1469:(IFN-α, IFN-ß) bind to receptors, cause signaling via kinases, phosphorylate and activate the Jak kinases TYK2 and JAK1 and also STAT1 and STAT2. STAT molecules form dimers and bind to ISGF3G/IRF-9, which is Interferon stimulated gene factor 3 complex with Interferon regulatory Factor 9. This allows STAT1 to enter the nucleus. STAT1 has a key role in many gene expressions that cause survival of the cell, viability or pathogen response. There are two possible transcripts (due to alternative splicing) that encode 2 isoforms of STAT1. STAT1α, the full-length version of the protein, is the main active isoform, responsible for most of the known functions of STAT1. STAT1ß, which lacks a portion of the C-terminus of the protein, is less-studied, but has variously been reported to negatively regulate activation of STAT1 or to mediate IFN-γ-dependent anti-tumor and anti-infection activities.
316:
293:
1580:
viral infections and impaired IFN a, b, g and IL27 responses are diagnosed. In partial form there can also be found high levels of IFNg in blood serum. When tested from whole blood, monocytes do not respond to BCG and IFNg doses with IL-12 production. In complete recessive form there is a very low response to anti-viral and antimycotical medication. Second, partial STAT1 deficiency can also be an autosomal dominant mutation; phenotypically causing impaired IFNg responses and causing patients to suffer with selective intracellular bacterial diseases (MSMD).
1584:
patients were showing propensity to mycobacterial infections. Another case reported was about an autosomal recessive form. 2 related patients had a homozygous missense STAT1 mutation which caused impaired splicing, therefore a defect in mature protein. Patients had partially damaged response to both IFNa and IFNg. Scientists now claim that recessive STAT1 deficiency is a new form of primary immunodeficiency and whenever a patient suffers sudden, severe and unexpected bacterial and viral infections, should be considered as potentially STAT1 deficient.
215:
190:
567:
322:
221:
4162:
4177:
31:
1655:
increased phosphorylation because of impossible dephosphorylation in nucleus. These processes are dependent on cytokines like interferon alpha or beta, interferon gamma or interleukin 27. As mentioned above, low levels of interleukin 17A were observed, therefore impaired the Th17 polarization of the immune response.
1579:
STAT1 loss of function, therefore STAT1 deficiency can have many variants. There are two main genetic impairments that can cause response to interferons type I and III. First there can be autosomal recessive partial or even complete deficiency of STAT1. That causes intracellular bacterial diseases or
2582:
Dupuis S, Jouanguy E, Al-Hajjar S, Fieschi C, Al-Mohsen IZ, Al-Jumaah S, Yang K, Chapgier A, Eidenschenk C, Eid P, Al
Ghonaium A, Tufenkeji H, Frayha H, Al-Gazlan S, Al-Rayes H, Schreiber RD, Gresser I, Casanova JL (March 2003). "Impaired response to interferon-alpha/beta and lethal viral disease in
2532:
Toubiana J, Okada S, Hiller J, Oleastro M, Lagos Gomez M, Aldave
Becerra JC, Ouachée-Chardin M, Fouyssac F, Girisha KM, Etzioni A, Van Montfrans J, Camcioglu Y, Kerns LA, Belohradsky B, Blanche S, Bousfiha A, Rodriguez-Gallego C, Meyts I, Kisand K, Reichenbach J, Renner ED, Rosenzweig S, Grimbacher
1599:
and recessive for the other. It impaired the nuclear accumulation of GAF but not of ISGF3 in cells stimulated by interferons, implying that the antimycobacterial but not the antiviral effects of human interferons are mediated by GAF. More recently, two patients have been identified with homozygous
1462:
All STAT molecules are phosphorylated by receptor associated kinases, that causes activation, dimerization by forming homo- or heterodimers and finally translocate to nucleus to work as transcription factors. Specifically STAT1 can be activated by several ligands such as
Interferon alpha (IFNα),
3028:
Reuter TY, Medhurst AL, Waisfisz Q, Zhi Y, Herterich S, Hoehn H, Gross HJ, Joenje H, Hoatlin ME, Mathew CG, Huber PA (October 2003). "Yeast two-hybrid screens imply involvement of
Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport".
1654:
With various genomic and genetic methods was discovered, that a heterozygous gain of function mutation of STAT1 is a cause of more than a half CMC cases. This mutation is caused by defect in the coiled-coil domain, domain that binds DNA, N-terminal domain or SH2 domain. Because of this there is
1570:
Mutations in the STAT1 molecule can be gain of function (GOF) or loss of function (LOF). Both of them can cause different phenotypes and symptoms. Recurring common infections are frequent in both GOF and LOF mutations. In humans STAT1 has been particularly under strong purifying selection when
1590:
induce the formation of two transcriptional activators: gamma-activating factor (GAF) and interferon-stimulated gamma factor 3 (ISGF3). A natural heterozygous germline STAT1 mutation associated with susceptibility to mycobacterial but not viral disease was found in two unrelated patients with
1583:
In knock-out mice prepared in the 90s, a low amount of CD4 and CD25 regulatory T-cells and almost no IFNa, b and g response was discovered, which lead to parasital, viral and bacterial infections. The very first reported case of STAT1 deficiency in human was an autosomal dominant mutation and
57:
1608:
Gain of function mutation was first discovered in patients with chronic mucocutaneous candidiasis (CMC). This disease is characteristic with its symptoms as persistent infections of the skin, mucosae - oral or genital and nails infections caused by
2485:
2332:
Lu HF, Yang JS, Lin YT, Tan TW, Ip SW, Li YC, Tsou MF, Chung JG (2007). "Diallyl disulfide induced signal transducer and activator of transcription 1 expression in human colon cancer colo 205 cells using differential display RT-PCR".
1670:. Besides common viral and bacterial infections, these patients develop autoimmunities or even carcinomas. It is very complicated to find a treatment because of various symptoms and resistances, inhibitors of JAK/STAT pathway such as
1600:
STAT-1 mutations who developed both post–BCG vaccination disseminated disease and lethal viral infections. The mutations in these patients caused a complete lack of STAT-1 and resulted in a lack of formation of both GAF and ISGF3.
3118:"The WD motif-containing protein receptor for activated protein kinase C (RACK1) is required for recruitment and activation of signal transducer and activator of transcription 1 through the type I interferon receptor"
329:
228:
3532:"Distinct roles of the NH2- and COOH-terminal domains of the protein inhibitor of activated signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction"
4217:
3491:"Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin"
2493:
2436:
Chapgier A, Kong XF, Boisson-Dupuis S, Jouanguy E, Averbuch D, Feinberg J, Zhang SY, Bustamante J, Vogt G, Lejeune J, Mayola E, de
Beaucoudrey L, Abel L, Engelhard D, Casanova JL (June 2009).
2940:"Identification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activation"
1647:. When T-cell deficient, these autoimmune díseases are very common. CMC was also reported as a common symptom in patients with hyper immunoglobulin E syndrome (hyper-IgE) and with
4210:
10040:
5139:
9629:
4203:
2522:
Dupuis S, Jouanguy E, Al Hajjar S, et al. Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency. Nat Genet. 2003;33(3):388–391.
10186:
5638:
10035:
2513:
Dupuis S, Dargemont C, Fieschi C, et al. Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation. Science. 2001;293(5528):300–303.
9970:
3878:
Spiekermann K, Biethahn S, Wilde S, Hiddemann W, Alves F (August 2001). "Constitutive activation of STAT transcription factors in acute myelogenous leukemia".
3632:"Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways"
3921:
Cirri P, Chiarugi P, Marra F, Raugei G, Camici G, Manao G, Ramponi G (October 1997). "c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells".
3843:
Gunaje JJ, Bhat GJ (October 2001). "Involvement of tyrosine phosphatase PTP1D in the inhibition of interleukin-6-induced Stat3 signaling by alpha-thrombin".
10466:
9661:
4046:
Kisseleva T, Bhattacharya S, Braunstein J, Schindler CW (February 2002). "Signaling through the JAK/STAT pathway, recent advances and future challenges".
10105:
3429:"Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma"
1155:
151:
10120:
7845:
1136:
10176:
10070:
2533:
B, van de
Veerdonk FL, Traidl-Hoffmann C, Picard C, Marodi L, Morio T, Kobayashi M, Lilic D, Milner JD, Holland S, Casanova JL, Puel A (June 2016).
10878:
10202:
6523:
5545:
5540:
5535:
10664:
10085:
10080:
10075:
10065:
5184:
10339:
10197:
10166:
10130:
5169:
4855:
10252:
10217:
1897:
2844:"Stat1-vitamin D receptor interactions antagonize 1,25-dihydroxyvitamin D transcriptional activity and enhance stat1-mediated transcription"
2628:"Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes"
1879:
10989:
10684:
10293:
10283:
10273:
10207:
10156:
5678:
1969:
Baris S, Alroqi F, Kiykim A, Karakoc-Aydiner E, Ogulur I, Ozen A, Charbonnier LM, Bakır M, Boztug K, Chatila TA, Barlan IB (October 2016).
10918:
10908:
10898:
10835:
10560:
10263:
9473:
9457:
4276:
54:
2981:"The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors"
10913:
10830:
10795:
10540:
10312:
10045:
9963:
5530:
1373:
10855:
10030:
8246:
8241:
8236:
8231:
8226:
5315:
5308:
5303:
5291:
5286:
5281:
5276:
5271:
5199:
1380:
10655:
10644:
10620:
10110:
9654:
9195:
7318:
10489:
8406:
8401:
8351:
8341:
8321:
8306:
8286:
8211:
8191:
7333:
7328:
5994:
1727:
1625:), also with infections of the respiratory system and skin. In these patients we can also find viral infections caused mostly by
1619:. CMC may very often result from primary immunodeficiency. Patients with CMC often suffer also with bacterial infections (mostly
9999:
7562:
7520:
7515:
7510:
7448:
7282:
7070:
7021:
7016:
5063:
5053:
1756:
1463:
Interferon gamma (IFNγ), Epidermal Growth Factor (EGF), Platelet
Derived Growth Factor (PDGF), Interleukin 6 (IL-6), or IL-27.
3339:"Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment"
10146:
9956:
4141:
1862:
11039:
10278:
1571:
populations shifted from hunting and gathering to farming, because this went along with a change in the pathogen spectrum.
2020:"Towards unravelling biological mechanisms behind radiation-induced oral mucositis via mass spectrometry-based proteomics"
1917:"Towards unravelling biological mechanisms behind radiation-induced oral mucositis via mass spectrometry-based proteomics"
9804:
9647:
8958:
4850:
4422:
3159:"The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex"
2097:"STAT1 - Signal transducer and activator of transcription 1-alpha/beta - Homo sapiens (Human) - STAT1 gene & protein"
1841:
1658:
Patients with STAT1 gain of function mutation and CMC poorly or not at all respond to treatment with azole drugs such as
4161:
3958:"Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation"
3722:"Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha"
2146:"Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells"
10010:
9752:
9227:
8126:
6213:
1651:
type I. There was reported an interleukin 17A role, because of low levels of IL-17A producing T-cells in CMC patients.
3681:"Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR"
10964:
9837:
5671:
5666:
5594:
5584:
4461:
4451:
4286:
3763:"Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells"
2420:
2410:
1648:
315:
5589:
5503:
3804:"Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5"
1721:
3290:"Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex"
2362:"Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes"
8525:
5801:
5791:
4392:
4271:
4176:
3200:"Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling"
2144:
Baran-Marszak F, Feuillard J, Najjar I, Le
Clorennec C, Béchet JM, Dusanter-Fourt I, et al. (October 2004).
1866:
1845:
292:
11059:
10675:
10377:
6156:
5796:
5491:
1539:
lement) promoter element. In either case, binding of the promoter element leads to an increased expression of
1200:
2236:"STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity"
9890:
9438:
9433:
8584:
5496:
1768:
2187:"STAT1β enhances STAT1 function by protecting STAT1α from degradation in esophageal squamous cell carcinoma"
1181:
11064:
10979:
9533:
7869:
6019:
5572:
5562:
1644:
214:
189:
131:
2938:
Xia L, Wang L, Chung AS, Ivanov SS, Ling MY, Dragoi AM, Platt A, Gilmer TM, Fu XY, Chin YE (August 2002).
2486:"Defects of STAT1 in Human. Loss of Function exposes to Mycobacteria. Gain of Function exposes to Candida"
8038:
8033:
7584:
5661:
5579:
5567:
4643:
3064:
Pang Q, Christianson TA, Keeble W, Diaz J, Faulkner GR, Reifsteck C, Olson S, Bagby GC (September 2001).
1683:
3630:
Wong AH, Tam NW, Yang YL, Cuddihy AR, Li S, Kirchhoff S, Hauser H, Decker T, Koromilas AE (March 1997).
704:
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
328:
227:
10969:
10611:
9670:
5774:
4772:
2121:"STAT1 signal transducer and activator of transcription 1 [Homo sapiens (human)] - Gene - NCBI"
1631:
4075:
Joseph AM, Kumar M, Mitra D (January 2005). "Nef: "necessary and enforcing factor" in HIV infection".
1971:"Severe Early-Onset Combined Immunodeficiency due to Heterozygous Gain-of-Function Mutations in STAT1"
321:
220:
10570:
9709:
9190:
6071:
6056:
6039:
6034:
6029:
6024:
5935:
5910:
5786:
5698:
5688:
4845:
4318:
4134:
2979:
Pang Q, Fagerlie S, Christianson TA, Keeble W, Faulkner G, Diaz J, Rathbun RK, Bagby GC (July 2000).
118:
4195:
3380:"Ser727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation"
3066:"The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality"
2896:"ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases"
122:, CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91, signal transducer and activator of transcription 1
11044:
9704:
8932:
8567:
8083:
7656:
7495:
6430:
6425:
6410:
5885:
5860:
5742:
5693:
5486:
4877:
4343:
3249:"Adenovirus E1A down-regulates LMP2 transcription by interfering with the binding of stat1 to IRF1"
2687:"Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation"
2234:
Semper C, Leitner NR, Lassnig C, Parrini M, Mahlakõiv T, Rammerstorfer M, et al. (June 2014).
1307:
1299:
1295:
139:
3337:
Takeda A, Hamano S, Yamanaka A, Hanada T, Ishibashi T, Mak TW, Yoshimura A, Yoshida H (May 2003).
10323:
10019:
9297:
7338:
6655:
5769:
5757:
3761:
Dumler I, Kopmann A, Wagner K, Mayboroda OA, Jerke U, Dietz R, Haller H, Gulba DC (August 1999).
2535:"Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype"
816:
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
1337:
1333:
1303:
1274:
1270:
11049:
10708:
9428:
7475:
7470:
5865:
5762:
5557:
5518:
4581:
4230:
4009:
Cebulla CM, Miller DM, Sedmak DD (2000). "Viral inhibition of interferon signal transduction".
10520:
10515:
9678:
9420:
8980:
5779:
5715:
5710:
5523:
4599:
1621:
10635:
10471:
9001:
8993:
6831:
6313:
5838:
5833:
5828:
5508:
5391:
4226:
4127:
3891:
3543:
3440:
2796:
2639:
1709:
1440:
203:
159:
2069:
8:
10586:
10476:
10368:
9315:
9019:
8715:
6918:
6123:
5705:
5683:
5656:
5618:
5552:
1715:
1481:
3591:"Focal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesion"
3547:
3444:
3378:
Zhang JJ, Zhao Y, Chait BT, Lathem WW, Ritzi M, Knippers R, Darnell JE (December 1998).
2800:
2643:
2360:
Deschamps M, Laval G, Fagny M, Itan Y, Abel L, Casanova JL, et al. (January 2016).
2046:
2019:
1943:
1916:
10500:
10495:
10461:
10456:
10402:
9990:
9982:
8853:
4034:
3903:
3656:
3631:
3404:
3379:
3095:
2760:
2735:
2608:
2559:
2534:
2462:
2437:
2386:
2361:
2314:
2260:
2235:
2211:
2186:
1995:
1970:
1477:
163:
4114:
4059:
3314:
3289:
3224:
3199:
3042:
2868:
2843:
1070:
1065:
1060:
1055:
1050:
1045:
1040:
1035:
1030:
1025:
1020:
1015:
1010:
1005:
1000:
995:
990:
985:
980:
975:
970:
965:
960:
955:
950:
945:
940:
935:
930:
925:
920:
915:
910:
905:
900:
895:
890:
885:
880:
875:
870:
865:
860:
855:
850:
845:
840:
835:
830:
825:
820:
815:
810:
805:
800:
795:
790:
774:
769:
764:
759:
754:
749:
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739:
734:
718:
713:
708:
698:
693:
688:
683:
678:
673:
668:
663:
658:
653:
648:
643:
638:
633:
623:
618:
613:
608:
11054:
10928:
9979:
9742:
9696:
8435:
8426:
8063:
7011:
5752:
5747:
4092:
4063:
4026:
3987:
3982:
3973:
3957:
3938:
3895:
3860:
3825:
3784:
3743:
3702:
3661:
3612:
3571:
3566:
3531:
3512:
3468:
3463:
3428:
3409:
3360:
3319:
3270:
3229:
3180:
3139:
3116:
Usacheva A, Smith R, Minshall R, Baida G, Seng S, Croze E, Colamonici O (June 2001).
3087:
3046:
3010:
3005:
2996:
2980:
2961:
2917:
2873:
2824:
2819:
2784:
2783:
Zhang JJ, Vinkemeier U, Gu W, Chakravarti D, Horvath CM, Darnell JE (December 1996).
2765:
2716:
2711:
2686:
2667:
2662:
2627:
2600:
2564:
2467:
2416:
2391:
2342:
2306:
2265:
2216:
2167:
2051:
2000:
1948:
1559:
1512:
1473:
1466:
111:
47:
4038:
3907:
3099:
2859:
2612:
2318:
10581:
10510:
10505:
10393:
10050:
6962:
6944:
5513:
5460:
5234:
4084:
4055:
4018:
3977:
3969:
3930:
3887:
3852:
3815:
3774:
3733:
3692:
3651:
3643:
3602:
3561:
3551:
3502:
3458:
3448:
3399:
3391:
3350:
3309:
3301:
3260:
3219:
3211:
3170:
3129:
3077:
3038:
3000:
2992:
2951:
2907:
2863:
2855:
2814:
2804:
2755:
2747:
2706:
2698:
2657:
2647:
2592:
2554:
2546:
2457:
2449:
2381:
2373:
2296:
2255:
2247:
2206:
2198:
2157:
2041:
2031:
1990:
1982:
1938:
1928:
1792:
1615:
1488:
408:
339:
283:
238:
143:
10959:
10936:
10481:
10398:
10161:
9103:
8326:
8196:
7360:
3355:
3338:
3157:
Usacheva A, Tian X, Sandoval R, Salvi D, Levy D, Colamonici OR (September 2003).
2550:
876:
negative regulation of metanephric nephron tubule epithelial cell differentiation
383:
167:
3175:
3158:
2018:
Subedi P, Huber K, Sterr C, Dietz A, Strasser L, Kaestle F, et al. (2023).
1915:
Subedi P, Huber K, Sterr C, Dietz A, Strasser L, Kaestle F, et al. (2023).
1902:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1884:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1635:
or environmental bacteria. Very common are also autoimmune symptoms like type 1
10820:
10810:
10737:
10354:
10344:
10268:
10100:
9948:
9737:
9732:
9727:
9200:
7480:
7463:
5606:
5261:
4258:
3536:
Proceedings of the National Academy of Sciences of the United States of America
3433:
Proceedings of the National Academy of Sciences of the United States of America
3395:
2789:
Proceedings of the National Academy of Sciences of the United States of America
2632:
Proceedings of the National Academy of Sciences of the United States of America
2377:
2162:
2145:
484:
3647:
2785:"Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling"
2736:"Stat1 associates with c-kit and is activated in response to stem cell factor"
2036:
1986:
1933:
1629:, that also affect the skin. The mycobacterial infections are often caused by
796:
metanephric mesenchymal cell proliferation involved in metanephros development
566:
11033:
10388:
10171:
10090:
9639:
8058:
7398:
5823:
5611:
4939:
4088:
3779:
3762:
3082:
3065:
2912:
2895:
2809:
1626:
595:
3738:
3721:
3556:
1674:
are being tested and are a possible choice of treatment for these patients.
1595:
caused a loss of GAF and ISGF3 activation but was dominant for one cellular
628:
544:
422:
10994:
10974:
10893:
10883:
10825:
10772:
10702:
10601:
10545:
10232:
10222:
10212:
10115:
10095:
10060:
10055:
9761:
9719:
9608:
8920:
8803:
8795:
8166:
8122:
7125:
6973:
4096:
4067:
4030:
3991:
3934:
3899:
3864:
3856:
3829:
3820:
3803:
3788:
3706:
3697:
3680:
3616:
3607:
3590:
3589:
Xie B, Zhao J, Kitagawa M, Durbin J, Madri JA, Guan JL, Fu XY (June 2001).
3575:
3516:
3507:
3490:
3472:
3453:
3364:
3305:
3274:
3265:
3248:
3184:
3143:
3134:
3117:
3091:
3050:
3014:
2965:
2956:
2939:
2921:
2877:
2720:
2702:
2671:
2652:
2604:
2568:
2471:
2395:
2346:
2310:
2269:
2220:
2202:
2171:
2055:
2004:
1952:
1667:
1663:
1451:
401:
180:
4111:
3942:
3747:
3665:
3413:
3323:
3233:
3215:
2828:
2769:
1420:
1415:
703:
11004:
10999:
10903:
10888:
10860:
10850:
10845:
10800:
10767:
10762:
10757:
10752:
10747:
10732:
10727:
10550:
10535:
10530:
10349:
10334:
10151:
9880:
9292:
8895:
7375:
7090:
7055:
5444:
5249:
5244:
4687:
4491:
4486:
4382:
4262:
3679:
Wong AH, Durbin JE, Li S, Dever TE, Decker T, Koromilas AE (April 2001).
2251:
2120:
2096:
1671:
1659:
1587:
1484:
1245:
1226:
4045:
2412:
Primary Immunodeficiency Diseases: Definition, Diagnosis, and Management
2143:
719:
DNA-binding transcription activator activity, RNA polymerase II-specific
10840:
10742:
10596:
10141:
9604:
9555:
9027:
8631:
8540:
8520:
8493:
7840:
7589:
7438:
7426:
7421:
6420:
6415:
5179:
5174:
5152:
5018:
4836:
4540:
4481:
4476:
4456:
1810:
300:
197:
147:
4022:
2751:
88:
84:
80:
76:
11014:
11009:
10790:
10237:
9478:
9468:
9451:
8925:
8698:
7944:
5649:
5078:
4736:
4225:
2453:
1596:
1100:
699:
DNA-binding transcription factor activity, RNA polymerase II-specific
634:
RNA polymerase II cis-regulatory region sequence-specific DNA binding
367:
354:
266:
253:
155:
3489:
Kristof AS, Marks-Konczalik J, Billings E, Moss J (September 2003).
3246:
10242:
9686:
8945:
7085:
5644:
5601:
4653:
2596:
2301:
2284:
1636:
1592:
1404:
8723:
3488:
2685:
Zhang X, Wrzeszczynska MH, Horvath CM, Darnell JE (October 1999).
2435:
1472:
STAT1 is involved in upregulating genes due to a signal by either
624:
RNA polymerase II general transcription initiation factor activity
9345:
9325:
9320:
9032:
7006:
6790:
4702:
4697:
4692:
4680:
4675:
3877:
2894:
Olayioye MA, Beuvink I, Horsch K, Daly JM, Hynes NE (June 1999).
1212:
1167:
1085:
1081:
1016:
positive regulation of nitric-oxide synthase biosynthetic process
886:
negative regulation by virus of viral protein levels in host cell
30:
2684:
1968:
135:
10815:
10805:
10450:
10446:
10442:
10438:
10434:
10430:
9526:
9521:
9516:
9506:
9501:
9220:
8775:
8770:
8765:
8760:
8026:
8021:
7898:
7893:
7888:
7873:
7864:
7859:
7854:
7833:
7747:
7742:
7530:
7525:
7505:
7500:
7490:
7485:
7323:
7275:
7270:
7265:
7260:
7230:
7225:
7220:
7215:
7185:
7135:
7130:
6893:
6813:
6785:
6780:
6775:
6770:
6765:
6760:
6755:
6750:
6745:
6740:
6735:
6730:
6725:
6720:
6715:
6710:
6705:
6700:
6690:
6685:
6680:
6675:
6670:
6665:
6660:
6650:
6645:
6640:
6600:
6553:
6548:
6543:
6538:
6533:
6528:
6518:
6506:
6501:
6267:
6262:
6257:
6139:
6134:
6106:
6101:
6086:
6081:
6076:
6066:
6061:
6049:
6044:
5416:
5411:
5406:
5401:
5396:
5371:
5298:
5266:
5209:
5204:
4991:
4986:
4981:
4865:
4670:
4560:
4555:
4528:
4523:
4518:
4444:
1751:
1739:
1733:
1640:
1388:
1122:
575:
4119:
3801:
2978:
2626:
Ouchi T, Lee SW, Ouchi M, Aaronson SA, Horvath CM (May 2000).
2581:
2408:
10485:
10426:
10422:
10418:
10414:
10410:
10406:
10303:
9875:
9870:
9865:
9860:
9855:
9850:
9845:
9827:
9822:
9817:
9812:
9794:
9789:
9784:
9779:
9774:
9570:
9548:
9543:
9511:
9400:
9395:
9340:
9335:
9330:
9274:
9183:
9178:
9173:
9168:
9163:
9158:
9153:
9148:
9096:
9091:
9079:
9074:
9069:
9064:
9052:
9047:
9042:
9037:
9006:
8973:
8968:
8963:
8910:
8905:
8900:
8875:
8833:
8828:
8823:
8818:
8813:
8780:
8733:
8728:
8674:
8669:
8664:
8659:
8636:
8411:
8396:
8391:
8386:
8381:
8376:
8371:
8366:
8361:
8356:
8346:
8336:
8331:
8316:
8311:
8301:
8296:
8291:
8281:
8276:
8271:
8266:
8261:
8256:
8251:
8221:
8216:
8206:
8201:
8186:
8181:
8176:
8171:
8105:
8100:
8095:
8068:
8043:
8011:
8004:
7999:
7905:
7883:
7878:
7850:
7828:
7823:
7818:
7813:
7708:
7703:
7648:
7641:
7636:
7621:
7594:
7255:
7250:
7245:
7240:
7235:
7210:
7205:
7200:
7195:
7190:
7180:
7175:
7170:
7165:
7160:
7155:
7150:
7145:
7140:
7120:
7115:
7110:
7105:
7100:
7095:
7080:
7075:
6900:
6888:
6883:
6878:
6873:
6841:
6836:
6635:
6625:
6620:
6615:
6610:
6605:
6595:
6590:
6585:
6580:
6496:
6486:
6479:
6474:
6469:
6464:
6454:
6398:
6393:
6388:
6383:
6378:
6373:
6368:
6289:
6284:
6279:
6223:
6218:
6117:
6096:
6091:
5965:
5960:
5955:
5950:
5945:
5940:
5147:
4912:
4907:
4902:
4892:
4887:
4882:
4872:
4860:
4810:
4790:
4731:
4719:
4714:
4638:
4631:
4626:
4616:
4609:
4604:
4535:
4466:
4439:
4434:
4417:
4412:
4407:
4402:
4397:
4387:
4375:
4370:
4348:
4338:
4333:
4323:
3720:
Li X, Leung S, Qureshi S, Darnell JE, Stark GR (March 1996).
3247:
Chatterjee-Kishore M, van Den Akker F, Stark GR (July 2000).
1816:
1804:
1798:
1780:
1774:
1703:
1697:
1691:
1516:
1492:
1031:
positive regulation of transcription of Notch receptor target
664:
RNA polymerase II core promoter sequence-specific DNA binding
3802:
Fagerlund R, Mélen K, Kinnunen L, Julkunen I (August 2002).
3760:
2782:
10870:
10782:
10719:
9933:
9928:
9923:
9918:
9913:
9908:
9903:
9898:
9597:
9592:
9587:
9577:
9565:
9560:
9407:
9390:
9254:
9249:
9244:
9215:
9210:
9143:
9138:
9133:
9128:
9123:
9118:
9113:
9108:
9059:
8953:
8915:
8890:
8885:
8880:
8863:
8755:
8748:
8743:
8624:
8619:
8614:
8609:
8604:
8599:
8594:
8589:
8579:
8572:
8562:
8557:
8545:
8535:
8530:
8513:
8508:
8503:
8486:
8481:
8476:
8451:
8446:
8441:
8159:
8154:
8149:
8144:
8139:
8078:
8053:
8048:
7989:
7984:
7979:
7974:
7969:
7964:
7959:
7954:
7949:
7920:
7915:
7808:
7803:
7798:
7793:
7779:
7774:
7769:
7764:
7759:
7730:
7725:
7720:
7686:
7681:
7676:
7671:
7666:
7661:
7626:
7614:
7609:
7604:
7557:
7552:
7547:
7542:
7537:
7458:
7443:
7433:
7409:
7404:
7390:
7385:
7380:
7370:
7365:
7353:
7348:
7292:
7287:
7065:
7050:
7045:
7033:
7028:
6861:
6856:
6851:
6695:
6630:
6575:
6570:
6565:
6449:
6444:
6439:
6363:
6358:
6353:
6348:
6343:
6338:
6333:
6328:
6323:
6306:
6301:
6245:
6240:
6208:
6203:
6198:
6188:
6183:
6176:
6171:
6166:
6161:
6151:
6146:
6129:
5987:
5982:
5977:
5905:
5366:
5361:
5356:
5351:
5346:
5341:
5254:
5239:
5216:
5189:
5162:
5157:
5122:
5100:
5095:
5090:
5073:
5068:
5058:
5048:
4998:
4956:
4951:
4934:
4929:
4924:
4822:
4817:
4805:
4763:
4758:
4748:
4663:
4658:
4648:
4567:
4550:
4513:
4501:
4496:
4471:
4429:
4358:
4353:
4328:
4311:
4306:
4301:
4296:
4291:
4281:
3288:
Horvath CM, Stark GR, Kerr IM, Darnell JE (December 1996).
2531:
2233:
2185:
Zhang Y, Chen Y, Yun H, Liu Z, Su M, Lai R (October 2017).
1786:
1762:
1745:
1447:
3336:
3115:
3063:
861:
regulation of type I interferon-mediated signaling pathway
846:
negative regulation of I-kappaB kinase/NF-kappaB signaling
9239:
8868:
8858:
8738:
8134:
7691:
7040:
6491:
6228:
5722:
5194:
5023:
5013:
5008:
4800:
4795:
3156:
3027:
2893:
1491:
stimulation, STAT1 forms homodimers or heterodimers with
901:
positive regulation of transcription by RNA polymerase II
866:
regulation of interferon-gamma-mediated signaling pathway
831:
negative regulation of transcription by RNA polymerase II
3920:
2438:"A partial form of recessive STAT1 deficiency in humans"
2409:
Rezaei N, Aghamohammadi A, Notarangelo LD (2016-11-30).
931:
positive regulation of defense response to virus by host
391:
10111:
Methoxy polyethylene glycol-epoetin beta (CERA/Mircera)
5440:
3287:
2359:
1006:
positive regulation of smooth muscle cell proliferation
2070:"IRF9 Gene - GeneCards | IRF9 Protein | IRF9 Antibody"
3719:
3588:
2625:
2017:
1914:
871:
positive regulation of mesenchymal cell proliferation
856:
negative regulation of endothelial cell proliferation
556:
3956:
Wang Y, Wu TR, Cai S, Welte T, Chin YE (July 2000).
3377:
971:
positive regulation of cell population proliferation
9369:
4008:
3923:
Biochemical and Biophysical Research Communications
3845:
Biochemical and Biophysical Research Communications
941:
positive regulation of transcription, DNA-templated
3629:
2937:
2733:
1858:
1856:
1854:
1837:
1835:
1833:
1433:Signal transducer and activator of transcription 1
936:positive regulation of interferon-alpha production
916:positive regulation of erythrocyte differentiation
3678:
3426:
1511:equence) promoter element; in response to either
338:
237:
11031:
10203:Granulocyte macrophage colony-stimulating factor
9978:
6940:
4074:
3197:
2841:
826:tumor necrosis factor-mediated signaling pathway
811:regulation of transcription by RNA polymerase II
3484:
3482:
3198:Li X, Leung S, Kerr IM, Stark GR (April 1997).
3111:
3109:
2933:
2931:
2889:
2887:
2285:"Viruses and interferon: a fight for supremacy"
2184:
1851:
1830:
9669:
3955:
1863:GRCm38: Ensembl release 89: ENSMUSG00000026104
16:Transcription factor and coding gene in humans
9964:
9655:
9630:transcription factor/coregulator deficiencies
8701:β-Scaffold factors with minor groove contacts
4211:
4135:
2734:Deberry C, Mou S, Linnekin D (October 1997).
4170:: TYROSINE PHOSPHORYLATED STAT-1/DNA COMPLEX
3949:
3871:
3836:
3795:
3754:
3672:
3582:
3523:
3479:
3427:DaFonseca CJ, Shu F, Zhang JJ (March 2001).
3420:
3330:
3240:
3150:
3106:
3057:
3021:
2972:
2928:
2884:
2835:
2678:
2619:
2331:
1515:stimulation, STAT1 forms a heterodimer with
1026:cellular response to organic cyclic compound
911:macrophage derived foam cell differentiation
821:metanephric mesenchymal cell differentiation
3914:
3713:
3623:
3529:
3371:
3281:
3191:
2842:Vidal M, Ramana CV, Dusso AS (April 2002).
2776:
2727:
2282:
1842:GRCh38: Ensembl release 89: ENSG00000115415
1071:regulation of cell population proliferation
951:interferon-gamma-mediated signaling pathway
10970:Leukemia/leukocyte inhibitory factor (LIF)
9971:
9957:
9662:
9648:
4218:
4204:
4142:
4128:
3842:
801:regulation of transcription, DNA-templated
10965:FMS-like tyrosine kinase 3 ligand (FLT3L)
10394:Interferon alpha (interferon alfa, IFN-α)
3981:
3819:
3778:
3737:
3696:
3655:
3606:
3565:
3555:
3506:
3462:
3452:
3403:
3354:
3313:
3264:
3223:
3174:
3133:
3081:
3004:
2955:
2911:
2867:
2818:
2808:
2759:
2710:
2661:
2651:
2558:
2461:
2385:
2300:
2283:Katze MG, He Y, Gale M (September 2002).
2259:
2210:
2161:
2091:
2089:
2045:
2035:
1994:
1942:
1932:
1056:interleukin-35-mediated signaling pathway
1051:interleukin-27-mediated signaling pathway
1041:interleukin-21-mediated signaling pathway
619:DNA-binding transcription factor activity
10987:Additional cytokine receptor modulators:
1591:unexplained mycobacterial disease. This
1558:Expression of STAT1 can be induced with
1061:interleukin-9-mediated signaling pathway
1046:interleukin-6-mediated signaling pathway
1728:Fanconi anemia, complementation group C
956:receptor signaling pathway via JAK-STAT
11032:
10811:Cucurbitacin I (elatericin B, JSI-124)
3892:10.1034/j.1600-0609.2001.t01-1-00385.x
2086:
1757:Interleukin 27 receptor, alpha subunit
1021:cellular response to cytokine stimulus
654:tumor necrosis factor receptor binding
10147:Granulocyte colony-stimulating factor
9952:
9643:
9368:
8697:
6939:
5439:
4242:
4241:
4199:
4185:: Structure of Unphosphorylated STAT1
4123:
2442:The Journal of Clinical Investigation
1565:
986:cellular response to insulin stimulus
926:cellular response to interferon-gamma
684:ubiquitin-like protein ligase binding
343:
304:
299:
242:
201:
196:
10506:Interferon kappa (IFN-ε/κ/τ/ζ, IFNK)
10279:Macrophage colony-stimulating factor
1964:
1962:
806:cellular response to interferon-beta
10980:Thymic stromal lymphopoietin (TSLP)
5384:(1.6) Basic helix-span-helix (bHSH)
3808:The Journal of Biological Chemistry
3767:The Journal of Biological Chemistry
3726:The Journal of Biological Chemistry
3685:The Journal of Biological Chemistry
3595:The Journal of Biological Chemistry
3495:The Journal of Biological Chemistry
3253:The Journal of Biological Chemistry
3122:The Journal of Biological Chemistry
2944:The Journal of Biological Chemistry
2900:The Journal of Biological Chemistry
1603:
1574:
1036:cytokine-mediated signaling pathway
981:response to organic cyclic compound
921:type I interferon signaling pathway
881:negative regulation of angiogenesis
689:promoter-specific chromatin binding
13:
4001:
3530:Liao J, Fu Y, Shuai K (May 2000).
2366:American Journal of Human Genetics
1443:which in humans is encoded by the
14:
11076:
4105:
1959:
1649:autoimmune polyendocrine syndrome
674:histone acetyltransferase binding
614:protein homodimerization activity
4175:
4160:
3974:10.1128/mcb.20.13.4505-4512.2000
2997:10.1128/mcb.20.13.4724-4735.2000
2335:Cancer Genomics & Proteomics
1722:Epidermal growth factor receptor
565:
327:
320:
314:
291:
226:
219:
213:
188:
29:
10511:Interferon omega (IFN-ω, IFNW1)
9371:(0) Other transcription factors
8655:transcriptional enhancer factor
4272:Activating transcription factor
4149:
3880:European Journal of Haematology
2860:10.1128/mcb.22.8.2777-2787.2002
2575:
2525:
2516:
2507:
2478:
2429:
2402:
2353:
2325:
2276:
2227:
2178:
2137:
2113:
1677:
1639:, cytopenia, regression of the
976:response to mechanical stimulus
791:regulation of apoptotic process
750:perinuclear region of cytoplasm
709:CCR5 chemokine receptor binding
3962:Molecular and Cellular Biology
3294:Molecular and Cellular Biology
3204:Molecular and Cellular Biology
2985:Molecular and Cellular Biology
2848:Molecular and Cellular Biology
2691:Molecular and Cellular Biology
2240:Molecular and Cellular Biology
2062:
2011:
1975:Journal of Clinical Immunology
1908:
1890:
1872:
714:protein phosphatase 2A binding
576:More reference expression data
545:More reference expression data
1:
8585:Interferon regulatory factors
6824:(2.5) Alternating composition
6020:General transcription factors
4060:10.1016/S0378-1119(02)00398-0
3043:10.1016/s0014-4827(03)00261-1
2074:GeneCards Human Gene Database
1824:
1769:Mammalian target of rapamycin
996:response to hydrogen peroxide
694:sequence-specific DNA binding
312:
211:
7870:Octamer transcription factor
4578:(1.2) Basic helix-loop-helix
3356:10.4049/jimmunol.170.10.4886
2551:10.1182/blood-2015-11-679902
1645:systemic lupus erythematosus
851:transcription, DNA-templated
7:
11040:Genes on human chromosome 2
10355:Thrombopoietin (THPO, MGDF)
10121:Pegol sihematide (EPO-018B)
10041:Carbamylated erythropoietin
4644:Myogenic regulatory factors
3176:10.4049/jimmunol.171.6.2989
1457:
1001:response to peptide hormone
841:response to interferon-beta
659:double-stranded DNA binding
527:subcutaneous adipose tissue
10:
11081:
9671:JAK-STAT signaling pathway
3031:Experimental Cell Research
2378:10.1016/j.ajhg.2015.11.014
2289:Nature Reviews. Immunology
2163:10.1182/blood-2003-10-3508
1632:Mycobacterium tuberculosis
896:endothelial cell migration
775:protein-containing complex
629:signal transducer activity
10949:
10927:
10904:Tofacitinib (tasocitinib)
10869:
10861:Tofacitinib (tasocitinib)
10781:
10768:Tofacitinib (tasocitinib)
10718:
10701:
10694:
10674:
10654:
10634:
10610:
10569:
10376:
10367:
10322:
10302:
10251:
10185:
10129:
10018:
10009:
9989:
9889:
9836:
9803:
9760:
9751:
9718:
9710:Type II cytokine receptor
9695:
9677:
9625:
9487:
9447:
9416:
9381:
9377:
9364:
9306:
9283:
9265:
9015:
8989:
8941:
8844:
8791:
8711:
8707:
8693:
8645:
8464:(3.5) Tryptophan clusters
8462:
8422:
8118:
7935:
7575:
7301:
6989:
6970:
6958:
6954:
6935:
6909:
6822:
6801:
6003:
5923:
5894:
5874:
5849:
5812:
5731:
5627:
5475:
5456:
5452:
5435:
5382:
5327:
5225:
5135:
5111:
5034:
4967:
4831:
4781:
4590:
4576:
4254:
4250:
4237:
4155:
2583:human STAT1 deficiency".
2037:10.3389/fonc.2023.1180642
1987:10.1007/s10875-016-0312-3
1934:10.3389/fonc.2023.1180642
1898:"Mouse PubMed Reference:"
1880:"Human PubMed Reference:"
1419:
1414:
1410:
1403:
1387:
1374:Chr 2: 190.91 – 191.02 Mb
1368:
1355:
1351:
1330:
1326:
1319:
1292:
1288:
1267:
1263:
1256:
1243:
1239:
1224:
1220:
1211:
1198:
1194:
1179:
1175:
1166:
1153:
1149:
1134:
1130:
1121:
1106:
1099:
1095:
1079:
946:defense response to virus
644:identical protein binding
594:
590:
573:
564:
555:
542:
491:
482:
433:epithelium of nasopharynx
429:
420:
390:
382:
378:
361:
348:
311:
290:
281:
277:
260:
247:
210:
187:
178:
174:
129:
126:
116:
109:
104:
73:
68:
51:
46:
41:
37:
28:
23:
10582:Interferon gamma (IFN-γ)
9705:Type I cytokine receptor
9285:(4.10) Cold-shock domain
4089:10.2174/1570162052773013
3780:10.1074/jbc.274.34.24059
3396:10.1093/emboj/17.23.6963
3083:10.1182/blood.v98.5.1392
2913:10.1074/jbc.274.24.17209
2810:10.1073/pnas.93.26.15092
2191:Cell Death & Disease
1682:STAT1 has been shown to
1562:, a compound in garlic.
1450:. It is a member of the
836:renal tubule development
10482:Interferon beta (IFN-β)
4231:intracellular receptors
3739:10.1074/jbc.271.10.5790
3648:10.1093/emboj/16.6.1291
3557:10.1073/pnas.97.10.5267
2740:The Biochemical Journal
10960:Cardiotrophin 1 (CT-1)
3935:10.1006/bbrc.1997.7493
3857:10.1006/bbrc.2001.5759
3821:10.1074/jbc.M202943200
3698:10.1074/jbc.M011240200
3608:10.1074/jbc.M009063200
3508:10.1074/jbc.M301053200
3454:10.1073/pnas.061487598
3306:10.1128/mcb.16.12.6957
3266:10.1074/jbc.M001861200
3135:10.1074/jbc.M100087200
2957:10.1074/jbc.M202823200
2703:10.1128/MCB.19.10.7138
2653:10.1073/pnas.080469697
2203:10.1038/cddis.2017.481
1381:Chr 1: 52.16 – 52.2 Mb
531:mucous cell of stomach
507:mesenteric lymph nodes
469:metanephric glomerulus
345:1 C1.1|1 26.81 cM
11060:Transcription factors
10957:Additional cytokines:
10884:Decernotinib (VX-509)
10521:Peginterferon alfa-2b
10516:Peginterferon alfa-2a
10036:Asialo erythropoietin
8994:TATA-binding proteins
4227:Transcription factors
3343:Journal of Immunology
3216:10.1128/mcb.17.4.2048
3163:Journal of Immunology
2024:Frontiers in Oncology
1921:Frontiers in Oncology
1622:Staphylococcus aureus
10472:Interferon alfacon-1
10101:Erythropoietin (EPO)
4077:Current HIV Research
2252:10.1128/mcb.00295-14
2125:www.ncbi.nlm.nih.gov
1710:CREB-binding protein
1441:transcription factor
991:response to cytokine
961:response to nutrient
306:Chromosome 1 (mouse)
204:Chromosome 2 (human)
69:List of PDB id codes
42:Available structures
11065:Signal transduction
10619:See IL-28R (IFNLR)
10587:Interferon gamma 1b
10477:Interferon alpha-n3
9489:(0.6) Miscellaneous
9020:High-mobility group
8716:Rel homology region
5706:Testicular receptor
5447:DNA-binding domains
3548:2000PNAS...97.5267L
3445:2001PNAS...98.3034D
2801:1996PNAS...9315092Z
2644:2000PNAS...97.5208O
1716:Calcitriol receptor
906:signal transduction
515:submandibular gland
10975:Oncostatin M (OSM)
10501:Interferon beta 1b
10496:Interferon beta 1a
10467:Interferon alfa n1
10462:Interferon alfa 2b
10457:Interferon alfa 2a
10291:Kinase inhibitors:
8854:p53 p63 p73 family
8427:Heat shock factors
1566:Mutations of STAT1
1519:that can bind the
1487:. In response to
1467:Type I interferons
1201:ENSMUSG00000026104
784:Biological process
728:Cellular component
602:Molecular function
523:epithelium of lens
11027:
11026:
11023:
11022:
10945:
10944:
10712:
10630:
10629:
10363:
10362:
10106:Erythropoietin-Fc
9980:Cytokine receptor
9946:
9945:
9942:
9941:
9697:Cytokine receptor
9637:
9636:
9621:
9620:
9617:
9616:
9360:
9359:
9356:
9355:
8689:
8688:
8685:
8684:
7931:
7930:
7571:
7570:
6931:
6930:
6927:
6926:
5919:
5918:
5775:Mineralocorticoid
5431:
5430:
5427:
5426:
5131:
5130:
4244:(1) Basic domains
4193:
4192:
4023:10.1159/000053968
2752:10.1042/bj3270073
2246:(12): 2235–2248.
1560:diallyl disulfide
1495:that bind to the
1430:
1429:
1426:
1425:
1399:
1398:
1364:
1363:
1345:
1344:
1315:
1314:
1282:
1281:
1252:
1251:
1233:
1232:
1207:
1206:
1188:
1187:
1162:
1161:
1143:
1142:
1091:
1090:
966:blood circulation
586:
585:
582:
581:
551:
550:
538:
537:
476:
475:
374:
373:
273:
272:
168:STAT1 - orthologs
100:
99:
96:
95:
52:Ortholog search:
11072:
10716:
10715:
10706:
10699:
10698:
10558:Decoy receptors:
10374:
10373:
10051:Darbepoetin alfa
10016:
10015:
9973:
9966:
9959:
9950:
9949:
9758:
9757:
9753:Adaptor proteins
9664:
9657:
9650:
9641:
9640:
9461:-related factors
9379:
9378:
9366:
9365:
9267:(4.9) Grainyhead
8709:
8708:
8695:
8694:
8647:(3.6) TEA domain
7937:(3.2) Paired box
7578:
7312:
7306:
7000:
6994:
6987:
6986:
6983:
6977:
6968:
6967:
6956:
6955:
6945:Helix-turn-helix
6937:
6936:
5899:
5879:
5854:
5817:
5787:Estrogen related
5736:
5632:
5480:
5473:
5472:
5461:Nuclear receptor
5454:
5453:
5437:
5436:
5116:
5037:
4970:
4839:
4784:
4593:
4588:
4587:
4252:
4251:
4239:
4238:
4220:
4213:
4206:
4197:
4196:
4179:
4164:
4144:
4137:
4130:
4121:
4120:
4100:
4071:
4042:
3996:
3995:
3985:
3953:
3947:
3946:
3918:
3912:
3911:
3875:
3869:
3868:
3840:
3834:
3833:
3823:
3799:
3793:
3792:
3782:
3773:(34): 24059–65.
3758:
3752:
3751:
3741:
3717:
3711:
3710:
3700:
3691:(17): 13727–37.
3676:
3670:
3669:
3659:
3636:The EMBO Journal
3627:
3621:
3620:
3610:
3601:(22): 19512–23.
3586:
3580:
3579:
3569:
3559:
3527:
3521:
3520:
3510:
3501:(36): 33637–44.
3486:
3477:
3476:
3466:
3456:
3424:
3418:
3417:
3407:
3384:The EMBO Journal
3375:
3369:
3368:
3358:
3334:
3328:
3327:
3317:
3285:
3279:
3278:
3268:
3259:(27): 20406–11.
3244:
3238:
3237:
3227:
3195:
3189:
3188:
3178:
3154:
3148:
3147:
3137:
3128:(25): 22948–53.
3113:
3104:
3103:
3085:
3061:
3055:
3054:
3025:
3019:
3018:
3008:
2976:
2970:
2969:
2959:
2950:(34): 30716–23.
2935:
2926:
2925:
2915:
2906:(24): 17209–18.
2891:
2882:
2881:
2871:
2839:
2833:
2832:
2822:
2812:
2780:
2774:
2773:
2763:
2731:
2725:
2724:
2714:
2682:
2676:
2675:
2665:
2655:
2623:
2617:
2616:
2579:
2573:
2572:
2562:
2529:
2523:
2520:
2514:
2511:
2505:
2504:
2502:
2501:
2492:. Archived from
2482:
2476:
2475:
2465:
2454:10.1172/jci37083
2433:
2427:
2426:
2406:
2400:
2399:
2389:
2357:
2351:
2350:
2329:
2323:
2322:
2304:
2280:
2274:
2273:
2263:
2231:
2225:
2224:
2214:
2182:
2176:
2175:
2165:
2156:(8): 2475–2483.
2141:
2135:
2134:
2132:
2131:
2117:
2111:
2110:
2108:
2107:
2093:
2084:
2083:
2081:
2080:
2066:
2060:
2059:
2049:
2039:
2015:
2009:
2008:
1998:
1966:
1957:
1956:
1946:
1936:
1912:
1906:
1905:
1894:
1888:
1887:
1876:
1870:
1860:
1849:
1839:
1793:Protein kinase R
1616:Candida albicans
1604:Gain of function
1575:Loss of function
1412:
1411:
1383:
1376:
1359:
1349:
1348:
1340:
1324:
1323:
1320:RefSeq (protein)
1310:
1286:
1285:
1277:
1261:
1260:
1237:
1236:
1218:
1217:
1192:
1191:
1173:
1172:
1147:
1146:
1128:
1127:
1097:
1096:
1066:defense response
1011:response to cAMP
669:cadherin binding
592:
591:
578:
569:
562:
561:
547:
487:
485:Top expressed in
480:
479:
453:endothelial cell
441:mononuclear cell
425:
423:Top expressed in
418:
417:
397:
396:
380:
379:
370:
357:
346:
331:
324:
318:
307:
295:
279:
278:
269:
256:
245:
230:
223:
217:
206:
192:
176:
175:
170:
121:
114:
91:
66:
65:
60:
39:
38:
33:
21:
20:
11080:
11079:
11075:
11074:
11073:
11071:
11070:
11069:
11045:Gene expression
11030:
11029:
11028:
11019:
10941:
10937:Deucravacitinib
10923:
10865:
10777:
10705:
10690:
10670:
10650:
10626:
10606:
10565:
10399:Interferon alfa
10359:
10318:
10298:
10247:
10181:
10177:Pegnartograstim
10162:Lipegfilgrastim
10125:
10071:Epoetin epsilon
10005:
9985:
9977:
9947:
9938:
9885:
9832:
9799:
9747:
9714:
9691:
9673:
9668:
9638:
9633:
9613:
9483:
9443:
9412:
9373:
9352:
9302:
9279:
9261:
9011:
8985:
8937:
8840:
8787:
8703:
8681:
8641:
8458:
8418:
8114:
7927:
7576:
7567:
7308:
7307:
7302:
7297:
6996:
6995:
6990:
6979:
6978:
6971:
6950:
6923:
6905:
6818:
6806:
6797:
6012:
6008:
5999:
5928:
5925:(2.2) Other Cys
5915:
5895:
5890:
5875:
5870:
5850:
5845:
5813:
5808:
5743:Steroid hormone
5732:
5727:
5628:
5623:
5487:Thyroid hormone
5476:
5467:
5448:
5423:
5378:
5323:
5221:
5127:
5114:
5112:
5107:
5035:
5030:
4968:
4963:
4834:
4832:
4827:
4782:
4777:
4591:
4572:
4246:
4233:
4224:
4194:
4189:
4186:
4180:
4171:
4165:
4151:
4148:
4108:
4103:
4017:(5–6): 325–30.
4004:
4002:Further reading
3999:
3968:(13): 4505–12.
3954:
3950:
3919:
3915:
3876:
3872:
3841:
3837:
3814:(33): 30072–8.
3800:
3796:
3759:
3755:
3718:
3714:
3677:
3673:
3642:(6): 1291–304.
3628:
3624:
3587:
3583:
3542:(10): 5267–72.
3528:
3524:
3487:
3480:
3425:
3421:
3390:(23): 6963–71.
3376:
3372:
3349:(10): 4886–90.
3335:
3331:
3300:(12): 6957–64.
3286:
3282:
3245:
3241:
3196:
3192:
3155:
3151:
3114:
3107:
3076:(5): 1392–401.
3062:
3058:
3026:
3022:
2991:(13): 4724–35.
2977:
2973:
2936:
2929:
2892:
2885:
2840:
2836:
2795:(26): 15092–6.
2781:
2777:
2732:
2728:
2697:(10): 7138–46.
2683:
2679:
2638:(10): 5208–13.
2624:
2620:
2585:Nature Genetics
2580:
2576:
2545:(25): 3154–64.
2530:
2526:
2521:
2517:
2512:
2508:
2499:
2497:
2484:
2483:
2479:
2434:
2430:
2423:
2407:
2403:
2358:
2354:
2330:
2326:
2281:
2277:
2232:
2228:
2183:
2179:
2142:
2138:
2129:
2127:
2119:
2118:
2114:
2105:
2103:
2101:www.uniprot.org
2095:
2094:
2087:
2078:
2076:
2068:
2067:
2063:
2016:
2012:
1967:
1960:
1913:
1909:
1896:
1895:
1891:
1878:
1877:
1873:
1861:
1852:
1840:
1831:
1827:
1822:
1680:
1606:
1577:
1568:
1460:
1421:View/Edit Mouse
1416:View/Edit Human
1379:
1372:
1369:Location (UCSC)
1357:
1336:
1332:
1306:
1302:
1298:
1294:
1273:
1269:
1182:ENSG00000115415
1075:
779:
723:
679:histone binding
639:protein binding
574:
543:
534:
529:
525:
521:
517:
513:
509:
505:
501:
497:
483:
472:
467:
463:
459:
455:
451:
447:
443:
439:
435:
421:
365:
352:
344:
334:
333:
332:
325:
305:
282:Gene location (
264:
251:
243:
233:
232:
231:
224:
202:
179:Gene location (
130:
117:
110:
75:
53:
17:
12:
11:
5:
11078:
11068:
11067:
11062:
11057:
11052:
11047:
11042:
11025:
11024:
11021:
11020:
11018:
11017:
11012:
11007:
11002:
10997:
10992:
10983:
10982:
10977:
10972:
10967:
10962:
10953:
10951:
10947:
10946:
10943:
10942:
10940:
10939:
10933:
10931:
10925:
10924:
10922:
10921:
10916:
10911:
10906:
10901:
10896:
10891:
10886:
10881:
10879:Cercosporamide
10875:
10873:
10867:
10866:
10864:
10863:
10858:
10853:
10848:
10843:
10838:
10833:
10828:
10823:
10821:Deuruxolitinib
10818:
10813:
10808:
10803:
10798:
10793:
10787:
10785:
10779:
10778:
10776:
10775:
10770:
10765:
10760:
10755:
10750:
10745:
10740:
10738:Deuruxolitinib
10735:
10730:
10724:
10722:
10713:
10696:
10692:
10691:
10689:
10688:
10680:
10678:
10672:
10671:
10669:
10668:
10660:
10658:
10652:
10651:
10649:
10648:
10640:
10638:
10632:
10631:
10628:
10627:
10625:
10624:
10616:
10614:
10612:IFNLR (λ, III)
10608:
10607:
10605:
10604:
10599:
10590:
10589:
10584:
10575:
10573:
10567:
10566:
10564:
10563:
10554:
10553:
10548:
10543:
10538:
10533:
10524:
10523:
10518:
10513:
10508:
10503:
10498:
10493:
10479:
10474:
10469:
10464:
10459:
10454:
10396:
10391:
10382:
10380:
10378:IFNAR (α/β, I)
10371:
10365:
10364:
10361:
10360:
10358:
10357:
10352:
10347:
10345:Promegapoietin
10342:
10337:
10328:
10326:
10324:Thrombopoietin
10320:
10319:
10317:
10316:
10308:
10306:
10300:
10299:
10297:
10296:
10287:
10286:
10281:
10276:
10271:
10269:Interleukin-34
10266:
10257:
10255:
10249:
10248:
10246:
10245:
10240:
10235:
10226:
10225:
10220:
10215:
10210:
10205:
10200:
10191:
10189:
10183:
10182:
10180:
10179:
10174:
10169:
10164:
10159:
10154:
10149:
10144:
10135:
10133:
10127:
10126:
10124:
10123:
10118:
10113:
10108:
10103:
10098:
10093:
10088:
10083:
10078:
10073:
10068:
10063:
10058:
10053:
10048:
10043:
10038:
10033:
10024:
10022:
10020:Erythropoietin
10013:
10007:
10006:
10004:
10003:
9995:
9993:
9987:
9986:
9976:
9975:
9968:
9961:
9953:
9944:
9943:
9940:
9939:
9937:
9936:
9931:
9926:
9921:
9916:
9911:
9906:
9901:
9895:
9893:
9887:
9886:
9884:
9883:
9878:
9873:
9868:
9863:
9858:
9853:
9848:
9842:
9840:
9834:
9833:
9831:
9830:
9825:
9820:
9815:
9809:
9807:
9801:
9800:
9798:
9797:
9792:
9787:
9782:
9777:
9772:
9766:
9764:
9755:
9749:
9748:
9746:
9745:
9740:
9735:
9730:
9724:
9722:
9716:
9715:
9713:
9712:
9707:
9701:
9699:
9693:
9692:
9690:
9689:
9683:
9681:
9675:
9674:
9667:
9666:
9659:
9652:
9644:
9635:
9634:
9626:
9623:
9622:
9619:
9618:
9615:
9614:
9612:
9611:
9602:
9601:
9600:
9595:
9590:
9580:
9575:
9574:
9573:
9568:
9563:
9553:
9552:
9551:
9546:
9536:
9531:
9530:
9529:
9524:
9519:
9514:
9509:
9504:
9493:
9491:
9485:
9484:
9482:
9481:
9476:
9471:
9465:
9463:
9445:
9444:
9442:
9441:
9436:
9431:
9425:
9423:
9414:
9413:
9411:
9410:
9405:
9404:
9403:
9398:
9387:
9385:
9375:
9374:
9362:
9361:
9358:
9357:
9354:
9353:
9351:
9350:
9349:
9348:
9343:
9338:
9333:
9328:
9323:
9312:
9310:
9304:
9303:
9301:
9300:
9295:
9289:
9287:
9281:
9280:
9278:
9277:
9271:
9269:
9263:
9262:
9260:
9259:
9258:
9257:
9252:
9247:
9242:
9232:
9231:
9230:
9225:
9224:
9223:
9218:
9213:
9198:
9193:
9188:
9187:
9186:
9181:
9176:
9171:
9166:
9161:
9156:
9151:
9146:
9141:
9136:
9131:
9126:
9121:
9116:
9111:
9101:
9100:
9099:
9094:
9084:
9083:
9082:
9077:
9072:
9067:
9057:
9056:
9055:
9050:
9045:
9040:
9030:
9024:
9022:
9013:
9012:
9010:
9009:
9004:
8998:
8996:
8987:
8986:
8984:
8983:
8978:
8977:
8976:
8971:
8966:
8961:
8950:
8948:
8939:
8938:
8936:
8935:
8930:
8929:
8928:
8923:
8918:
8913:
8908:
8903:
8898:
8893:
8888:
8883:
8873:
8872:
8871:
8866:
8861:
8850:
8848:
8846:(4.3) p53-like
8842:
8841:
8839:
8838:
8837:
8836:
8831:
8826:
8821:
8816:
8811:
8800:
8798:
8789:
8788:
8786:
8785:
8784:
8783:
8778:
8773:
8768:
8763:
8753:
8752:
8751:
8746:
8741:
8736:
8731:
8720:
8718:
8705:
8704:
8691:
8690:
8687:
8686:
8683:
8682:
8680:
8679:
8678:
8677:
8672:
8667:
8662:
8651:
8649:
8643:
8642:
8640:
8639:
8634:
8629:
8628:
8627:
8622:
8617:
8612:
8607:
8602:
8597:
8592:
8582:
8577:
8576:
8575:
8570:
8565:
8560:
8550:
8549:
8548:
8543:
8538:
8533:
8523:
8518:
8517:
8516:
8511:
8506:
8496:
8491:
8490:
8489:
8484:
8479:
8468:
8466:
8460:
8459:
8457:
8456:
8455:
8454:
8449:
8444:
8431:
8429:
8420:
8419:
8417:
8416:
8415:
8414:
8409:
8404:
8399:
8394:
8389:
8384:
8379:
8374:
8369:
8364:
8359:
8354:
8349:
8344:
8339:
8334:
8329:
8324:
8319:
8314:
8309:
8304:
8299:
8294:
8289:
8284:
8279:
8274:
8269:
8264:
8259:
8254:
8249:
8244:
8239:
8234:
8229:
8224:
8219:
8214:
8209:
8204:
8199:
8194:
8189:
8184:
8179:
8174:
8164:
8163:
8162:
8157:
8152:
8147:
8142:
8131:
8129:
8116:
8115:
8113:
8112:
8111:
8110:
8109:
8108:
8103:
8098:
8088:
8087:
8086:
8081:
8071:
8066:
8056:
8051:
8046:
8041:
8036:
8031:
8030:
8029:
8024:
8014:
8009:
8008:
8007:
8002:
7994:
7993:
7992:
7987:
7982:
7977:
7972:
7967:
7962:
7957:
7952:
7941:
7939:
7933:
7932:
7929:
7928:
7926:
7925:
7924:
7923:
7918:
7908:
7903:
7902:
7901:
7896:
7891:
7886:
7881:
7876:
7867:
7862:
7857:
7848:
7838:
7837:
7836:
7831:
7826:
7821:
7816:
7811:
7806:
7801:
7796:
7786:
7785:
7784:
7783:
7782:
7777:
7772:
7767:
7762:
7752:
7751:
7750:
7745:
7735:
7734:
7733:
7728:
7723:
7713:
7712:
7711:
7706:
7696:
7695:
7694:
7689:
7684:
7679:
7674:
7669:
7664:
7651:
7646:
7645:
7644:
7639:
7629:
7624:
7619:
7618:
7617:
7612:
7607:
7597:
7592:
7587:
7581:
7579:
7573:
7572:
7569:
7568:
7566:
7565:
7560:
7555:
7550:
7545:
7540:
7535:
7534:
7533:
7528:
7523:
7518:
7513:
7508:
7503:
7498:
7493:
7488:
7483:
7473:
7468:
7467:
7466:
7461:
7451:
7446:
7441:
7436:
7431:
7430:
7429:
7424:
7414:
7413:
7412:
7407:
7395:
7394:
7393:
7388:
7383:
7378:
7373:
7368:
7358:
7357:
7356:
7351:
7341:
7336:
7331:
7326:
7321:
7315:
7313:
7299:
7298:
7296:
7295:
7290:
7285:
7280:
7279:
7278:
7273:
7268:
7263:
7258:
7253:
7248:
7243:
7238:
7233:
7228:
7223:
7218:
7213:
7208:
7203:
7198:
7193:
7188:
7183:
7178:
7173:
7168:
7163:
7158:
7153:
7148:
7143:
7138:
7133:
7128:
7123:
7118:
7113:
7108:
7103:
7098:
7093:
7083:
7078:
7073:
7068:
7064:extended Hox:
7062:
7061:
7060:
7059:
7058:
7053:
7048:
7038:
7037:
7036:
7026:
7025:
7024:
7019:
7003:
7001:
6984:
6965:
6952:
6951:
6933:
6932:
6929:
6928:
6925:
6924:
6922:
6921:
6915:
6913:
6907:
6906:
6904:
6903:
6898:
6897:
6896:
6891:
6886:
6881:
6876:
6866:
6865:
6864:
6859:
6854:
6844:
6839:
6834:
6828:
6826:
6820:
6819:
6817:
6816:
6810:
6808:
6804:
6799:
6798:
6796:
6795:
6794:
6793:
6788:
6783:
6778:
6773:
6768:
6763:
6758:
6753:
6748:
6743:
6738:
6733:
6728:
6723:
6718:
6713:
6708:
6703:
6698:
6693:
6688:
6683:
6678:
6673:
6668:
6663:
6658:
6653:
6648:
6643:
6638:
6633:
6628:
6623:
6618:
6613:
6608:
6603:
6598:
6593:
6588:
6583:
6578:
6573:
6568:
6558:
6557:
6556:
6551:
6546:
6541:
6536:
6531:
6526:
6521:
6511:
6510:
6509:
6504:
6494:
6489:
6484:
6483:
6482:
6477:
6472:
6467:
6457:
6452:
6447:
6442:
6437:
6436:
6435:
6434:
6433:
6428:
6423:
6418:
6413:
6403:
6402:
6401:
6396:
6391:
6386:
6381:
6376:
6371:
6366:
6361:
6356:
6351:
6346:
6341:
6336:
6331:
6326:
6311:
6310:
6309:
6304:
6294:
6293:
6292:
6287:
6282:
6272:
6271:
6270:
6265:
6260:
6250:
6249:
6248:
6243:
6233:
6232:
6231:
6226:
6221:
6216:
6211:
6206:
6201:
6191:
6186:
6181:
6180:
6179:
6174:
6169:
6164:
6154:
6149:
6144:
6143:
6142:
6137:
6132:
6120:
6114:
6113:
6112:
6111:
6110:
6109:
6104:
6099:
6094:
6089:
6084:
6079:
6074:
6064:
6059:
6054:
6053:
6052:
6047:
6037:
6032:
6027:
6016:
6014:
6010:
6006:
6001:
6000:
5998:
5997:
5992:
5991:
5990:
5985:
5980:
5970:
5969:
5968:
5963:
5958:
5953:
5948:
5943:
5932:
5930:
5926:
5921:
5920:
5917:
5916:
5914:
5913:
5908:
5902:
5900:
5892:
5891:
5889:
5888:
5882:
5880:
5872:
5871:
5869:
5868:
5863:
5857:
5855:
5847:
5846:
5844:
5843:
5842:
5841:
5836:
5831:
5820:
5818:
5810:
5809:
5807:
5806:
5805:
5804:
5799:
5794:
5784:
5783:
5782:
5777:
5772:
5770:Glucocorticoid
5767:
5766:
5765:
5760:
5750:
5739:
5737:
5729:
5728:
5726:
5725:
5720:
5719:
5718:
5713:
5703:
5702:
5701:
5696:
5691:
5681:
5676:
5675:
5674:
5669:
5659:
5654:
5653:
5652:
5647:
5635:
5633:
5625:
5624:
5622:
5621:
5616:
5615:
5614:
5609:
5599:
5598:
5597:
5592:
5587:
5577:
5576:
5575:
5570:
5565:
5555:
5550:
5549:
5548:
5543:
5538:
5528:
5527:
5526:
5521:
5511:
5506:
5501:
5500:
5499:
5494:
5483:
5481:
5470:
5465:
5450:
5449:
5433:
5432:
5429:
5428:
5425:
5424:
5422:
5421:
5420:
5419:
5414:
5409:
5404:
5399:
5388:
5386:
5380:
5379:
5377:
5376:
5375:
5374:
5369:
5364:
5359:
5354:
5349:
5344:
5333:
5331:
5325:
5324:
5322:
5321:
5320:
5319:
5313:
5312:
5311:
5306:
5296:
5295:
5294:
5289:
5284:
5279:
5274:
5259:
5258:
5257:
5252:
5247:
5242:
5231:
5229:
5223:
5222:
5220:
5219:
5214:
5213:
5212:
5207:
5197:
5192:
5187:
5182:
5177:
5172:
5167:
5166:
5165:
5160:
5150:
5144:
5142:
5133:
5132:
5129:
5128:
5126:
5125:
5119:
5117:
5109:
5108:
5106:
5105:
5104:
5103:
5098:
5093:
5083:
5082:
5081:
5076:
5071:
5066:
5061:
5056:
5051:
5040:
5038:
5032:
5031:
5029:
5028:
5027:
5026:
5021:
5016:
5011:
5001:
4996:
4995:
4994:
4989:
4984:
4973:
4971:
4965:
4964:
4962:
4961:
4960:
4959:
4954:
4944:
4943:
4942:
4937:
4932:
4927:
4917:
4916:
4915:
4910:
4905:
4897:
4896:
4895:
4890:
4885:
4875:
4870:
4869:
4868:
4863:
4853:
4848:
4842:
4840:
4829:
4828:
4826:
4825:
4820:
4815:
4814:
4813:
4808:
4803:
4793:
4787:
4785:
4779:
4778:
4776:
4775:
4770:
4769:
4768:
4767:
4766:
4761:
4751:
4741:
4740:
4739:
4734:
4724:
4723:
4722:
4717:
4707:
4706:
4705:
4700:
4695:
4685:
4684:
4683:
4678:
4668:
4667:
4666:
4661:
4656:
4651:
4641:
4636:
4635:
4634:
4629:
4619:
4614:
4613:
4612:
4607:
4596:
4594:
4585:
4574:
4573:
4571:
4570:
4565:
4564:
4563:
4558:
4553:
4543:
4538:
4533:
4532:
4531:
4526:
4521:
4516:
4506:
4505:
4504:
4499:
4494:
4489:
4479:
4474:
4469:
4464:
4459:
4454:
4449:
4448:
4447:
4442:
4437:
4427:
4426:
4425:
4420:
4415:
4410:
4405:
4400:
4390:
4385:
4380:
4379:
4378:
4373:
4363:
4362:
4361:
4356:
4351:
4346:
4341:
4336:
4331:
4326:
4316:
4315:
4314:
4309:
4304:
4299:
4294:
4289:
4284:
4279:
4268:
4266:
4259:leucine zipper
4248:
4247:
4235:
4234:
4223:
4222:
4215:
4208:
4200:
4191:
4190:
4188:
4187:
4181:
4174:
4172:
4166:
4159:
4156:
4153:
4152:
4147:
4146:
4139:
4132:
4124:
4118:
4117:
4107:
4106:External links
4104:
4102:
4101:
4072:
4043:
4005:
4003:
4000:
3998:
3997:
3948:
3913:
3870:
3835:
3794:
3753:
3732:(10): 5790–4.
3712:
3671:
3622:
3581:
3522:
3478:
3419:
3370:
3329:
3280:
3239:
3210:(4): 2048–56.
3190:
3169:(6): 2989–94.
3149:
3105:
3056:
3020:
2971:
2927:
2883:
2854:(8): 2777–87.
2834:
2775:
2726:
2677:
2618:
2597:10.1038/ng1097
2574:
2524:
2515:
2506:
2490:www.asid.ma-gb
2477:
2448:(6): 1502–14.
2428:
2421:
2401:
2352:
2324:
2302:10.1038/nri888
2275:
2226:
2177:
2136:
2112:
2085:
2061:
2010:
1958:
1907:
1889:
1871:
1850:
1828:
1826:
1823:
1821:
1820:
1814:
1808:
1802:
1796:
1790:
1784:
1778:
1772:
1766:
1760:
1754:
1749:
1743:
1737:
1731:
1725:
1719:
1713:
1707:
1701:
1695:
1688:
1679:
1676:
1605:
1602:
1576:
1573:
1567:
1564:
1513:IFN-α or IFN-β
1459:
1456:
1428:
1427:
1424:
1423:
1418:
1408:
1407:
1401:
1400:
1397:
1396:
1394:
1392:
1385:
1384:
1377:
1370:
1366:
1365:
1362:
1361:
1353:
1352:
1346:
1343:
1342:
1328:
1327:
1321:
1317:
1316:
1313:
1312:
1290:
1289:
1283:
1280:
1279:
1265:
1264:
1258:
1254:
1253:
1250:
1249:
1241:
1240:
1234:
1231:
1230:
1222:
1221:
1215:
1209:
1208:
1205:
1204:
1196:
1195:
1189:
1186:
1185:
1177:
1176:
1170:
1164:
1163:
1160:
1159:
1151:
1150:
1144:
1141:
1140:
1132:
1131:
1125:
1119:
1118:
1113:
1108:
1104:
1103:
1093:
1092:
1089:
1088:
1077:
1076:
1074:
1073:
1068:
1063:
1058:
1053:
1048:
1043:
1038:
1033:
1028:
1023:
1018:
1013:
1008:
1003:
998:
993:
988:
983:
978:
973:
968:
963:
958:
953:
948:
943:
938:
933:
928:
923:
918:
913:
908:
903:
898:
893:
888:
883:
878:
873:
868:
863:
858:
853:
848:
843:
838:
833:
828:
823:
818:
813:
808:
803:
798:
793:
787:
785:
781:
780:
778:
777:
772:
767:
762:
757:
752:
747:
742:
737:
731:
729:
725:
724:
722:
721:
716:
711:
706:
701:
696:
691:
686:
681:
676:
671:
666:
661:
656:
651:
649:enzyme binding
646:
641:
636:
631:
626:
621:
616:
611:
605:
603:
599:
598:
588:
587:
584:
583:
580:
579:
571:
570:
559:
553:
552:
549:
548:
540:
539:
536:
535:
533:
532:
528:
524:
520:
516:
512:
508:
504:
500:
496:
492:
489:
488:
477:
474:
473:
471:
470:
466:
462:
458:
454:
450:
446:
442:
438:
434:
430:
427:
426:
414:
413:
405:
394:
388:
387:
384:RNA expression
376:
375:
372:
371:
363:
359:
358:
350:
347:
342:
336:
335:
326:
319:
313:
309:
308:
303:
297:
296:
288:
287:
275:
274:
271:
270:
262:
258:
257:
249:
246:
241:
235:
234:
225:
218:
212:
208:
207:
200:
194:
193:
185:
184:
172:
171:
128:
124:
123:
115:
107:
106:
102:
101:
98:
97:
94:
93:
71:
70:
62:
61:
50:
44:
43:
35:
34:
26:
25:
15:
9:
6:
4:
3:
2:
11077:
11066:
11063:
11061:
11058:
11056:
11053:
11051:
11050:Immune system
11048:
11046:
11043:
11041:
11038:
11037:
11035:
11016:
11013:
11011:
11008:
11006:
11003:
11001:
10998:
10996:
10993:
10991:
10988:
10985:
10984:
10981:
10978:
10976:
10973:
10971:
10968:
10966:
10963:
10961:
10958:
10955:
10954:
10952:
10948:
10938:
10935:
10934:
10932:
10930:
10926:
10920:
10917:
10915:
10912:
10910:
10907:
10905:
10902:
10900:
10897:
10895:
10892:
10890:
10887:
10885:
10882:
10880:
10877:
10876:
10874:
10872:
10868:
10862:
10859:
10857:
10854:
10852:
10849:
10847:
10844:
10842:
10839:
10837:
10834:
10832:
10829:
10827:
10824:
10822:
10819:
10817:
10814:
10812:
10809:
10807:
10804:
10802:
10799:
10797:
10794:
10792:
10789:
10788:
10786:
10784:
10780:
10774:
10771:
10769:
10766:
10764:
10761:
10759:
10756:
10754:
10751:
10749:
10746:
10744:
10741:
10739:
10736:
10734:
10731:
10729:
10726:
10725:
10723:
10721:
10717:
10714:
10710:
10704:
10700:
10697:
10693:
10686:
10682:
10681:
10679:
10677:
10673:
10666:
10662:
10661:
10659:
10657:
10653:
10646:
10642:
10641:
10639:
10637:
10633:
10622:
10618:
10617:
10615:
10613:
10609:
10603:
10600:
10598:
10595:
10592:
10591:
10588:
10585:
10583:
10580:
10577:
10576:
10574:
10572:
10571:IFNGR (γ, II)
10568:
10562:
10559:
10556:
10555:
10552:
10549:
10547:
10544:
10542:
10539:
10537:
10534:
10532:
10529:
10526:
10525:
10522:
10519:
10517:
10514:
10512:
10509:
10507:
10504:
10502:
10499:
10497:
10494:
10491:
10487:
10483:
10480:
10478:
10475:
10473:
10470:
10468:
10465:
10463:
10460:
10458:
10455:
10452:
10448:
10444:
10440:
10436:
10432:
10428:
10424:
10420:
10416:
10412:
10408:
10404:
10400:
10397:
10395:
10392:
10390:
10389:Albinterferon
10387:
10384:
10383:
10381:
10379:
10375:
10372:
10370:
10366:
10356:
10353:
10351:
10348:
10346:
10343:
10341:
10338:
10336:
10333:
10330:
10329:
10327:
10325:
10321:
10314:
10310:
10309:
10307:
10305:
10301:
10295:
10292:
10289:
10288:
10285:
10282:
10280:
10277:
10275:
10272:
10270:
10267:
10265:
10262:
10259:
10258:
10256:
10254:
10250:
10244:
10241:
10239:
10236:
10234:
10231:
10228:
10227:
10224:
10221:
10219:
10216:
10214:
10211:
10209:
10206:
10204:
10201:
10199:
10196:
10193:
10192:
10190:
10188:
10187:GM-CSF (CSF2)
10184:
10178:
10175:
10173:
10172:Pegfilgrastim
10170:
10168:
10165:
10163:
10160:
10158:
10155:
10153:
10150:
10148:
10145:
10143:
10140:
10137:
10136:
10134:
10132:
10128:
10122:
10119:
10117:
10114:
10112:
10109:
10107:
10104:
10102:
10099:
10097:
10094:
10092:
10091:Epoetin theta
10089:
10087:
10086:Epoetin omega
10084:
10082:
10081:Epoetin kappa
10079:
10077:
10076:Epoetin gamma
10074:
10072:
10069:
10067:
10066:Epoetin delta
10064:
10062:
10059:
10057:
10054:
10052:
10049:
10047:
10044:
10042:
10039:
10037:
10034:
10032:
10029:
10026:
10025:
10023:
10021:
10017:
10014:
10012:
10008:
10001:
9997:
9996:
9994:
9992:
9988:
9984:
9981:
9974:
9969:
9967:
9962:
9960:
9955:
9954:
9951:
9935:
9932:
9930:
9927:
9925:
9922:
9920:
9917:
9915:
9912:
9910:
9907:
9905:
9902:
9900:
9897:
9896:
9894:
9892:
9888:
9882:
9879:
9877:
9874:
9872:
9869:
9867:
9864:
9862:
9859:
9857:
9854:
9852:
9849:
9847:
9844:
9843:
9841:
9839:
9835:
9829:
9826:
9824:
9821:
9819:
9816:
9814:
9811:
9810:
9808:
9806:
9802:
9796:
9793:
9791:
9788:
9786:
9783:
9781:
9778:
9776:
9773:
9771:
9768:
9767:
9765:
9763:
9759:
9756:
9754:
9750:
9744:
9741:
9739:
9736:
9734:
9731:
9729:
9726:
9725:
9723:
9721:
9717:
9711:
9708:
9706:
9703:
9702:
9700:
9698:
9694:
9688:
9685:
9684:
9682:
9680:
9676:
9672:
9665:
9660:
9658:
9653:
9651:
9646:
9645:
9642:
9632:
9631:
9624:
9610:
9606:
9603:
9599:
9596:
9594:
9591:
9589:
9586:
9585:
9584:
9581:
9579:
9576:
9572:
9569:
9567:
9564:
9562:
9559:
9558:
9557:
9554:
9550:
9547:
9545:
9542:
9541:
9540:
9537:
9535:
9532:
9528:
9525:
9523:
9520:
9518:
9515:
9513:
9510:
9508:
9505:
9503:
9500:
9499:
9498:
9495:
9494:
9492:
9490:
9486:
9480:
9477:
9475:
9472:
9470:
9467:
9466:
9464:
9462:
9459:
9456:
9453:
9450:
9446:
9440:
9437:
9435:
9432:
9430:
9427:
9426:
9424:
9422:
9421:Pocket domain
9419:
9415:
9409:
9406:
9402:
9399:
9397:
9394:
9393:
9392:
9389:
9388:
9386:
9384:
9383:(0.2) HMGI(Y)
9380:
9376:
9372:
9367:
9363:
9347:
9344:
9342:
9339:
9337:
9334:
9332:
9329:
9327:
9324:
9322:
9319:
9318:
9317:
9314:
9313:
9311:
9309:
9305:
9299:
9296:
9294:
9291:
9290:
9288:
9286:
9282:
9276:
9273:
9272:
9270:
9268:
9264:
9256:
9253:
9251:
9248:
9246:
9243:
9241:
9238:
9237:
9236:
9233:
9229:
9226:
9222:
9219:
9217:
9214:
9212:
9209:
9208:
9207:
9204:
9203:
9202:
9199:
9197:
9194:
9192:
9189:
9185:
9182:
9180:
9177:
9175:
9172:
9170:
9167:
9165:
9162:
9160:
9157:
9155:
9152:
9150:
9147:
9145:
9142:
9140:
9137:
9135:
9132:
9130:
9127:
9125:
9122:
9120:
9117:
9115:
9112:
9110:
9107:
9106:
9105:
9102:
9098:
9095:
9093:
9090:
9089:
9088:
9085:
9081:
9078:
9076:
9073:
9071:
9068:
9066:
9063:
9062:
9061:
9058:
9054:
9051:
9049:
9046:
9044:
9041:
9039:
9036:
9035:
9034:
9031:
9029:
9026:
9025:
9023:
9021:
9018:
9014:
9008:
9005:
9003:
9000:
8999:
8997:
8995:
8992:
8988:
8982:
8979:
8975:
8972:
8970:
8967:
8965:
8962:
8960:
8957:
8956:
8955:
8952:
8951:
8949:
8947:
8944:
8940:
8934:
8931:
8927:
8924:
8922:
8919:
8917:
8914:
8912:
8909:
8907:
8904:
8902:
8899:
8897:
8894:
8892:
8889:
8887:
8884:
8882:
8879:
8878:
8877:
8874:
8870:
8867:
8865:
8862:
8860:
8857:
8856:
8855:
8852:
8851:
8849:
8847:
8843:
8835:
8832:
8830:
8827:
8825:
8822:
8820:
8817:
8815:
8812:
8810:
8807:
8806:
8805:
8802:
8801:
8799:
8797:
8794:
8790:
8782:
8779:
8777:
8774:
8772:
8769:
8767:
8764:
8762:
8759:
8758:
8757:
8754:
8750:
8747:
8745:
8742:
8740:
8737:
8735:
8732:
8730:
8727:
8726:
8725:
8722:
8721:
8719:
8717:
8714:
8710:
8706:
8702:
8696:
8692:
8676:
8673:
8671:
8668:
8666:
8663:
8661:
8658:
8657:
8656:
8653:
8652:
8650:
8648:
8644:
8638:
8635:
8633:
8630:
8626:
8623:
8621:
8618:
8616:
8613:
8611:
8608:
8606:
8603:
8601:
8598:
8596:
8593:
8591:
8588:
8587:
8586:
8583:
8581:
8578:
8574:
8571:
8569:
8566:
8564:
8561:
8559:
8556:
8555:
8554:
8551:
8547:
8544:
8542:
8539:
8537:
8534:
8532:
8529:
8528:
8527:
8524:
8522:
8519:
8515:
8512:
8510:
8507:
8505:
8502:
8501:
8500:
8497:
8495:
8492:
8488:
8485:
8483:
8480:
8478:
8475:
8474:
8473:
8470:
8469:
8467:
8465:
8461:
8453:
8450:
8448:
8445:
8443:
8440:
8439:
8438:
8437:
8433:
8432:
8430:
8428:
8425:
8421:
8413:
8410:
8408:
8405:
8403:
8400:
8398:
8395:
8393:
8390:
8388:
8385:
8383:
8380:
8378:
8375:
8373:
8370:
8368:
8365:
8363:
8360:
8358:
8355:
8353:
8350:
8348:
8345:
8343:
8340:
8338:
8335:
8333:
8330:
8328:
8325:
8323:
8320:
8318:
8315:
8313:
8310:
8308:
8305:
8303:
8300:
8298:
8295:
8293:
8290:
8288:
8285:
8283:
8280:
8278:
8275:
8273:
8270:
8268:
8265:
8263:
8260:
8258:
8255:
8253:
8250:
8248:
8245:
8243:
8240:
8238:
8235:
8233:
8230:
8228:
8225:
8223:
8220:
8218:
8215:
8213:
8210:
8208:
8205:
8203:
8200:
8198:
8195:
8193:
8190:
8188:
8185:
8183:
8180:
8178:
8175:
8173:
8170:
8169:
8168:
8165:
8161:
8158:
8156:
8153:
8151:
8148:
8146:
8143:
8141:
8138:
8137:
8136:
8133:
8132:
8130:
8128:
8124:
8121:
8117:
8107:
8104:
8102:
8099:
8097:
8094:
8093:
8092:
8089:
8085:
8082:
8080:
8077:
8076:
8075:
8072:
8070:
8067:
8065:
8062:
8061:
8060:
8057:
8055:
8052:
8050:
8047:
8045:
8042:
8040:
8037:
8035:
8032:
8028:
8025:
8023:
8020:
8019:
8018:
8015:
8013:
8010:
8006:
8003:
8001:
7998:
7997:
7995:
7991:
7988:
7986:
7983:
7981:
7978:
7976:
7973:
7971:
7968:
7966:
7963:
7961:
7958:
7956:
7953:
7951:
7948:
7947:
7946:
7943:
7942:
7940:
7938:
7934:
7922:
7919:
7917:
7914:
7913:
7912:
7909:
7907:
7904:
7900:
7897:
7895:
7892:
7890:
7887:
7885:
7882:
7880:
7877:
7875:
7871:
7868:
7866:
7863:
7861:
7858:
7856:
7852:
7849:
7847:
7844:
7843:
7842:
7839:
7835:
7832:
7830:
7827:
7825:
7822:
7820:
7817:
7815:
7812:
7810:
7807:
7805:
7802:
7800:
7797:
7795:
7792:
7791:
7790:
7787:
7781:
7778:
7776:
7773:
7771:
7768:
7766:
7763:
7761:
7758:
7757:
7756:
7753:
7749:
7746:
7744:
7741:
7740:
7739:
7736:
7732:
7729:
7727:
7724:
7722:
7719:
7718:
7717:
7714:
7710:
7707:
7705:
7702:
7701:
7700:
7697:
7693:
7690:
7688:
7685:
7683:
7680:
7678:
7675:
7673:
7670:
7668:
7665:
7663:
7660:
7659:
7658:
7655:
7654:
7652:
7650:
7647:
7643:
7640:
7638:
7635:
7634:
7633:
7630:
7628:
7625:
7623:
7620:
7616:
7613:
7611:
7608:
7606:
7603:
7602:
7601:
7598:
7596:
7593:
7591:
7588:
7586:
7583:
7582:
7580:
7574:
7564:
7561:
7559:
7556:
7554:
7551:
7549:
7546:
7544:
7541:
7539:
7536:
7532:
7529:
7527:
7524:
7522:
7519:
7517:
7514:
7512:
7509:
7507:
7504:
7502:
7499:
7497:
7494:
7492:
7489:
7487:
7484:
7482:
7479:
7478:
7477:
7474:
7472:
7469:
7465:
7462:
7460:
7457:
7456:
7455:
7452:
7450:
7447:
7445:
7442:
7440:
7437:
7435:
7432:
7428:
7425:
7423:
7420:
7419:
7418:
7415:
7411:
7408:
7406:
7403:
7402:
7401:
7400:
7396:
7392:
7389:
7387:
7384:
7382:
7379:
7377:
7374:
7372:
7369:
7367:
7364:
7363:
7362:
7359:
7355:
7352:
7350:
7347:
7346:
7345:
7342:
7340:
7337:
7335:
7332:
7330:
7327:
7325:
7322:
7320:
7317:
7316:
7314:
7311:
7305:
7300:
7294:
7291:
7289:
7286:
7284:
7281:
7277:
7274:
7272:
7269:
7267:
7264:
7262:
7259:
7257:
7254:
7252:
7249:
7247:
7244:
7242:
7239:
7237:
7234:
7232:
7229:
7227:
7224:
7222:
7219:
7217:
7214:
7212:
7209:
7207:
7204:
7202:
7199:
7197:
7194:
7192:
7189:
7187:
7184:
7182:
7179:
7177:
7174:
7172:
7169:
7167:
7164:
7162:
7159:
7157:
7154:
7152:
7149:
7147:
7144:
7142:
7139:
7137:
7134:
7132:
7129:
7127:
7124:
7122:
7119:
7117:
7114:
7112:
7109:
7107:
7104:
7102:
7099:
7097:
7094:
7092:
7089:
7088:
7087:
7084:
7082:
7079:
7077:
7074:
7072:
7069:
7067:
7063:
7057:
7054:
7052:
7049:
7047:
7044:
7043:
7042:
7039:
7035:
7032:
7031:
7030:
7027:
7023:
7020:
7018:
7015:
7014:
7013:
7010:
7009:
7008:
7005:
7004:
7002:
6999:
6993:
6988:
6985:
6982:
6976:
6975:
6969:
6966:
6964:
6961:
6957:
6953:
6949:
6946:
6943:
6938:
6934:
6920:
6917:
6916:
6914:
6912:
6908:
6902:
6899:
6895:
6892:
6890:
6887:
6885:
6882:
6880:
6877:
6875:
6872:
6871:
6870:
6867:
6863:
6860:
6858:
6855:
6853:
6850:
6849:
6848:
6845:
6843:
6840:
6838:
6835:
6833:
6830:
6829:
6827:
6825:
6821:
6815:
6812:
6811:
6809:
6807:
6800:
6792:
6789:
6787:
6784:
6782:
6779:
6777:
6774:
6772:
6769:
6767:
6764:
6762:
6759:
6757:
6754:
6752:
6749:
6747:
6744:
6742:
6739:
6737:
6734:
6732:
6729:
6727:
6724:
6722:
6719:
6717:
6714:
6712:
6709:
6707:
6704:
6702:
6699:
6697:
6694:
6692:
6689:
6687:
6684:
6682:
6679:
6677:
6674:
6672:
6669:
6667:
6664:
6662:
6659:
6657:
6654:
6652:
6649:
6647:
6644:
6642:
6639:
6637:
6634:
6632:
6629:
6627:
6624:
6622:
6619:
6617:
6614:
6612:
6609:
6607:
6604:
6602:
6599:
6597:
6594:
6592:
6589:
6587:
6584:
6582:
6579:
6577:
6574:
6572:
6569:
6567:
6564:
6563:
6562:
6559:
6555:
6552:
6550:
6547:
6545:
6542:
6540:
6537:
6535:
6532:
6530:
6527:
6525:
6522:
6520:
6517:
6516:
6515:
6512:
6508:
6505:
6503:
6500:
6499:
6498:
6495:
6493:
6490:
6488:
6485:
6481:
6478:
6476:
6473:
6471:
6468:
6466:
6463:
6462:
6461:
6458:
6456:
6453:
6451:
6448:
6446:
6443:
6441:
6438:
6432:
6429:
6427:
6424:
6422:
6419:
6417:
6414:
6412:
6409:
6408:
6407:
6404:
6400:
6397:
6395:
6392:
6390:
6387:
6385:
6382:
6380:
6377:
6375:
6372:
6370:
6367:
6365:
6362:
6360:
6357:
6355:
6352:
6350:
6347:
6345:
6342:
6340:
6337:
6335:
6332:
6330:
6327:
6325:
6322:
6321:
6320:
6317:
6316:
6315:
6314:Sp/KLF family
6312:
6308:
6305:
6303:
6300:
6299:
6298:
6295:
6291:
6288:
6286:
6283:
6281:
6278:
6277:
6276:
6273:
6269:
6266:
6264:
6261:
6259:
6256:
6255:
6254:
6251:
6247:
6244:
6242:
6239:
6238:
6237:
6234:
6230:
6227:
6225:
6222:
6220:
6217:
6215:
6212:
6210:
6207:
6205:
6202:
6200:
6197:
6196:
6195:
6192:
6190:
6187:
6185:
6182:
6178:
6175:
6173:
6170:
6168:
6165:
6163:
6160:
6159:
6158:
6155:
6153:
6150:
6148:
6145:
6141:
6138:
6136:
6133:
6131:
6128:
6127:
6126:
6125:
6121:
6119:
6116:
6115:
6108:
6105:
6103:
6100:
6098:
6095:
6093:
6090:
6088:
6085:
6083:
6080:
6078:
6075:
6073:
6070:
6069:
6068:
6065:
6063:
6060:
6058:
6055:
6051:
6048:
6046:
6043:
6042:
6041:
6038:
6036:
6033:
6031:
6028:
6026:
6023:
6022:
6021:
6018:
6017:
6015:
6013:
6002:
5996:
5993:
5989:
5986:
5984:
5981:
5979:
5976:
5975:
5974:
5971:
5967:
5964:
5962:
5959:
5957:
5954:
5952:
5949:
5947:
5944:
5942:
5939:
5938:
5937:
5934:
5933:
5931:
5929:
5922:
5912:
5909:
5907:
5904:
5903:
5901:
5898:
5893:
5887:
5884:
5883:
5881:
5878:
5873:
5867:
5864:
5862:
5859:
5858:
5856:
5853:
5848:
5840:
5837:
5835:
5832:
5830:
5827:
5826:
5825:
5822:
5821:
5819:
5816:
5811:
5803:
5800:
5798:
5795:
5793:
5790:
5789:
5788:
5785:
5781:
5778:
5776:
5773:
5771:
5768:
5764:
5761:
5759:
5756:
5755:
5754:
5751:
5749:
5746:
5745:
5744:
5741:
5740:
5738:
5735:
5730:
5724:
5721:
5717:
5714:
5712:
5709:
5708:
5707:
5704:
5700:
5697:
5695:
5692:
5690:
5687:
5686:
5685:
5682:
5680:
5677:
5673:
5670:
5668:
5665:
5664:
5663:
5660:
5658:
5655:
5651:
5648:
5646:
5642:
5641:
5640:
5637:
5636:
5634:
5631:
5626:
5620:
5617:
5613:
5610:
5608:
5605:
5604:
5603:
5600:
5596:
5593:
5591:
5588:
5586:
5583:
5582:
5581:
5578:
5574:
5571:
5569:
5566:
5564:
5561:
5560:
5559:
5556:
5554:
5551:
5547:
5544:
5542:
5539:
5537:
5534:
5533:
5532:
5529:
5525:
5522:
5520:
5517:
5516:
5515:
5512:
5510:
5507:
5505:
5502:
5498:
5495:
5493:
5490:
5489:
5488:
5485:
5484:
5482:
5479:
5474:
5471:
5469:
5462:
5459:
5455:
5451:
5446:
5443:
5438:
5434:
5418:
5415:
5413:
5410:
5408:
5405:
5403:
5400:
5398:
5395:
5394:
5393:
5390:
5389:
5387:
5385:
5381:
5373:
5370:
5368:
5365:
5363:
5360:
5358:
5355:
5353:
5350:
5348:
5345:
5343:
5340:
5339:
5338:
5335:
5334:
5332:
5330:
5326:
5317:
5314:
5310:
5307:
5305:
5302:
5301:
5300:
5297:
5293:
5290:
5288:
5285:
5283:
5280:
5278:
5275:
5273:
5270:
5269:
5268:
5265:
5264:
5263:
5260:
5256:
5253:
5251:
5248:
5246:
5243:
5241:
5238:
5237:
5236:
5233:
5232:
5230:
5228:
5224:
5218:
5215:
5211:
5208:
5206:
5203:
5202:
5201:
5198:
5196:
5193:
5191:
5188:
5186:
5183:
5181:
5178:
5176:
5173:
5171:
5168:
5164:
5161:
5159:
5156:
5155:
5154:
5151:
5149:
5146:
5145:
5143:
5141:
5138:
5134:
5124:
5121:
5120:
5118:
5110:
5102:
5099:
5097:
5094:
5092:
5089:
5088:
5087:
5084:
5080:
5077:
5075:
5072:
5070:
5067:
5065:
5062:
5060:
5057:
5055:
5052:
5050:
5047:
5046:
5045:
5042:
5041:
5039:
5033:
5025:
5022:
5020:
5017:
5015:
5012:
5010:
5007:
5006:
5005:
5002:
5000:
4997:
4993:
4990:
4988:
4985:
4983:
4980:
4979:
4978:
4975:
4974:
4972:
4966:
4958:
4955:
4953:
4950:
4949:
4948:
4945:
4941:
4938:
4936:
4933:
4931:
4928:
4926:
4923:
4922:
4921:
4918:
4914:
4911:
4909:
4906:
4904:
4901:
4900:
4898:
4894:
4891:
4889:
4886:
4884:
4881:
4880:
4879:
4876:
4874:
4871:
4867:
4864:
4862:
4859:
4858:
4857:
4854:
4852:
4849:
4847:
4844:
4843:
4841:
4838:
4830:
4824:
4821:
4819:
4816:
4812:
4809:
4807:
4804:
4802:
4799:
4798:
4797:
4794:
4792:
4789:
4788:
4786:
4780:
4774:
4771:
4765:
4762:
4760:
4757:
4756:
4755:
4752:
4750:
4747:
4746:
4745:
4742:
4738:
4735:
4733:
4730:
4729:
4728:
4725:
4721:
4718:
4716:
4713:
4712:
4711:
4708:
4704:
4701:
4699:
4696:
4694:
4691:
4690:
4689:
4686:
4682:
4679:
4677:
4674:
4673:
4672:
4669:
4665:
4662:
4660:
4657:
4655:
4652:
4650:
4647:
4646:
4645:
4642:
4640:
4637:
4633:
4630:
4628:
4625:
4624:
4623:
4620:
4618:
4615:
4611:
4608:
4606:
4603:
4602:
4601:
4598:
4597:
4595:
4589:
4586:
4583:
4579:
4575:
4569:
4566:
4562:
4559:
4557:
4554:
4552:
4549:
4548:
4547:
4544:
4542:
4539:
4537:
4534:
4530:
4527:
4525:
4522:
4520:
4517:
4515:
4512:
4511:
4510:
4507:
4503:
4500:
4498:
4495:
4493:
4490:
4488:
4485:
4484:
4483:
4480:
4478:
4475:
4473:
4470:
4468:
4465:
4463:
4460:
4458:
4455:
4453:
4450:
4446:
4443:
4441:
4438:
4436:
4433:
4432:
4431:
4428:
4424:
4421:
4419:
4416:
4414:
4411:
4409:
4406:
4404:
4401:
4399:
4396:
4395:
4394:
4391:
4389:
4386:
4384:
4381:
4377:
4374:
4372:
4369:
4368:
4367:
4364:
4360:
4357:
4355:
4352:
4350:
4347:
4345:
4342:
4340:
4337:
4335:
4332:
4330:
4327:
4325:
4322:
4321:
4320:
4317:
4313:
4310:
4308:
4305:
4303:
4300:
4298:
4295:
4293:
4290:
4288:
4285:
4283:
4280:
4278:
4275:
4274:
4273:
4270:
4269:
4267:
4264:
4260:
4257:
4253:
4249:
4245:
4240:
4236:
4232:
4228:
4221:
4216:
4214:
4209:
4207:
4202:
4201:
4198:
4184:
4178:
4173:
4169:
4163:
4158:
4157:
4154:
4145:
4140:
4138:
4133:
4131:
4126:
4125:
4122:
4116:
4113:
4110:
4109:
4098:
4094:
4090:
4086:
4082:
4078:
4073:
4069:
4065:
4061:
4057:
4054:(1–2): 1–24.
4053:
4049:
4044:
4040:
4036:
4032:
4028:
4024:
4020:
4016:
4012:
4011:Intervirology
4007:
4006:
3993:
3989:
3984:
3979:
3975:
3971:
3967:
3963:
3959:
3952:
3944:
3940:
3936:
3932:
3928:
3924:
3917:
3909:
3905:
3901:
3897:
3893:
3889:
3885:
3881:
3874:
3866:
3862:
3858:
3854:
3850:
3846:
3839:
3831:
3827:
3822:
3817:
3813:
3809:
3805:
3798:
3790:
3786:
3781:
3776:
3772:
3768:
3764:
3757:
3749:
3745:
3740:
3735:
3731:
3727:
3723:
3716:
3708:
3704:
3699:
3694:
3690:
3686:
3682:
3675:
3667:
3663:
3658:
3653:
3649:
3645:
3641:
3637:
3633:
3626:
3618:
3614:
3609:
3604:
3600:
3596:
3592:
3585:
3577:
3573:
3568:
3563:
3558:
3553:
3549:
3545:
3541:
3537:
3533:
3526:
3518:
3514:
3509:
3504:
3500:
3496:
3492:
3485:
3483:
3474:
3470:
3465:
3460:
3455:
3450:
3446:
3442:
3439:(6): 3034–9.
3438:
3434:
3430:
3423:
3415:
3411:
3406:
3401:
3397:
3393:
3389:
3385:
3381:
3374:
3366:
3362:
3357:
3352:
3348:
3344:
3340:
3333:
3325:
3321:
3316:
3311:
3307:
3303:
3299:
3295:
3291:
3284:
3276:
3272:
3267:
3262:
3258:
3254:
3250:
3243:
3235:
3231:
3226:
3221:
3217:
3213:
3209:
3205:
3201:
3194:
3186:
3182:
3177:
3172:
3168:
3164:
3160:
3153:
3145:
3141:
3136:
3131:
3127:
3123:
3119:
3112:
3110:
3101:
3097:
3093:
3089:
3084:
3079:
3075:
3071:
3067:
3060:
3052:
3048:
3044:
3040:
3037:(2): 211–21.
3036:
3032:
3024:
3016:
3012:
3007:
3002:
2998:
2994:
2990:
2986:
2982:
2975:
2967:
2963:
2958:
2953:
2949:
2945:
2941:
2934:
2932:
2923:
2919:
2914:
2909:
2905:
2901:
2897:
2890:
2888:
2879:
2875:
2870:
2865:
2861:
2857:
2853:
2849:
2845:
2838:
2830:
2826:
2821:
2816:
2811:
2806:
2802:
2798:
2794:
2790:
2786:
2779:
2771:
2767:
2762:
2757:
2753:
2749:
2745:
2741:
2737:
2730:
2722:
2718:
2713:
2708:
2704:
2700:
2696:
2692:
2688:
2681:
2673:
2669:
2664:
2659:
2654:
2649:
2645:
2641:
2637:
2633:
2629:
2622:
2614:
2610:
2606:
2602:
2598:
2594:
2591:(3): 388–91.
2590:
2586:
2578:
2570:
2566:
2561:
2556:
2552:
2548:
2544:
2540:
2536:
2528:
2519:
2510:
2496:on 2017-08-29
2495:
2491:
2487:
2481:
2473:
2469:
2464:
2459:
2455:
2451:
2447:
2443:
2439:
2432:
2424:
2422:9783662529096
2418:
2414:
2413:
2405:
2397:
2393:
2388:
2383:
2379:
2375:
2371:
2367:
2363:
2356:
2348:
2344:
2340:
2336:
2328:
2320:
2316:
2312:
2308:
2303:
2298:
2295:(9): 675–87.
2294:
2290:
2286:
2279:
2271:
2267:
2262:
2257:
2253:
2249:
2245:
2241:
2237:
2230:
2222:
2218:
2213:
2208:
2204:
2200:
2197:(10): e3077.
2196:
2192:
2188:
2181:
2173:
2169:
2164:
2159:
2155:
2151:
2147:
2140:
2126:
2122:
2116:
2102:
2098:
2092:
2090:
2075:
2071:
2065:
2057:
2053:
2048:
2043:
2038:
2033:
2029:
2025:
2021:
2014:
2006:
2002:
1997:
1992:
1988:
1984:
1980:
1976:
1972:
1965:
1963:
1954:
1950:
1945:
1940:
1935:
1930:
1926:
1922:
1918:
1911:
1903:
1899:
1893:
1885:
1881:
1875:
1868:
1864:
1859:
1857:
1855:
1847:
1843:
1838:
1836:
1834:
1829:
1818:
1815:
1812:
1809:
1806:
1803:
1800:
1797:
1794:
1791:
1788:
1785:
1782:
1779:
1776:
1773:
1770:
1767:
1764:
1761:
1758:
1755:
1753:
1750:
1747:
1744:
1741:
1738:
1735:
1732:
1729:
1726:
1723:
1720:
1717:
1714:
1711:
1708:
1705:
1702:
1699:
1696:
1693:
1690:
1689:
1687:
1685:
1675:
1673:
1669:
1665:
1661:
1656:
1652:
1650:
1646:
1642:
1638:
1634:
1633:
1628:
1627:Herpesviridae
1624:
1623:
1618:
1617:
1612:
1601:
1598:
1594:
1589:
1585:
1581:
1572:
1563:
1561:
1556:
1554:
1550:
1546:
1542:
1538:
1534:
1530:
1526:
1522:
1518:
1514:
1510:
1506:
1502:
1498:
1494:
1490:
1486:
1483:
1479:
1475:
1470:
1468:
1464:
1455:
1453:
1449:
1446:
1442:
1438:
1434:
1422:
1417:
1413:
1409:
1406:
1402:
1395:
1393:
1390:
1386:
1382:
1378:
1375:
1371:
1367:
1360:
1354:
1350:
1347:
1341:
1339:
1335:
1329:
1325:
1322:
1318:
1311:
1309:
1305:
1301:
1297:
1291:
1287:
1284:
1278:
1276:
1272:
1266:
1262:
1259:
1257:RefSeq (mRNA)
1255:
1248:
1247:
1242:
1238:
1235:
1229:
1228:
1223:
1219:
1216:
1214:
1210:
1203:
1202:
1197:
1193:
1190:
1184:
1183:
1178:
1174:
1171:
1169:
1165:
1158:
1157:
1152:
1148:
1145:
1139:
1138:
1133:
1129:
1126:
1124:
1120:
1117:
1114:
1112:
1109:
1105:
1102:
1098:
1094:
1087:
1083:
1078:
1072:
1069:
1067:
1064:
1062:
1059:
1057:
1054:
1052:
1049:
1047:
1044:
1042:
1039:
1037:
1034:
1032:
1029:
1027:
1024:
1022:
1019:
1017:
1014:
1012:
1009:
1007:
1004:
1002:
999:
997:
994:
992:
989:
987:
984:
982:
979:
977:
974:
972:
969:
967:
964:
962:
959:
957:
954:
952:
949:
947:
944:
942:
939:
937:
934:
932:
929:
927:
924:
922:
919:
917:
914:
912:
909:
907:
904:
902:
899:
897:
894:
892:
891:viral process
889:
887:
884:
882:
879:
877:
874:
872:
869:
867:
864:
862:
859:
857:
854:
852:
849:
847:
844:
842:
839:
837:
834:
832:
829:
827:
824:
822:
819:
817:
814:
812:
809:
807:
804:
802:
799:
797:
794:
792:
789:
788:
786:
783:
782:
776:
773:
771:
768:
766:
763:
761:
758:
756:
753:
751:
748:
746:
743:
741:
738:
736:
733:
732:
730:
727:
726:
720:
717:
715:
712:
710:
707:
705:
702:
700:
697:
695:
692:
690:
687:
685:
682:
680:
677:
675:
672:
670:
667:
665:
662:
660:
657:
655:
652:
650:
647:
645:
642:
640:
637:
635:
632:
630:
627:
625:
622:
620:
617:
615:
612:
610:
607:
606:
604:
601:
600:
597:
596:Gene ontology
593:
589:
577:
572:
568:
563:
560:
558:
554:
546:
541:
530:
526:
522:
518:
514:
510:
506:
502:
498:
494:
493:
490:
486:
481:
478:
468:
464:
460:
456:
452:
448:
444:
440:
436:
432:
431:
428:
424:
419:
416:
415:
412:
410:
406:
404:
403:
399:
398:
395:
393:
389:
385:
381:
377:
369:
364:
360:
356:
351:
341:
337:
330:
323:
317:
310:
302:
298:
294:
289:
285:
280:
276:
268:
263:
259:
255:
250:
240:
236:
229:
222:
216:
209:
205:
199:
195:
191:
186:
182:
177:
173:
169:
165:
161:
157:
153:
149:
145:
141:
137:
133:
125:
120:
113:
108:
103:
92:
90:
86:
82:
78:
72:
67:
64:
63:
59:
56:
49:
45:
40:
36:
32:
27:
22:
19:
10995:Lestaurtinib
10986:
10956:
10894:Ritlecitinib
10826:Lestaurtinib
10773:Upadacitinib
10602:Fontolizumab
10593:
10578:
10557:
10546:Rontalizumab
10527:
10385:
10340:Pegacaristim
10331:
10290:
10260:
10253:M-CSF (CSF1)
10233:Mavrilimumab
10229:
10223:Sargramostim
10213:Molgramostim
10198:Ecogramostim
10194:
10167:Nartograstim
10138:
10131:G-CSF (CSF3)
10116:Peginesatide
10096:Epoetin zeta
10061:Epoetin beta
10056:Epoetin alfa
10027:
9769:
9720:Janus kinase
9627:
9582:
9538:
9496:
9488:
9460:
9454:
9448:
9417:
9382:
9370:
9307:
9284:
9266:
9234:
9205:
9086:
9016:
8990:
8942:
8845:
8808:
8792:
8712:
8700:
8654:
8646:
8552:
8498:
8471:
8463:
8434:
8423:
8167:FOX proteins
8127:winged helix
8119:
8090:
8073:
8016:
7936:
7910:
7788:
7754:
7737:
7715:
7698:
7631:
7599:
7453:
7416:
7397:
7343:
7309:
7303:
6997:
6991:
6980:
6974:Antennapedia
6972:
6959:
6947:
6941:
6910:
6868:
6846:
6823:
6802:
6560:
6513:
6459:
6405:
6318:
6296:
6274:
6252:
6235:
6193:
6122:
6004:
5972:
5924:
5896:
5876:
5851:
5814:
5780:Progesterone
5733:
5629:
5477:
5463:
5457:
5441:
5383:
5336:
5328:
5226:
5136:
5085:
5043:
5003:
4976:
4946:
4919:
4753:
4743:
4726:
4709:
4621:
4577:
4545:
4508:
4365:
4255:
4243:
4182:
4167:
4083:(1): 87–94.
4080:
4076:
4051:
4047:
4014:
4010:
3965:
3961:
3951:
3929:(2): 493–7.
3926:
3922:
3916:
3886:(2): 63–71.
3883:
3879:
3873:
3851:(1): 252–7.
3848:
3844:
3838:
3811:
3807:
3797:
3770:
3766:
3756:
3729:
3725:
3715:
3688:
3684:
3674:
3639:
3635:
3625:
3598:
3594:
3584:
3539:
3535:
3525:
3498:
3494:
3436:
3432:
3422:
3387:
3383:
3373:
3346:
3342:
3332:
3297:
3293:
3283:
3256:
3252:
3242:
3207:
3203:
3193:
3166:
3162:
3152:
3125:
3121:
3073:
3069:
3059:
3034:
3030:
3023:
2988:
2984:
2974:
2947:
2943:
2903:
2899:
2851:
2847:
2837:
2792:
2788:
2778:
2746:(1): 73–80.
2743:
2739:
2729:
2694:
2690:
2680:
2635:
2631:
2621:
2588:
2584:
2577:
2542:
2538:
2527:
2518:
2509:
2498:. Retrieved
2494:the original
2489:
2480:
2445:
2441:
2431:
2415:. Springer.
2411:
2404:
2369:
2365:
2355:
2338:
2334:
2327:
2292:
2288:
2278:
2243:
2239:
2229:
2194:
2190:
2180:
2153:
2149:
2139:
2128:. Retrieved
2124:
2115:
2104:. Retrieved
2100:
2077:. Retrieved
2073:
2064:
2027:
2023:
2013:
1981:(7): 641–8.
1978:
1974:
1924:
1920:
1910:
1901:
1892:
1883:
1874:
1681:
1678:Interactions
1668:Posaconazole
1664:Itraconazole
1657:
1653:
1630:
1620:
1614:
1610:
1607:
1586:
1582:
1578:
1569:
1557:
1552:
1548:
1544:
1540:
1536:
1532:
1528:
1524:
1520:
1508:
1504:
1500:
1499:(Interferon-
1496:
1471:
1465:
1461:
1452:STAT protein
1444:
1436:
1432:
1431:
1356:
1331:
1308:NM_001357627
1300:NM_001205314
1296:NM_001205313
1293:
1268:
1244:
1225:
1199:
1180:
1154:
1135:
1115:
1110:
407:
400:
265:191,020,960
252:190,908,460
127:External IDs
74:
18:
11005:Quizartinib
11000:Midostaurin
10889:Peficitinib
10851:Ruxolitinib
10846:Peficitinib
10801:Baricitinib
10763:Ruxolitinib
10758:Peficitinib
10753:Oclacitinib
10748:Momelotinib
10733:Baricitinib
10728:Abrocitinib
10636:Interleukin
10594:Antibodies:
10551:Sifalimumab
10536:Faralimomab
10531:Anifrolumab
10528:Antibodies:
10350:Romiplostim
10335:Eltrombopag
10304:SCF (c-Kit)
10230:Antibodies:
10218:Regramostim
10152:Lenograstim
9308:(4.11) Runt
6963:Homeodomain
6561:zinc finger
5897:subfamily 0
5877:subfamily 6
5852:subfamily 5
5815:subfamily 4
5734:subfamily 3
5630:subfamily 2
5478:subfamily 1
5445:Zinc finger
4688:Neurogenins
4256:(1.1) Basic
4150:PDB gallery
2372:(1): 5–21.
2341:(2): 93–7.
2030:: 1180642.
1927:: 1180642.
1672:Ruxolitinib
1660:Fluconazole
1588:Interferons
1485:interferons
740:nucleoplasm
609:DNA binding
495:granulocyte
465:granulocyte
366:52,201,024
353:52,158,599
105:Identifiers
11034:Categories
10990:Emfilermin
10841:Pacritinib
10743:Filgotinib
10709:inhibitors
10597:Emapalumab
10369:Interferon
10294:Agerafenib
10284:Mirimostim
10274:Lanimostim
10208:Milodistim
10157:Leridistim
10142:Filgrastim
9983:modulators
7841:POU domain
6981:ANTP class
6911:(2.6) WRKY
6194:GLI family
5329:(1.5) RF-X
5227:(1.4) NF-1
4112:FactorBook
2500:2017-06-01
2130:2017-06-01
2106:2017-06-01
2079:2017-06-01
1869:, May 2017
1848:, May 2017
1825:References
1551:timulated
1547:nterferon-
1531:timulated
1527:nterferon-
461:glomerulus
457:lymph node
411:(ortholog)
148:HomoloGene
11015:Sunitinib
11010:Sorafenib
10919:ZM-449829
10909:WHI-P 154
10899:TCS-21311
10836:NSC-33994
10791:Atiprimod
10579:Agonists:
10561:Bifarcept
10386:Agonists:
10332:Agonists:
10264:Cilmostim
10261:Agonists:
10238:Namilumab
10195:Agonists:
10139:Agonists:
10028:Agonists:
9991:Chemokine
9628:see also
9469:Apetala 2
8123:Fork head
6803:(2.4) Cys
6005:(2.3) Cys
4737:Scleraxis
1613:, mostly
1597:phenotype
1507:ctivated
1338:NP_644671
1334:NP_009330
1304:NM_009283
1275:NM_139266
1271:NM_007315
1101:Orthologs
745:nucleolus
735:cytoplasm
156:GeneCards
11055:Proteins
10914:ZM-39923
10831:NSC-7908
10796:AZD-1480
10687:instead.
10667:instead.
10647:instead.
10623:instead.
10541:MEDI-545
10315:instead.
10243:Otilimab
10046:CNTO-530
10002:instead.
9687:Cytokine
8946:MADS box
7086:Homeobox
6998:Hox-like
6992:protoHOX
5753:Estrogen
5748:Androgen
5602:Rev-ErbA
5140:bHLH-ZIP
5115:bHLH-COE
4654:Myogenin
4097:15638726
4068:12039028
4039:22135982
4031:10702714
3992:10848577
3908:38074766
3900:11722592
3865:11594781
3830:12048190
3789:10446176
3707:11278865
3617:11278462
3576:10805787
3517:12807916
3473:11248027
3365:12734330
3275:10764778
3185:12960323
3144:11301323
3100:12153966
3092:11520787
3051:14499622
3015:10848598
2966:12070153
2922:10358079
2878:11909970
2721:10490649
2672:10792030
2613:15983552
2605:12590259
2569:27114460
2472:19436109
2396:26748513
2347:17804871
2319:32798777
2311:12209136
2270:24710278
2221:28981100
2172:15217838
2056:37384298
2047:10298177
2005:27379765
1953:37384298
1944:10298177
1865:–
1844:–
1684:interact
1637:diabetes
1593:mutation
1535:esponse
1482:type III
1458:Function
1454:family.
1405:Wikidata
1080:Sources:
770:dendrite
511:gastrula
445:monocyte
437:appendix
10856:SD-1008
10031:ARA-290
9346:RUNX1T1
9326:CBFA2T3
9321:CBFA2T2
9201:TCF/LEF
7310:NK-like
7304:metaHOX
7007:ParaHox
6948:domains
5639:COUP-TF
5113:Group F
5036:Group E
4969:Group D
4833:Group C
4783:Group B
4727:Paraxis
4592:Group A
3943:9344858
3748:8621447
3666:9135145
3657:1169727
3544:Bibcode
3441:Bibcode
3414:9843502
3405:1171044
3324:8943351
3234:9121453
2829:8986769
2797:Bibcode
2770:9355737
2761:1218765
2640:Bibcode
2560:4920021
2463:2689115
2387:4716683
2261:4054301
2212:5682650
1996:5556363
1867:Ensembl
1846:Ensembl
1611:Candida
1555:enes).
1478:type II
1439:) is a
1213:UniProt
1168:Ensembl
1107:Species
1086:QuickGO
760:cytosol
755:nucleus
449:decidua
386:pattern
112:Aliases
10950:Others
10816:CYT387
10806:CHZ868
10695:Others
10451:IFNA21
10447:IFNA17
10443:IFNA16
10439:IFNA14
10435:IFNA13
10431:IFNA10
9679:Ligand
8059:Bicoid
7324:BARHL2
7319:BARHL1
6901:JMJD1B
6814:HIVEP1
5299:I-SMAD
5267:R-SMAD
5185:MLXIPL
4940:Period
4866:ARNTL2
4671:NeuroD
4095:
4066:
4037:
4029:
3990:
3980:
3941:
3906:
3898:
3863:
3828:
3787:
3746:
3705:
3664:
3654:
3615:
3574:
3564:
3515:
3471:
3461:
3412:
3402:
3363:
3322:
3315:231699
3312:
3273:
3232:
3225:232052
3222:
3183:
3142:
3098:
3090:
3049:
3013:
3003:
2964:
2920:
2876:
2869:133712
2866:
2827:
2817:
2768:
2758:
2719:
2709:
2670:
2660:
2611:
2603:
2567:
2557:
2470:
2460:
2419:
2394:
2384:
2345:
2317:
2309:
2268:
2258:
2219:
2209:
2170:
2054:
2044:
2003:
1993:
1951:
1941:
1813:, and
1752:ISGF3G
1740:IFNAR2
1734:GNB2L1
1686:with:
1641:thymus
1474:type I
1391:search
1389:PubMed
1246:P42225
1227:P42224
1123:Entrez
557:BioGPS
503:spleen
499:thymus
244:2q32.2
144:103063
136:600555
10490:IFNB3
10486:IFNB1
10427:IFNA8
10423:IFNA7
10419:IFNA6
10415:IFNA5
10411:IFNA4
10407:IFNA2
10403:IFNA1
9828:PIAS4
9823:PIAS3
9818:PIAS2
9813:PIAS1
9795:STAT6
9790:STAT5
9785:STAT4
9780:STAT3
9775:STAT2
9770:STAT1
9609:Sigma
9474:EREBP
9458:EREBP
9449:(0.5)
9418:(0.3)
9341:RUNX3
9336:RUNX2
9331:RUNX1
9275:TFCP2
9196:SSRP1
9017:(4.7)
9007:TBPL1
8991:(4.6)
8943:(4.4)
8793:(4.2)
8734:NFKB2
8729:NFKB1
8724:NF-κB
8713:(4.1)
8637:MYBL2
8424:(3.4)
8120:(3.3)
8069:BICD2
8044:SHOX2
8012:PROP1
7996:PRRX
7906:SATB2
7851:BRN-3
7846:PIT-1
7738:PKNOX
7653:TALE
7649:NOBOX
7622:HESX1
7595:CUTL1
7577:other
7471:NANOG
7334:BARX2
7329:BARX1
7081:MEOX2
7076:MEOX1
6960:(3.1)
6869:JARID
6842:GRLF1
6837:DIDO1
6497:Zbtb7
6487:TSHZ3
6455:PRDM9
6253:HIVEP
6118:ATBF1
6072:TFIIH
6057:TFIIF
6040:TFIIE
6035:TFIID
6030:TFIIB
6025:TFIIA
5995:TRPS1
5861:LRH-1
5839:NURR1
5829:NGFIB
5657:Ear-2
5458:(2.1)
5200:SREBP
5137:(1.3)
4899:NPAS
4888:EPAS1
4873:CLOCK
4861:ARNTL
4835:bHLH-
4811:n-Myc
4806:l-Myc
4801:c-Myc
4791:FIGLA
4773:Twist
4732:TCF15
4639:MESP2
4617:ATOH1
4610:ASCL2
4605:ASCL1
4536:NFIL3
4467:GABPA
4462:DDIT3
4393:C/EBP
4388:BLZF1
4349:c-Jun
4339:FOSL2
4334:FOSL1
4324:c-Fos
4115:STAT1
4035:S2CID
3983:85828
3904:S2CID
3567:25817
3464:30602
3096:S2CID
3070:Blood
3006:85895
2820:26361
2712:84707
2663:25807
2609:S2CID
2539:Blood
2315:S2CID
2150:Blood
1817:TRADD
1805:STAT3
1799:STAT2
1781:PRKCD
1775:PIAS1
1704:CD117
1698:C-jun
1692:BRCA1
1517:STAT2
1503:amma-
1493:STAT3
1489:IFN-γ
1480:, or
1445:STAT1
1437:STAT1
1156:20846
1116:Mouse
1111:Human
1082:Amigo
519:blood
409:Mouse
402:Human
349:Start
284:Mouse
248:Start
181:Human
160:STAT1
152:21428
119:STAT1
24:STAT1
10929:TYK2
10871:JAK3
10783:JAK2
10720:JAK1
10685:here
10683:See
10665:here
10663:See
10656:TGFβ
10645:here
10643:See
10621:here
10313:here
10311:See
10000:here
9998:See
9934:IRF8
9929:IRF7
9924:IRF6
9919:IRF5
9914:IRF4
9909:IRF3
9904:IRF2
9899:IRF1
9881:CISH
9838:SOCS
9805:PIAS
9762:STAT
9743:TYK2
9738:JAK3
9733:JAK2
9728:JAK1
9578:MNDA
9497:ARID
9452:AP-2
9439:RBL2
9434:RBL1
9408:HBP1
9391:HMGA
9298:YBX1
9293:CSDA
9228:LEF1
9060:HMGN
9033:HMGB
8954:Mef2
8933:MYRF
8921:TBR2
8916:TBR1
8864:TP63
8804:STAT
8796:STAT
8756:NFAT
8749:RELB
8744:RELA
8699:(4)
8580:FLI1
8546:SPIB
8247:D4L6
8242:D4L5
8237:D4L4
8232:D4L3
8227:D4L1
8091:PITX
8054:VSX2
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7034:PDX1
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6919:WRKY
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6514:ZBTB
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6275:IKZF
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5531:PPAR
5464:(Cys
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5262:SMAD
5217:USF1
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4568:XBP1
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4319:AP-1
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3744:PMID
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340:Band
301:Chr.
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