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Richard Lounsbery Award

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246:, For his work on the genetic and mechanical regulation that underlies tissue proliferation, homeostasis and repair in physiological and pathological conditions (using a combination of interdisciplinary approaches involving sophisticated imaging, genetics, large-scale molecular approaches, and computational analyses) including the mechanisms of local and long-range mechano-sensing during cytokinesis that remodel the dividing cell adherens junction. 25: 230:, for his pioneering work and leadership in the second wave of genomics that is transforming genetics and medicine. Through his development of exome sequencing and other novel technologies, he has defined new paradigms for implicating Mendelian disease genes, interpreting genetic variation, and single cell profiling of developmental lineages and gene regulation in whole organisms. 284:, for his work in Structural Biology (by X-ray diffraction and cryo-electron microscopy methods) on the regulation of gene expression at both the transcriptional level (structures of the nuclear receptors to retinoic acid and vitamin D) and the protein translation level (initiation and termination complexes, and the structure of the human ribosome). 195:, for her groundbreaking discoveries that neuronal activity promotes adaptive myelination important for cognition, and that neuronal activity drives malignant glioma progression through neuron-to-glioma synapses and paracrine factors. These contributions have elucidated new perspectives in neuroscience and pioneered the field of cancer neuroscience. 148:
in alternating years to a scientist from the other country. The award is selected by a seven-member jury representing both the French and the US Academies. The recipient receives a $ 75,000 prize, funding to visit a lab or research institution in the awarding country, and an invitation to give the
581:, for their discoveries of the mechanisms of synaptic transmission. Philippe Ascher furthered knowledge regarding the properties of glutamate receptors which play an important role in trials, and Henri Korn brought to light the elementary liberation of neurotransmitter in quanta form in the 1127: 522:, for his dissection of the biochemical mechanisms by which proteins are transferred from one cellular compartment to another and to the outside world. These mechanisms are important in neurotransmission, tissue biogenesis, and hormonal secretion. 1232: 679:, for his work in uncovering the molecular interactions that control the traffic of newly synthesized proteins in eukaryotic cells, for his incisive experiments, and for the beauty of the findings by which he established these interactions. 1157: 401:, for his contributions to the understanding the genetic basis of the predisposition to viral and bacterial diseases of childhood, which have important clinical implications for the diagnostic and management of infectious diseases. 1262: 1167: 1192: 1162: 1237: 1177: 1272: 1137: 1217: 1252: 1142: 453:, for her pioneering work on the molecular neurobiology of opioid-controlled behaviors, the results of which have very important implications for the treatment of pain, drug abuse, and emotional disorders. 1277: 1197: 1187: 697:, for his series of notable contributions in molecular genetics, which help to explain the means by which genetic information is organized and used to direct the synthesis of specific cell products. 1242: 1182: 570:, for their distinct and exciting discoveries about the pathogenesis of neurodegenerative and malignant diseases. This award is given as a celebration of the power of modern molecular medicine. 501:, for his contribution to the discovery of the molecular mechanisms implicated in the replication and repair of DNA, in particular, the discovery of a key enzyme of the DNA repair mechanism. 483:
of brain diffusion and perfusion. The method he developed permits in vivo mapping of nerve fiber bundles and has multiple applications in both medical pathology and cognitive science fields.
628:, for his original contributions in the elucidation of the mechanisms involved in malignant cell transformation, in particular, demonstration of the necessary contribution of two oncogenes. 365:, for her pioneering discoveries of the universal use of chemical communication among bacteria and the elucidation of structural and regulatory mechanisms controlling bacterial assemblies. 1257: 1152: 1132: 1339: 1227: 1267: 1222: 1212: 661:, for their seminal contributions to our understanding of the structure and function of DNA, which were essential and fundamental to the development of recombinant DNA techniques. 1172: 1147: 701: 1202: 1247: 1207: 592:, for elucidating key steps in the cell cycle, chromosome movement, cell cycle timing, nucleus breakdown and reformation, and microtubule control of cell polarity and 907: 387: 858: 610:, for his contributions, which have opened a new road in the control of oxygen transport in the blood and the treatment of the first worldwide genetic plague, 303: 234: 342: 209:, for his pioneering achievements in the field of genome editing, including the discovery of novel CRISPR systems and their development as molecular tools. 202:, for her outstanding research on the sensory interface between the central nervous system and cerebrospinal fluid that controls our posture and movements. 1001: 1102: 1071: 544:, for showing how cells and tissues differentiate during vertebrate development through studies on localized mRNAs in eggs and the genes that induce 1349: 379:, for her extraordinarily inventive and successful use of molecular and classical genetics to probe the individual nerve cell basis of behavior in 639:, for their discoveries regarding the proteins and mechanisms that mediate cellular responses to the binding of ligands to cell surface receptors. 1354: 272: 213: 1061: 796: 1359: 851: 141: 508:, for his pioneering contributions to the molecular genetics of plant architecture, which have practical implications for agriculture. 93: 706: 347: 308: 277: 239: 65: 1026: 892: 934: 35: 1344: 72: 1006: 844: 515:, for her fundamental discoveries in microbiology dealing with mechanisms of bacterial entry and intracellular host motility. 223:, for her work in developmental biology, in particular training and evolution of periodic patterns on the plumage of birds. 1329: 1319: 955: 79: 603:, for elucidating a molecular mechanism by which a single regulatory gene can lead to a program of cell differentiation. 1107: 1087: 742: 61: 902: 1293: 975: 1056: 924: 919: 50: 650:, for their fundamental work, which has contributed to the treatment of parasitic and neurological diseases. 1298: 867: 157: 783: 762: 1324: 960: 897: 480: 405: 145: 1036: 970: 822: 86: 1066: 1051: 912: 396: 392: 372:, for his work on the molecular mechanisms that underlie the formation and the remodeling of bone. 1092: 1046: 950: 316: 46: 672:, which paved the way for the solution of a series of fundamental problems in molecular biology. 315:, for his major contributions to the understanding of molecular and cellular mechanisms causing 1334: 582: 380: 530: 1097: 996: 980: 687: 505: 376: 438:, for his critical role in revealing the structural mechanisms underlying processivity in 8: 725: 690:, for their work on fundamental structures of genetic material and of the nervous system. 600: 563: 555:, for his work in human genetics and in particular for his discovery of the mutation of 152:
The Lounsbery Award was established in 1979 by Vera Lounsbery in memory of her husband,
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and particularly in the genetic and developmental mechanisms that control segmentation.
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The Award alternates between French and American scientists, and is awarded by the
676: 129:, 45 years or younger, in recognition of "extraordinary scientific achievement in 1031: 707: 665: 658: 574: 567: 512: 498: 424: 323: 643: 836: 683: 654: 636: 611: 526: 476: 192: 427:, for her major contributions in the perception and behavioral translation of 1313: 559:. This new type of mutation has now been found at the origin of the diseases. 534: 413: 288: 250: 185: 169: 119: 827: 253:, for her contributions to global health and study of emerging diseases and 694: 618: 491: 487: 435: 417: 327: 227: 199: 729: 465: 355: 262: 188:, for outstanding and innovative work in mammalian developmental biology. 161: 412:, which have elucidated a molecular pathway leading into and out of the 240: 578: 469: 461: 428: 348: 206: 494:
proteins and the relation of these proteins to human genetic diseases.
309: 291:, for her work probing the molecular basis of how adaptation to novel 784:
http://www.nasonline.org/programs/awards/richard-lounsbery-award.html
607: 556: 409: 331: 296: 254: 126: 668:, for his genetic and biochemical analysis of the maltose system of 278: 24: 545: 134: 621:, for his discoveries elucidating gene structure in animal cells. 593: 266: 130: 714: 669: 335: 123: 490:, for her fundamental insights into structure and function of 258: 165: 533:, for their contributions to the study of the regulation of 479:, for his work on the invention and development of nuclear 439: 1340:
Awards of the United States National Academy of Sciences
460:, for her pioneering biochemical and genetic studies of 797:"2020 Richard Lounsbery Prize Winner: Marie Manceau" 295:
pressures establishes and sustains diversity during
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NAS Award for the Industrial Application of Science
1128:Animal, nutritional and applied microbial sciences 1103:John J. Carty Award for the Advancement of Science 1072:William O. Baker Award for Initiatives in Research 338:allows exquisite control of the neuron with light. 1311: 866: 1007:J.C. Hunsaker Award in Aeronautical Engineering 1062:NAS Award for Chemistry in Service to Society 852: 408:, for his pioneering biochemical studies on 164:, and the couple divided their time between 51:introducing citations to additional sources 149:Lounsbery Lecture in the awarding country. 1233:Medical genetics, hematology, and oncology 859: 845: 354:, for his work in embryonic patterning in 1027:Alexander Hollaender Award in Biophysics 893:Alexander Hollaender Award in Biophysics 713:, for his work on the physiology of the 464:, the enzyme that maintains the ends of 41:Relevant discussion may be found on the 1350:1979 establishments in Washington, D.C. 935:Selman A. Waksman Award in Microbiology 830:, from the Richard Lounsbery Foundation 326:, for pioneering the technology called 1355:American science and technology awards 1312: 446:and their interacting target proteins. 160:. Richard and Vera met in Paris after 840: 1158:Biophysics and computational biology 18: 956:Arthur L. Day Prize and Lectureship 175: 13: 1263:Plant, soil, and microbial science 1163:Cellular and developmental biology 1108:NAS Award for Scientific Reviewing 442:replication and the regulation of 14: 1371: 1238:Medical physiology and metabolism 1193:Environmental science and ecology 1088:William and Katherine Estes Award 815: 743:List of biomedical science awards 903:Jessie Stevenson Kovalenko Medal 34:relies largely or entirely on a 23: 1294:National Academy of Engineering 976:Charles Doolittle Walcott Medal 330:in which insertion of a single 1360:France–United States relations 1057:NAS Award in Chemical Sciences 925:NAS Award in the Neurosciences 920:NAS Award in Molecular Biology 789: 777: 765:. National Academy of Sciences 755: 1: 1345:1979 establishments in France 748: 1299:National Academy of Medicine 1273:Social and political science 868:National Academy of Sciences 786:National Academy of Sciences 158:Richard Lounsbery Foundation 142:National Academy of Sciences 7: 1253:Physiology and pharmacology 1218:Human environmental science 736: 10: 1376: 1330:French Academy of Sciences 1320:Awards established in 1979 961:Daniel Giraud Elliot Medal 898:Gilbert Morgan Smith Medal 481:magnetic resonance imaging 146:French Academy of Sciences 1286: 1120: 1080: 1037:Comstock Prize in Physics 1015: 989: 971:Mary Clark Thompson Medal 943: 881: 874: 828:Richard Lounsbery History 763:"Richard Lounsbery Award" 62:"Richard Lounsbery Award" 1067:NAS Award in Mathematics 1052:James Craig Watson Medal 1093:Troland Research Awards 1047:J. Lawrence Smith Medal 951:Alexander Agassiz Medal 930:Richard Lounsbery Award 799:. Adademie des Sciences 156:, and is funded by the 116:Richard Lounsbery Award 583:central nervous system 908:Kimber Genetics Award 388:Jean-Laurent Casanova 1278:Systems neuroscience 1198:Evolutionary biology 1098:Public Welfare Medal 997:Gibbs Brothers Medal 981:Stanley Miller Medal 728:, for their work in 688:Jean-Pierre Changeux 537:and differentiation. 506:Elliot M. Meyerowitz 377:Cornelia I. Bargmann 317:Huntington's disease 47:improve this article 1138:Applied mathematics 726:Joseph L. Goldstein 564:Stanley B. Prusiner 1042:Henry Draper Medal 966:G. K. Warren Prize 548:and neural tissue. 531:Jacques Pouysségur 1325:Biomedical awards 1307: 1306: 1243:Microbial biology 1116: 1115: 1016:Physical Sciences 648:Jacques Glowinski 590:Marc W. Kirschner 553:Jean Louis Mandel 542:Douglas A. Melton 363:Bonnie L. Bassler 235:Yohanns Bellaïche 154:Richard Lounsbery 112: 111: 97: 1367: 1178:Computer science 916: 879: 878: 861: 854: 847: 838: 837: 823:Other NAS Awards 809: 808: 806: 804: 793: 787: 781: 775: 774: 772: 770: 759: 722:Michael S. Brown 712: 709: 633:Alfred G. Gilman 601:Harold Weintraub 520:James E. Rothman 458:Carol W. Greider 451:Brigitte Kieffer 444:tyrosine kinases 400: 353: 350: 343:Olivier Pourquié 314: 311: 283: 280: 245: 242: 222: 186:Jean-Léon Maître 176:Award recipients 107: 104: 98: 96: 55: 27: 19: 16:Scientific award 1375: 1374: 1370: 1369: 1368: 1366: 1365: 1364: 1310: 1309: 1308: 1303: 1282: 1143:Applied physics 1112: 1076: 1032:Arctowski Medal 1019: 1017: 1011: 985: 939: 910: 885: 883: 870: 865: 834: 818: 813: 812: 802: 800: 795: 794: 790: 782: 778: 768: 766: 761: 760: 756: 751: 739: 704: 666:Maxime Schwartz 659:Thomas Maniatis 585:of vertebrates. 575:Philippe Ascher 568:Bert Vogelstein 513:Pascale Cossart 499:Miroslav Radman 425:Catherine Dulac 390: 370:Gérard Karsenty 345: 334:protein into a 324:Karl Deisseroth 306: 304:Frédéric Saudou 275: 237: 216: 178: 108: 102: 99: 56: 54: 40: 28: 17: 12: 11: 5: 1373: 1363: 1362: 1357: 1352: 1347: 1342: 1337: 1332: 1327: 1322: 1305: 1304: 1302: 1301: 1296: 1290: 1288: 1284: 1283: 1281: 1280: 1275: 1270: 1265: 1260: 1255: 1250: 1245: 1240: 1235: 1230: 1225: 1220: 1215: 1210: 1205: 1200: 1195: 1190: 1185: 1180: 1175: 1170: 1165: 1160: 1155: 1150: 1145: 1140: 1135: 1130: 1124: 1122: 1118: 1117: 1114: 1113: 1111: 1110: 1105: 1100: 1095: 1090: 1084: 1082: 1078: 1077: 1075: 1074: 1069: 1064: 1059: 1054: 1049: 1044: 1039: 1034: 1029: 1023: 1021: 1013: 1012: 1010: 1009: 1004: 999: 993: 991: 987: 986: 984: 983: 978: 973: 968: 963: 958: 953: 947: 945: 944:Earth Sciences 941: 940: 938: 937: 932: 927: 922: 917: 905: 900: 895: 889: 887: 876: 872: 871: 864: 863: 856: 849: 841: 832: 831: 825: 817: 816:External links 814: 811: 810: 788: 776: 753: 752: 750: 747: 746: 745: 738: 735: 734: 733: 718: 702:François Morel 698: 691: 684:Pierre Chambon 680: 673: 662: 655:Martin Gellert 651: 640: 637:Martin Rodbell 629: 626:François Cuzin 622: 615: 612:drepanocytosis 604: 597: 586: 571: 560: 549: 538: 527:Daniel Louvard 523: 516: 509: 502: 495: 484: 477:Denis Le Bihan 473: 454: 447: 432: 421: 402: 384: 373: 366: 359: 339: 320: 300: 285: 269: 247: 231: 224: 210: 203: 196: 193:Michelle Monje 189: 177: 174: 110: 109: 45:. Please help 31: 29: 22: 15: 9: 6: 4: 3: 2: 1372: 1361: 1358: 1356: 1353: 1351: 1348: 1346: 1343: 1341: 1338: 1336: 1335:French awards 1333: 1331: 1328: 1326: 1323: 1321: 1318: 1317: 1315: 1300: 1297: 1295: 1292: 1291: 1289: 1285: 1279: 1276: 1274: 1271: 1269: 1266: 1264: 1261: 1259: 1258:Plant biology 1256: 1254: 1251: 1249: 1246: 1244: 1241: 1239: 1236: 1234: 1231: 1229: 1226: 1224: 1221: 1219: 1216: 1214: 1211: 1209: 1206: 1204: 1201: 1199: 1196: 1194: 1191: 1189: 1186: 1184: 1181: 1179: 1176: 1174: 1171: 1169: 1166: 1164: 1161: 1159: 1156: 1154: 1151: 1149: 1146: 1144: 1141: 1139: 1136: 1134: 1131: 1129: 1126: 1125: 1123: 1119: 1109: 1106: 1104: 1101: 1099: 1096: 1094: 1091: 1089: 1086: 1085: 1083: 1079: 1073: 1070: 1068: 1065: 1063: 1060: 1058: 1055: 1053: 1050: 1048: 1045: 1043: 1040: 1038: 1035: 1033: 1030: 1028: 1025: 1024: 1022: 1014: 1008: 1005: 1003: 1000: 998: 995: 994: 992: 988: 982: 979: 977: 974: 972: 969: 967: 964: 962: 959: 957: 954: 952: 949: 948: 946: 942: 936: 933: 931: 928: 926: 923: 921: 918: 914: 909: 906: 904: 901: 899: 896: 894: 891: 890: 888: 880: 877: 873: 869: 862: 857: 855: 850: 848: 843: 842: 839: 835: 829: 826: 824: 820: 819: 798: 792: 785: 780: 764: 758: 754: 744: 741: 740: 732:biosynthesis. 731: 727: 723: 719: 716: 710: 703: 699: 696: 692: 689: 685: 681: 678: 677:Günter Blobel 674: 671: 667: 663: 660: 656: 652: 649: 645: 641: 638: 634: 630: 627: 623: 620: 616: 613: 609: 605: 602: 598: 595: 591: 587: 584: 580: 576: 572: 569: 565: 561: 558: 554: 550: 547: 543: 539: 536: 535:cell division 532: 528: 524: 521: 517: 514: 510: 507: 503: 500: 496: 493: 489: 485: 482: 478: 474: 471: 467: 463: 459: 455: 452: 448: 445: 441: 437: 433: 430: 426: 422: 419: 415: 414:mitochondrion 411: 407: 406:Xiaodong Wang 403: 398: 394: 389: 385: 382: 378: 374: 371: 367: 364: 360: 357: 351: 344: 340: 337: 333: 329: 325: 321: 318: 312: 305: 301: 298: 294: 290: 289:Hopi Hoekstra 286: 281: 274: 273:Bruno Klaholz 270: 268: 264: 260: 256: 252: 251:Pardis Sabeti 248: 243: 236: 232: 229: 225: 220: 215: 214:Marie Manceau 211: 208: 204: 201: 197: 194: 190: 187: 183: 182: 181: 173: 171: 167: 163: 159: 155: 150: 147: 143: 138: 136: 132: 128: 125: 121: 117: 106: 95: 92: 88: 85: 81: 78: 74: 71: 67: 64: –  63: 59: 58:Find sources: 52: 48: 44: 38: 37: 36:single source 32:This article 30: 26: 21: 20: 1168:Neuroscience 1153:Biochemistry 1133:Anthropology 929: 833: 801:. 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