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Oropharyngeal cancer

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32: 687: 508: 1701: 705:, which normally increases in the presence of HPV. Some people can have elevated levels of p16 but test negative for HPV and vice versa. This is known as discordant cancer. The five-year survival for people who test positive for HPV and p16 is 81%, for discordant cancer it is 53 – 55%, and 40% for those who test negative for p16 and HPV. The 709:
for people with oropharyngeal cancer depends on the age and health of the person and the stage of the disease. It is important for people with oropharyngeal cancer to have follow-up exams for the rest of their lives, as cancer can occur in nearby areas. In addition, it is important to eliminate risk
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Traditionally, oropharyngeal cancer has been managed through combination of surgery and radiotherapy. Other treatments have been developed including a combination of surgery, radiotherapy, chemotherapy and immunotherapy, but with limited improvement in survival rates. Studies comparing different
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of observed abnormal tissue in the throat. Oropharyngeal cancer is staged according to the appearance of the abnormal cells on the biopsy coupled with the dimensions and the extent of the abnormal cells found. Treatment is with surgery, chemotherapy, or radiation therapy; or some combination of
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Mehanna, Hisham; Taberna, Miren; von Buchwald, Christian; Tous, Sara; Brooks, Jill; Mena, Marisa; Morey, Francisca; Grønhøj, Christian; Rasmussen, Jacob Høygaard; Garset-Zamani, Martin; Bruni, Laia; Batis, Nikolaos; Brakenhoff, Ruud H; Leemans, C René; Baatenburg de Jong, Robert J (March 2023).
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Muñoz N, Bosch FX, de SanjosĂ© S, Herrero R, CastellsaguĂ© X, Shah KV, et al. (International Agency for Research on Cancer Multicenter Cervical Cancer Study Group) (February 2003). "Epidemiologic classification of human papillomavirus types associated with cervical cancer".
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Cancer is any size and has spread to one lymph node that is larger than 30 mm, but not larger than 60 mm on the same side of the neck as the cancer or to more than one lymph node, none larger than 60 mm, on one of both sides of the
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Takes RP, Wierzbicka M, D'Souza G, Jackowska J, Silver CE, Rodrigo JP, et al. (December 2015). "HPV vaccination to prevent oropharyngeal carcinoma: What can be learned from anogenital vaccination programs?".
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in the neck or has spread to bones in the jaw or skull, to muscle in the side of the jaw, or to the upper part of the throat behind the nose, and may have spread to nearby lymph nodes.
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Sore or blister in back of mouth, difficulty with speech, swallowing or breathing, swelling in neck, loss of appetite, loss of weight, and weakness
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combinations of treatment on patient outcomes have shown insufficient evidence that any treatment combination is superior to others.
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Cancer has formed and is larger than 20 mm, but not larger than 40 mm. Also, it has not yet spread outside the oropharynx.
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Bulsara, Vishal M.; Worthington, Helen V.; Glenny, Anne-Marie; Clarkson, Janet E.; Conway, David I.; Macluskey, Michaelina (2018).
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Cancer has spread to a lymph node that is larger than 60 mm and may have spread to tissues around the oropharynx.
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released a statement indicating that he had been diagnosed with oropharyngeal cancer in late June of the same year.
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Cancer has spread to tissues near the oropharynx, including the larynx (voice box), roof of the mouth,
651:. A research conducted in 2017 demonstrated that HPV vaccination induces HPV antibodies levels at the 647:
show more than 90% efficacy in preventing vaccine-type HPV infections and their correlated anogenital
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on the same side of the neck as the cancer. The lymph node with cancer is 30 mm or smaller.
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Helgadottir H, Höiom V, Jönsson G, Tuominen R, Ingvar C, Borg A, et al. (August 2014).
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died of oropharyngeal cancer, on the eve of the 20th anniversary of the first broadcast of
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factors such as smoking and drinking alcohol, which increase the risk for second cancers.
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Cancer has formed and is 20 mm or smaller and has not spread outside the oropharynx.
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tend to have higher survival rates. However, HPV is tested for by the presence of the
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3D medical illustration showing the cancer formation in the tissues of the oropharynx
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The risk factors that can increase the risk of developing oropharyngeal cancer are:
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is of the prime importance in the control and prevention of oropharyngeal cancers.
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Oropharyngeal cancer (from right tonsil, HPV-negative), T4a N2c, 48-year-old man.
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Cancer is larger than 40 mm and has not spread outside the oropharynx.
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Regarding the primary prevention of HPV-positive oropharyngeal cancer,
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Isayeva T, Li Y, Maswahu D, Brandwein-Gensler M (July 2012).
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Certain genetic changes including: P53 mutation and CDKN2A (
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The signs and symptoms of oropharyngeal cancer may include:
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Ljubojevic S, Skerlev M (2014). "HPV-associated diseases".
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died from oropharyngeal cancer three years after diagnosis.
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Types of oropharyngeal cancer and associated survival rates
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and travels through the blood to other places in the body.
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Idrees M, Kujan O, Shearston K, Farah CS (January 2020).
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reported that he was diagnosed with oropharyngeal cancer.
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Sideropenic dysphagia (Paterson-Kelly-Brown syndrome).
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may be any size and may have spread to lymph nodes.
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Index

Image of human papilloma virus associated oropharyngeal cancer, under a microscope. The tissue has been stained to show the presence of the virus by in situ hybridisation
Specialty
Oncology
head and neck surgery
Symptoms
Human papillomavirus
tobacco use
smoking
chewing
alcohol use disorder
long-term effects
Diagnostic method
Endoscopy
biopsy
staining
p16
CT scan
HPV vaccine
Surgery
radiation
chemotherapy
oral cavity
oropharynx
base of the tongue
tonsils
palate
pharynx
HPV-positive oropharyngeal cancer
human papillomavirus infection
use of alcohol

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