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in patients in whom that particular protein is deficient or absent. There have been significant advances in this treatment. PRT is being tested in clinical trials with the diseases
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191:"Topical application of recombinant type VII collagen incorporates into the dermal-epidermal junction and promotes wound closure"
189:
Wang X, Ghasri P, Amir M, Hwang B, Hou Y, Khalili M, Khilili M, Lin A, Keene D, Uitto J, Woodley DT, Chen M (July 2013).
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75:"Protein replacement therapies for rare diseases: a breeze for regulatory approval?"
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116:"Regulatory watch: enhanced chance of success for protein replacement therapies"
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165:"Protein Replacement Therapy Shows Promise in Treating Rare Skin Disorder"
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National
Institute of Arthritis and Musculoskeletal and Skin Diseases
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171:. U.S. Department of Health and Human Services
35:as a potential treatment. For patients with
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73:Gorzelany JA, de Souza MP (March 2013).
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39:there have been promising results.
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244:"Protein Therapy vs. Gene Therapy"
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37:epidermolysis bullosa dystrophica
33:epidermolysis bullosa dystrophica
23:that supplements or replaces a
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120:Nature Reviews. Drug Discovery
79:Science Translational Medicine
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242:Stegmann TJ (December 2006).
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17:Protein replacement therapy
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49:Enzyme replacement therapy
114:Crunkhorn S (June 2013).
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195:Molecular Therapy
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60:References
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43:See also
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