290:
251:
228:
274:
31:
585:
578:
532:
Zatloukal, K; French, SW; Strumptner, C; Strnad, P; Harada, M; Toivola, DM; Cadrin, M; Omary, MB (2007). "From
Mallory to Mallory-Denk bodies: what, how and why?".
571:
353:"Formation and involution of Mallory bodies ("alcoholic hyalin") in murine and human liver revealed by immunofluorescence microscopy with antibodies to prekeratin"
250:
273:
227:
289:
195:, who first described the structures in 1911. A renaming as Mallory–Denk bodies was proposed in 2007 to honor the contribution of Austrian pathologist
196:
563:
132:
493:"In vitro production of Mallory bodies and intracellular hyaline bodies: The central role of sequestosome 1 / p62"
806:
17:
456:
Michel, RP; Limacher, JJ; Kimoff, RJ (January 1982). "Mallory bodies in scar adenocarcinoma of the lung".
1217:
143:(8%), among other conditions. However, it has also been reported in certain other unrelated conditions.
1191:
128:
409:"The Mallory body: morphological, clinical and experimental studies (Part 1 of a literature survey)"
1100:
299:
136:
1222:
1146:
726:
667:
208:
46:
610:
598:
86:
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884:
831:
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325:
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1105:
1058:
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960:
801:
672:
102:
8:
810:
736:
711:
124:
117:
109:
826:
593:
1161:
1053:
1008:
942:
937:
869:
860:
706:
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438:
192:
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469:
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1196:
1186:
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1131:
1063:
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754:
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473:
430:
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1151:
1073:
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721:
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640:
303:
212:
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30:
1136:
1126:
1068:
1003:
917:
357:
Proceedings of the
National Academy of Sciences of the United States of America
180:
140:
58:
491:
Stumptner, Conny; Fuchsbichler, Andrea; Zatloukal, Kurt; Denk, Helmut (2007).
351:
Denk, H; Franke, WW; Eckerstorfer, R; Schmid, E; Kerjaschki, D (August 1979).
1211:
1141:
922:
816:
796:
1018:
1013:
879:
645:
553:
518:
425:
408:
369:
264:
241:
156:
152:
50:
477:
434:
1171:
1048:
679:
388:
82:
1121:
932:
864:
855:
847:
837:
689:
684:
650:
635:
256:
233:
164:
113:
34:
509:
492:
662:
655:
630:
172:
160:
78:
1036:
965:
889:
625:
168:
490:
340:– via The University of Utah Eccles Health Sciences Library.
975:
970:
699:
602:
1092:
620:
531:
927:
776:
105:
liver disease and were once thought to be specific for that.
98:
350:
332:. The Internet Pathology Laboratory for Medical Education
199:
for the molecular analysis of the pathogenesis of MDBs.
455:
159:. The bodies themselves are made up of intermediate
1209:
579:
402:
400:
398:
318:
97:Mallory bodies are classically found in the
406:
586:
572:
395:
508:
424:
378:
368:
191:It is named for the American pathologist
92:
29:
45:appearance (centre of image - within a
14:
1210:
567:
211:– another histopathologic finding of
175:, or bound by other proteins such as
219:
24:
283:, as seen in alcohol use disorder.
279:Liver micrograph showing abundant
25:
1234:
123:They are a recognized feature of
27:Pathologic finding in liver cells
407:Jensen, K; Gluud, C (Oct 1994).
288:
272:
249:
226:
263:. Original magnification 200X.
240:. Original magnification 400X.
525:
484:
449:
344:
85:. Mallory bodies are damaged
13:
1:
470:10.1016/S0046-8177(82)80143-3
311:
146:
7:
807:Charcot's cholangitis triad
546:10.1016/j.yexcr.2007.04.024
202:
10:
1239:
534:Experimental Cell Research
151:Mallory bodies are highly
1192:Sister Mary Joseph nodule
1114:
1091:
1029:
996:
953:
910:
903:
846:
768:
609:
186:
129:primary biliary cirrhosis
101:of people suffering from
300:hepatocellular carcinoma
155:and thus appear pink on
137:hepatocellular carcinoma
108:They are most common in
89:within the liver cells.
41:with the characteristic
209:Ballooning degeneration
133:non-alcoholic cirrhosis
599:human digestive system
426:10.1002/hep.1840200440
370:10.1073/pnas.76.8.4112
87:intermediate filaments
54:
885:Obstructed defecation
120:(prevalence of 51%).
93:Associated conditions
47:ballooning hepatocyte
33:
1147:Aure-Rozanova's sign
1106:Hannington-Kiff sign
1101:Howship–Romberg sign
1059:Aortic insufficiency
961:Abdominal distension
326:"Cell Injury No. 39"
712:Chilaiditi syndrome
419:(4 Pt 1): 1061–77.
177:heat shock proteins
118:alcoholic cirrhosis
110:alcoholic hepatitis
1218:Alcohol and health
1079:Grey Turner's sign
1009:Hepatosplenomegaly
938:Abdominal guarding
870:Fecal occult blood
861:Fecal incontinence
832:Mirizzi's syndrome
742:Sherren's triangle
595:Signs and symptoms
193:Frank Burr Mallory
55:
1205:
1204:
1177:Fothergill's sign
1167:Rosenstein's sign
1087:
1086:
1042:Mallet-Guy's sign
981:Shifting dullness
802:Courvoisier's law
540:(10): 2033–2049.
510:10.1002/hep.21744
220:Additional images
71:Mallory's hyaline
67:Mallory–Denk body
16:(Redirected from
1230:
908:
907:
895:Rectal discharge
811:Reynolds' pentad
750:Radiologic signs
737:McBurney's point
611:Gastrointestinal
597:relating to the
588:
581:
574:
565:
564:
558:
557:
529:
523:
522:
512:
488:
482:
481:
453:
447:
446:
428:
404:
393:
392:
382:
372:
348:
342:
341:
339:
337:
322:
292:
276:
253:
230:
125:Wilson's disease
21:
1238:
1237:
1233:
1232:
1231:
1229:
1228:
1227:
1208:
1207:
1206:
1201:
1162:Lockwood's sign
1110:
1083:
1054:Ballance's sign
1025:
992:
986:Fluid wave test
949:
943:Blumberg's sign
899:
875:Rectal tenesmus
842:
782:Councilman body
764:
707:Goodsall's rule
695:Hypersalivation
612:
605:
592:
562:
561:
530:
526:
489:
485:
458:Human Pathology
454:
450:
405:
396:
349:
345:
335:
333:
324:
323:
319:
314:
307:
304:Trichrome stain
293:
284:
277:
268:
254:
245:
231:
222:
213:steatohepatitis
205:
189:
171:that have been
149:
103:alcohol-induced
95:
28:
23:
22:
15:
12:
11:
5:
1236:
1226:
1225:
1223:Histopathology
1220:
1203:
1202:
1200:
1199:
1197:Blumer's shelf
1194:
1189:
1187:Massouh's sign
1184:
1182:Carnett's sign
1179:
1174:
1169:
1164:
1159:
1154:
1149:
1144:
1139:
1137:Hamburger sign
1134:
1132:Rovsing's sign
1129:
1127:Obturator sign
1124:
1118:
1116:
1112:
1111:
1109:
1108:
1103:
1097:
1095:
1089:
1088:
1085:
1084:
1082:
1081:
1076:
1071:
1066:
1064:Castell's sign
1061:
1056:
1051:
1046:
1045:
1044:
1033:
1031:
1027:
1026:
1024:
1023:
1022:
1021:
1016:
1006:
1004:Abdominal mass
1000:
998:
994:
993:
991:
990:
989:
988:
983:
978:
973:
968:
957:
955:
951:
950:
948:
947:
946:
945:
940:
935:
930:
925:
918:Abdominal pain
914:
912:
905:
901:
900:
898:
897:
892:
887:
882:
877:
872:
867:
858:
852:
850:
844:
843:
841:
840:
835:
829:
824:
813:
804:
799:
790:
789:
784:
772:
770:
766:
765:
763:
762:
757:
755:Hampton's line
745:
744:
739:
734:
729:
724:
719:
714:
709:
703:
702:
697:
692:
687:
682:
677:
676:
675:
670:
660:
659:
658:
653:
648:
638:
633:
628:
623:
617:
615:
607:
606:
591:
590:
583:
576:
568:
560:
559:
524:
503:(3): 851–860.
483:
448:
394:
343:
316:
315:
313:
310:
309:
308:
296:Mallory bodies
294:
287:
285:
281:Mallory bodies
278:
271:
269:
255:
248:
246:
232:
225:
221:
218:
217:
216:
204:
201:
188:
185:
181:Sequestosome 1
148:
145:
141:morbid obesity
94:
91:
59:histopathology
26:
18:Mallory bodies
9:
6:
4:
3:
2:
1235:
1224:
1221:
1219:
1216:
1215:
1213:
1198:
1195:
1193:
1190:
1188:
1185:
1183:
1180:
1178:
1175:
1173:
1170:
1168:
1165:
1163:
1160:
1158:
1155:
1153:
1152:Dunphy's sign
1150:
1148:
1145:
1143:
1142:Heel tap sign
1140:
1138:
1135:
1133:
1130:
1128:
1125:
1123:
1120:
1119:
1117:
1113:
1107:
1104:
1102:
1099:
1098:
1096:
1094:
1090:
1080:
1077:
1075:
1074:Cullen's sign
1072:
1070:
1067:
1065:
1062:
1060:
1057:
1055:
1052:
1050:
1047:
1043:
1040:
1039:
1038:
1035:
1034:
1032:
1028:
1020:
1017:
1015:
1012:
1011:
1010:
1007:
1005:
1002:
1001:
999:
995:
987:
984:
982:
979:
977:
974:
972:
969:
967:
964:
963:
962:
959:
958:
956:
952:
944:
941:
939:
936:
934:
931:
929:
926:
924:
923:Acute abdomen
921:
920:
919:
916:
915:
913:
909:
906:
902:
896:
893:
891:
888:
886:
883:
881:
878:
876:
873:
871:
868:
866:
862:
859:
857:
854:
853:
851:
849:
845:
839:
836:
833:
830:
828:
827:LĂ©pine's sign
825:
823:
822:Murphy's sign
819:
818:
817:cholecystitis
814:
812:
808:
805:
803:
800:
798:
795:
792:
791:
788:
785:
783:
780:
778:
774:
773:
771:
767:
761:
758:
756:
753:
751:
747:
746:
743:
740:
738:
735:
733:
732:Markle's sign
730:
728:
727:Arapov's sign
725:
723:
720:
718:
715:
713:
710:
708:
705:
704:
701:
698:
696:
693:
691:
688:
686:
683:
681:
678:
674:
671:
669:
668:oropharyngeal
666:
665:
664:
661:
657:
654:
652:
649:
647:
644:
643:
642:
639:
637:
634:
632:
629:
627:
624:
622:
619:
618:
616:
614:
608:
604:
600:
596:
589:
584:
582:
577:
575:
570:
569:
566:
555:
551:
547:
543:
539:
535:
528:
520:
516:
511:
506:
502:
498:
494:
487:
479:
475:
471:
467:
463:
459:
452:
444:
440:
436:
432:
427:
422:
418:
414:
410:
403:
401:
399:
390:
386:
381:
376:
371:
366:
363:(8): 4112–6.
362:
358:
354:
347:
331:
327:
321:
317:
305:
301:
297:
291:
286:
282:
275:
270:
266:
265:H&E stain
262:
258:
252:
247:
243:
242:H&E stain
239:
235:
229:
224:
223:
214:
210:
207:
206:
200:
198:
194:
184:
182:
178:
174:
173:ubiquitinated
170:
166:
162:
161:cytokeratin 8
158:
157:H&E stain
154:
144:
142:
138:
134:
130:
126:
121:
119:
115:
111:
106:
104:
100:
90:
88:
84:
80:
77:found in the
76:
72:
68:
64:
60:
52:
51:H&E stain
48:
44:
40:
36:
32:
19:
1157:Alder's sign
1019:Splenomegaly
1014:Hepatomegaly
880:Constipation
815:
793:
787:Mallory body
786:
775:
760:Klemm's sign
748:
722:Aaron's sign
717:Dance's sign
646:Trichophagia
537:
533:
527:
500:
496:
486:
461:
457:
451:
416:
412:
360:
356:
346:
334:. Retrieved
329:
320:
295:
280:
261:Mallory body
260:
238:Mallory body
237:
190:
153:eosinophilic
150:
122:
116:of 65%) and
107:
96:
70:
66:
63:Mallory body
62:
56:
43:twisted-rope
42:
39:Mallory body
38:
1172:Cupola sign
1069:Kehr's sign
1049:Puddle sign
680:Odynophagia
464:(1): 81–5.
197:Helmut Denk
83:liver cells
1212:Categories
1122:Psoas sign
954:Distension
933:Baby colic
865:encopresis
856:Flatulence
848:Defecation
838:Nardi test
797:Boas' sign
690:Xerostomia
685:Bad breath
673:esophageal
651:Pagophagia
636:Aerophagia
497:Hepatology
413:Hepatology
336:25 October
312:References
259:showing a
257:Micrograph
236:showing a
234:Micrograph
147:Appearance
139:(23%) and
114:prevalence
69:(MDB), or
37:showing a
35:Micrograph
769:Accessory
663:Dysphagia
656:Geophagia
631:Heartburn
179:, or p62/
167:filament
79:cytoplasm
75:inclusion
1037:Jaundice
966:Bloating
890:Diarrhea
794:biliary:
626:Vomiting
554:17531973
519:17685470
443:44400893
203:See also
169:proteins
976:Tympany
971:Ascites
904:Abdomen
700:Burping
603:abdomen
478:6176520
435:7927209
330:WebPath
135:(24%),
131:(24%),
127:(25%),
1093:Hernia
997:Masses
621:Nausea
552:
517:
476:
441:
433:
389:386356
387:
380:383988
377:
187:Eponym
99:livers
73:is an
1115:Other
1030:Other
928:Colic
777:liver
613:tract
439:S2CID
911:Pain
863:and
641:Pica
550:PMID
515:PMID
474:PMID
431:PMID
385:PMID
338:2023
61:, a
601:or
542:doi
538:313
505:doi
466:doi
421:doi
375:PMC
365:doi
298:in
81:of
57:In
49:).
1214::
548:.
536:.
513:.
501:46
499:.
495:.
472:.
462:13
460:.
437:.
429:.
417:20
415:.
411:.
397:^
383:.
373:.
361:76
359:.
355:.
328:.
302:.
183:.
165:18
65:,
834:)
820:(
809:/
779::
752::
587:e
580:t
573:v
556:.
544::
521:.
507::
480:.
468::
445:.
423::
391:.
367::
306:.
267:.
244:.
215:.
163:/
112:(
53:.
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
