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Portal hypertension

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Activation of neurohumoral factors (discussed in the Pathophysiology section) leads to renal vasoconstriction, which results in decreased blood supply to the kidneys and therefore, a decreased glomerular filtration rate. This can be an acute kidney injury (HRS type 1) or a slowly progressive kidney
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Rising portal pressures leads to increased production of vasodilators, defective response to vasoconstrictors, and the formation of new blood vessels all within the splanchnic circulation. All of this is done in order to recruit more blood to sinusoids, thereby promoting more blood flow within the
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Selective shunts select non-intestinal flow to be shunted to the systemic venous drainage while leaving the intestinal venous drainage to continue to pass through the liver. The most well known of this type is the splenorenal. This connects the splenic vein to the left renal vein thus reducing
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are due to a connection between the left gastric vein and the azygos-hemiazygos veins; gastroesophageal varices are due to connections between either the anterior branch of the left gastric vein and esophageal veins or the short gastric & posterior gastric vein and esophageal veins.
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In cirrhosis, there is bacterial overgrowth in the intestinal tract and increased permeability of the intestinal wall. These bacteria (most commonly E. coli & Klebsiella) are able to pass through the intestinal wall and into ascitic fluid, leading to an inflammatory response.
533:, a slow velocity of <16 cm/s in addition to dilatation in the main portal vein are diagnostic of portal hypertension. Other signs of portal hypertension on ultrasound include a portal flow mean velocity of less than 12 cm/s, porto–systemic collateral veins (patent 783:. This use of splanchnic vasoconstrictors increases mean arterial pressure, which increases the amount of blood supplied to the kidneys. This decreases the compensatory neurohumoral response that led to the renal vasoconstriction and improves overall kidney function. 502:
The pathophysiology of non-cirrhotic portal hypertension is most commonly disrupted blood flow to or from the liver. This results in a backing up of blood in either the liver or the vessels supplying it, leading to an increased portal pressure.
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Normally, SECs generate nitric oxide, which has several functions, including the maintenance of vascular tone and prevention of HSC activation. HSC activation results in liver fibrosis, which also predisposes to portal hypertension.
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portal vein, further contributing to portal hypertension. Splanchnic vasodilation results in decreased effective arterial blood volume, causing low blood pressure. To compensate for this low blood pressure, neurohumoral factors (
108:. Normal portal pressure is 1–4 mmHg; clinically insignificant portal hypertension is present at portal pressures 5–9 mmHg; clinically significant portal hypertension is present at portal pressures greater than 10 mmHg. The 806:. Eventually, the heart will no longer be able to maintain this increased cardiac output in the setting of prolonged splanchnic vasodilation. As a result, the heart will not fill with or pump out blood appropriately. 854:
With the advent of transjugular intrahepatic portosystemic shunting (TIPS), portosystemic shunts are less performed. TIPS has the advantage of being easier to perform and doesn't disrupt the liver's vascularity.
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Increased portal pressure leads to dilation of existing vessels and the formation of new vascular connections. These newly formed vascular connections are weak and prone to rupture, which leads to bleeding.
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Primary prevention is given to high-risk groups; secondary prevention is given to anyone who has previously been diagnosed with SBP. Medications for prevention are usually fluoroquinolones or sulfonamides.
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for assessing the severity of portal hypertension. Portal hypertension is defined as HVPG greater than or equal to 5 mmHg and is considered to be clinically significant when HVPG exceeds 10 to 12 mmHg.
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The activation of neurohumoral factors as described in the "Pathophysiology" section results in a high volume state due to sodium and water retention. Additionally, with cirrhosis, there is increased
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Stamm ER, Meier JM, Pokharel SS, Clark T, Glueck DH, Lind KE, Roberts KM (October 2016). "Normal main portal vein diameter measured on CT is larger than the widely referenced upper limit of 13 mm".
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portal system pressure while minimizing any encephalopathy. In an H-shunt, which could be mesocaval (from the superior mesenteric vein to the inferior vena cava) or could be, portocaval (from the
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The management of ascites needs to be gradual to avoid sudden changes in systemic volume status, which can precipitate hepatic encephalopathy, kidney failure, and death. The management includes
751:. Restriction of dietary protein was recommended but this is now refuted by a clinical trial which shows no benefit. Instead, the maintenance of adequate nutrition is now advocated. 1840:
Kimura T, Moriyasu F, Kawasaki T, Someda H, Tamada T, Yamashita Y, et al. (May 1991). "Relationship between esophageal varices and azygos vein evaluated by cineportography".
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Initially, the heart compensates for the decreased effective arterial blood volume that is the result of splanchnic vasodilation by increasing cardiac output, which results in
126:. The signs and symptoms of both cirrhotic and non-cirrhotic portal hypertension are often similar depending on cause, with patients presenting with abdominal swelling due to 779:
Management depends on whether or not patients are in the intensive care unit (ICU). When not in the ICU, patients are given albumin and splanchnic vasoconstrictors such as
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The management of active variceal bleeding includes administering vasoactive drugs (somatostatin, octreotide), endoscopic banding ligation, balloon tamponade and TIPS.
1747:"Introduction to the revised American Association for the Study of Liver Diseases Practice Guideline management of adult patients with ascites due to cirrhosis 2012" 649:
Antibiotic treatment is usually with a third generation cephalosporin (ceftriaxone or cefotaxime) after a diagnostic paracentesis. Patients are also given albumin.
522:(US) is the first-line imaging technique for the diagnosis and follow-up of portal hypertension because it is non-invasive, low-cost and can be performed on-site. 145:
Treatment is directed towards decreasing portal hypertension itself or in the management of its acute and chronic complications. Complications include ascites,
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The pathophysiology of cirrhotic portal hypertension is indicated by increased resistance to blood flow in vessels via different mechanisms. There is
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In portal hypertension, ammonia levels increase and this ammonia can cross the blood brain barrier. As brain cells attempt to clear the ammonia,
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Garbuzenko DV (2016). "Current approaches to the management of patients with liver cirrhosis who have acute esophageal variceal bleeding".
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García-Pagán JC, Gracia-Sancho J, Bosch J (August 2012). "Functional aspects on the pathophysiology of portal hypertension in cirrhosis".
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García-Pagán JC, Gracia-Sancho J, Bosch J (August 2012). "Functional aspects on the pathophysiology of portal hypertension in cirrhosis".
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have been successful in some clinical studies. Patients are also treated with diuretics. Liver transplant may reverse the cardiomyopathy.
4155: 830: 122:(a form of chronic liver failure) is the most common cause of portal hypertension; other, less frequent causes are therefore grouped as 4728: 2993: 246:) or between the liver and the heart (post-hepatic). The most common cause is cirrhosis (chronic liver failure). Other causes include: 847:) a graft, either synthetic or the preferred vein harvested from elsewhere on the patient's body, is connected between the superior 2848: 333: 4500: 3221: 2486:"Mechanisms of adaptation of the hepatic vasculature to the deteriorating conditions of blood circulation in liver cirrhosis" 1262: 3133: 2873: 4505: 238:
The causes for portal hypertension are classified as originating in the portal venous system before it reaches the liver (
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of 13 mm is widely used in this regard, but the diameter is often larger than this is in normal individuals as well.
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Hosking SW, Smart HL, Johnson AG, Triger DR (February 1989). "Anorectal varices, haemorrhoids, and portal hypertension".
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Theise ND (2013-01-01). "Liver, Gallbladder, and Biliary Tract". In Kumar V, Abbas AK, Aster JC, Robbins SL (eds.).
4655: 4272: 3851: 549: 348: 101: 474:). Nitric oxide inhibition has been shown in some studies to increase portal hypertension and hepatic response to 4287: 4148: 3992: 3604: 3587: 3092: 3087: 2964: 4606: 3846: 3802: 3696: 3518: 3117: 323: 972: 4418: 4057: 3903: 4723: 4643: 4348: 3812: 3331: 2939: 2385:"The transjugular intrahepatic portosystemic shunt in the treatment of portal hypertension: current status" 1210:
Bloom S, Kemp W, Lubel J (January 2015). "Portal hypertension: pathophysiology, diagnosis and management".
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A dilated portal vein (diameter of greater than 13 or 15 mm) is a sign of portal hypertension, with a
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Rose CF, Amodio P, Bajaj JS, Dhiman RK, Montagnese S, Taylor-Robinson SD, et al. (December 2020).
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Both pharmacological (non-specific β-blockers, nitrate isosorbide mononitrate, vasopressin such as
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is an endogenous vasodilator and it regulates intrahepatic vascular tone (it is produced from
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Pomier-Layrargues G, Bouchard L, Lafortune M, Bissonnette J, Guérette D, Perreault P (2012).
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is formed excessively, which results in swelling of brain cells and neurologic dysfunction.
494:) are activated, leading to sodium and water retention, and therefore, a high volume state. 4795: 4790: 4594: 4386: 3987: 3931: 3752: 3648: 3231: 3226: 3060: 2978: 2944: 2568:"Contemporary concepts of the medical therapy of portal hypertension under liver cirrhosis" 1418: 760: 748: 582: 491: 354: 328: 301: 158: 914: 8: 4934: 4871: 4638: 4081: 3891: 3784: 3767: 3728: 3653: 3496: 3473: 3466: 3415: 3387: 3309: 3304: 3299: 3216: 2833: 2738: 2037:"Hepatic encephalopathy: Novel insights into classification, pathophysiology and therapy" 542: 515:
Portal hypertension due to cirrhosis resulting in revascularization of the umbilical vein
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Kalluru R, Gadde S, Chikatimalla R, Dasaradhan T, Koneti J, Cherukuri SP (August 2022).
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and the inferior vena cava. The size of this shunt will determine how selective it is.
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Iranpour P, Lall C, Houshyar R, Helmy M, Yang A, Choi JI, et al. (January 2016).
1137: 883: 4576: 4525: 4425: 4071: 4052: 3425: 2760: 2684: 2647: 2628: 2599: 2546: 2517: 2472: 2416: 2365: 2312: 2287: 2246: 2195: 2146: 2080: 2068: 2017: 1968: 1914: 1857: 1822: 1768: 1727: 1678: 1629: 1578: 1529: 1470: 1399: 1364: 1313: 1258: 1227: 1184: 1141: 1106: 1027: 538: 194: 182: 131: 74: 44: 2789: 1869: 1780: 1239: 1196: 1153: 545:), splenomegaly and signs of cirrhosis (including nodularity of the liver surface). 4581: 4230: 4133: 4118: 4038: 4033: 4023: 3885: 3757: 3685: 3503: 3410: 3405: 3335: 3294: 3102: 3067: 2674: 2620: 2589: 2579: 2558: 2538: 2507: 2497: 2462: 2452: 2406: 2396: 2355: 2345: 2277: 2236: 2226: 2185: 2177: 2136: 2128: 2058: 2048: 2007: 1999: 1988:"Management of varices and variceal hemorrhage in liver cirrhosis: a recent update" 1958: 1948: 1904: 1896: 1849: 1812: 1758: 1717: 1709: 1668: 1660: 1619: 1609: 1568: 1560: 1519: 1460: 1452: 1391: 1354: 1344: 1303: 1295: 1219: 1176: 1133: 1096: 1088: 1017: 1009: 602: 590: 295: 204: 49: 2542: 112:
and its branches supply most of the blood and nutrients from the intestine to the
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Fluoroscopic image of transjugular intrahepatic portosystemic shunt (TIPS)
689:) and endoscopic (banding ligation) treatment have similar results. TIPS ( 4896: 4292: 4101: 3863: 3841: 3672: 3592: 3236: 3137: 2890: 2231: 840: 368: 364: 188: 109: 2117:"Management of hepatorenal syndrome in liver cirrhosis: a recent update" 1713: 4812: 4802: 4763: 4707: 4700: 4530: 3877: 3550: 3528: 3173: 3112: 1564: 744: 606: 593:. Combined, this leads to leakage of fluid into the peritoneal cavity. 471: 383: 263: 2711: 1763: 1746: 1417:
Carale J, Azer SA, Mekaroonkamol P (30 November 2017). Anand P (ed.).
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Toxicity (from arsenic, copper, vinyl chloride monomers, mineral oil,
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Imanieh MH, Dehghani SM, Khoshkhui M, Malekpour A (October 2012).
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Portal Hypertension: Diagnostic Imaging and Imaging-Guided Therapy
2212: 1549:"Altered Doppler flow patterns in cirrhosis patients: an overview" 1257:(9th ed.). Philadelphia, PA: Elsevier/Saunders. p. 608. 3513: 3279: 3183: 3155: 2660: 2215:"Cirrhotic Cardiomyopathy: The Interplay Between Liver and Heart" 586: 571: 219: 178: 127: 884:"Portal Hypertension. Learn about Portal Hypertension | Patient" 431: 4173: 3979: 3597: 3483: 2723: 1419:"Portal Hypertension: Practice Essentials, Background, Anatomy" 1333:"Pathophysiology of portal hypertension and esophageal varices" 2610: 1381: 3429: 3159: 732: 210:
Swollen veins on the anterior abdominal wall (referred to as
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Al-Busafi SA, McNabb-Baltar J, Farag A, Hilzenrat N (2012).
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In addition, a widened (dilated) portal vein as seen on a
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Vascular and Endovascular Surgery: A Comprehensive Review
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Bosch J, Berzigotti A, Seijo S, Reverter E (2013-01-28).
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Garbuzenko DV, Arefyev NO, Belov DV (December 2016).
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in diet, diuretics to urinate excess salt and water (
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may raise the suspicion about portal hypertension. A
4163: 2701: 1985: 1508:"The role of ultrasonography in portal hypertension" 624: 497: 1246: 995: 693:) is effective at reducing the rate of rebleeding. 173:Signs and symptoms of portal hypertension include: 2095:"Hepatic Encephalopathy. Free Medical information" 996:Kibrit J, Khan R, Jung BH, Koppe S (August 2018). 2484:Garbuzenko DV, Arefyev NO, Belov DV (June 2016). 69:Splenic vein thrombosis, stenosis of portal vein 4921: 1598:"Clinical manifestations of portal hypertension" 1540: 1330: 1128:. Originally published as Volume 1, Issue 8634. 691:transjugular intrahepatic portosystemic shunting 439: 87:Portosystemic shunts, Nonselective beta-blockers 2331: 2170:Journal of Clinical and Experimental Hepatology 1934: 1646: 1438: 1281: 1081:Journal of Clinical and Experimental Hepatology 1695: 1505: 1209: 1075:Kulkarni AV, Rabiee A, Mohanty A (July 2022). 359:Granulomatous or infiltrative liver diseases ( 4149: 2849: 2163: 1798: 1160: 619:transjugular intrahepatic portosystemic shunt 2955:Esophagogastric junction outflow obstruction 1986:Diaz-Soto MP, Garcia-Tsao G (January 2022). 1799:Huang CH, Lee CH, Chang C (September 2022). 1486: 1484: 552:(HVPG) measurement has been accepted as the 203:), which may lead to lower platelet counts ( 2263: 16:Abnormally increased portal venous pressure 4729:Chronic cerebrospinal venous insufficiency 4156: 4142: 2994:Esophageal intramural pseudodiverticulosis 2856: 2842: 2565: 2528: 965:"Portal hypertension | Disease | Overview" 931: 617:to manually remove the ascitic fluid, and 30: 2678: 2667:Middle East Journal of Digestive Diseases 2646:. 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On 407:Inferior vena cava obstruction 324:Primary sclerosing cholangitis 1: 4419:Aneurysm of sinus of Valsalva 4273:Monckeberg's arteriosclerosis 3904:Sphincter of Oddi dysfunction 2543:10.1185/03007995.2015.1124846 2270:Texas Heart Institute Journal 1138:10.1016/S0140-6736(89)91724-8 858: 727:A treatment plan may involve 652: 596: 440:Cirrhotic portal hypertension 378:, azathioprine, dacarbazine, 281:(increased portal blood flow) 271:(increased portal blood flow) 181:, which is free fluid in the 4724:Chronic venous insufficiency 4349:Aortoiliac occlusive disease 3813:Postcholecystectomy syndrome 3332:Intestinal pseudoobstruction 2940:Esophageal motility disorder 820: 585:and decreased production of 506: 7: 4739:Inferior vena cava syndrome 4734:Superior vena cava syndrome 4461:Vertebral artery dissection 4451:Intracranial berry aneurysm 2490:World Journal of Hepatology 2445:World Journal of Hepatology 1300:10.1016/j.jhepr.2021.100316 1050:MSD Manual Consumer Version 815:Non-selective beta blockers 446:sinusoidal endothelial cell 344:Congenital hepatic fibrosis 242:causes), within the liver ( 10: 4956: 4840:Hypertensive heart disease 4491:Arteriovenous malformation 4466:Familial aortic dissection 3798:Gallstone / Cholelithiasis 3322:Functional colonic disease 3118:Zollinger–Ellison syndrome 2625:10.1016/j.jhep.2012.03.007 2566:Garbuzenko DV (May 2015). 2182:10.1016/j.jceh.2021.08.016 2054:10.1016/j.jhep.2020.07.013 1506:Al-Nakshabandi NA (2006). 1441:"Hypotension in Cirrhosis" 1396:10.1016/j.jhep.2012.03.007 1093:10.1016/j.jceh.2022.03.002 790: 758: 703: 628: 589:, which lead to decreased 569: 565: 4895: 4865:Renovascular hypertension 4830: 4821: 4808:Hepatic artery thrombosis 4756: 4716: 4671: 4575: 4557: 4548: 4516: 4476: 4456:Carotid artery dissection 4409:Abdominal aortic aneurysm 4381: 4341: 4318: 4259:Intermittent claudication 4229: 4222:Peripheral artery disease 4220: 4190: 4172: 4092: 3971: 3912: 3826: 3783: 3629: 3620: 3573: 3527: 3482: 3368: 3255: 3145: 3132: 3007: 2999:Acute esophageal necrosis 2881: 2872: 2775: 2705: 2133:10.1177/17562848221102679 2004:10.1177/17562848221101712 1212:Internal Medicine Journal 1181:10.1007/s00261-016-0785-9 969:rarediseases.info.nih.gov 804:high-output heart failure 415:constrictive pericarditis 411:Right-sided heart failure 363:, mucopolysaccharidosis, 317:Primary biliary cirrhosis 233: 83: 73: 65: 55: 43: 38: 29: 24: 4850:Hypertensive nephropathy 4663:Post-thrombotic syndrome 4644:Paget–Schroetter disease 4436:Coronary artery aneurysm 4414:Thoracic aortic aneurysm 3098:Gastric dumping syndrome 2973:Laryngopharyngeal reflux 2960:Diffuse esophageal spasm 2585:10.3748/wjg.v21.i20.6117 1954:10.3748/wjg.v18.i11.1166 1745:Runyon BA (April 2013). 96:is defined as increased 4905:Orthostatic hypotension 4887:White coat hypertension 4364:Fibromuscular dysplasia 4328:Carotid artery stenosis 3714:Alcoholic liver disease 3247:Bile acid malabsorption 3191:Peptic (duodenal) ulcer 2458:10.4254/wjh.v8.i36.1602 2305:Moore WS (2012-11-23). 1525:10.4103/1319-3767.29750 1255:Robbins basic pathology 531:Doppler ultrasonography 307:chronic viral hepatitis 199:Increased spleen size ( 4877:Pulmonary hypertension 4860:Secondary hypertension 4855:Essential hypertension 4845:Hypertensive emergency 4686:Portacaval anastomosis 4622:Portal vein thrombosis 4264:Critical limb ischemia 4165:Cardiovascular disease 3724:Hepatic encephalopathy 3108:Buried bumper syndrome 3039:Peptic (gastric) ulcer 2923:Mallory–Weiss syndrome 2866:human digestive system 2640:Rossi P (2012-12-06). 2503:10.4254/wjh.v8.i16.665 1854:10.1002/hep.1840130510 1653:Clinical Liver Disease 1445:Clinical Liver Disease 1014:10.1055/s-0038-1660793 919:emedicine.medscape.com 835: 771:failure (HRS type 2). 706:Hepatic encephalopathy 700:Hepatic encephalopathy 516: 436: 397:Veno-occlusive disease 256:Portal vein thrombosis 155:hepatic encephalopathy 136:elevated liver enzymes 98:portal venous pressure 4882:Systolic hypertension 4627:Renal vein thrombosis 4486:Arteriovenous fistula 4478:Vascular malformation 4446:Intracranial aneurysm 4333:Renal artery stenosis 3949:Pancreatic pseudocyst 3818:Porcelain gallbladder 2930:Zenker's diverticulum 2613:Journal of Hepatology 2338:ISRN Gastroenterology 2127:: 17562848221102679. 2041:Journal of Hepatology 1998:: 17562848221101712. 1901:10.3350/cmh.2017.0064 1883:Seo YS (March 2018). 1818:10.3390/livers2030018 1649:"Unexplained ascites" 1384:Journal of Hepatology 940:"Portal hypertension" 833: 514: 450:hepatic stellate cell 434: 269:Arteriovenous fistula 4796:Paradoxical embolism 4791:Cholesterol embolism 4617:May–Thurner syndrome 4612:Budd–Chiari syndrome 4595:Deep vein thrombosis 4590:primarily lower limb 4369:Raynaud's phenomenon 3753:Hepatorenal syndrome 3692:Budd–Chiari syndrome 3649:Autoimmune hepatitis 3474:Intestinal adhesions 3232:Short bowel syndrome 3061:Functional dyspepsia 2979:Esophageal stricture 2945:Nutcracker esophagus 2232:10.7759/cureus.27969 826:Portosystemic shunts 761:Hepatorenal syndrome 755:Hepatorenal syndrome 583:hydrostatic pressure 420:Budd–Chiari syndrome 329:Chronic pancreatitis 302:alcohol use disorder 159:hepatorenal syndrome 4872:Benign hypertension 3892:Choledocholithiasis 3763:Metabolic disorders 3729:Acute liver failure 3702:Portal hypertension 3654:Alcoholic hepatitis 3497:Radiation proctitis 3416:Mesenteric ischemia 3388:Gastroenterocolitis 3217:Blind loop syndrome 3027:MĂ©nĂ©trier's disease 2935:Barrett's esophagus 2825:Portal hypertension 2402:10.1155/2012/167868 2351:10.1155/2013/464053 1714:10.1503/cmaj.051700 1615:10.1155/2012/203794 1350:10.1155/2012/895787 1169:Abdominal Radiology 662:Variceal hemorrhage 543:short gastric veins 448:dysfunction (SEC), 393:Fatty liver disease 140:low platelet counts 94:Portal hypertension 25:Portal hypertension 4786:Pulmonary embolism 4696:Esophageal varices 4634:upper limb / torso 4278:Arteriolosclerosis 4067:Undefined location 4058:Grynfeltt–Lesshaft 3959:Pancreatic fistula 3942:Pancreatic abscess 3897:Biliary dyskinesia 3868:Mirizzi's syndrome 3369:Large and/or small 3049:Dieulafoy's lesion 2918:Boerhaave syndrome 2776:External resources 2101:. 11 January 2022. 1565:10.14366/usg.15020 836: 674:Esophageal varices 535:paraumbilical vein 517: 452:(HSC) activation, 437: 402:Posthepatic causes 169:Signs and symptoms 4917: 4916: 4913: 4912: 4757:Arteries or veins 4752: 4751: 4577:Venous thrombosis 4544: 4543: 4526:Cherry hemangioma 4426:Aortic dissection 4377: 4376: 4212:Buerger's disease 4131: 4130: 4127: 4126: 3967: 3966: 3569: 3568: 3426:Bowel obstruction 3128: 3127: 2802: 2801: 2578:(20): 6117–6126. 2451:(36): 1602–1609. 1947:(11): 1166–1175. 1764:10.1002/hep.26359 1708:(10): 1433–1443. 1264:978-1-4377-1781-5 1224:10.1111/imj.12590 1175:(10): 1931–1936. 1132:(8634): 349–352. 250:Prehepatic causes 195:Anorectal varices 183:peritoneal cavity 132:vomiting of blood 91: 90: 75:Diagnostic method 19:Medical condition 4947: 4828: 4827: 4639:Mondor's disease 4582:Thrombophlebitis 4555: 4554: 4231:Arteriosclerosis 4227: 4226: 4188: 4187: 4158: 4151: 4144: 4135: 4134: 4119:Pneumoperitoneum 3976: 3975: 3886:Common bile duct 3768:Wilson's disease 3758:Peliosis hepatis 3627: 3626: 3504:Proctalgia fugax 3411:Abdominal angina 3336:Ogilvie syndrome 3285:Pseudomembranous 3143: 3142: 3103:Gastric volvulus 3068:Pyloric stenosis 2879: 2878: 2864:Diseases of the 2858: 2851: 2844: 2835: 2834: 2811: 2810: 2703: 2702: 2692: 2682: 2657: 2636: 2607: 2597: 2587: 2562: 2525: 2515: 2505: 2480: 2470: 2460: 2425: 2424: 2414: 2404: 2380: 2374: 2373: 2363: 2353: 2329: 2323: 2322: 2302: 2296: 2295: 2285: 2261: 2255: 2254: 2244: 2234: 2210: 2204: 2203: 2193: 2161: 2155: 2154: 2144: 2112: 2103: 2102: 2099:www.patient.info 2091: 2085: 2084: 2066: 2056: 2047:(6): 1526–1547. 2032: 2026: 2025: 2015: 1983: 1977: 1976: 1966: 1956: 1932: 1923: 1922: 1912: 1880: 1874: 1873: 1837: 1831: 1830: 1820: 1796: 1785: 1784: 1766: 1757:(4): 1651–1653. 1742: 1736: 1735: 1725: 1693: 1687: 1686: 1676: 1644: 1638: 1637: 1627: 1617: 1593: 1587: 1586: 1576: 1544: 1538: 1537: 1527: 1503: 1497: 1496: 1488: 1479: 1478: 1468: 1436: 1427: 1426: 1414: 1408: 1407: 1379: 1373: 1372: 1362: 1352: 1328: 1322: 1321: 1311: 1279: 1270: 1268: 1250: 1244: 1243: 1207: 1201: 1200: 1164: 1158: 1157: 1121: 1115: 1114: 1104: 1087:(4): 1184–1199. 1072: 1061: 1060: 1058: 1056: 1042: 1036: 1035: 1025: 993: 984: 983: 981: 980: 971:. Archived from 961: 955: 954: 952: 950: 935: 929: 928: 926: 925: 911: 898: 897: 895: 894: 880: 843:to the inferior 603:salt restriction 591:oncotic pressure 456:activation, and 205:thrombocytopenia 187:Vomiting blood ( 50:Gastroenterology 34: 22: 21: 4955: 4954: 4950: 4949: 4948: 4946: 4945: 4944: 4920: 4919: 4918: 4909: 4891: 4817: 4774:Microangiopathy 4769:Macroangiopathy 4748: 4712: 4681:Gastric varices 4667: 4580: 4571: 4540: 4512: 4472: 4404:Aortic aneurysm 4390: 4373: 4359:Erythromelalgia 4337: 4314: 4239:Atherosclerosis 4216: 4180: 4168: 4162: 4132: 4123: 4088: 4077:Internal hernia 3963: 3908: 3873:Biliary fistula 3831: 3822: 3808:Adenomyomatosis 3803:Cholesterolosis 3779: 3773:Hemochromatosis 3644:Viral hepatitis 3616: 3565: 3523: 3509:Rectal prolapse 3478: 3445:Fecal impaction 3435:Intussusception 3398:Crohn's disease 3364: 3347:Toxic megacolon 3259: 3257:Large intestine 3251: 3196:Curling's ulcer 3149: 3147:Small intestine 3136: 3124: 3032:Gastroenteritis 3003: 2868: 2862: 2832: 2831: 2830: 2812: 2808: 2803: 2798: 2797: 2771: 2770: 2714: 2700: 2695: 2654: 2496:(16): 665–672. 2434: 2432:Further reading 2429: 2428: 2381: 2377: 2330: 2326: 2319: 2303: 2299: 2262: 2258: 2211: 2207: 2162: 2158: 2113: 2106: 2093: 2092: 2088: 2033: 2029: 1984: 1980: 1933: 1926: 1881: 1877: 1838: 1834: 1797: 1788: 1743: 1739: 1694: 1690: 1665:10.1002/cld.537 1645: 1641: 1594: 1590: 1553:Ultrasonography 1545: 1541: 1504: 1500: 1489: 1482: 1457:10.1002/cld.764 1437: 1430: 1415: 1411: 1380: 1376: 1329: 1325: 1280: 1273: 1265: 1251: 1247: 1208: 1204: 1165: 1161: 1122: 1118: 1073: 1064: 1054: 1052: 1044: 1043: 1039: 994: 987: 978: 976: 963: 962: 958: 948: 946: 936: 932: 923: 921: 913: 912: 901: 892: 890: 882: 881: 866: 861: 849:mesenteric vein 828: 823: 812: 800: 795: 789: 777: 768: 763: 757: 725: 713: 708: 702: 683: 669: 664: 655: 647: 638: 633: 627: 599: 579: 574: 568: 563: 520:Ultrasonography 509: 500: 442: 429: 427:Pathophysiology 389:Viral hepatitis 361:Gaucher disease 339:Schistosomiasis 312:biliary atresia 236: 171: 104:greater than 5 79:Ultrasonography 20: 17: 12: 11: 5: 4953: 4943: 4942: 4937: 4932: 4915: 4914: 4911: 4910: 4908: 4907: 4901: 4899: 4893: 4892: 4890: 4889: 4884: 4879: 4874: 4869: 4868: 4867: 4857: 4852: 4847: 4842: 4836: 4834: 4825: 4823:Blood pressure 4819: 4818: 4816: 4815: 4810: 4805: 4800: 4799: 4798: 4793: 4788: 4778: 4777: 4776: 4771: 4760: 4758: 4754: 4753: 4750: 4749: 4747: 4746: 4741: 4736: 4731: 4726: 4720: 4718: 4714: 4713: 4711: 4710: 4705: 4704: 4703: 4698: 4693: 4683: 4677: 4675: 4673:Varicose veins 4669: 4668: 4666: 4665: 4660: 4659: 4658: 4648: 4647: 4646: 4641: 4631: 4630: 4629: 4624: 4619: 4614: 4609: 4599: 4598: 4597: 4586: 4584: 4573: 4572: 4570: 4569: 4563: 4561: 4552: 4546: 4545: 4542: 4541: 4539: 4538: 4536:Spider angioma 4533: 4528: 4522: 4520: 4518:Vascular nevus 4514: 4513: 4511: 4510: 4509: 4508: 4503: 4496:Telangiectasia 4493: 4488: 4482: 4480: 4474: 4473: 4471: 4470: 4469: 4468: 4463: 4458: 4453: 4448: 4438: 4433: 4431:Aortic rupture 4428: 4423: 4422: 4421: 4416: 4411: 4396: 4394: 4392:pseudoaneurysm 4379: 4378: 4375: 4374: 4372: 4371: 4366: 4361: 4356: 4351: 4345: 4343: 4339: 4338: 4336: 4335: 4330: 4324: 4322: 4316: 4315: 4313: 4312: 4311: 4310: 4305: 4303:Oxycholesterol 4300: 4295: 4290: 4285: 4275: 4269: 4268: 4267: 4266: 4261: 4256: 4251: 4246: 4235: 4233: 4224: 4218: 4217: 4215: 4214: 4209: 4208: 4207: 4196: 4194: 4185: 4170: 4169: 4161: 4160: 4153: 4146: 4138: 4129: 4128: 4125: 4124: 4122: 4121: 4116: 4114:Hemoperitoneum 4111: 4110: 4109: 4098: 4096: 4090: 4089: 4087: 4086: 4085: 4084: 4079: 4074: 4063: 4062: 4061: 4060: 4055: 4042: 4041: 4036: 4031: 4026: 4021: 4020: 4019: 4014: 4003: 4002: 3997: 3996: 3995: 3984: 3982: 3973: 3969: 3968: 3965: 3964: 3962: 3961: 3956: 3951: 3946: 3945: 3944: 3939: 3934: 3929: 3918: 3916: 3910: 3909: 3907: 3906: 3901: 3900: 3899: 3894: 3881: 3880: 3875: 3870: 3861: 3860: 3859: 3854: 3849: 3838: 3836: 3824: 3823: 3821: 3820: 3815: 3810: 3805: 3800: 3795: 3789: 3787: 3781: 3780: 3778: 3777: 3776: 3775: 3770: 3760: 3755: 3750: 3749: 3748: 3743: 3733: 3732: 3731: 3726: 3716: 3711: 3710: 3709: 3704: 3699: 3694: 3682: 3681: 3680: 3670: 3669: 3668: 3658: 3657: 3656: 3651: 3646: 3635: 3633: 3624: 3618: 3617: 3615: 3614: 3613: 3612: 3602: 3601: 3600: 3595: 3585: 3583:Blood in stool 3579: 3577: 3571: 3570: 3567: 3566: 3564: 3563: 3558: 3556:Anal dysplasia 3553: 3548: 3543: 3533: 3531: 3525: 3524: 3522: 3521: 3516: 3511: 3506: 3501: 3500: 3499: 3488: 3486: 3480: 3479: 3477: 3476: 3471: 3470: 3469: 3459: 3458: 3457: 3447: 3442: 3437: 3432: 3423: 3421:Angiodysplasia 3418: 3413: 3402: 3401: 3400: 3390: 3385: 3384: 3383: 3372: 3370: 3366: 3365: 3363: 3362: 3356:Diverticulosis 3352:Diverticulitis 3349: 3340: 3339: 3338: 3329: 3319: 3314: 3313: 3312: 3307: 3302: 3297: 3292: 3287: 3277: 3271: 3269: 3253: 3252: 3250: 3249: 3244: 3242:Milroy disease 3239: 3234: 3229: 3224: 3219: 3214: 3212:Tropical sprue 3209: 3200: 3199: 3198: 3188: 3187: 3186: 3181: 3176: 3165: 3163: 3140: 3134:Lower GI tract 3130: 3129: 3126: 3125: 3123: 3122: 3121: 3120: 3110: 3105: 3100: 3095: 3090: 3085: 3080: 3075: 3070: 3065: 3064: 3063: 3053: 3052: 3051: 3046: 3036: 3035: 3034: 3029: 3024: 3013: 3011: 3005: 3004: 3002: 3001: 2996: 2991: 2986: 2981: 2976: 2970: 2969: 2968: 2962: 2957: 2952: 2947: 2937: 2932: 2927: 2926: 2925: 2920: 2910: 2909: 2908: 2903: 2898: 2887: 2885: 2876: 2874:Upper GI tract 2870: 2869: 2861: 2860: 2853: 2846: 2838: 2813: 2806: 2805: 2804: 2800: 2799: 2796: 2795: 2780: 2779: 2777: 2773: 2772: 2769: 2768: 2757: 2746: 2731: 2715: 2710: 2709: 2707: 2706:Classification 2699: 2698:External links 2696: 2694: 2693: 2673:(4): 206–210. 2658: 2652: 2637: 2619:(2): 458–461. 2608: 2563: 2537:(3): 467–475. 2526: 2481: 2435: 2433: 2430: 2427: 2426: 2375: 2324: 2318:978-1455753864 2317: 2297: 2276:(4): 549–554. 2256: 2205: 2176:(1): 186–199. 2156: 2104: 2086: 2027: 1978: 1924: 1875: 1848:(5): 858–864. 1832: 1811:(3): 214–232. 1786: 1737: 1688: 1639: 1588: 1539: 1518:(3): 111–117. 1498: 1480: 1451:(6): 149–153. 1428: 1409: 1390:(2): 458–461. 1374: 1323: 1271: 1263: 1245: 1202: 1159: 1116: 1062: 1037: 1008:(3): 153–159. 985: 956: 930: 899: 863: 862: 860: 857: 827: 824: 822: 819: 811: 808: 799: 796: 793:Cardiomyopathy 791:Main article: 788: 787:Cardiomyopathy 785: 776: 773: 767: 764: 759:Main article: 756: 753: 724: 721: 712: 709: 704:Main article: 701: 698: 682: 679: 668: 665: 663: 660: 654: 651: 646: 643: 637: 634: 629:Main article: 626: 623: 611:spironolactone 598: 595: 578: 575: 570:Main article: 567: 564: 562: 559: 508: 505: 499: 496: 476:norepinephrine 441: 438: 428: 425: 424: 423: 417: 408: 399: 398: 395: 390: 387: 372: 357: 355:space of Disse 351: 346: 341: 336: 331: 326: 321: 320: 319: 314: 309: 304: 286:Hepatic causes 283: 282: 272: 266: 258: 235: 232: 216: 215: 208: 197: 192: 185: 170: 167: 163:cardiomyopathy 89: 88: 85: 81: 80: 77: 71: 70: 67: 63: 62: 59: 53: 52: 47: 41: 40: 36: 35: 27: 26: 18: 15: 9: 6: 4: 3: 2: 4952: 4941: 4938: 4936: 4933: 4931: 4928: 4927: 4925: 4906: 4903: 4902: 4900: 4898: 4894: 4888: 4885: 4883: 4880: 4878: 4875: 4873: 4870: 4866: 4863: 4862: 4861: 4858: 4856: 4853: 4851: 4848: 4846: 4843: 4841: 4838: 4837: 4835: 4833: 4829: 4826: 4824: 4820: 4814: 4811: 4809: 4806: 4804: 4801: 4797: 4794: 4792: 4789: 4787: 4784: 4783: 4782: 4779: 4775: 4772: 4770: 4767: 4766: 4765: 4762: 4761: 4759: 4755: 4745: 4742: 4740: 4737: 4735: 4732: 4730: 4727: 4725: 4722: 4721: 4719: 4715: 4709: 4706: 4702: 4699: 4697: 4694: 4692: 4691:Caput medusae 4689: 4688: 4687: 4684: 4682: 4679: 4678: 4676: 4674: 4670: 4664: 4661: 4657: 4654: 4653: 4652: 4649: 4645: 4642: 4640: 4637: 4636: 4635: 4632: 4628: 4625: 4623: 4620: 4618: 4615: 4613: 4610: 4608: 4605: 4604: 4603: 4600: 4596: 4593: 4592: 4591: 4588: 4587: 4585: 4583: 4578: 4574: 4568: 4565: 4564: 4562: 4560: 4556: 4553: 4551: 4547: 4537: 4534: 4532: 4529: 4527: 4524: 4523: 4521: 4519: 4515: 4507: 4504: 4502: 4499: 4498: 4497: 4494: 4492: 4489: 4487: 4484: 4483: 4481: 4479: 4475: 4467: 4464: 4462: 4459: 4457: 4454: 4452: 4449: 4447: 4444: 4443: 4442: 4439: 4437: 4434: 4432: 4429: 4427: 4424: 4420: 4417: 4415: 4412: 4410: 4407: 4406: 4405: 4401: 4398: 4397: 4395: 4393: 4388: 4384: 4380: 4370: 4367: 4365: 4362: 4360: 4357: 4355: 4354:Degos disease 4352: 4350: 4347: 4346: 4344: 4340: 4334: 4331: 4329: 4326: 4325: 4323: 4321: 4317: 4309: 4306: 4304: 4301: 4299: 4296: 4294: 4291: 4289: 4286: 4284: 4281: 4280: 4279: 4276: 4274: 4271: 4270: 4265: 4262: 4260: 4257: 4255: 4252: 4250: 4247: 4245: 4242: 4241: 4240: 4237: 4236: 4234: 4232: 4228: 4225: 4223: 4219: 4213: 4210: 4206: 4203: 4202: 4201: 4198: 4197: 4195: 4193: 4189: 4186: 4184: 4179: 4175: 4171: 4166: 4159: 4154: 4152: 4147: 4145: 4140: 4139: 4136: 4120: 4117: 4115: 4112: 4108: 4105: 4104: 4103: 4100: 4099: 4097: 4095: 4091: 4083: 4080: 4078: 4075: 4073: 4070: 4069: 4068: 4065: 4064: 4059: 4056: 4054: 4051: 4050: 4049: 4048: 4044: 4043: 4040: 4037: 4035: 4032: 4030: 4027: 4025: 4022: 4018: 4015: 4013: 4010: 4009: 4008: 4005: 4004: 4001: 3998: 3994: 3991: 3990: 3989: 3988:Diaphragmatic 3986: 3985: 3983: 3981: 3977: 3974: 3970: 3960: 3957: 3955: 3952: 3950: 3947: 3943: 3940: 3938: 3935: 3933: 3930: 3928: 3925: 3924: 3923: 3920: 3919: 3917: 3915: 3911: 3905: 3902: 3898: 3895: 3893: 3890: 3889: 3888: 3887: 3883: 3882: 3879: 3876: 3874: 3871: 3869: 3865: 3862: 3858: 3855: 3853: 3850: 3848: 3845: 3844: 3843: 3840: 3839: 3837: 3835: 3829: 3825: 3819: 3816: 3814: 3811: 3809: 3806: 3804: 3801: 3799: 3796: 3794: 3793:Cholecystitis 3791: 3790: 3788: 3786: 3782: 3774: 3771: 3769: 3766: 3765: 3764: 3761: 3759: 3756: 3754: 3751: 3747: 3744: 3742: 3739: 3738: 3737: 3736:Liver abscess 3734: 3730: 3727: 3725: 3722: 3721: 3720: 3719:Liver failure 3717: 3715: 3712: 3708: 3705: 3703: 3700: 3698: 3695: 3693: 3690: 3689: 3688: 3687: 3683: 3679: 3676: 3675: 3674: 3671: 3667: 3664: 3663: 3662: 3659: 3655: 3652: 3650: 3647: 3645: 3642: 3641: 3640: 3637: 3636: 3634: 3632: 3628: 3625: 3623: 3619: 3611: 3608: 3607: 3606: 3603: 3599: 3596: 3594: 3591: 3590: 3589: 3586: 3584: 3581: 3580: 3578: 3576: 3572: 3562: 3559: 3557: 3554: 3552: 3549: 3547: 3544: 3542: 3538: 3535: 3534: 3532: 3530: 3526: 3520: 3517: 3515: 3512: 3510: 3507: 3505: 3502: 3498: 3495: 3494: 3493: 3490: 3489: 3487: 3485: 3481: 3475: 3472: 3468: 3465: 3464: 3463: 3460: 3456: 3453: 3452: 3451: 3448: 3446: 3443: 3441: 3438: 3436: 3433: 3431: 3427: 3424: 3422: 3419: 3417: 3414: 3412: 3408: 3407: 3403: 3399: 3396: 3395: 3394: 3391: 3389: 3386: 3382: 3379: 3378: 3377: 3376:Enterocolitis 3374: 3373: 3371: 3367: 3361: 3357: 3353: 3350: 3348: 3344: 3341: 3337: 3333: 3330: 3328: 3325: 3324: 3323: 3320: 3318: 3315: 3311: 3308: 3306: 3303: 3301: 3298: 3296: 3293: 3291: 3288: 3286: 3283: 3282: 3281: 3278: 3276: 3273: 3272: 3270: 3267: 3263: 3258: 3254: 3248: 3245: 3243: 3240: 3238: 3235: 3233: 3230: 3228: 3225: 3223: 3220: 3218: 3215: 3213: 3210: 3208: 3204: 3203:Malabsorption 3201: 3197: 3194: 3193: 3192: 3189: 3185: 3182: 3180: 3177: 3175: 3172: 3171: 3170: 3167: 3166: 3164: 3161: 3157: 3153: 3148: 3144: 3141: 3139: 3135: 3131: 3119: 3116: 3115: 3114: 3111: 3109: 3106: 3104: 3101: 3099: 3096: 3094: 3091: 3089: 3086: 3084: 3081: 3079: 3078:Gastroparesis 3076: 3074: 3071: 3069: 3066: 3062: 3059: 3058: 3057: 3054: 3050: 3047: 3045: 3044:Cushing ulcer 3042: 3041: 3040: 3037: 3033: 3030: 3028: 3025: 3023: 3020: 3019: 3018: 3015: 3014: 3012: 3010: 3006: 3000: 2997: 2995: 2992: 2990: 2989:Megaesophagus 2987: 2985: 2982: 2980: 2977: 2974: 2971: 2966: 2963: 2961: 2958: 2956: 2953: 2951: 2948: 2946: 2943: 2942: 2941: 2938: 2936: 2933: 2931: 2928: 2924: 2921: 2919: 2916: 2915: 2914: 2911: 2907: 2904: 2902: 2899: 2897: 2894: 2893: 2892: 2889: 2888: 2886: 2884: 2880: 2877: 2875: 2871: 2867: 2859: 2854: 2852: 2847: 2845: 2840: 2839: 2836: 2828: 2827: 2826: 2820: 2816: 2794: 2791: 2787: 2786: 2782: 2781: 2778: 2774: 2767: 2763: 2762: 2758: 2756: 2752: 2751: 2747: 2745: 2741: 2740: 2736: 2732: 2730: 2726: 2725: 2721: 2717: 2716: 2713: 2708: 2704: 2690: 2686: 2681: 2676: 2672: 2668: 2664: 2659: 2655: 2653:9783642571169 2649: 2645: 2644: 2638: 2634: 2630: 2626: 2622: 2618: 2614: 2609: 2605: 2601: 2596: 2591: 2586: 2581: 2577: 2573: 2569: 2564: 2560: 2556: 2552: 2548: 2544: 2540: 2536: 2532: 2527: 2523: 2519: 2514: 2509: 2504: 2499: 2495: 2491: 2487: 2482: 2478: 2474: 2469: 2464: 2459: 2454: 2450: 2446: 2442: 2437: 2436: 2422: 2418: 2413: 2408: 2403: 2398: 2394: 2390: 2386: 2379: 2371: 2367: 2362: 2357: 2352: 2347: 2343: 2339: 2335: 2328: 2320: 2314: 2310: 2309: 2301: 2293: 2289: 2284: 2279: 2275: 2271: 2267: 2260: 2252: 2248: 2243: 2238: 2233: 2228: 2225:(8): e27969. 2224: 2220: 2216: 2209: 2201: 2197: 2192: 2187: 2183: 2179: 2175: 2171: 2167: 2160: 2152: 2148: 2143: 2138: 2134: 2130: 2126: 2122: 2118: 2111: 2109: 2100: 2096: 2090: 2082: 2078: 2074: 2070: 2065: 2064:10044/1/84685 2060: 2055: 2050: 2046: 2042: 2038: 2031: 2023: 2019: 2014: 2009: 2005: 2001: 1997: 1993: 1989: 1982: 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300: 299: 297: 293: 290: 289: 288: 287: 280: 279:hypersplenism 276: 273: 270: 267: 265: 262: 259: 257: 254: 253: 252: 251: 247: 245: 241: 231: 229: 225: 221: 213: 212:caput medusae 209: 206: 202: 198: 196: 193: 190: 186: 184: 180: 176: 175: 174: 166: 164: 160: 156: 152: 148: 143: 141: 137: 133: 129: 125: 121: 117: 115: 111: 107: 103: 99: 95: 86: 82: 78: 76: 72: 68: 64: 60: 58: 54: 51: 48: 46: 42: 37: 33: 28: 23: 4940:Hypertension 4832:Hypertension 4744:Venous ulcer 4650: 4633: 4601: 4589: 4559:Inflammation 4440: 4399: 4288:Hyperplastic 4249:Fatty streak 4192:Inflammation 4066: 4045: 3922:Pancreatitis 3884: 3834:biliary tree 3707:Nutmeg liver 3701: 3684: 3610:Hematochezia 3561:Pruritus ani 3546:Anal abscess 3541:Anal fistula 3537:Anal fissure 3450:Constipation 3404: 3275:Appendicitis 3083:Gastroptosis 3073:Achlorhydria 2912: 2901:Eosinophilic 2823: 2822: 2821:profile for 2818: 2783: 2759: 2748: 2733: 2718: 2670: 2666: 2642: 2616: 2612: 2575: 2571: 2534: 2530: 2493: 2489: 2448: 2444: 2392: 2388: 2378: 2341: 2337: 2327: 2307: 2300: 2273: 2269: 2259: 2222: 2218: 2208: 2173: 2169: 2159: 2124: 2120: 2098: 2089: 2044: 2040: 2030: 1995: 1991: 1981: 1944: 1940: 1895:(1): 20–42. 1892: 1888: 1878: 1845: 1841: 1835: 1808: 1804: 1754: 1750: 1740: 1705: 1701: 1691: 1659:(3): 53–56. 1656: 1652: 1642: 1605: 1601: 1591: 1556: 1552: 1542: 1515: 1511: 1501: 1448: 1444: 1422: 1412: 1387: 1383: 1377: 1340: 1336: 1326: 1291: 1288:JHEP Reports 1287: 1254: 1248: 1218:(1): 16–26. 1215: 1211: 1205: 1172: 1168: 1162: 1129: 1125: 1119: 1084: 1080: 1053:. Retrieved 1049: 1040: 1005: 1001: 977:. Retrieved 973:the original 968: 959: 947:. Retrieved 943: 933: 922:. Retrieved 918: 891:. Retrieved 887: 853: 837: 813: 801: 798:Pathogenesis 781:terlipressin 778: 769: 766:Pathogenesis 726: 714: 711:Pathogenesis 695: 687:terlipressin 684: 670: 667:Pathogenesis 656: 648: 639: 636:Pathogenesis 615:paracentesis 600: 580: 577:Pathogenesis 547: 524: 518: 501: 480: 468:Nitric oxide 466: 462: 460:activation. 454:Kupffer cell 443: 413:, e.g. from 401: 400: 380:methotrexate 353:Fibrosis of 285: 284: 275:Splenomegaly 261:Splenic vein 249: 248: 244:intrahepatic 243: 239: 237: 228:cutoff value 217: 201:splenomegaly 172: 153:hemorrhage, 144: 123: 118: 93: 92: 4897:Hypotension 4441:head / neck 4293:Cholesterol 4183:capillaries 4102:Peritonitis 3864:Cholestasis 3842:Cholangitis 3785:Gallbladder 3673:Fatty liver 3593:Hematemesis 3575:GI bleeding 3381:Necrotizing 3310:Lymphocytic 3305:Collagenous 3300:Microscopic 3237:Steatorrhea 3138:Enteropathy 2984:Inlet patch 2906:Herpetiform 2891:Esophagitis 1559:(1): 3–12. 944:Radiopaedia 938:D'Souza D. 841:portal vein 527:sensitivity 369:amyloidosis 365:sarcoidosis 189:hematemesis 110:portal vein 4935:Hepatology 4924:Categories 4813:Vasculitis 4803:Thrombosis 4764:Angiopathy 4708:Varicocele 4701:Hemorrhoid 4531:Halo nevus 4387:dissection 4178:arterioles 4094:Peritoneal 4072:Incisional 3993:Congenital 3937:Hereditary 3914:Pancreatic 3878:Haemobilia 3551:Hemorrhoid 3529:Anal canal 3467:Infectious 3455:Functional 3290:Ulcerative 3174:Duodenitis 3113:Gastrinoma 2761:DiseasesDB 2395:: 167868. 2344:: 464053. 1842:Hepatology 1751:Hepatology 1608:: 203794. 1343:: 895787. 979:2016-01-08 924:2016-01-08 893:2016-01-08 859:References 810:Management 775:Management 749:quinolones 747:, and the 745:vancomycin 723:Management 681:Management 653:Prevention 645:Management 607:furosemide 597:Management 472:L-arginine 384:amiodarone 264:thrombosis 240:prehepatic 4567:Phlebitis 4308:Trans fat 4244:Foam cell 4200:Arteritis 4167:(vessels) 4082:Richter's 4039:Spigelian 4034:Obturator 4024:Umbilical 3857:Ascending 3828:Bile duct 3661:Cirrhosis 3639:Hepatitis 3622:Accessory 3492:Proctitis 3343:Megacolon 3317:Dysentery 3227:Whipple's 3179:Jejunitis 3169:Enteritis 3056:Dyspepsia 3017:Gastritis 2950:Achalasia 2883:Esophagus 2790:radio/570 2785:eMedicine 2081:225058522 1827:2673-4389 845:vena cava 821:Treatment 737:rifaximin 729:lactulose 717:glutamine 507:Diagnosis 376:vitamin A 292:Cirrhosis 120:Cirrhosis 100:, with a 84:Treatment 45:Specialty 4781:Embolism 4383:Aneurysm 4320:Stenosis 4254:Atheroma 4205:Aortitis 4174:Arteries 4012:Indirect 4007:Inguinal 3741:Pyogenic 3686:Vascular 3462:Diarrhea 3440:Volvulus 3406:Vascular 3345: / 3334: / 3295:Ischemic 3262:Appendix 3152:Duodenum 3022:Atrophic 2896:Candidal 2793:med/1889 2689:24829658 2633:22504334 2604:26034348 2551:26804426 2522:27326313 2477:28083082 2421:22888442 2370:23509634 2292:16429901 2251:36120195 2200:35068798 2151:35721838 2073:33097308 2022:35757384 1973:22468079 1919:29249128 1870:23580034 1781:30642150 1773:23463403 1732:16682712 1683:31041029 1634:23024865 1583:26169079 1534:19858596 1475:31316760 1423:Medscape 1404:22504334 1369:22666604 1318:34337369 1240:45193610 1232:25230084 1197:19845427 1189:27251734 1154:29675644 1111:35814519 1055:11 March 1032:30087517 949:11 March 741:neomycin 621:(TIPS). 151:variceal 57:Symptoms 4602:abdomen 4283:Hyaline 4053:Petit's 4029:Femoral 3932:Chronic 3746:Amoebic 3514:Anismus 3280:Colitis 3207:Coeliac 3184:Ileitis 3156:Jejunum 3009:Stomach 2913:Rupture 2815:Scholia 2755:D006975 2680:3990125 2595:4445090 2559:7149809 2513:4909428 2468:5192551 2412:3408669 2361:3594950 2283:1351828 2242:9467492 2191:8766707 2142:9201357 2013:9218432 1964:3309905 1910:5875194 1862:2029990 1723:1455434 1674:6490258 1625:3457672 1574:4701371 1466:6605738 1360:3362051 1309:8318926 1146:2563507 1102:9257868 1023:6078702 888:Patient 587:albumin 572:Ascites 566:Ascites 386:, etc.) 371:, etc.) 294:of any 277:and/or 220:CT scan 179:ascites 128:ascites 61:Ascites 4047:Lumbar 4017:Direct 4000:Hiatus 3980:Hernia 3832:Other 3598:Melena 3484:Rectum 2967:(GERD) 2817:has a 2687:  2677:  2650:  2631:  2602:  2592:  2557:  2549:  2520:  2510:  2475:  2465:  2419:  2409:  2368:  2358:  2315:  2290:  2280:  2249:  2239:  2219:Cureus 2198:  2188:  2149:  2139:  2079:  2071:  2020:  2010:  1971:  1961:  1917:  1907:  1868:  1860:  1825:  1805:Livers 1779:  1771:  1730:  1720:  1681:  1671:  1632:  1622:  1581:  1571:  1532:  1473:  1463:  1402:  1367:  1357:  1316:  1306:  1261:  1238:  1230:  1195:  1187:  1152:  1144:  1126:Lancet 1109:  1099:  1030:  1020:  733:enemas 234:Causes 161:, and 66:Causes 4717:Other 4550:Veins 4400:torso 4342:Other 3972:Other 3927:Acute 3678:MASLD 3631:Liver 3605:Lower 3588:Upper 3430:Ileus 3266:Colon 3160:Ileum 2975:(LPR) 2819:topic 2766:10388 2744:572.3 2729:K76.6 2555:S2CID 2077:S2CID 1866:S2CID 1777:S2CID 1236:S2CID 1193:S2CID 1150:S2CID 296:cause 114:liver 4651:head 4181:and 3360:SCAD 2750:MeSH 2739:9-CM 2685:PMID 2648:ISBN 2629:PMID 2600:PMID 2547:PMID 2518:PMID 2473:PMID 2417:PMID 2393:2012 2366:PMID 2342:2013 2313:ISBN 2288:PMID 2247:PMID 2196:PMID 2147:PMID 2069:PMID 2018:PMID 1969:PMID 1915:PMID 1858:PMID 1823:ISSN 1769:PMID 1728:PMID 1702:CMAJ 1679:PMID 1630:PMID 1606:2012 1579:PMID 1530:PMID 1471:PMID 1400:PMID 1365:PMID 1341:2012 1314:PMID 1269:2013 1259:ISBN 1228:PMID 1185:PMID 1142:PMID 1107:PMID 1057:2021 1028:PMID 951:2021 548:The 541:and 539:left 484:RAAS 106:mmHg 4298:LDL 3666:PBC 3393:IBD 3327:IBS 2735:ICD 2720:ICD 2675:PMC 2621:doi 2590:PMC 2580:doi 2539:doi 2508:PMC 2498:doi 2463:PMC 2453:doi 2407:PMC 2397:doi 2356:PMC 2346:doi 2278:PMC 2237:PMC 2227:doi 2186:PMC 2178:doi 2137:PMC 2129:doi 2059:hdl 2049:doi 2008:PMC 2000:doi 1959:PMC 1949:doi 1905:PMC 1897:doi 1850:doi 1813:doi 1759:doi 1718:PMC 1710:doi 1706:174 1669:PMC 1661:doi 1620:PMC 1610:doi 1569:PMC 1561:doi 1520:doi 1461:PMC 1453:doi 1392:doi 1355:PMC 1345:doi 1304:PMC 1296:doi 1220:doi 1177:doi 1134:doi 1097:PMC 1089:doi 1018:PMC 1010:doi 613:), 492:ADH 488:SNS 224:MRI 222:or 138:or 4926:: 4402:: 4385:/ 4176:, 3830:/ 3428:: 3409:: 3205:: 2788:: 2764:: 2753:: 2742:: 2727:: 2724:10 2683:. 2669:. 2665:. 2627:. 2617:57 2615:. 2598:. 2588:. 2576:21 2574:. 2570:. 2553:. 2545:. 2535:32 2533:. 2516:. 2506:. 2492:. 2488:. 2471:. 2461:. 2447:. 2443:. 2415:. 2405:. 2391:. 2387:. 2364:. 2354:. 2340:. 2336:. 2286:. 2274:32 2272:. 2268:. 2245:. 2235:. 2223:14 2221:. 2217:. 2194:. 2184:. 2174:12 2172:. 2168:. 2145:. 2135:. 2125:15 2123:. 2119:. 2107:^ 2097:. 2075:. 2067:. 2057:. 2045:73 2043:. 2039:. 2016:. 2006:. 1996:15 1994:. 1990:. 1967:. 1957:. 1945:18 1943:. 1939:. 1927:^ 1913:. 1903:. 1893:24 1891:. 1887:. 1864:. 1856:. 1846:13 1844:. 1821:. 1807:. 1803:. 1789:^ 1775:. 1767:. 1755:57 1753:. 1749:. 1726:. 1716:. 1704:. 1700:. 1677:. 1667:. 1655:. 1651:. 1628:. 1618:. 1604:. 1600:. 1577:. 1567:. 1557:35 1555:. 1551:. 1528:. 1516:12 1514:. 1510:. 1483:^ 1469:. 1459:. 1449:13 1447:. 1443:. 1431:^ 1421:. 1398:. 1388:57 1386:. 1363:. 1353:. 1339:. 1335:. 1312:. 1302:. 1290:. 1286:. 1274:^ 1234:. 1226:. 1216:45 1214:. 1191:. 1183:. 1173:41 1171:. 1148:. 1140:. 1105:. 1095:. 1085:12 1083:. 1079:. 1065:^ 1048:. 1026:. 1016:. 1006:35 1004:. 1000:. 988:^ 967:. 942:. 917:. 902:^ 886:. 867:^ 743:, 739:, 731:, 609:, 490:, 486:, 478:. 382:, 298:. 214:) 165:. 157:, 149:, 142:. 130:, 116:. 4579:/ 4389:/ 4157:e 4150:t 4143:v 3866:/ 3539:/ 3358:/ 3354:/ 3268:) 3264:/ 3260:( 3162:) 3158:/ 3154:/ 3150:( 2857:e 2850:t 2843:v 2829:. 2737:- 2722:- 2712:D 2691:. 2671:4 2656:. 2635:. 2623:: 2606:. 2582:: 2561:. 2541:: 2524:. 2500:: 2494:8 2479:. 2455:: 2449:8 2423:. 2399:: 2372:. 2348:: 2321:. 2294:. 2253:. 2229:: 2202:. 2180:: 2153:. 2131:: 2083:. 2061:: 2051:: 2024:. 2002:: 1975:. 1951:: 1921:. 1899:: 1872:. 1852:: 1829:. 1815:: 1809:2 1783:. 1761:: 1734:. 1712:: 1685:. 1663:: 1657:7 1636:. 1612:: 1585:. 1563:: 1536:. 1522:: 1495:. 1477:. 1455:: 1425:. 1406:. 1394:: 1371:. 1347:: 1320:. 1298:: 1292:3 1267:. 1242:. 1222:: 1199:. 1179:: 1156:. 1136:: 1130:1 1113:. 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Index


Specialty
Gastroenterology
Symptoms
Diagnostic method
portal venous pressure
hepatic venous pressure gradient
mmHg
portal vein
liver
Cirrhosis
ascites
vomiting of blood
elevated liver enzymes
low platelet counts
spontaneous bacterial peritonitis
variceal
hepatic encephalopathy
hepatorenal syndrome
cardiomyopathy
ascites
peritoneal cavity
hematemesis
Anorectal varices
splenomegaly
thrombocytopenia
caput medusae
CT scan
MRI
cutoff value

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