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Research ethics

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965:. International codes of conduct and national legislation on research integrity have officially endorsed open sharing of scientific output (publications, data, and code used to perform statistical analyses on the data) as ways to limit questionable research practices and to enhance reproducibility. Having both the data and the actual code enables others to reproduce the results for themselves (or to uncover problems in the analyses when trying to do so). The European Code of Conduct for Research Integrity 2023 states, for example, the principles that, "Researchers, research institutions, and organisations ensure that access to data is as open as possible, as closed as necessary, and where appropriate in line with the FAIR Principles (Findable, Accessible, Interoperable and Reusable) for data management" and that "Researchers, research institutions, and organisations are transparent about how to access and gain permission to use data, 216: 1155:. Such tenets may allow doctors, care providers, and families to create a treatment plan and work towards the same common goal. These four values are not ranked in order of importance or relevance and they all encompass values pertaining to medical ethics. However, a conflict may arise leading to the need for hierarchy in an ethical system, such that some moral elements overrule others with the purpose of applying the best moral judgement to a difficult medical situation. Medical ethics is particularly relevant in decisions regarding 80: 1389: 821: 987: 1080:, indicate some form of scientific misconduct. However the ORI will only investigate allegations of impropriety where research was funded by federal grants. They routinely monitor such research publications for red flags and their investigation is subject to a statute of limitations. Other private organizations like the Committee of Medical Journal Editors (COJE) can only police their own members. 22: 957:
The concrete impact of codes of conduct and other measures put in place to ensure research integrity remain uncertain. Several case studies have highlighted that while the principles of typical codes of conduct adhere to common scientific ideals, they are seen as remote from actual work practices and
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Medical ethics encompasses beneficence, autonomy, and justice as they relate to conflicts such as euthanasia, patient confidentiality, informed consent, and conflicts of interest in healthcare. In addition, medical ethics and culture are interconnected as different cultures implement ethical values
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now available, but a limited number of dialysis machines to treat patients, an ethical question arose on which patients to treat and which ones not to treat, and which factors to use in making such a decision. More recently, new techniques for gene editing aiming at treating, preventing and curing
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Scientific literature on research integrity falls mostly into two categories: first, mapping of the definitions and categories, especially in regard to scientific misconduct, and second, empirical surveys of the attitudes and practices of scientists. Following the development of codes of conduct,
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As this field continues to develop and change throughout history, the focus remains on fair, balanced, and moral thinking across all cultural and religious backgrounds around the world. The field of medical ethics encompasses both practical application in clinical settings and scholarly work in
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The consequences of scientific misconduct can be damaging for perpetrators and journal audience and for any individual who exposes it. In addition there are public health implications attached to the promotion of medical or other interventions based on false or fabricated research findings.
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metadata, protocols, code, software, and other research materials". References to open science have incidentally opened up the debate over scientific integrity beyond academic communities, as it increasingly concerns a wider audience of scientific
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for clinical research. Researchers refer to populations with limited autonomy as "vulnerable populations"; these are subjects who may not be able to fairly decide for themselves whether to participate. Examples of vulnerable populations include
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taxonomies of non-ethical uses have been significantly expanded, beyond the long-established forms of scientific fraud (plagiarism, falsification and fabrication of results). Definitions of "questionable research practices" and the debate over
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Swedish definition: "Intention distortion of the research process by fabrication of data, text, hypothesis, or methods from another researcher's manuscript form or publication; or distortion of the research process in other
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or any other condition which precludes their autonomy, and to a lesser extent, any population for which there is reason to believe that the research study could seem particularly or unfairly persuasive or misleading.
1252:, and technologies. It proposes the discussion about moral discernment in society (what decisions are "good" or "bad" and why) and it is often related to medical policy and practice, but also to broader questions as 1996:
Nylenna, M.; Andersen, D.; Dahlquist, G.; Sarvas, M.; Aakvaag, A. (1999). "Handling of scientific dishonesty in the Nordic countries. National Committees on Scientific Dishonesty in the Nordic Countries".
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led to heightened debate on the ethical norms of sciences and the limitations of the self-regulation processes implemented by scientific communities and institutions. Formalized definitions of
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In Canada, there are different committees for different agencies. The committees are the Research Ethics Board (REB) as well as two others that split their committee duties between conduct (
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and related scientific research. Medical ethics is based on a set of values that professionals can refer to in the case of any confusion or conflict. These values include the respect for
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diseases utilizing gene editing, are raising important moral questions about their applications in medicine and treatments as well as societal impacts on future generations.
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to the treatment of human and animal subjects. The societal responsibilities that science and research have are not traditionally included and are less well defined.
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developed out of centuries of general malpractice and science motivated only by results. Medical ethics in turn led to today's more broad understanding in
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Danish definition: "Intention or gross negligence leading to fabrication of the scientific message or a false credit or emphasis given to a scientist"
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Do not translate text that appears unreliable or low-quality. If possible, verify the text with references provided in the foreign-language article.
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Study participants are entitled to some degree of autonomy in deciding their participation. One measure for safeguarding this right is the use of
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differently, sometimes placing more emphasis on family values and downplaying the importance of autonomy. This leads to an increasing need for
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for research integrity are widespread. Along with codes of conduct at institutional and national levels, major international texts include the
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In Canada, mandatory research ethics training is required for students, professors and others who work in research. The US first legislated
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which led to international codes of research ethics. No approach has been universally accepted, but typically-cited codes are the 1947
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Shaw SE, Petchey RP, Chapman J, Abbott S (2009). "A double-edged sword? Health research and research governance in UK primary care."
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Wickson, Fern; Preston, Christopher; Binimelis, Rosa; Herrero, Amaranta; Hartley, Sarah; Wynberg, Rachel; Wynne, Brian (2017-06-09).
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Content in this edit is translated from the existing Portuguese Knowledge article at ]; see its history for attribution.
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Morreim, E H; Winer, Jeffrey C (2023). "Guest authorship as research misconduct: definitions and possible solutions".
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also target a grey area of dubious scientific results, which may not be the outcome of voluntary manipulations.
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It is 10 years, to the month, since Stephen Lock ... Reproduced with kind permission of the Editor, The Lancet.
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discusses basic principles for medical professionals. This document dates back to the fifth century BCE. Both
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Güldal D, Semin S (2000). "The influences of drug companies' advertising programs on physicians".
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Consequences for the environment, for society and for future generations must be considered.
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Butler, Catherine R.; Mehrotra, Rajnish; Tonelli, Mark R.; Lam, Daniel Y. (2016-04-07).
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are carried out in an ethical manner in accordance with national and international law.
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Appel, JM. Must My Doctor Tell My Partner? Rethinking Confidentiality In the HIV Era,
2010: 1367:, children, prisoners, soldiers, people under detention, migrants, persons exhibiting 3343: 3203: 3180: 3175: 3075: 3068: 3041: 2973: 2931: 2863: 2822: 2773: 2714: 2679: 2617: 2585: 2508: 2490: 2451: 2410: 2329: 2270: 2223: 2198: 2154:"Consequences of Whistleblowing for the Whistleblower in Misconduct in Science Cases" 2139: 2127: 2014: 1926: 1897: 1885: 1832: 1797: 1756: 1744: 1700: 1646: 1634: 1614: 1347: 1341: 1319: 1021: 672: 580: 565: 523: 506: 441: 426: 242: 237: 199: 156: 2726: 2341: 2026: 1516:
several authors suggested that research ethics in a medical context is dominated by
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related to health (primarily focused on the human, but also increasingly includes
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Research Ethics and Integrity for Social Scientists: Beyond Regulatory Compliance
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provides the following sample definitions, reproduced in The COPE report 1999:
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physicians and ethical committees in hospitals and other healthcare settings.
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After 2010, debates on research integrity have been increasingly linked to
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includes many large scale violations and crimes against humanity such as
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includes many large scale violations and crimes against humanity such as
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Clinical trials : what patients and healthy volunteers need to know
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Veit, Walter (2018). "Procreative Beneficence and Genetic Enhancement".
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Ethical problems particularly encumber using children in clinical trials
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The Story of Bioethics: From seminal works to contemporary explorations
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to the source of your translation. A model attribution edit summary is
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Stahl, Bernd Carsten; Timmermans, Job; Flick, Catherine (2016-09-19).
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Three percent of the 3,475 research institutions that report to the
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Secretariat on Responsible Conduct of Research (5 February 2016).
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is both a field of study and professional practice, interested in
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Brow, Julie A. (June 2002). "When culture and medicine collide".
1245: 1202: 1152: 1025: 1013: 2430:"The Code of Medical Ethics of the American Medical Association" 121: 2746:
World Journal of Gastrointestinal Pharmacology and Therapeutics
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Proceedings of the 2013 Australasian Ethics Network Conference
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The European Union only sets the guidelines for its member's
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Handling of Scientific Misconduct in Scandinavian countries
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A reconstruction of the skull purportedly belonging to the
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Mohamadi, Amin; Asghari, Fariba; Rashidian, Arash (2014).
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Beauchamp, J. (2013). "Principles of Biomedical Ethics".
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have rights which they expect to be honored, including:
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and, in modern times, from the much more broad field of
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to this template: there are already 473 articles in the
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Introduction of Research Methods and Publication Ethics
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are the areas that raise ethical questions most often.
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a machine-translated version of the Portuguese article.
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Clinical Journal of the American Society of Nephrology
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The Southwest Respiratory and Critical Care Chronicles
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Singh, Dr. Yatendra Kumar; Kumar Dubey, Bipin (2021).
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which led to international codes of research ethics.
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Ethics and the Scholarship of Teaching and Learning
2156:. Research Triangle Institute. 1995. Archived from 1952: 3067: 2742:"Are medical ethics universal or culture specific" 2733: 2690: 2628: 2598: 2286: 1664: 2846:Journal of Medical Ethics and History of Medicine 2641: 2570: 2519: 2377: 2348: 2243:Part III. Department of Health and Human Services 1972:"European Code of Conduct for Research Integrity" 3335: 2312:Weise, Mary (2016). "Medical Ethics Made Easy". 2215: 911:is an aspect of research ethics that deals with 3139: 3090:The Oxford Textbook of Clinical Research Ethics 2582:A Cross-Cultural Dialogue on Health Care Ethics 2527:"Safeguarding the future of human gene editing" 2269:, Treasure Island (FL): StatPearls Publishing, 35:for grammar, style, cohesion, tone, or spelling 2913: 1296:"), ethical education in science, animal, and 994:, a long-lasting case of scientific misconduct 159:accompanying your translation by providing an 104:Click for important translation instructions. 91:expand this article with text translated from 3125: 1665:Israel, Mark; Allen, G.; Thomson, C. (2013). 1244:), including those emerging from advances in 1084: 690: 2180: 1817:"Ethical Decision-Making in Social Research" 1066:Scientific misconduct can result in loss of 2696: 2260: 1914:Ethics in Engineering Practice and Research 1488:Large international organizations like the 1309: 1304: 3132: 3118: 2914:Stockley, Denise; Wright, Madison (2022), 2901:"Panel on Responsible Conduct of Research" 2888:. Government of Canada. 28 September 2004. 2647: 2102: 1074:US Department of Health and Human Services 1001:is the violation of the standard codes of 697: 683: 214: 3035: 2857: 2816: 2767: 2757: 2665: 2502: 2445: 2404: 2356:"Bioethic Tools: Principles of Bioethics" 2292: 1879: 1791: 1353: 59:Learn how and when to remove this message 2964:, Informa Healthcare, pp. 876–882, 1910: 1718: 1716: 1439:is a body responsible for ensuring that 1135:which analyzes the practice of clinical 985: 972: 922:First introduced in the 19th century by 628:Library and information science software 2790: 2427: 2386: 2261:Young, Michael; Wagner, Angela (2023), 1814: 1612: 893: 71:Ethical practice in scientific research 3336: 2955: 2579: 1692: 623:Geographic information system software 3260:Guidelines for human subject research 3113: 3065: 3017: 2739: 2648:Prah Ruger, Jennifer (October 2014). 2311: 1958: 1722: 1713: 1514:Social Sciences & Medicine (2009) 1460:that forms Research Ethic Committees. 1091:Guidelines for human subject research 915:or rules of professional practice of 888: 3106:from Harvard School of Public Health 2607: 2549: 1729:British Educational Research Journal 1688: 1686: 1684: 1660: 1658: 1656: 1383: 1166:There are several codes of conduct. 815: 727:The discipline is most developed in 712:is a discipline within the study of 73: 15: 3104:list of research participant rights 3074:. Oxford: Oxford University Press. 2791:Beecher, Henry K. (June 16, 1966). 2103:Redman, B. K.; Merz, J. F. (2008). 2077: 13: 3059: 171:{{Translated|pt|Ética na ciência}} 14: 3375: 3171:Privacy for research participants 3097: 3018:Laine, Heidi (31 December 2018). 2962:Encyclopedia of Clinical Pharmacy 2552:KRITERION – Journal of Philosophy 1911:Whitbeck, Caroline (2011-08-15). 1681: 1653: 1575:Regulation of genetic engineering 1492:have their own ethics committees. 1467:is the relevant ethics committee. 1337:privacy for research participants 1114: 792:Research in other fields such as 2956:Khaliq, Yasmin (November 2002), 2636:Medicine and Health Rhode Island 2039: 1545:Self-experimentation in medicine 1454:National Research Ethics Service 1428:This section is an excerpt from 1387: 1226:This section is an excerpt from 1120:This section is an excerpt from 978:This section is an excerpt from 958:their efficiency is criticized. 944:European Charter for Researchers 899:This section is an excerpt from 819: 716:. Its scope ranges from general 78: 20: 2991: 2949: 2907: 2892: 2874: 2833: 2784: 2462: 2421: 2387:Berdine, Gilbert (2015-01-10). 2366:from the original on 2017-05-10 2305: 2295:Principles of Biomedical Ethics 2236: 2209: 2146: 2096: 2071: 2033: 1989: 1964: 1540:Unethical human experimentation 1184:in 1973 and the development of 857:Ethics committee § History 853:Unethical human experimentation 808:may generate ethical concerns. 2793:"Ethics and Clinical Research" 2740:Ahmed, Furqaan (August 2013). 2428:Riddick, Frank (Spring 2003). 1977:. ALLEA All European Academies 1939: 1917:. Cambridge University Press. 1904: 1845: 1808: 1763: 1615:"The Moral Terrain of Science" 1606: 1560:Scientific literature § Ethics 169:You may also add the template 1: 3300:Monitoring in clinical trials 2999:Social Science & Medicine 2667:10.1136/medethics-2014-102356 2531:login.proxylib.csueastbay.edu 2011:10.1016/S0140-6736(98)07133-5 1600: 1535:Children in clinical research 1422: 1070:in the integrity of science. 3268:List of medical ethics cases 2326:10.1097/ncm.0000000000000151 2314:Professional Case Management 1723:Eaton, Sarah Elaine (2020). 1530:List of medical ethics cases 1507: 1220: 1103:derives, historically, from 1078:Office of Research Integrity 875:Tuskegee syphilis experiment 861:List of medical ethics cases 756:Tuskegee syphilis experiment 7: 2928:10.1007/978-3-031-11810-4_1 2809:10.1056/NEJM196606162742405 2711:10.2190/GYW9-XUMQ-M3K2-T31C 2564:10.13140/RG.2.2.11026.89289 2183:BMJ Evidence-Based Medicine 1523: 1498:institutional review boards 1452:In the United Kingdom, the 1172:The Declaration of Helsinki 141:will aid in categorization. 10: 3380: 3313:Institutional review board 3011: 2580:Coward, Harold G. (1999). 2195:10.1136/bmjebm-2021-111826 1465:Institutional review board 1463:In the United States, the 1427: 1379: 1294:the ethics of the ordinary 1225: 1119: 1088: 1085:Discipline specific ethics 1024:and of research ethics in 977: 898: 871:Nazi human experimentation 850: 811: 775:research ethics committees 752:Nazi human experimentation 116:Machine translation, like 3318:Data monitoring committee 3298: 3258: 3222: 3194: 3148: 2970:10.3109/9780824706081.150 1872:10.1007/s41055-017-0014-4 1776:Science and Public Policy 1699:. SAGE Publications Ltd. 1631:10.1007/s10670-013-9538-0 1613:Douglas, Heather (2014). 1590:Philosophy of engineering 650:Qualitative data analysis 93:the corresponding article 3323:Community advisory board 3245:Clinical research ethics 2406:10.12746/swrccc.v3i9.185 1923:10.1017/cbo9780511976339 1474:) and ethics committee ( 1310:Study participant rights 1305:Clinical research ethics 1131:is an applied branch of 3278:Declaration of Helsinki 2124:10.1126/science.1158052 2078:Xie, Yun (2008-08-12). 2050:: 11–18. Archived from 1500:procedures in the 1974 1441:medical experimentation 777:, such as those of the 764:Declaration of Helsinki 180:For more guidance, see 3196:Human subject research 2903:. Canadian Government. 2759:10.4292/wjgpt.v4.i3.47 1445:human subject research 1354:Vulnerable populations 1332:shared decision-making 1161:involuntary commitment 1097:Human subject research 1009:in the publication of 995: 907:Research integrity or 867:list of historic cases 798:information technology 748:list of historic cases 737:human subject research 529:Inferential statistics 475:Descriptive statistics 422:Human subject research 3066:Speid, Lorna (2010). 1829:10.1057/9780230233768 1815:Iphofen, Ron (2011). 1784:10.1093/scipol/scw069 1693:Israel, Mark (2015). 1595:Philosophy of science 1502:National Research Act 1157:involuntary treatment 1016:. It is violation of 999:Scientific misconduct 989: 980:Scientific misconduct 973:Scientific misconduct 932:scientific misconduct 313:Philosophical schools 182:Knowledge:Translation 153:copyright attribution 3141:Research participant 2610:The Dental Assistant 2487:10.2215/CJN.04780515 2360:depts.washington.edu 2048:The COPE Report 1999 1585:Ethics of technology 1365:incarcerated persons 1300:, and public health. 1298:environmental ethics 1214:culturally sensitive 1168:The Hippocratic Oath 1095:Research ethics for 1018:scientific integrity 909:scientific integrity 901:Scientific integrity 894:Scientific integrity 718:scientific integrity 638:Reference management 588:Scientific modelling 330:Critical rationalism 3166:Respect for persons 3024:Informaatiotutkimus 2434:The Ochsner Journal 2041:"Coping with fraud" 1945:Walter, Klein eds. 1565:Psychology § Ethics 1456:is the responsible 1188:in the 1960s. With 1028:, including in the 1020:: violation of the 1014:scientific research 618:Argument technology 3037:10.23978/inf.77414 2248:2021-10-22 at the 1580:Engineering ethics 1570:Information ethics 1399:. You can help by 1314:Participants in a 1176:The Nuremberg Code 996: 889:Scientific conduct 831:. You can help by 612:Tools and software 556:Secondary research 480:Discourse analysis 161:interlanguage link 39:You can assist by 3364:Scientific method 3331: 3330: 3204:Clinical research 3181:Return of results 3176:Right to withdraw 3081:978-0-19-973416-0 2937:978-3-031-11809-8 2803:(24): 1354–1360. 2699:Int J Health Serv 2616:(3): 26, 28, 36. 2229:978-93-90649-38-9 1932:978-0-521-89797-6 1838:978-0-230-29634-3 1741:10.1002/berj.3623 1706:978-1-4739-1009-6 1483:ethics committees 1417: 1416: 1342:return of results 1320:clinical research 1022:scientific method 1003:scholarly conduct 849: 848: 707: 706: 673:Philosophy portal 581:Systematic review 566:Literature review 524:Historical method 507:Social experiment 442:Scientific method 427:Narrative inquiry 278:Interdisciplinary 272:Research strategy 193: 192: 105: 101: 69: 68: 61: 3371: 3308:Ethics committee 3186:Informed consent 3134: 3127: 3120: 3111: 3110: 3085: 3073: 3055: 3053: 3052: 3039: 3006: 2995: 2989: 2988: 2987: 2986: 2953: 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