroencephalography
6686:Magnetoencephalography
6360:central nervous system
6302:Ten Notable Lobotomies
6287:article on cingulotomy
6252:Sutherland, John.
6243: Nobel Media.
5420:Brain Research Reviews
5262:Kragh, J.V..
5166:10.1006/brln.1993.1061
4940:10.1192/bjp.90.379.532
4782:. 1992;359(2):364.
4603:. 1932;13:259–351.
4162:Szasz, Thomas (2011).
4018:Diefenbach et al. 1999
1062:
920:
821:
695:
675:
544:
493:
459:
417:
356:
291:
6803:Portuguese inventions
6793:Medical controversies
6662:Pneumoencephalography
6503:Bilateral cingulotomy
6468:Suboccipital puncture
6060:Valenstein, Elliot A.
6038:Valenstein, Elliot S.
6005:History of Psychiatry
5908:10.1176/ajp.152.4.505
5574:Pre-frontal leucotomy
5396:Martin, Douglas.
5351:. 2008;25(1):1–4.
5238:History of Psychiatry
5184:Saturday Evening Post
5134:. 2006;59(4):727.
5109:History of Psychiatry
4994:Goldbeck-Wood, Sandra
4974:Медицинский работник
4618:History of Psychiatry
4472:History of Psychiatry
2244:, pp. 572, 575;
1894:Noyes & Kolb 1962
1822:10.1353/bhm.2017.0002
1784:Biological psychology
1731:Wonders & Marvels
1308:Frontal lobe disorder
1293:Bilateral cingulotomy
1182:Suddenly, Last Summer
1057:
972:psychiatric hospitals
961:Transorbital lobotomy
918:
816:
690:
670:
628:Julius Wagner-Jauregg
604:Roy Glenwood Spurling
535:
488:
454:
423:epileptic convulsions
411:
350:
317:insulin shock therapy
284:Insulin shock therapy
282:
189:psychiatric illnesses
185:psychiatric disorders
154:neurological disorder
42:Lobotomy underway at
6671:Transcranial Doppler
6657:Cerebral angiography
6609:Spinal decompression
6153:Suddenly Last Summer
6008:. 2005 [
5986:. 1996 [
5898:. 1995 [
5642:. 1937;100:3–16.
5422:. 2005 [
5315:Acta Neurochirurgica
5226:. 2005 [
4982:Gilyarovsky, Vasily
4970:Gilyarovsky, Vasily
4744:. 1999 [
4621:. 2000 [
4597:Brickner, Richard M.
4475:. 1997 [
4138:Wood & Wood 2008
3510:, pp. 486 n.1;
2242:Joanette et al. 1993
2149:, pp. 190–225;
1516:It was estimated by
1438:cerebral angiography
1263:medical photographer
1208:1975 film adaptation
1167:Robert Penn Warren's
1133:American playwright
953:, also known as the
755:, and one each with
709:cerebral angiography
383:), and an output or
297:therapeutic nihilism
150:psychiatric disorder
59:Leucotomy, leukotomy
6667:Echoencephalography
6433:Thalamic stimulator
6148:Williams, Tennessee
5511:Noll, Richard.
5356:Macmillan, M..
5080:Neurosurgical Focus
4723:Shame of the States
3860:Neurosurgical Focus
3808:Neurosurgical Focus
3554:, pp. 477, 487
3542:, pp. 477, 486
2399:Manjila et al. 2008
2250:Manjila et al. 2008
2224:, pp. 116, 129
2168:, pp. 600–05;
1613:Nobelprize.org 2013
1425:coup d'état of 1926
1313:Frontal lobe injury
842:, and one close to
361:Gottlieb Burckhardt
353:Gottlieb Burckhardt
343:Early psychosurgery
254:emotionally blunted
6752:Glasgow Coma Scale
6520:Corpus callosotomy
6449:Ventricular system
6229:; 29 October 1998.
6196:Wright, Frank Leon
5662:10.1093/shm/hkp061
5640:G Accad Med Torino
5570:Partridge, Maurice
5488:World Neurosurgery
5449:Convulsive Therapy
5403:The New York Times
5349:Neurosurgery Focus
5323:10.1007/BF01401819
5158:Brain and Language
4355:, pp. 72–75;
3943:Goldbeck-Wood 1996
3781:www.britannica.com
3237:, pp. 80–81;
3189:, pp. 80–81;
2794:, pp. 48–55;
2716:Heller et al. 2006
2685:Heller et al. 2006
2673:Heller et al. 2006
2667:, pp. 72–73;
2588:, pp. 22–23;
2268:, pp. 79–92;
2264:, pp. 85–89;
2238:Heller et al. 2006
2137:, pp. 371–82.
2102:, pp. 505–15;
2063:, pp. 148–49.
1940:, pp. 499–516
1923:, pp. 143–54.
1875:on 7 February 2019
1756:Western University
1342:Walter Rudolf Hess
1172:All the King's Men
1135:Tennessee Williams
999:Walter Rudolf Hess
921:
911:American leucotomy
773:bowel incontinence
728:association tracts
698:—Egas Moniz (1937)
658:conditioned reflex
643:Neurological model
600:blunting of affect
545:
509:António Egas Moniz
494:
491:António Egas Moniz
446:Vladimir Bekhterev
418:
381:association center
357:
313:deep sleep therapy
292:
196:António Egas Moniz
6775:
6774:
6573:
6572:
6283:Lobotomy's back:
6188:978-1-57224-568-6
6162:978-0-8222-1094-8
6122:. p. 275–304.
6120:978-0-86377-395-2
6098:978-1-59385-329-7
6076:. p. 499–516.
6074:978-1-879284-17-3
6052:978-0-444-81124-0
5944:Tierney, Ann Jane
5878:978-1-60918-072-0
5792:978-0-442-20252-1
5726:978-3-211-33081-4
5704:978-0-313-34576-0
5618:Porter, Roy.
5603:Prior, Alex.
5582:Pressman, Jack D.
5523:978-0-8160-6405-2
5476:978-0-89042-275-5
5464:Moniz, Egas.
5389:978-3-8376-1433-6
5342:. 6 May 1946.
5303:978-0-19-506284-7
5042:978-0-19-959125-1
4962:978-0-88048-964-5
4906:Freberg, Laura A.
4898:978-0-19-856721-9
4876:978-0-19-514694-3
4670:978-1-58046-412-3
4545:978-0-7627-3427-6
4533:Bragg, Lynn.
4526:978-0-521-27717-4
4359:, pp. 241–42
4331:, pp. 119–20
4175:978-1-4128-0895-8
3945:, pp. 708–09
3933:, pp. 353–67
3897:, pp. 227–28
3526:, pp. 476–77
3457:, pp. 482–83
3323:, pp. 237–39
2810:, pp. 51, 55
2413:, pp. 77–101
2334:, pp. 69, 77
2286:Sakas et al. 2007
2282:Green et al. 2010
2172:, pp. 89, 93
2034:, pp. 148–50
1987:, pp. 101–13
1964:, pp. 416–17
1952:, pp. 151–72
1908:, pp. 470–71
1896:, pp. 550–55
1865:BCMedical Journal
1429:Ditadura Nacional
1421:Versailles Treaty
1284:Psychiatry portal
936:neuropathological
824:—Amarro Fiamberti
812:Italian leucotomy
686:First leucotomies
180:, to be severed.
166:prefrontal cortex
116:
115:
6810:
6701:Microneurography
6587:Meningeal biopsy
6486:
6451:
6421:
6410:
6409:
6348:
6341:
6334:
6325:
6324:
6274:Mental Cruelty:
6257:
6248:
6239:
6230:
6221:
6205:
6197:
6191:
6182:; 2008.
6171:
6165:
6149:
6143:
6129:
6123:
6107:
6101:
6100:. p. 505–17.
6083:
6077:
6061:
6055:
6054:. p. 539–54.
6039:
6033:
6027:
6021:
5997:
5991:
5975:
5969:
5945:
5939:
5925:
5919:
5887:
5881:
5865:
5859:
5835:
5829:
5815:
5809:
5801:
5795:
5779:
5773:
5757:
5751:
5735:
5729:
5728:. p. 365–74.
5713:
5707:
5691:
5685:
5671:
5665:
5649:
5643:
5637:
5631:
5614:
5599:
5583:
5577:
5571:
5565:
5541:
5535:
5526:
5507:
5485:
5479:
5478:. p. 237–39.
5460:
5443:
5413:
5407:
5392:
5373:
5364:; 2000.
5352:
5343:
5334:
5312:
5311:Lichterman, B.L.
5306:
5287:
5258:
5231:
5212:
5201:
5188:
5177:
5152:
5135:
5127:
5121:
5105:
5099:
5077:
5071:
5051:
5045:
5029:
5023:
4995:
4989:
4983:
4977:
4971:
4965:
4949:
4943:
4927:
4921:
4907:
4901:
4885:
4879:
4863:
4857:
4833:
4827:
4811:
4805:
4789:
4783:
4771:
4765:
4733:
4727:
4719:
4713:
4705:Federal Register
4697:
4689:
4679:
4673:
4672:. p. 215–22.
4657:
4651:
4634:
4610:
4609:Brown, Edward M.
4604:
4598:
4592:
4576:
4575:Braslow, Joel T.
4570:
4554:
4553:Braslow, Joel T.
4548:
4529:
4513:
4507:
4496:
4461:
4452:
4438:
4432:
4406:
4405:
4403:
4401:
4389:
4383:
4382:
4380:
4378:
4366:
4360:
4350:
4344:
4338:
4332:
4326:
4320:
4314:
4308:
4302:
4296:
4295:, pp. 42–44
4290:
4279:
4273:
4267:
4262:, p. 250,
4258:Macmillan (
4256:
4250:
4249:, pp. 50–51
4244:
4238:
4232:
4226:
4221:
4215:
4210:
4204:
4198:
4192:
4186:
4180:
4179:
4159:
4153:
4147:
4141:
4135:
4129:
4126:Gilyarovsky 1973
4123:
4117:
4116:, pp. 17–18
4112:, pp. 1–4;
4107:
4101:
4099:Gilyarovsky 1950
4096:
4090:
4084:
4078:
4072:
4066:
4064:
4063:on 20 July 2011.
4062:
4051:
4043:
4037:
4027:
4021:
4020:, pp. 60–69
4015:
4006:
4005:, pp. 17–18
4000:
3994:
3988:
3982:
3981:
3979:
3977:
3971:
3965:. Archived from
3964:
3952:
3946:
3940:
3934:
3928:
3922:
3916:
3910:
3904:
3898:
3892:
3886:
3885:
3875:
3851:
3845:
3840:
3834:
3833:
3823:
3799:
3793:
3792:
3790:
3788:
3773:
3767:
3761:
3752:
3746:
3740:
3734:
3728:
3722:
3713:
3707:
3696:
3689:
3683:
3682:, pp. 73–75
3677:
3671:
3665:
3659:
3649:
3643:
3633:
3624:
3614:
3608:
3594:
3585:
3579:
3570:
3564:
3555:
3549:
3543:
3533:
3527:
3521:
3515:
3505:
3499:
3492:
3486:
3476:
3470:
3464:
3458:
3452:
3446:
3439:
3430:
3424:
3415:
3405:
3399:
3393:
3384:
3374:
3368:
3362:
3356:
3350:
3344:
3330:
3324:
3306:
3300:
3294:
3283:
3277:
3266:
3260:
3254:
3248:
3242:
3228:
3222:
3216:
3210:
3200:
3194:
3184:
3178:
3172:
3163:
3157:
3151:
3145:
3139:
3132:
3126:
3119:
3113:
3103:
3097:
3090:
3084:
3078:
3072:
3065:
3059:
3045:
3039:
3025:
3019:
3012:
3006:
3000:
2991:
2985:
2976:
2970:
2961:
2955:
2949:
2942:
2936:
2930:
2915:
2908:
2899:
2893:
2884:
2879:
2873:
2863:
2854:
2840:
2834:
2828:
2811:
2805:
2799:
2789:
2783:
2782:, pp. 72–73
2777:
2771:
2765:
2759:
2758:, pp. 48–50
2753:
2747:
2741:
2735:
2725:
2719:
2709:
2703:
2697:
2688:
2682:
2676:
2658:
2652:
2646:
2637:
2631:
2625:
2615:
2609:
2599:
2593:
2579:
2573:
2567:
2561:
2555:
2536:
2530:
2524:
2519:
2513:
2507:
2494:
2480:
2474:
2468:
2462:
2455:
2449:
2439:
2430:
2420:
2414:
2408:
2402:
2396:
2390:
2384:
2378:
2372:
2366:
2356:
2350:
2344:
2335:
2329:
2323:
2317:
2308:
2302:
2293:
2231:
2225:
2215:
2209:
2203:
2197:
2191:
2185:
2179:
2173:
2159:
2153:
2144:
2138:
2132:
2126:
2120:
2111:
2097:
2091:
2085:
2076:
2070:
2064:
2058:
2052:
2041:
2035:
2013:
2007:
1997:
1988:
1982:
1976:
1971:
1965:
1959:
1953:
1947:
1941:
1935:
1924:
1918:
1909:
1903:
1897:
1891:
1885:
1884:
1882:
1880:
1856:
1850:
1849:
1805:
1799:
1798:
1778:
1772:
1771:
1769:
1767:
1762:on 14 March 2016
1758:. Archived from
1748:
1742:
1741:
1739:
1737:
1722:
1716:
1715:
1713:
1711:
1688:
1682:
1681:
1679:
1677:
1662:
1653:
1652:
1640:
1634:
1629:
1616:
1610:
1604:
1598:
1589:
1588:
1586:
1584:
1570:
1554:
1550:
1544:
1540:
1534:
1531:
1525:
1514:
1508:
1505:
1499:
1496:
1490:
1486:
1480:
1477:
1471:
1462:The patient had
1460:
1454:
1447:
1441:
1416:
1410:
1406:
1400:
1397:
1391:
1388:
1382:
1368:
1362:
1351:
1345:
1339:
1286:
1281:
1280:
1248:depicts actress
1105:Rosemary Kennedy
1087:Nobel Foundation
1084:
1067:
1046:, the author of
979:Amarro Fiamberti
905:Walter Freeman's
888:Amarro Fiamberti
825:
765:manic-depression
699:
608:Spafford Ackerly
588:Leonardo Bianchi
539:animation: left
442:Saint Petersburg
395:mental pathology
337:patients' rights
305:malarial therapy
286:administered in
250:mental disorders
109:edit on Wikidata
101:
75:
74:
40:
28:
27:
6818:
6817:
6813:
6812:
6811:
6809:
6808:
6807:
6778:
6777:
6776:
6771:
6738:
6734:Polysomnography
6722:Lumbar puncture
6705:
6633:
6591:
6569:
6541:Pituitary gland
6529:
6515:Hemispherectomy
6482:
6477:
6463:Ventriculostomy
6447:
6442:
6419:globus pallidus
6413:
6399:
6371:
6362:
6352:
6313:The Lobotomists
6265:
6260:
6195:
6169:
6147:
6128:Wiener, Norbert
6127:
6105:
6081:
6059:
6037:
6025:
5995:
5973:
5943:
5923:
5885:
5863:
5834:Stone, James L.
5833:
5813:
5799:
5777:
5755:
5734:Shorter, Edward
5733:
5711:
5689:
5669:
5647:
5635:
5610:The Independent
5581:
5569:
5539:
5483:
5411:
5310:
5268:Medical History
5125:
5103:
5075:
5050:Grenander, M.E.
5049:
5027:
4993:
4981:
4969:
4947:
4925:
4905:
4883:
4862:Finger, Stanley
4861:
4831:
4810:Feldman, Burton
4809:
4787:
4769:
4731:
4718:Deutsch, Albert
4717:
4693:
4677:
4655:
4608:
4596:
4574:
4552:
4511:
4437:Arnold, William
4436:
4415:
4410:
4409:
4399:
4397:
4390:
4386:
4376:
4374:
4367:
4363:
4351:
4347:
4339:
4335:
4327:
4323:
4315:
4311:
4303:
4299:
4291:
4282:
4274:
4270:
4257:
4253:
4245:
4241:
4233:
4229:
4222:
4218:
4211:
4207:
4199:
4195:
4187:
4183:
4176:
4160:
4156:
4148:
4144:
4136:
4132:
4124:
4120:
4110:Lichterman 1993
4108:
4104:
4097:
4093:
4085:
4081:
4073:
4069:
4060:
4049:
4045:
4044:
4040:
4028:
4024:
4016:
4009:
4001:
3997:
3991:Lichterman 1993
3989:
3985:
3975:
3973:
3972:on 5 March 2016
3969:
3962:
3954:
3953:
3949:
3941:
3937:
3929:
3925:
3921:, pp. 1–20
3917:
3913:
3905:
3901:
3893:
3889:
3852:
3848:
3841:
3837:
3800:
3796:
3786:
3784:
3775:
3774:
3770:
3762:
3755:
3747:
3743:
3735:
3731:
3723:
3716:
3708:
3699:
3690:
3686:
3678:
3674:
3666:
3662:
3650:
3646:
3634:
3627:
3619:, p. 227;
3615:
3611:
3603:, p. 293;
3599:, p. 182;
3595:
3588:
3580:
3573:
3565:
3558:
3550:
3546:
3534:
3530:
3522:
3518:
3506:
3502:
3493:
3489:
3481:, p. 652;
3477:
3473:
3465:
3461:
3453:
3449:
3440:
3433:
3425:
3418:
3406:
3402:
3394:
3387:
3375:
3371:
3363:
3359:
3351:
3347:
3341:Valenstein 1997
3339:, p. 651;
3331:
3327:
3307:
3303:
3295:
3286:
3278:
3269:
3261:
3257:
3249:
3245:
3229:
3225:
3217:
3213:
3201:
3197:
3185:
3181:
3173:
3166:
3158:
3154:
3146:
3142:
3133:
3129:
3120:
3116:
3104:
3100:
3091:
3087:
3079:
3075:
3069:Valenstein 1997
3066:
3062:
3056:Valenstein 1997
3054:, p. 541;
3052:Valenstein 1990
3046:
3042:
3034:, p. 650;
3030:, p. 541;
3028:Valenstein 1990
3026:
3022:
3016:Valenstein 1990
3013:
3009:
3001:
2994:
2988:Valenstein 1997
2986:
2979:
2973:Valenstein 1990
2971:
2964:
2956:
2952:
2943:
2939:
2931:
2918:
2909:
2902:
2894:
2887:
2880:
2876:
2864:
2857:
2841:
2837:
2829:
2814:
2806:
2802:
2796:Valenstein 1997
2790:
2786:
2778:
2774:
2766:
2762:
2754:
2750:
2742:
2738:
2726:
2722:
2710:
2706:
2698:
2691:
2683:
2679:
2671:, p. 226;
2659:
2655:
2647:
2640:
2632:
2628:
2616:
2612:
2604:, p. 226;
2600:
2596:
2580:
2576:
2568:
2564:
2556:
2539:
2531:
2527:
2520:
2516:
2508:
2497:
2489:, p. 486;
2481:
2477:
2469:
2465:
2456:
2452:
2440:
2433:
2421:
2417:
2409:
2405:
2397:
2393:
2385:
2381:
2373:
2369:
2361:, p. 276;
2357:
2353:
2345:
2338:
2330:
2326:
2318:
2311:
2303:
2296:
2288:, p. 366;
2284:, p. 208;
2280:, p. 219;
2276:, p. 138;
2260:, p. 485;
2256:, p. 326;
2248:, p. 486;
2240:, p. 727;
2232:
2228:
2220:, p. 428;
2216:
2212:
2204:
2200:
2192:
2188:
2180:
2176:
2164:, p. 404;
2160:
2156:
2145:
2141:
2133:
2129:
2121:
2114:
2106:, p. 337;
2098:
2094:
2086:
2079:
2071:
2067:
2059:
2055:
2042:
2038:
2030:, p. 650;
2014:
2010:
2002:, p. 650;
1998:
1991:
1983:
1979:
1972:
1968:
1960:
1956:
1948:
1944:
1938:Valenstein 1997
1936:
1927:
1919:
1912:
1904:
1900:
1892:
1888:
1878:
1876:
1857:
1853:
1806:
1802:
1795:
1779:
1775:
1765:
1763:
1750:
1749:
1745:
1735:
1733:
1723:
1719:
1709:
1707:
1705:
1689:
1685:
1675:
1673:
1663:
1656:
1641:
1637:
1632:Sutherland 2004
1630:
1619:
1611:
1607:
1599:
1592:
1582:
1580:
1572:
1571:
1567:
1562:
1557:
1551:
1547:
1541:
1537:
1532:
1528:
1518:William Sargant
1515:
1511:
1506:
1502:
1497:
1493:
1487:
1483:
1478:
1474:
1461:
1457:
1448:
1444:
1417:
1413:
1407:
1403:
1398:
1394:
1389:
1385:
1369:
1365:
1352:
1348:
1340:
1336:
1332:
1327:
1282:
1275:
1272:
1159:
1109:John F. Kennedy
1101:
1095:
1082:
1065:
1033:
1024:
963:
913:
827:
823:
814:
806:brain abscesses
804:, epilepsy and
797:
701:
697:
688:
645:
568:mammalian brain
517:
483:
431:sensory aphasia
403:mental distress
377:afferent system
369:cerebral cortex
345:
277:
231:
112:
97:
70:
69:
51:
24:
17:
12:
11:
5:
6816:
6806:
6805:
6800:
6795:
6790:
6773:
6772:
6770:
6769:
6764:
6759:
6754:
6748:
6746:
6740:
6739:
6737:
6736:
6731:
6730:
6729:
6719:
6713:
6711:
6707:
6706:
6704:
6703:
6698:
6693:
6688:
6683:
6678:
6673:
6664:
6659:
6654:
6649:
6643:
6641:
6635:
6634:
6632:
6631:
6626:
6621:
6616:
6611:
6605:
6603:
6593:
6592:
6590:
6589:
6583:
6581:
6575:
6574:
6571:
6570:
6568:
6567:
6562:
6561:
6560:
6550:
6549:
6548:
6546:Hypophysectomy
6537:
6535:
6531:
6530:
6528:
6527:
6522:
6517:
6512:
6507:
6506:
6505:
6500:
6489:
6487:
6479:
6478:
6476:
6475:
6470:
6465:
6460:
6458:Cerebral shunt
6454:
6452:
6444:
6443:
6441:
6440:
6435:
6430:
6424:
6422:
6407:
6401:
6400:
6398:
6397:
6392:
6387:
6381:
6379:
6373:
6372:
6367:
6364:
6363:
6358:involving the
6351:
6350:
6343:
6336:
6328:
6322:
6321:
6309:
6304:
6299:
6294:
6289:
6280:
6271:
6264:
6263:External links
6261:
6259:
6258:
6249:
6240:
6231:
6222:
6210:Online sources
6207:
6206:
6192:
6166:
6144:
6124:
6102:
6078:
6056:
6034:
6022:
5992:
5970:
5940:
5920:
5882:
5860:
5830:
5810:
5796:
5774:
5752:
5730:
5708:
5686:
5666:
5644:
5632:
5615:
5600:
5578:
5566:
5536:
5527:
5508:
5480:
5461:
5444:
5408:
5393:
5374:
5353:
5344:
5335:
5307:
5288:
5259:
5232:
5213:
5202:
5189:
5178:
5153:
5136:
5122:
5100:
5072:
5046:
5024:
4990:
4978:
4966:
4944:
4922:
4902:
4880:
4858:
4828:
4806:
4784:
4766:
4728:
4714:
4690:
4678:Day, Elizabeth
4674:
4652:
4635:
4605:
4593:
4571:
4549:
4530:
4512:Bigsby, C.W.E.
4508:
4497:
4462:
4453:
4433:
4416:
4414:
4411:
4408:
4407:
4384:
4361:
4345:
4333:
4321:
4309:
4297:
4293:Grenander 1978
4280:
4276:Nijensohn 2012
4268:
4251:
4239:
4227:
4216:
4205:
4193:
4181:
4174:
4154:
4142:
4140:, p. 153.
4130:
4118:
4102:
4091:
4089:, p. 148.
4079:
4067:
4038:
4022:
4007:
3995:
3993:, pp. 1–4
3983:
3947:
3935:
3923:
3911:
3899:
3887:
3846:
3835:
3794:
3783:. 19 July 2024
3768:
3753:
3751:, p. 184.
3741:
3729:
3714:
3697:
3684:
3672:
3660:
3654:, p. 76;
3644:
3638:, p. 76;
3625:
3609:
3586:
3571:
3556:
3544:
3528:
3516:
3500:
3487:
3471:
3459:
3447:
3431:
3416:
3410:, p. 74;
3400:
3385:
3379:, p. 75;
3369:
3357:
3345:
3335:, p. 81;
3325:
3301:
3284:
3267:
3265:, p. 292.
3255:
3243:
3233:, p. 29;
3223:
3211:
3195:
3179:
3177:, p. 237.
3164:
3152:
3140:
3127:
3114:
3108:, p. 99;
3098:
3085:
3073:
3060:
3050:, p. 77;
3040:
3020:
3007:
2992:
2977:
2962:
2950:
2937:
2916:
2900:
2885:
2874:
2868:, p. 52;
2855:
2849:, p. 51;
2835:
2812:
2800:
2784:
2772:
2760:
2748:
2736:
2730:, p. 48;
2720:
2714:, p. 48;
2704:
2689:
2677:
2653:
2638:
2626:
2610:
2594:
2584:, p. 25;
2574:
2562:
2537:
2525:
2514:
2495:
2485:, p. 80;
2475:
2463:
2450:
2444:, p. 80;
2431:
2415:
2403:
2391:
2379:
2367:
2351:
2336:
2324:
2309:
2294:
2272:, p. 37;
2226:
2210:
2208:, p. 520.
2198:
2186:
2174:
2154:
2139:
2127:
2112:
2092:
2077:
2075:, p. 218.
2065:
2053:
2036:
2008:
1989:
1977:
1966:
1954:
1942:
1925:
1910:
1906:Partridge 1950
1898:
1886:
1851:
1800:
1793:
1773:
1743:
1717:
1704:978-0472119448
1703:
1683:
1654:
1635:
1617:
1605:
1590:
1564:
1563:
1561:
1558:
1556:
1555:
1545:
1535:
1526:
1509:
1500:
1491:
1481:
1472:
1455:
1442:
1411:
1409:was warranted.
1401:
1392:
1383:
1363:
1346:
1333:
1331:
1328:
1326:
1325:
1320:
1315:
1310:
1305:
1303:medical ethics
1296:
1289:
1288:
1287:
1271:
1268:
1267:
1266:
1255:The 2018 film
1253:
1250:Frances Farmer
1236:
1232:A Fine Madness
1224:
1217:'s 1963 novel
1211:
1200:'s 1962 novel
1194:
1193:her, Doctor?".
1177:
1158:
1155:
1154:
1153:
1146:
1138:
1131:
1128:Sigrid Hjertén
1124:
1118:
1112:
1094:
1091:
1079:Torsten Wiesel
1044:Norbert Wiener
1032:
1029:
1023:
1020:
962:
959:
932:James W. Watts
928:Walter Freeman
912:
909:
880:Ludvig Puusepp
815:
813:
810:
796:
793:
753:panic disorder
689:
687:
684:
666:associationism
644:
641:
577:focal epilepsy
516:
513:
482:
479:
471:parietal lobes
450:Ludvig Puusepp
414:Ludvig Puusepp
373:associationist
344:
341:
276:
273:
268:Walter Freeman
230:
227:
211:United Kingdom
114:
113:
106:
103:
102:
95:
89:
88:
83:
77:
76:
67:
61:
60:
57:
53:
52:
44:Södersjukhuset
41:
33:
32:
15:
9:
6:
4:
3:
2:
6815:
6804:
6801:
6799:
6796:
6794:
6791:
6789:
6786:
6785:
6783:
6768:
6765:
6763:
6760:
6758:
6755:
6753:
6750:
6749:
6747:
6745:
6741:
6735:
6732:
6728:
6725:
6724:
6723:
6720:
6718:
6715:
6714:
6712:
6708:
6702:
6699:
6697:
6694:
6692:
6689:
6687:
6684:
6682:
6679:
6677:
6674:
6672:
6668:
6665:
6663:
6660:
6658:
6655:
6653:
6650:
6648:
6645:
6644:
6642:
6640:
6636:
6630:
6627:
6625:
6622:
6620:
6617:
6615:
6612:
6610:
6607:
6606:
6604:
6602:
6598:
6594:
6588:
6585:
6584:
6582:
6580:
6576:
6566:
6563:
6559:
6556:
6555:
6554:
6551:
6547:
6544:
6543:
6542:
6539:
6538:
6536:
6532:
6526:
6523:
6521:
6518:
6516:
6513:
6511:
6508:
6504:
6501:
6499:
6496:
6495:
6494:
6493:Psychosurgery
6491:
6490:
6488:
6485:
6480:
6474:
6471:
6469:
6466:
6464:
6461:
6459:
6456:
6455:
6453:
6450:
6445:
6439:
6436:
6434:
6431:
6429:
6426:
6425:
6423:
6420:
6416:
6411:
6408:
6406:
6402:
6396:
6393:
6391:
6388:
6386:
6383:
6382:
6380:
6378:
6374:
6370:
6365:
6361:
6357:
6349:
6344:
6342:
6337:
6335:
6330:
6329:
6326:
6319:
6315:
6314:
6310:
6308:
6305:
6303:
6300:
6298:
6295:
6293:
6290:
6288:
6286:
6281:
6279:
6277:
6272:
6270:
6267:
6266:
6255:
6250:
6246:
6241:
6237:
6232:
6228:
6223:
6219:
6214:
6213:
6212:
6211:
6203:
6202:
6193:
6189:
6185:
6181:
6177:
6176:
6167:
6163:
6159:
6155:
6154:
6145:
6141:
6140:0-262-73009-X
6137:
6133:
6125:
6121:
6117:
6113:
6112:
6103:
6099:
6095:
6091:
6087:
6079:
6075:
6071:
6067:
6066:
6057:
6053:
6049:
6045:
6044:
6035:
6031:
6023:
6019:
6015:
6011:
6007:
6006:
6001:
5993:
5989:
5985:
5984:
5979:
5971:
5967:
5963:
5959:
5955:
5951:
5950:
5941:
5937:
5936:0-7658-0379-8
5933:
5929:
5924:Szasz, Thomas
5921:
5917:
5913:
5909:
5905:
5901:
5897:
5896:
5891:
5883:
5879:
5875:
5871:
5870:
5861:
5857:
5853:
5849:
5845:
5841:
5840:
5831:
5827:
5823:
5819:
5811:
5807:
5806:
5797:
5793:
5789:
5785:
5784:
5778:Shutts, David
5775:
5771:
5770:1-4685-4962-6
5767:
5763:
5762:
5753:
5749:
5748:0-471-24531-3
5745:
5741:
5740:
5731:
5727:
5723:
5719:
5718:
5709:
5705:
5701:
5697:
5696:
5687:
5683:
5682:9781580464499
5679:
5675:
5667:
5663:
5659:
5655:
5654:
5645:
5641:
5633:
5629:
5628:0-00-637454-9
5625:
5621:
5616:
5612:
5611:
5606:
5601:
5597:
5596:0-521-52459-8
5593:
5589:
5588:
5579:
5575:
5567:
5563:
5559:
5555:
5551:
5547:
5546:
5537:
5533:
5528:
5524:
5520:
5516:
5515:
5509:
5505:
5501:
5497:
5493:
5489:
5484:Nijensohn, DE
5481:
5477:
5473:
5469:
5468:
5462:
5458:
5454:
5450:
5445:
5441:
5437:
5433:
5429:
5425:
5421:
5417:
5409:
5405:
5404:
5399:
5394:
5390:
5386:
5382:
5381:
5375:
5371:
5370:0-262-13363-6
5367:
5363:
5359:
5354:
5350:
5345:
5341:
5336:
5332:
5328:
5324:
5320:
5316:
5308:
5304:
5300:
5296:
5295:
5289:
5285:
5281:
5277:
5273:
5269:
5265:
5260:
5256:
5252:
5248:
5244:
5240:
5239:
5233:
5229:
5225:
5224:
5219:
5214:
5210:
5209:
5203:
5199:
5195:
5190:
5186:
5185:
5179:
5175:
5171:
5167:
5163:
5159:
5154:
5150:
5149:0-485-24011-4
5146:
5142:
5137:
5133:
5132:
5123:
5119:
5115:
5111:
5110:
5101:
5097:
5093:
5089:
5085:
5081:
5073:
5069:
5065:
5061:
5060:
5055:
5047:
5043:
5039:
5035:
5034:
5025:
5021:
5017:
5013:
5009:
5005:
5004:
4999:
4991:
4987:
4979:
4975:
4967:
4963:
4959:
4955:
4954:
4945:
4941:
4937:
4933:
4932:
4923:
4919:
4918:0-547-17779-8
4915:
4911:
4903:
4899:
4895:
4891:
4890:
4881:
4877:
4873:
4869:
4868:
4859:
4855:
4851:
4847:
4843:
4839:
4838:
4829:
4825:
4824:1-55970-592-2
4821:
4817:
4816:
4807:
4803:
4802:0-471-23292-0
4799:
4795:
4794:
4785:
4781:
4780:
4775:
4767:
4763:
4759:
4755:
4751:
4747:
4743:
4742:
4737:
4729:
4725:
4724:
4715:
4711:
4707:
4706:
4701:
4696:
4691:
4687:
4683:
4675:
4671:
4667:
4663:
4662:
4656:Cooter, Roger
4653:
4649:
4645:
4641:
4636:
4632:
4628:
4624:
4620:
4619:
4614:
4606:
4602:
4594:
4590:
4589:0-520-20547-2
4586:
4582:
4581:
4572:
4568:
4564:
4560:
4559:
4550:
4546:
4542:
4538:
4537:
4531:
4527:
4523:
4519:
4518:
4509:
4505:
4504:
4498:
4494:
4490:
4486:
4482:
4478:
4474:
4473:
4468:
4463:
4459:
4454:
4450:
4449:0-425-05481-0
4446:
4442:
4434:
4430:
4429:
4423:
4422:
4421:
4420:
4419:Print Sources
4395:
4388:
4372:
4365:
4358:
4354:
4349:
4342:
4337:
4330:
4325:
4318:
4317:Williams 1998
4313:
4307:, p. 100
4306:
4301:
4294:
4289:
4287:
4285:
4278:, p. 582
4277:
4272:
4265:
4261:
4255:
4248:
4243:
4236:
4231:
4225:
4220:
4214:
4209:
4203:, p. 271
4202:
4197:
4190:
4185:
4177:
4171:
4167:
4166:
4158:
4151:
4146:
4139:
4134:
4127:
4122:
4115:
4111:
4106:
4100:
4095:
4088:
4083:
4076:
4071:
4059:
4055:
4052:(in French).
4048:
4042:
4036:
4035:3-927408-82-4
4032:
4026:
4019:
4014:
4012:
4004:
3999:
3992:
3987:
3968:
3961:
3959:
3951:
3944:
3939:
3932:
3927:
3920:
3915:
3909:, p. 107
3908:
3903:
3896:
3891:
3883:
3879:
3874:
3869:
3865:
3861:
3857:
3850:
3844:
3839:
3831:
3827:
3822:
3817:
3813:
3809:
3805:
3798:
3782:
3778:
3772:
3765:
3760:
3758:
3750:
3745:
3739:, p. 293
3738:
3733:
3726:
3725:Pressman 2002
3721:
3719:
3711:
3710:Pressman 2002
3706:
3704:
3702:
3694:
3693:Pressman 2002
3688:
3681:
3680:Pressman 2002
3676:
3669:
3668:Pressman 2002
3664:
3657:
3656:Kotowicz 2005
3653:
3652:Pressman 2002
3648:
3642:, p. 649
3641:
3637:
3636:Pressman 2002
3632:
3630:
3622:
3621:Pressman 2002
3618:
3613:
3607:, p. 506
3606:
3602:
3598:
3593:
3591:
3584:, p. 182
3583:
3578:
3576:
3569:, p. 478
3568:
3567:Kotowicz 2008
3563:
3561:
3553:
3552:Kotowicz 2008
3548:
3541:
3540:Kotowicz 2008
3537:
3532:
3525:
3524:Kotowicz 2008
3520:
3513:
3509:
3508:Kotowicz 2008
3504:
3498:, p. 182
3497:
3491:
3484:
3483:Kotowicz 2005
3480:
3475:
3469:, p. 483
3468:
3467:Kotowicz 2008
3463:
3456:
3455:Kotowicz 2008
3451:
3445:, p. 482
3444:
3443:Kotowicz 2008
3438:
3436:
3429:, p. 482
3428:
3427:Kotowicz 2008
3423:
3421:
3413:
3409:
3404:
3397:
3392:
3390:
3382:
3381:Kotowicz 2005
3378:
3373:
3366:
3365:Kotowicz 2005
3361:
3354:
3349:
3343:, p. 504
3342:
3338:
3334:
3333:Kotowicz 2005
3329:
3322:
3318:
3315:, p. 2;
3314:
3310:
3305:
3299:, p. 651
3298:
3293:
3291:
3289:
3281:
3280:Kotowicz 2005
3276:
3274:
3272:
3264:
3259:
3252:
3251:Pressman 2002
3247:
3240:
3236:
3235:Kotowicz 2005
3232:
3227:
3220:
3215:
3209:, p. 482
3208:
3207:Kotowicz 2008
3205:, p. 2;
3204:
3199:
3193:, p. 650
3192:
3188:
3187:Kotowicz 2005
3183:
3176:
3171:
3169:
3161:
3160:Kotowicz 2005
3156:
3149:
3144:
3138:, p. 651
3137:
3131:
3124:
3123:Kotowicz 2005
3118:
3111:
3107:
3106:Kotowicz 2005
3102:
3095:
3089:
3082:
3077:
3071:, p. 503
3070:
3064:
3058:, p. 503
3057:
3053:
3049:
3044:
3038:, p. 478
3037:
3036:Kotowicz 2008
3033:
3029:
3024:
3018:, p. 541
3017:
3011:
3005:, p. 650
3004:
2999:
2997:
2990:, p. 503
2989:
2984:
2982:
2975:, p. 541
2974:
2969:
2967:
2959:
2958:Pressman 2002
2954:
2948:, p. 532
2947:
2941:
2934:
2933:Pressman 2002
2929:
2927:
2925:
2923:
2921:
2913:
2912:Pressman 2002
2907:
2905:
2897:
2896:Kotowicz 2005
2892:
2890:
2883:
2882:Brickner 1932
2878:
2871:
2870:Kotowicz 2005
2867:
2866:Pressman 2002
2862:
2860:
2852:
2848:
2847:Pressman 2002
2844:
2839:
2832:
2831:Pressman 2002
2827:
2825:
2823:
2821:
2819:
2817:
2809:
2808:Pressman 2002
2804:
2798:, p. 541
2797:
2793:
2792:Pressman 2002
2788:
2781:
2776:
2769:
2768:Pressman 2002
2764:
2757:
2756:Pressman 2002
2752:
2745:
2740:
2733:
2729:
2728:Pressman 2002
2724:
2718:, p. 721
2717:
2713:
2712:Pressman 2002
2708:
2702:, p. 48.
2701:
2700:Pressman 2002
2696:
2694:
2687:, p. 721
2686:
2681:
2675:, p. 721
2674:
2670:
2666:
2662:
2661:Pressman 2002
2657:
2650:
2645:
2643:
2636:, p. 100
2635:
2630:
2624:, pp. 25
2623:
2620:, p. 2;
2619:
2614:
2608:, pp. 25
2607:
2603:
2598:
2592:, pp. 78
2591:
2590:Kotowicz 2005
2587:
2583:
2578:
2571:
2566:
2560:, p. 477
2559:
2558:Kotowicz 2008
2554:
2552:
2550:
2548:
2546:
2544:
2542:
2535:, p. 486
2534:
2533:Kotowicz 2008
2529:
2523:
2518:
2512:, p. 649
2511:
2506:
2504:
2502:
2500:
2492:
2488:
2487:Kotowicz 2008
2484:
2483:Kotowicz 2005
2479:
2473:, p. 149
2472:
2467:
2460:
2454:
2448:, p. 486
2447:
2446:Kotowicz 2008
2443:
2442:Kotowicz 2005
2438:
2436:
2429:, p. 486
2428:
2427:Kotowicz 2008
2424:
2419:
2412:
2411:Kotowicz 2005
2407:
2400:
2395:
2388:
2383:
2377:, p. 80.
2376:
2371:
2364:
2360:
2355:
2348:
2343:
2341:
2333:
2328:
2321:
2316:
2314:
2306:
2301:
2299:
2292:, p. 276
2291:
2287:
2283:
2279:
2275:
2271:
2267:
2263:
2259:
2255:
2252:, p. 1;
2251:
2247:
2246:Kotowicz 2008
2243:
2239:
2236:, p. 1;
2235:
2230:
2223:
2219:
2218:Pressman 2002
2214:
2207:
2202:
2196:, p. 216
2195:
2190:
2183:
2178:
2171:
2167:
2163:
2158:
2152:
2148:
2143:
2136:
2131:
2125:, p. 200
2124:
2123:Pressman 2002
2119:
2117:
2109:
2105:
2101:
2096:
2089:
2084:
2082:
2074:
2069:
2062:
2061:Pressman 2002
2057:
2051:, p. 149
2050:
2049:Pressman 2002
2046:
2040:
2033:
2032:Pressman 2002
2029:
2025:
2021:
2017:
2012:
2006:, p. 411
2005:
2001:
1996:
1994:
1986:
1981:
1975:
1970:
1963:
1958:
1951:
1946:
1939:
1934:
1932:
1930:
1922:
1917:
1915:
1907:
1902:
1895:
1890:
1874:
1870:
1866:
1862:
1855:
1847:
1843:
1839:
1835:
1831:
1827:
1823:
1819:
1815:
1811:
1804:
1796:
1794:9780495090793
1790:
1786:
1785:
1777:
1761:
1757:
1753:
1747:
1732:
1728:
1721:
1706:
1700:
1696:
1695:
1687:
1672:
1668:
1661:
1659:
1650:
1646:
1639:
1633:
1628:
1626:
1624:
1622:
1614:
1609:
1603:, p. 116
1602:
1597:
1595:
1579:
1575:
1569:
1565:
1549:
1539:
1530:
1523:
1519:
1513:
1504:
1495:
1485:
1476:
1469:
1465:
1459:
1452:
1446:
1439:
1434:
1430:
1426:
1422:
1415:
1405:
1396:
1387:
1380:
1376:
1372:
1367:
1361:institutions.
1359:
1358:
1350:
1343:
1338:
1334:
1324:
1321:
1319:
1318:Psychosurgery
1316:
1314:
1311:
1309:
1306:
1304:
1300:
1297:
1294:
1291:
1290:
1285:
1279:
1274:
1264:
1260:
1259:
1254:
1251:
1247:
1246:
1241:
1237:
1234:
1233:
1228:
1227:Elliott Baker
1225:
1222:
1221:
1216:
1212:
1209:
1205:
1204:
1199:
1195:
1192:
1188:
1184:
1183:
1178:
1174:
1173:
1168:
1165:
1164:
1163:
1151:
1147:
1143:
1139:
1136:
1132:
1129:
1125:
1122:
1119:
1116:
1113:
1110:
1106:
1103:
1102:
1100:
1093:Notable cases
1090:
1088:
1080:
1076:
1074:
1069:
1061:
1056:
1053:
1051:
1050:
1045:
1040:
1039:
1028:
1019:
1016:
1013:unavailable,
1010:
1006:
1002:
1000:
994:
990:
988:
984:
980:
975:
973:
969:
958:
956:
952:
947:
945:
940:
937:
933:
929:
926:
917:
908:
906:
901:
897:
893:
889:
884:
881:
877:
873:
869:
865:
861:
857:
853:
849:
845:
841:
837:
831:
826:
820:
809:
807:
803:
792:
790:
786:
782:
778:
774:
770:
766:
762:
758:
754:
750:
749:schizophrenia
746:
740:
737:
734:; this was a
733:
729:
725:
722:
718:
714:
710:
706:
700:
694:
683:
681:
680:unfalsifiable
674:
669:
667:
663:
659:
655:
654:Ramón y Cajal
651:
650:neuron theory
640:
637:
633:
629:
625:
621:
615:
613:
609:
605:
601:
597:
592:
589:
585:
584:
578:
574:
569:
563:
560:
555:
551:
542:
538:
534:
530:
528:
523:
515:Frontal lobes
512:
510:
506:
505:psychosurgery
502:
499:
492:
487:
478:
476:
472:
468:
464:
458:
453:
451:
447:
443:
438:
436:
435:word deafness
432:
428:
424:
415:
410:
406:
404:
400:
399:temporal lobe
396:
391:
386:
382:
378:
374:
370:
366:
365:psychosurgery
362:
354:
349:
340:
338:
334:
328:
326:
322:
318:
314:
310:
306:
302:
298:
290:in the 1950s.
289:
285:
281:
272:
269:
265:
261:
257:
255:
251:
246:
244:
240:
236:
226:
224:
220:
216:
212:
208:
207:United States
203:
201:
198:, shared the
197:
192:
190:
186:
181:
179:
175:
174:frontal lobes
171:
167:
163:
159:
155:
151:
147:
143:
139:
135:
132:
128:
125:
121:
110:
104:
100:
96:
94:
90:
87:
84:
82:
78:
73:
72:psychosurgery
68:
66:
62:
58:
54:
49:
45:
39:
34:
29:
26:
22:
6767:CHADS2 score
6727:CSF tap test
6647:Neuroimaging
6601:spinal canal
6565:Brain biopsy
6497:
6395:Cranioplasty
6369:Neurosurgery
6312:
6284:
6276:Sunday Times
6275:
6209:
6208:
6199:
6173:
6151:
6131:
6109:
6089:
6063:
6041:
6029:
6003:
5981:
5974:Tranøy, Joar
5947:
5927:
5893:
5886:Swayze, V.W.
5867:
5837:
5817:
5803:
5781:
5759:
5737:
5715:
5693:
5673:
5651:
5639:
5619:
5608:
5585:
5573:
5543:
5531:
5512:
5487:
5465:
5448:
5419:
5401:
5378:
5357:
5348:
5314:
5292:
5267:
5236:
5221:
5206:
5197:
5182:
5157:
5140:
5131:Neurosurgery
5129:
5107:
5104:Healy, David
5079:
5057:
5031:
5001:
4985:
4973:
4951:
4929:
4909:
4887:
4865:
4837:Neurosurgery
4835:
4813:
4791:
4788:El-Hai, Jack
4777:
4739:
4721:
4703:
4686:The Guardian
4685:
4659:
4639:
4616:
4600:
4578:
4556:
4534:
4515:
4501:
4470:
4457:
4440:
4426:
4418:
4417:
4398:. Retrieved
4387:
4375:. Retrieved
4364:
4348:
4336:
4324:
4319:, p. 15
4312:
4300:
4271:
4254:
4242:
4237:, p. 52
4230:
4219:
4208:
4201:Feldman 2001
4196:
4189:Jansson 1998
4184:
4164:
4157:
4145:
4133:
4121:
4105:
4094:
4082:
4070:
4058:the original
4041:
4025:
3998:
3986:
3974:. Retrieved
3967:the original
3957:
3950:
3938:
3926:
3914:
3902:
3895:Shorter 1997
3890:
3863:
3859:
3849:
3838:
3811:
3807:
3797:
3785:. Retrieved
3780:
3771:
3744:
3732:
3727:, p. 77
3712:, p. 76
3695:, p. 76
3687:
3675:
3670:, p. 73
3663:
3658:, p. 94
3647:
3623:, p. 78
3617:Shorter 1997
3612:
3547:
3536:Puusepp 1937
3531:
3519:
3514:, p. 98
3503:
3490:
3485:, p. 81
3474:
3462:
3450:
3408:Berrios 1997
3403:
3383:, p. 92
3377:Berrios 1997
3372:
3367:, p. 92
3360:
3355:, p. 75
3353:Berrios 1997
3348:
3328:
3309:Jansson 1998
3304:
3282:, p. 81
3258:
3253:, p. 54
3246:
3231:Tierney 2000
3226:
3214:
3198:
3182:
3162:, p. 89
3155:
3150:, p. 74
3148:Berrios 1997
3143:
3130:
3125:, p. 88
3117:
3101:
3096:, p. 74
3094:Berrios 1997
3088:
3076:
3063:
3048:Berrios 1997
3043:
3023:
3010:
2960:, p. 53
2953:
2940:
2935:, p. 52
2914:, p. 52
2898:, p. 84
2877:
2872:, p. 84
2853:, p. 14
2843:Bianchi 1922
2838:
2833:, p. 51
2803:
2787:
2780:Berrios 1997
2775:
2770:, p. 50
2763:
2751:
2746:, p. 73
2744:Berrios 1997
2739:
2734:, p. 73
2732:Berrios 1997
2723:
2707:
2680:
2669:Shorter 1997
2665:Berrios 1997
2656:
2651:, p. 72
2649:Berrios 1997
2629:
2622:Tierney 2000
2613:
2606:Tierney 2000
2602:Shorter 1997
2597:
2586:Tierney 2000
2582:Tierney 2000
2577:
2572:, p. 23
2570:Tierney 2000
2565:
2528:
2522:Puusepp 1937
2517:
2493:, p. 71
2491:Berrios 1997
2478:
2466:
2461:, p. 71
2459:Berrios 1997
2453:
2418:
2406:
2394:
2389:, p. 70
2387:Berrios 1997
2382:
2370:
2365:, p. 69
2363:Berrios 1997
2354:
2349:, p. 26
2347:Tierney 2000
2332:Berrios 1997
2327:
2322:, p. 69
2320:Berrios 1997
2307:, p. 68
2305:Berrios 1997
2229:
2213:
2201:
2189:
2184:, p. 3.
2182:Braslow 1997
2177:
2170:Braslow 1997
2166:Braslow 1995
2157:
2151:Jansson 1998
2147:Shorter 1997
2142:
2130:
2110:, p. 53
2095:
2073:Shorter 1997
2068:
2056:
2044:
2039:
2024:Deutsch 1948
2011:
1980:
1969:
1962:Freberg 2010
1957:
1945:
1901:
1889:
1877:. Retrieved
1873:the original
1868:
1864:
1854:
1816:(1): 33–61.
1813:
1809:
1803:
1783:
1776:
1764:. Retrieved
1760:the original
1755:
1752:"Lobotomies"
1746:
1734:. Retrieved
1730:
1720:
1708:. Retrieved
1693:
1686:
1674:. Retrieved
1670:
1648:
1638:
1608:
1581:. Retrieved
1578:Live Science
1577:
1568:
1548:
1538:
1529:
1522:Eliot Slater
1512:
1503:
1494:
1484:
1475:
1458:
1445:
1414:
1404:
1395:
1386:
1371:Ugo Cerletti
1366:
1355:
1349:
1337:
1258:The Mountain
1256:
1243:
1230:
1220:The Bell Jar
1218:
1215:Sylvia Plath
1201:
1190:
1180:
1170:
1160:
1142:Phineas Gage
1121:Josef Hassid
1115:Howard Dully
1077:
1073:Jimmy Carter
1070:
1063:
1058:
1054:
1047:
1036:
1034:
1025:
1011:
1007:
1003:
995:
991:
976:
964:
954:
950:
948:
943:
941:
922:
885:
832:
828:
822:
819:doing that.
817:
798:
741:
724:white matter
702:
696:
691:
676:
671:
646:
624:Leo Davidoff
620:William Mayo
616:
612:Henri Claude
596:Walter Dandy
593:
581:
573:brain trauma
564:
559:neurosurgeon
550:Stanley Cobb
546:
541:frontal lobe
518:
504:
495:
465:between the
460:
457:out ...
455:
439:
419:
358:
329:
293:
266:
262:
258:
247:
232:
219:Soviet Union
204:
193:
182:
172:part of the
141:
137:
134:
130:
127:
119:
117:
25:
6691:Myelography
6597:Spinal cord
6553:Hippocampus
6438:Pallidotomy
6428:Thalamotomy
6318:BBC Radio 4
6132:Cybernetics
5998:.
5976:.
5888:.
5864:Suchy, Yana
5814:Steck, A.J.
5636:Puusepp, L.
5414:.
5052:.
4996:.
4772:.
4734:.
4698:.
4611:.
4396:. IndieWire
4357:El-Hai 2005
4341:Arnold 1982
4305:Bigsby 1985
4128:, p. 4
4087:Wiener 1948
3919:Tranøy 1996
3843:El-Hai 2005
3749:El-Hai 2005
3737:Finger 2001
3601:Finger 2001
3597:El-Hai 2005
3582:El-Hai 2005
3496:El-Hai 2005
3414:, p. 3
3398:, p. 3
3263:Finger 2001
3241:, p. 2
3221:, p. 2
3112:, p. 1
3083:, p. 1
2634:El-Hai 2005
2401:, p. 1
2206:Porter 1999
2194:Cooter 2012
2108:Meduna 1985
2104:Hoenig 1995
2100:Swayze 1995
2090:, p. 5
2020:Wright 1947
2016:Maisel 1946
1974:Shutts 1982
1921:Cooper 2014
1187:homosexuals
1169:1946 novel
925:neurologist
789:kleptomania
751:, two with
747:, six with
721:subcortical
662:Ivan Pavlov
583:Witzelsucht
527:chimpanzees
522:John Fulton
501:neurologist
481:Development
355:(1836–1907)
239:incontinent
56:Other names
6782:Categories
6710:Diagnostic
6614:Discectomy
6385:Craniotomy
6356:procedures
6354:Tests and
5670:Raz, Mical
5648:Raz, Mical
4441:Shadowland
4400:8 November
4377:8 November
4353:Bragg 2005
4247:Kolin 1998
4224:Prior 2008
3976:20 January
3764:Dully 2005
3691:Quoted in
3494:Quoted in
3441:Quoted in
3321:Moniz 1994
3175:Moniz 1994
3134:Quoted in
3121:Quoted in
3092:Quoted in
3067:Quoted in
3014:Quoted in
2944:Quoted in
2910:Quoted in
2457:Quoted in
2375:Stone 2001
2270:Suchy 2011
2266:Stone 2001
2262:Steck 2010
2162:Healy 2000
2135:Brown 2000
1950:Szasz 2007
1879:4 February
1464:meningioma
1433:Republican
1375:Lucio Bini
1097:See also:
1022:Prevalence
968:anesthesia
802:meningitis
745:depression
719:into the "
498:Portuguese
333:Roy Porter
162:depression
122:(from
50:, in 1949.
6696:Wada test
6681:Brain PET
6676:Brain MRI
6629:Rhizotomy
6624:Cordotomy
5362:MIT Press
4264:1999–2012
4150:DHEW 1977
3866:(3): E6.
3830:1092-0684
3814:(3): E6.
2618:Doby 1992
2254:Noll 2007
1830:1086-3176
1766:12 August
1736:12 August
1710:12 August
1560:Citations
1299:Bioethics
1238:The 1982
1198:Ken Kesey
1150:Eva Perón
1031:Criticism
900:leucotome
848:Racconigi
795:Reception
781:nystagmus
761:catatonia
732:leucotome
321:cardiazol
235:stuporous
142:leucotomy
65:Specialty
48:Stockholm
21:Lobectomy
6788:Lobotomy
6579:Meninges
6498:Lobotomy
6484:Cerebrum
6415:Thalamus
6285:Discover
6010:archived
5988:archived
5966:11232345
5900:archived
5856:11446267
5562:16338693
5504:22079825
5457:11940805
5440:15914249
5424:archived
5284:20592884
5255:19397090
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