318:
58:
1496:. The reactivation of polyomavirus in the kidneys and urinary tract causes the shedding of infected cells, virions, and/or viral proteins in the urine. This allows urine cytology to examine these cells, which if there is polyomavirus inclusion of the nucleus, is diagnostic of infection. Also as the urine of an infected individual will contain virions and/or viral DNA, quantitation of the viral load can be done through PCR. This is also true for the blood.
390:
251:
33:
526:, present oncogenic potential. Several mechanisms have been described for regulating the transition from early to late gene expression, including the involvement of the LT protein in repressing the early promoter, the expression of un-terminated late mRNAs with extensions complementary to early mRNA, and the expression of regulatory
1503:
Tissue staining using a monoclonal antibody against MCV T antigen shows utility in differentiating Merkel cell carcinoma from other small, round cell tumors. Blood tests to detect MCV antibodies have been developed and show that infection with the virus is widespread although Merkel cell carcinoma
1499:
Renal biopsy can also be used if the two methods just described are inconclusive or if the specific viral load for the renal tissue is desired. Similarly to the urine cytology, the renal cells are examined under light microscopy for polyomavirus inclusion of the nucleus, as well as cell lysis and
1479:
The diagnosis of polyomavirus almost always occurs after the primary infection as it is either asymptomatic or sub-clinical. Antibody assays are commonly used to detect presence of antibodies against individual viruses. Competition assays are frequently needed to distinguish among highly similar
844:
Description of additional viruses is ongoing. These include the sea otter polyomavirus 1 and Alpaca polyomavirus
Another virus is the giant panda polyomavirus 1. Another virus has been described from sigmodontine rodents. Another - tree shrew polyomavirus 1 - has been described in the tree shrew.
563:
plays a key role in regulating the viral life cycle by binding to the viral origin of DNA replication where it promotes DNA synthesis. Also as the polyomavirus relies on the host cell machinery to replicate the host cell needs to be in s-phase for this to begin. Due to this, large T-antigen also
473:
The details of transit to the nucleus are not clear and may vary among individual polyomaviruses. It has been frequently reported that an intact, albeit distorted, virion particle is released from the endoplasmic reticulum into the cell cytoplasm, where the genome is released from the capsid,
521:
LT does not. LT induces DNA replication from the viral genome's non-coding control region (NCCR), after which expression of the early mRNA is reduced and expression of the late mRNA, which encodes the viral capsid proteins, begins. As these interactions begin, the LTs belonging to several
1399:
All the polyomaviruses are highly common childhood and young adult infections. Most of these infections appear to cause little or no symptoms. These viruses are probably lifelong persistent among almost all adults. Diseases caused by human polyomavirus infections are most common among
568:(pRB) family, and stimulating cell growth pathways by binding cellular DNA, ATPase-helicase, DNA polymerase α association, and binding of transcription preinitiation complex factors. This abnormal stimulation of the cell cycle is a powerful force for oncogenic transformation.
1387:
contains only the four human viruses shown in the above table. The Alpha and Beta groups contain viruses that infect a variety of mammals. The Gamma group contains the avian viruses. Clinically significant disease associations are shown only where causality is expected.
1548:, after whom it was once called "SE polyoma". The term "polyoma" refers to the viruses' ability to produce multiple (poly-) tumors (-oma) under certain conditions. The name has been criticized as a "meatless linguistic sandwich" ("meatless" because both
1483:
In cases of progressive multifocal leucoencephalopathy (PML), a cross-reactive antibody to SV40 T antigen (commonly Pab419) is used to stain tissues directly for the presence of JC virus T antigen. PCR can be used on a biopsy of the tissue or
404:, many water-mediated, is shown at the binding surface by orange lines, with participating protein residues shown as sticks. Mutations of the two residues shown in cyan at the bottom of the figure can significantly affect pathogenicity. From
1512:
The JC virus offers a promising genetic marker for human evolution and migration. It is carried by 70–90 percent of humans and is usually transmitted from parents to offspring. This method does not appear to be reliable for tracing the
752:
The current ICTV classification system recognises six genera and 117 species, of which five could not be assigned a genus. This system retains the distinction between avian and mammalian viruses, grouping the avian subset into the genus
564:
modulates cellular signaling pathways to stimulate progression of the cell cycle by binding to a number of cellular control proteins. This is achieved by a two prong attack of inhibiting tumor suppressing genes p53 and members of the
1552:
in "polyoma" are affixes) giving little insight into the viruses' biology; in fact, subsequent research has found that most polyomaviruses rarely cause clinically significant disease in their host organisms under natural conditions.
675:. It is essential for proliferation in the viruses that express it and is thought to be involved in regulating the viral life cycle, particularly replication and viral exit from the host cell, but the exact mechanisms are unclear.
530:. Expression of the late genes results in accumulation of the viral capsid proteins in the host cell cytoplasm. Capsid components enter the nucleus in order to encapsidate new viral genomic DNA. New virions may be assembled in
1450:
without causing disease, but can cause cancer in rodents under laboratory conditions. In the 1950s and early 1960s, well over 100 million people may have been exposed to SV40 due to previously undetected SV40 contamination of
683:
The polyomaviruses are members of group I (dsDNA viruses). The classification of polyomaviruses has been the subject of several proposed revisions as new members of the group are discovered. Formerly, polyomaviruses and
3501:
Gonçalves Motta Maia F, Marciel de Souza W, Sabino-Santos G, Jorge
Fumagalli M, Modha S, Ramiro Murcia P, Tadeu Moraes Figueiredo L (2018). "A novel polyomavirus in sigmodontine rodents from São Paulo State, Brazil".
1491:
There are three main diagnostic techniques used for the diagnosis of the reactivation of polyomavirus in polyomavirus nephropathy (PVN): urine cytology, quantification of the viral load in both urine and blood, and a
862:(TSV) is distantly related to MCV. Two viruses—HPyV6 and HPyV7—are most closely related to KI and WU viruses, while HPyV9 is most closely related to the African green monkey-derived lymphotropic polyomavirus (LPV).
3371:
Siqueira JD, Ng TF, Miller M, Li L, Deng X, Dodd E, Batac F, Delwart E (July 2017). "Endemic infection of stranded southern sea otters (Enhydra lutris nereis) with novel parvovirus, polyomavirus, and adenovirus".
3673:
Shuda M, Arora R, Kwun HJ, Feng H, Sarid R, Fernández-Figueras MT, Tolstov Y, Gjoerup O, Mansukhani MM, Swerdlow SH, Chaudhary PM, Kirkwood JM, Nalesnik MA, Kant JA, Weiss LM, Moore PS, Chang Y (September 2009).
2766:
Pallas DC, Shahrik LK, Martin BL, Jaspers S, Miller TB, Brautigan DL, Roberts TM (January 1990). "Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A".
853:
Most polyomaviruses do not infect humans. Of the polyomaviruses cataloged as of 2017, a total of 14 were known with human hosts. However, some polyomaviruses are associated with human disease, particularly in
509:, when the host cell's genome is replicated - because host cell DNA replication machinery is needed for viral genome replication. The precise mechanism of this dysregulation depends on the virus; for example,
4986:
Drews K, Bashir T, Dörries K (January 2000). "Quantification of human polyomavirus JC in brain tissue and cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy by competitive PCR".
454:. However, in general virus-cell interactions are mediated by commonly occurring molecules on the cell surface, and therefore are likely not a major contributor to individual viruses' observed cell-type
816:
830:
809:
3596:
Gheit T, Dutta S, Oliver J, Robitaille A, Hampras S, Combes JD, McKay-Chopin S, Le Calvez-Kelm F, Fenske N, Cherpelis B, Giuliano AR, Franceschi S, McKay J, Rollison DE, Tommasino M (2017).
837:
1471:, accurate detection is often confounded by high levels of cross-reactivity for SV40 with widespread human polyomaviruses. Most virologists dismiss SV40 as a cause for human cancers.
222:, have been identified in humans to a lesser extent. Most of these viruses are very common and typically asymptomatic in most human populations studied. BK virus is associated with
4157:
Ho J, Jedrych JJ, Feng H, Natalie AA, Grandinetti L, Mirvish E, Crespo MM, Yadav D, Fasanella KE, Proksell S, Kuan SF, Pastrana DV, Buck CB, Shuda Y, Moore PS, Chang Y (May 2015).
4469:
Gheit, Tarik; Dutta, Sankhadeep; Oliver, Javier; Robitaille, Alexis; Hampras, Shalaka; Combes, Jean-Damien; McKay-Chopin, Sandrine; Calvez-Kelm, Florence Le; Fenske, Neil (2017).
4906:
Drachenberg CB, Hirsch HH, Ramos E, Papadimitriou JC (December 2005). "Polyomavirus disease in renal transplantation: review of pathological findings and diagnostic methods".
823:
325:, a human polyomavirus. The early region is shown on the left and contains the TAg (tumor antigen) proteins; the late region is on the right and contains the capsid proteins.
1657:
4021:
Padgett BL, Walker DL, ZuRhein GM, Eckroade RJ, Dessel BH (June 1971). "Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy".
5707:
1810:
Gossai A, Waterboer T, Nelson HH, Michel A, Willhauck-Fleckenstein M, Farzan SF, Hoen AG, Christensen BC, Kelsey KT, Marsit CJ, Pawlita M, Karagas MR (January 2016).
575:
protein is also able to activate several cellular pathways that stimulate cell proliferation. Polyomavirus small T antigens commonly target protein phosphatase 2A (
2709:"The T/t common exon of simian virus 40, JC, and BK polyomavirus T antigens can functionally replace the J-domain of the Escherichia coli DnaJ molecular chaperone"
1455:, prompting concern about the possibility that the virus might cause disease in humans. Although it has been reported as present in some human cancers, including
1556:
Dozens of polyomaviruses have been identified and sequenced as of 2017, infecting mainly birds and mammals. Two polyomaviruses are known to infect fish, the
1391:
Antibodies to the monkey lymphotropic polyomavirus have been detected in humans suggesting that this virus - or a closely related virus - can infect humans.
783:
353:
start sites. Additional genes and other variations on this theme are present in some viruses: for example, rodent polyomaviruses have a third protein called
310:, which is capable of self-assembly into a closed icosahedron; each pentamer of VP1 is associated with one molecule of one of the other two capsid proteins,
180:
745:
5613:"Concurrence of Iridovirus, Polyomavirus, and a Unique Member of a New Group of Fish Papillomaviruses in Lymphocystis Disease-Affected Gilthead Sea Bream"
8004:
4420:
Lim ES, Reyes A, Antonio M, Saha D, Ikumapayi UN, Adeyemi M, Stine OC, Skelton R, Brennan DC, Mkakosya RS, Manary MJ, Gordon JI, Wang D (February 2013).
790:
776:
710:(that is, genetically related groups): the SV40 clade, the avian clade, and the murine polyomavirus clade. A subsequent proposed reclassification by the
187:
173:
337:
regions called the early and late regions due to the time during infection in which they are transcribed. Each region is transcribed by the host cell's
8478:
797:
769:
194:
166:
9055:
8577:
7772:
6051:
859:
8874:
8542:
8485:
8457:
8429:
8099:
7783:
7714:
6974:
6967:
6058:
6016:
6009:
2912:"Merkel cell polyomavirus small T antigen controls viral replication and oncoprotein expression by targeting the cellular ubiquitin ligase SCFFbw7"
5261:
Carter JJ, Paulson KG, Wipf GC, Miranda D, Madeleine MM, Johnson LG, Lemos BD, Lee S, Warcola AH, Iyer JG, Nghiem P, Galloway DA (November 2009).
3547:"Detection and genome characterization of two novel papillomaviruses and a novel polyomavirus in tree shrew (Tupaia belangeri chinensis) in China"
3113:"Infection by agnoprotein-negative mutants of polyomavirus JC and SV40 results in the release of virions that are mostly deficient in DNA content"
9615:
9069:
8923:
8450:
8443:
7263:
6079:
6065:
6023:
5163:"Human Merkel cell polyomavirus infection II. MCV is a common human infection that can be detected by conformational capsid epitope immunoassays"
2605:
White MK, Gordon J, Reiss K, Del Valle L, Croul S, Giordano A, Darbinyan A, Khalili K (December 2005). "Human polyomaviruses and brain tumors".
9161:
9112:
9062:
9041:
8492:
6002:
5700:
5112:
Busam KJ, Jungbluth AA, Rekthman N, Coit D, Pulitzer M, Bini J, Arora R, Hanson NC, Tassello JA, Frosina D, Moore P, Chang Y (September 2009).
711:
3227:"IARC Working Group on the Evaluation of Carcinogenic Risk to Humans. Malaria and Some Polyomaviruses (SV40, BK, JC, and Merkel Cell Viruses)"
2301:"Structural and Functional Analysis of Murine Polyomavirus Capsid Proteins Establish the Determinants of Ligand Recognition and Pathogenicity"
534:. The mechanism of viral release from the host cell varies among polyomaviruses; some express proteins that facilitate cell exit, such as the
9628:
8881:
7954:
7947:
3010:"Interaction of polyomavirus internal protein VP2 with the major capsid protein VP1 and implications for participation of VP2 in viral entry"
895:
218:
are primarily mammals and birds. As of 2024, there are eight recognized genera. 14 species are known to infect humans, while others, such as
1514:
5114:"Merkel cell polyomavirus expression in merkel cell carcinomas and its absence in combined tumors and pulmonary neuroendocrine carcinomas"
3162:
Saribas AS, Coric P, Hamazaspyan A, Davis W, Axman R, White MK, Abou-Gharbia M, Childers W, Condra JH, Bouaziz S, Safak M (October 2016).
2812:"The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation"
2554:
Rotondo JC, Bononi I, Puozzo A, Govoni M, Foschi V, Lanza G, Gafà R, Gaboriaud P, Touzé FA, Selvatici R, Martini F, Tognon M (July 2017).
688:, which share many structural features but have very different genomic organizations, were classified together in the now-obsolete family
466:- a behavior unique among known non-enveloped viruses - where the viral capsid structure is likely to be disrupted by action of host cell
4422:"Discovery of STL polyomavirus, a polyomavirus of ancestral recombinant origin that encodes a unique T antigen by alternative splicing"
3986:
Gardner SD, Field AM, Coleman DV, Hulme B (June 1971). "New human papovavirus (B.K.) isolated from urine after renal transplantation".
1421:
1147:
231:
4108:
Nguyen KD, Lee EE, Yue Y, Stork J, Pock L, North JP, Vandergriff T, Cockerell C, Hosler GA, Pastrana DV, Buck CB, Wang RC (May 2017).
594:
regulating both cellular and viral oncoproteins. Unlike for SV40, the MCV small T antigen directly transforms rodent cells in vitro.
5693:
3676:"Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors"
647:, and in the interior of the capsid each pentamer is associated with one molecule of either VP2 or VP3. Some polyomaviruses, such as
2650:"Polyomavirus-associated Trichodysplasia spinulosa involves hyperproliferation, pRB phosphorylation and upregulation of p16 and p21"
438:
to sialylated glycans on the cell surface. In some particular viruses, additional cell-surface interactions occur; for example, the
261:, colored such that areas of the surface closer to the interior center appear blue and areas further away appear red. Rendered from
9602:
4206:
Toptan T, Yousem SA, Ho J, Matsushima Y, Stabile LP, Fernández-Figueras MT, Bhargava R, Ryo A, Moore PS, Chang Y (February 2016).
5335:
Gross L (June 1953). "A filterable agent, recovered from Ak leukemic extracts, causing salivary gland carcinomas in C3H mice".
957:
4962:
858:
individuals. MCV is highly divergent from the other human polyomaviruses and is most closely related to murine polyomavirus.
3939:"Identification of a novel polyomavirus in a pancreatic transplant recipient with retinal blindness and vasculitic myopathy"
663:
is a small multifunctional phospho-protein found in the late coding part of the genome of some polyomaviruses, most notably
345:
containing multiple genes. The early region usually codes for two proteins, the small and large tumor antigens, produced by
9674:
4056:
Allander T, Andreasson K, Gupta S, Bjerkner A, Bogdanovic G, Persson MA, Dalianis T, Ramqvist T, Andersson B (April 2007).
5378:
Stewart SE, Eddy BE, Borgese N (June 1958). "Neoplasms in mice inoculated with a tumor agent carried in tissue culture".
2556:"Merkel Cell Carcinomas Arising in Autoimmune Disease Affected Patients Treated with Biologic Drugs, Including Anti-TNF"
5319:
3874:
Korup S, Rietscher J, Calvignac-Spencer S, Trusch F, Hofmann J, Moens U, Sauer I, Voigt S, Schmuck R, Ehlers B (2013).
2851:
Watanabe G, Howe A, Lee RJ, Albanese C, Shu IW, Karnezis AN, Zon L, Kyriakis J, Rundell K, Pestell RG (November 1996).
2507:"Comparisons between Murine Polyomavirus and Simian Virus 40 Show Significant Differences in Small T Antigen Function"
2481:
1541:
633:
400:. GT1a is shown in yellow and the VP1 monomer with a white surface and a blue protein backbone. A complex network of
311:
307:
258:
3297:
Johne R, Buck CB, Allander T, Atwood WJ, Garcea RL, Imperiale MJ, Major EO, Ramqvist T, Norkin LC (September 2011).
9641:
9633:
2204:
Gaynor AM, Nissen MD, Whiley DM, Mackay IM, Lambert SB, Wu G, Brennan DC, Storch GA, Sloots TP, Wang D (May 2007).
1580:
Moens U, Calvignac-Spencer S, Lauber C, Ramqvist T, Feltkamp MC, Daugherty MD, Verschoor EJ, Ehlers B (June 2017).
1488:
to amplify the polyomavirus DNA. This allows not only the detection of polyomavirus but also which sub type it is.
3450:
Qi D, Shan T, Liu Z, Deng X, Zhang Z, Bi W, Owens JR, Feng F, Zheng L, Huang F, Delwart E, Hou R, Zhang W (2017).
587:
small T antigen encodes a unique domain, called the LT-stabilization domain (LSD), that binds to and inhibits the
3725:"Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient"
3415:
Dela Cruz FN, Li L, Delwart E, Pesavento PA (2017). "A novel pulmonary polyomavirus in alpacas (Vicugna pacos)".
5161:
Tolstov YL, Pastrana DV, Feng H, Becker JC, Jenkins FJ, Moschos S, Chang Y, Buck CB, Moore PS (September 2009).
2158:
Salunke DM, Caspar DL, Garcea RL (September 1986). "Self-assembly of purified polyomavirus capsid protein VP1".
583:, the mitogen-activated protein kinase (MAPK) pathway, and the stress-activated protein kinase (SAPK) pathway.
478:
concentration in the cytoplasm. Both expression of viral genes and replication of the viral genome occur in the
5464:"Glycosaminoglycans and sialylated glycans sequentially facilitate Merkel cell polyomavirus infectious entry"
4807:"Thirty-five year mortality following receipt of SV40- contaminated polio vaccine during the neonatal period"
2961:"Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator"
2352:"Glycosaminoglycans and sialylated glycans sequentially facilitate Merkel cell polyomavirus infectious entry"
4762:
Gazdar AF, Butel JS, Carbone M (December 2002). "SV40 and human tumours: myth, association or causality?".
349:. The late region contains the three capsid structural proteins VP1, VP2, and VP3, produced by alternative
57:
5564:"Genome Sequence of a Fish-Associated Polyomavirus, Black Sea Bass (Centropristis striata) Polyomavirus 1"
3827:"A novel human polyomavirus closely related to the african green monkey-derived lymphotropic polyomavirus"
7493:
5023:
3776:"The trichodysplasia spinulosa-associated polyomavirus: virological background and clinical implications"
3064:"Merkel cell polyomavirus and two previously unknown polyomaviruses are chronically shed from human skin"
467:
9237:
8742:
7816:
3248:
Pérez-Losada M, Christensen RG, McClellan DA, Adams BJ, Viscidi RP, Demma JC, Crandall KA (June 2006).
651:, do not encode or express VP3. The capsid proteins are expressed from the late region of the genome.
9646:
3825:
Scuda N, Hofmann J, Calvignac-Spencer S, Ruprecht K, Liman P, Kühn J, Hengel H, Ehlers B (May 2011).
3723:
van der
Meijden E, Janssens RW, Lauber C, Bouwes Bavinck JN, Gorbalenya AE, Feltkamp MC (July 2010).
2648:
Kazem S, van der
Meijden E, Wang RC, Rosenberg AS, Pope E, Benoit T, Fleckman P, Feltkamp MC (2014).
1468:
973:
1691:
Calvignac-Spencer S, Feltkamp MC, Daugherty MD, Moens U, Ramqvist T, Johne R, Ehlers B (June 2016).
9554:
5716:
2271:
922:
648:
629:
584:
523:
435:
334:
5063:
Randhawa PS, Vats A, Zygmunt D, Swalsky P, Scantlebury V, Shapiro R, Finkelstein S (August 2002).
4645:
Egli A, Infanti L, Dumoulin A, Buser A, Samaridis J, Stebler C, Gosert R, Hirsch HH (March 2009).
3648:
865:
A fourteenth virus has been described. Lyon IARC polyomavirus is related to raccoon polyomavirus.
9679:
9669:
5024:"Polyomavirus infection of renal allograft recipients: from latent infection to manifest disease"
5022:
Nickeleit V, Hirsch HH, Binet IF, Gudat F, Prince O, Dalquen P, Thiel G, Mihatsch MJ (May 1999).
4805:
Carroll-Pankhurst C, Engels EA, Strickler HD, Goedert JJ, Wagner J, Mortimer EA (November 2001).
4255:
Siebrasse EA, Reyes A, Lim ES, Zhao G, Mkakosya RS, Manary MJ, Gordon JI, Wang D (October 2012).
1058:
365:
has an additional capsid protein VP4; some examples have an additional regulatory protein called
358:
3500:
3164:"Emerging From the Unknown: Structural and Functional Features of Agnoprotein of Polyomaviruses"
9516:
4354:
565:
350:
2206:"Identification of a novel polyomavirus from patients with acute respiratory tract infections"
1504:
patients have exceptionally higher antibody responses than asymptomatically infected persons.
9620:
5611:
López-Bueno A, Mavian C, Labella AM, Castro D, Borrego JJ, Alcami A, Alejo A (October 2016).
5065:"Quantitation of viral DNA in renal allograft tissue from patients with BK virus nephropathy"
4942:
1500:
viral partials in the extra cellular fluid. The viral load as before is also measure by PCR.
1112:
1025:
463:
378:
4647:"Prevalence of polyomavirus BK and JC infection and replication in 400 healthy blood donors"
2555:
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5263:"Association of Merkel cell polyomavirus-specific antibodies with Merkel cell carcinoma"
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2300:
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2040:
2013:
1986:
1962:"BK polyoma virus infection and renal disease in non-renal solid organ transplantation"
1961:
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1811:
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1606:
1581:
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938:
613:
239:
5000:
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Poulin DL, DeCaprio JA (September 2006). "Is there a role for SV40 in human cancer?".
4357:, Isa P, Phan TG, Martínez MA, de la Luz Sanchez M, Contreras JF, Santos-Preciado JI,
4034:
3999:
3876:"Identification of a novel human polyomavirus in organs of the gastrointestinal tract"
3545:
Liu P, Qiu Y, Xing C, Zhou JH, Yang WH, Wang Q, Li JY, Han X, Zhang YZ, Ge XY (2019).
3452:"A novel polyomavirus from the nasal cavity of a giant panda (Ailuropoda melanoleuca)"
2618:
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4627:
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4502:
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4335:
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4139:
4110:"Human polyomavirus 6 and 7 are associated with pruritic and dyskeratotic dermatoses"
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762:
447:
406:
342:
338:
263:
235:
159:
5364:
5098:
4889:
4159:"Human polyomavirus 7-associated pruritic rash and viremia in transplant recipients"
3811:
3531:
3401:
2634:
2187:
9568:
8967:
8895:
8788:
8363:
8305:
8268:
7997:
7728:
7686:
7634:
7597:
7567:
7528:
7382:
7308:
7165:
6487:
6450:
6424:
6382:
6183:
6173:
5988:
5840:
5811:
5685:
5632:
5624:
5583:
5575:
5534:
5530:
5526:
5485:
5475:
5434:
5426:
5387:
5344:
5282:
5274:
5233:
5223:
5182:
5174:
5133:
5125:
5076:
5035:
4996:
4950:
4915:
4867:
4826:
4818:
4791:
4771:
4736:
4698:
4658:
4617:
4578:
4541:
4537:
4533:
4492:
4482:
4441:
4433:
4392:
4382:
4325:
4317:
4276:
4268:
4227:
4219:
4178:
4170:
4129:
4121:
4077:
4069:
4030:
3995:
3958:
3950:
3905:
3895:
3846:
3838:
3789:
3746:
3736:
3695:
3687:
3619:
3609:
3568:
3558:
3511:
3473:
3463:
3424:
3381:
3318:
3310:
3269:
3261:
3183:
3175:
3134:
3124:
3083:
3075:
3029:
3021:
2980:
2972:
2931:
2923:
2882:
2872:
2823:
2796:
2776:
2738:
2728:
2679:
2669:
2614:
2577:
2567:
2526:
2518:
2469:
2425:
2417:
2373:
2363:
2322:
2312:
2227:
2217:
2167:
2097:
2089:
2035:
2025:
1981:
1973:
1929:
1885:
1875:
1831:
1823:
1782:
1774:
1714:
1704:
1601:
1593:
1413:
1368:
1331:
873:
The following 14 polyomaviruses with human hosts had been identified and had their
227:
4919:
4569:
Dalianis T, Hirsch HH (March 2013). "Human polyomaviruses in disease and cancer".
2572:
2030:
9539:
9427:
9298:
9133:
9081:
8994:
8950:
8939:
8777:
8629:
8570:
8394:
8115:
8045:
7933:
7916:
7851:
7448:
7403:
7124:
6631:
6413:
6324:
6244:
6140:
5480:
5228:
5210:
Pastrana DV, Tolstov YL, Becker JC, Moore PS, Chang Y, Buck CB (September 2009).
5129:
4387:
4358:
3900:
3741:
3428:
2674:
2368:
2317:
2222:
1880:
1339:
1306:
1298:
1273:
1240:
1207:
1199:
1174:
1166:
1139:
1131:
1099:
1091:
1066:
1033:
1000:
965:
930:
734:
451:
219:
118:
4949:. Advances in Experimental Medicine and Biology. Vol. 577. pp. 73–84.
4582:
4487:
4437:
4304:
Buck CB, Phan GQ, Raiji MT, Murphy PM, McDermott DH, McBride AA (October 2012).
3614:
3226:
2810:
Sontag E, Fedorov S, Kamibayashi C, Robbins D, Cobb M, Mumby M (December 1993).
2421:
2406:"How viruses use the endoplasmic reticulum for entry, replication, and assembly"
620:, while the tissue where the tumor develops is determined by the MMTV promoter.
9470:
9448:
9416:
9381:
9287:
9252:
9188:
9031:
9020:
8983:
8825:
8709:
8599:
8528:
8518:
8279:
8071:
8034:
7940:
7735:
7319:
7292:
6939:
6928:
6832:
6797:
6790:
6776:
6769:
6718:
6690:
6620:
6609:
6574:
6358:
6030:
5967:
5901:
5879:
5801:
5662:
4125:
3079:
3025:
2927:
2857:
Proceedings of the
National Academy of Sciences of the United States of America
2713:
Proceedings of the
National Academy of Sciences of the United States of America
1642:
1557:
685:
602:
443:
434:. The attachment of polyomaviruses to host cells is mediated by the binding of
370:
276:
215:
5348:
4223:
3563:
3515:
3468:
3314:
1709:
1692:
706:, and Va for "vacuolating.") The polyomaviruses were divided into three major
9663:
9438:
9333:
9319:
9147:
9140:
9119:
8960:
8909:
8902:
8766:
8662:
8640:
8613:
8589:
8549:
8506:
8471:
8464:
8436:
8422:
8415:
8316:
8252:
8223:
8202:
8181:
8170:
8150:
8082:
7904:
7873:
7862:
7840:
7707:
7574:
7560:
7550:
7517:
7441:
7393:
7336:
7329:
7176:
7076:
6950:
6864:
6846:
6825:
6811:
6711:
6648:
6598:
6520:
6498:
6471:
6434:
6336:
6303:
6151:
6129:
5929:
5912:
5890:
5868:
5790:
5779:
5579:
5562:
Peretti A, FitzGerald PC, Bliskovsky V, Pastrana DV, Buck CB (January 2015).
5391:
4702:
2877:
1537:
1452:
690:
531:
494:
401:
106:
5430:
4954:
4363:"Discovery of a novel polyomavirus in acute diarrheal samples from children"
4174:
3954:
3250:"Comparing phylogenetic codivergence between polyomaviruses and their hosts"
3129:
2093:
714:(ICTV) recommended dividing the family of Polyomaviridae into three genera:
47:
infected cell—large (blue) cell below-center-left. Urine cytology specimen.
9460:
9405:
9340:
9309:
9276:
9126:
9098:
8916:
8888:
8867:
8853:
8846:
8836:
8672:
8606:
8535:
8383:
8353:
8342:
8289:
8245:
8235:
8216:
8192:
8143:
8055:
7968:
7926:
7765:
7697:
7675:
7655:
7645:
7455:
7371:
7282:
7253:
7241:
7231:
7219:
7209:
7187:
7145:
7135:
7108:
7087:
7065:
7041:
7031:
7009:
6906:
6857:
6818:
6804:
6783:
6552:
6530:
6508:
6375:
6277:
6265:
6222:
6211:
6118:
6107:
6072:
5978:
5830:
5646:
5597:
5548:
5499:
5448:
5399:
5356:
5296:
5247:
5196:
5147:
5090:
5049:
5008:
4972:
4927:
4881:
4840:
4822:
4783:
4748:
4710:
4672:
4631:
4590:
4555:
4506:
4455:
4406:
4339:
4290:
4241:
4192:
4143:
4091:
3972:
3919:
3860:
3803:
3760:
3722:
3709:
3633:
3582:
3523:
3487:
3436:
3393:
3332:
3283:
3224:
3197:
3148:
3097:
2994:
2945:
2733:
2693:
2626:
2591:
2540:
2491:
2439:
2387:
2336:
2269:
2241:
2111:
2049:
1995:
1943:
1899:
1845:
1796:
1728:
1615:
1545:
1529:
1493:
1464:
644:
479:
291:
94:
82:
5678:
5278:
4042:
4007:
3043:
2896:
2837:
2788:
2752:
2179:
9548:
9326:
9105:
9091:
9004:
8860:
8650:
8563:
8556:
8499:
8405:
8326:
8209:
8126:
8092:
8018:
7980:
7961:
7897:
7890:
7721:
7581:
7270:
7098:
6998:
6893:
6743:
6725:
6701:
6564:
6542:
6368:
6346:
6314:
6255:
6044:
5956:
5818:
5768:
5744:
5628:
5040:
4727:
zur Hausen H (December 2003). "SV40 in human cancers--an endless tale?".
4321:
4272:
4073:
3934:
3842:
3265:
2582:
2522:
2299:
Buch MH, Liaci AM, O'Hara SD, Garcea RL, Neu U, Stehle T (October 2015).
1977:
1827:
1597:
1456:
1409:
1108:
660:
641:
535:
459:
431:
423:
366:
299:
223:
4257:"Identification of MW polyomavirus, a novel polyomavirus in human stool"
3385:
3062:
Schowalter RM, Pastrana DV, Pumphrey KA, Moyer AL, Buck CB (June 2010).
2460:
Gjoerup O, Chang Y (2010). "Update on human polyomaviruses and cancer".
1778:
9198:
9154:
9048:
8809:
7618:
7608:
7360:
6960:
6287:
6037:
5309:
4804:
4520:
Prado JC, Monezi TA, Amorim AT, Lino V, Paladino A, Boccardo E (2018).
4471:"Isolation and characterization of a novel putative human polyomavirus"
3598:"Isolation and characterization of a novel putative human polyomavirus"
2910:
Kwun HJ, Shuda M, Feng H, Camacho CJ, Moore PS, Chang Y (August 2013).
1719:
1690:
1460:
498:
482:
using host cell machinery. The early genes - comprising at minimum the
295:
40:
5212:"Quantitation of human seroresponsiveness to Merkel cell polyomavirus"
5178:
4872:
4855:
4740:
3794:
3775:
3691:
3179:
1934:
1917:
410:
267:
254:
A rendering of an icosahedral viral capsid comprising 72 pentamers of
9589:
9394:
9265:
8799:
8755:
7829:
7506:
7478:
6917:
5757:
5729:
4622:
4605:
3873:
3824:
3247:
2976:
2070:"Clonal integration of a polyomavirus in human Merkel cell carcinoma"
606:
591:
419:
389:
303:
287:
9607:
9510:
1579:
373:
control or regulatory region containing the early and late regions'
250:
9594:
9533:
5561:
4905:
4775:
4663:
4646:
4109:
3937:, Jain K, Kapoor A, Briese T, Faust PL, Lipkin WI (November 2014).
3352:. International Committee on Taxonomy of Viruses (ICTV). March 2021
1549:
1533:
1417:
1405:
668:
664:
637:
617:
527:
502:
439:
322:
2505:
Andrabi S, Hwang JH, Choe JK, Roberts TM, Schaffhausen BS (2011).
3231:
IARC Monographs on the
Evaluation of Carcinogenic Risks to Humans
2647:
2279:
IARC Monographs on the
Evaluation of Carcinogenic Risks to Humans
1564:. A total of fourteen polyomaviruses are known to infect humans.
542:. In some cases high levels of encapsidated virus result in cell
506:
475:
455:
330:
302:
in shape (T=7 symmetry). The capsid is composed of 72 pentameric
211:
5337:
Proceedings of the
Society for Experimental Biology and Medicine
458:. After binding to molecules on the cell surface, the virion is
4055:
3349:
3211:
3061:
2853:"Induction of cyclin D1 by simian virus 40 small tumor antigen"
2809:
1528:
was the first polyomavirus discovered, having been reported by
1447:
874:
579:), a key multisubunit regulator of multiple pathways including
427:
397:
329:
The genome of a typical polyomavirus codes for between 5 and 9
283:
32:
5610:
4901:
4899:
2959:
Shuda M, Kwun HJ, Feng H, Chang Y, Moore PS (September 2011).
357:
in the early region, which is extremely efficient at inducing
9581:
3780:
1812:"Seroepidemiology of Human Polyomaviruses in a US Population"
707:
588:
543:
230:
and non-renal solid organ transplant patients, JC virus with
69:
4361:, Miller S, DeRisi JL, Delwart E, Arias CF, Chiu CY (2012).
4020:
3773:
3161:
1248:
HPyV6 associated pruritic and dyskeratotic dermatosis (H6PD)
4943:"Serological Cross Reactivity between Polyomavirus Capsids"
4896:
3414:
1809:
1441:
723:
672:
610:
576:
510:
369:
expressed from the late region. The genome also contains a
362:
5209:
5111:
5062:
4604:
Van Ghelue M, Khan MT, Ehlers B, Moens U (November 2012).
4468:
3595:
2765:
5525:(2): 288–318, second and third pages, table of contents.
5419:
American
Journal of Public Health and the Nation's Health
5160:
5021:
4603:
2604:
2553:
2298:
1959:
1540:
tumors. The causative agent was identified as a virus by
628:
The polyomavirus capsid consists of one major component,
580:
539:
514:
5260:
4644:
4306:"Complete genome sequence of a tenth human polyomavirus"
4205:
3985:
3110:
2203:
1960:
Kuppachi S, Kaur D, Holanda DG, Thomas CP (April 2016).
3774:
Kazem S, van der Meijden E, Feltkamp MC (August 2013).
3299:"Taxonomical developments in the family Polyomaviridae"
3296:
2850:
2504:
5461:
3111:
Sariyer IK, Saribas AS, White MK, Safak M (May 2011).
2349:
497:
strand. These proteins serve to manipulate the host's
4519:
4254:
3932:
1918:"BK virus nephropathy in renal transplant recipients"
418:
The polyomavirus life cycle begins with entry into a
5715:
4156:
3225:
International Agency for Research on Cancer (2013).
2909:
2270:
International Agency for Research on Cancer (2013).
2068:
Feng H, Shuda M, Chang Y, Moore PS (February 2008).
1686:
1684:
1682:
1680:
1678:
4419:
4303:
2157:
2067:
5515:"Natural biology of polyomavirus middle T antigen"
5512:
5377:
5310:Elizabeth Matisoo-Smith; K. Ann Horsburgh (2012).
4985:
4761:
4352:
3672:
3370:
3007:
2958:
2706:
7018:
5462:Schowalter RM, Pastrana DV, Buck CB (July 2011).
4606:"Genome analysis of the new human polyomaviruses"
4107:
2350:Schowalter RM, Pastrana DV, Buck CB (July 2011).
1861:
1693:"A taxonomy update for the family Polyomaviridae"
1675:
1507:
860:Trichodysplasia spinulosa-associated polyomavirus
804:The following species are unassigned to a genus:
9661:
4856:"SV40 and human cancer: a review of recent data"
1862:Kean JM, Rao S, Wang M, Garcea RL (March 2009).
7684:
7380:
6422:
4722:
4720:
4684:
4682:
2455:
2453:
2451:
2449:
2199:
2197:
1416:and non-renal solid organ transplant patients,
868:
9425:
9296:
8992:
8948:
8775:
8043:
6629:
6138:
4940:
4688:
4568:
4522:"Human polyomaviruses and cancer: an overview"
4114:Journal of the American Academy of Dermatology
4103:
4101:
4058:"Identification of a third human polyomavirus"
3544:
1760:
712:International Committee on Taxonomy of Viruses
9414:
9285:
9186:
8277:
7317:
6937:
6926:
6618:
6607:
5965:
5899:
5877:
5701:
5028:Journal of the American Society of Nephrology
4597:
4562:
4248:
3449:
3204:
3057:
3055:
3053:
2399:
2397:
1582:"ICTV Virus Taxonomy Profile: Polyomaviridae"
384:
8764:
8314:
8080:
7838:
7548:
7515:
7391:
6948:
6127:
5910:
5788:
5777:
5555:
4717:
4679:
3364:
3155:
3008:Chen XS, Stehle T, Harrison SC (June 1998).
2547:
2498:
2459:
2446:
2194:
2131:
2129:
2127:
2125:
2123:
2121:
2063:
2061:
2059:
2014:"Progressive Multifocal Leukoencephalopathy"
1637:
1635:
1633:
1631:
1629:
1627:
1625:
442:is believed to require interaction with the
422:. Cellular receptors for polyomaviruses are
9403:
9307:
9274:
8834:
8351:
7695:
7643:
7369:
7133:
7029:
7007:
6116:
5976:
5412:
4208:"Survey for human polyomaviruses in cancer"
4199:
4098:
3649:"Virus Is Linked to a Powerful Skin Cancer"
3344:
3342:
3104:
2011:
1321:
1288:
1048:
1015:
8124:
7096:
5766:
5708:
5694:
5604:
5519:Microbiology and Molecular Biology Reviews
5118:The American Journal of Surgical Pathology
4798:
4726:
3050:
2410:Cold Spring Harbor Perspectives in Biology
2394:
1955:
1953:
1864:"Seroepidemiology of human polyomaviruses"
1756:
1754:
1752:
1750:
1748:
1746:
1744:
1742:
1740:
1738:
1422:progressive multifocal leukoencephalopathy
1255:
1222:
1189:
1156:
1148:Progressive multifocal leukoencephalopathy
1121:
1081:
982:
947:
912:
490:(LT) - are expressed first, from a single
232:progressive multifocal leukoencephalopathy
31:
9379:
7606:
5636:
5587:
5538:
5489:
5479:
5455:
5438:
5415:"Characteristics of the SE polyoma virus"
5286:
5237:
5227:
5186:
5137:
5080:
5039:
4871:
4830:
4662:
4621:
4545:
4496:
4486:
4445:
4396:
4386:
4329:
4280:
4231:
4182:
4133:
4081:
3962:
3909:
3899:
3867:
3850:
3793:
3750:
3740:
3699:
3623:
3613:
3589:
3572:
3562:
3477:
3467:
3322:
3290:
3273:
3187:
3138:
3128:
3087:
3033:
3001:
2984:
2935:
2886:
2876:
2827:
2742:
2732:
2683:
2673:
2581:
2571:
2530:
2429:
2403:
2377:
2367:
2326:
2316:
2231:
2221:
2118:
2101:
2056:
2039:
2029:
1985:
1933:
1911:
1909:
1889:
1879:
1835:
1786:
1718:
1708:
1622:
1605:
698:derived from three abbreviations: Pa for
9392:
9263:
9250:
8797:
8753:
7827:
7814:
7504:
5513:Gottlieb KA, Villarreal LP (June 2001).
5506:
5380:Journal of the National Cancer Institute
5267:Journal of the National Cancer Institute
4638:
4297:
4049:
3494:
3408:
3339:
2707:Kelley WL, Georgopoulos C (April 1997).
2007:
2005:
609:system where middle T is coupled to the
388:
316:
249:
8740:
4413:
4150:
4014:
3979:
3538:
2294:
2292:
2265:
2263:
2261:
2259:
2257:
2255:
2253:
2251:
2151:
1950:
1915:
1735:
848:
605:developed to study cancer, such as the
377:, transcriptional start sites, and the
245:
9662:
7491:
4755:
4346:
3933:Mishra N, Pereira M, Rhodes RH, An P,
3926:
3646:
3640:
3443:
2607:Brain Research. Brain Research Reviews
1906:
1857:
1855:
1763:"A cornucopia of human polyomaviruses"
1515:recent African origin of modern humans
958:Trichodysplasia spinulosa polyomavirus
817:Rhynchobatus djiddensis polyomavirus 1
9515:
9514:
9378:
9249:
8739:
7813:
7490:
6891:
6890:
5741:
5689:
5413:Eddy BE, Stewart SE (November 1959).
5334:
3818:
3767:
2965:The Journal of Clinical Investigation
2002:
1803:
1761:DeCaprio JA, Garcea RL (April 2013).
1404:people; disease associations include
1394:
882:
5742:
4853:
4847:
3218:
2289:
2248:
1655:
1281:HPyV7-related epithelial hyperplasia
831:Trematomus bernacchii polyomavirus 1
810:Centropristis striata polyomavirus 1
501:- dysregulating the transition from
3716:
1852:
1658:"Taxonomy browser (Polyomaviridae)"
838:Trematomus pennellii polyomavirus 1
632:, and one or two minor components,
13:
4651:The Journal of Infectious Diseases
4163:The Journal of Infectious Diseases
3943:The Journal of Infectious Diseases
1446:SV40 replicates in the kidneys of
623:
14:
9691:
5656:
4947:Polyomaviruses and Human Diseases
2619:10.1016/j.brainresrev.2005.04.007
634:minor capsid proteins VP2 and VP3
554:
549:
5082:10.1097/00007890-200208270-00009
2404:Inoue T, Tsai B (January 2013).
2272:"Introduction to Polyomaviruses"
1816:American Journal of Epidemiology
56:
5406:
5371:
5328:
5303:
5254:
5203:
5167:International Journal of Cancer
5154:
5105:
5056:
5015:
4979:
4934:
4860:International Journal of Cancer
4729:International Journal of Cancer
4513:
4462:
3680:International Journal of Cancer
3666:
3241:
2952:
2903:
2844:
2803:
2759:
2700:
2641:
2598:
2343:
1586:The Journal of General Virology
1532:in 1953 as an extract of mouse
513:LT can directly bind host cell
5531:10.1128/mmbr.65.2.288-318.2001
4989:Journal of Virological Methods
4941:Viscidi RP, Clayman B (2006).
3350:"Virus Taxonomy: 2020 Release"
3168:Journal of Cellular Physiology
1649:
1573:
1508:Use in tracing human migration
654:
290:. The genome is packaged in a
1:
5001:10.1016/S0166-0934(99)00128-7
4920:10.1016/j.humpath.2005.08.009
4035:10.1016/S0140-6736(71)91777-6
4000:10.1016/s0140-6736(71)91776-4
3647:Altman LK (18 January 2008).
2573:10.1158/1078-0432.CCR-16-2899
2474:10.1016/S0065-230X(10)06001-X
2031:10.12688/f1000research.7071.1
1567:
396:VP1 in complex with the GT1a
5481:10.1371/journal.ppat.1002161
5229:10.1371/journal.ppat.1000578
5130:10.1097/PAS.0b013e3181aa30a5
4691:Journal of Clinical Oncology
4388:10.1371/journal.pone.0049449
3901:10.1371/journal.pone.0058021
3742:10.1371/journal.ppat.1001024
3429:10.1016/j.vetmic.2017.01.005
3374:Journal of Wildlife Diseases
2829:10.1016/0092-8674(93)90533-V
2781:10.1016/0092-8674(90)90726-u
2675:10.1371/journal.pone.0108947
2369:10.1371/journal.ppat.1002161
2318:10.1371/journal.ppat.1005104
2223:10.1371/journal.ppat.0030064
2172:10.1016/0092-8674(86)90071-1
1881:10.1371/journal.ppat.1000363
1767:Nature Reviews. Microbiology
1643:"ICTV Report Polyomaviridae"
1474:
869:List of human polyomaviruses
824:Sparus aurata polyomavirus 1
7:
9675:Infectious causes of cancer
4610:Reviews in Medical Virology
4583:10.1016/j.virol.2012.12.015
4488:10.1016/j.virol.2017.03.007
4438:10.1016/j.virol.2012.12.005
3615:10.1016/j.virol.2017.03.007
2462:Advances in Cancer Research
2422:10.1101/cshperspect.a013250
904:Clinical correlate (if any)
678:
616:. There it functions as an
10:
9696:
4538:10.6061/clinics/2018/e558s
4126:10.1016/j.jaad.2016.11.035
3080:10.1016/j.chom.2010.05.006
2928:10.1016/j.chom.2013.06.008
2012:Adang L, Berger J (2015).
1916:Jamboti JS (August 2016).
1520:
1439:
522:polyomaviruses, including
385:Replication and life cycle
9523:
9458:
9436:
9388:
9374:
9259:
9245:
9236:
9175:
9079:
9029:
9018:
8981:
8937:
8823:
8786:
8749:
8735:
8690:
8660:
8638:
8627:
8587:
8516:
8403:
8392:
8381:
8340:
8303:
8266:
8233:
8190:
8179:
8168:
8113:
8069:
8032:
7978:
7914:
7871:
7860:
7849:
7823:
7809:
7753:
7673:
7632:
7595:
7537:
7526:
7500:
7486:
7477:
7429:
7358:
7306:
7280:
7251:
7229:
7207:
7185:
7174:
7163:
7122:
7085:
7074:
7063:
6996:
6915:
6904:
6900:
6886:
6757:
6735:
6699:
6688:
6681:
6596:
6562:
6540:
6518:
6496:
6485:
6459:
6448:
6411:
6400:
6356:
6334:
6312:
6301:
6275:
6253:
6242:
6231:
6220:
6209:
6171:
6149:
6105:
5954:
5888:
5866:
5828:
5799:
5755:
5751:
5737:
5728:
5349:10.3181/00379727-83-20376
4811:British Journal of Cancer
4224:10.1172/jci.insight.85562
3564:10.1186/s12985-019-1141-9
3516:10.1007/s00705-018-3913-8
3469:10.1186/s12985-017-0867-5
3315:10.1007/s00705-011-1008-x
1710:10.1007/s00705-016-2794-y
974:Trichodysplasia spinulosa
546:, releasing the virions.
155:
150:
51:
39:
30:
23:
5580:10.1128/genomeA.01476-14
4854:Shah KV (January 2007).
4703:10.1200/JCO.2005.03.7101
3026:10.1093/emboj/17.12.3233
2878:10.1073/pnas.93.23.12861
2560:Clinical Cancer Research
1107:Polyomavirus-associated
923:Merkel cell polyomavirus
649:Merkel cell polyomavirus
630:major capsid protein VP1
585:Merkel cell polyomavirus
524:Merkel cell polyomavirus
474:possibly due to the low
321:Genome structure of the
5431:10.2105/AJPH.49.11.1486
4955:10.1007/0-387-32957-9_5
3417:Veterinary Microbiology
3212:"ICTV Taxonomy Website"
3130:10.1186/1743-422X-8-255
3068:Cell Host & Microbe
2916:Cell Host & Microbe
2094:10.1126/science.1152586
1966:Clinical Kidney Journal
1469:non-Hodgkin's lymphomas
1435:
1362:Lyon IARC polyomavirus
1059:New Jersey polyomavirus
359:cellular transformation
5392:10.1093/jnci/20.6.1223
5312:DNA for Archaeologists
4823:10.1054/bjoc.2001.2065
4764:Nature Reviews. Cancer
2734:10.1073/pnas.94.8.3679
877:sequenced as of 2017:
757:. The six genera are:
415:
326:
298:in diameter, which is
282:viruses with circular
272:
4175:10.1093/infdis/jiu524
3955:10.1093/infdis/jiu250
1355:Human polyomavirus 14
1323:Human polyomavirus 11
1290:Human polyomavirus 10
1113:haemorrhagic cystitis
1050:Human polyomavirus 13
1026:Human polyomavirus 12
1017:Human polyomavirus 12
492:alternatively spliced
464:endoplasmic reticulum
392:
379:origin of replication
320:
253:
5721:virus classification
5629:10.1128/JVI.01369-16
5568:Genome Announcements
5041:10.1681/ASN.V1051080
4945:. In Ahsan N (ed.).
4322:10.1128/JVI.01690-12
4273:10.1128/JVI.01210-12
4074:10.1128/JVI.00028-07
3843:10.1128/jvi.02602-10
3504:Archives of Virology
3303:Archives of Virology
3266:10.1128/JVI.00056-06
2523:10.1128/JVI.05034-11
1697:Archives of Virology
1662:www.ncbi.nlm.nih.gov
1598:10.1099/jgv.0.000839
1536:capable of inducing
1266:Human polyomavirus 7
1257:Human polyomavirus 7
1233:Human polyomavirus 6
1224:Human polyomavirus 6
1191:Human polyomavirus 4
1158:Human polyomavirus 3
1123:Human polyomavirus 2
1083:Human polyomavirus 1
993:Human polyomavirus 9
984:Human polyomavirus 9
949:Human polyomavirus 8
914:Human polyomavirus 5
849:Human polyomaviruses
599:middle tumor antigen
355:middle tumor antigen
347:alternative splicing
306:of a protein called
246:Structure and genome
53:Virus classification
8703:Permutotetraviridae
6462:Orthopolintovirales
5937:Malacoherpesviridae
5617:Journal of Virology
5279:10.1093/jnci/djp332
4526:Clinics (Sao Paulo)
4379:2012PLoSO...749449Y
4310:Journal of Virology
4261:Journal of Virology
4062:Journal of Virology
3892:2013PLoSO...858021K
3831:Journal of Virology
3386:10.7589/2016-04-082
3254:Journal of Virology
2869:1996PNAS...9312861W
2725:1997PNAS...94.3679K
2666:2014PLoSO...9j8947K
2517:(20): 10649–10658.
2511:Journal of Virology
2086:2008Sci...319.1096F
1779:10.1038/nrmicro2992
1526:Murine polyomavirus
1486:cerebrospinal fluid
784:Epsilonpolyomavirus
573:small tumor antigen
561:large tumor antigen
519:murine polyomavirus
488:large tumor antigen
484:small tumor antigen
468:disulfide isomerase
394:Murine polyomavirus
333:, divided into two
280:double-stranded DNA
275:Polyomaviruses are
256:murine polyomavirus
181:Epsilonpolyomavirus
7021:Malgrandaviricetes
6656:Sphaerolipoviridae
6642:Matshushitaviridae
6234:Nucleocytoviricota
4532:(suppl 1): e558s.
3653:The New York Times
2080:(5866): 1096–100.
1978:10.1093/ckj/sfv143
1828:10.1093/aje/kwv155
1430:Merkel cell cancer
1395:Clinical relevance
939:Merkel cell cancer
746:Avian polyomavirus
416:
327:
273:
240:Merkel cell cancer
9657:
9656:
9517:Taxon identifiers
9508:
9507:
9504:
9503:
9500:
9499:
9496:
9495:
9492:
9491:
9488:
9487:
9484:
9483:
9480:
9479:
9370:
9369:
9366:
9365:
9362:
9361:
9358:
9357:
9354:
9353:
9350:
9349:
9232:
9231:
9228:
9227:
9224:
9223:
9220:
9219:
9216:
9215:
9212:
9211:
9208:
9207:
9178:Yunchangviricetes
9171:
9170:
9014:
9013:
8977:
8976:
8933:
8932:
8819:
8818:
8731:
8730:
8727:
8726:
8723:
8722:
8719:
8718:
8686:
8685:
8682:
8681:
8623:
8622:
8377:
8376:
8373:
8372:
8336:
8335:
8299:
8298:
8262:
8261:
8164:
8163:
8160:
8159:
8137:Carmotetraviridae
8109:
8108:
8065:
8064:
8028:
8027:
8012:Gammaflexiviridae
8005:Deltaflexiviridae
7991:Alphaflexiviridae
7884:Alphatetraviridae
7805:
7804:
7801:
7800:
7797:
7796:
7793:
7792:
7749:
7748:
7745:
7744:
7669:
7668:
7665:
7664:
7628:
7627:
7591:
7590:
7540:Chrymotiviricetes
7473:
7472:
7469:
7468:
7465:
7464:
7425:
7424:
7421:
7420:
7417:
7416:
7413:
7412:
7354:
7353:
7350:
7349:
7346:
7345:
7302:
7301:
7198:Bacilladnaviridae
7159:
7158:
7155:
7154:
7118:
7117:
7059:
7058:
7055:
7054:
7051:
7050:
6992:
6991:
6988:
6987:
6984:
6983:
6882:
6881:
6878:
6877:
6874:
6873:
6840:Portogloboviridae
6753:
6752:
6677:
6676:
6673:
6672:
6669:
6668:
6665:
6664:
6592:
6591:
6588:
6587:
6584:
6583:
6481:
6480:
6444:
6443:
6403:Preplasmiviricota
6396:
6395:
6392:
6391:
6297:
6296:
6205:
6204:
6201:
6200:
6197:
6196:
6193:
6192:
6101:
6100:
6097:
6096:
6093:
6092:
6089:
6088:
5996:Autographiviridae
5950:
5949:
5946:
5945:
5923:Alloherpesviridae
5862:
5861:
5858:
5857:
5854:
5853:
5850:
5849:
5179:10.1002/ijc.24509
4964:978-0-387-29233-5
4873:10.1002/ijc.22425
4741:10.1002/ijc.11517
4120:(5): 932–940.e3.
4029:(7712): 1257–60.
3795:10.1111/apm.12092
3692:10.1002/ijc.24510
3510:(10): 2913–2915.
3180:10.1002/jcp.25329
2566:(14): 3929–3934.
1935:10.1111/nep.12728
1562:gilthead seabream
1426:Merkel cell virus
1402:immunocompromised
1385:Deltapolyomavirus
1382:
1381:
901:Year of discovery
856:immunocompromised
791:Gammapolyomavirus
777:Deltapolyomavirus
763:Alphapolyomavirus
755:Gammapolyomavirus
720:Orthopolyomavirus
448:Merkel cell virus
343:pre-messenger RNA
339:RNA polymerase II
236:Merkel cell virus
203:
202:
188:Gammapolyomavirus
174:Deltapolyomavirus
160:Alphapolyomavirus
16:Family of viruses
9687:
9650:
9649:
9637:
9636:
9624:
9623:
9611:
9610:
9598:
9597:
9585:
9584:
9572:
9571:
9559:
9558:
9557:
9544:
9543:
9542:
9512:
9511:
9434:
9433:
9423:
9422:
9412:
9411:
9401:
9400:
9390:
9389:
9382:dsDNA-RT viruses
9376:
9375:
9305:
9304:
9294:
9293:
9283:
9282:
9272:
9271:
9261:
9260:
9253:ssRNA-RT viruses
9247:
9246:
9243:
9242:
9184:
9183:
9027:
9026:
8995:Serpentovirales
8990:
8989:
8968:Orthomyxoviridae
8946:
8945:
8896:Peribunyaviridae
8832:
8831:
8795:
8794:
8789:Chunqiuviricetes
8784:
8783:
8773:
8772:
8762:
8761:
8751:
8750:
8743:(–)ssRNA viruses
8737:
8736:
8636:
8635:
8479:Nanghoshaviridae
8401:
8400:
8390:
8389:
8364:Botourmiaviridae
8349:
8348:
8312:
8311:
8306:Howeltoviricetes
8275:
8274:
8269:Amabiliviricetes
8188:
8187:
8177:
8176:
8122:
8121:
8078:
8077:
8041:
8040:
7998:Betaflexiviridae
7869:
7868:
7858:
7857:
7847:
7846:
7836:
7835:
7825:
7824:
7817:(+)ssRNA viruses
7811:
7810:
7729:Picobirnaviridae
7693:
7692:
7687:Duplopiviricetes
7682:
7681:
7641:
7640:
7635:Vidaverviricetes
7604:
7603:
7598:Resentoviricetes
7568:Megabirnaviridae
7546:
7545:
7535:
7534:
7529:Duplornaviricota
7524:
7523:
7513:
7512:
7502:
7501:
7488:
7487:
7484:
7483:
7389:
7388:
7383:Huolimaviricetes
7378:
7377:
7367:
7366:
7315:
7314:
7309:Repensiviricetes
7183:
7182:
7172:
7171:
7166:Cressdnaviricota
7131:
7130:
7094:
7093:
7083:
7082:
7072:
7071:
7027:
7026:
7016:
7015:
7005:
7004:
6946:
6945:
6935:
6934:
6924:
6923:
6913:
6912:
6902:
6901:
6888:
6887:
6697:
6696:
6686:
6685:
6627:
6626:
6616:
6615:
6605:
6604:
6494:
6493:
6488:Tectiliviricetes
6457:
6456:
6451:Polintoviricetes
6425:Priklausovirales
6420:
6419:
6409:
6408:
6383:Marseilleviridae
6310:
6309:
6251:
6250:
6240:
6239:
6229:
6228:
6218:
6217:
6184:Papillomaviridae
6174:Zurhausenvirales
6147:
6146:
6136:
6135:
6125:
6124:
6114:
6113:
5989:Ackermannviridae
5974:
5973:
5963:
5962:
5908:
5907:
5897:
5896:
5886:
5885:
5875:
5874:
5841:Tristromaviridae
5812:Lipothrixviridae
5797:
5796:
5786:
5785:
5775:
5774:
5764:
5763:
5753:
5752:
5739:
5738:
5735:
5734:
5710:
5703:
5696:
5687:
5686:
5666:: Polyomaviridae
5651:
5650:
5640:
5608:
5602:
5601:
5591:
5574:(1): e01476-14.
5559:
5553:
5552:
5542:
5510:
5504:
5503:
5493:
5483:
5459:
5453:
5452:
5442:
5410:
5404:
5403:
5375:
5369:
5368:
5332:
5326:
5325:
5307:
5301:
5300:
5290:
5258:
5252:
5251:
5241:
5231:
5207:
5201:
5200:
5190:
5158:
5152:
5151:
5141:
5109:
5103:
5102:
5084:
5060:
5054:
5053:
5043:
5019:
5013:
5012:
4983:
4977:
4976:
4938:
4932:
4931:
4903:
4894:
4893:
4875:
4851:
4845:
4844:
4834:
4802:
4796:
4795:
4759:
4753:
4752:
4724:
4715:
4714:
4686:
4677:
4676:
4666:
4642:
4636:
4635:
4625:
4623:10.1002/rmv.1711
4601:
4595:
4594:
4566:
4560:
4559:
4549:
4517:
4511:
4510:
4500:
4490:
4466:
4460:
4459:
4449:
4417:
4411:
4410:
4400:
4390:
4350:
4344:
4343:
4333:
4301:
4295:
4294:
4284:
4252:
4246:
4245:
4235:
4203:
4197:
4196:
4186:
4154:
4148:
4147:
4137:
4105:
4096:
4095:
4085:
4053:
4047:
4046:
4018:
4012:
4011:
3994:(7712): 1253–7.
3983:
3977:
3976:
3966:
3930:
3924:
3923:
3913:
3903:
3871:
3865:
3864:
3854:
3822:
3816:
3815:
3797:
3771:
3765:
3764:
3754:
3744:
3720:
3714:
3713:
3703:
3670:
3664:
3663:
3661:
3659:
3644:
3638:
3637:
3627:
3617:
3593:
3587:
3586:
3576:
3566:
3542:
3536:
3535:
3498:
3492:
3491:
3481:
3471:
3456:Virology Journal
3447:
3441:
3440:
3412:
3406:
3405:
3368:
3362:
3361:
3359:
3357:
3346:
3337:
3336:
3326:
3294:
3288:
3287:
3277:
3245:
3239:
3238:
3222:
3216:
3215:
3208:
3202:
3201:
3191:
3159:
3153:
3152:
3142:
3132:
3117:Virology Journal
3108:
3102:
3101:
3091:
3059:
3048:
3047:
3037:
3014:The EMBO Journal
3005:
2999:
2998:
2988:
2977:10.1172/JCI46323
2956:
2950:
2949:
2939:
2907:
2901:
2900:
2890:
2880:
2848:
2842:
2841:
2831:
2807:
2801:
2800:
2763:
2757:
2756:
2746:
2736:
2704:
2698:
2697:
2687:
2677:
2645:
2639:
2638:
2602:
2596:
2595:
2585:
2575:
2551:
2545:
2544:
2534:
2502:
2496:
2495:
2457:
2444:
2443:
2433:
2401:
2392:
2391:
2381:
2371:
2347:
2341:
2340:
2330:
2320:
2311:(10): e1005104.
2296:
2287:
2286:
2276:
2267:
2246:
2245:
2235:
2225:
2201:
2192:
2191:
2155:
2149:
2148:
2146:
2144:
2133:
2116:
2115:
2105:
2065:
2054:
2053:
2043:
2033:
2009:
2000:
1999:
1989:
1957:
1948:
1947:
1937:
1913:
1904:
1903:
1893:
1883:
1859:
1850:
1849:
1839:
1807:
1801:
1800:
1790:
1758:
1733:
1732:
1722:
1712:
1688:
1673:
1672:
1670:
1668:
1653:
1647:
1646:
1639:
1620:
1619:
1609:
1592:(6): 1159–1160.
1577:
1480:polyomaviruses.
1414:renal transplant
1332:STL polyomavirus
1325:
1292:
1259:
1226:
1193:
1160:
1125:
1085:
1052:
1019:
986:
951:
916:
880:
879:
798:Zetapolyomavirus
770:Betapolyomavirus
731:Wukipolyomavirus
686:papillomaviruses
640:form the closed
413:
270:
228:renal transplant
195:Zetapolyomavirus
167:Betapolyomavirus
61:
60:
35:
21:
20:
9695:
9694:
9690:
9689:
9688:
9686:
9685:
9684:
9660:
9659:
9658:
9653:
9645:
9640:
9632:
9627:
9619:
9614:
9606:
9601:
9593:
9588:
9580:
9575:
9567:
9562:
9553:
9552:
9547:
9538:
9537:
9532:
9519:
9509:
9476:
9454:
9428:Revtraviricetes
9384:
9346:
9299:Revtraviricetes
9255:
9204:
9167:
9134:Paramyxoviridae
9082:Mononegavirales
9075:
9056:Crepuscuviridae
9010:
8973:
8951:Articulavirales
8940:Insthoviricetes
8929:
8815:
8778:Negarnaviricota
8745:
8715:
8678:
8656:
8630:Stelpaviricetes
8619:
8583:
8578:Polycipiviridae
8571:Dicistroviridae
8512:
8395:Pisoniviricetes
8369:
8332:
8295:
8258:
8229:
8156:
8116:Tolucaviricetes
8105:
8061:
8046:Amarillovirales
8024:
7974:
7934:Closteroviridae
7917:Martellivirales
7910:
7852:Kitrinoviricota
7819:
7789:
7773:Polymycoviridae
7741:
7661:
7624:
7587:
7496:
7461:
7449:Finnlakeviridae
7409:
7404:Pleolipoviridae
7342:
7298:
7276:
7247:
7225:
7203:
7151:
7125:Quintoviricetes
7114:
7047:
6980:
6896:
6870:
6749:
6731:
6661:
6632:Halopanivirales
6580:
6558:
6536:
6514:
6477:
6440:
6414:Maveriviricetes
6388:
6352:
6330:
6325:Phycodnaviridae
6293:
6271:
6245:Pokkesviricetes
6189:
6167:
6141:Papovaviricetes
6085:
6052:Rountreeviridae
5942:
5846:
5824:
5747:
5724:
5714:
5659:
5654:
5623:(19): 8768–79.
5609:
5605:
5560:
5556:
5511:
5507:
5474:(7): e1002161.
5460:
5456:
5425:(11): 1486–92.
5411:
5407:
5376:
5372:
5333:
5329:
5322:
5308:
5304:
5273:(21): 1510–22.
5259:
5255:
5222:(9): e1000578.
5208:
5204:
5159:
5155:
5110:
5106:
5069:Transplantation
5061:
5057:
5020:
5016:
4984:
4980:
4965:
4939:
4935:
4914:(12): 1245–55.
4908:Human Pathology
4904:
4897:
4852:
4848:
4803:
4799:
4760:
4756:
4725:
4718:
4697:(26): 4356–65.
4687:
4680:
4643:
4639:
4602:
4598:
4567:
4563:
4518:
4514:
4467:
4463:
4418:
4414:
4351:
4347:
4302:
4298:
4267:(19): 10321–6.
4253:
4249:
4204:
4200:
4155:
4151:
4106:
4099:
4054:
4050:
4019:
4015:
3984:
3980:
3931:
3927:
3872:
3868:
3823:
3819:
3772:
3768:
3735:(7): e1001024.
3721:
3717:
3671:
3667:
3657:
3655:
3645:
3641:
3594:
3590:
3543:
3539:
3499:
3495:
3448:
3444:
3413:
3409:
3369:
3365:
3355:
3353:
3348:
3347:
3340:
3295:
3291:
3246:
3242:
3223:
3219:
3210:
3209:
3205:
3174:(10): 2115–27.
3160:
3156:
3109:
3105:
3060:
3051:
3020:(12): 3233–40.
3006:
3002:
2957:
2953:
2908:
2904:
2863:(23): 12861–6.
2849:
2845:
2808:
2804:
2764:
2760:
2705:
2701:
2660:(10): e108947.
2646:
2642:
2603:
2599:
2552:
2548:
2503:
2499:
2484:
2458:
2447:
2402:
2395:
2362:(7): e1002161.
2348:
2344:
2297:
2290:
2274:
2268:
2249:
2202:
2195:
2156:
2152:
2142:
2140:
2135:
2134:
2119:
2066:
2057:
2010:
2003:
1958:
1951:
1914:
1907:
1874:(3): e1000363.
1860:
1853:
1808:
1804:
1759:
1736:
1689:
1676:
1666:
1664:
1654:
1650:
1641:
1640:
1623:
1578:
1574:
1570:
1523:
1510:
1477:
1444:
1438:
1397:
1299:MW polyomavirus
1200:WU polyomavirus
1167:KI polyomavirus
1132:JC polyomavirus
1092:BK polyomavirus
871:
851:
742:Avipolyomavirus
735:KI polyomavirus
681:
657:
626:
624:Capsid proteins
603:model organisms
557:
552:
532:viral factories
462:and enters the
452:heparan sulfate
405:
387:
335:transcriptional
294:of about 40-50
286:of around 5000
262:
248:
220:Simian Virus 40
210:is a family of
120:Papovaviricetes
55:
17:
12:
11:
5:
9693:
9683:
9682:
9680:Virus families
9677:
9672:
9670:Polyomaviridae
9655:
9654:
9652:
9651:
9638:
9625:
9612:
9599:
9586:
9573:
9560:
9555:Polyomaviridae
9545:
9529:
9527:
9525:Polyomaviridae
9521:
9520:
9506:
9505:
9502:
9501:
9498:
9497:
9494:
9493:
9490:
9489:
9486:
9485:
9482:
9481:
9478:
9477:
9475:
9474:
9471:Caulimoviridae
9466:
9464:
9456:
9455:
9453:
9452:
9449:Hepadnaviridae
9444:
9442:
9431:
9420:
9417:Artverviricota
9409:
9398:
9386:
9385:
9372:
9371:
9368:
9367:
9364:
9363:
9360:
9359:
9356:
9355:
9352:
9351:
9348:
9347:
9345:
9344:
9337:
9330:
9323:
9315:
9313:
9302:
9291:
9288:Artverviricota
9280:
9269:
9257:
9256:
9240:
9234:
9233:
9230:
9229:
9226:
9225:
9222:
9221:
9218:
9217:
9214:
9213:
9210:
9209:
9206:
9205:
9203:
9202:
9194:
9192:
9189:Goujianvirales
9181:
9173:
9172:
9169:
9168:
9166:
9165:
9158:
9151:
9144:
9137:
9130:
9123:
9116:
9109:
9102:
9095:
9087:
9085:
9077:
9076:
9074:
9073:
9066:
9059:
9052:
9045:
9037:
9035:
9032:Jingchuvirales
9024:
9021:Monjiviricetes
9016:
9015:
9012:
9011:
9009:
9008:
9000:
8998:
8987:
8984:Milneviricetes
8979:
8978:
8975:
8974:
8972:
8971:
8964:
8956:
8954:
8943:
8935:
8934:
8931:
8930:
8928:
8927:
8920:
8913:
8906:
8899:
8892:
8885:
8878:
8875:Leishbuviridae
8871:
8864:
8857:
8850:
8842:
8840:
8829:
8826:Ellioviricetes
8821:
8820:
8817:
8816:
8814:
8813:
8805:
8803:
8792:
8781:
8770:
8759:
8747:
8746:
8733:
8732:
8729:
8728:
8725:
8724:
8721:
8720:
8717:
8716:
8714:
8713:
8710:Sarthroviridae
8706:
8694:
8692:
8688:
8687:
8684:
8683:
8680:
8679:
8677:
8676:
8668:
8666:
8658:
8657:
8655:
8654:
8646:
8644:
8633:
8625:
8624:
8621:
8620:
8618:
8617:
8610:
8603:
8600:Alvernaviridae
8595:
8593:
8585:
8584:
8582:
8581:
8574:
8567:
8560:
8553:
8546:
8543:Solinviviridae
8539:
8532:
8529:Picornaviridae
8524:
8522:
8519:Picornavirales
8514:
8513:
8511:
8510:
8503:
8496:
8489:
8486:Nanhypoviridae
8482:
8475:
8468:
8461:
8458:Medioniviridae
8454:
8447:
8440:
8433:
8430:Cremegaviridae
8426:
8419:
8411:
8409:
8398:
8387:
8379:
8378:
8375:
8374:
8371:
8370:
8368:
8367:
8359:
8357:
8346:
8338:
8337:
8334:
8333:
8331:
8330:
8322:
8320:
8309:
8301:
8300:
8297:
8296:
8294:
8293:
8285:
8283:
8280:Wolframvirales
8272:
8264:
8263:
8260:
8259:
8257:
8256:
8249:
8241:
8239:
8231:
8230:
8228:
8227:
8220:
8213:
8206:
8198:
8196:
8185:
8174:
8166:
8165:
8162:
8161:
8158:
8157:
8155:
8154:
8147:
8140:
8132:
8130:
8119:
8111:
8110:
8107:
8106:
8104:
8103:
8100:Sinhaliviridae
8096:
8088:
8086:
8075:
8072:Magsaviricetes
8067:
8066:
8063:
8062:
8060:
8059:
8051:
8049:
8038:
8035:Flasuviricetes
8030:
8029:
8026:
8025:
8023:
8022:
8015:
8008:
8001:
7994:
7986:
7984:
7976:
7975:
7973:
7972:
7965:
7958:
7951:
7944:
7941:Endornaviridae
7937:
7930:
7922:
7920:
7912:
7911:
7909:
7908:
7901:
7894:
7887:
7879:
7877:
7866:
7855:
7844:
7833:
7821:
7820:
7807:
7806:
7803:
7802:
7799:
7798:
7795:
7794:
7791:
7790:
7788:
7787:
7784:Botybirnavirus
7776:
7769:
7757:
7755:
7751:
7750:
7747:
7746:
7743:
7742:
7740:
7739:
7736:Partitiviridae
7732:
7725:
7718:
7715:Curvulaviridae
7711:
7703:
7701:
7690:
7679:
7671:
7670:
7667:
7666:
7663:
7662:
7660:
7659:
7651:
7649:
7638:
7630:
7629:
7626:
7625:
7623:
7622:
7614:
7612:
7601:
7593:
7592:
7589:
7588:
7586:
7585:
7578:
7571:
7564:
7556:
7554:
7543:
7532:
7521:
7510:
7498:
7497:
7481:
7475:
7474:
7471:
7470:
7467:
7466:
7463:
7462:
7460:
7459:
7452:
7445:
7433:
7431:
7427:
7426:
7423:
7422:
7419:
7418:
7415:
7414:
7411:
7410:
7408:
7407:
7399:
7397:
7386:
7375:
7364:
7356:
7355:
7352:
7351:
7348:
7347:
7344:
7343:
7341:
7340:
7333:
7325:
7323:
7320:Geplafuvirales
7312:
7304:
7303:
7300:
7299:
7297:
7296:
7293:Redondoviridae
7288:
7286:
7278:
7277:
7275:
7274:
7267:
7259:
7257:
7249:
7248:
7246:
7245:
7237:
7235:
7227:
7226:
7224:
7223:
7215:
7213:
7205:
7204:
7202:
7201:
7193:
7191:
7180:
7169:
7161:
7160:
7157:
7156:
7153:
7152:
7150:
7149:
7141:
7139:
7128:
7120:
7119:
7116:
7115:
7113:
7112:
7104:
7102:
7091:
7080:
7069:
7061:
7060:
7057:
7056:
7053:
7052:
7049:
7048:
7046:
7045:
7037:
7035:
7024:
7013:
7002:
6994:
6993:
6990:
6989:
6986:
6985:
6982:
6981:
6979:
6978:
6975:Plectroviridae
6971:
6968:Paulinoviridae
6964:
6956:
6954:
6943:
6940:Faserviricetes
6932:
6929:Hofneiviricota
6921:
6910:
6898:
6897:
6884:
6883:
6880:
6879:
6876:
6875:
6872:
6871:
6869:
6868:
6861:
6850:
6843:
6836:
6833:Polydnaviridae
6829:
6822:
6815:
6808:
6801:
6798:Globuloviridae
6794:
6791:Fuselloviridae
6787:
6780:
6777:Bicaudaviridae
6773:
6770:Ampullaviridae
6761:
6759:
6755:
6754:
6751:
6750:
6748:
6747:
6739:
6737:
6733:
6732:
6730:
6729:
6722:
6719:Hytrosaviridae
6715:
6707:
6705:
6694:
6691:Naldaviricetes
6683:
6679:
6678:
6675:
6674:
6671:
6670:
6667:
6666:
6663:
6662:
6660:
6659:
6652:
6645:
6637:
6635:
6624:
6621:Laserviricetes
6613:
6610:Dividoviricota
6602:
6594:
6593:
6590:
6589:
6586:
6585:
6582:
6581:
6579:
6578:
6575:Corticoviridae
6570:
6568:
6560:
6559:
6557:
6556:
6548:
6546:
6538:
6537:
6535:
6534:
6526:
6524:
6516:
6515:
6513:
6512:
6504:
6502:
6491:
6483:
6482:
6479:
6478:
6476:
6475:
6467:
6465:
6454:
6446:
6445:
6442:
6441:
6439:
6438:
6430:
6428:
6417:
6406:
6398:
6397:
6394:
6393:
6390:
6389:
6387:
6386:
6379:
6372:
6364:
6362:
6359:Pimascovirales
6354:
6353:
6351:
6350:
6342:
6340:
6332:
6331:
6329:
6328:
6320:
6318:
6307:
6299:
6298:
6295:
6294:
6292:
6291:
6283:
6281:
6273:
6272:
6270:
6269:
6261:
6259:
6248:
6237:
6226:
6215:
6207:
6206:
6203:
6202:
6199:
6198:
6195:
6194:
6191:
6190:
6188:
6187:
6179:
6177:
6169:
6168:
6166:
6165:
6162:Polyomaviridae
6157:
6155:
6144:
6133:
6122:
6111:
6103:
6102:
6099:
6098:
6095:
6094:
6091:
6090:
6087:
6086:
6084:
6083:
6076:
6069:
6062:
6059:Salasmaviridae
6055:
6048:
6041:
6034:
6031:Herelleviridae
6027:
6020:
6017:Drexlerviridae
6013:
6010:Demerecviridae
6006:
5999:
5992:
5984:
5982:
5971:
5968:Caudoviricetes
5960:
5952:
5951:
5948:
5947:
5944:
5943:
5941:
5940:
5933:
5926:
5918:
5916:
5905:
5902:Herviviricetes
5894:
5883:
5880:Heunggongvirae
5872:
5864:
5863:
5860:
5859:
5856:
5855:
5852:
5851:
5848:
5847:
5845:
5844:
5836:
5834:
5826:
5825:
5823:
5822:
5815:
5807:
5805:
5802:Ligamenvirales
5794:
5783:
5772:
5761:
5749:
5748:
5732:
5726:
5725:
5713:
5712:
5705:
5698:
5690:
5684:
5683:
5676:
5674:: Polyomavirus
5668:
5658:
5657:External links
5655:
5653:
5652:
5603:
5554:
5505:
5468:PLOS Pathogens
5454:
5405:
5386:(6): 1223–43.
5370:
5327:
5321:978-1598746815
5320:
5302:
5253:
5216:PLOS Pathogens
5202:
5153:
5124:(9): 1378–85.
5104:
5055:
5014:
4978:
4963:
4933:
4895:
4846:
4797:
4776:10.1038/nrc947
4770:(12): 957–64.
4754:
4716:
4678:
4664:10.1086/597126
4637:
4596:
4561:
4512:
4461:
4432:(2): 295–303.
4412:
4373:(11): e49449.
4345:
4296:
4247:
4198:
4169:(10): 1560–5.
4149:
4097:
4048:
4013:
3978:
3949:(10): 1595–9.
3925:
3866:
3837:(9): 4586–90.
3817:
3766:
3729:PLOS Pathogens
3715:
3665:
3639:
3588:
3537:
3493:
3442:
3407:
3380:(3): 532–542.
3363:
3338:
3309:(9): 1627–34.
3289:
3260:(12): 5663–9.
3240:
3217:
3203:
3154:
3103:
3049:
3000:
2971:(9): 3623–34.
2951:
2902:
2843:
2802:
2758:
2719:(8): 3679–84.
2699:
2640:
2597:
2546:
2497:
2482:
2445:
2416:(1): a013250.
2393:
2356:PLOS Pathogens
2342:
2305:PLOS Pathogens
2288:
2247:
2210:PLOS Pathogens
2193:
2166:(6): 895–904.
2150:
2117:
2055:
2001:
1949:
1905:
1868:PLOS Pathogens
1851:
1802:
1734:
1703:(6): 1739–50.
1674:
1648:
1621:
1571:
1569:
1566:
1558:black sea bass
1522:
1519:
1509:
1506:
1476:
1473:
1440:Main article:
1437:
1434:
1396:
1393:
1380:
1379:
1377:
1374:
1371:
1366:
1363:
1360:
1357:
1351:
1350:
1348:
1345:
1342:
1337:
1334:
1329:
1326:
1318:
1317:
1315:
1312:
1309:
1304:
1301:
1296:
1293:
1285:
1284:
1282:
1279:
1276:
1271:
1268:
1263:
1260:
1252:
1251:
1249:
1246:
1243:
1238:
1235:
1230:
1227:
1219:
1218:
1216:
1213:
1210:
1205:
1202:
1197:
1194:
1186:
1185:
1183:
1180:
1177:
1172:
1169:
1164:
1161:
1153:
1152:
1150:
1145:
1142:
1137:
1134:
1129:
1126:
1118:
1117:
1115:
1105:
1102:
1097:
1094:
1089:
1086:
1078:
1077:
1075:
1072:
1069:
1064:
1061:
1056:
1053:
1045:
1044:
1042:
1039:
1036:
1031:
1028:
1023:
1020:
1012:
1011:
1009:
1006:
1003:
998:
995:
990:
987:
979:
978:
976:
971:
968:
963:
960:
955:
952:
944:
943:
941:
936:
933:
928:
925:
920:
917:
909:
908:
905:
902:
899:
893:
890:
887:
886:Proposed genus
884:
870:
867:
850:
847:
842:
841:
834:
827:
820:
813:
802:
801:
794:
787:
780:
773:
766:
750:
749:
744:(type species
738:
733:(type species
727:
722:(type species
700:Papillomavirus
680:
677:
656:
653:
625:
622:
566:retinoblastoma
556:
555:Tumor antigens
553:
551:
550:Viral proteins
548:
444:5HT2A receptor
402:hydrogen bonds
386:
383:
247:
244:
214:whose natural
207:Polyomaviridae
201:
200:
199:
198:
191:
184:
177:
170:
163:
153:
152:
148:
147:
144:Polyomaviridae
140:
136:
135:
128:
124:
123:
116:
112:
111:
104:
100:
99:
92:
88:
87:
80:
73:
72:
67:
63:
62:
49:
48:
37:
36:
28:
27:
25:Polyomaviridae
15:
9:
6:
4:
3:
2:
9692:
9681:
9678:
9676:
9673:
9671:
9668:
9667:
9665:
9648:
9643:
9639:
9635:
9630:
9626:
9622:
9617:
9613:
9609:
9604:
9600:
9596:
9591:
9587:
9583:
9578:
9574:
9570:
9565:
9561:
9556:
9550:
9546:
9541:
9535:
9531:
9530:
9528:
9526:
9522:
9518:
9513:
9473:
9472:
9468:
9467:
9465:
9463:
9462:
9457:
9451:
9450:
9446:
9445:
9443:
9441:
9440:
9439:Blubervirales
9435:
9432:
9430:
9429:
9424:
9421:
9419:
9418:
9413:
9410:
9408:
9407:
9402:
9399:
9397:
9396:
9391:
9387:
9383:
9377:
9373:
9343:
9342:
9338:
9336:
9335:
9334:Pseudoviridae
9331:
9329:
9328:
9324:
9322:
9321:
9320:Belpaoviridae
9317:
9316:
9314:
9312:
9311:
9306:
9303:
9301:
9300:
9295:
9292:
9290:
9289:
9284:
9281:
9279:
9278:
9273:
9270:
9268:
9267:
9262:
9258:
9254:
9248:
9244:
9241:
9239:
9235:
9201:
9200:
9196:
9195:
9193:
9191:
9190:
9185:
9182:
9180:
9179:
9174:
9164:
9163:
9159:
9157:
9156:
9152:
9150:
9149:
9148:Rhabdoviridae
9145:
9143:
9142:
9141:Pneumoviridae
9138:
9136:
9135:
9131:
9129:
9128:
9124:
9122:
9121:
9120:Mymonaviridae
9117:
9115:
9114:
9110:
9108:
9107:
9103:
9101:
9100:
9096:
9094:
9093:
9089:
9088:
9086:
9084:
9083:
9078:
9072:
9071:
9070:Natareviridae
9067:
9065:
9064:
9060:
9058:
9057:
9053:
9051:
9050:
9046:
9044:
9043:
9039:
9038:
9036:
9034:
9033:
9028:
9025:
9023:
9022:
9017:
9007:
9006:
9002:
9001:
8999:
8997:
8996:
8991:
8988:
8986:
8985:
8980:
8970:
8969:
8965:
8963:
8962:
8961:Amnoonviridae
8958:
8957:
8955:
8953:
8952:
8947:
8944:
8942:
8941:
8936:
8926:
8925:
8924:Wupedeviridae
8921:
8919:
8918:
8914:
8912:
8911:
8910:Phenuiviridae
8907:
8905:
8904:
8903:Phasmaviridae
8900:
8898:
8897:
8893:
8891:
8890:
8886:
8884:
8883:
8879:
8877:
8876:
8872:
8870:
8869:
8865:
8863:
8862:
8858:
8856:
8855:
8851:
8849:
8848:
8844:
8843:
8841:
8839:
8838:
8833:
8830:
8828:
8827:
8822:
8812:
8811:
8807:
8806:
8804:
8802:
8801:
8796:
8793:
8791:
8790:
8785:
8782:
8780:
8779:
8774:
8771:
8769:
8768:
8767:Orthornavirae
8763:
8760:
8758:
8757:
8752:
8748:
8744:
8738:
8734:
8712:
8711:
8707:
8705:
8704:
8699:
8696:
8695:
8693:
8689:
8675:
8674:
8670:
8669:
8667:
8665:
8664:
8663:Stellavirales
8659:
8653:
8652:
8648:
8647:
8645:
8643:
8642:
8641:Patatavirales
8637:
8634:
8632:
8631:
8626:
8616:
8615:
8614:Solemoviridae
8611:
8609:
8608:
8604:
8602:
8601:
8597:
8596:
8594:
8592:
8591:
8590:Sobelivirales
8586:
8580:
8579:
8575:
8573:
8572:
8568:
8566:
8565:
8561:
8559:
8558:
8554:
8552:
8551:
8550:Caliciviridae
8547:
8545:
8544:
8540:
8538:
8537:
8533:
8531:
8530:
8526:
8525:
8523:
8521:
8520:
8515:
8509:
8508:
8507:Tobaniviridae
8504:
8502:
8501:
8497:
8495:
8494:
8490:
8488:
8487:
8483:
8481:
8480:
8476:
8474:
8473:
8472:Mononiviridae
8469:
8467:
8466:
8465:Mesoniviridae
8462:
8460:
8459:
8455:
8453:
8452:
8451:Gresnaviridae
8448:
8446:
8445:
8444:Euroniviridae
8441:
8439:
8438:
8437:Coronaviridae
8434:
8432:
8431:
8427:
8425:
8424:
8423:Arteriviridae
8420:
8418:
8417:
8416:Abyssoviridae
8413:
8412:
8410:
8408:
8407:
8402:
8399:
8397:
8396:
8391:
8388:
8386:
8385:
8380:
8366:
8365:
8361:
8360:
8358:
8356:
8355:
8350:
8347:
8345:
8344:
8339:
8329:
8328:
8324:
8323:
8321:
8319:
8318:
8317:Cryppavirales
8313:
8310:
8308:
8307:
8302:
8292:
8291:
8287:
8286:
8284:
8282:
8281:
8276:
8273:
8271:
8270:
8265:
8255:
8254:
8253:Steitzviridae
8250:
8248:
8247:
8243:
8242:
8240:
8238:
8237:
8232:
8226:
8225:
8224:Solspiviridae
8221:
8219:
8218:
8214:
8212:
8211:
8207:
8205:
8204:
8203:Atkinsviridae
8200:
8199:
8197:
8195:
8194:
8189:
8186:
8184:
8183:
8182:Leviviricetes
8178:
8175:
8173:
8172:
8171:Lenarviricota
8167:
8153:
8152:
8151:Tombusviridae
8148:
8146:
8145:
8141:
8139:
8138:
8134:
8133:
8131:
8129:
8128:
8123:
8120:
8118:
8117:
8112:
8102:
8101:
8097:
8095:
8094:
8090:
8089:
8087:
8085:
8084:
8083:Nodamuvirales
8079:
8076:
8074:
8073:
8068:
8058:
8057:
8053:
8052:
8050:
8048:
8047:
8042:
8039:
8037:
8036:
8031:
8021:
8020:
8016:
8014:
8013:
8009:
8007:
8006:
8002:
8000:
7999:
7995:
7993:
7992:
7988:
7987:
7985:
7983:
7982:
7977:
7971:
7970:
7966:
7964:
7963:
7959:
7957:
7956:
7952:
7950:
7949:
7945:
7943:
7942:
7938:
7936:
7935:
7931:
7929:
7928:
7924:
7923:
7921:
7919:
7918:
7913:
7907:
7906:
7905:Matonaviridae
7902:
7900:
7899:
7895:
7893:
7892:
7888:
7886:
7885:
7881:
7880:
7878:
7876:
7875:
7874:Hepelivirales
7870:
7867:
7865:
7864:
7863:Alsuviricetes
7859:
7856:
7854:
7853:
7848:
7845:
7843:
7842:
7841:Orthornavirae
7837:
7834:
7832:
7831:
7826:
7822:
7818:
7812:
7808:
7786:
7785:
7780:
7777:
7775:
7774:
7770:
7768:
7767:
7762:
7759:
7758:
7756:
7752:
7738:
7737:
7733:
7731:
7730:
7726:
7724:
7723:
7719:
7717:
7716:
7712:
7710:
7709:
7708:Amalgaviridae
7705:
7704:
7702:
7700:
7699:
7694:
7691:
7689:
7688:
7683:
7680:
7678:
7677:
7672:
7658:
7657:
7653:
7652:
7650:
7648:
7647:
7642:
7639:
7637:
7636:
7631:
7621:
7620:
7616:
7615:
7613:
7611:
7610:
7605:
7602:
7600:
7599:
7594:
7584:
7583:
7579:
7577:
7576:
7575:Quadriviridae
7572:
7570:
7569:
7565:
7563:
7562:
7561:Chrysoviridae
7558:
7557:
7555:
7553:
7552:
7551:Ghabrivirales
7547:
7544:
7542:
7541:
7536:
7533:
7531:
7530:
7525:
7522:
7520:
7519:
7518:Orthornavirae
7514:
7511:
7509:
7508:
7503:
7499:
7495:
7494:dsRNA viruses
7489:
7485:
7482:
7480:
7476:
7458:
7457:
7453:
7451:
7450:
7446:
7444:
7443:
7442:Anelloviridae
7438:
7435:
7434:
7432:
7428:
7406:
7405:
7401:
7400:
7398:
7396:
7395:
7394:Haloruvirales
7390:
7387:
7385:
7384:
7379:
7376:
7374:
7373:
7368:
7365:
7363:
7362:
7357:
7339:
7338:
7337:Genomoviridae
7334:
7332:
7331:
7330:Geminiviridae
7327:
7326:
7324:
7322:
7321:
7316:
7313:
7311:
7310:
7305:
7295:
7294:
7290:
7289:
7287:
7285:
7284:
7279:
7273:
7272:
7268:
7266:
7265:
7264:Metaxyviridae
7261:
7260:
7258:
7256:
7255:
7250:
7244:
7243:
7239:
7238:
7236:
7234:
7233:
7228:
7222:
7221:
7217:
7216:
7214:
7212:
7211:
7206:
7200:
7199:
7195:
7194:
7192:
7190:
7189:
7184:
7181:
7179:
7178:
7177:Arfiviricetes
7173:
7170:
7168:
7167:
7162:
7148:
7147:
7143:
7142:
7140:
7138:
7137:
7132:
7129:
7127:
7126:
7121:
7111:
7110:
7106:
7105:
7103:
7101:
7100:
7095:
7092:
7090:
7089:
7084:
7081:
7079:
7078:
7077:Cossaviricota
7073:
7070:
7068:
7067:
7062:
7044:
7043:
7039:
7038:
7036:
7034:
7033:
7028:
7025:
7023:
7022:
7017:
7014:
7012:
7011:
7006:
7003:
7001:
7000:
6995:
6977:
6976:
6972:
6970:
6969:
6965:
6963:
6962:
6958:
6957:
6955:
6953:
6952:
6951:Tubulavirales
6947:
6944:
6942:
6941:
6936:
6933:
6931:
6930:
6925:
6922:
6920:
6919:
6914:
6911:
6909:
6908:
6903:
6899:
6895:
6894:ssDNA viruses
6889:
6885:
6867:
6866:
6865:Rhizidiovirus
6862:
6860:
6859:
6854:
6851:
6849:
6848:
6847:Thaspiviridae
6844:
6842:
6841:
6837:
6835:
6834:
6830:
6828:
6827:
6826:Plasmaviridae
6823:
6821:
6820:
6816:
6814:
6813:
6812:Halspiviridae
6809:
6807:
6806:
6802:
6800:
6799:
6795:
6793:
6792:
6788:
6786:
6785:
6781:
6779:
6778:
6774:
6772:
6771:
6766:
6763:
6762:
6760:
6756:
6746:
6745:
6741:
6740:
6738:
6734:
6728:
6727:
6723:
6721:
6720:
6716:
6714:
6713:
6712:Baculoviridae
6709:
6708:
6706:
6704:
6703:
6698:
6695:
6693:
6692:
6687:
6684:
6680:
6658:
6657:
6653:
6651:
6650:
6649:Simuloviridae
6646:
6644:
6643:
6639:
6638:
6636:
6634:
6633:
6628:
6625:
6623:
6622:
6617:
6614:
6612:
6611:
6606:
6603:
6601:
6600:
6599:Helvetiavirae
6595:
6577:
6576:
6572:
6571:
6569:
6567:
6566:
6561:
6555:
6554:
6550:
6549:
6547:
6545:
6544:
6539:
6533:
6532:
6528:
6527:
6525:
6523:
6522:
6521:Kalamavirales
6517:
6511:
6510:
6506:
6505:
6503:
6501:
6500:
6499:Belfryvirales
6495:
6492:
6490:
6489:
6484:
6474:
6473:
6472:Adintoviridae
6469:
6468:
6466:
6464:
6463:
6458:
6455:
6453:
6452:
6447:
6437:
6436:
6435:Lavidaviridae
6432:
6431:
6429:
6427:
6426:
6421:
6418:
6416:
6415:
6410:
6407:
6405:
6404:
6399:
6385:
6384:
6380:
6378:
6377:
6373:
6371:
6370:
6366:
6365:
6363:
6361:
6360:
6355:
6349:
6348:
6344:
6343:
6341:
6339:
6338:
6337:Imitervirales
6333:
6327:
6326:
6322:
6321:
6319:
6317:
6316:
6311:
6308:
6306:
6305:
6304:Megaviricetes
6300:
6290:
6289:
6285:
6284:
6282:
6280:
6279:
6274:
6268:
6267:
6263:
6262:
6260:
6258:
6257:
6252:
6249:
6247:
6246:
6241:
6238:
6236:
6235:
6230:
6227:
6225:
6224:
6219:
6216:
6214:
6213:
6208:
6186:
6185:
6181:
6180:
6178:
6176:
6175:
6170:
6164:
6163:
6159:
6158:
6156:
6154:
6153:
6152:Sepolyvirales
6148:
6145:
6143:
6142:
6137:
6134:
6132:
6131:
6130:Cossaviricota
6126:
6123:
6121:
6120:
6115:
6112:
6110:
6109:
6104:
6082:
6081:
6080:Zobellviridae
6077:
6075:
6074:
6070:
6068:
6067:
6066:Schitoviridae
6063:
6061:
6060:
6056:
6054:
6053:
6049:
6047:
6046:
6042:
6040:
6039:
6035:
6033:
6032:
6028:
6026:
6025:
6024:Guelinviridae
6021:
6019:
6018:
6014:
6012:
6011:
6007:
6005:
6004:
6000:
5998:
5997:
5993:
5991:
5990:
5986:
5985:
5983:
5981:
5980:
5975:
5972:
5970:
5969:
5964:
5961:
5959:
5958:
5953:
5939:
5938:
5934:
5932:
5931:
5930:Herpesviridae
5927:
5925:
5924:
5920:
5919:
5917:
5915:
5914:
5913:Herpesvirales
5909:
5906:
5904:
5903:
5898:
5895:
5893:
5892:
5891:Peploviricota
5887:
5884:
5882:
5881:
5876:
5873:
5871:
5870:
5869:Duplodnaviria
5865:
5843:
5842:
5838:
5837:
5835:
5833:
5832:
5827:
5821:
5820:
5816:
5814:
5813:
5809:
5808:
5806:
5804:
5803:
5798:
5795:
5793:
5792:
5791:Tokiviricetes
5787:
5784:
5782:
5781:
5780:Taleaviricota
5776:
5773:
5771:
5770:
5765:
5762:
5760:
5759:
5754:
5750:
5746:
5745:dsDNA viruses
5740:
5736:
5733:
5731:
5727:
5722:
5718:
5711:
5706:
5704:
5699:
5697:
5692:
5691:
5688:
5682:
5681:
5677:
5675:
5673:
5669:
5667:
5665:
5661:
5660:
5648:
5644:
5639:
5634:
5630:
5626:
5622:
5618:
5614:
5607:
5599:
5595:
5590:
5585:
5581:
5577:
5573:
5569:
5565:
5558:
5550:
5546:
5541:
5536:
5532:
5528:
5524:
5520:
5516:
5509:
5501:
5497:
5492:
5487:
5482:
5477:
5473:
5469:
5465:
5458:
5450:
5446:
5441:
5436:
5432:
5428:
5424:
5420:
5416:
5409:
5401:
5397:
5393:
5389:
5385:
5381:
5374:
5366:
5362:
5358:
5354:
5350:
5346:
5343:(2): 414–21.
5342:
5338:
5331:
5323:
5317:
5314:. Routledge.
5313:
5306:
5298:
5294:
5289:
5284:
5280:
5276:
5272:
5268:
5264:
5257:
5249:
5245:
5240:
5235:
5230:
5225:
5221:
5217:
5213:
5206:
5198:
5194:
5189:
5184:
5180:
5176:
5173:(6): 1250–6.
5172:
5168:
5164:
5157:
5149:
5145:
5140:
5135:
5131:
5127:
5123:
5119:
5115:
5108:
5100:
5096:
5092:
5088:
5083:
5078:
5074:
5070:
5066:
5059:
5051:
5047:
5042:
5037:
5034:(5): 1080–9.
5033:
5029:
5025:
5018:
5010:
5006:
5002:
4998:
4994:
4990:
4982:
4974:
4970:
4966:
4960:
4956:
4952:
4948:
4944:
4937:
4929:
4925:
4921:
4917:
4913:
4909:
4902:
4900:
4891:
4887:
4883:
4879:
4874:
4869:
4866:(2): 215–23.
4865:
4861:
4857:
4850:
4842:
4838:
4833:
4828:
4824:
4820:
4817:(9): 1295–7.
4816:
4812:
4808:
4801:
4793:
4789:
4785:
4781:
4777:
4773:
4769:
4765:
4758:
4750:
4746:
4742:
4738:
4734:
4730:
4723:
4721:
4712:
4708:
4704:
4700:
4696:
4692:
4685:
4683:
4674:
4670:
4665:
4660:
4657:(6): 837–46.
4656:
4652:
4648:
4641:
4633:
4629:
4624:
4619:
4616:(6): 354–77.
4615:
4611:
4607:
4600:
4592:
4588:
4584:
4580:
4576:
4572:
4565:
4557:
4553:
4548:
4543:
4539:
4535:
4531:
4527:
4523:
4516:
4508:
4504:
4499:
4494:
4489:
4484:
4480:
4476:
4472:
4465:
4457:
4453:
4448:
4443:
4439:
4435:
4431:
4427:
4423:
4416:
4408:
4404:
4399:
4394:
4389:
4384:
4380:
4376:
4372:
4368:
4364:
4360:
4356:
4349:
4341:
4337:
4332:
4327:
4323:
4319:
4316:(19): 10887.
4315:
4311:
4307:
4300:
4292:
4288:
4283:
4278:
4274:
4270:
4266:
4262:
4258:
4251:
4243:
4239:
4234:
4229:
4225:
4221:
4217:
4213:
4209:
4202:
4194:
4190:
4185:
4180:
4176:
4172:
4168:
4164:
4160:
4153:
4145:
4141:
4136:
4131:
4127:
4123:
4119:
4115:
4111:
4104:
4102:
4093:
4089:
4084:
4079:
4075:
4071:
4068:(8): 4130–6.
4067:
4063:
4059:
4052:
4044:
4040:
4036:
4032:
4028:
4024:
4017:
4009:
4005:
4001:
3997:
3993:
3989:
3982:
3974:
3970:
3965:
3960:
3956:
3952:
3948:
3944:
3940:
3936:
3929:
3921:
3917:
3912:
3907:
3902:
3897:
3893:
3889:
3886:(3): e58021.
3885:
3881:
3877:
3870:
3862:
3858:
3853:
3848:
3844:
3840:
3836:
3832:
3828:
3821:
3813:
3809:
3805:
3801:
3796:
3791:
3788:(8): 770–82.
3787:
3783:
3782:
3777:
3770:
3762:
3758:
3753:
3748:
3743:
3738:
3734:
3730:
3726:
3719:
3711:
3707:
3702:
3697:
3693:
3689:
3686:(6): 1243–9.
3685:
3681:
3677:
3669:
3654:
3650:
3643:
3635:
3631:
3626:
3621:
3616:
3611:
3607:
3603:
3599:
3592:
3584:
3580:
3575:
3570:
3565:
3560:
3556:
3552:
3548:
3541:
3533:
3529:
3525:
3521:
3517:
3513:
3509:
3505:
3497:
3489:
3485:
3480:
3475:
3470:
3465:
3461:
3457:
3453:
3446:
3438:
3434:
3430:
3426:
3422:
3418:
3411:
3403:
3399:
3395:
3391:
3387:
3383:
3379:
3375:
3367:
3351:
3345:
3343:
3334:
3330:
3325:
3320:
3316:
3312:
3308:
3304:
3300:
3293:
3285:
3281:
3276:
3271:
3267:
3263:
3259:
3255:
3251:
3244:
3236:
3232:
3228:
3221:
3213:
3207:
3199:
3195:
3190:
3185:
3181:
3177:
3173:
3169:
3165:
3158:
3150:
3146:
3141:
3136:
3131:
3126:
3122:
3118:
3114:
3107:
3099:
3095:
3090:
3085:
3081:
3077:
3074:(6): 509–15.
3073:
3069:
3065:
3058:
3056:
3054:
3045:
3041:
3036:
3031:
3027:
3023:
3019:
3015:
3011:
3004:
2996:
2992:
2987:
2982:
2978:
2974:
2970:
2966:
2962:
2955:
2947:
2943:
2938:
2933:
2929:
2925:
2922:(2): 125–35.
2921:
2917:
2913:
2906:
2898:
2894:
2889:
2884:
2879:
2874:
2870:
2866:
2862:
2858:
2854:
2847:
2839:
2835:
2830:
2825:
2822:(5): 887–97.
2821:
2817:
2813:
2806:
2798:
2794:
2790:
2786:
2782:
2778:
2775:(1): 167–76.
2774:
2770:
2762:
2754:
2750:
2745:
2740:
2735:
2730:
2726:
2722:
2718:
2714:
2710:
2703:
2695:
2691:
2686:
2681:
2676:
2671:
2667:
2663:
2659:
2655:
2651:
2644:
2636:
2632:
2628:
2624:
2620:
2616:
2612:
2608:
2601:
2593:
2589:
2584:
2583:11392/2378829
2579:
2574:
2569:
2565:
2561:
2557:
2550:
2542:
2538:
2533:
2528:
2524:
2520:
2516:
2512:
2508:
2501:
2493:
2489:
2485:
2483:9780123747716
2479:
2475:
2471:
2467:
2463:
2456:
2454:
2452:
2450:
2441:
2437:
2432:
2427:
2423:
2419:
2415:
2411:
2407:
2400:
2398:
2389:
2385:
2380:
2375:
2370:
2365:
2361:
2357:
2353:
2346:
2338:
2334:
2329:
2324:
2319:
2314:
2310:
2306:
2302:
2295:
2293:
2284:
2280:
2273:
2266:
2264:
2262:
2260:
2258:
2256:
2254:
2252:
2243:
2239:
2234:
2229:
2224:
2219:
2215:
2211:
2207:
2200:
2198:
2189:
2185:
2181:
2177:
2173:
2169:
2165:
2161:
2154:
2138:
2132:
2130:
2128:
2126:
2124:
2122:
2113:
2109:
2104:
2099:
2095:
2091:
2087:
2083:
2079:
2075:
2071:
2064:
2062:
2060:
2051:
2047:
2042:
2037:
2032:
2027:
2023:
2019:
2018:F1000Research
2015:
2008:
2006:
1997:
1993:
1988:
1983:
1979:
1975:
1971:
1967:
1963:
1956:
1954:
1945:
1941:
1936:
1931:
1928:(8): 647–54.
1927:
1923:
1919:
1912:
1910:
1901:
1897:
1892:
1887:
1882:
1877:
1873:
1869:
1865:
1858:
1856:
1847:
1843:
1838:
1833:
1829:
1825:
1821:
1817:
1813:
1806:
1798:
1794:
1789:
1784:
1780:
1776:
1773:(4): 264–76.
1772:
1768:
1764:
1757:
1755:
1753:
1751:
1749:
1747:
1745:
1743:
1741:
1739:
1730:
1726:
1721:
1716:
1711:
1706:
1702:
1698:
1694:
1687:
1685:
1683:
1681:
1679:
1663:
1659:
1652:
1644:
1638:
1636:
1634:
1632:
1630:
1628:
1626:
1617:
1613:
1608:
1603:
1599:
1595:
1591:
1587:
1583:
1576:
1572:
1565:
1563:
1559:
1554:
1551:
1547:
1543:
1542:Sarah Stewart
1539:
1538:parotid gland
1535:
1531:
1527:
1518:
1516:
1505:
1501:
1497:
1495:
1489:
1487:
1481:
1472:
1470:
1466:
1465:mesotheliomas
1462:
1458:
1454:
1453:polio vaccine
1449:
1443:
1433:
1431:
1427:
1423:
1419:
1415:
1411:
1407:
1403:
1392:
1389:
1386:
1378:
1375:
1372:
1370:
1367:
1364:
1361:
1358:
1356:
1353:
1352:
1349:
1346:
1343:
1341:
1338:
1335:
1333:
1330:
1327:
1324:
1320:
1319:
1316:
1313:
1310:
1308:
1305:
1302:
1300:
1297:
1294:
1291:
1287:
1286:
1283:
1280:
1277:
1275:
1272:
1269:
1267:
1264:
1261:
1258:
1254:
1253:
1250:
1247:
1244:
1242:
1239:
1236:
1234:
1231:
1228:
1225:
1221:
1220:
1217:
1214:
1211:
1209:
1206:
1203:
1201:
1198:
1195:
1192:
1188:
1187:
1184:
1181:
1178:
1176:
1173:
1170:
1168:
1165:
1162:
1159:
1155:
1154:
1151:
1149:
1146:
1143:
1141:
1138:
1135:
1133:
1130:
1127:
1124:
1120:
1119:
1116:
1114:
1110:
1106:
1103:
1101:
1098:
1095:
1093:
1090:
1087:
1084:
1080:
1079:
1076:
1073:
1070:
1068:
1065:
1062:
1060:
1057:
1054:
1051:
1047:
1046:
1043:
1040:
1037:
1035:
1032:
1029:
1027:
1024:
1021:
1018:
1014:
1013:
1010:
1007:
1004:
1002:
999:
996:
994:
991:
988:
985:
981:
980:
977:
975:
972:
969:
967:
964:
961:
959:
956:
953:
950:
946:
945:
942:
940:
937:
934:
932:
929:
926:
924:
921:
918:
915:
911:
910:
906:
903:
900:
897:
894:
891:
888:
885:
881:
878:
876:
866:
863:
861:
857:
846:
840:
839:
835:
833:
832:
828:
826:
825:
821:
819:
818:
814:
812:
811:
807:
806:
805:
800:
799:
795:
793:
792:
788:
786:
785:
781:
779:
778:
774:
772:
771:
767:
765:
764:
760:
759:
758:
756:
747:
743:
739:
736:
732:
728:
725:
721:
717:
716:
715:
713:
709:
705:
701:
697:
696:Papovaviridae
693:
692:
691:Papovaviridae
687:
676:
674:
670:
666:
662:
652:
650:
646:
643:
639:
635:
631:
621:
619:
615:
612:
608:
604:
600:
595:
593:
590:
586:
582:
578:
574:
569:
567:
562:
547:
545:
541:
537:
533:
529:
525:
520:
516:
512:
508:
504:
500:
496:
495:messenger RNA
493:
489:
485:
481:
477:
471:
469:
465:
461:
457:
453:
449:
445:
441:
437:
433:
429:
425:
421:
412:
408:
403:
399:
395:
391:
382:
380:
376:
372:
368:
364:
360:
356:
352:
351:translational
348:
344:
340:
336:
332:
324:
319:
315:
313:
309:
305:
301:
297:
293:
289:
285:
281:
278:
277:non-enveloped
269:
265:
260:
257:
252:
243:
241:
237:
233:
229:
225:
221:
217:
213:
209:
208:
197:
196:
192:
190:
189:
185:
183:
182:
178:
176:
175:
171:
169:
168:
164:
162:
161:
157:
156:
154:
149:
146:
145:
141:
138:
137:
134:
133:
132:Sepolyvirales
129:
126:
125:
122:
121:
117:
114:
113:
110:
109:
108:Cossaviricota
105:
102:
101:
98:
97:
93:
90:
89:
86:
85:
81:
78:
75:
74:
71:
68:
65:
64:
59:
54:
50:
46:
42:
38:
34:
29:
26:
22:
19:
9524:
9469:
9461:Ortervirales
9459:
9447:
9437:
9426:
9415:
9406:Pararnavirae
9404:
9393:
9341:Retroviridae
9339:
9332:
9325:
9318:
9310:Ortervirales
9308:
9297:
9286:
9277:Pararnavirae
9275:
9264:
9197:
9187:
9176:
9162:Xinmoviridae
9160:
9153:
9146:
9139:
9132:
9127:Nyamiviridae
9125:
9118:
9113:Lispiviridae
9111:
9104:
9099:Bornaviridae
9097:
9090:
9080:
9068:
9063:Myriaviridae
9061:
9054:
9047:
9042:Aliusviridae
9040:
9030:
9019:
9003:
8993:
8982:
8966:
8959:
8949:
8938:
8922:
8917:Tospoviridae
8915:
8908:
8901:
8894:
8889:Nairoviridae
8887:
8880:
8873:
8868:Hantaviridae
8866:
8859:
8854:Arenaviridae
8852:
8847:Cruliviridae
8845:
8837:Bunyavirales
8835:
8824:
8808:
8798:
8787:
8776:
8765:
8754:
8708:
8701:
8697:
8673:Astroviridae
8671:
8661:
8649:
8639:
8628:
8612:
8607:Barnaviridae
8605:
8598:
8588:
8576:
8569:
8562:
8555:
8548:
8541:
8536:Marnaviridae
8534:
8527:
8517:
8505:
8498:
8493:Olifoviridae
8491:
8484:
8477:
8470:
8463:
8456:
8449:
8442:
8435:
8428:
8421:
8414:
8404:
8393:
8384:Pisuviricota
8382:
8362:
8354:Ourlivirales
8352:
8343:Miaviricetes
8341:
8325:
8315:
8304:
8290:Narnaviridae
8288:
8278:
8267:
8251:
8246:Blumeviridae
8244:
8236:Timlovirales
8234:
8222:
8217:Fiersviridae
8215:
8208:
8201:
8193:Norzivirales
8191:
8180:
8169:
8149:
8144:Luteoviridae
8142:
8135:
8125:
8114:
8098:
8091:
8081:
8070:
8056:Flaviviridae
8054:
8044:
8033:
8017:
8010:
8003:
7996:
7989:
7979:
7969:Virgaviridae
7967:
7960:
7953:
7946:
7939:
7932:
7927:Bromoviridae
7925:
7915:
7903:
7896:
7889:
7882:
7872:
7861:
7850:
7839:
7828:
7782:
7778:
7771:
7766:Birnaviridae
7764:
7760:
7734:
7727:
7720:
7713:
7706:
7698:Durnavirales
7696:
7685:
7676:Pisuviricota
7674:
7656:Cystoviridae
7654:
7646:Mindivirales
7644:
7633:
7617:
7607:
7596:
7580:
7573:
7566:
7559:
7549:
7538:
7527:
7516:
7505:
7456:Spiraviridae
7454:
7447:
7440:
7436:
7402:
7392:
7381:
7372:Saleviricota
7370:
7359:
7335:
7328:
7318:
7307:
7291:
7283:Recrevirales
7281:
7269:
7262:
7254:Mulpavirales
7252:
7242:Smacoviridae
7240:
7232:Cremevirales
7230:
7220:Circoviridae
7218:
7210:Cirlivirales
7208:
7196:
7188:Baphyvirales
7186:
7175:
7164:
7146:Parvoviridae
7144:
7136:Piccovirales
7134:
7123:
7109:Bidnaviridae
7107:
7097:
7088:Mouviricetes
7086:
7075:
7066:Shotokuvirae
7064:
7042:Microviridae
7040:
7032:Petitvirales
7030:
7019:
7010:Phixviricota
7008:
6997:
6973:
6966:
6959:
6949:
6938:
6927:
6916:
6907:Monodnaviria
6905:
6863:
6858:Dinodnavirus
6856:
6852:
6845:
6838:
6831:
6824:
6819:Ovaliviridae
6817:
6810:
6805:Guttaviridae
6803:
6796:
6789:
6784:Clavaviridae
6782:
6775:
6768:
6764:
6742:
6724:
6717:
6710:
6700:
6689:
6654:
6647:
6640:
6630:
6619:
6608:
6597:
6573:
6563:
6553:Adenoviridae
6551:
6541:
6531:Tectiviridae
6529:
6519:
6509:Turriviridae
6507:
6497:
6486:
6470:
6460:
6449:
6433:
6423:
6412:
6401:
6381:
6376:Iridoviridae
6374:
6367:
6357:
6345:
6335:
6323:
6313:
6302:
6286:
6278:Chitovirales
6276:
6266:Asfarviridae
6264:
6254:
6243:
6232:
6223:Bamfordvirae
6221:
6212:Varidnaviria
6210:
6182:
6172:
6161:
6160:
6150:
6139:
6128:
6119:Shotokuvirae
6117:
6108:Monodnaviria
6106:
6078:
6073:Siphoviridae
6071:
6064:
6057:
6050:
6043:
6036:
6029:
6022:
6015:
6008:
6003:Chaseviridae
6001:
5994:
5987:
5979:Caudovirales
5977:
5966:
5955:
5935:
5928:
5921:
5911:
5900:
5889:
5878:
5867:
5839:
5831:Primavirales
5829:
5817:
5810:
5800:
5789:
5778:
5767:
5756:
5679:
5671:
5663:
5620:
5616:
5606:
5571:
5567:
5557:
5522:
5518:
5508:
5471:
5467:
5457:
5422:
5418:
5408:
5383:
5379:
5373:
5340:
5336:
5330:
5311:
5305:
5270:
5266:
5256:
5219:
5215:
5205:
5170:
5166:
5156:
5121:
5117:
5107:
5075:(4): 485–8.
5072:
5068:
5058:
5031:
5027:
5017:
4995:(1): 23–36.
4992:
4988:
4981:
4946:
4936:
4911:
4907:
4863:
4859:
4849:
4814:
4810:
4800:
4767:
4763:
4757:
4732:
4728:
4694:
4690:
4654:
4650:
4640:
4613:
4609:
4599:
4577:(2): 63–72.
4574:
4570:
4564:
4529:
4525:
4515:
4478:
4474:
4464:
4429:
4425:
4415:
4370:
4366:
4355:Greninger AL
4348:
4313:
4309:
4299:
4264:
4260:
4250:
4215:
4211:
4201:
4166:
4162:
4152:
4117:
4113:
4065:
4061:
4051:
4026:
4022:
4016:
3991:
3987:
3981:
3946:
3942:
3928:
3883:
3879:
3869:
3834:
3830:
3820:
3785:
3779:
3769:
3732:
3728:
3718:
3683:
3679:
3668:
3656:. Retrieved
3652:
3642:
3605:
3601:
3591:
3554:
3550:
3540:
3507:
3503:
3496:
3459:
3455:
3445:
3420:
3416:
3410:
3377:
3373:
3366:
3354:. Retrieved
3306:
3302:
3292:
3257:
3253:
3243:
3234:
3230:
3220:
3206:
3171:
3167:
3157:
3120:
3116:
3106:
3071:
3067:
3017:
3013:
3003:
2968:
2964:
2954:
2919:
2915:
2905:
2860:
2856:
2846:
2819:
2815:
2805:
2772:
2768:
2761:
2716:
2712:
2702:
2657:
2653:
2643:
2613:(1): 69–85.
2610:
2606:
2600:
2563:
2559:
2549:
2514:
2510:
2500:
2465:
2461:
2413:
2409:
2359:
2355:
2345:
2308:
2304:
2282:
2278:
2213:
2209:
2163:
2159:
2153:
2141:. Retrieved
2137:"Viral Zone"
2077:
2073:
2021:
2017:
1972:(2): 310–8.
1969:
1965:
1925:
1921:
1871:
1867:
1819:
1815:
1805:
1770:
1766:
1700:
1696:
1665:. Retrieved
1661:
1651:
1589:
1585:
1575:
1555:
1546:Bernice Eddy
1530:Ludwik Gross
1524:
1511:
1502:
1498:
1494:renal biopsy
1490:
1482:
1478:
1457:brain tumors
1445:
1398:
1390:
1384:
1383:
1354:
1322:
1289:
1256:
1223:
1190:
1157:
1122:
1082:
1049:
1016:
983:
948:
913:
892:Abbreviation
872:
864:
852:
843:
836:
829:
822:
815:
808:
803:
796:
789:
782:
775:
768:
761:
754:
751:
741:
730:
719:
704:Polyomavirus
703:
699:
695:
694:. (The name
689:
682:
658:
645:viral capsid
627:
596:
570:
558:
472:
432:gangliosides
426:residues of
417:
341:as a single
328:
292:viral capsid
274:
206:
205:
204:
193:
186:
179:
172:
165:
158:
143:
142:
131:
130:
119:
107:
96:Shotokuvirae
95:
84:Monodnaviria
83:
76:
66:(unranked):
45:polyomavirus
44:
24:
18:
9549:Wikispecies
9327:Metaviridae
9106:Filoviridae
9092:Artoviridae
9005:Aspiviridae
8882:Mypoviridae
8861:Fimoviridae
8651:Potyviridae
8564:Secoviridae
8557:Iflaviridae
8500:Roniviridae
8406:Nidovirales
8327:Mitoviridae
8210:Duinviridae
8127:Tolivirales
8093:Nodaviridae
8019:Tymoviridae
7981:Tymovirales
7962:Togaviridae
7955:Mayoviridae
7948:Kitaviridae
7898:Hepeviridae
7891:Benyviridae
7722:Hypoviridae
7582:Totiviridae
7271:Nanoviridae
7099:Polivirales
6999:Sangervirae
6744:Nimaviridae
6726:Nudiviridae
6702:Lefavirales
6565:Vinavirales
6543:Rowavirales
6369:Ascoviridae
6347:Mimiviridae
6315:Algavirales
6256:Asfuvirales
6045:Podoviridae
5957:Uroviricota
5819:Rudiviridae
5769:Zilligvirae
5664:ICTV Report
4359:Parsonnet J
4212:JCI Insight
1822:(1): 61–9.
1720:10037/13151
1461:bone tumors
1428:(MCV) with
1410:nephropathy
1376:None known
1369:NC_034253.1
1109:nephropathy
907:References
661:agnoprotein
655:Agnoprotein
642:icosahedral
601:is used in
536:agnoprotein
460:endocytosed
430:, commonly
424:sialic acid
367:agnoprotein
300:icosahedral
224:nephropathy
9664:Categories
9199:Yueviridae
9155:Sunviridae
9049:Chuviridae
8810:Qinviridae
8691:Unassigned
7754:Unassigned
7619:Reoviridae
7609:Reovirales
7430:Unassigned
7361:Trapavirae
6961:Inoviridae
6758:Unassigned
6736:Unassigned
6682:Unassigned
6288:Poxviridae
6038:Myoviridae
4735:(5): 687.
3658:18 January
3462:(1): 207.
2285:: 121–131.
2216:(5): e64.
1922:Nephrology
1656:taxonomy.
1568:References
1347:None known
1314:None known
1215:None known
1182:None known
1074:None known
1041:None known
1008:None known
889:Virus name
499:cell cycle
371:non-coding
312:VP2 or VP3
304:capsomeres
296:nanometers
288:base pairs
43:showing a
41:Micrograph
9540:Q18670504
9395:Riboviria
9266:Riboviria
8800:Muvirales
8756:Riboviria
7830:Riboviria
7507:Riboviria
6918:Loebvirae
5758:Adnaviria
5717:Baltimore
5672:Viralzone
4481:: 45–54.
3608:: 45–54.
3557:(1): 35.
3423:: 49–55.
1550:morphemes
1534:leukemias
1475:Diagnosis
1340:NC_020106
1307:NC_018102
1274:NC_014407
1241:NC_014406
1208:NC_009539
1175:NC_009238
1140:NC_001699
1100:NC_001538
1067:NC_024118
1034:NC_020890
1001:NC_015150
966:NC_014361
931:NC_010277
702:, Po for
638:pentamers
607:MMTV-PyMT
592:E3 ligase
486:(ST) and
470:enzymes.
420:host cell
375:promoters
91:Kingdom:
9534:Wikidata
8698:Families
7761:Families
7437:Families
6765:Families
5647:27440877
5598:25635011
5549:11381103
5500:21829355
5449:13819251
5400:13549981
5365:34223353
5357:13064287
5297:19776382
5248:19750217
5197:19499548
5148:19609205
5099:30574884
5091:12352906
5050:10232695
5009:10644084
4973:16626028
4928:16311117
4890:20679358
4882:17131333
4841:11720463
4784:12459734
4749:14566815
4711:16963733
4673:19434930
4632:22461085
4591:23357733
4571:Virology
4556:30328951
4507:28342387
4475:Virology
4456:23276405
4426:Virology
4407:23166671
4367:PLOS ONE
4340:22966183
4291:22740408
4242:27034991
4193:25231015
4144:28040372
4092:17287263
3973:24795478
3935:Pipas JM
3920:23516426
3880:PLOS ONE
3861:21307194
3812:13734654
3804:23593936
3761:20686659
3710:19499546
3634:28342387
3602:Virology
3583:30885224
3532:49351836
3524:29931397
3488:29078783
3437:28284622
3402:46740584
3394:28192039
3333:21562881
3284:16731904
3198:26831433
3149:21609431
3098:20542254
2995:21841310
2946:23954152
2694:25291363
2654:PLOS ONE
2635:20990837
2627:15982744
2592:28174236
2541:21835797
2492:20399955
2468:: 1–51.
2440:23284050
2388:21829355
2337:26474293
2242:17480120
2188:25800023
2139:. ExPASy
2112:18202256
2050:26918152
2024:: 1424.
1996:26985385
1944:26780694
1900:19325891
1846:26667254
1797:23474680
1729:26923930
1667:19 March
1616:28640744
1418:JC virus
1406:BK virus
679:Taxonomy
669:JC virus
665:BK virus
618:oncogene
614:promoter
528:microRNA
503:G1 phase
446:and the
440:JC virus
414:.
331:proteins
323:WU virus
271:.
139:Family:
103:Phylum:
5638:5021401
5589:4319505
5491:3145800
5440:1373056
5288:2773184
5239:2734180
5188:2747737
5139:2932664
4832:2375249
4792:8878662
4547:6157077
4498:9265179
4447:3693558
4398:3498111
4375:Bibcode
4331:3457262
4282:3457274
4233:4811373
4184:4425822
4135:5392424
4083:1866148
4043:4104715
4008:4104714
3964:4334791
3911:3596337
3888:Bibcode
3852:3126223
3752:2912394
3701:6388400
3625:9265179
3574:6423848
3551:Virol J
3479:5658932
3324:3815707
3275:1472594
3189:5217748
3140:3127838
3123:: 255.
3089:2919322
3044:9628860
3035:1170661
2986:3163959
2937:3764649
2897:8917510
2865:Bibcode
2838:8252625
2797:2007706
2789:2153055
2753:9108037
2721:Bibcode
2685:4188587
2662:Bibcode
2532:3187521
2431:3579393
2379:3145800
2328:4608799
2233:1864993
2180:3019556
2143:15 June
2103:2740911
2082:Bibcode
2074:Science
2041:4754031
1987:4792618
1891:2655709
1837:5006224
1788:3928796
1607:5656788
1521:History
1448:monkeys
883:Species
875:genomes
507:S phase
480:nucleus
476:calcium
456:tropism
428:glycans
284:genomes
212:viruses
151:Genera
127:Order:
115:Class:
9647:600030
9634:151341
9621:106551
9595:1PLYVF
7779:Genera
6853:Genera
5645:
5635:
5596:
5586:
5547:
5537:
5498:
5488:
5447:
5437:
5398:
5363:
5355:
5318:
5295:
5285:
5246:
5236:
5195:
5185:
5146:
5136:
5097:
5089:
5048:
5007:
4971:
4961:
4926:
4888:
4880:
4839:
4829:
4790:
4782:
4747:
4709:
4671:
4630:
4589:
4554:
4544:
4505:
4495:
4454:
4444:
4405:
4395:
4353:Yu G,
4338:
4328:
4289:
4279:
4240:
4230:
4191:
4181:
4142:
4132:
4090:
4080:
4041:
4023:Lancet
4006:
3988:Lancet
3971:
3961:
3918:
3908:
3859:
3849:
3810:
3802:
3759:
3749:
3708:
3698:
3632:
3622:
3581:
3571:
3530:
3522:
3486:
3476:
3435:
3400:
3392:
3356:10 May
3331:
3321:
3282:
3272:
3196:
3186:
3147:
3137:
3096:
3086:
3042:
3032:
2993:
2983:
2944:
2934:
2895:
2885:
2836:
2795:
2787:
2751:
2741:
2692:
2682:
2633:
2625:
2590:
2539:
2529:
2490:
2480:
2438:
2428:
2386:
2376:
2335:
2325:
2240:
2230:
2186:
2178:
2110:
2100:
2048:
2038:
1994:
1984:
1942:
1898:
1888:
1844:
1834:
1795:
1785:
1727:
1614:
1604:
1467:, and
1424:, and
1365:LIPyV
1359:Alpha
1336:STLPyV
1030:HPyV12
898:RefSeq
740:Genus
729:Genus
718:Genus
708:clades
671:, and
636:. VP1
517:, but
398:glycan
234:, and
9642:WoRMS
9616:IRMNG
9569:627K6
9380:VII:
7492:III:
5540:99028
5361:S2CID
5095:S2CID
4886:S2CID
4788:S2CID
4218:(2).
3808:S2CID
3781:APMIS
3528:S2CID
3398:S2CID
2888:24011
2793:S2CID
2744:20500
2631:S2CID
2275:(PDF)
2184:S2CID
1420:with
1408:with
1373:2017
1328:Delta
1303:MWPyV
1295:Delta
1270:HPyV7
1262:Delta
1237:HPyV6
1229:Delta
1204:WUPyV
1171:KIPyV
1136:JCPyV
1096:BKPyV
1063:NJPyV
1055:Alpha
1022:Alpha
997:HPyV9
989:Alpha
962:TSPyV
954:Alpha
927:MCPyV
919:Alpha
589:FBXW7
544:lysis
450:with
238:with
216:hosts
77:Realm
70:Virus
9629:NCBI
9608:1935
9603:GBIF
9590:EPPO
9582:8047
9251:VI:
7815:IV:
6892:II:
5680:ICTV
5643:PMID
5594:PMID
5545:PMID
5496:PMID
5445:PMID
5396:PMID
5353:PMID
5316:ISBN
5293:PMID
5244:PMID
5193:PMID
5144:PMID
5087:PMID
5046:PMID
5005:PMID
4969:PMID
4959:ISBN
4924:PMID
4878:PMID
4837:PMID
4780:PMID
4745:PMID
4707:PMID
4669:PMID
4628:PMID
4587:PMID
4552:PMID
4503:PMID
4452:PMID
4403:PMID
4336:PMID
4287:PMID
4238:PMID
4189:PMID
4140:PMID
4088:PMID
4039:PMID
4004:PMID
3969:PMID
3916:PMID
3857:PMID
3800:PMID
3757:PMID
3706:PMID
3660:2008
3630:PMID
3579:PMID
3520:PMID
3484:PMID
3433:PMID
3390:PMID
3358:2021
3329:PMID
3280:PMID
3194:PMID
3145:PMID
3094:PMID
3040:PMID
2991:PMID
2942:PMID
2893:PMID
2834:PMID
2816:Cell
2785:PMID
2769:Cell
2749:PMID
2690:PMID
2623:PMID
2588:PMID
2537:PMID
2488:PMID
2478:ISBN
2436:PMID
2384:PMID
2333:PMID
2238:PMID
2176:PMID
2160:Cell
2145:2015
2108:PMID
2046:PMID
1992:PMID
1940:PMID
1896:PMID
1842:PMID
1793:PMID
1725:PMID
1669:2024
1612:PMID
1560:and
1544:and
1442:SV40
1436:SV40
1344:2013
1311:2012
1278:2010
1245:2010
1212:2007
1196:Beta
1179:2007
1163:Beta
1144:1971
1128:Beta
1104:1971
1088:Beta
1071:2014
1038:2013
1005:2011
970:2010
935:2008
896:NCBI
724:SV40
673:SV40
659:The
611:MMTV
597:The
577:PP2A
571:The
559:The
511:SV40
411:5CPW
363:SV40
268:1SIE
9577:EoL
9564:CoL
8741:V:
7479:RNA
5743:I:
5730:DNA
5633:PMC
5625:doi
5584:PMC
5576:doi
5535:PMC
5527:doi
5486:PMC
5476:doi
5435:PMC
5427:doi
5388:doi
5345:doi
5283:PMC
5275:doi
5271:101
5234:PMC
5224:doi
5183:PMC
5175:doi
5171:125
5134:PMC
5126:doi
5077:doi
5036:doi
4997:doi
4951:doi
4916:doi
4868:doi
4864:120
4827:PMC
4819:doi
4772:doi
4737:doi
4733:107
4699:doi
4659:doi
4655:199
4618:doi
4579:doi
4575:437
4542:PMC
4534:doi
4493:PMC
4483:doi
4479:506
4442:PMC
4434:doi
4430:436
4393:PMC
4383:doi
4326:PMC
4318:doi
4277:PMC
4269:doi
4228:PMC
4220:doi
4179:PMC
4171:doi
4167:211
4130:PMC
4122:doi
4078:PMC
4070:doi
4031:doi
3996:doi
3959:PMC
3951:doi
3947:210
3906:PMC
3896:doi
3847:PMC
3839:doi
3790:doi
3786:121
3747:PMC
3737:doi
3696:PMC
3688:doi
3684:125
3620:PMC
3610:doi
3606:506
3569:PMC
3559:doi
3512:doi
3508:163
3474:PMC
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