Knowledge

Robert Donald Cohen

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153:, where he worked at the endocrine and metabolic unit under Russell Fraser. At LHMC, Cohen was in 1960–1965 lecturer in medicine, in 1967–1969 senior lecturer, in 1969–1974 reader in medicine, in 1974–1982 professor of metabolic medicine, and in 1982–1995 professor of medicine and director of the academic medical unit. After LHMC merged in 1995, he was in 1995–1999 professor of medicine and director of the academic medical unit at 187:
in 1981. He was an active member of numerous medical committees. He was elected FMedSci in 1998. He chaired from 1994 to 2001 the Imperial Cancer Research Fund and played a central role in its merger in 2002 with The Cancer Research Campaign to create
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They classify as type A, the traditional variety, due to hypoxia and lack of tissue perfusion. The main theme is type B, lactic acidosis of other origins, which is considered fully with an analysis of all published causes. These are divided
149:. He qualified MRCP in 1960. In 1961 he married Barbara J. Boucher, who was also a medical student at LHMC. After junior appointments from 1958 to 1959 at the London Hospital, Robert Cohen was from 1959 to 1960 house physician at the 1398: 1388: 1368: 154: 1393: 142: 146: 1378: 1373: 1363: 1353: 105: 117:(11 October 1933 – 17 October 2014) was a British physician, professor of medicine, and one of the leading experts on metabolic medicine. 1358: 1222:
Huckabee, William E. (June 1961). "Abnormal resting blood lactate. I. The significance of hyperlactatemia in hospitalized patients".
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and maternal malnutrition of functional zonation of hepatic lobules, information that continues to inform therapeutic developments.
137:, where he graduated with first class honours in the natural science tripos. He then studied medicine from 1954 to 1958 at the 473:"Effect of Late Night Calcium Supplements on Overnight Urinary Calcium Excretion in Premenopausal and Postmenopausal Women" 305:"Changes in the extracellular fluid volume and cardiac output during the development of experimental renal hypertension" 860: 1165: 1138: 979: 958: 937: 916: 895: 841: 820: 785: 150: 138: 1383: 876: 801: 768: 1004: 559:
Barber, Barry; Cohen, Robert D.; Scholes, Maureen (1976). "A review of the London Hospital computer project".
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Rushton, W. A. H.; Cohen, R. D. (13 February 1954). "Visual purple level and the course of dark adaptation".
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introduced in 1976 what is now called the Cohen-Woods classification of the causes of lactic acidosis.
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His research was primarily focused on biochemical functions of the liver, foetal programming and
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COHEN RD (October 1963). "Water and electrolyte metabolism during the treatment of myxoedema".
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Huckabee, William E. (June 1961). "Abnormal resting blood lactate. II. Lactic acidosis".
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Upon his death Cohen was survived by his widow, a daughter, a son, and five grandsons.
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In 1961 William E. Huckabee (1926–1986) described and defined the clinical problem of
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Belchetz, P. E.; Cohen, R. D.; O'Riordan, J. L.; Tomlinson, S. (20 March 1976).
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Beech, J. S.; Williams, S. R.; Cohen, R. D.; Iles, R. A. (1 November 1989).
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Belchetz, P. E.; Lloyd, M. H.; Johns, R. G. S.; Cohen, R. D. (2 June 1973).
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Savege, T. M.; Ward, J. D.; Simpson, B. R.; Cohen, R. D. (4 January 1969).
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Cohen, R. D.; Woods, H. F. (February 1983). "Lactic acidosis revisited".
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Cohen was elected FRCP in 1971. He was chair of the editorial board of
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The Metabolic and Molecular Basis of Acquired Disease, Vols. 1 & 2
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Iles, R. A.; Cohen, R. D.; Rist, A. H.; Baron, P. G. (15 April 1977).
385:"Treatment of severe salicylate poisoning by forced alkaline diuresis" 256: 514: 44: 165:... His group were the first to demonstrate the modifications by 80:
Academic physician, medical researcher, and professor of medicine
757:. Oxford: Blackwell Scientific Publications. 1976; xii+276 pages 427:
Barnardo, D. E.; Cohen, R. D.; Iles, R. A. (7 November 1970).
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as editor with B. Lewis, K. G. M. M. Alberti, A. M. Denman:
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with P. E. Belchetz, Margaret H. Lloyd, and R. G. S. Johns:
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Fellows of the Academy of Medical Sciences (United Kingdom)
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Nephrosapiens: A History of Man's Thinking about the Kidney
661:"Idiopathic infantile hypercalcaemiaβ€”a continuing enigma" 470: 218:(1) diabetes, liver disease, and other serious diseases 702: 659:
Martin, N. D.; Snodgrass, G. J.; Cohen, R. D. (1984).
382: 429:""Idiopathic" lactic and betahydroxybutyric acidosis" 155:
Barts and The London School of Medicine and Dentistry
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Munk's Roll, Volume XII, Royal College of Physicians
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Clinical and Biochemical Aspects of Lactic Acidosis
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Clinical and Biochemical Aspects of Lactic Acidosis
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Clinical and Biochemical Aspects of Lactic Acidosis
513:with P E Belchetz, J L O'Riordan, and S Tomlinson: 339:Cohen, R. D.; Lloyd-Thomas, H. G. (6 August 1966). 89:
Clinical and Biochemical Aspects of Lactic Acidosis
580: 558: 381:with T. M. Savege, J. D. Ward, and B. R. Simpson: 303:Ledingham, J. M.; Cohen, R. D. (25 January 1964). 426: 338: 1335: 929:Corpus Hominis: Memoirs of an Academic Physician 1183:"Some Acid Problems: The Bradshaw Lecture 1981" 1052: 302: 133:, Bristol, Cohen studied from 1951 to 1954 at 1389:Commanders of the Order of the British Empire 1369:Alumni of the London Hospital Medical College 971:Ladders: The History and Science of Elevation 1291: 1002: 701:with J S Beech, S R Williams, and R A Iles: 242: 157:. He retired as professor emeritus in 1999. 1394:Fellows of the Royal College of Physicians 628: 1321: 1198: 1082: 728: 684: 606: 540: 496: 452: 408: 364: 341:"Exercise electrocardiogram in myxoedema" 320: 220:(2) phenformin, fructose, and other drugs 579:with R A Iles, A H Rist, and P G Baron: 279: 226: 657:with N. D. Martin and G. J. Snodgrass: 557:with Barry Barber and Maureen Scholes: 1336: 1154:Cohen, Robert D. (28 September 2014). 1127:Cohen, Robert D. (28 September 2014). 1104: 1102: 1100: 1098: 1096: 1094: 812:Man and the Liver from Myth to Science 1180: 1160:. Troubador Publishing. p. 143. 1153: 1133:. Troubador Publishing. p. 142. 1126: 996: 967: 946: 925: 904: 883: 850: 829: 808: 1379:21st-century British medical doctors 1374:20th-century British medical doctors 1364:Alumni of Trinity College, Cambridge 425:with D. E. Barnardo and R. A. Iles: 1354:People educated at Plymouth College 1091: 780:. London: BailliΓ¨re Tindall. 1990. 13: 1359:People educated at Clifton College 198: 14: 1410: 151:Royal Postgraduate Medical School 855:. Troubador Publishing Limited. 665:Archives of Disease in Childhood 192:. He was appointed CBE in 1997. 1059:by R. D. Cohen and H. F. Woods" 183:from 1973 to 1975. He gave the 139:London Hospital Medical College 1285: 1250: 1215: 1174: 1147: 1120: 1046: 129:and then from 1947 to 1951 at 1: 1292:Baron, D. N. (January 1977). 1024:10.1016/s0140-6736(15)60673-0 989: 141:(LHMC). He graduated in 1958 1271:10.1016/0002-9343(61)90172-3 1236:10.1016/0002-9343(61)90171-1 120: 7: 1181:Cohen, R. D. (April 1982). 853:Splancreas: And Other Offal 517:"Factitious hypercalcaemia" 231: 10: 1415: 875:: CS1 maint: postscript ( 800:: CS1 maint: postscript ( 767:: CS1 maint: postscript ( 135:Trinity College, Cambridge 94:Cohen-Woods classification 968:Cohen, Robert D. (2014). 947:Cohen, Robert D. (2014). 926:Cohen, Robert D. (2013). 905:Cohen, Robert D. (2013). 884:Cohen, Robert D. (2013). 851:Cohen, Robert D. (2013). 830:Cohen, Robert D. (2012). 809:Cohen, Robert D. (2011). 573:10.3109/14639237609017805 337:with H. G. Lloyd-Thomas: 84: 76: 68: 52: 30: 23: 1187:J R Coll Physicians Lond 1075:10.1136/bmj.2.6038.762-c 1053:Williams, Roger (1976). 974:. Troubador Publishing. 953:. Troubador Publishing. 932:. Troubador Publishing. 911:. Troubador Publishing. 890:. Troubador Publishing. 836:. Troubador Publishing. 815:. Troubador Publishing. 746: 445:10.1136/bmj.4.5731.348-a 1193:(2): 69–73, &6–77. 533:10.1136/bmj.1.6011.690 489:10.1136/bmj.2.5865.510 357:10.1136/bmj.2.5509.327 301:with J. M. Ledingham: 224: 175: 1384:British hepatologists 1314:10.1136/jcp.30.1.92-d 1110:"Robert Donald Cohen" 1005:"Robert Donald Cohen" 1003:Watts, Geoff (2015). 752:with H. Frank Woods: 643:10.2337/diab.32.2.181 401:10.1136/bmj.1.5635.35 227:Selected publications 213: 159: 677:10.1136/adc.59.7.605 950:Movement and Motion 709:Biochemical Journal 587:Biochemical Journal 561:Medical Informatics 298:(Cohen's MD thesis) 163:acid base disorders 125:After education at 102:Robert Donald Cohen 25:Robert Donald Cohen 190:Cancer Research UK 171:metabolic acidosis 143:MB BChir (Cantab.) 721:10.1042/bj2630737 599:10.1042/bj1640185 527:(6011): 690–691. 483:(5865): 510–512. 439:(5731): 348–349. 351:(5509): 327–330. 251:(4398): 301–302. 167:diabetes mellitus 99: 98: 16:British physician 1406: 1328: 1327: 1325: 1289: 1283: 1282: 1254: 1248: 1247: 1219: 1213: 1212: 1202: 1178: 1172: 1171: 1151: 1145: 1144: 1124: 1118: 1117: 1106: 1089: 1088: 1086: 1050: 1044: 1043: 1009: 1000: 985: 964: 943: 922: 901: 887:A Muscle Odyssey 880: 874: 866: 847: 826: 805: 799: 791: 772: 766: 758: 742: 732: 698: 688: 654: 620: 610: 576: 554: 544: 510: 500: 466: 456: 422: 412: 378: 368: 334: 324: 297: 282:Clinical Science 276: 257:10.1038/173301a0 239:W. A. H. Rushton 185:Bradshaw Lecture 180:Clinical Science 127:Plymouth College 116: 59: 40: 38: 21: 20: 1414: 1413: 1409: 1408: 1407: 1405: 1404: 1403: 1334: 1333: 1332: 1331: 1290: 1286: 1255: 1251: 1220: 1216: 1179: 1175: 1168: 1152: 1148: 1141: 1125: 1121: 1108: 1107: 1092: 1051: 1047: 1007: 1001: 997: 992: 982: 961: 940: 919: 898: 868: 867: 863: 844: 823: 793: 792: 788: 776: 760: 759: 753: 749: 395:(5635): 35–36. 309:Can Med Assoc J 234: 229: 222:(3) hereditary. 221: 219: 217: 205:lactic acidosis 201: 199:Lactic acidosis 131:Clifton College 123: 104: 92: 64: 63:London, England 61: 57: 56:17 October 2014 48: 42: 41:11 October 1933 36: 34: 26: 17: 12: 11: 5: 1412: 1402: 1401: 1396: 1391: 1386: 1381: 1376: 1371: 1366: 1361: 1356: 1351: 1346: 1330: 1329: 1284: 1265:(6): 840–848. 1249: 1230:(6): 833–839. 1214: 1173: 1166: 1157:Corpus Hominis 1146: 1139: 1130:Corpus Hominis 1119: 1090: 1045: 1018:(9975): 1288. 994: 993: 991: 988: 987: 986: 980: 965: 959: 944: 938: 923: 917: 908:Skin and Bones 902: 896: 881: 862:978-1780883960 861: 848: 842: 827: 821: 806: 786: 773: 748: 745: 744: 743: 715:(3): 737–744. 699: 671:(7): 605–613. 655: 637:(2): 181–191. 625:H. Frank Woods 621: 593:(1): 185–191. 577: 555: 511: 467: 423: 379: 335: 315:(4): 292–294. 299: 277: 233: 230: 228: 225: 209:H. Frank Woods 200: 197: 147:M.D. (Cantab.) 122: 119: 97: 96: 86: 85:Known for 82: 81: 78: 74: 73: 70: 66: 65: 62: 60:(aged 81) 54: 50: 49: 43: 32: 28: 27: 24: 15: 9: 6: 4: 3: 2: 1411: 1400: 1397: 1395: 1392: 1390: 1387: 1385: 1382: 1380: 1377: 1375: 1372: 1370: 1367: 1365: 1362: 1360: 1357: 1355: 1352: 1350: 1347: 1345: 1342: 1341: 1339: 1324: 1319: 1315: 1311: 1307: 1303: 1302:J Clin Pathol 1299: 1297: 1288: 1280: 1276: 1272: 1268: 1264: 1260: 1253: 1245: 1241: 1237: 1233: 1229: 1225: 1218: 1210: 1206: 1201: 1196: 1192: 1188: 1184: 1177: 1169: 1167:9781783060672 1163: 1159: 1158: 1150: 1142: 1140:9781783060672 1136: 1132: 1131: 1123: 1115: 1111: 1105: 1103: 1101: 1099: 1097: 1095: 1085: 1080: 1076: 1072: 1069:(6038): 762. 1068: 1064: 1060: 1058: 1049: 1041: 1037: 1033: 1029: 1025: 1021: 1017: 1013: 1006: 999: 995: 983: 981:9781783063253 977: 973: 972: 966: 962: 960:9781784620004 956: 952: 951: 945: 941: 939:9781783060672 935: 931: 930: 924: 920: 918:9781780884936 914: 910: 909: 903: 899: 897:9781780884738 893: 889: 888: 882: 878: 872: 864: 858: 854: 849: 845: 843:9781780882192 839: 835: 834: 828: 824: 822:9781848767966 818: 814: 813: 807: 803: 797: 789: 787:0-7020-1493-1 783: 779: 774: 770: 764: 756: 751: 750: 740: 736: 731: 726: 722: 718: 714: 710: 706: 700: 696: 692: 687: 682: 678: 674: 670: 666: 662: 656: 652: 648: 644: 640: 636: 632: 626: 622: 618: 614: 609: 604: 600: 596: 592: 588: 584: 578: 574: 570: 566: 562: 556: 552: 548: 543: 538: 534: 530: 526: 522: 518: 512: 508: 504: 499: 494: 490: 486: 482: 478: 474: 468: 464: 460: 455: 450: 446: 442: 438: 434: 430: 424: 420: 416: 411: 406: 402: 398: 394: 390: 386: 380: 376: 372: 367: 362: 358: 354: 350: 346: 342: 336: 332: 328: 323: 318: 314: 310: 306: 300: 295: 291: 287: 283: 278: 274: 270: 266: 262: 258: 254: 250: 246: 240: 236: 235: 223: 212: 210: 206: 196: 193: 191: 186: 182: 181: 174: 172: 168: 164: 158: 156: 152: 148: 144: 140: 136: 132: 128: 118: 115: 111: 107: 103: 95: 90: 87: 83: 79: 77:Occupation(s) 75: 71: 67: 55: 51: 47:, England, UK 46: 33: 29: 22: 19: 1305: 1301: 1295: 1287: 1262: 1258: 1252: 1227: 1223: 1217: 1190: 1186: 1176: 1156: 1149: 1129: 1122: 1113: 1066: 1062: 1056: 1048: 1015: 1011: 998: 970: 949: 928: 907: 886: 852: 832: 811: 790:; 2082 pages 777: 754: 712: 708: 668: 664: 634: 630: 590: 586: 567:(1): 61–72. 564: 560: 524: 520: 480: 476: 436: 432: 392: 388: 348: 344: 312: 308: 285: 281: 248: 244: 214: 207:. Cohen and 202: 194: 179: 176: 160: 145:and in 1966 124: 101: 100: 88: 58:(2014-10-17) 18: 1349:2014 deaths 1344:1933 births 1294:"Review of 1055:"Review of 865:; 160 pages 288:: 293–304. 69:Nationality 1338:Categories 1012:The Lancet 990:References 37:1933-10-11 1308:(1): 92. 871:cite book 796:cite book 763:cite book 121:Biography 1279:13716482 1259:Am J Med 1244:13716482 1224:Am J Med 1063:Br Med J 1040:39187147 1032:25890905 631:Diabetes 521:Br Med J 477:Br Med J 433:Br Med J 389:Br Med J 345:Br Med J 331:14111738 294:14070913 265:13144746 232:Articles 45:Plymouth 1209:7077566 1200:5377755 1084:1688799 739:2512912 730:1133494 695:6465928 686:1628928 651:6337898 608:1164773 551:1252885 542:1639109 507:4714465 498:1589586 463:5472807 454:1819685 419:5761895 410:1981842 375:5920653 366:1943154 322:1922480 273:5276567 114:FMedSci 72:British 1323:476665 1320:  1277:  1242:  1207:  1197:  1164:  1137:  1081:  1038:  1030:  978:  957:  936:  915:  894:  859:  840:  819:  784:  737:  727:  693:  683:  649:  615:  605:  549:  539:  505:  495:  461:  451:  417:  407:  373:  363:  329:  319:  292:  271:  263:  245:Nature 91:(1976) 1036:S2CID 1008:(PDF) 747:Books 623:with 617:18143 269:S2CID 237:with 216:into: 112: 108: 1275:PMID 1240:PMID 1205:PMID 1162:ISBN 1135:ISBN 1028:PMID 976:ISBN 955:ISBN 934:ISBN 913:ISBN 892:ISBN 877:link 857:ISBN 838:ISBN 817:ISBN 802:link 782:ISBN 769:link 735:PMID 691:PMID 647:PMID 613:PMID 547:PMID 503:PMID 459:PMID 415:PMID 371:PMID 327:PMID 290:PMID 261:PMID 110:FRCP 53:Died 31:Born 1318:PMC 1310:doi 1267:doi 1232:doi 1195:PMC 1079:PMC 1071:doi 1020:doi 1016:385 725:PMC 717:doi 713:263 681:PMC 673:doi 639:doi 603:PMC 595:doi 591:164 569:doi 537:PMC 529:doi 493:PMC 485:doi 449:PMC 441:doi 405:PMC 397:doi 361:PMC 353:doi 317:PMC 253:doi 249:173 106:CBE 1340:: 1316:. 1306:30 1304:. 1300:. 1273:. 1263:30 1261:. 1238:. 1228:30 1226:. 1203:. 1191:16 1189:. 1185:. 1112:. 1093:^ 1077:. 1065:. 1061:. 1034:. 1026:. 1014:. 1010:. 873:}} 869:{{ 798:}} 794:{{ 765:}} 761:{{ 733:. 723:. 711:. 707:. 689:. 679:. 669:59 667:. 663:. 645:. 635:32 633:. 627:: 611:. 601:. 589:. 585:. 563:. 545:. 535:. 523:. 519:. 501:. 491:. 479:. 475:. 457:. 447:. 435:. 431:. 413:. 403:. 391:. 387:. 369:. 359:. 347:. 343:. 325:. 313:90 311:. 307:. 286:25 284:. 267:. 259:. 247:. 241:: 169:, 1326:. 1312:: 1298:" 1281:. 1269:: 1246:. 1234:: 1211:. 1170:. 1143:. 1116:. 1087:. 1073:: 1067:2 1042:. 1022:: 984:. 963:. 942:. 921:. 900:. 879:) 846:. 825:. 804:) 771:) 741:. 719:: 697:. 675:: 653:. 641:: 619:. 597:: 575:. 571:: 565:1 553:. 531:: 525:1 509:. 487:: 481:2 465:. 443:: 437:4 421:. 399:: 393:1 377:. 355:: 349:2 333:. 296:. 275:. 255:: 39:) 35:(

Index

Plymouth
Cohen-Woods classification
CBE
FRCP
FMedSci
Plymouth College
Clifton College
Trinity College, Cambridge
London Hospital Medical College
MB BChir (Cantab.)
M.D. (Cantab.)
Royal Postgraduate Medical School
Barts and The London School of Medicine and Dentistry
acid base disorders
diabetes mellitus
metabolic acidosis
Clinical Science
Bradshaw Lecture
Cancer Research UK
lactic acidosis
H. Frank Woods
W. A. H. Rushton
doi
10.1038/173301a0
PMID
13144746
S2CID
5276567
PMID
14070913

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