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Radiofrequency ablation

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596:. The balloon-based radiofrequency procedure was invented by Robert A. Ganz, Roger Stern and Brian Zelickson in 1999 (System and Method for Treating Abnormal Tissue in the Human Esophagus). While the person is sedated, a catheter is inserted into the esophagus and radiofrequency energy is delivered to the diseased tissue. This outpatient procedure typically lasts from fifteen to thirty minutes. Two months after the procedure, the physician performs an upper endoscopic examination to assess the esophagus for residual Barrett's esophagus. If any Barrett's esophagus is found, the disease can be treated with a focal RFA device. Between 80 and 90% or greater of people in numerous clinical trials have shown complete eradication of Barrett's esophagus in approximately two to three treatments with a favorable safety profile. The treatment of Barrett's esophagus by RFA is durable for up to 5 years. 352:
meditation. Inhibition of the neural impulses that are believed to cause or worsen hypertension has been tried for a few decades. Surgical sympathectomy has helped but not without significant side effects. Therefore, the introduction of non-surgical means of renal denervation using a radiofrequency ablation catheter was enthusiastically welcomed. Although the initial use of radiofrequency-generated heat to ablate nerve endings in the renal arteries to aid in management of 'resistant hypertension' were encouraging, the most recent phase 3 studying looking at catheter-based renal denervation for the treatment of resistant hypertension failed to show any significant reduction in systolic blood pressure.
243:. Since the procedure was first introduced for the treatment of osteoid osteomas in the 1990s, it has been shown in numerous studies to be less invasive and expensive, to result in less bone destruction and to have equivalent safety and efficacy to surgical techniques, with 66 to 95% of people reporting freedom from symptoms. While initial success rates with RFA are high, symptom recurrence after RFA treatment has been reported, with some studies demonstrating a recurrence rate similar to that of surgical treatment. RFA is also increasingly used in the palliative treatment of painful 274: 31: 333:
using a coolant which flows through the catheter) which avoids the risk of complete heart block – a potential complication of radiofrequency ablation in this condition. Recurrence rates with cryoablation are higher, though. Microwave ablation, where tissue is ablated by the microwave energy "cooking" the adjacent tissue, and ultrasonic ablation, creating a heating effect by mechanical vibration, or laser ablation have also been developed but are not in widespread use.
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RFA is a minimally invasive procedure which can usually be done in day-surgery clinics, going home shortly after completion of the procedure. The person is awake during the procedure, so risks associated with general anesthesia are avoided. Whether for back or knee pain, a drawback for this procedure
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RFA may be performed to treat tumors in the lung, liver, kidney, and bone, as well as other body organs less commonly. Once the diagnosis of tumor is confirmed, a needle-like RFA probe is placed inside the tumor. The radiofrequency waves passing through the probe increase the temperature within tumor
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The possibility of skin burn during the procedure is very small, because the large volumes (500 cc) of dilute Lidocaine (0.1%) tumescent anesthesia injected along the entire vein prior to the application of radiofrequency provide a heat sink that absorbs the heat created by the device. Early studies
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Ablation is now the standard treatment for SVT and typical atrial flutter, In some conditions, especially forms of intra-nodal re-entry (the most common type of SVT), also called atrioventricular nodal reentrant tachycardia or AVNRT, ablation can also be accomplished by cryoablation (tissue freezing
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using the heat energy of radio frequency waves to ablate the fibroid tissue. The Acessa device obtained FDA approval in 2012. The device is inserted via a laparoscopic probe and guided inside the fibroid tissue using an ultrasound probe. The heat shrinks the fibroids. Clinical data on the procedure
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knees indicated that ultrasound-guided bony landmarks could be used to effectively target the superior medial geniculate nerve, superior lateral geniculate nerve, and inferior medial geniculate nerve – the three nerves commonly targeted for knee RFA – with average nerve-to-needle distances of 1.7,
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ablation is a dermatosurgical procedure by using various forms of alternating current. Types of radiofrequency are electrosection, electrocoagulation, electrodessication and fulguration. The use of radiofrequency ablation has obtained importance as it can be used to treat most of the skin lesions
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Radiofrequency ablation has been used successfully on benign thyroid nodules for decades, most notably in Europe, South America and Korea. In the United States, the FDA approved the use of RFA techniques for thyroid nodules in 2018. Since then, professional guidelines reflect its use as a viable
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that avoids collateral damage, which is crucial in the head and neck region due to its high density of major nerves and blood vessels. RFA also does not require high temperatures. However, overheating from misapplication of RFA can cause harmful effects such as coagulation on the surface of the
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is a very common condition, with about 1 billion people over the world, nearly 75 million in the US alone. Complications of inadequately controlled hypertension are many and have both individual and global impact. Treatment options include medications, diet, exercise, weight reduction and
329:. Radiofrequency ablation for AF can be unipolar (one electrode) or bipolar (two electrodes). Although bipolar can be more successful, it is technically more difficult, resulting in unipolar being used more often. But bipolar is more effective in preventing recurrent atrial arrhythmias. 231:
RFA can usually be administered as an outpatient procedure, though may at times require a brief hospital stay. RFA may be combined with locally delivered chemotherapy to treat hepatocellular carcinoma (primary liver cancer). A method currently in phase III trials uses the low-level heat
376:. It is an alternative to the traditional stripping operation. Under ultrasound guidance, a radiofrequency catheter is inserted into the abnormal vein and the vessel treated with radio-energy, resulting in closure of the involved vein. Radiofrequency ablation is used to treat the 2654:
Jasim S, Patel KN, Randolph G, et al. (April 2022). "American Association of Clinical Endocrinology Disease State Clinical Review: The Clinical Utility of Minimally Invasive Interventional Procedures in the Management of Benign and Malignant Thyroid Lesions".
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Weber MA, Sprengel SD, Omlor GW, et al. (April 25, 2015). "Clinical long-term outcome, technical success, and cost analysis of radiofrequency ablation for the treatment of osteoblastomas and spinal osteoid osteomas in comparison to open surgical resection".
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published an update in Endocrine Practice, stating that the "new image-guided minimally invasive approaches appear safe and effective alternatives when used appropriately and by trained professionals to treat symptomatic or enlarging thyroid masses".
573:). Other sources indicate 4-5 genicular nerve targets may be justified for ablation to optimize pain relief, while a 2022 analysis indicated that as many as 10 genicular nerve targets for RFA would produce better long-term relief of knee pain. 2561:
Van Vilsteren FG, Pouw RE, Seewald S, et al. (June 2011). "Stepwise radical endoscopic resection versus radiofrequency ablation for Barrett's oesophagus with high grade dysplasia or early cancer: a multicentre randomised trial".
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RFA is also used in radiofrequency lesioning for vein closure in areas where intrusive surgery is contraindicated by trauma, and in liver resection to control bleeding (hemostasis) and facilitate the transection process.
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issued the position statement "Thyroid ablative procedures provide valid alternative treatment strategies to conventional surgical management for a subset of patients with symptomatic benign thyroid nodules.
388:. The latter are connecting veins that transport blood from the superficial veins to the deep veins. Branch varicose veins are then usually treated with other minimally invasive procedures, such as 277:
Schematic view of a pulmonary vein ablation. The catheter reaches (from below) through the inferior vena cava, the right atrium and the left atrium, to the orifice of the left upper pulmonary vein.
1583:"Cryoablation Versus Radiofrequency Energy for the Ablation of Atrioventricular Nodal Reentrant Tachycardia (the CYRANO Study) : Results From a Large Multicenter Prospective Randomized Trial" 532:. Genicular nerve block is a short (10-30 minutes), outpatient procedure usually performed weeks before genicular RFA. The extent of pain reduction by injecting a local anesthetic, such as 232:(hyperthermia) created by the RFA probe to trigger release of concentrated chemotherapeutic drugs from heat-sensitive liposomes in the margins around the ablated tissue as a treatment for 502:
injections provide temporary pain relief, the injection is repeated a second time to confirm the diagnosis. Then RFA is performed on the nerve(s) that responded well to the injections.
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The procedure is similar to a thyroid biopsy, although instead of using a needle to remove cells from the nodule, a probe delivers heat to the interior of the nodule that effectively
547:) to each target genicular nerve, then the radiofrequency electrode is passed through the cannula, and the electrode tip is heated to about 80 °C (176 °F) for one minute to 536:, at specific locations of the target genicular nerves, is self-assessed by the person for hours after the procedure, leading to confirmation with the physician of the need for RFA. 172:
current (over previously used low frequency AC or pulses of DC) are that it does not directly stimulate nerves or heart muscle, and therefore can often be used without the need for
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in multiple gestation pregnancies. This has an acceptable success rate for saving the 'pump' twin in recent studies compared to previous methods including laser photocoagulation.
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Fleischer DE, Overholt BF, Sharma VK, et al. (2010). "Endoscopic radiofrequency ablation for Barrett's esophagus: 5-year outcomes from a prospective multicenter trial".
565:. As of 2023, reviews of clinical outcomes indicated that efficacy for reducing knee pain was achieved by ablating three or more branches of the genicular nerve (one of the 1072: 576:
Knee pain relief of 50% or more following genicular RFA may last from several months to two years, and can be repeated by the same outpatient procedure when pain recurs.
950: 2336:"Can ultrasound-guided radiofrequency ablation of genicular nerves of the knee, be performed without locating corresponding arterial pulsations – a cadaveric study" 224:
tissue, which results in destruction of the tumor. RFA can be used with small tumors, whether these arose within the organ (primary tumors) or spread to the organ (
176:, and that it is specific for treating the desired tissue without significant collateral damage. Due to this, RFA is an alternative for eligible patients who have 2607:"General Principles for the Safe Performance, Training, and Adoption of Ablation Techniques for Benign Thyroid Nodules: An American Thyroid Association Statement" 2203: 1047: 2768:
Chuter GS, Chua YP, Connell DA, et al. (January 2013). "Ultrasound-guided radiofrequency ablation in the management of interdigital (Morton's) neuroma".
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Rosenthal DI, Alexander A, Rosenberg AE, et al. (April 1, 1992). "Ablation of osteoid osteomas with a percutaneously placed electrode: a new procedure".
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Documented benefits have led to RFA becoming widely used during the 21st century. RFA procedures are performed under image guidance (such as X-ray screening,
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As of 2019, several hundred publications showed promise for substantial, long-term (6 months or longer) reduction of knee pain following genicular RFA.
309:. The energy-emitting probe (electrode) is at the tip of a catheter which is placed into the heart, usually through a vein. This catheter is called the 644:
In order to qualify for an RFA procedure, a person must have a clearly benign thyroid nodule, usually proven by two fine needle aspiration biopsies.
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Rimondi E, Mavrogenis AF, Rossi G, et al. (August 14, 2011). "Radiofrequency ablation for non-spinal osteoid osteomas in 557 patients".
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Rosenthal DI, Hornicek FJ, Torriani M, et al. (October 1, 2003). "Osteoid Osteoma: Percutaneous Treatment with Radiofrequency Energy".
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a small segment of the nerve. The heat destroys that segment of the nerve, which is prevented from sending pain signals to the brain.
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Ganz R, Utley D, Stern R, et al. (2004). "Complete Ablation of Esophageal Epithelium Using a Balloon-based Bipolar Electrode".
400:. Currently, the VNUS ClosureRFS stylet is the only device specifically cleared by FDA for endovenous ablation of perforator veins. 641:
the tissue. Over the course of 3-6 months, the nodule will continue to shrink, typically achieving a 50-80% reduction total size.
2155:"Indications of the Neurotomy of Genicular Nerves by Radiofrequency for the Treatment of Knee Osteoarthritis: A Literature Review" 2088:"Genicular Nerve Radiofrequency Ablation for the Treatment of Painful Knee Osteoarthritis: Current Evidence and Future Directions" 528:, is clinically preceded by confirming pain reduction upon anesthetizing the main knee sensory nerves in a test procedure called 281:
Radiofrequency energy is used in heart tissue or normal parts to destroy abnormal electrical pathways that are contributing to a
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is that nerves recover function over time, so the pain relief achieved lasts only temporarily (3–15 months) in most people.
491:. By generating heat around the nerve, the nerve is ablated, thus destroying its ability to transmit signals to the brain. 844: 445:. Unlike other electrosurgical devices, RFA allows very specific treatment targeting of the desired tissue with a precise 438: 413: 1812:"Management of Obstructive Sleep Apnea in Adults: A Clinical Practice Guideline From the American College of Physicians" 317:) before the responsible tissue is eliminated. Radiofrequency ablation technique can be used in AF, either to block the 3526: 3202: 3107: 2271: 3655: 3407: 1785: 561:
had approved in 2017 a commercial device using cooled RFA, with effects lasting for up to a year of pain relief from
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Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC)
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In the procedure for genicular RFA, a guide cannula is first directed under local anesthesia and imaging (
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Gurdezi S, White T, Ramesh P (2013). "Alcohol injection for Morton's neuroma: a five-year follow-up".
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is reviewed in that main article, including controversies and potential advantages in selected
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A new indication for the use of radiofrequency technology has made news in the last few years.
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electrode, boiling within tissue that can leave "a gaping hole", tears, or even charring.
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The nerves to be ablated are identified through injections of local anesthesia (such as
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RFA has become increasingly important in the care of benign bone tumors, most notably
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Sabiston textbook of surgery : the biological basis of modern surgical practice
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treatment modality for thyroid nodules, and the procedure is increasingly applied.
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Radiofrequency ablation is a minimally invasive procedure used in the treatment of
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in people who are not eligible or do not respond to traditional therapies ( i.e.
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Radiofrequency ablation has been shown to be a safe and effective treatment for
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Daily Telegraph – June 2008 – Lung cancer radiation treatment offers new hope
918: 909: 812: 638: 548: 393: 127: 2575: 2320: 2034:"Genicular Nerve Ablation Review Using Cooled-Radiofrequency Nerve Ablation" 1869: 135: 3380: 2832: 2789: 2725: 2676: 2640: 2583: 2547: 2490: 2441: 2433: 2406: 2371: 2297: 2253: 2188: 2170: 2111: 2067: 2049: 1988: 1929: 1888: 1837: 1760: 1708: 1649: 1608: 1567: 1518: 1464: 1322: 1279: 1228: 1141: 1033: 936: 830: 570: 483:
are used to produce heat on specifically identified nerves surrounding the
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where the outcome appears to be more reliable than alcohol injections.
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after implantation of a pacemaker or to block conduction within the
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Radiofrequency ablation of sensory nerves in the knee, also called
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Ariel de Lima D, Gonçalves MC, Grando ST, et al. (May 2019).
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Qaseem A, Holty, JE, Owens, DK, et al. (September 24, 2013).
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Rosenthal DI, Hornicek FJ, Wolfe MW, et al. (June 1, 1998).
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have shown a high success rate with low rates of complications.
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Hadjicostas P, Malakounides N, Varianos C, et al. (2006).
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thyroid nodules, although research into this topic is ongoing.
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Bashetty K, Gururaj Nadig Sandhya Kapoor (November 19, 2009).
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Dupuy DE, Liu D, Hartfeil D, et al. (February 15, 2010).
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Kolakkanni C, Gonnade NM, Gaur R, et al. (August 2023).
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BBC News- 16 January 2009 – Liver tumours 'microwaved away'
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1945:"A History of the Development of Radiofrequency Neurotomy" 1790:
American Academy of Otolaryngology – Head and Neck Surgery
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CT scan showing radiofrequency ablation of a liver lesion
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As of 2020, RFA is not recommended for the treatment of
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Shaheen NJ, Sharma P, Overholt BF, et al. (2009).
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Kidd VD, Strum SR, Strum DS, et al. (March 2019).
2757:. San Jose, CA: The Mercury News, Digital First Media. 2604: 2313:"How I Do It: Genicular Nerve Radiofrequency Ablation" 2032:
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Obstructive sleep apnea § Radiofrequency ablation
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Ambrogi MC, Fanucchi O, Cioni R, et al. (2011).
742: 2690:Rangel LG, Steck JH, Volpi EM, et al. (2022). 422:(OSA) in a pig model. RFA has been recognized as a 199:, a gastrointestinal or surgical endoscopist, or a 2810: 794: 1786:"Submucosal Ablation of the Tongue Base for OSAS" 623:American Association of Clinical Endocrinologists 3647: 2310: 1904:"Temperature Controlled Radiofrequency Ablation" 1733:Avery J, Kumar K, Thakur V, et al. (2014). 1531: 608: 336: 2201: 1476: 1474: 426:treatment option in selected situations by the 2384: 1108:"Radiofrequency ablation in pancreatic cancer" 983:Dunn, Lauren, Gussone, Felix (June 13, 2017). 118:, is a medical procedure in which part of the 2866: 2008:"Radiofrequency ablation for pain management" 1780: 1778: 870:"Radiofrequency Ablation for Pain Management" 724:. National Cancer Institute. February 2, 2011 722:"Fulguration: NCI Dictionary of Cancer Terms" 364:with minimal side effects and complications. 2227: 1525: 1480: 1471: 430:but was not endorsed for general use in the 2752: 2908:Cardiology diagnostic tests and procedures 2873: 2859: 2223: 2221: 2027: 2025: 1775: 407: 29: 3004:Transcatheter pulmonary valve replacement 2715: 2630: 2537: 2480: 2361: 2351: 2287: 2270:Gupta A, Huettner DP, Dukewich M (2017). 2178: 2123: 2121: 2081: 2079: 2077: 2057: 2002: 2000: 1998: 1978: 1960: 1919: 1878: 1868: 1827: 1750: 1698: 1688: 1639: 1598: 1557: 1538:Arrhythmia & Electrophysiology Review 1508: 1454: 1361: 1131: 1023: 926: 908: 820: 663:This process has also been used to treat 487:called the lumbar medial branches of the 355: 120:electrical conduction system of the heart 3047:shunt from heart chamber to blood vessel 2598: 2265: 2263: 2148: 2146: 516:Nerve block § Genicular nerve block 272: 214: 3147:shunt from blood vessel to blood vessel 2218: 2022: 1829:10.7326/0003-4819-159-7-201310010-00704 1722:Endovenous ablation of perforator veins 790: 788: 786: 784: 736: 471:to treat chronic pain arising from the 3648: 2683: 2118: 2074: 1995: 1803: 864: 862: 782: 780: 778: 776: 774: 772: 770: 768: 766: 764: 587: 3277:Valve-sparing aortic root replacement 3016:enlargement of existing septal defect 2854: 2647: 2327: 2260: 2143: 1532:Pearman CM, Poon SS, Gupta D (2017). 978: 976: 974: 678:RFA is also used in the treatment of 35:Tissue ablation using radiofrequency. 3011:production of septal defect in heart 2038:Seminars in Interventional Radiology 1901: 965:"Radiofrequency ablation for cancer" 2311:Greco G, Torres J, Kohan L (2022). 953:. American Heart Association. 2017. 859: 837: 761: 180:or do not want to undergo surgery. 13: 3108:transposition of the great vessels 3033:creation of septal defect in heart 2202:Jessup, Cynthia (April 21, 2017). 2131:. Cleveland Clinic. March 17, 2023 2010:. Cleveland Clinic. March 14, 2022 971: 872:. Cleveland Clinic. March 14, 2022 801:JBJS Essential Surgical Techniques 675:show an average of 45% shrinkage. 599: 453: 428:American Academy of Otolaryngology 14: 3682: 3408:Cardiac resynchronization therapy 2753:King, Paula (December 10, 2012). 1857:Journal of Conservative Dentistry 1600:10.1161/circulationaha.110.970350 1501:10.2174/1573403X14666180524100608 489:dorsal ramus of the spinal nerves 367: 3632: 3631: 2315:. ASRA Pain Medicine News, #47. 1372:10.2106/00004623-199806000-00005 897:Journal of the Endocrine Society 3415:Left atrial appendage occlusion 2804: 2761: 2746: 2732: 2554: 2505: 2469:New England Journal of Medicine 2456: 2413: 2378: 2304: 2195: 2159:Revista Brasileira De Ortopedia 1936: 1895: 1844: 1726: 1715: 1664: 1615: 1574: 1414: 1337: 1286: 1243: 1191: 1169:10.1148/radiology.183.1.1549690 1148: 1099: 1088: 1077: 1066: 1040: 999: 584:3.2, and 1.8 mm, respectively. 957: 943: 884: 714: 439:RFA in obstructive sleep apnea 432:American College of Physicians 161:, it is called radiofrequency 138:using the heat generated from 1: 3537:Radionuclide ventriculography 2399:10.1016/s0016-5107(04)02220-5 2340:BMC Musculoskeletal Disorders 1677:Clin Cosmet Investig Dermatol 743:Courtney M. Townsend (2012). 707: 654: 609:Timeline in the United States 343:Renal sympathetic denervation 337:Renal sympathetic denervation 303:Multifocal Atrial Tachycardia 262: 3522:Myocardial perfusion imaging 2530:10.1053/j.gastro.2011.04.061 2228:Tran A, Gonzalez FM (2023). 1908:Indian Pacing Electrophysiol 1025:10.1097/JTO.0b013e31822d538d 847:. Mayo Clinic. April 6, 2024 632: 615:American Thyroid Association 559:Food and Drug Administration 437:The clinical application of 295:supraventricular tachycardia 7: 2669:10.1016/j.eprac.2022.02.011 1816:Annals of Internal Medicine 1481:Soucek F, Starek Z (2018). 685: 259:or analgesic medications). 201:cardiac electrophysiologist 157:. When it is delivered via 10: 3687: 3129:for univentricular defect 2708:10.1016/j.aace.2022.02.005 2696:AACE Clinical Case Reports 2387:Gastrointestinal Endoscopy 2353:10.1186/s12891-023-06761-8 2246:10.1007/s00256-022-04058-w 1752:10.1177/000313481408000316 1488:Current Cardiology Reviews 951:"Ablation for Arrhythmias" 845:"Radiofrequency neurotomy" 513: 411: 340: 285:. It is used in recurrent 266: 193:interventional radiologist 3629: 3608: 3580: 3469:Implantable loop recorder 3437: 3292: 3188: 3113:Arterial switch operation 2928: 2921: 2903:Interventional cardiology 2893: 2782:10.1007/s00256-012-1527-x 2740:"Acessa Health Procedure" 1307:10.1007/s00330-011-2240-1 1264:10.1148/radiol.2291021053 1213:10.1007/s00256-015-2139-z 1124:10.1080/13651820500466673 418:RFA was first studied in 210: 94: 80: 52: 40: 28: 23: 3656:Interventional radiology 3548:Coronary catheterization 3038:Blalock–Hanlon procedure 2999:Mitral valve replacement 2982:Aortic valve replacement 2825:10.1177/1071100713489555 1949:Journal of Pain Research 1902:Eick OJ (July 1, 2002). 813:10.2106/JBJS.ST.18.00016 692:Interventional radiology 509: 325:, especially around the 305:(MAT) and some types of 234:hepatocellular carcinoma 149:setting, using either a 47:Interventional radiology 16:Interventional procedure 3544:Cardiac catheterization 3486:Electrophysiology study 3386:Radiofrequency ablation 3351:Alcohol septal ablation 2576:10.1136/gut.2010.229310 2321:10.52211/asra020122.006 2129:"Genicular nerve block" 1870:10.4103/0972-0707.58332 579:An anatomical study of 458: 420:obstructive sleep apnea 408:Obstructive sleep apnea 315:electrophysiology study 245:metastatic bone disease 108:Radiofrequency ablation 24:Radiofrequency ablation 3590:Impedance cardiography 3212:Coronary artery bypass 2434:10.1055/s-0030-1255779 2171:10.1055/s-0039-1692121 2050:10.1055/s-0042-1745797 1550:10.15420/aer/2017.29.2 910:10.1210/jendso/bvab110 390:ambulatory phlebectomy 356:Aesthetics dermatology 307:ventricular arrhythmia 278: 255:, palliative surgery, 220: 3621:Transcutaneous pacing 3425:Heart transplantation 3346:Ventricular reduction 3162:Blalock–Taussig shunt 2623:10.1089/thy.2023.0281 2482:10.1056/NEJMoa0808145 2289:10.36076/ppj.2017.171 1641:10.1056/NEJMoa1402670 670:RFA is used to treat 530:genicular nerve block 319:atrioventricular node 276: 218: 3595:Ballistocardiography 3152:systemic circulation 2098:(Suppl 1): S20–S23. 1350:J Bone Joint Surg Am 987:. NBC News, New York 967:. Mayo Clinic. 2017. 481:Radiofrequency waves 382:small saphenous vein 378:great saphenous vein 203:, a subspecialty of 3671:Medical terminology 3661:Vascular procedures 3474:Cardiac stress test 3452:Electrocardiography 3391:Pacemaker insertion 3138:Kawashima procedure 3102:compound procedures 2977:Aortic valve repair 2950:Mitral valve repair 1962:10.2147/JPR.S334862 1690:10.2147/CCID.S50367 594:Barrett's esophagus 588:Barrett's esophagus 522:genicular neurotomy 467:, was developed by 447:line of demarcation 291:atrial fibrillation 155:twilight anesthesia 143:alternating current 130:or a dysfunctional 3527:Cardiovascular MRI 3457:Vectorcardiography 3312:Pericardial window 3307:Pericardiocentesis 3248:Drug-eluting stent 3077:Rastelli procedure 3026:Balloon septostomy 2657:Endocrine Practice 2234:Skeletal Radiology 2104:10.1093/pm/pnab129 1439:10.1002/cncr.24837 1402:on October 6, 2016 1295:European Radiology 1201:Skeletal Radiology 443:medical situations 398:foam sclerotherapy 299:atrial tachycardia 283:cardiac arrhythmia 279: 221: 174:general anesthesia 168:Two advantages of 3666:Surgical oncology 3643: 3642: 3500:Angiocardiography 3446:Electrophysiology 3433: 3432: 3376:Catheter ablation 3359:Conduction system 3284:LeCompte maneuver 3272:Bentall procedure 3133:Norwood procedure 3123:Senning procedure 3118:Mustard procedure 3021:Atrial septostomy 2972:Valve replacement 2617:(10): 1150–1170. 754:978-1-4377-1560-6 269:Catheter ablation 249:radiation therapy 197:otolaryngologists 163:catheter ablation 105: 104: 3678: 3635: 3634: 3600:Cardiotocography 3568: 3532:Ventriculography 3505:Echocardiography 3496: 3448: 3364:Maze procedure ( 3361: 3327: 3303: 3256: 3255:Obstacle removal 3243:Bare-metal stent 3239: 3199: 3156:pulmonary artery 3148: 3103: 3088:pulmonary artery 3061:Fontan procedure 3056:pulmonary artery 3048: 3012: 2926: 2925: 2875: 2868: 2861: 2852: 2851: 2845: 2844: 2808: 2802: 2801: 2765: 2759: 2758: 2750: 2744: 2743: 2736: 2730: 2729: 2719: 2687: 2681: 2680: 2651: 2645: 2644: 2634: 2602: 2596: 2595: 2558: 2552: 2551: 2541: 2518:Gastroenterology 2509: 2503: 2502: 2484: 2460: 2454: 2453: 2417: 2411: 2410: 2382: 2376: 2375: 2365: 2355: 2331: 2325: 2324: 2308: 2302: 2301: 2291: 2267: 2258: 2257: 2225: 2216: 2215: 2213: 2211: 2199: 2193: 2192: 2182: 2150: 2141: 2140: 2138: 2136: 2125: 2116: 2115: 2083: 2072: 2071: 2061: 2029: 2020: 2019: 2017: 2015: 2004: 1993: 1992: 1982: 1964: 1940: 1934: 1933: 1923: 1899: 1893: 1892: 1882: 1872: 1848: 1842: 1841: 1831: 1807: 1801: 1800: 1798: 1796: 1782: 1773: 1772: 1754: 1730: 1724: 1719: 1713: 1712: 1702: 1692: 1668: 1662: 1661: 1643: 1634:(15): 1393–401. 1619: 1613: 1612: 1602: 1578: 1572: 1571: 1561: 1529: 1523: 1522: 1512: 1478: 1469: 1468: 1458: 1418: 1412: 1411: 1409: 1407: 1398:. Archived from 1365: 1363:10.1.1.1018.5024 1341: 1335: 1334: 1290: 1284: 1283: 1247: 1241: 1240: 1195: 1189: 1188: 1152: 1146: 1145: 1135: 1103: 1097: 1092: 1086: 1081: 1075: 1070: 1064: 1063: 1061: 1059: 1050:. Archived from 1044: 1038: 1037: 1027: 1003: 997: 996: 994: 992: 980: 969: 968: 961: 955: 954: 947: 941: 940: 930: 912: 888: 882: 881: 879: 877: 866: 857: 856: 854: 852: 841: 835: 834: 824: 792: 759: 758: 740: 734: 733: 731: 729: 718: 702:Heart arrhythmia 680:Morton's neuroma 672:uterine fibroids 569:branches of the 500:local anesthesia 386:perforator veins 241:osteoid osteomas 151:local anesthetic 140:medium frequency 98:edit on Wikidata 90: 33: 21: 20: 3686: 3685: 3681: 3680: 3679: 3677: 3676: 3675: 3646: 3645: 3644: 3639: 3625: 3604: 3576: 3572:Phonocardiogram 3564: 3494:Cardiac imaging 3492: 3444: 3429: 3357: 3341:Septal myectomy 3331:Cardiomyoplasty 3323: 3317:Pericardiectomy 3299: 3288: 3254: 3235: 3195: 3189:Cardiac vessels 3184: 3178:Glenn procedure 3146: 3101: 3084:right ventricle 3046: 3010: 2932: 2917: 2913:Cardiac imaging 2898:Cardiac surgery 2889: 2879: 2849: 2848: 2809: 2805: 2770:Skeletal Radiol 2766: 2762: 2751: 2747: 2738: 2737: 2733: 2688: 2684: 2652: 2648: 2603: 2599: 2559: 2555: 2510: 2506: 2475:(22): 2277–88. 2461: 2457: 2418: 2414: 2383: 2379: 2332: 2328: 2309: 2305: 2268: 2261: 2226: 2219: 2209: 2207: 2200: 2196: 2151: 2144: 2134: 2132: 2127: 2126: 2119: 2084: 2075: 2030: 2023: 2013: 2011: 2006: 2005: 1996: 1941: 1937: 1900: 1896: 1849: 1845: 1808: 1804: 1794: 1792: 1784: 1783: 1776: 1731: 1727: 1720: 1716: 1669: 1665: 1620: 1616: 1593:(22): 2239–45. 1579: 1575: 1530: 1526: 1479: 1472: 1419: 1415: 1405: 1403: 1342: 1338: 1291: 1287: 1248: 1244: 1196: 1192: 1153: 1149: 1104: 1100: 1093: 1089: 1082: 1078: 1071: 1067: 1057: 1055: 1054:on June 7, 2016 1046: 1045: 1041: 1018:(12): 2044–51. 1004: 1000: 990: 988: 981: 972: 963: 962: 958: 949: 948: 944: 889: 885: 875: 873: 868: 867: 860: 850: 848: 843: 842: 838: 793: 762: 755: 741: 737: 727: 725: 720: 719: 715: 710: 697:Radio frequency 688: 657: 635: 611: 602: 600:Thyroid nodules 590: 518: 512: 461: 456: 454:Pain management 416: 410: 370: 358: 345: 339: 327:pulmonary veins 271: 265: 257:bisphosphonates 213: 170:radio frequency 114:), also called 101: 86: 36: 17: 12: 11: 5: 3684: 3674: 3673: 3668: 3663: 3658: 3641: 3640: 3630: 3627: 3626: 3624: 3623: 3618: 3612: 3610: 3606: 3605: 3603: 3602: 3597: 3592: 3586: 3584: 3582:Function tests 3578: 3577: 3575: 3574: 3569: 3561: 3560: 3555: 3550: 3541: 3540: 3539: 3529: 3524: 3519: 3518: 3517: 3512: 3502: 3497: 3489: 3488: 3483: 3482: 3481: 3479:Bruce protocol 3471: 3466: 3464:Holter monitor 3461: 3460: 3459: 3449: 3441: 3439: 3435: 3434: 3431: 3430: 3428: 3427: 3422: 3417: 3411: 3410: 3405: 3399: 3393: 3388: 3383: 3378: 3373: 3362: 3354: 3353: 3348: 3343: 3338: 3333: 3328: 3320: 3319: 3314: 3309: 3304: 3296: 3294: 3290: 3289: 3287: 3286: 3280: 3279: 3274: 3268: 3267: 3262: 3260:Endarterectomy 3257: 3251: 3250: 3245: 3240: 3237:Coronary stent 3232: 3231: 3230: 3229: 3224: 3219: 3205: 3200: 3192: 3190: 3186: 3185: 3183: 3182: 3181: 3180: 3166: 3165: 3164: 3149: 3143: 3142: 3141: 3140: 3135: 3127: 3126: 3125: 3120: 3115: 3104: 3098: 3097: 3096: 3095: 3081: 3080: 3079: 3068:left ventricle 3065: 3064: 3063: 3049: 3043: 3042: 3041: 3040: 3030: 3029: 3028: 3023: 3013: 3007: 3006: 3001: 2996: 2995: 2994: 2989: 2987:Ross procedure 2979: 2974: 2969: 2968: 2967: 2962: 2952: 2947: 2942: 2936: 2934: 2923: 2919: 2918: 2916: 2915: 2910: 2905: 2900: 2894: 2891: 2890: 2885:involving the 2878: 2877: 2870: 2863: 2855: 2847: 2846: 2819:(8): 1064–67. 2813:Foot Ankle Int 2803: 2760: 2745: 2731: 2682: 2663:(4): 433–448. 2646: 2597: 2553: 2504: 2455: 2428:(10): 781–89. 2412: 2393:(6): 1002–10. 2377: 2326: 2303: 2282:(3): 155–171. 2276:Pain Physician 2259: 2240:(5): 941–949. 2217: 2194: 2165:(3): 233–240. 2142: 2117: 2073: 2044:(2): 130–137. 2021: 1994: 1935: 1894: 1843: 1802: 1774: 1725: 1714: 1663: 1614: 1573: 1544:(4): 202–209. 1524: 1495:(3): 185–191. 1470: 1413: 1336: 1285: 1242: 1190: 1147: 1098: 1087: 1076: 1065: 1039: 1012:J Thorac Oncol 998: 970: 956: 942: 903:(8): bvab110. 883: 858: 836: 760: 753: 735: 712: 711: 709: 706: 705: 704: 699: 694: 687: 684: 656: 653: 634: 631: 610: 607: 601: 598: 589: 586: 563:knee arthritis 511: 508: 475:in the lower ( 469:Nikolai Bogduk 460: 457: 455: 452: 412:Main article: 409: 406: 374:varicose veins 369: 368:Varicose veins 366: 361:Radiofrequency 357: 354: 338: 335: 287:atrial flutter 264: 261: 212: 209: 128:sensory nerves 103: 102: 95: 92: 91: 84: 78: 77: 56: 50: 49: 44: 38: 37: 34: 26: 25: 15: 9: 6: 4: 3: 2: 3683: 3672: 3669: 3667: 3664: 3662: 3659: 3657: 3654: 3653: 3651: 3638: 3628: 3622: 3619: 3617: 3616:Cardioversion 3614: 3613: 3611: 3607: 3601: 3598: 3596: 3593: 3591: 3588: 3587: 3585: 3583: 3579: 3573: 3570: 3567: 3563: 3562: 3559: 3556: 3554: 3551: 3549: 3545: 3542: 3538: 3535: 3534: 3533: 3530: 3528: 3525: 3523: 3520: 3516: 3513: 3511: 3508: 3507: 3506: 3503: 3501: 3498: 3495: 3491: 3490: 3487: 3484: 3480: 3477: 3476: 3475: 3472: 3470: 3467: 3465: 3462: 3458: 3455: 3454: 3453: 3450: 3447: 3443: 3442: 3440: 3436: 3426: 3423: 3421: 3418: 3416: 3413: 3412: 3409: 3406: 3403: 3400: 3397: 3394: 3392: 3389: 3387: 3384: 3382: 3379: 3377: 3374: 3371: 3367: 3363: 3360: 3356: 3355: 3352: 3349: 3347: 3344: 3342: 3339: 3337: 3336:Dor procedure 3334: 3332: 3329: 3326: 3322: 3321: 3318: 3315: 3313: 3310: 3308: 3305: 3302: 3298: 3297: 3295: 3291: 3285: 3282: 3281: 3278: 3275: 3273: 3270: 3269: 3266: 3263: 3261: 3258: 3253: 3252: 3249: 3246: 3244: 3241: 3238: 3234: 3233: 3228: 3225: 3223: 3220: 3218: 3215: 3214: 3213: 3209: 3206: 3204: 3201: 3198: 3194: 3193: 3191: 3187: 3179: 3176: 3175: 3174: 3171:to the right 3170: 3167: 3163: 3160: 3159: 3157: 3153: 3150: 3145: 3144: 3139: 3136: 3134: 3131: 3130: 3128: 3124: 3121: 3119: 3116: 3114: 3111: 3110: 3109: 3105: 3100: 3099: 3094: 3091: 3090: 3089: 3085: 3082: 3078: 3075: 3074: 3073: 3069: 3066: 3062: 3059: 3058: 3057: 3053: 3050: 3045: 3044: 3039: 3036: 3035: 3034: 3031: 3027: 3024: 3022: 3019: 3018: 3017: 3014: 3009: 3008: 3005: 3002: 3000: 2997: 2993: 2992:Transcatheter 2990: 2988: 2985: 2984: 2983: 2980: 2978: 2975: 2973: 2970: 2966: 2963: 2961: 2958: 2957: 2956: 2955:Valvuloplasty 2953: 2951: 2948: 2946: 2943: 2941: 2938: 2937: 2935: 2931: 2927: 2924: 2920: 2914: 2911: 2909: 2906: 2904: 2901: 2899: 2896: 2895: 2892: 2888: 2884: 2876: 2871: 2869: 2864: 2862: 2857: 2856: 2853: 2842: 2838: 2834: 2830: 2826: 2822: 2818: 2814: 2807: 2799: 2795: 2791: 2787: 2783: 2779: 2776:(1): 107–11. 2775: 2771: 2764: 2756: 2749: 2741: 2735: 2727: 2723: 2718: 2713: 2709: 2705: 2702:(2): 99–101. 2701: 2697: 2693: 2686: 2678: 2674: 2670: 2666: 2662: 2658: 2650: 2642: 2638: 2633: 2628: 2624: 2620: 2616: 2612: 2608: 2601: 2593: 2589: 2585: 2581: 2577: 2573: 2570:(6): 765–73. 2569: 2565: 2557: 2549: 2545: 2540: 2535: 2531: 2527: 2524:(2): 460–68. 2523: 2519: 2515: 2508: 2500: 2496: 2492: 2488: 2483: 2478: 2474: 2470: 2466: 2459: 2451: 2447: 2443: 2439: 2435: 2431: 2427: 2423: 2416: 2408: 2404: 2400: 2396: 2392: 2388: 2381: 2373: 2369: 2364: 2359: 2354: 2349: 2345: 2341: 2337: 2330: 2322: 2318: 2314: 2307: 2299: 2295: 2290: 2285: 2281: 2277: 2273: 2266: 2264: 2255: 2251: 2247: 2243: 2239: 2235: 2231: 2224: 2222: 2205: 2198: 2190: 2186: 2181: 2176: 2172: 2168: 2164: 2160: 2156: 2149: 2147: 2135:September 18, 2130: 2124: 2122: 2113: 2109: 2105: 2101: 2097: 2093: 2092:Pain Medicine 2089: 2082: 2080: 2078: 2069: 2065: 2060: 2055: 2051: 2047: 2043: 2039: 2035: 2028: 2026: 2009: 2003: 2001: 1999: 1990: 1986: 1981: 1976: 1972: 1968: 1963: 1958: 1955:: 3897–3907. 1954: 1950: 1946: 1939: 1931: 1927: 1922: 1917: 1913: 1909: 1905: 1898: 1890: 1886: 1881: 1876: 1871: 1866: 1863:(4): 139–44. 1862: 1858: 1854: 1847: 1839: 1835: 1830: 1825: 1822:(7): 471–83. 1821: 1817: 1813: 1806: 1791: 1787: 1781: 1779: 1770: 1766: 1762: 1758: 1753: 1748: 1745:(3): 231–35. 1744: 1740: 1736: 1729: 1723: 1718: 1710: 1706: 1701: 1696: 1691: 1686: 1682: 1678: 1674: 1667: 1659: 1655: 1651: 1647: 1642: 1637: 1633: 1629: 1625: 1618: 1610: 1606: 1601: 1596: 1592: 1588: 1584: 1577: 1569: 1565: 1560: 1555: 1551: 1547: 1543: 1539: 1535: 1528: 1520: 1516: 1511: 1506: 1502: 1498: 1494: 1490: 1489: 1484: 1477: 1475: 1466: 1462: 1457: 1452: 1448: 1444: 1440: 1436: 1433:(4): 989–97. 1432: 1428: 1424: 1417: 1401: 1397: 1393: 1389: 1385: 1381: 1377: 1373: 1369: 1364: 1359: 1356:(6): 815–21. 1355: 1351: 1347: 1340: 1332: 1328: 1324: 1320: 1316: 1312: 1308: 1304: 1301:(1): 181–88. 1300: 1296: 1289: 1281: 1277: 1273: 1269: 1265: 1261: 1258:(1): 171–75. 1257: 1253: 1246: 1238: 1234: 1230: 1226: 1222: 1218: 1214: 1210: 1207:(7): 981–93. 1206: 1202: 1194: 1186: 1182: 1178: 1174: 1170: 1166: 1162: 1158: 1151: 1143: 1139: 1134: 1129: 1125: 1121: 1117: 1113: 1109: 1102: 1096: 1091: 1085: 1080: 1074: 1069: 1053: 1049: 1043: 1035: 1031: 1026: 1021: 1017: 1013: 1009: 1002: 986: 979: 977: 975: 966: 960: 952: 946: 938: 934: 929: 924: 920: 916: 911: 906: 902: 898: 894: 887: 871: 865: 863: 846: 840: 832: 828: 823: 818: 814: 810: 806: 802: 798: 791: 789: 787: 785: 783: 781: 779: 777: 775: 773: 771: 769: 767: 765: 756: 750: 746: 739: 723: 717: 713: 703: 700: 698: 695: 693: 690: 689: 683: 681: 676: 673: 668: 666: 665:TRAP sequence 661: 652: 650: 645: 642: 640: 630: 627: 624: 619: 616: 606: 597: 595: 585: 582: 577: 574: 572: 568: 564: 560: 555: 552: 550: 546: 542: 537: 535: 531: 527: 526:genicular RFA 523: 517: 507: 503: 501: 497: 492: 490: 486: 482: 478: 474: 470: 466: 451: 448: 444: 440: 435: 433: 429: 425: 421: 415: 405: 401: 399: 395: 394:sclerotherapy 391: 387: 383: 379: 375: 365: 362: 353: 350: 344: 334: 330: 328: 324: 320: 316: 312: 308: 304: 300: 296: 292: 288: 284: 275: 270: 260: 258: 254: 250: 246: 242: 237: 235: 229: 227: 217: 208: 206: 205:cardiologists 202: 198: 194: 190: 186: 181: 179: 175: 171: 166: 164: 160: 156: 152: 148: 144: 141: 137: 133: 129: 125: 121: 117: 113: 109: 99: 93: 89: 85: 83: 79: 76: 72: 68: 64: 60: 57: 55: 51: 48: 45: 43: 39: 32: 27: 22: 19: 3404:implantation 3398:implantation 3385: 3381:Cryoablation 3222:Off-pump CAB 3032: 3015: 2940:Valve repair 2930:Heart valves 2816: 2812: 2806: 2773: 2769: 2763: 2748: 2734: 2699: 2695: 2685: 2660: 2656: 2649: 2614: 2610: 2600: 2567: 2563: 2556: 2521: 2517: 2507: 2472: 2468: 2458: 2425: 2421: 2415: 2390: 2386: 2380: 2343: 2339: 2329: 2306: 2279: 2275: 2237: 2233: 2208:. Retrieved 2197: 2162: 2158: 2133:. Retrieved 2095: 2091: 2041: 2037: 2014:September 6, 2012:. Retrieved 1952: 1948: 1938: 1914:(3): 66–73. 1911: 1907: 1897: 1860: 1856: 1846: 1819: 1815: 1805: 1793:. Retrieved 1789: 1742: 1738: 1728: 1717: 1680: 1676: 1666: 1631: 1628:N Engl J Med 1627: 1617: 1590: 1586: 1576: 1541: 1537: 1527: 1492: 1486: 1430: 1426: 1416: 1404:. Retrieved 1400:the original 1353: 1349: 1339: 1298: 1294: 1288: 1255: 1251: 1245: 1204: 1200: 1193: 1163:(1): 29–33. 1160: 1156: 1150: 1118:(1): 61–64. 1115: 1111: 1101: 1090: 1079: 1068: 1056:. Retrieved 1052:the original 1042: 1015: 1011: 1001: 989:. Retrieved 959: 945: 900: 896: 886: 876:September 5, 874:. Retrieved 851:September 5, 849:. Retrieved 839: 804: 800: 744: 738: 726:. Retrieved 716: 677: 669: 662: 658: 646: 643: 636: 628: 621:- 2022: the 620: 613:- 2023: the 612: 603: 591: 578: 575: 571:tibial nerve 556: 553: 538: 529: 525: 521: 519: 504: 493: 485:facet joints 473:facet joints 462: 436: 434:guidelines. 417: 402: 371: 359: 349:Hypertension 346: 331: 310: 280: 253:chemotherapy 238: 230: 222: 182: 167: 115: 111: 107: 106: 18: 3558:Cardiac PET 3301:Pericardium 3265:Atherectomy 3203:Angioplasty 2945:Valvulotomy 1795:October 29, 1587:Circulation 639:cauterizess 545:fluoroscopy 534:bupivacaine 424:somnoplasty 323:left atrium 178:comorbities 116:fulguration 3650:Categories 3553:Cardiac CT 3420:Cardiotomy 3325:Myocardium 3093:Sano shunt 2883:procedures 2881:Tests and 2346:(1): 654. 2206:. FDA News 1683:: 231–41. 807:(1): e10. 708:References 655:Other uses 541:ultrasound 514:See also: 384:, and the 341:See also: 267:See also: 263:Cardiology 226:metastases 189:ultrasound 147:outpatient 2933:and septa 2422:Endoscopy 1971:1178-7090 1447:1097-0142 1406:August 7, 1380:0021-9355 1358:CiteSeerX 1315:0938-7994 1272:0033-8419 1252:Radiology 1221:0364-2348 1177:0033-8419 1157:Radiology 919:2472-1972 649:malignant 633:Procedure 567:articular 549:cauterize 496:lidocaine 465:rhizotomy 42:Specialty 3637:Category 3370:minimaze 3366:Cox maze 2833:23669161 2798:25166343 2790:23073898 2726:35415224 2677:35396078 2641:37642289 2632:10611977 2592:53530205 2584:21209124 2548:21679712 2499:22864452 2491:19474425 2450:24224546 2442:20857372 2407:15605025 2372:37587439 2363:10429091 2298:28339430 2254:35462577 2210:June 13, 2189:31363275 2112:34308957 2068:35781999 1989:34992451 1930:17006561 1889:20543922 1838:24061345 1769:23552772 1761:24666862 1709:25210469 1650:24678939 1609:21098435 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Index


Specialty
Interventional radiology
ICD-9-CM
01.32
04.2
37.33
37.34
60.97
MeSH
D017115
edit on Wikidata
electrical conduction system of the heart
tumor
sensory nerves
tissue
ablated
medium frequency
alternating current
outpatient
local anesthetic
twilight anesthesia
catheter
catheter ablation
radio frequency
general anesthesia
comorbities
CT scan
ultrasound
interventional radiologist

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