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Potassium in biology

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322:(EFSA) refers to the collective set of information as Dietary Reference Values, with Population Reference Intake (PRI) instead of RDA, and Average Requirement instead of EAR. AI and UL are defined the same as in the United States. For people ages 15 and older, the AI is set at 3,500 mg/day. AIs for pregnancy is 3,500 mg/day, for lactation 4,000 mg/day. For children ages 1–14 years, the AIs increase with age from 800 to 2,700 mg/day. These AIs are lower than the U.S. RDAs. The EFSA reviewed the same safety question and decided that there was insufficient data to establish a UL for potassium. 20: 2969: 330:
For U.S. food and dietary supplement labeling purposes, the amount in a serving is expressed as a percent of Daily Value (%DV). For potassium labeling purposes, 100% of the Daily Value was 3500 mg, but as of May 2016, it has been revised to 4700 mg. A table of the old and new adult Daily
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balance. Potassium is necessary for the function of all living cells, and is thus present in all plant and animal tissues. It is found in especially high concentrations within plant cells, and in a mixed diet, it is most highly concentrated in fruits. The high concentration of potassium in plants,
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Gastrointestinal symptoms are the most common side effects of potassium supplements, including nausea, vomiting, abdominal discomfort, and diarrhea. Taking potassium with meals or taking a microencapsulated form of potassium may reduce gastrointestinal side effects.
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National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Food and Nutrition Board; Committee to Review the Dietary Reference Intakes for Sodium and Potassium (March 2019). Oria M, Harrison M, Stallings VA (eds.).
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Dong YY, Pike AC, Mackenzie A, McClenaghan C, Aryal P, Dong L, Quigley A, Grieben M, Goubin S, Mukhopadhyay S, Ruda GF, Clausen MV, Cao L, Brennan PE, Burgess-Brown NA, Sansom MS, Tucker SJ, Carpenter EP (Mar 2015).
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The functions of potassium and sodium in living organisms are quite different. Animals, in particular, employ sodium and potassium differentially to generate electrical potentials in animal cells, especially in
571:. Symptoms of hyperkalemia may include tingling of the hands and feet, muscular weakness, and temporary paralysis. The most serious complication of hyperkalemia is the development of an abnormal heart rhythm ( 315:
revised the Adequate Intake for potassium to 2,600 mg/day for females 19 years of age and older who are not pregnant or lactating, and 3,400 mg/day for males 19 years of age and older.
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Although hyperkalemia is rare in healthy individuals, oral doses greater than 18 grams taken at one time in individuals not accustomed to high intakes can lead to hyperkalemia.
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Pohl, Hanna R.; Wheeler, John S.; Murray, H. Edward (2013). "Chapter 2. Sodium and Potassium in Health and Disease". In Astrid Sigel, Helmut Sigel and Roland K. O. Sigel (ed.).
74:. Potassium depletion in animals, including humans, results in various neurological dysfunctions. Characteristic concentrations of potassium in model organisms are: 30–300mM in 2122: 567:
is the most serious adverse reaction to potassium. Hyperkalemia occurs when potassium builds up faster than the kidneys can remove it. It is most common in individuals with
1986: 2410: 1867: 312: 1960: 770: 3416: 587: 120:. A deficiency of potassium ions can impair a plant's ability to maintain these processes. Potassium also functions in other physiological processes such as 2281: 1863: 521:, or vomiting. Symptoms are related to alterations in membrane potential and cellular metabolism. Symptoms include muscle weakness and cramps, paralytic 2057: 1864:"Sodium and Potassium Dietary Reference Intake Values Updated in New Report; Introduces New Category for Sodium Based on Chronic Disease Risk Reduction" 2366: 548:
Adult women in the United States consume on average half the AI, for men two-thirds. For all adults, fewer than 5% exceed the AI. Similarly, in the
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associated with comparatively very low amounts of sodium there, historically resulted in potassium first being isolated from the ashes of plants (
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Jiang Y, Lee A, Chen J, Cadene M, Chait BT, MacKinnon R (May 2002). "Crystal structure and mechanism of a calcium-gated potassium channel".
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Eating a variety of foods that contain potassium is the best way to get an adequate amount. Foods with high sources of potassium include
2396: 2329: 1954:"Overview on Dietary Reference Values for the EU population as derived by the EFSA Panel on Dietetic Products, Nutrition and Allergies" 216:—a "spike" of electrical discharge. The ability of cells to produce electrical discharge is critical for body functions such as 2114: 1786: 794:"A Hypothesis Relating Critical Potassium Concentrations for Growth to the Distribution and Functions of This Ion in the Plant Cell" 536:
In rare cases, habitual consumption of large amounts of black licorice has resulted in hypokalemia. Licorice contains a compound (
1977: 201: 1595:"Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward rectifier GIRK1 at 1.8 A resolution" 1913: 1804: 1761: 734: 714: 697:
Clausen, Michael Jakob Voldsgaard; Poulsen, Hanne (2013). "Sodium/Potassium Homeostasis in the Cell". In Banci, Lucia (ed.).
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are tetramers with several conserved secondary structural elements. A number of potassium channel structures have been
2156:"Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses" 1953: 1487:
Kuo A, Gulbis JM, Antcliff JF, Rahman T, Lowe ED, Zimmer J, Cuthbertson J, Ashcroft FM, Ezaki T, Doyle DA (Jun 2003).
762: 2004:"Federal Register May 27, 2016 Food Labeling: Revision of the Nutrition and Supplement Facts Labels. FR page 33982" 525:, ECG abnormalities, intestinal paralysis, decreased reflex response and (in severe cases) respiratory paralysis, 351:(2040 mg), mixed with a half-cup (1.12 dL) water, taken two to four times a day, may be used on daily basis. 96:, and as such functions as a regulator of various processes including growth regulation. Plants require potassium 3192: 2278: 189: 3087: 319: 1699:
Mikko Hellgren; Lars Sandberg; Olle Edholm (2006). "A comparison between two prokaryotic potassium channels (K
1440:"Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels" 3365: 2909: 2665: 87: 1546:"Crystal structures of the mammalian GIRK2 K+ channel and gating regulation by G proteins, PIP2, and sodium" 1329:
Miller AN, Long SB (January 2012). "Crystal structure of the human two-pore domain potassium channel K2P1".
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Santoss JS, Asmar-Rovira GA, Han GW, Liu W, Syeda R, Cherezov V, Baker KA, Stevens RC, Montal M (Dec 2012).
308:(ULs) for vitamins and minerals, but for potassium the evidence was insufficient, so no UL was established. 2987: 305: 229: 607: â€“ Ionic solids whose dissociation in water frees up ions carrying the electrical current in solution 3411: 2601: 2563: 92:
The main role of potassium in plants is to provide the ionic environment for metabolic processes in the
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Jiang Y, Lee A, Chen J, et al. (May 2003). "X-ray structure of a voltage-dependent K+ channel".
24: 1849: 2643: 1897: 1644:"Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 A resolution" 848:"Crystal structure of a voltage-gateds K+ channel pore module in a closed state in lipid membranes" 233: 212:. The cell membrane potential created by potassium and sodium ions allows the cell to generate an 2348: 2093: 2638: 2506: 2471: 2003: 749: 741: 236:, including Estimated Average Requirements (EARs) and Recommended Dietary Allowances (RDAs), or 3257: 2904: 2758: 2653: 2596: 2558: 509:
A severe shortage of potassium in body fluids may cause a potentially fatal condition known as
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mg for lactating females that are 19 years of age and older. As for safety, the NAM also sets
3197: 3072: 2698: 2675: 2660: 2591: 2205:"Potassium intake, stroke, and cardiovascular disease a meta-analysis of prospective studies" 185: 1223:"Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel" 3370: 3082: 3042: 3027: 2896: 2753: 2741: 2718: 2648: 2573: 1655: 1500: 1394: 1338: 1285: 1175: 1069: 1014: 963: 910: 616: 133: 1383:"K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac" 8: 3240: 3207: 3167: 3067: 2734: 2729: 2626: 2466: 1274:"Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channel" 1115:"Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel" 628: 501:
Diets low in potassium increase risk of hypertension, stroke and cardiovascular disease.
344: 1737: 1659: 1504: 1398: 1342: 1289: 1179: 1073: 1018: 967: 914: 625: â€“ Electric potential difference between interior and exterior of a biological cell 3431: 3426: 3375: 3334: 3159: 3037: 2530: 2451: 2180: 2155: 1927: 1837: 1818: 1676: 1643: 1624: 1570: 1545: 1526: 1469: 1415: 1382: 1362: 1306: 1273: 1249: 1222: 1198: 1164:"Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel" 1163: 1139: 1114: 1090: 1057: 1038: 987: 936: 874: 847: 815: 810: 793: 622: 598: 368: 169: 165: 1611: 1594: 763:"Cell Biology by the Numbers: What are the concentrations of different ions in cells?" 3344: 3314: 3282: 3277: 3262: 3235: 3182: 3172: 3077: 3057: 3052: 3022: 2836: 2815: 2483: 2478: 2371: 2323: 2261: 2226: 2185: 1931: 1919: 1909: 1822: 1810: 1800: 1767: 1757: 1720: 1681: 1616: 1575: 1518: 1461: 1420: 1366: 1354: 1311: 1254: 1203: 1144: 1095: 1042: 1030: 979: 928: 879: 745: 737: 730: 720: 710: 678: 668: 634: 610: 348: 217: 125: 101: 28: 2388: 1628: 1473: 3309: 3267: 2926: 2583: 2253: 2216: 2175: 2167: 2035: 1901: 1792: 1747: 1712: 1671: 1663: 1606: 1565: 1557: 1530: 1508: 1451: 1410: 1402: 1346: 1301: 1293: 1244: 1234: 1193: 1183: 1134: 1126: 1085: 1077: 1022: 991: 971: 940: 918: 869: 859: 805: 702: 660: 592: 572: 530: 364: 213: 2780: 3380: 3272: 3212: 3177: 3062: 3047: 2973: 2919: 2914: 2285: 2257: 1058:"Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution" 237: 173: 113: 2785: 1891: 706: 664: 371:) containing more than 99 mg (about 1.3 mEq) to be labeled with a warning. 3324: 3319: 3304: 3292: 2827: 2683: 2456: 2446: 2221: 2204: 1561: 1456: 1439: 549: 243:
For both males and females under 9 years of age, the AIs for potassium are: 400
161: 153: 121: 71: 50: 2058:"Potassium Supplement (Oral Route, Parenteral Route) Proper Use - Mayo Clinic" 1716: 1438:
Clarke OB, Caputo AT, Hill AP, Vandenberg JI, Smith BJ, Gulbis JM (Jun 2010).
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mg for pregnant females that are 19 years of age and older; furthermore, 2,500
3405: 3385: 3349: 3339: 3297: 3287: 2870: 2849: 2763: 2688: 2621: 2377: 899:"Crystal structure of a mammalian voltage-dependent Shaker family K+ channel" 568: 177: 54: 43: 3329: 2154:
Aburto NJ, Hanson S, Gutierrez H, Hooper L, Elliott P, Cappuccio FP (2013).
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Stallings, Virginia A; Harrison, Meghan; Oria, Maria, eds. (March 5, 2019).
1667: 1513: 1488: 1406: 1350: 1297: 1188: 1081: 923: 898: 864: 518: 3202: 2875: 2844: 2747: 2436: 2265: 2230: 2189: 1923: 1814: 1771: 1739: 1724: 1685: 1620: 1579: 1522: 1489:"Crysstal structure of the potassium channel KirBac1.1 in the closed state" 1465: 1424: 1358: 1315: 1258: 1207: 1148: 1099: 1034: 983: 932: 883: 724: 682: 564: 537: 467: 384: 78:, 300mM in budding yeast, 100mM in mammalian cell and 4mM in blood plasma. 1221:
Kong C, Zeng W, Ye S, Chen L, Sauer DB, Lam Y, Derebe MG, Jiang Y (2012).
160:(Na) is the major cation outside animal cells. The difference between the 3250: 3187: 2693: 2633: 2568: 2521: 2516: 2511: 2428: 2075: 604: 510: 240:(AIs) for when there is not sufficient information to set EARs and RDAs. 109: 58: 1239: 1130: 975: 19: 3138: 2613: 2553: 2540: 2461: 2420: 2028:"Daily Value Reference of the Dietary Supplement Label Database (DSLD)" 819: 701:. Metal Ions in Life Sciences. Vol. 12. Springer. pp. 41–67. 659:. Metal Ions in Life Sciences. Vol. 13. Springer. pp. 29–47. 205: 2979: 2171: 1698: 277:
For females 9 years of age and older, the AIs for potassium are: 2,300
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For pregnant and lactating females, the AIs for potassium are: 2,600
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For males 9 years of age and older, the AIs for potassium are: 2,500
3222: 3130: 3114: 2865: 2797: 2548: 1905: 1796: 1752: 514: 2202: 1742:. In Stallings, Virginia A; Harrison, Meghan; Oria, Maria (eds.). 300:
mg of potassium for 14 to 18-year-old lactating females, and 2,800
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National Academies of Sciences, Engineering and Medicine (2019).
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Bac1.1 and KcsA) in a molecular dynamics (MD) simulation study".
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Yuan P, Leonetti MD, Pico AR, Hsiung Y, MacKinnon R (July 2010).
513:. Hypokalemia typically results from loss of potassium through 404: 400: 396: 392: 137: 129: 117: 93: 2372:
Oregon State University – Micronutrient Information Center
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Dietary Reference Intakes for Sodium and Potassium – Publication
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dried fruit (apricots, peaches, prunes, raisins; figs and dates)
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mg of potassium for females that are 19 years of age and older.
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Interrelations between Essential Metal Ions and Human Diseases
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mg of potassium for 14 to 18-year-old pregnant females, 2,900
172:. The balance between potassium and sodium is maintained by 136:, and maintenance of cation:anion balance in the cytosol and 105: 1791:. National Academies of Sciences, Engineering and Medicine. 1379: 2153: 1161: 1437: 1271: 2109: 2107: 1868:
National Academies of Sciences, Engineering, and Medicine
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National Academies of Sciences, Engineering, and Medicine
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Mumoli N, Cei M (2008). "Licorice-induced hypokalemia".
2115:"Top 10 Foods Highest in Potassium + One Page Printable" 1979:
Tolerable Upper Intake Levels For Vitamins And Minerals
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Leonetti MD, Yuan P, Hsiung Y, Mackinnon R (Nov 2012).
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mg of potassium for 9 to 18-year-old females, and 2,600
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mg of potassium for 1 to 3-year-old children, and 2,300
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D'Elia L, Barba G, Cappuccio FP, Strazzullo P (2011).
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Brohawn SG, del Mármol J, MacKinnon R (January 2012).
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mg of potassium for 14 to 18-year-old males, and 3,400
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between the inside and outside of cells, known as the
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Brooks/Cole publishers – Sodium Potassium pump
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dark leafy greens (spinach, Swiss chard, and others)
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mg of potassium for 7 to 12-month-old infants, 2,000
1740:"Potassium: Dietary Reference Intakes for Adequacy" 496: 359:Because of the risk of small-bowel lesions, the US 232:(NAM), on behalf of both the U.S. and Canada, sets 132:, phloem solute transport of photoassimilates into 1893:Dietary Reference Intakes for Sodium and Potassium 1744:Dietary Reference Intakes for Sodium and Potassium 1642:Tao X, Avalos JL, Chen J, MacKinnon R (Dec 2009). 1004: 164:of these charged particles causes a difference in 897:Long SB, Campbell EB, Mackinnon R (August 2005). 654: 595: â€“ Neuron communication by electric impulses 540:) that increases urinary excretion of potassium. 274:mg for males that are 19 years of age and older. 266:mg of potassium for 9 to 13-year-old males, 3,000 247:mg of potassium for 0 to 6-month-old infants, 860 3403: 2334:Energy and Nutrient Intake in the European Union 1746:. Washington, DC: The National Academies Press. 1592: 1543: 552:, insufficient potassium intake is widespread. 1220: 791: 696: 259:mg of potassium for 4 to 8-year-old children. 53:, while having a major role in maintenance of 3417:Biology and pharmacology of chemical elements 2995: 2404: 1112: 588:Biology and pharmacology of chemical elements 1692: 953: 555: 457:Foods containing the highest concentration: 2094:"Office of Dietary Supplements - Potassium" 2076:"NCATS Inxight Drugs — POTASSIUM GLUCONATE" 3002: 2988: 2411: 2397: 2349:"Potassium Health Professional Fact Sheet" 1328: 223: 220:, muscle contraction, and heart function. 2243: 2220: 2179: 1751: 1675: 1610: 1569: 1512: 1455: 1414: 1305: 1248: 1238: 1197: 1187: 1138: 1113:Wu Y, Yang Y, Ye S, Jiang Y (July 2010). 1089: 922: 873: 863: 809: 450:nuts (pistachios, almonds, walnuts, etc.) 2279:What We Eat In America, NHANES 2013-2014 2032:Dietary Supplement Label Database (DSLD) 1985:, European Food Safety Authority, 2006, 419:, legumes, and meats contain potassium. 18: 3009: 792:Leigh, R. A.; Wyn Jones, R. G. (1984). 760: 112:to make surrounding guard cells either 3404: 2328:: CS1 maint: archived copy as title ( 1996: 543: 143: 2983: 2392: 619: â€“ Use of Magnesium by organisms 575:), which can lead to cardiac arrest. 422:Common foods very high in potassium: 81: 2016:from the original on August 8, 2016. 1544:Whorton MR, MacKinnon R (Sep 2011). 631: â€“ Use of Selenium by organisms 343:20 mEq (781 mg) potassium from 3100: (Core six elements) 2709:Glycogen phosphorylase isoenzyme BB 1593:Nishida M, MacKinnon R (Dec 2002). 601: â€“ Use of calcium by organisms 104:and for the opening and closing of 13: 2341: 811:10.1111/j.1469-8137.1984.tb04103.x 773:from the original on 20 April 2017 637: â€“ Use of sodium by organisms 613: â€“ Use of Iodine by organisms 453:seeds (squash, pumpkin, sunflower) 14: 3443: 2360: 2353:NIH Office of Dietary Supplements 826: 27:a critical enzyme for regulating 2967: 2125:from the original on 2014-09-11. 1966:from the original on 2017-08-28. 834:Introduction to Plant Physiology 832:Hopkins, W.G. and Huner, N.P.A. 497:High blood pressure/Hypertension 2311:from the original on 2011-07-13 2291: 2272: 2237: 2196: 2147: 2129: 2086: 2068: 2050: 2020: 1992:from the original on 2016-03-16 1970: 1946: 1882: 1856: 1778: 1731: 1635: 1586: 1537: 1480: 1431: 1373: 1322: 1265: 1214: 1155: 1106: 1049: 374: 3088:Biological aspects of fluorine 998: 947: 890: 839: 785: 754: 689: 648: 504: 426:beans (white beans and others) 338: 320:European Food Safety Authority 1: 3366:Composition of the human body 2666:Comprehensive metabolic panel 1612:10.1016/S0092-8674(02)01227-8 641: 491: 354: 306:tolerable upper intake levels 88:Potassium deficiency (plants) 16:Use of Potassium by organisms 2383:Potassium: analyte monograph 2258:10.1016/j.ijcard.2006.11.190 230:National Academy of Medicine 7: 3376:Mineral (Essential element) 2602:Thyroid-stimulating hormone 2564:Total iron-binding capacity 707:10.1007/978-94-007-5561-1_3 665:10.1007/978-94-007-7500-8_2 581: 325: 152:(K, a positive ion) inside 10: 3448: 3391:Uranium in the environment 2943:Elevated alpha-fetoprotein 2222:10.1016/j.jacc.2010.09.070 1562:10.1016/j.cell.2011.07.046 1457:10.1016/j.cell.2010.05.003 85: 3358: 3246:Acute beryllium poisoning 3221: 3158: 3096: 3015: 2935: 2895: 2888: 2858: 2835: 2826: 2796: 2717: 2674: 2612: 2582: 2539: 2492: 2427: 1934:. Bookshelf ID: NBK538102 1717:10.1016/j.bpc.2005.10.002 761:Milo, Ron; Philips, Rob. 556:Side effects and toxicity 234:Dietary Reference Intakes 1898:National Academies Press 1168:Proc Natl Acad Sci U S A 699:Metallomics and the Cell 363:requires some potassium 108:, which is regulated by 2472:BUN-to-creatinine ratio 1668:10.1126/science.1180310 1514:10.1126/science.1085028 1407:10.1126/science.1261512 1351:10.1126/science.1213274 1298:10.1126/science.1213808 1189:10.1073/pnas.1215078109 1082:10.1126/science.1190414 924:10.1126/science.1116269 865:10.1074/jbc.M112.415091 224:Dietary recommendations 148:Potassium is the major 3258:Chlorine gas poisoning 2905:Elevated transaminases 2597:Thyroid function tests 2559:Transferrin saturation 2419:Clinical biochemistry 411:, although many other 333:Reference Daily Intake 331:Values is provided at 182:potassium ion channels 36: 3231:Argyria (Silver) 3073:Molybdenum in biology 2699:Lactate dehydrogenase 2661:Basic metabolic panel 2592:ACTH stimulation test 128:, activation of some 25:Sodium–potassium pump 22: 3371:Lithium (medication) 3083:Arsenic biochemistry 3043:Manganese in biology 3033:Potassium in biology 3028:Magnesium in biology 2719:Liver function tests 2574:Transferrin receptor 2209:J. Am. Coll. Cardiol 617:Magnesium in biology 487:dry roasted soybeans 3241:Beryllium poisoning 3068:Selenium in biology 3010:Elements in biology 2735:Serum total protein 2730:Human serum albumin 1660:2009Sci...326.1668T 1505:2003Sci...300.1922K 1399:2015Sci...347.1256D 1343:2012Sci...335..432M 1290:2012Sci...335..436B 1240:10.7554/eLife.00184 1180:2012PNAS..10919274L 1131:10.1038/nature09252 1074:2010Sci...329..182Y 1019:2002Natur.417..515J 976:10.1038/nature01580 968:2003Natur.423...33J 915:2005Sci...309..897L 767:book.bionumbers.org 629:Selenium in biology 544:Insufficient intake 347:(4680 mg), or 345:potassium gluconate 202:inwardly rectifying 144:Function in animals 3412:Biological systems 3335:Thallium poisoning 3038:Calcium in biology 2507:Arterial blood gas 2284:2017-02-24 at the 2137:"FoodData Central" 2062:www.mayoclinic.org 623:Membrane potential 599:Calcium in biology 464:sun dried tomatoes 369:potassium chloride 170:membrane potential 166:electric potential 82:Function in plants 37: 3399: 3398: 3345:Toxic heavy metal 3330:Selenium toxicity 3315:Mercury poisoning 3283:Fluoride toxicity 3278:Cadmium poisoning 3263:Chromium toxicity 3236:Arsenic poisoning 3078:Iodine in biology 3058:Copper in biology 3053:Cobalt in biology 3023:Sodium in biology 2955: 2954: 2951: 2950: 2884: 2883: 2837:Blood sugar level 2816:Pancreatic lipase 2654:Total cholesterol 2484:Serum osmolal gap 2479:Plasma osmolality 2172:10.1136/bmj.f1378 1915:978-0-309-48834-1 1866:(Press release). 1806:978-0-309-48834-1 1763:978-0-309-48834-1 1654:(5960): 1668–74. 1284:(6067): 4s36–41. 909:(5736): 897–903. 735:978-94-007-5561-1 716:978-94-007-5560-4 674:978-94-007-7499-5 635:Sodium in biology 611:Iodine in biology 349:potassium citrate 218:neurotransmission 126:protein synthesis 102:protein synthesis 49:for all types of 3439: 3422:Dietary minerals 3310:Lithium toxicity 3268:Cobalt poisoning 3004: 2997: 2990: 2981: 2980: 2972: 2971: 2970: 2963: 2927:Hyperproteinemia 2893: 2892: 2833: 2832: 2413: 2406: 2399: 2390: 2389: 2378:Lab Tests Online 2356: 2335: 2333: 2327: 2319: 2317: 2316: 2310: 2303: 2295: 2289: 2276: 2270: 2269: 2241: 2235: 2234: 2224: 2200: 2194: 2193: 2183: 2151: 2145: 2144: 2141:fdc.nal.usda.gov 2133: 2127: 2126: 2111: 2102: 2101: 2090: 2084: 2083: 2072: 2066: 2065: 2054: 2048: 2047: 2045: 2043: 2034:. 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Cardiol 2242: 2238: 2201: 2197: 2152: 2148: 2135: 2134: 2130: 2113: 2112: 2105: 2092: 2091: 2087: 2074: 2073: 2069: 2056: 2055: 2051: 2041: 2039: 2038:on 7 April 2020 2026: 2025: 2021: 2013: 2006: 2002: 2001: 1997: 1989: 1982: 1976: 1975: 1971: 1963: 1956: 1952: 1951: 1947: 1937: 1935: 1916: 1887: 1883: 1873: 1871: 1862: 1861: 1857: 1845: 1844: 1835: 1834: 1827: 1825: 1807: 1783: 1779: 1764: 1736: 1732: 1702: 1697: 1693: 1640: 1636: 1591: 1587: 1542: 1538: 1485: 1481: 1436: 1432: 1378: 1374: 1337:(6067): 432–6. 1327: 1323: 1270: 1266: 1219: 1215: 1174:(47): 19274–9. 1160: 1156: 1125:(7304): 393–7. 1111: 1107: 1068:(5988): 182–6. 1054: 1050: 1027:10.1038/417515a 1003: 999: 962:(6935): 33–41. 952: 948: 895: 891: 844: 840: 831: 827: 798:New Phytologist 790: 786: 776: 774: 759: 755: 717: 694: 690: 675: 653: 649: 644: 584: 558: 546: 507: 499: 494: 377: 357: 341: 328: 301: 297: 293: 289: 282: 278: 271: 267: 263: 256: 252: 248: 244: 226: 204:channels, from 146: 90: 84: 35:levels in cells 17: 12: 11: 5: 3445: 3435: 3434: 3429: 3424: 3419: 3414: 3397: 3396: 3394: 3393: 3388: 3383: 3378: 3373: 3368: 3362: 3360: 3356: 3355: 3353: 3352: 3347: 3342: 3337: 3332: 3327: 3325:Nickel allergy 3322: 3320:Metal toxicity 3317: 3312: 3307: 3305:Lead poisoning 3302: 3301: 3300: 3293:Iron poisoning 3290: 3285: 3280: 3275: 3270: 3265: 3260: 3255: 3254: 3253: 3248: 3238: 3233: 3227: 3225: 3219: 3218: 3216: 3215: 3210: 3205: 3200: 3195: 3190: 3185: 3180: 3175: 3170: 3164: 3162: 3156: 3155: 3153: 3152: 3144: 3136: 3128: 3120: 3112: 3103: 3101: 3094: 3093: 3091: 3090: 3085: 3080: 3075: 3070: 3065: 3060: 3055: 3050: 3045: 3040: 3035: 3030: 3025: 3019: 3017: 3013: 3012: 3007: 3006: 2999: 2992: 2984: 2977: 2976: 2953: 2952: 2949: 2948: 2946: 2945: 2939: 2937: 2933: 2932: 2930: 2929: 2924: 2923: 2922: 2912: 2907: 2901: 2899: 2890: 2886: 2885: 2882: 2881: 2879: 2878: 2873: 2868: 2862: 2860: 2856: 2855: 2853: 2852: 2847: 2841: 2839: 2830: 2824: 2823: 2821: 2820: 2819: 2818: 2808: 2802: 2800: 2794: 2793: 2791: 2790: 2789: 2788: 2783: 2773: 2768: 2767: 2766: 2761: 2756: 2744: 2739: 2738: 2737: 2732: 2723: 2721: 2715: 2714: 2712: 2711: 2706: 2701: 2696: 2691: 2686: 2684:Cardiac marker 2680: 2678: 2676:Cardiovascular 2672: 2671: 2669: 2668: 2663: 2658: 2657: 2656: 2651: 2646: 2641: 2631: 2630: 2629: 2627:Hemoglobin A1c 2618: 2616: 2610: 2609: 2607: 2606: 2605: 2604: 2594: 2588: 2586: 2580: 2579: 2577: 2576: 2571: 2566: 2561: 2556: 2551: 2545: 2543: 2537: 2536: 2534: 2533: 2528: 2523: 2519: 2514: 2509: 2504: 2498: 2496: 2490: 2489: 2487: 2486: 2481: 2476: 2475: 2474: 2469: 2464: 2457:Renal function 2454: 2449: 2444: 2439: 2433: 2431: 2425: 2424: 2416: 2415: 2408: 2401: 2393: 2387: 2386: 2380: 2374: 2369: 2362: 2361:External links 2359: 2358: 2357: 2343: 2340: 2337: 2336: 2290: 2271: 2236: 2215:(10): 1210–9. 2195: 2146: 2128: 2103: 2098:ods.od.nih.gov 2085: 2080:drugs.ncats.io 2067: 2049: 2019: 1995: 1969: 1945: 1914: 1906:10.17226/25353 1881: 1870:. 5 March 2019 1855: 1846:|website= 1805: 1797:10.17226/25353 1777: 1762: 1753:10.17226/25353 1730: 1700: 1691: 1634: 1585: 1556:(1): 199–208. 1536: 1479: 1450:(6): 1018–29. 1430: 1372: 1321: 1264: 1213: 1154: 1105: 1048: 997: 946: 889: 838: 825: 784: 753: 715: 688: 673: 646: 645: 643: 640: 639: 638: 632: 626: 620: 614: 608: 602: 596: 590: 583: 580: 557: 554: 550:European Union 545: 542: 506: 503: 498: 495: 493: 490: 489: 488: 485: 482: 479: 476: 473: 470: 465: 462: 455: 454: 451: 448: 445: 442: 439: 436: 433: 430: 427: 376: 373: 356: 353: 340: 337: 327: 324: 225: 222: 162:concentrations 145: 142: 122:photosynthesis 83: 80: 72:nervous tissue 15: 9: 6: 4: 3: 2: 3444: 3433: 3430: 3428: 3425: 3423: 3420: 3418: 3415: 3413: 3410: 3409: 3407: 3392: 3389: 3387: 3386:Soil salinity 3384: 3382: 3379: 3377: 3374: 3372: 3369: 3367: 3364: 3363: 3361: 3357: 3351: 3350:Zinc toxicity 3348: 3346: 3343: 3341: 3340:Tin poisoning 3338: 3336: 3333: 3331: 3328: 3326: 3323: 3321: 3318: 3316: 3313: 3311: 3308: 3306: 3303: 3299: 3298:Iron overload 3296: 3295: 3294: 3291: 3289: 3288:Halotolerance 3286: 3284: 3281: 3279: 3276: 3274: 3271: 3269: 3266: 3264: 3261: 3259: 3256: 3252: 3249: 3247: 3244: 3243: 3242: 3239: 3237: 3234: 3232: 3229: 3228: 3226: 3224: 3220: 3214: 3211: 3209: 3206: 3204: 3201: 3199: 3196: 3194: 3191: 3189: 3186: 3184: 3181: 3179: 3176: 3174: 3171: 3169: 3166: 3165: 3163: 3161: 3157: 3151: 3149: 3145: 3143: 3141: 3137: 3135: 3133: 3129: 3127: 3125: 3121: 3119: 3117: 3113: 3111: 3109: 3105: 3104: 3102: 3099: 3095: 3089: 3086: 3084: 3081: 3079: 3076: 3074: 3071: 3069: 3066: 3064: 3061: 3059: 3056: 3054: 3051: 3049: 3046: 3044: 3041: 3039: 3036: 3034: 3031: 3029: 3026: 3024: 3021: 3020: 3018: 3014: 3005: 3000: 2998: 2993: 2991: 2986: 2985: 2982: 2975: 2965: 2964: 2961: 2944: 2941: 2940: 2938: 2934: 2928: 2925: 2921: 2918: 2917: 2916: 2913: 2911: 2908: 2906: 2903: 2902: 2900: 2898: 2894: 2891: 2887: 2877: 2874: 2872: 2871:Hyperuricemia 2869: 2867: 2864: 2863: 2861: 2857: 2851: 2850:Hyperglycemia 2848: 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Chem 1695: 1687: 1683: 1678: 1673: 1669: 1665: 1661: 1657: 1653: 1649: 1645: 1638: 1630: 1626: 1622: 1618: 1613: 1608: 1605:(7): 957–65. 1604: 1600: 1596: 1589: 1581: 1577: 1572: 1567: 1563: 1559: 1555: 1551: 1547: 1540: 1532: 1528: 1524: 1520: 1515: 1510: 1506: 1502: 1498: 1494: 1490: 1483: 1475: 1471: 1467: 1463: 1458: 1453: 1449: 1445: 1441: 1434: 1426: 1422: 1417: 1412: 1408: 1404: 1400: 1396: 1392: 1388: 1384: 1376: 1368: 1364: 1360: 1356: 1352: 1348: 1344: 1340: 1336: 1332: 1325: 1317: 1313: 1308: 1303: 1299: 1295: 1291: 1287: 1283: 1279: 1275: 1268: 1260: 1256: 1251: 1246: 1241: 1236: 1232: 1228: 1224: 1217: 1209: 1205: 1200: 1195: 1190: 1185: 1181: 1177: 1173: 1169: 1165: 1158: 1150: 1146: 1141: 1136: 1132: 1128: 1124: 1120: 1116: 1109: 1101: 1097: 1092: 1087: 1083: 1079: 1075: 1071: 1067: 1063: 1059: 1052: 1044: 1040: 1036: 1032: 1028: 1024: 1020: 1016: 1012: 1008: 1001: 993: 989: 985: 981: 977: 973: 969: 965: 961: 957: 950: 942: 938: 934: 930: 925: 920: 916: 912: 908: 904: 900: 893: 885: 881: 876: 871: 866: 861: 857: 853: 849: 842: 835: 829: 821: 817: 812: 807: 803: 799: 795: 788: 772: 768: 764: 757: 751: 747: 743: 739: 736: 732: 726: 722: 718: 712: 708: 704: 700: 692: 684: 680: 676: 670: 666: 662: 658: 651: 647: 636: 633: 630: 627: 624: 621: 618: 615: 612: 609: 606: 603: 600: 597: 594: 591: 589: 586: 585: 579: 576: 574: 570: 569:renal failure 566: 562: 553: 551: 541: 539: 534: 532: 528: 524: 520: 516: 512: 502: 486: 483: 480: 478:yeast extract 477: 474: 471: 469: 466: 463: 460: 459: 458: 452: 449: 446: 444:fish (salmon) 443: 440: 437: 434: 431: 428: 425: 424: 423: 420: 418: 414: 410: 406: 402: 398: 394: 390: 386: 382: 372: 370: 367:(for example 366: 362: 352: 350: 346: 336: 334: 323: 321: 316: 314: 311:In 2019, the 309: 307: 286: 275: 260: 241: 239: 235: 231: 221: 219: 215: 211: 207: 203: 199: 195: 191: 190:voltage gated 187: 183: 179: 178:cell membrane 175: 171: 167: 163: 159: 155: 151: 141: 139: 135: 134:source organs 131: 127: 123: 119: 115: 111: 107: 103: 99: 95: 89: 79: 77: 73: 67: 65: 60: 56: 52: 48: 45: 44:intracellular 41: 34: 30: 26: 21: 3160:Deficiencies 3147: 3139: 3131: 3123: 3115: 3107: 3032: 2910:Elevated ALP 2876:Hypouricemia 2845:Hypoglycemia 2781:Unconjugated 2746: 2441: 2429:Electrolytes 2352: 2313:. Retrieved 2293: 2274: 2252:(3): e42–4. 2249: 2245: 2239: 2212: 2208: 2198: 2163: 2159: 2149: 2140: 2131: 2118: 2097: 2088: 2079: 2070: 2061: 2052: 2040:. Retrieved 2036:the original 2031: 2022: 1998: 1978: 1972: 1948: 1936:. Retrieved 1892: 1884: 1872:. Retrieved 1858: 1826:. Retrieved 1787: 1780: 1743: 1733: 1708: 1704: 1694: 1651: 1647: 1637: 1602: 1598: 1588: 1553: 1549: 1539: 1496: 1492: 1482: 1447: 1443: 1433: 1390: 1386: 1375: 1334: 1330: 1324: 1281: 1277: 1267: 1230: 1226: 1216: 1171: 1167: 1157: 1122: 1118: 1108: 1065: 1061: 1051: 1010: 1006: 1000: 959: 955: 949: 906: 902: 892: 855: 851: 841: 833: 828: 801: 797: 787: 775:. Retrieved 766: 756: 698: 691: 656: 650: 577: 565:Hyperkalemia 563: 559: 547: 538:Glycyrrhizin 535: 508: 500: 468:cocoa solids 456: 421: 385:orange juice 378: 375:Food sources 358: 342: 329: 317: 310: 287: 276: 261: 242: 227: 194:ligand gated 154:animal cells 147: 110:proton pumps 91: 75: 68: 42:is the main 38: 32: 3251:Berylliosis 2859:Nitrogenous 2694:CPK-MB test 2634:Lipid panel 2569:Transferrin 2517:Bicarbonate 2512:Base excess 2421:blood tests 1938:13 November 852:J Biol Chem 836:4th edition 804:(1): 1–13. 744:electronic- 605:Electrolyte 511:hypokalemia 505:Hypokalemia 472:whey powder 461:dried herbs 339:Supplements 206:prokaryotes 198:tandem-pore 59:electrolyte 3406:Categories 3198:Molybdenum 2786:Conjugated 2614:Metabolism 2554:Serum iron 2541:Iron tests 2462:Creatinine 2315:2007-01-30 2119:myfooddata 1874:29 January 1711:(1): 1–9. 1233:: e00184. 642:References 573:arrhythmia 531:arrhythmia 492:Deficiency 417:vegetables 210:eukaryotes 188:including 86:See also: 3432:Potassium 3427:Nutrition 3193:Manganese 3188:Potassium 3142:hosphorus 2776:Bilirubin 2726:Proteins 2704:Myoglobin 2502:Anion gap 2494:Acid-base 2442:Potassium 2166:: f1378. 1932:104464967 1848:ignored ( 1838:cite book 1823:104464967 1367:206537279 1043:205029269 750:1868-0402 742:1559-0836 527:alkalosis 481:rice bran 381:kiwifruit 228:The U.S. 40:Potassium 33:Potassium 3223:Toxicity 3208:Selenium 3168:Chromium 3016:Elements 2974:Medicine 2889:Proteins 2866:Azotemia 2798:Pancreas 2584:Hormones 2549:Ferritin 2447:Chloride 2324:cite web 2306:Archived 2282:Archived 2266:17320224 2231:21371638 2190:23558164 2123:Archived 2011:Archived 1987:archived 1961:Archived 1959:. 2017. 1924:30844154 1815:30844154 1772:30844154 1725:16253415 1686:20019282 1629:15788511 1621:12507423 1580:21962516 1523:12738871 1474:14484301 1466:20564790 1425:25766236 1359:22282804 1316:22282805 1259:23240087 1208:23129643 1149:20574420 1100:20508092 1035:12037559 984:12721618 933:16002581 884:23095758 777:23 March 771:Archived 725:23595670 683:24470088 582:See also 519:diuresis 515:diarrhea 484:molasses 432:potatoes 405:parsnips 401:apricots 397:avocados 389:potatoes 355:Labeling 326:Labeling 156:, while 100:(K) for 3359:Related 3134:itrogen 3118:ydrogen 2806:Amylase 2531:Lactate 2526:content 2452:Calcium 2181:4816263 1828:May 13, 1677:2819303 1656:Bibcode 1648:Science 1571:3243363 1531:2703162 1501:Bibcode 1493:Science 1416:6034649 1395:Bibcode 1387:Science 1339:Bibcode 1331:Science 1307:3329120 1286:Bibcode 1278:Science 1250:3510474 1199:3511096 1176:Bibcode 1140:2910425 1091:3022345 1070:Bibcode 1062:Science 1015:Bibcode 992:4347957 964:Bibcode 941:6072007 911:Bibcode 903:Science 875:3522301 820:2434189 475:paprika 447:avocado 409:turnips 393:coconut 176:in the 138:vacuole 130:enzymes 118:flaccid 106:stomata 94:cytosol 76:E. coli 3203:Sodium 3183:Iodine 3173:Copper 3098:CHONPS 2960:Portal 2811:Lipase 2437:Sodium 2264:  2229:  2188:  2178:  2042:16 May 1930:  1922:  1912:  1821:  1813:  1803:  1770:  1760:  1723:  1684:  1674:  1627:  1619:  1578:  1568:  1529:  1521:  1472:  1464:  1423:  1413:  1365:  1357:  1314:  1304:  1257:  1247:  1206:  1196:  1147:  1137:  1119:Nature 1098:  1088:  1041:  1033:  1007:Nature 990:  982:  956:Nature 939:  931:  882:  872:  818:  748:  740:  733:  723:  713:  681:  671:  441:yogurt 438:squash 413:fruits 302:  298:  294:  290:  283:  279:  272:  268:  264:  257:  253:  249:  245:  200:, and 186:solved 180:. All 158:sodium 150:cation 114:turgid 64:potash 29:Sodium 3150:ulfur 3126:xygen 3110:arbon 2936:Other 2309:(PDF) 2302:(PDF) 2014:(PDF) 2007:(PDF) 1990:(PDF) 1983:(PDF) 1964:(PDF) 1957:(PDF) 1928:S2CID 1819:S2CID 1625:S2CID 1527:S2CID 1470:S2CID 1363:S2CID 1227:eLife 1039:S2CID 988:S2CID 937:S2CID 816:JSTOR 523:ileus 365:salts 55:fluid 51:cells 3213:Zinc 3178:Iron 2467:Urea 2330:link 2262:PMID 2227:PMID 2186:PMID 2044:2020 1940:2022 1920:PMID 1910:ISBN 1876:2022 1850:help 1830:2019 1811:PMID 1801:ISBN 1768:PMID 1758:ISBN 1721:PMID 1682:PMID 1617:PMID 1599:Cell 1576:PMID 1550:Cell 1519:PMID 1462:PMID 1444:Cell 1421:PMID 1355:PMID 1312:PMID 1255:PMID 1204:PMID 1145:PMID 1096:PMID 1031:PMID 980:PMID 929:PMID 880:PMID 779:2017 746:ISSN 738:ISSN 731:ISBN 721:PMID 711:ISBN 679:PMID 669:ISBN 529:and 407:and 318:The 208:and 98:ions 57:and 31:and 23:The 2897:LFT 2771:GGT 2759:AST 2754:ALT 2742:ALP 2644:HDL 2639:LDL 2254:doi 2250:124 2217:doi 2176:PMC 2168:doi 2164:346 2160:BMJ 1902:doi 1793:doi 1748:doi 1713:doi 1709:120 1672:PMC 1664:doi 1652:326 1607:doi 1603:111 1566:PMC 1558:doi 1554:147 1509:doi 1497:300 1452:doi 1448:141 1411:PMC 1403:doi 1391:347 1347:doi 1335:335 1302:PMC 1294:doi 1282:335 1245:PMC 1235:doi 1194:PMC 1184:doi 1172:109 1135:PMC 1127:doi 1123:466 1086:PMC 1078:doi 1066:329 1023:doi 1011:417 972:doi 960:423 919:doi 907:309 870:PMC 860:doi 856:287 806:doi 703:doi 661:doi 361:FDA 116:or 47:ion 3408:: 2522:CO 2351:. 2326:}} 2322:{{ 2304:. 2260:. 2248:. 2225:. 2213:57 2211:. 2207:. 2184:. 2174:. 2162:. 2158:. 2139:. 2121:. 2117:. 2106:^ 2096:. 2078:. 2060:. 2030:. 2009:. 1926:. 1918:. 1908:. 1900:. 1896:. 1842:: 1840:}} 1836:{{ 1817:. 1809:. 1799:. 1766:. 1756:. 1719:. 1707:. 1701:ir 1680:. 1670:. 1662:. 1650:. 1646:. 1623:. 1615:. 1601:. 1597:. 1574:. 1564:. 1552:. 1548:. 1525:. 1517:. 1507:. 1495:. 1491:. 1468:. 1460:. 1446:. 1442:. 1419:. 1409:. 1401:. 1389:. 1385:. 1361:. 1353:. 1345:. 1333:. 1310:. 1300:. 1292:. 1280:. 1276:. 1253:. 1243:. 1229:. 1225:. 1202:. 1192:. 1182:. 1170:. 1166:. 1143:. 1133:. 1121:. 1117:. 1094:. 1084:. 1076:. 1064:. 1060:. 1037:. 1029:. 1021:. 1009:. 986:. 978:. 970:. 958:. 935:. 927:. 917:. 905:. 901:. 878:. 868:. 854:. 850:. 814:. 802:97 800:. 796:. 769:. 765:. 719:. 709:. 677:. 667:. 533:. 517:, 415:, 403:, 399:, 395:, 391:, 387:, 383:, 335:. 196:, 192:, 140:. 124:, 3148:S 3140:P 3132:N 3124:O 3116:H 3108:C 3003:e 2996:t 2989:v 2962:: 2524:2 2412:e 2405:t 2398:v 2332:) 2318:. 2288:. 2268:. 2256:: 2233:. 2219:: 2192:. 2170:: 2143:. 2100:. 2082:. 2064:. 2046:. 1942:. 1904:: 1878:. 1852:) 1832:. 1795:: 1774:. 1750:: 1727:. 1715:: 1688:. 1666:: 1658:: 1631:. 1609:: 1582:. 1560:: 1533:. 1511:: 1503:: 1476:. 1454:: 1427:. 1405:: 1397:: 1369:. 1349:: 1341:: 1318:. 1296:: 1288:: 1261:. 1237:: 1231:1 1210:. 1186:: 1178:: 1151:. 1129:: 1102:. 1080:: 1072:: 1045:. 1025:: 1017:: 994:. 974:: 966:: 943:. 921:: 913:: 886:. 862:: 822:. 808:: 781:. 727:. 705:: 695:* 685:. 663::

Index


Sodium–potassium pump
Sodium
Potassium
intracellular
ion
cells
fluid
electrolyte
potash
nervous tissue
Potassium deficiency (plants)
cytosol
ions
protein synthesis
stomata
proton pumps
turgid
flaccid
photosynthesis
protein synthesis
enzymes
source organs
vacuole
cation
animal cells
sodium
concentrations
electric potential
membrane potential

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