565:
66:
25:
186:
314:. In 1965, he became professor of Biochemistry at the University of Amsterdam and head of the section for Medical Enzymology and Molecular Biology of the Biochemistry Department. From 1972 to 1980 Borst was also part-time Director of the Institute of Animal Physiology of the University of Amsterdam where he set up the first Unit for Molecular Biology on the Biology Campus.
849:
Xu G, Chapman JR, Brandsma I, Yuan J, Mistrik M, Bouwman P, Bartkova J, Gogola E, Warmerdam D, Barazas M, Jaspers JE, Watanabe K, Pieterse M, Kersbergen A, Sol W, Celie PH, Schouten PC, van den Broek B, Salman A, Nieuwland M, de Rink I, de Ronde J, Jalink K, Boulton SJ, Chen J, van Gent DC, Bartek J,
771:
Smit JJM, Schinkel AH, Oude
Elferink RPJ, Groen AK, Wagenaar E, Van Deemter L, Mol CAAM, Ottenhof R, Van der Lugt NMT, Van Roon M, Van der Valk MA, Offerhaus GJA, Berns AJM, Borst P. Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and
841:
Rottenberg S, Jaspers J, Kersbergen A, Van der Burg E, Nygren AOH, Zander S, Derksen PW, de Bruin M, Zevenhoven J, Lau A, Boulter R, Cranston A, O'Connor MJ, Martin NMB, Borst P, Jonkers J. High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with
321:
where he became director of research and in 1987 also chairman. He retained an honorary professorship at the
University of Amsterdam. After his mandatory retirement in 1999, Borst became a staff member and continued running his lab, studying mechanisms of chemotherapy resistance in cancer cells, the
865:
Jansen RS, Duijst S, Mahakena S, Sommer D, Szeri F, Varadi A, Plomp A, Bergen AA, Oude
Elferink RP, Borst P, van de Wetering K. ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation-brief report. Arterioscler
803:
van Luenen H, Farris C, Jan S, Genest P-A, Tripathi P, Velds A, Kerkhoven RM, Nieuwland M, Haydock A, Ramasamy G, Vainio S, Heidebrecht T, Perrakis A, Pagie L, van
Steensel B, Myler P, Borst P. Glucosylated hydroxymethyluracil (DNA base J) prevents transcriptional read-through in Leishmania. Cell.
837:
Rottenberg S, Nygren AOH, Pajic M, Van
Leeuwen FWB, Van der Heijden I, Van de Wetering K, Liu X, de Visser KE, Gilhuijs KG, Van Tellingen O, Schouten JP, Jonkers J, Borst P. Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer.
759:
Schinkel AH, Smit JJM, Van
Tellingen O, Beijnen JH, Wagenaar E, Van Deemter L, Mol CAAM, Van der Valk MA, Robanus-Maandag EC, Te Riele HPJ, Berns AJM, Borst P. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs.
665:
The MRP (ABCC) family of drug transporters has multiple members (36) (37) (38). Identification of new endogenous substrates for MRP3 (ABCC3) and BCRP (ABCG2): phyto-estrogen conjugates (39) (40); MRP4 (ABCC4): prostaglandins (41); and MRP5 (ABCC5): N-lactoyl-amino acids, a novel metabolites of
857:
Planells-Cases R, Lutter D, Guyader C, Gerhards NM, Ullrich F, Elger DA, Kucukosmanoglu A, Xu G, Voss FK, Reincke SM, Stauber T, Blomen VA, Vis DJ, Wessels LF, Brummelkamp TR, Borst P, Rottenberg S, Jentsch TJ. Subunit composition of VRAC channels determines substrate specificity and cellular
845:
Rottenberg S, Vollebergh MA, de Hoon B, de Ronde J, Schouten PC, Kersbergen A, Zander SA, Pajic M, Jaspers JE, Jonkers M, Loden M, Sol W, van der Burg E, Wesseling J, Gillet JP, Gottesman MM, Gribnau J, Wessels L, Linn SC, Jonkers J, Borst P. Impact of intertumoral heterogeneity on predicting
767:
Schinkel AH, Mayer U, Wagenaar E, Mol CAAM, Van
Deemter L, Smit JJM, Van der Valk MA, Voordouw AC, Spits H, Van Tellingen O, Zijlmans JMJM, Fibbe WE, Borst P. Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. Proc Natl Acad Sci U S A.
652:
Identification of the first ABC-transporter in a protozoal parasite, Leishmania, the PGP-A gene (now LtpgpA). This transporter gene is associated with arsenite resistance and is surrounded by direct and inverted DNA repeats facilitating gene amplification (27) (28) (29). This was the first
333:
experiments; as a director of the cancer institute he regularly reported on advances in cancer research/treatment in the press and on radio/TV; he was a member of the
Innovation Platform, a small thinktank of the Dutch prime-minister; and for 23 years he wrote a monthly column in the prime
707:
Heyting C, Meijlink FC, Verbeet MP, Sanders JP, Bos JL, Borst P. Fine structure of the 21S ribosomal RNA region on yeast mitochondria DNA. I. Construction of the physical map and localization of the cistron for the 21S mitochondrial ribosomal RNA. Molecular & General
Genetics.
799:
Yu Z, Genest PA, ter Riet B, Sweeney K, DiPaolo C, Kieft R, Christodoulou E, Perrakis A, Simmons JM, Hausinger RP, Van Luenen HGAM, Rigden DJ, Sabatini R, Borst P. The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase. Nucleic Acids Res.
830:
Jansen R AR, Merkx R, Fish A, Mahakena S, Bleijerveld O, Altelaar M, IJlst L, Wanders R, Borst P and Van de
Wetering JK. N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids. Proc Natl Acad Sci U S A.
815:
Wijnholds J, Mol CAAM, Van Deemter L, De Haas M, Scheffer GL, Baas F, Beijnen JH, Scheper RJ, Hatse S, De Clercq E, Balzarini J, Borst P. Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleoside analogs. Proc Natl Acad Sci U S A.
678:
Pseudoxanthoma elasticum, an inborn error of calcification due to absence of MRP6 (ABCC6) in the liver, is caused by low plasma pyrophosphate (PPi). MRP6 mediates ATP export from cells and this is rapidly converted into PPi (binding calcium) by ectonucleotidases (50,
826:
Reid G, Wielinga P, Zelcer N, Van der Heijden I, Kuil A, De Haas M, Wijnholds J, Borst P. The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci U S A.
853:
Tkac J, Xu G, Adhikary H, Young JT, Gallo D, Escribano-Diaz C, Krietsch J, Orthwein A, Munro M, Sol W, Al-Hakim A, Lin ZY, Jonkers J, Borst P, Brown GW, Gingras AC, Rottenberg S, Masson JY, Durocher D. HELB Is a Feedback Inhibitor of DNA End Resection. Mol Cell.
861:
Jansen RS, Kucukosmanoglu A, de Haas M, Sapthu S, Otero JA, Hegman IE, Bergen AA, Gorgels TG, Borst P, van de Wetering K. ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release. Proc Natl Acad Sci U S A.
763:
Mayer U, Wagenaar E, Beijnen JH, Smit JW, Meijer DKF, Van Asperen J, Borst P, Schinkel AH. Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr1a P-glycoprotein. Br J Pharmacol.
618:
Mammalian mitochondrial DNA consists of small duplex circles (3) that are identical in sequence, as proven by quantitative DNA renaturation experiments (4). It follows that the bulk of mitochondrial proteins is not encoded in mitochondrial DNA, but must be
807:
Kool M, De Haas M, Scheffer GL, Scheper RJ, Van Eijk MJT, Juijn JA, Baas F, Borst P. Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologs of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res.
811:
Kool M, Van der Linden M, De Haas M, Scheffer GL, De Vree JML, Smith AJ, Jansen G, Peters GJ, Ponne N, Scheper RJ, Oude Elferink RPJ, Baas F, Borst P. MRP3, an organic anion transporter able to transport anti-cancer drugs. Proc Natl Acad Sci U S A.
789:
Van Leeuwen F, Taylor MC, Mondragon A, Moreau H, Gibson W, Kieft R, Borst P. Beta-D-Glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres. Proc Natl Acad Sci U S A.
785:
Gommers-Ampt JH, Van Leeuwen F, de Beer AL, Vliegenthart JF, Dizdaroglu M, Kowalak JA, Crain PF, Borst P. beta-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. brucei. Cell.
834:
Jansen RS, Mahakena S, de Haas M, Borst P, van de Wetering K. ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs. J Biol Chem. 2015;290(51):30429-40.
775:
Crozatier M, Van der Ploeg LH, Johnson PJ, Gommers-Ampt J, Borst P. Structure of a telomeric expression site for variant specific surface antigens in Trypanosoma brucei. Molecular & Biochemical Parasitology.
819:
Van de Wetering K, Feddema W, Helms JB, Brouwers JF, Borst P. Targeted metabolomics identifies glucuronides of dietary phytoestrogens as a major class of MRP3 substrates in vivo. Gastroenterol. 2009;137:1725-35.
721:
Bernards A, Van der Ploeg LH, Frasch AC, Borst P, Boothroyd JC, Coleman S, Cross GA. Activation of trypanosome surface glycoprotein genes involves a duplication-transposition leading to an altered 3' end. Cell.
728:
Van der Ploeg LH, Liu AY, Michels PA, De Lange TD, Borst P, Majumder HK, Weber H, Veeneman GH, Van Boom J. RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes. NAR.
718:
Boothroyd JC, Cross GA, Hoeijmakers JH, Borst P. A variant surface glycoprotein of Trypanosoma brucei synthesized with a C-terminal hydrophobic 'tail' absent from purified glycoprotein. Nature. 1980;288:624-6.
2146:
822:
Krumpochova P, Sapthu S, Brouwers JF, De Haas M, de Vos R, Borst P, Van de Wetering K. Transportomics: screening for substrates of ABC transporters in body fluids using vesicular transport assays. FASEB J.
796:
Van Luenen HGAM, Kieft R, Mussmann R, Engstler M, ter Riet B, Borst P. Trypanosomes change their transferrin receptor expression to allow effective uptake of host transferrin. Mol Microbiol. 2005;58:151-65.
738:
Kooter JM, Borst P. Alpha-amanitin-insensitive transcription of variant surface glycoprotein genes provides further evidence for discontinuous transcription in trypanosomes. NuclAcids Res. 1984;12:9457-72.
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Bos JL, Osinga KA, Van der Horst G, Hecht NB, Tabak HF, Van Ommen GJ, Borst P. Splice point sequence and transcripts of the intervening sequence in the mitochondrial 21S ribosomal RNA gene of yeast. Cell.
659:
Variation in the transferrin receptor allows African trypanosomes to efficiently take up transferrin in a range of mammals, notwithstanding the rapid evolution of mammalian transferrins (32) (33).
94:
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Ouellette M, Hettema E, Wust D, Fase-Fowler F, Borst P. Direct and inverted DNA repeats associated with P-glycoprotein gene amplification in drug resistant Leishmania. EMBO J. 1991;10:1009-16.
2151:
271:) is emeritus professor of clinical biochemistry and molecular biology at the University of Amsterdam (UVA), and until 1999 director of research and chairman of the board of directors of the
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De Lange T, Borst P. Genomic environment of the expression-linked extra copies of genes for surface antigens of Trypanosoma brucei resembles the end of a chromosome. Nature. 1982;299:451-3.
689:
Borst P. Hydrogen transport and transport metabolites. In: Karlsson P, editor. Springer Verlag. Funktionelle und morphologische Organisation der Zelle; 1963. Heidelberg1963. p. 137-62.
615:
Bacteriophage RNA replicase keeps the template and daughter strand separated during RNA synthesis; duplex RNA is not an intermediate in RNA synthesis, but an isolation artifact (2).
2136:
756:
Heymans HS, Schutgens RB, Tan R, van den Bosch H, Borst P. Severe plasmalogen deficiency in tissues of infants without peroxisomes (Zellweger syndrome). Nature. 1983;306:69-70.
653:
representative of the ABCC class of transporters. Later Ouellette showed in his own lab that LtpgpA is an arsenite-GSH transporter involved in antimony resistance in patients.
2126:
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Hoeijmakers JH, Frasch AC, Bernards A, Borst P, Cross GAM. Novel expression-linked copies of the genes for variant surface antigens in trypanosomes. Nature. 1980;284:78-80.
646:
Protective physiological functions of drug-transporting P-glycoproteins (ABCB1), i.a. in the blood-brain barrier (23) and in the gut (oral availability of drugs) (24) (25).
502:
378:
1991 – 2004 Member of the Scientific Committee of the Foundation Louis Jeantet, Genève, de jury of the Louis Jeantet Prize (since 1997 President of the jury), Switzerland
329:
Borst contributed to discussions about science and science policy in the Netherlands: In the seventies he was spokesman for science in the rather virulent discussions on
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Development of ethidium-agarose electrophoresis (5) (for the separation of DNA topoisomers); proof that linear DNA molecules move like snakes through the gel (5).
2166:
2116:
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Laird PW, Kooter JM, Loosbroek N, Borst P. Mature mRNAs of Trypanosoma brucei possess a 5' cap acquired by discontinuous RNA synthesis. NAR. 1985;13:4253-66.
426:
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Opperdoes FR, Borst P. Localization of nine glycolytic enzymes in a microbody-like organelle in Trypanosoma brucei: the glycosome. FEBS Lett. 1977;80:360-4.
1441:
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The first mouse tumor model suitable for studying mechanisms of primary and acquired resistance against drugs used to treat cancer patients (44) (45) (46).
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Growth and contraction of chromosome ends, the telomeres (18); trypanosome telomeres end in repeats of (GGGTTA)n (19) later also found in human telomeres.
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Borst P, Weissmann C. Replication of viral RNA, 8. Studies on the enzymatic mechanism of replication of MS2 RNA. Proc Natl Acad Sci U S A. 1965;54:982-7.
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Piet Borst studied medicine in Amsterdam from 1952 to 1958 and completed his internships in 1961-1962. He received his PhD for an investigation of tumor
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De Lange T, Michels PA, Veerman HJ, Cornelissen AW, Borst P. Many trypanosome messenger RNAs share a common 5' terminal sequence. NAR. 1984;12:3777-90.
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Bitter W, Gerrits H, Kieft R, Borst P. The role of transferrin-receptor variation in the host range of Trypanosoma brucei. Nature. 1998;391:499-502.
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Identification of new factors inhibiting DNA end resection, REV7 (47) and HELB (48), contributing to drug resistance in a mouse mammary tumor model.
1951:
382:
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Ouellette M, Borst P. Drug resistance and P-glycoprotein gene amplification in the protozoan parasite Leishmania. Res Microbiol. 1991;142:737-46.
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The glycosome, a new peroxisome-like organelle that contains the glycolytic enzyme system in trypanosomes and related uni-cellular parasites (6).
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Jonkers J, Borst P, Rottenberg S. REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature. 2015;521(7553):541-4.
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The malate-aspartate shuttle (“Borst cycle”), a new major route for the transport of reducing equivalents from cytosol to mitochondria (1).
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Identification of the Volume-Regulation Anion Channel, as a contributor to uptake of Pt-based anti-cancer drugs in cells (49).
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Van der Ploeg LH, Cornelissen AW, Michels PA, Borst P. Chromosome rearrangements in Trypanosoma brucei. Cell. 1984;39:213-21.
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Van Bruggen EF, Borst P, Ruttenberg GJ, Gruber M, Kroon AM. Circular mitochondrial DNA. Biochim Biophys Acta. 1966;119:437-9.
544:
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2007 The distinguished Service Award, awarded at the Miami Nature Biotechnology Winter Symposium, Miami Beach, Florida, USA.
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Biosynthesis of base J (34) and identification of J as an essential termination signal in RNA synthesis in Leishmania (35).
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Bernards A, Michels PA, Lincke CR, Borst P. Growth of chromosome ends in multiplying trypanosomes. Nature. 1983;303:592-7.
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Proof that the Mdr2/MDR3 (ABCB4) P-glycoprotein is a phosphatidylcholine translocator, essential for bile formation (26).
148:
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Introduction of PFG electrophoresis for the separation of chromosome-sized DNA molecules of several protozoa (20) (21).
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1999 – 2005 Member of the Scientific Advisory Board of the Zentrum für Molekulare Biologie, Heidelberg, Germany
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Van der Ploeg LHT, Liu AYC, Borst P. Structure of the growing telomeres of Trypanosomes. Cell. 1984;36:459-68.
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Van der Ploeg LH, Cornelissen AW, Barry JD, Borst P. Chromosomes of kinetoplastida. EMBO J. 1984;3:3109-15.
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The first prenatal test for the Zellweger syndrome, a deadly inborn error of peroxisome biosynthesis (22).
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1992 Dr. H.P. Heineken prize for biochemistry and biophysics of the Royal Netherlands Academy of Sciences
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Kooter JM, De Lange T, Borst P. Discontinuous synthesis of mRNA in trypanosomes. EMBO J. 1984;3:2387-92.
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1986 – 1990 Member of the Scientific Advisory Board of the Basel Institute for Immunology, Switzerland
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Transsplicing as an essential step in the synthesis of all trypanosome mRNAs (13) (14) (15) (16, 17).
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2010 Gebroeders Bruinsma Erepenning van de Nederlandse Vereniging tegen de Kwakzalverij, Amsterdam.
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2000 Hamilton Fairley Award for Clinical Research, European Society for Medical Oncology, Hamburg.
408:
2004 – 2008 Chairman of the Scientific Advisory Board of the Fritz-Lipmann Institut, Jena, Germany
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A DNA transposition mechanism for antigenic variation in African trypanosomes (9) (10) (11) (12).
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Borst P, Ruttenberg GJ. Renaturation of mitochondrial DNA. Biochim Biophys Acta. 1966;114:645-7.
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279:(NKI-AVL). He continued to work at the NKI-AVL as a staff member and group leader until 2016.
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8:
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1999 Medal of the University of Amsterdam for exceptional contributions to the university
462:
1984 Paul-Ehrlich und Ludwig-Darmstaedter Prize, Germany (shared with Prof. George Cross)
846:
chemotherapy response of BRCA1-deficient mammary tumors. Cancer Res. 2012;72(9):2350-61.
701:
Aaij C, Borst P. The gel electrophoresis of DNA. Biochim Biophys Acta. 1972;269:192-200.
141:
1808:
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1986:
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physiological functions of drug transporters and the biosynthesis and function of DNA
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1998:
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2000 – 2005 Member of the External Scientific and Strategic Committee (CEOSS) of the
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326:, a new base in DNA that had been discovered in trypanosomes by his research group.
1939:
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1990 Gold medal of the Genootschap voor Natuur-, Genees- en Heelkunde in Amsterdam
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2016:
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Mitochondrial genes of the yeast Saccharomyces may contain introns (7) (8).
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1984 F.M.V.V. Prize of the Dutch Federation of Medical Scientific Societies
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2010:
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J, a new base in the DNA of trypanosomes and related parasites (30) (31).
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resistance to Pt-based anti-cancer drugs. EMBO J. 2015;34(24):2993-3008.
1974:
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1826:
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1990 Dr. G. Wander award of the Wander Foundation in Bern, Switzerland
2147:
Members of the Koninklijke Hollandsche Maatschappij der Wetenschappen
1802:
298:
He then moved to New York City, where he worked with fellow post-doc
268:
468:
1989 Howard Taylor Ricketts Award of the University of Chicago, USA
405:
2000 – 2006 Member Supervisory Board Schering A.G., Berlin, Germany
1372:
932:
Lasker-Koshland Special Achievement Award in Medical Science 2023
480:
1992 Gold medal of the Robert Koch Foundation in Cologne, Germany
1077:
946:. Royal Netherlands Academy of Arts and Sciences. Archived from
459:
1981 Royal Dutch/Shell-prize for the Life Sciences (Netherlands)
348:
323:
104:
from the article and its talk page, especially if potentially
2152:
Members of the Royal Netherlands Academy of Arts and Sciences
503:
Lasker-Koshland Special Achievement Award in Medical Science
483:
1993 Prof.dr P. Muntendam prize of the Dutch Cancer Society
425:
2013 – 2016 Member of the Scientific Advisory Board of the
418:
2005 – 2012 Member of the Board of Scientific Governors of
411:
2005 – 2012 Member of the Scientific Advisory Board of the
388:
1994 – 2000 Member of the Scientific Advisory Board of the
381:
1992 – 1998 Member of the Scientific Advisory Board of the
371:
1986 – 1993 Member of the Scientific Advisory Board of the
362:
361:
1985 – 1991 Member of the Scientific Advisory Board of the
317:
In 1983 Borst moved to the Netherlands Cancer Institute -
554:
264:
1018:. American Academy of Arts and Sciences. Archived from
842:
platinum drugs. ProcNatl AcadSciUSA. 2008;105:17079-84.
2137:
Foreign associates of the National Academy of Sciences
550:
2009 Fellow of the European Academy of Cancer Sciences
427:
European Research Institute for the Biology of Ageing
2127:
Fellows of the American Academy of Arts and Sciences
486:
1999 Silver Medal of merit of the City of Amsterdam
16:
Dutch biologist, molecular biologist and biochemist
911:"Hoogleraar Piet Borst ontvangt Britse ridderorde"
521:1983 De Hollandsche Maatschappij der Wetenschappen
2078:
383:Swiss Institute for Experimental Cancer Research
2122:Commanders of the Order of the Netherlands Lion
365:in Heidelberg, Germany. (1988 – 1991 President)
1000:. National Academy of Sciences. Archived from
517:Royal Netherlands Academy of Arts and Sciences
2167:Academic staff of the University of Amsterdam
2117:Commanders of the Order of the British Empire
1388:
1063:
891:(in Dutch). NRC Handelsblad. 20 November 1999
838:Proc Natl Acad Sci U S A. 2007;104:12117-22.
666:mammals (42), and glutamate-conjugates (43).
349:Major international organisational functions
53:Learn how and when to remove these messages
1395:
1381:
1070:
1056:
543:1995 International Honorary Member of the
509:
402:, Paris, France (since 2004 also chairman)
97:about living persons that is unsourced or
373:Research Institute of Molecular Pathology
247:Learn how and when to remove this message
229:Learn how and when to remove this message
168:Learn how and when to remove this message
590:by adding descriptive text and removing
772:to liver disease. Cell. 1993;75:451-62.
2079:
555:Discoveries of Borst and collaborators
312:New York University School of Medicine
1376:
1051:
545:American Academy of Arts and Sciences
433:
2132:Foreign members of the Royal Society
866:Thromb Vasc Biol. 2014;34(9):1985-9.
558:
453:
358:Council (1982 – 1984 vice-president)
179:
59:
18:
1402:
982:. Academia Europaea. Archived from
429:(ERIBA), Groningen, The Netherlands
13:
14:
2183:
1361:Roger Makins, 1st Baron Sherfield
1030:
34:This article has multiple issues.
913:(in Dutch). Trouw. 18 April 2007
885:"'Wetenschapsjunk' werkt verder"
563:
277:Antoni van Leeuwenhoekziekenhuis
184:
64:
23:
964:. Royal Society. Archived from
683:
445:2007 Honorary Commander of the
319:Antoni van Leeuwenhoek Hospital
42:or discuss these issues on the
2162:University of Amsterdam alumni
1236:Michael Augustine Raftery
1008:
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536:1991 Foreign Associate of the
420:The Scripps Research Institute
385:(ISREC), Lausanne, Switzerland
341:His doctoral students include
1:
2172:Winners of the Heineken Prize
870:
441:Order of the Netherlands Lion
390:Imperial Cancer Research Fund
306:in the lab of Nobel laureate
2142:Members of Academia Europaea
538:National Academy of Sciences
273:Netherlands Cancer Institute
75:biography of a living person
7:
1411:Biochemistry and Biophysics
540:, Washington, United States
524:1986 Foreign Member of the
447:Order of the British Empire
354:1978 – 1984 Elected member
204:. The specific problem is:
102:must be removed immediately
10:
2188:
2107:Dutch molecular biologists
1219:Thomas Nelson Marsham
2157:Scientists from Amsterdam
1961:
1902:
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1093:
413:London Research Institute
282:
1298:Gordon Richard Wray
415:, London, United Kingdom
334:intellectual daily, the
1242:Vulimiri Ramalingaswami
592:less pertinent examples
510:Membership of academics
439:1999 Commander in the
1708:BirdLife International
1689:Environmental Sciences
1325:Antonio Garcia-Bellido
1267:Charles J. M. Stirling
862:2013;110(50):20206-11.
760:Cell. 1994;77:491-502.
267:(born 5 July 1934, in
206:written like a résumé.
89:Please help by adding
1247:Peter Richardson
1287:Elizabeth Warrington
1044:at the KNAW website.
831:2015;112(21):6601-6.
827:2003;100(16):9244-9.
211:improve this article
200:to meet Knowledge's
95:Contentious material
1127:Dennis Chapman
968:on 26 October 2016.
804:2012;150(5):909-21.
588:improve the article
1320:Albert Eschenmoser
1282:David Wallace
1262:Michael Smith
1168:Martin Fleischmann
1121:Geoffrey Burnstock
823:2012;26(2):738-47.
434:Royal distinctions
302:on replication of
2112:Dutch oncologists
2097:Dutch biochemists
2074:
2073:
1903:Cognitive Science
1370:
1369:
1183:John Rodney Guest
1173:C. Robin Ganellin
1004:on 24 March 2019.
986:on 28 March 2019.
764:1996;119:1038-44.
729:1982;10:3591-604.
609:
608:
532:Academia Europaea
454:Scientific awards
400:Institute Pasteur
375:, Vienna, Austria
300:Charles Weissmann
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1101:Roy M. Anderson
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1345:Vivian Fuchs
1340:Shosaku Numa
1314:
1296:
1292:Allan Wilson
1272:John Sulston
1234:
1217:
1188:Gabriel Horn
1125:
1106:John Argyris
1020:the original
1010:
1002:the original
992:
984:the original
980:"Piet Borst"
974:
966:the original
962:"Piet Borst"
956:
948:the original
944:"Piet Borst"
938:
927:
915:. Retrieved
905:
893:. Retrieved
888:
879:
684:Publications
597:
586:Please help
574:may contain
573:
392:, Londen, GB
340:
328:
316:
308:Severo Ochoa
297:
291:(Supervisor
289:mitochondria
286:
261:
260:
258:
243:
225:
216:
209:Please help
205:
194:
164:
158:October 2017
155:
145:
138:
131:
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117:"Piet Borst"
112:
101:
84:verification
77:
50:
43:
37:
36:Please help
33:
2087:1934 births
1863:McKitterick
1809:Van der Wee
1277:Jean Thomas
1178:Adrian Gill
1153:John Dowell
1116:Alec Broers
213:if you can.
2081:Categories
2017:Van Golden
1934:McClelland
1750:Brunekreef
1679:Deisseroth
1601:Montagnier
1442:Van Deenen
1354:Statute 12
1315:Piet Borst
1203:Allen Kerr
1111:Ian Axford
998:"P. Borst"
871:References
580:irrelevant
262:Piet Borst
219:April 2017
128:newspapers
39:improve it
2041:Struycken
2029:B. Visser
2023:Koelewijn
1981:C. Visser
1946:Kanwisher
1922:Tomasello
1839:Schilling
1726:Harremoës
1673:Carmeliet
1631:Blackburn
1583:Lauterbur
1464:Reichardt
1454:Weissmann
1042:Biography
619:imported.
576:excessive
269:Amsterdam
80:citations
45:talk page
1910:Anderson
1833:De Vries
1786:Le Quéré
1762:Laurance
1732:Thompson
1696:Lovelock
1649:Steinman
1613:Marshall
1589:Van Rood
1576:Medicine
1566:Stillman
1542:De Lange
1524:Jeffreys
1488:Berridge
1418:Chargaff
1085:elected
600:May 2022
582:examples
275:and the
195:require
106:libelous
2035:Manders
1993:Martens
1969:Verhoef
1952:Zatorre
1916:Dehaene
1887:McNeill
1875:Assmann
1845:Le Goff
1821:Oberman
1796:History
1720:Ehrlich
1702:Branica
1667:Jackson
1661:Alitalo
1655:Clevers
1607:De Wied
1595:Moncada
1530:Szostak
1506:Rothman
1436:De Duve
1424:Brachet
1308:Foreign
1094:Fellows
1087:in 1986
1081:of the
1079:Fellows
310:at the
197:cleanup
142:scholar
2067:(2020)
2061:(2018)
2055:(2016)
2049:(2014)
2043:(2012)
2037:(2010)
2031:(2008)
2025:(2006)
2019:(2004)
2013:(2002)
2007:(2000)
2005:Geelen
2001:(1998)
1995:(1996)
1989:(1994)
1987:Röling
1983:(1992)
1977:(1990)
1971:(1988)
1954:(2020)
1948:(2018)
1942:(2016)
1940:Spelke
1936:(2014)
1930:(2012)
1928:Duncan
1924:(2010)
1918:(2008)
1912:(2006)
1895:(2020)
1893:Daston
1889:(2018)
1883:(2016)
1881:Herrin
1877:(2014)
1871:(2012)
1869:Parker
1865:(2010)
1859:(2008)
1857:Israel
1853:(2006)
1847:(2004)
1841:(2002)
1835:(2000)
1829:(1998)
1823:(1996)
1817:(1994)
1811:(1992)
1805:(1990)
1788:(2020)
1782:(2018)
1780:Hebert
1776:(2016)
1770:(2014)
1764:(2012)
1758:(2010)
1756:Tilman
1752:(2008)
1746:(2006)
1740:(2004)
1734:(2002)
1728:(2000)
1722:(1998)
1716:(1996)
1710:(1994)
1704:(1992)
1698:(1990)
1681:(2020)
1675:(2018)
1669:(2016)
1663:(2014)
1657:(2012)
1651:(2010)
1645:(2008)
1639:(2006)
1633:(2004)
1627:(2002)
1625:Selkoe
1621:(2000)
1619:Kandel
1615:(1998)
1609:(1996)
1603:(1994)
1597:(1992)
1591:(1990)
1585:(1989)
1568:(2020)
1562:(2018)
1560:Zhuang
1556:(2016)
1554:Doudna
1550:(2014)
1548:Dobson
1544:(2012)
1538:(2010)
1532:(2008)
1526:(2006)
1520:(2004)
1514:(2002)
1508:(2000)
1502:(1998)
1500:Pawson
1496:(1996)
1490:(1994)
1484:(1992)
1478:(1990)
1472:(1988)
1466:(1985)
1462:&
1460:Julesz
1456:(1982)
1450:(1979)
1444:(1976)
1438:(1973)
1432:(1970)
1430:Chance
1426:(1967)
1420:(1964)
1363:
1037:Resume
917:21 May
895:21 May
501:2023
324:Base J
283:Career
144:
137:
130:
123:
115:
1851:Mokyr
1827:Ozouf
1815:Brown
1738:Levin
1536:Hartl
1512:Tsien
1494:Nurse
1482:Borst
1476:Leder
854:2016.
530:1989
515:1978
449:(CBE)
422:, USA
149:JSTOR
135:books
73:This
2065:Blom
1774:Mace
1744:Pimm
1714:Daly
1643:Peto
1637:King
1518:Fire
1470:Cech
1448:Klug
919:2020
897:2020
679:51).
363:EMBL
356:EMBO
121:news
82:for
2011:Mik
1975:Bot
1962:Art
1803:Gay
889:NRC
578:or
295:).
265:CBE
2083::
887:.
345:.
338:.
93:.
48:.
1396:e
1389:t
1382:v
1071:e
1064:t
1057:v
921:.
899:.
602:)
598:(
594:.
584:.
505:.
250:)
244:(
232:)
226:(
221:)
217:(
171:)
165:(
160:)
156:(
146:·
139:·
132:·
125:·
108:.
87:.
55:)
51:(
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