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Parkinsonism

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Parkinsonian syndromes are a group of movement disorders characterized by classical motor symptoms such as tremors, bradykinesia, and rigidity. They are most frequently due to primary neurodegenerative disease, resulting in the loss of dopaminergic nerve terminals along the nigrostriatal pathway,
4314: 4291: 4276: 3301: 792:. The incidence of drug-induced parkinsonism increases with age. Drug-induced parkinsonism tends to remain at its presenting level and does not worsen like Parkinson's disease. 3687: 3682: 170:. Both hypokinetic (bradykinesia and akinesia) as well as hyperkinetic (cogwheel rigidity and tremors at rest) features are displayed by Parkinsonism. These are the four 3699: 3677: 2850: 2276:
Apartis E, Tison F, Arné P, Jedynak CP, Vidailhet M (November 2001). "Fast orthostatic tremor in Parkinson's disease mimicking primary orthostatic tremor".
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gene, a manganese efflux transporter necessary for decreasing intracellular Mn, has been linked with the development of this parkinsonism-like disease. The
2194:"Parkinsonism following bilateral lesions of the globus pallidus: performance on a variety of motor tasks shows similarities with Parkinson's disease" 383: 3046: 2780: 428: 535:(Mn) exposure has been shown to produce a parkinsonism-like illness characterized by movement abnormalities. This condition is not responsive to 4391: 3780: 3041: 2632: 432: 4009: 2074:"Pearls & Oy-sters: Arteriovenous Malformation With Sinus Thrombosis and Thalamic Hemorrhage: Unusual Cause of Parkinsonism and Dementia" 2843: 845: 2794: 2419:
Saito M, Maruyama M, Ikeuchi K, Kondo H, Ishikawa A, Yuasa T, et al. (September 2000). "Autosomal recessive juvenile parkinsonism".
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Uitti RJ, Snow BJ, Shinotoh H, Vingerhoets FJ, Hayward M, Hashimoto S, et al. (May 1994). "Parkinsonism induced by solvent abuse".
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Christine CW, Aminoff MJ (September 2004). "Clinical differentiation of parkinsonian syndromes: prognostic and therapeutic relevance".
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Weiss J. Chapter 151. Toluene and Xylene. In: Olson KR, ed. Poisoning & Drug Overdose. 6th ed. New York: McGraw-Hill; 2012.
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Maltête D, Guyant-Maréchal L, Mihout B, Hannequin D (March 2006). "Movement disorders and Creutzfeldt-Jakob disease: a review".
186:(PDD), and many other conditions. This set of symptoms occurs in a wide range of conditions and may have many causes, including 3639: 3312: 4224: 3664: 3296: 1159: 964: 878: 3502: 3490: 2952: 536: 4006: 1347:
Tse W, Cersosimo MG, Gracies JM, Morgello S, Olanow CW, Koller W (August 2004). "Movement disorders and AIDS: a review".
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About 7% of people with parkinsonism developed symptoms as a result of side effects of medication, mainly neuroleptic
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Jubault T, Brambati SM, Degroot C, Kullmann B, Strafella AP, Lafontaine AL, et al. (December 2009).
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Armenteros PR, Kapetanovic S, Lopez SG, Vazquez-Lorenzo E, Mendez LA, Muga JJ, et al. (2022-03-29).
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Pezzoli G, Cereda E (May 2013). "Exposure to pesticides or solvents and risk of Parkinson disease".
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Fabrizi, Monaco, Dalla Libera (2004). "Parkinsonian syndrome following MDMA (Ecstasy) addiction".
1907:"Intracranial dural arteriovenous fistula (DAVF) presenting progressive dementia and parkinsonism" 565:
may be a cause of parkinsonism, although evidence is inconclusive and further research is needed.
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Peres TV, Schettinger MR, Chen P, Carvalho F, Avila DS, Bowman AB, et al. (November 2016).
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McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, et al. (July 2017).
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Ogawa T, Fujii S, Kuya K, Kitao SI, Shinohara Y, Ishibashi M, et al. (September 2018).
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Jankovic J, Lang AE (2004). "Diagnosis and Assessment". In Bradley, Walter George (ed.).
899:"Role of neuroimaging on differentiation of Parkinson's disease and its related diseases" 785: 643: 461: 413: 274: 241:
problems can lead to falls and serious physical injuries. Other common symptoms include:
2515:"Clinical Aspects of the Differential Diagnosis of Parkinson's Disease and Parkinsonism" 2490: 2463: 2150: 4031: 3830: 3632: 3617: 3605: 3355: 3306: 3143: 3006: 2894: 2738: 2713: 2689: 2664: 2614: 2539: 2514: 2444: 2396: 2370:"A case of rapid-onset dystonia-parkinsonism accompanied by pyramidal tract impairment" 2369: 2345: 2320: 2301: 2218: 2193: 2169: 2134: 2111: 2054: 1994: 1961: 1942: 1882: 1849: 1830: 1769: 1742: 1709:"Mechanisms of MPTP toxicity and their implications for therapy of Parkinson's disease" 1684: 1659: 1613: 1559: 1532: 1508: 1481: 1454: 1429: 1407: 1289: 1264: 1240: 1215: 1058: 1023: 923: 898: 728:
Secondary parkinsonism, including vascular parkinsonism and drug-induced parkinsonism.
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Kuoppamäki M, Rothwell JC, Brown RG, Quinn N, Bhatia KP, Jahanshahi M (April 2005).
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Matsuda S, Waragai M, Shinotoh H, Takahashi N, Takagi K, Hattori T (1999-05-01).
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MartĂ­-MassĂł JF, Poza JJ (1 May 1998). Stoessl AJ, Klein C, Standaert DG (eds.).
840:(NDAA) added parkinsonism to the list of presumptive conditions associated with 51: 4345: 4235: 4204: 3978: 3497: 3446: 3274: 2983: 2860: 1675: 809: 799: 784:, usually prescribed for motion sickness; this is because besides antagonizing 777: 773: 761: 749: 700: 626: 470: 252: 2530: 2386: 1960:
Kim HR, Lee JY, Kim YK, Park H, Kim HJ, Son YJ, et al. (September 2015).
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Aminoff MJ, Greenberg DA, Simon RP (2005). "Chapter 7: Movement disorders".
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Dural arteriovenous malformation / dAVM (reversible through dAVM treatment)
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Kwakye GF, Paoliello MM, Mukhopadhyay S, Bowman AB, Aschner M (July 2015).
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Syndrome characterized by tremor, slowed movements, rigidity, and imbalance
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Liu Y, Lu Y, Zhang X, Xie S, Wang T, Wu T, et al. (November 2016).
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Del Toro-Pérez C, Guevara-Sánchez E, Martínez-Sánchez P (March 2023).
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Neurology in Clinical Practice: Principles of diagnosis and management
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Halliday GM (2009-12-15). "Thalamic changes in Parkinson's disease".
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Spinal muscular atrophy with lower extremity predominance (SMALED)
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Goldstein S, Friedman JH, Innis R, Seibyl J, Marek K (March 2001).
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International Journal of Environmental Research and Public Health
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International Journal of Environmental Research and Public Health
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GeneReviews/NCBI/NIH/UW entry on X-Linked Dystonia-Parkinsonism
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Other toxins that have been associated with parkinsonism are:
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Barrett KE, Barman SM, Brooks HL, Yuan J (21 January 2019).
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Shuaib UA, Rajput AH, Robinson CA, Rajput A (March 2016).
2662: 2797:. U. S. Department of Veteran Affairs. September 10, 2021 2464:"Treatment of Vascular Parkinsonism: A Systematic Review" 2418: 493: 397: 1848:
Lai J, Heran MK, Stoessl AJ, Gooderham PA (2017-03-27).
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http://www.accessmedicine.com/content.aspx?aID=55982958
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exposure, enabling affected service members to receive
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typical to PD are not seen in Mn-induced parkinsonism.
868: 539:, suggesting an alternative pathway than the typical 4258: 2567:"Cinnarizine-induced parkinsonism: ten years later" 1706: 1256: 896: 508:Evidence exists to show a link between exposure to 2198:Journal of Neurology, Neurosurgery, and Psychiatry 516:and PD; a two-fold increase in risk was seen with 2638:. Parkinson's Disease and Society. Archived from 1743:"Environmental Exposures and Parkinson's Disease" 938:similar to idiopathic PD, MSA, PSP, CBD, and DLB. 4383: 1427: 986: 429:Pantothenate kinase-associated neurodegeneration 2819:GeneReviews/NIH/NCBI/UW entry on Perry syndrome 2564: 1740: 1423: 1421: 674:(boxer's dementia or pugilistic encephalopathy) 3788: 2787: 2633:"Information Sheet: Drug-induced Parkinsonism" 2560: 2558: 1707:Watanabe Y, Himeda T, Araki T (January 2005). 1660:"Occupational neurological disorders in Korea" 1150:. Vol. 1. Taylor & Francis. pp.  1141: 1139: 1137: 1135: 1133: 1131: 1129: 1127: 1125: 1123: 1121: 1119: 1117: 1115: 1113: 1111: 1109: 1107: 1105: 1103: 1101: 1099: 1097: 864: 862: 860: 433:neurodegeneration with brain iron accumulation 3774: 2844: 2795:"VA adds three new Agent Orange presumptions" 2367: 1959: 1700: 1475: 1473: 1381: 1174: 1095: 1093: 1091: 1089: 1087: 1085: 1083: 1081: 1079: 1077: 1021: 537:typical therapies used in the treatment of PD 198:, and neurological conditions other than PD. 2779:: CS1 maint: multiple names: authors list ( 2512: 2318: 1581: 1575: 1418: 1145: 731: 3563: 2711: 2555: 1630: 1375: 857: 324:Plastic, dead feeling resistance known as " 3781: 3767: 2851: 2837: 1470: 1074: 69: 50: 2737: 2688: 2538: 2489: 2479: 2395: 2385: 2344: 2217: 2168: 2158: 2089: 1993: 1881: 1768: 1758: 1734: 1683: 1599: 1558: 1548: 1524: 1507: 1497: 1453: 1288: 1239: 1207: 1057: 1039: 922: 723: 719:Autosomal recessive juvenile parkinsonism 2240: 1741:Nandipati S, Litvan I (September 2016). 1428:Guilarte TR, Gonzales KK (August 2015). 337:Parkinsonism occurs in many conditions. 1657: 1651: 948: 946: 681:(especially dopaminergic nuclei of the 384:Gerstmann–Sträussler–Scheinker syndrome 14: 4384: 3640:Distal hereditary motor neuronopathies 3313:Template:Demyelinating diseases of CNS 2513:Shin HW, Hong SW, Youn YC (May 2022). 1213: 831: 4392:Extrapyramidal and movement disorders 3762: 2832: 956:Ganong's Review of Medical Physiology 352:that can cause parkinsonism include: 201: 3491:Idiopathic intracranial hypertension 2880: 2712:Louis ED, Ottman R (November 2013). 2243:Parkinsonism & Related Disorders 1911:Journal of the Neurological Sciences 1854:Movement Disorders Clinical Practice 1582:McKnight S, Hack N (November 2020). 1349:Parkinsonism & Related Disorders 1314:Parkinsonism & Related Disorders 1181:Parkinsonism & Related Disorders 1175:Algarni M, Fasano A (January 2018). 943: 24: 3722:Infantile progressive bulbar palsy 2319:Panzer J, Dalmau J (August 2011). 838:National Defense Authorization Act 547:. Manganese may accumulate in the 25: 4413: 3425:Template:Cerebrovascular diseases 3228:Frontotemporal lobar degeneration 2812: 1664:Journal of Korean Medical Science 1658:Kim EA, Kang SK (December 2010). 1537:BMC Pharmacology & Toxicology 716:Rapid onset dystonia parkinsonism 100:Other neurodegenerative disorders 3445:For more detailed coverage, see 3423:For more detailed coverage, see 3394:For more detailed coverage, see 3360:For more detailed coverage, see 3311:For more detailed coverage, see 1361:10.1016/j.parkreldis.2004.03.001 1326:10.1016/j.parkreldis.2005.10.004 1193:10.1016/j.parkreldis.2017.07.006 989:The American Journal of Medicine 795:Implicated medications include: 672:Chronic traumatic encephalopathy 2754: 2705: 2656: 2625: 2506: 2455: 2412: 2361: 2312: 2269: 2234: 2185: 2122: 2065: 2010: 1953: 1898: 1841: 1798: 1785: 1624: 1340: 1305: 836:In the United States, the 2021 366:The relationship (if any) with 340: 4197:Adenosine receptor antagonists 1168: 1022:Kwan LC, Whitehill TL (2011). 1015: 980: 467:X-linked dystonia parkinsonism 457:Progressive supranuclear palsy 419:Neuronal ceroid lipofuscinosis 108:progressive supranuclear palsy 13: 1: 3738:Amyotrophic lateral sclerosis 3623:Hereditary spastic paraplegia 3481:Normal pressure hydrocephalus 2718:European Journal of Neurology 2433:10.1016/s0387-7604(00)00137-6 2255:10.1016/S1353-8020(09)70804-1 1966:Journal of Movement Disorders 1923:10.1016/s0022-510x(99)00075-1 851: 477: 332: 318:(jerky feeling in arm or leg) 3707:Progressive muscular atrophy 2337:10.1097/WCO.0b013e328347b307 2325:Current Opinion in Neurology 2160:10.1371/journal.pone.0008247 2091:10.1212/WNL.0000000000200016 1584:"Toxin-Induced Parkinsonism" 1396:10.1212/WNL.0b013e318294b3c8 1281:10.1212/WNL.0000000000004058 1232:10.1212/CON.0000000000000300 1001:10.1016/j.amjmed.2004.03.032 959:(26 ed.). McGraw Hill. 817:(addiction and frequent use) 452:Parkinson's disease dementia 442:hereditary juvenile dystonia 424:Olivopontocerebellar atrophy 184:Parkinson's disease dementia 95:Parkinson's disease dementia 7: 3217:Primary progressive aphasia 1631:Carod-Artal FJ (2003). "". 848:disability benefits.  656:Dural arteriovenous fistula 633: 206:Parkinsonism is a clinical 132:Dural arteriovenous fistula 10: 4418: 3539:Hashimoto's encephalopathy 3245:Posterior cortical atrophy 3066:Striatonigral degeneration 2917:Cavernous sinus thrombosis 1795:. Accessed April 21, 2013. 1676:10.3346/jkms.2010.25.S.S26 1216:"Frontotemporal Dementias" 788:this drug antagonizes the 290:Lack of facial expressions 210:characterized by the four 138:arteriovenous malformation 31: 4355: 4262: 4219: 4171: 4063: 4005: 3974: 3943: 3864: 3810: 3801: 3645:Spinal muscular atrophies 3613:Primary lateral sclerosis 3595: 3572: 3556: 3511: 3471:Intracranial hypertension 3461: 3433: 3404: 3370: 3332: 3321: 3287: 3265: 3251:Creutzfeldt–Jakob disease 3190: 3000: 2991: 2977: 2937: 2871: 2531:10.3988/jcn.2022.18.3.259 2387:10.1186/s12883-016-0743-8 1601:10.1016/j.ncl.2020.08.003 1550:10.1186/s40360-016-0099-0 732:Drug-induced parkinsonism 503: 484:Creutzfeldt–Jakob disease 362:Dementia with Lewy bodies 357:Corticobasal degeneration 180:dementia with Lewy bodies 112:corticobasal degeneration 90:Dementia with Lewy bodies 78: 58: 49: 44: 3712:Progressive bulbar palsy 3503:Intracranial hypotension 3486:Choroid plexus papilloma 2900:Herpesviral encephalitis 2481:10.3390/brainsci13030489 2210:10.1136/jnnp.2003.020800 1214:Finger EC (April 2016). 915:10.33160/yam.2018.09.001 665: 350:Parkinson-plus syndromes 268:leading to soft speech, 3224:Frontotemporal dementia 2910:Encephalitis lethargica 2421:Brain & Development 1716:Medical Science Monitor 1635:(Review) (in Spanish). 1499:10.3390/ijerph120707519 711:Paraneoplastic syndrome 489:Encephalitis lethargica 404:Multiple system atrophy 374:Frontotemporal dementia 104:multiple system atrophy 3529:Hepatic encephalopathy 1760:10.3390/ijerph13090881 1434:Toxicological Sciences 1226:(2 Dementia): 464–89. 1187:(Suppl 1): S101–S104. 724:Differential diagnosis 306:Very small handwriting 4040:+carbidopa/entacapone 3835:+carbidopa/entacapone 3587:Ataxia–telangiectasia 3544:Static encephalopathy 3267:Mitochondrial disease 3105:Spasmodic torticollis 3015:Basal ganglia disease 2595:10.1002/mds.870130313 1819:10.1002/ana.410350516 1633:Revista de NeurologĂ­a 1446:10.1093/toxsci/kfv099 790:dopamine D2 receptors 3790:Antiparkinson agents 3534:Toxic encephalopathy 3240:Lewy bodies dementia 640:Binswanger's disease 394:Lytico-bodig disease 389:Huntington's disease 311:Rigid, stiff muscles 232:postural instability 226:(slowed movements), 168:postural instability 162:(slowed movements), 4402:Parkinson's disease 3890:Dihydroergocryptine 3582:Friedreich's ataxia 2965:Meningoencephalitis 2905:Limbic encephalitis 2427:(Suppl 1): S115-7. 2151:2009PLoSO...4.8247J 1807:Annals of Neurology 1041:10.4061/2011/389767 1028:Parkinson's Disease 832:Society and culture 786:histamine receptors 644:leukoencephalopathy 447:Parkinson's disease 414:Neuroacanthocytosis 408:Shy–Drager syndrome 275:Difficulty sleeping 216:Parkinson's disease 190:conditions, drugs, 176:Parkinson's disease 85:Parkinson's disease 34:Parkinson's disease 4356:External resources 4246:Never to phase III 3618:Pseudobulbar palsy 3356:Status epilepticus 3307:Multiple sclerosis 3144:Myoclonic epilepsy 3007:movement disorders 2953:Acute disseminated 2895:Viral encephalitis 2763:Movement Disorders 2669:Movement Disorders 2571:Movement Disorders 2278:Movement Disorders 2023:Movement Disorders 1978:10.14802/jmd.15021 1866:10.1002/mdc3.12480 871:Clinical Neurology 706:Orthostatic tremor 326:lead-pipe rigidity 202:Signs and symptoms 196:metabolic diseases 4379: 4378: 4256: 4255: 4059: 4058: 3756: 3755: 3752: 3751: 3748: 3747: 3552: 3551: 3457: 3456: 3396:Template:Headache 3362:Template:Epilepsy 3283: 3282: 3257:Vascular dementia 3100:Status dystonicus 2973: 2972: 2948:Encephalomyelitis 2730:10.1111/ene.12256 2681:10.1002/mds.26467 1670:(Suppl): S26-35. 1386:(Meta-analysis). 1161:978-99976-25-88-5 966:978-1-260-12241-1 880:978-0-07-142360-1 650:Vascular dementia 346:Neurodegenerative 321:Upgaze impairment 188:neurodegenerative 154:characterized by 145: 144: 127:Metabolic disease 39:Medical condition 16:(Redirected from 4409: 4260: 4259: 4088:Chlorphenoxamine 4065:Anticholinergics 3808: 3807: 3783: 3776: 3769: 3760: 3759: 3570: 3569: 3561: 3560: 3519:Brain herniation 3330: 3329: 3170:Intention tremor 3165:Essential tremor 3030:Postencephalitic 2998: 2997: 2989: 2988: 2878: 2877: 2859:Diseases of the 2853: 2846: 2839: 2830: 2829: 2807: 2806: 2804: 2802: 2791: 2785: 2784: 2778: 2770: 2758: 2752: 2751: 2741: 2709: 2703: 2702: 2692: 2660: 2654: 2653: 2651: 2650: 2644: 2637: 2629: 2623: 2622: 2583:British Columbia 2562: 2553: 2552: 2542: 2510: 2504: 2503: 2493: 2483: 2459: 2453: 2452: 2416: 2410: 2409: 2399: 2389: 2365: 2359: 2358: 2348: 2316: 2310: 2309: 2290:10.1002/mds.1218 2273: 2267: 2266: 2238: 2232: 2231: 2221: 2189: 2183: 2182: 2172: 2162: 2126: 2120: 2119: 2093: 2069: 2063: 2062: 2035:10.1002/mds.1047 2014: 2008: 2007: 1997: 1957: 1951: 1950: 1902: 1896: 1895: 1885: 1845: 1839: 1838: 1802: 1796: 1789: 1783: 1782: 1772: 1762: 1738: 1732: 1731: 1713: 1704: 1698: 1697: 1687: 1655: 1649: 1648: 1628: 1622: 1621: 1603: 1579: 1573: 1572: 1562: 1552: 1528: 1522: 1521: 1511: 1501: 1477: 1468: 1467: 1457: 1425: 1416: 1415: 1379: 1373: 1372: 1344: 1338: 1337: 1309: 1303: 1302: 1292: 1260: 1254: 1253: 1243: 1211: 1205: 1204: 1172: 1166: 1165: 1143: 1072: 1071: 1061: 1043: 1019: 1013: 1012: 984: 978: 977: 975: 973: 950: 941: 940: 926: 894: 885: 884: 866: 846:Veterans Affairs 683:substantia nigra 583:Carbon disulfide 545:substantia nigra 543:loss within the 462:Wilson's disease 431:, also known as 400:complex of Guam) 368:essential tremor 295:Balance problems 266:sound perception 257:Slow movements ( 74: 73: 54: 42: 41: 21: 4417: 4416: 4412: 4411: 4410: 4408: 4407: 4406: 4382: 4381: 4380: 4375: 4374: 4351: 4350: 4271: 4257: 4252: 4251: 4236:Clinical trials 4215: 4167: 4158:Trihexyphenidyl 4133:Phenglutarimide 4113:Etybenzatropine 4103:Diphenhydramine 4055: 4001: 3970: 3939: 3860: 3797: 3787: 3757: 3744: 3670:Congenital DSMA 3591: 3548: 3507: 3453: 3441:Sleep disorders 3429: 3406:Cerebrovascular 3400: 3366: 3323: 3317: 3279: 3261: 3186: 3132:Choreoathetosis 3005: 2982: 2969: 2933: 2867: 2857: 2815: 2810: 2800: 2798: 2793: 2792: 2788: 2772: 2771: 2759: 2755: 2710: 2706: 2661: 2657: 2648: 2646: 2642: 2635: 2631: 2630: 2626: 2563: 2556: 2511: 2507: 2460: 2456: 2417: 2413: 2366: 2362: 2317: 2313: 2274: 2270: 2239: 2235: 2190: 2186: 2127: 2123: 2084:(13): 550–553. 2070: 2066: 2015: 2011: 1958: 1954: 1903: 1899: 1846: 1842: 1803: 1799: 1790: 1786: 1739: 1735: 1711: 1705: 1701: 1656: 1652: 1629: 1625: 1580: 1576: 1529: 1525: 1478: 1471: 1426: 1419: 1390:(22): 2035–41. 1380: 1376: 1345: 1341: 1310: 1306: 1261: 1257: 1212: 1208: 1173: 1169: 1162: 1144: 1075: 1020: 1016: 985: 981: 971: 969: 967: 951: 944: 903:Yonago Acta Med 895: 888: 881: 867: 858: 854: 834: 774:antidepressants 772:), and rarely, 740:especially the 734: 726: 691:globus pallidus 668: 652:(multi-infarct) 636: 578:Carbon monoxide 506: 480: 438:Parkin mutation 348:conditions and 343: 335: 204: 68: 40: 37: 28: 23: 22: 15: 12: 11: 5: 4415: 4405: 4404: 4399: 4394: 4377: 4376: 4373: 4372: 4360: 4359: 4357: 4353: 4352: 4349: 4348: 4337: 4326: 4311: 4288: 4272: 4267: 4266: 4264: 4263:Classification 4254: 4253: 4250: 4249: 4248: 4247: 4244: 4233: 4227: 4221: 4220: 4217: 4216: 4214: 4213: 4208: 4205:istradefylline 4194: 4175: 4173: 4169: 4168: 4166: 4165: 4160: 4155: 4150: 4145: 4140: 4135: 4130: 4125: 4120: 4115: 4110: 4105: 4100: 4095: 4090: 4085: 4080: 4075: 4069: 4067: 4061: 4060: 4057: 4056: 4054: 4053: 4043: 4025: 4014: 4012: 4003: 4002: 4000: 3999: 3994: 3989: 3983: 3981: 3972: 3971: 3969: 3968: 3963: 3958: 3952: 3950: 3941: 3940: 3938: 3937: 3932: 3927: 3922: 3917: 3912: 3903: 3902: 3897: 3892: 3887: 3882: 3873: 3871: 3862: 3861: 3859: 3858: 3848: 3838: 3819: 3817: 3805: 3799: 3798: 3786: 3785: 3778: 3771: 3763: 3754: 3753: 3750: 3749: 3746: 3745: 3743: 3742: 3741: 3740: 3729: 3728: 3727: 3726: 3725: 3724: 3719: 3709: 3704: 3703: 3702: 3697: 3692: 3691: 3690: 3685: 3680: 3672: 3667: 3662: 3657: 3652: 3642: 3628: 3627: 3626: 3625: 3620: 3615: 3601: 3599: 3593: 3592: 3590: 3589: 3584: 3578: 3576: 3567: 3558: 3554: 3553: 3550: 3549: 3547: 3546: 3541: 3536: 3531: 3526: 3521: 3515: 3513: 3509: 3508: 3506: 3505: 3500: 3498:Cerebral edema 3495: 3494: 3493: 3488: 3483: 3478: 3467: 3465: 3459: 3458: 3455: 3454: 3452: 3451: 3450: 3449: 3447:Template:Sleep 3437: 3435: 3431: 3430: 3428: 3427: 3421: 3416: 3410: 3408: 3402: 3401: 3399: 3398: 3392: 3387: 3382: 3376: 3374: 3368: 3367: 3365: 3364: 3358: 3353: 3348: 3342: 3340: 3327: 3319: 3318: 3316: 3315: 3309: 3304: 3299: 3293: 3291: 3285: 3284: 3281: 3280: 3278: 3277: 3275:Leigh syndrome 3271: 3269: 3263: 3262: 3260: 3259: 3248: 3247: 3242: 3237: 3236: 3235: 3221: 3220: 3219: 3214: 3213: 3212: 3196: 3194: 3188: 3187: 3185: 3184: 3179: 3174: 3173: 3172: 3167: 3156: 3155: 3154: 3153: 3148: 3147: 3146: 3136: 3135: 3134: 3124: 3119: 3118: 3117: 3112: 3107: 3102: 3086: 3085: 3084: 3083: 3078: 3073: 3068: 3063: 3062: 3061: 3051: 3050: 3049: 3039: 3038: 3037: 3032: 3027: 3011: 3009: 3002:Extrapyramidal 2995: 2986: 2984:encephalopathy 2975: 2974: 2971: 2970: 2968: 2967: 2962: 2957: 2956: 2955: 2944: 2942: 2935: 2934: 2932: 2931: 2930: 2929: 2919: 2914: 2913: 2912: 2907: 2902: 2897: 2886: 2884: 2875: 2869: 2868: 2861:nervous system 2856: 2855: 2848: 2841: 2833: 2827: 2826: 2821: 2814: 2813:External links 2811: 2809: 2808: 2786: 2753: 2724:(11): 1440–4. 2704: 2655: 2624: 2554: 2525:(3): 259–270. 2505: 2454: 2411: 2360: 2311: 2268: 2233: 2184: 2121: 2064: 2029:(2): 350–353. 2009: 1972:(3): 141–143. 1952: 1897: 1860:(4): 607–611. 1840: 1797: 1784: 1733: 1722:(1): RA17-23. 1699: 1650: 1623: 1594:(4): 853–865. 1574: 1523: 1492:(7): 7519–40. 1469: 1417: 1374: 1339: 1304: 1255: 1206: 1167: 1160: 1073: 1014: 979: 965: 942: 886: 879: 855: 853: 850: 833: 830: 829: 828: 823: 818: 812: 810:Metoclopramide 807: 802: 800:Antipsychotics 778:antihistaminic 766:butyrophenones 762:zuclopenthixol 750:chlorpromazine 742:phenothiazines 738:antipsychotics 733: 730: 725: 722: 721: 720: 717: 714: 708: 703: 701:Hypothyroidism 698: 677:Damage to the 675: 667: 664: 663: 662: 659: 653: 647: 635: 632: 631: 630: 627:inhalant abuse 620: 615: 610: 605: 600: 595: 590: 585: 580: 575: 505: 502: 501: 500: 496:infection and 491: 486: 479: 476: 475: 474: 471:Lubag syndrome 464: 459: 454: 449: 444: 435: 426: 421: 416: 411: 401: 391: 386: 381: 378:Pick's disease 371: 364: 359: 342: 339: 334: 331: 330: 329: 322: 319: 313: 308: 303: 297: 292: 287: 282: 277: 272: 262: 255: 253:shuffling gait 249: 212:motor symptoms 203: 200: 172:motor symptoms 150:is a clinical 143: 142: 141: 140: 134: 129: 124: 119: 114: 97: 92: 87: 80: 76: 75: 62: 56: 55: 47: 46: 38: 26: 9: 6: 4: 3: 2: 4414: 4403: 4400: 4398: 4395: 4393: 4390: 4389: 4387: 4371: 4367: 4366: 4362: 4361: 4358: 4354: 4347: 4343: 4342: 4338: 4336: 4332: 4331: 4327: 4325: 4321: 4320: 4316: 4312: 4310: 4306: 4302: 4298: 4297: 4293: 4289: 4287: 4283: 4282: 4278: 4274: 4273: 4270: 4265: 4261: 4245: 4243: 4240: 4239: 4237: 4234: 4231: 4228: 4226: 4223: 4222: 4218: 4212: 4209: 4206: 4202: 4198: 4195: 4192: 4188: 4184: 4180: 4177: 4176: 4174: 4170: 4164: 4161: 4159: 4156: 4154: 4151: 4149: 4146: 4144: 4141: 4139: 4136: 4134: 4131: 4129: 4126: 4124: 4121: 4119: 4116: 4114: 4111: 4109: 4106: 4104: 4101: 4099: 4096: 4094: 4091: 4089: 4086: 4084: 4081: 4079: 4076: 4074: 4071: 4070: 4068: 4066: 4062: 4051: 4047: 4044: 4041: 4037: 4033: 4029: 4026: 4023: 4019: 4016: 4015: 4013: 4011: 4008: 4004: 3998: 3995: 3993: 3990: 3988: 3985: 3984: 3982: 3980: 3977: 3973: 3967: 3964: 3962: 3959: 3957: 3954: 3953: 3951: 3949: 3946: 3942: 3936: 3933: 3931: 3928: 3926: 3923: 3921: 3918: 3916: 3913: 3911: 3908: 3907:Non-ergoline: 3905: 3904: 3901: 3898: 3896: 3893: 3891: 3888: 3886: 3883: 3881: 3880:Bromocriptine 3878: 3875: 3874: 3872: 3870: 3867: 3863: 3856: 3852: 3849: 3846: 3845:+foscarbodipa 3842: 3839: 3836: 3832: 3828: 3824: 3821: 3820: 3818: 3816: 3813: 3809: 3806: 3804: 3803:Dopaminergics 3800: 3795: 3791: 3784: 3779: 3777: 3772: 3770: 3765: 3764: 3761: 3739: 3736: 3735: 3734: 3731: 3730: 3723: 3720: 3718: 3715: 3714: 3713: 3710: 3708: 3705: 3701: 3698: 3696: 3693: 3689: 3686: 3684: 3681: 3679: 3676: 3675: 3673: 3671: 3668: 3666: 3663: 3661: 3658: 3656: 3653: 3651: 3648: 3647: 3646: 3643: 3641: 3638: 3637: 3636: 3634: 3630: 3629: 3624: 3621: 3619: 3616: 3614: 3611: 3610: 3609: 3607: 3603: 3602: 3600: 3598: 3594: 3588: 3585: 3583: 3580: 3579: 3577: 3575: 3571: 3568: 3566: 3562: 3559: 3555: 3545: 3542: 3540: 3537: 3535: 3532: 3530: 3527: 3525: 3524:Reye syndrome 3522: 3520: 3517: 3516: 3514: 3510: 3504: 3501: 3499: 3496: 3492: 3489: 3487: 3484: 3482: 3479: 3477: 3476:Hydrocephalus 3474: 3473: 3472: 3469: 3468: 3466: 3464: 3460: 3448: 3444: 3443: 3442: 3439: 3438: 3436: 3432: 3426: 3422: 3420: 3417: 3415: 3412: 3411: 3409: 3407: 3403: 3397: 3393: 3391: 3388: 3386: 3383: 3381: 3378: 3377: 3375: 3373: 3369: 3363: 3359: 3357: 3354: 3352: 3349: 3347: 3344: 3343: 3341: 3339: 3335: 3331: 3328: 3326: 3320: 3314: 3310: 3308: 3305: 3303: 3300: 3298: 3295: 3294: 3292: 3290: 3289:Demyelinating 3286: 3276: 3273: 3272: 3270: 3268: 3264: 3258: 3255: 3254: 3253: 3252: 3246: 3243: 3241: 3238: 3234: 3231: 3230: 3229: 3225: 3222: 3218: 3215: 3211: 3208: 3207: 3206: 3203: 3202: 3201: 3198: 3197: 3195: 3193: 3189: 3183: 3180: 3178: 3177:Restless legs 3175: 3171: 3168: 3166: 3163: 3162: 3161: 3158: 3157: 3152: 3149: 3145: 3142: 3141: 3140: 3137: 3133: 3130: 3129: 3128: 3125: 3123: 3120: 3116: 3115:Blepharospasm 3113: 3111: 3108: 3106: 3103: 3101: 3098: 3097: 3096: 3093: 3092: 3091: 3088: 3087: 3082: 3079: 3077: 3074: 3072: 3071:Hemiballismus 3069: 3067: 3064: 3060: 3057: 3056: 3055: 3052: 3048: 3045: 3044: 3043: 3040: 3036: 3033: 3031: 3028: 3026: 3023: 3022: 3021: 3018: 3017: 3016: 3013: 3012: 3010: 3008: 3003: 2999: 2996: 2994: 2990: 2987: 2985: 2980: 2976: 2966: 2963: 2961: 2958: 2954: 2951: 2950: 2949: 2946: 2945: 2943: 2941: 2936: 2928: 2925: 2924: 2923: 2922:Brain abscess 2920: 2918: 2915: 2911: 2908: 2906: 2903: 2901: 2898: 2896: 2893: 2892: 2891: 2888: 2887: 2885: 2883: 2879: 2876: 2874: 2870: 2866: 2862: 2854: 2849: 2847: 2842: 2840: 2835: 2834: 2831: 2825: 2822: 2820: 2817: 2816: 2796: 2790: 2782: 2776: 2768: 2764: 2757: 2749: 2745: 2740: 2735: 2731: 2727: 2723: 2719: 2715: 2708: 2700: 2696: 2691: 2686: 2682: 2678: 2674: 2670: 2666: 2659: 2645:on 2013-06-26 2641: 2634: 2628: 2620: 2616: 2612: 2608: 2604: 2600: 2596: 2592: 2588: 2584: 2580: 2576: 2572: 2568: 2561: 2559: 2550: 2546: 2541: 2536: 2532: 2528: 2524: 2520: 2519:J Clin Neurol 2516: 2509: 2501: 2497: 2492: 2487: 2482: 2477: 2473: 2469: 2465: 2458: 2450: 2446: 2442: 2438: 2434: 2430: 2426: 2422: 2415: 2407: 2403: 2398: 2393: 2388: 2383: 2379: 2375: 2374:BMC Neurology 2371: 2364: 2356: 2352: 2347: 2342: 2338: 2334: 2331:(4): 346–53. 2330: 2326: 2322: 2315: 2307: 2303: 2299: 2295: 2291: 2287: 2284:(6): 1133–6. 2283: 2279: 2272: 2264: 2260: 2256: 2252: 2249:: S152–S155. 2248: 2244: 2237: 2229: 2225: 2220: 2215: 2211: 2207: 2204:(4): 482–90. 2203: 2199: 2195: 2188: 2180: 2176: 2171: 2166: 2161: 2156: 2152: 2148: 2145:(12): e8247. 2144: 2140: 2136: 2132: 2125: 2117: 2113: 2109: 2105: 2101: 2097: 2092: 2087: 2083: 2079: 2075: 2068: 2060: 2056: 2052: 2048: 2044: 2040: 2036: 2032: 2028: 2024: 2020: 2013: 2005: 2001: 1996: 1991: 1987: 1983: 1979: 1975: 1971: 1967: 1963: 1956: 1948: 1944: 1940: 1936: 1932: 1928: 1924: 1920: 1916: 1912: 1908: 1901: 1893: 1889: 1884: 1879: 1875: 1871: 1867: 1863: 1859: 1855: 1851: 1844: 1836: 1832: 1828: 1824: 1820: 1816: 1812: 1808: 1801: 1794: 1788: 1780: 1776: 1771: 1766: 1761: 1756: 1752: 1748: 1744: 1737: 1729: 1725: 1721: 1717: 1710: 1703: 1695: 1691: 1686: 1681: 1677: 1673: 1669: 1665: 1661: 1654: 1646: 1642: 1639:(9): 860–71. 1638: 1634: 1627: 1619: 1615: 1611: 1607: 1602: 1597: 1593: 1589: 1585: 1578: 1570: 1566: 1561: 1556: 1551: 1546: 1542: 1538: 1534: 1527: 1519: 1515: 1510: 1505: 1500: 1495: 1491: 1487: 1483: 1476: 1474: 1465: 1461: 1456: 1451: 1447: 1443: 1440:(2): 204–12. 1439: 1435: 1431: 1424: 1422: 1413: 1409: 1405: 1401: 1397: 1393: 1389: 1385: 1378: 1370: 1366: 1362: 1358: 1355:(6): 323–34. 1354: 1350: 1343: 1335: 1331: 1327: 1323: 1319: 1315: 1308: 1300: 1296: 1291: 1286: 1282: 1278: 1275:(1): 88–100. 1274: 1270: 1266: 1259: 1251: 1247: 1242: 1237: 1233: 1229: 1225: 1221: 1217: 1210: 1202: 1198: 1194: 1190: 1186: 1182: 1178: 1171: 1163: 1157: 1153: 1149: 1142: 1140: 1138: 1136: 1134: 1132: 1130: 1128: 1126: 1124: 1122: 1120: 1118: 1116: 1114: 1112: 1110: 1108: 1106: 1104: 1102: 1100: 1098: 1096: 1094: 1092: 1090: 1088: 1086: 1084: 1082: 1080: 1078: 1069: 1065: 1060: 1055: 1051: 1047: 1042: 1037: 1033: 1029: 1025: 1018: 1010: 1006: 1002: 998: 994: 990: 983: 968: 962: 958: 957: 949: 947: 939: 934: 930: 925: 920: 916: 912: 909:(3): 145–55. 908: 904: 900: 893: 891: 882: 876: 872: 865: 863: 861: 856: 849: 847: 843: 839: 827: 824: 822: 821:Tetrabenazine 819: 816: 813: 811: 808: 806: 803: 801: 798: 797: 796: 793: 791: 787: 783: 779: 775: 771: 767: 763: 759: 755: 754:thioxanthenes 751: 747: 743: 739: 729: 718: 715: 712: 709: 707: 704: 702: 699: 696: 692: 688: 687:basal ganglia 684: 680: 676: 673: 670: 669: 660: 657: 654: 651: 648: 645: 642:(subcortical 641: 638: 637: 628: 624: 621: 619: 616: 614: 611: 609: 606: 604: 601: 599: 596: 594: 591: 589: 586: 584: 581: 579: 576: 574: 571: 570: 569: 566: 564: 560: 558: 554: 550: 549:basal ganglia 546: 542: 538: 534: 529: 527: 523: 519: 515: 511: 499: 495: 492: 490: 487: 485: 482: 481: 472: 468: 465: 463: 460: 458: 455: 453: 450: 448: 445: 443: 439: 436: 434: 430: 427: 425: 422: 420: 417: 415: 412: 409: 405: 402: 399: 395: 392: 390: 387: 385: 382: 379: 375: 372: 370:is not clear. 369: 365: 363: 360: 358: 355: 354: 353: 351: 347: 338: 327: 323: 320: 317: 314: 312: 309: 307: 304: 302: 298: 296: 293: 291: 288: 286: 283: 281: 278: 276: 273: 271: 267: 263: 260: 256: 254: 250: 247: 244: 243: 242: 240: 237:Parkinsonism 235: 233: 229: 225: 221: 217: 213: 209: 199: 197: 193: 189: 185: 181: 177: 173: 169: 165: 161: 157: 153: 149: 139: 135: 133: 130: 128: 125: 123: 120: 118: 115: 113: 109: 105: 101: 98: 96: 93: 91: 88: 86: 83: 82: 81: 77: 72: 66: 63: 61: 57: 53: 48: 43: 35: 30: 19: 4363: 4339: 4328: 4313: 4290: 4275: 4143:Procyclidine 4128:Orphenadrine 4073:Benzatropine 4050:+foslevodopa 4046:Foscarbidopa 3906: 3876: 3827:+benserazide 3732: 3631: 3604: 3565:Degenerative 3302:Inflammatory 3249: 3182:Stiff-person 3020:Parkinsonism 3019: 2993:Degenerative 2890:Encephalitis 2873:Inflammation 2863:, primarily 2799:. Retrieved 2789: 2775:cite journal 2766: 2762: 2756: 2721: 2717: 2707: 2675:(3): 360–5. 2672: 2668: 2658: 2647:. Retrieved 2640:the original 2627: 2574: 2570: 2522: 2518: 2508: 2471: 2467: 2457: 2424: 2420: 2414: 2377: 2373: 2363: 2328: 2324: 2314: 2281: 2277: 2271: 2246: 2242: 2236: 2201: 2197: 2187: 2142: 2138: 2131:Gendelman HE 2124: 2081: 2077: 2067: 2026: 2022: 2012: 1969: 1965: 1955: 1917:(1): 43–47. 1914: 1910: 1900: 1857: 1853: 1843: 1813:(5): 616–9. 1810: 1806: 1800: 1787: 1750: 1746: 1736: 1719: 1715: 1702: 1667: 1663: 1653: 1636: 1632: 1626: 1591: 1587: 1577: 1540: 1536: 1526: 1489: 1485: 1437: 1433: 1387: 1383: 1377: 1352: 1348: 1342: 1320:(2): 65–71. 1317: 1313: 1307: 1272: 1268: 1258: 1223: 1219: 1209: 1184: 1180: 1170: 1147: 1031: 1027: 1017: 995:(6): 412–9. 992: 988: 982: 970:. Retrieved 955: 936: 906: 902: 870: 842:Agent Orange 835: 794: 746:perphenazine 735: 727: 689:(especially 629:: "huffing") 567: 563:Agent Orange 561: 541:dopaminergic 530: 507: 344: 341:Neurological 336: 259:bradykinesia 236: 224:bradykinesia 205: 160:bradykinesia 148:Parkinsonism 147: 146: 102:, including 45:Parkinsonism 29: 18:Parkinsonian 4365:MedlinePlus 4232:from market 4191:rimantadine 4179:Adamantanes 4163:Tropatepine 4148:Profenamine 4138:Piroheptine 4036:+melevodopa 4018:Benserazide 3920:Pramipexole 3910:Apomorphine 3885:Cabergoline 3866:DA receptor 3841:Foslevodopa 3717:Fazio–Londe 3557:Both/either 3351:Generalised 3210:Early-onset 3205:Alzheimer's 2940:spinal cord 1588:Neurol Clin 826:Cinnarizine 782:cinnarizine 780:medication 770:haloperidol 758:flupentixol 557:Lewy bodies 316:Cogwheeling 4397:Geriatrics 4386:Categories 4341:DiseasesDB 4183:amantadine 4153:Tigloidine 4108:Etanautine 4098:Dexetimide 4083:Bornaprine 4032:+carbidopa 4010:inhibitors 3987:Entacapone 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Index

Parkinsonian
Parkinson's disease

Specialty
Neurology
Edit this on Wikidata
Parkinson's disease
Dementia with Lewy bodies
Parkinson's disease dementia
Other neurodegenerative disorders
multiple system atrophy
progressive supranuclear palsy
corticobasal degeneration
Drugs
Toxins
Metabolic disease
Dural arteriovenous fistula
arteriovenous malformation
syndrome
tremor
bradykinesia
rigidity
postural instability
motor symptoms
Parkinson's disease
dementia with Lewy bodies
Parkinson's disease dementia
neurodegenerative
toxins
metabolic diseases

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