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Secobarbital

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824:, obtained the rights to market and to use the trade name Seconal from Eli Lilly in 1998 and did so until September 2008. The actual manufacturer of Seconal subsequent to the time Eli Lilly manufactured the drug was Ohm Pharmaceuticals, a wholly owned subsidiary of Ranbaxy. The rights to market Seconal were then sold to Marathon Pharmaceuticals, which became the marketer and trade-name holder. At the time Marathon Pharmaceuticals obtained ownership of the brand name, the retail price for one 100 mg capsule (depending upon prescription size and pharmacy) averaged about one U.S. dollar. During the time Marathon owned the brand name, the company greatly increased the price of the drug. By February 2015, when Marathon sold the rights to 582: 559: 49: 810: 40: 828:, the average retail price per 100 mg capsule had risen to over thirty dollars. Since its acquisition of the trade name, Valeant Pharmaceuticals made little, if any, change to the pricing of Seconal. Despite the price increases implemented by Marathon Pharmaceuticals, Seconal was still manufactured by Ohm. In the United States, Seconal is available only in 100 mg capsules, as a 843:
were in existence after Eli Lilly's patent on Seconal expired, currently there are no companies that manufacture the drug generically in the United States. Until 2020, Valeant was the sole marketer of Seconal in the United States. As of 2021, Valeant discontinued the product, and Bausch Health became
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Secobarbital was widely abused for recreational purposes in the 1960s, 1970s, and 1980s, and accidental overdose was associated with the drug. Lilly's Seconal came in a bright orange/red bullet shaped capsule known as a Pulvule. Prescription use of secobarbital decreased beginning in the early 1980s
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had become increasingly common. Secobarbital has acquired many nicknames, the most common being "reds," "red devils," or "red dillies" (because of the color of the capsules). Other common nicknames are "seccies," "Cardinals," "ruby slippers," and, according to the Wegman's School of Pharmacy
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administered intravenously by a doctor, followed by a muscle relaxant. As of 2010, only 15% of those who died by euthanasia opted for orally consuming the lethal drug(s), the rest choosing to have the drugs administered intravenously by a doctor instead.
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family. Seconal was widely abused, known on the street as "red devils" or "reds". Among the barbiturates, secobarbital carries a particularly high risk of abuse and addiction, largely responsible for its falling out of use.
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Fraser HF, Wikler A, Essig CF, Isbell H (January 1958). "Degree of physical dependence induced by secobarbital or pentobarbital".
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Secobarbital may produce psychological addiction and produces physical dependence if used for an extended period of time.
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of secobarbital has been reported to be between 125 mg/kg (rat, oral) and 267 mg/kg (mouse, oral).
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for the treatment of insomnia, and subsequently by other companies as described below, under the brand name
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allegedly either died by suicide or of accidentally overdosing on secobarbital. Seconal was used to induce
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InChI=1S/C12H18N2O3/c1-4-6-8(3)12(7-5-2)9(15)13-11(17)14-10(12)16/h5,8H,2,4,6-7H2,1,3H3,(H2,13,14,15,16,17)
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curriculum, "red hearts". A less common nickname is "dolls"; this was partly responsible for the title of
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previously experienced various issues in their attempts to produce 100 mg secobarbital capsules.
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Essig CF (March 1967). "Clinical and experimental aspects of barbiturate withdrawal convulsions".
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In the United States, secobarbital and pentobarbital are the most common drugs prescribed under
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the sole supplier of Seconal. Bausch Health stopped manufacturing the product in January 2022.
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into docility before he was then killed in his bed in the early hours of December 4, 1969.
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The sodium salt of secobarbital is classified separately from the free acid, as follows:
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Loggers ET, Starks H, Shannon-Dudley M, Back AL, Appelbaum FR, Stewart FM (April 2013).
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in short surgical, diagnostic, or therapeutic procedures which are minimally painful.
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In 2017, secobarbital was made available for physician-assisted suicide in Canada.
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Black against empire : the history and politics of the Black Panther Party
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10.1002/1097-0142(19860815)58:4<959::AID-CNCR2820580426>3.0.CO;2-Z
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derivative drug that was patented in 1934 in the United States. It possesses
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laws in Oregon since 1998, Washington since 2008, and Vermont since 2013.
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symptoms may occur if long-term use is abruptly ended and can include:
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from the original on 24 April 2018 – via www.theguardian.com.
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or 15 grams of secobarbital, or they can choose to have 2 grams of
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Richards PD, Flaum MA, Bateman M, Kardinal CG (August 1986).
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King P (December 28, 1978). "How Jones Used Drugs".
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Full prescribing information for the United States.
1623:. Waldo E. Martin. Oakland. pp. 245, 237–246. 1377: 759:properties. In the United Kingdom, it was known as 406: 1795: 1061:, and other sedatives, hypnotics, and analgesics. 6097:Unsorted benzodiazepine site positive modulators: 1041:In 1978, 1000 pills of Seconal were recovered in 6149: 386: 886:Possible side effects of secobarbital include: 361: 1927: 1378:le Riche WH, Csima A, Dobson M (August 1966). 997: 3530: 2942:Serotonin antagonists and reuptake inhibitors 1913: 1778:. Oregon Health Authority. January 28, 2014. 1773:"Oregon's Death with Dignity Act 2013 Report" 1468:Miller RR, DeYoung DV, Paxinos J (May 1970). 1360:"Drug Shortage Detail: Secobarbital Capsules" 836:powder that is soluble in water and ethanol. 792:Use as a preoperative medication to produce 3546: 3331: 1796:Hedberg K, Hopkins D, Kohn M (March 2003). 1519:Journal of the American Medical Association 155: 3537: 3523: 1920: 1906: 1651:: CS1 maint: location missing publisher ( 580: 557: 446: 1813: 1740: 1706:"Euthanasiedrank verliest terrein(Dutch)" 1493: 1436: 1395: 1380:"A clinical trial of four hypnotic drugs" 1220: 466: 6168:Drugs developed by Eli Lilly and Company 1242: 993:Possible death as a result of withdrawal 919:Agitation, irritability, or excitability 808: 1785:from the original on November 18, 2014. 1703: 1680: 1197: 1195: 1045:, along with substantial quantities of 553: 426: 94: 14: 6150: 1836: 1681:unknown; et al. (July 29, 2010). 1165: 847: 571: 243: 218: 3518: 1901: 1858:"Secobarbital - Human Health Effects" 1616: 1551: 1201: 526: 506: 230: 80: 6138:GABA metabolism/transport modulators 1665: 1384:Canadian Medical Association Journal 1373: 1371: 1369: 1325: 1323: 1238: 1236: 1192: 214:(Special prescription form required) 145: 5755:Trichloroethane (methyl chloroform) 1849: 1802:The New England Journal of Medicine 1729:The New England Journal of Medicine 1693:from the original on June 29, 2016. 1073:, individuals have two options for 486: 377: 24: 4818:11-Methoxy-12-hydroxydehydrokavain 1879:Marathon Pharmaceuticals - Seconal 1566:10.1111/j.1528-1157.1967.tb03816.x 1276:. Marathonpharma.com. 2013-07-31. 1065:Use in animal and human euthanasia 25: 6184: 5565:Acetylglycinamide chloral hydrate 2647:Acetylglycinamide chloral hydrate 1872: 1366: 1320: 1233: 1864:from the original on 2018-02-22. 1531:10.1001/jama.1958.02990020014002 1210:from the original on 2007-12-02. 611: 605: 47: 38: 5985:Menthyl isovalerate (validolum) 1855: 1830: 1789: 1765: 1716: 1697: 1674: 1659: 1610: 1588: 1545: 1510: 1461: 1412: 1341:from the original on 2016-04-07 1309:from the original on 2016-03-29 1280:from the original on 2012-06-28 1255:from the original on 2016-03-23 1181:from the original on 2023-08-03 881: 804: 776:Secobarbital is indicated for: 698:Key:KQPKPCNLIDLUMF-UHFFFAOYSA-N 673:O=C1NC(NC(C1(CC=C)C(CCC)C)=O)=O 206: 4934:Allopregnanolone (brexanolone) 1837:Bryden J (November 17, 2017). 1352: 1291: 1266: 1214: 1159: 771: 617: 599: 195: 182: 13: 1: 6130:Receptor/signaling modulators 4686:Ampelopsin (dihydromyricetin) 1303:Marathon Pharmaceuticals, LLC 1152: 965: 941:Increased sensitivity to pain 250:Psychotropic Schedule II 5880:ergoloid (dihydroergotoxine) 4965:anabolic-androgenic steroids 3747:Butabarbital/Secbutabarbital 3552:receptor positive modulators 1683:"Hulp bij zelfdoding(Dutch)" 1474:Postgraduate Medical Journal 1243:Dembosky A (23 March 2016). 1099:Ranbaxy Laboratories Limited 841:generic versions of the drug 7: 4520:Triflunordazepam (Ro5-2904) 3173:Tetracyclic antidepressants 2987:Tetracyclic antidepressants 1815:10.1056/NEJM200303063481022 1704:Croonen H (April 1, 2010). 1140: 998:Recreational and lethal use 10: 6189: 4848:5,6,7,8-Tetrahydroyangonin 813:Secobarbital sodium, 100mg 589:Chemical and physical data 27:Obsolete sedative-hypnotic 6123: 5773: 5541: 5478: 5445: 5412: 5384: 5098: 5040:Pregnanolone (eltanolone) 4919: 4876: 4787: 4759: 4671: 4553: 3995: 3682: 3583:Chlorobutanol (cloretone) 3558: 3376: 3329: 3301: 3268: 3248: 3194: 3150:Tricyclic antidepressants 3135: 3123: 3066: 3008: 2964:Tricyclic antidepressants 2932: 2869: 2857: 2786: 2634: 2571: 2538: 2520: 2452: 2399: 2356: 2328: 2270: 2147: 2004: 1956: 1944: 1892:RxList.com - Secobarbital 1107:It is a component in the 901:Impaired balance (Ataxia) 895:Impaired motor functions 877:Molecular weight: 260.265 727:, originally marketed by 706: 681: 661: 639: 626: 593: 588: 569: 537: 517: 497: 477: 457: 437: 417: 397: 372: 352: 328: 323: 311: 298: 286: 276: 266: 258: 172: 167: 132: 120: 102: 88: 82:Consumer Drug Information 70: 60: 55: 46: 37: 6134:GABA receptor modulators 6044:sulfonmethane (sulfonal) 2735:Sulfonmethane (sulfonal) 1177:(published 2023-04-04). 3222:Atypical antipsychotics 3036:Atypical antipsychotics 1486:10.1136/pgmj.46.535.314 1175:Diário Oficial da União 826:Valeant Pharmaceuticals 818:Ranbaxy Pharmaceuticals 786:Temporary treatment of 6020:Retigabine (ezogabine) 5296:Lirequinil (Ro41-3696) 4863:7,8-Dihydromethysticin 4853:5,6-Dehydromethysticin 3732:Benzylbutylbarbiturate 3396:Chlorophenylalkyldiols 3204:Typical antipsychotics 3018:Typical antipsychotics 1668:San Francisco Examiner 1095:physician aid-in-dying 832:. The salt is a white 814: 1894:Consumer information. 1742:10.1056/NEJMsa1213398 1222:US patent 1954429 898:Impaired coordination 812: 729:Eli Lilly and Company 6075:constituents (e.g., 5859:Deuterated etifoxine 4921:Neuroactive steroids 4891:Apronal (apronalide) 4743:constituents (e.g., 4360:N-Desalkylflurazepam 3353:Gabapentin enacarbil 2401:Neuroactive steroids 2371:Apronal (apronalide) 1602:. 21 February 2018. 949:Difficulty breathing 856:CAS number: 309-43-3 735:) is a short-acting 191:(Psychoactive drugs) 6158:General anesthetics 5868:dihydroergocryptine 5180:Pyrazolopyrimidines 4838:5,6-Dihydroyangonin 4823:7,8-Dihydroyangonin 4010:3-Hydroxyphenazepam 3852:Methylphenobarbital 1274:"» Seconal Sodium®" 1015:Valley of the Dolls 859:Chemical formula: C 848:Secobarbital sodium 34: 5962:4-O-methylhonokiol 5625:Dichloralphenazone 5523:Methylmethaqualone 5100:Nonbenzodiazepines 4813:Desmethoxyyangonin 4808:11-Hydroxyyangonin 4803:11-Methoxyyangonin 4798:10-Methoxyyangonin 4185:Ethyl carfluzepate 3787:Cyclopentobarbital 3418:Diethylpropanediol 2700:Dichloralphenazone 2616:Methylmethaqualone 2454:Nonbenzodiazepines 1981:Diethylpropanediol 1884:2009-05-08 at the 1028:Tennessee Williams 945:Allergic reactions 815: 30: 6145: 6144: 6105:MRK-409 (MK-0343) 5876:dihydroergotamine 5819:potassium bromide 5813:compounds (e.g., 5760:Trichloroethylene 5528:Nitromethaqualone 5447:Pyrazolopyridines 4949:3α-Androstanediol 4843:7,8-Dihydrokavain 4195:Ethyl loflazepate 3972:Thiotetrabarbital 3588:Ethanol (alcohol) 3512: 3511: 3264: 3263: 3062: 3061: 2782: 2781: 2663:Potassium bromide 2621:Nitromethaqualone 2129:Thiotetrabarbital 1976:Ethanol (alcohol) 1735:(15): 1417–1424. 1630:978-0-520-96645-1 1032:Dorothy Kilgallen 1030:, and journalist 1010:Jacqueline Susann 718: 717: 652:Interactive image 539:CompTox Dashboard 247: 234: 222: 209: 198: 186: 113:D (United States) 16:(Redirected from 6180: 5864:Dihydroergolines 5781:3-Hydroxybutanal 5414:Piperidinediones 5147:Imidazopyridines 4681:6-Methylapigenin 4613:Hydroxyphenamate 4485:SH-053-R-CH3-2′F 4190:Ethyl dirazepate 4070:Chlordiazepoxide 3962:Thiobutabarbital 3674:Trifluoroethanol 3664:Trichloroethanol 3654:-Pentanol (2M2B) 3548: 3539: 3532: 3525: 3516: 3515: 3437:muscle relaxants 3340: 3337: 3133: 3132: 2867: 2866: 2804:4-Fluorophenibut 2540:Piperidinediones 2414:Allopregnanolone 1996:Trichloroethanol 1954: 1953: 1922: 1915: 1908: 1899: 1898: 1866: 1865: 1853: 1847: 1846: 1834: 1828: 1827: 1817: 1793: 1787: 1786: 1784: 1777: 1769: 1763: 1762: 1744: 1720: 1714: 1713: 1701: 1695: 1694: 1678: 1672: 1671: 1663: 1657: 1656: 1650: 1642: 1617:Bloom J (2016). 1614: 1608: 1607: 1592: 1586: 1585: 1549: 1543: 1542: 1514: 1508: 1507: 1497: 1480:(535): 314–317. 1470:"Hypnotic drugs" 1465: 1459: 1458: 1440: 1416: 1410: 1409: 1399: 1375: 1364: 1363: 1356: 1350: 1349: 1347: 1346: 1327: 1318: 1317: 1315: 1314: 1295: 1289: 1288: 1286: 1285: 1270: 1264: 1263: 1261: 1260: 1240: 1231: 1230: 1229: 1225: 1218: 1212: 1211: 1199: 1190: 1189: 1187: 1186: 1163: 984:Lack of appetite 714: 713: 654: 634: 619: 613: 607: 601: 584: 573: 562: 561: 547: 545: 530: 510: 490: 470: 450: 430: 410: 390: 380: 379: 365: 303: 245: 242: 232: 229: 220: 217: 208: 205: 197: 194: 184: 181: 159: 149: 98: 84: 51: 42: 35: 33: 29: 21: 6188: 6187: 6183: 6182: 6181: 6179: 6178: 6177: 6173:Allyl compounds 6148: 6147: 6146: 6141: 6119: 6077:isovaleric acid 6040:Sulfonylalkanes 5938:Hopantenic acid 5922:tolfenamic acid 5910:flufenamic acid 5872:dihydroergosine 5815:lithium bromide 5774:Others/unsorted 5769: 5630:Dichloromethane 5605:Chloral hydrate 5600:Chloral betaine 5537: 5474: 5441: 5408: 5380: 5109:Cyclopyrrolones 5094: 5000:Etiocholanolone 4915: 4872: 4833:5-Hydroxykavain 4783: 4755: 4667: 4549: 3997:Benzodiazepines 3991: 3802:Ethallobarbital 3797:Enallylpropymal 3678: 3659:Tribromoethanol 3646:-Butanol (2M2P) 3592:alcoholic drink 3554: 3551: 3543: 3513: 3508: 3372: 3335: 3325: 3297: 3260: 3244: 3190: 3137:Antidepressants 3128: 3119: 3090:Dexmedetomidine 3071: 3058: 3004: 2934:Antidepressants 2928: 2889:Diphenhydramine 2862: 2853: 2791: 2778: 2767:Isovaleric acid 2730:Sulfonylalkanes 2685:Chloral hydrate 2680:Chloral betaine 2658:Lithium bromide 2630: 2567: 2534: 2516: 2448: 2395: 2352: 2324: 2266: 2149:Benzodiazepines 2143: 2049:Ethallobarbital 2000: 1949: 1940: 1926: 1886:Wayback Machine 1875: 1870: 1869: 1854: 1850: 1835: 1831: 1808:(10): 961–964. 1794: 1790: 1782: 1775: 1771: 1770: 1766: 1721: 1717: 1710:Medisch contact 1702: 1698: 1679: 1675: 1664: 1660: 1644: 1643: 1631: 1615: 1611: 1594: 1593: 1589: 1550: 1546: 1515: 1511: 1466: 1462: 1417: 1413: 1376: 1367: 1358: 1357: 1353: 1344: 1342: 1329: 1328: 1321: 1312: 1310: 1297: 1296: 1292: 1283: 1281: 1272: 1271: 1267: 1258: 1256: 1241: 1234: 1227: 1219: 1215: 1200: 1193: 1184: 1182: 1164: 1160: 1155: 1143: 1135: 1067: 1005:benzodiazepines 1000: 968: 884: 874: 870: 866: 862: 850: 807: 774: 761:quinalbarbitone 709: 707: 702: 699: 694: 689: 688: 677: 674: 669: 668: 657: 632: 622: 616: 610: 604: 565: 541: 533: 513: 493: 473: 453: 433: 413: 393: 376: 368: 348: 345: 336: 335: 301: 278:Protein binding 268:Bioavailability 260:Pharmacokinetic 254: 163: 123: 116: 105: 28: 23: 22: 15: 12: 11: 5: 6186: 6176: 6175: 6170: 6165: 6160: 6143: 6142: 6124: 6121: 6120: 6118: 6117: 6112: 6107: 6102: 6093: 6092: 6085:valerenic acid 6070: 6065: 6055: 6037: 6032: 6027: 6022: 6017: 6012: 6007: 6002: 5997: 5992: 5987: 5982: 5977: 5955: 5950: 5945: 5940: 5935: 5930: 5925: 5914:mefenamic acid 5903: 5898: 5893: 5888: 5883: 5861: 5856: 5851: 5846: 5841: 5836: 5831: 5826: 5823:sodium bromide 5808: 5798: 5793: 5788: 5783: 5777: 5775: 5771: 5770: 5768: 5767: 5762: 5757: 5752: 5747: 5742: 5737: 5732: 5727: 5722: 5717: 5712: 5707: 5702: 5697: 5692: 5690:Methoxypropane 5687: 5685:Methoxyflurane 5682: 5677: 5672: 5667: 5662: 5657: 5652: 5647: 5645:Ethyl chloride 5642: 5637: 5632: 5627: 5622: 5617: 5612: 5607: 5602: 5597: 5592: 5587: 5582: 5577: 5572: 5567: 5562: 5557: 5551: 5549: 5539: 5538: 5536: 5535: 5530: 5525: 5520: 5515: 5510: 5505: 5500: 5495: 5490: 5484: 5482: 5480:Quinazolinones 5476: 5475: 5473: 5472: 5467: 5462: 5457: 5451: 5449: 5443: 5442: 5440: 5439: 5434: 5429: 5424: 5418: 5416: 5410: 5409: 5407: 5406: 5401: 5396: 5390: 5388: 5382: 5381: 5379: 5378: 5373: 5368: 5363: 5358: 5353: 5348: 5343: 5338: 5333: 5328: 5323: 5318: 5313: 5308: 5303: 5298: 5293: 5288: 5283: 5278: 5273: 5268: 5263: 5258: 5253: 5248: 5243: 5238: 5233: 5223: 5222: 5217: 5212: 5207: 5202: 5197: 5192: 5187: 5175: 5174: 5169: 5164: 5159: 5154: 5142: 5141: 5136: 5131: 5126: 5121: 5116: 5104: 5102: 5096: 5095: 5093: 5092: 5087: 5082: 5077: 5072: 5067: 5062: 5057: 5052: 5047: 5042: 5037: 5032: 5027: 5022: 5017: 5012: 5007: 5002: 4997: 4992: 4987: 4982: 4977: 4972: 4967: 4961: 4956: 4951: 4946: 4941: 4936: 4931: 4925: 4923: 4917: 4916: 4914: 4913: 4908: 4903: 4898: 4893: 4888: 4882: 4880: 4874: 4873: 4871: 4870: 4865: 4860: 4855: 4850: 4845: 4840: 4835: 4830: 4825: 4820: 4815: 4810: 4805: 4800: 4794: 4792: 4785: 4784: 4782: 4781: 4776: 4771: 4765: 4763: 4757: 4756: 4754: 4753: 4748: 4738: 4733: 4728: 4723: 4718: 4713: 4708: 4703: 4698: 4693: 4688: 4683: 4677: 4675: 4669: 4668: 4666: 4665: 4660: 4655: 4650: 4645: 4640: 4635: 4630: 4625: 4620: 4615: 4610: 4605: 4600: 4595: 4590: 4585: 4580: 4575: 4570: 4565: 4559: 4557: 4551: 4550: 4548: 4547: 4542: 4537: 4532: 4527: 4522: 4517: 4512: 4507: 4502: 4497: 4492: 4487: 4482: 4477: 4472: 4467: 4462: 4457: 4452: 4447: 4442: 4437: 4432: 4427: 4422: 4417: 4412: 4407: 4402: 4397: 4392: 4387: 4382: 4377: 4372: 4367: 4362: 4357: 4352: 4347: 4342: 4337: 4332: 4327: 4322: 4317: 4312: 4307: 4302: 4297: 4292: 4287: 4282: 4277: 4272: 4267: 4262: 4257: 4252: 4247: 4242: 4237: 4232: 4227: 4222: 4217: 4212: 4207: 4202: 4197: 4192: 4187: 4182: 4177: 4172: 4167: 4162: 4157: 4152: 4147: 4142: 4137: 4132: 4127: 4122: 4117: 4112: 4107: 4102: 4097: 4092: 4087: 4082: 4077: 4072: 4067: 4062: 4057: 4052: 4047: 4042: 4037: 4032: 4027: 4022: 4017: 4012: 4007: 4001: 3999: 3993: 3992: 3990: 3989: 3984: 3979: 3974: 3969: 3964: 3959: 3954: 3949: 3944: 3939: 3934: 3929: 3924: 3919: 3914: 3909: 3904: 3902:Propylbarbital 3899: 3894: 3889: 3884: 3879: 3874: 3869: 3864: 3859: 3854: 3849: 3844: 3839: 3834: 3829: 3824: 3819: 3814: 3809: 3804: 3799: 3794: 3789: 3784: 3779: 3777:Crotylbarbital 3774: 3769: 3764: 3759: 3754: 3749: 3744: 3742:Brophebarbital 3739: 3737:Brallobarbital 3734: 3729: 3724: 3719: 3714: 3709: 3704: 3699: 3694: 3688: 3686: 3680: 3679: 3677: 3676: 3671: 3666: 3661: 3656: 3648: 3640: 3635: 3630: 3625: 3623:Methylpentynol 3620: 3615: 3610: 3605: 3600: 3595: 3585: 3580: 3575: 3570: 3564: 3562: 3556: 3555: 3549: 3542: 3541: 3534: 3527: 3519: 3510: 3509: 3507: 3506: 3501: 3496: 3491: 3486: 3484:Passion flower 3481: 3471: 3466: 3465: 3464: 3459: 3454: 3449: 3444: 3430: 3425: 3420: 3415: 3414: 3413: 3408: 3403: 3393: 3392: 3391: 3380: 3378: 3374: 3373: 3371: 3370: 3365: 3360: 3355: 3350: 3344: 3342: 3333: 3327: 3326: 3324: 3323: 3318: 3313: 3307: 3305: 3299: 3298: 3296: 3295: 3290: 3285: 3280: 3274: 3272: 3266: 3265: 3262: 3261: 3259: 3258: 3252: 3250: 3246: 3245: 3243: 3242: 3241: 3240: 3234: 3229: 3219: 3218: 3217: 3211: 3209:Chlorpromazine 3200: 3198: 3196:Antipsychotics 3192: 3191: 3189: 3188: 3187: 3186: 3180: 3170: 3169: 3168: 3162: 3157: 3147: 3141: 3139: 3130: 3126: 3121: 3120: 3118: 3117: 3112: 3107: 3102: 3097: 3092: 3087: 3082: 3076: 3074: 3069: 3064: 3063: 3060: 3059: 3057: 3056: 3055: 3054: 3048: 3043: 3033: 3032: 3031: 3025: 3023:Chlorpromazine 3014: 3012: 3010:Antipsychotics 3006: 3005: 3003: 3002: 3001: 3000: 2994: 2984: 2983: 2982: 2976: 2971: 2961: 2960: 2959: 2954: 2949: 2938: 2936: 2930: 2929: 2927: 2926: 2921: 2916: 2911: 2906: 2901: 2896: 2891: 2886: 2884:Cyproheptadine 2881: 2875: 2873: 2871:Antihistamines 2864: 2860: 2855: 2854: 2852: 2851: 2846: 2841: 2836: 2831: 2828:sodium oxybate 2821: 2816: 2811: 2806: 2801: 2799:1,4-Butanediol 2795: 2793: 2789: 2784: 2783: 2780: 2779: 2777: 2776: 2775: 2774: 2772:Valerenic acid 2769: 2764: 2754: 2749: 2748: 2747: 2742: 2737: 2727: 2722: 2717: 2712: 2707: 2702: 2697: 2692: 2687: 2682: 2677: 2672: 2671: 2670: 2668:Sodium bromide 2665: 2660: 2649: 2644: 2638: 2636: 2632: 2631: 2629: 2628: 2623: 2618: 2613: 2608: 2603: 2598: 2593: 2588: 2583: 2577: 2575: 2573:Quinazolinones 2569: 2568: 2566: 2565: 2560: 2555: 2550: 2544: 2542: 2536: 2535: 2533: 2532: 2526: 2524: 2518: 2517: 2515: 2514: 2509: 2504: 2499: 2494: 2489: 2484: 2479: 2474: 2469: 2464: 2458: 2456: 2450: 2449: 2447: 2446: 2441: 2436: 2431: 2426: 2421: 2416: 2411: 2405: 2403: 2397: 2396: 2394: 2393: 2388: 2383: 2378: 2373: 2368: 2362: 2360: 2354: 2353: 2351: 2350: 2345: 2340: 2334: 2332: 2326: 2325: 2323: 2322: 2317: 2312: 2307: 2302: 2297: 2292: 2287: 2282: 2276: 2274: 2268: 2267: 2265: 2264: 2259: 2254: 2249: 2244: 2239: 2234: 2229: 2224: 2219: 2214: 2209: 2204: 2199: 2194: 2189: 2184: 2179: 2174: 2169: 2164: 2159: 2153: 2151: 2145: 2144: 2142: 2141: 2136: 2131: 2126: 2121: 2116: 2111: 2106: 2101: 2096: 2094:Propylbarbital 2091: 2086: 2081: 2076: 2071: 2066: 2061: 2056: 2051: 2046: 2041: 2036: 2031: 2026: 2021: 2016: 2010: 2008: 2002: 2001: 1999: 1998: 1993: 1991:Methylpentynol 1988: 1983: 1978: 1973: 1968: 1962: 1960: 1951: 1947: 1942: 1941: 1925: 1924: 1917: 1910: 1902: 1896: 1895: 1889: 1874: 1873:External links 1871: 1868: 1867: 1848: 1829: 1788: 1764: 1715: 1696: 1673: 1658: 1629: 1609: 1587: 1544: 1525:(2): 126–129. 1509: 1460: 1431:(4): 959–962. 1411: 1390:(7): 300–302. 1365: 1351: 1319: 1290: 1265: 1232: 1213: 1204:"Secobarbital" 1191: 1169:(2023-03-31). 1157: 1156: 1154: 1151: 1150: 1149: 1142: 1139: 1133: 1066: 1063: 1003:by which time 999: 996: 995: 994: 991: 988: 985: 982: 979: 967: 964: 963: 962: 961: 960: 955: 950: 942: 939: 934: 931: 926: 923: 920: 917: 914: 909: 908: 907: 902: 899: 893: 883: 880: 879: 878: 875: 872: 868: 864: 860: 857: 849: 846: 822:Daiichi Sankyo 806: 803: 802: 801: 790: 784: 773: 770: 765:benzodiazepine 745:anticonvulsant 716: 715: 704: 703: 701: 700: 697: 695: 692: 684: 683: 682: 679: 678: 676: 675: 672: 664: 663: 662: 659: 658: 656: 655: 647: 645: 637: 636: 630: 624: 623: 620: 614: 608: 602: 597: 591: 590: 586: 585: 575: 567: 566: 564: 563: 550: 548: 535: 534: 532: 531: 523: 521: 515: 514: 512: 511: 503: 501: 495: 494: 492: 491: 483: 481: 475: 474: 472: 471: 463: 461: 455: 454: 452: 451: 443: 441: 435: 434: 432: 431: 423: 421: 415: 414: 412: 411: 403: 401: 395: 394: 392: 391: 383: 381: 370: 369: 367: 366: 358: 356: 350: 349: 347: 346: 339: 331: 330: 329: 326: 325: 321: 320: 315: 309: 308: 305: 296: 295: 290: 284: 283: 280: 274: 273: 270: 264: 263: 256: 255: 253: 252: 240: 227: 215: 203: 192: 178: 176: 170: 169: 165: 164: 162: 161: 138: 136: 130: 129: 126: 124:administration 118: 117: 115: 114: 110: 108: 100: 99: 92: 86: 85: 78: 68: 67: 64: 58: 57: 53: 52: 44: 43: 26: 9: 6: 4: 3: 2: 6185: 6174: 6171: 6169: 6166: 6164: 6161: 6159: 6156: 6155: 6153: 6140: 6139: 6135: 6131: 6128: 6122: 6116: 6113: 6111: 6108: 6106: 6103: 6101: 6098: 6095: 6094: 6090: 6086: 6082: 6081:isovaleramide 6078: 6074: 6071: 6069: 6066: 6063: 6059: 6056: 6053: 6049: 6045: 6041: 6038: 6036: 6033: 6031: 6028: 6026: 6023: 6021: 6018: 6016: 6013: 6011: 6008: 6006: 6003: 6001: 5998: 5996: 5993: 5991: 5988: 5986: 5983: 5981: 5978: 5975: 5971: 5967: 5963: 5959: 5956: 5954: 5951: 5949: 5946: 5944: 5941: 5939: 5936: 5934: 5931: 5929: 5926: 5923: 5919: 5918:niflumic acid 5915: 5911: 5907: 5904: 5902: 5899: 5897: 5894: 5892: 5889: 5887: 5884: 5881: 5877: 5873: 5869: 5865: 5862: 5860: 5857: 5855: 5852: 5850: 5847: 5845: 5844:Clomethiazole 5842: 5840: 5839:Chlormezanone 5837: 5835: 5832: 5830: 5829:Carbamazepine 5827: 5824: 5820: 5816: 5812: 5809: 5806: 5802: 5799: 5797: 5794: 5792: 5789: 5787: 5784: 5782: 5779: 5778: 5776: 5772: 5766: 5763: 5761: 5758: 5756: 5753: 5751: 5748: 5746: 5743: 5741: 5738: 5736: 5733: 5731: 5728: 5726: 5723: 5721: 5718: 5716: 5713: 5711: 5708: 5706: 5705:Nitrous oxide 5703: 5701: 5698: 5696: 5693: 5691: 5688: 5686: 5683: 5681: 5678: 5676: 5673: 5671: 5668: 5666: 5663: 5661: 5658: 5656: 5653: 5651: 5648: 5646: 5643: 5641: 5638: 5636: 5635:Diethyl ether 5633: 5631: 5628: 5626: 5623: 5621: 5618: 5616: 5613: 5611: 5608: 5606: 5603: 5601: 5598: 5596: 5593: 5591: 5588: 5586: 5583: 5581: 5578: 5576: 5573: 5571: 5568: 5566: 5563: 5561: 5558: 5556: 5553: 5552: 5550: 5548: 5544: 5540: 5534: 5531: 5529: 5526: 5524: 5521: 5519: 5516: 5514: 5511: 5509: 5506: 5504: 5501: 5499: 5496: 5494: 5491: 5489: 5486: 5485: 5483: 5481: 5477: 5471: 5468: 5466: 5463: 5461: 5458: 5456: 5453: 5452: 5450: 5448: 5444: 5438: 5437:Pyrithyldione 5435: 5433: 5430: 5428: 5425: 5423: 5420: 5419: 5417: 5415: 5411: 5405: 5402: 5400: 5397: 5395: 5392: 5391: 5389: 5387: 5383: 5377: 5374: 5372: 5369: 5367: 5364: 5362: 5359: 5357: 5354: 5352: 5349: 5347: 5344: 5342: 5339: 5337: 5334: 5332: 5329: 5327: 5324: 5322: 5319: 5317: 5314: 5312: 5309: 5307: 5304: 5302: 5299: 5297: 5294: 5292: 5289: 5287: 5284: 5282: 5279: 5277: 5274: 5272: 5269: 5267: 5264: 5262: 5259: 5257: 5254: 5252: 5249: 5247: 5244: 5242: 5239: 5237: 5234: 5232: 5228: 5225: 5224: 5221: 5218: 5216: 5213: 5211: 5208: 5206: 5203: 5201: 5198: 5196: 5193: 5191: 5188: 5186: 5182: 5181: 5177: 5176: 5173: 5170: 5168: 5165: 5163: 5160: 5158: 5155: 5153: 5149: 5148: 5144: 5143: 5140: 5137: 5135: 5132: 5130: 5127: 5125: 5122: 5120: 5117: 5115: 5111: 5110: 5106: 5105: 5103: 5101: 5097: 5091: 5088: 5086: 5083: 5081: 5078: 5076: 5073: 5071: 5068: 5066: 5063: 5061: 5058: 5056: 5053: 5051: 5048: 5046: 5043: 5041: 5038: 5036: 5033: 5031: 5028: 5026: 5023: 5021: 5018: 5016: 5013: 5011: 5008: 5006: 5003: 5001: 4998: 4996: 4993: 4991: 4988: 4986: 4983: 4981: 4978: 4976: 4973: 4971: 4968: 4966: 4962: 4960: 4957: 4955: 4952: 4950: 4947: 4945: 4942: 4940: 4937: 4935: 4932: 4930: 4927: 4926: 4924: 4922: 4918: 4912: 4909: 4907: 4904: 4902: 4899: 4897: 4894: 4892: 4889: 4887: 4884: 4883: 4881: 4879: 4875: 4869: 4866: 4864: 4861: 4859: 4856: 4854: 4851: 4849: 4846: 4844: 4841: 4839: 4836: 4834: 4831: 4829: 4826: 4824: 4821: 4819: 4816: 4814: 4811: 4809: 4806: 4804: 4801: 4799: 4796: 4795: 4793: 4790: 4786: 4780: 4777: 4775: 4772: 4770: 4767: 4766: 4764: 4762: 4758: 4752: 4749: 4746: 4742: 4739: 4737: 4734: 4732: 4729: 4727: 4724: 4722: 4719: 4717: 4714: 4712: 4709: 4707: 4704: 4702: 4699: 4697: 4694: 4692: 4689: 4687: 4684: 4682: 4679: 4678: 4676: 4674: 4670: 4664: 4661: 4659: 4656: 4654: 4651: 4649: 4646: 4644: 4643:Phenprobamate 4641: 4639: 4636: 4634: 4631: 4629: 4626: 4624: 4621: 4619: 4616: 4614: 4611: 4609: 4608:Hexapropymate 4606: 4604: 4601: 4599: 4596: 4594: 4591: 4589: 4586: 4584: 4583:Difebarbamate 4581: 4579: 4576: 4574: 4571: 4569: 4566: 4564: 4561: 4560: 4558: 4556: 4552: 4546: 4543: 4541: 4538: 4536: 4533: 4531: 4528: 4526: 4523: 4521: 4518: 4516: 4513: 4511: 4508: 4506: 4503: 4501: 4498: 4496: 4493: 4491: 4488: 4486: 4483: 4481: 4478: 4476: 4473: 4471: 4468: 4466: 4463: 4461: 4458: 4456: 4453: 4451: 4448: 4446: 4443: 4441: 4438: 4436: 4433: 4431: 4428: 4426: 4423: 4421: 4418: 4416: 4413: 4411: 4408: 4406: 4403: 4401: 4398: 4396: 4395:Nortetrazepam 4393: 4391: 4388: 4386: 4383: 4381: 4378: 4376: 4373: 4371: 4368: 4366: 4363: 4361: 4358: 4356: 4353: 4351: 4348: 4346: 4343: 4341: 4338: 4336: 4333: 4331: 4328: 4326: 4323: 4321: 4318: 4316: 4313: 4311: 4308: 4306: 4303: 4301: 4298: 4296: 4293: 4291: 4288: 4286: 4283: 4281: 4278: 4276: 4273: 4271: 4268: 4266: 4263: 4261: 4258: 4256: 4255:Flutoprazepam 4253: 4251: 4248: 4246: 4243: 4241: 4238: 4236: 4235:Flunitrazolam 4233: 4231: 4230:Flunitrazepam 4228: 4226: 4223: 4221: 4220:Flubromazolam 4218: 4216: 4215:Flubromazepam 4213: 4211: 4208: 4206: 4203: 4201: 4198: 4196: 4193: 4191: 4188: 4186: 4183: 4181: 4178: 4176: 4173: 4171: 4168: 4166: 4163: 4161: 4158: 4156: 4153: 4151: 4148: 4146: 4143: 4141: 4138: 4136: 4133: 4131: 4128: 4126: 4123: 4121: 4118: 4116: 4115:Cloniprazepam 4113: 4111: 4108: 4106: 4103: 4101: 4098: 4096: 4093: 4091: 4088: 4086: 4083: 4081: 4078: 4076: 4073: 4071: 4068: 4066: 4063: 4061: 4058: 4056: 4053: 4051: 4048: 4046: 4043: 4041: 4038: 4036: 4033: 4031: 4028: 4026: 4023: 4021: 4018: 4016: 4013: 4011: 4008: 4006: 4005:2-Oxoquazepam 4003: 4002: 4000: 3998: 3994: 3988: 3985: 3983: 3980: 3978: 3975: 3973: 3970: 3968: 3965: 3963: 3960: 3958: 3955: 3953: 3950: 3948: 3947:Thialbarbital 3945: 3943: 3942:Tetrabarbital 3940: 3938: 3935: 3933: 3930: 3928: 3927:Spirobarbital 3925: 3923: 3920: 3918: 3915: 3913: 3910: 3908: 3907:Proxibarbital 3905: 3903: 3900: 3898: 3897:Propallylonal 3895: 3893: 3890: 3888: 3885: 3883: 3880: 3878: 3877:Phenobarbital 3875: 3873: 3870: 3868: 3867:Pentobarbital 3865: 3863: 3860: 3858: 3857:Narcobarbital 3855: 3853: 3850: 3848: 3845: 3843: 3840: 3838: 3835: 3833: 3830: 3828: 3825: 3823: 3822:Heptobarbital 3820: 3818: 3815: 3813: 3810: 3808: 3805: 3803: 3800: 3798: 3795: 3793: 3792:Difebarbamate 3790: 3788: 3785: 3783: 3782:Cyclobarbital 3780: 3778: 3775: 3773: 3770: 3768: 3765: 3763: 3760: 3758: 3755: 3753: 3750: 3748: 3745: 3743: 3740: 3738: 3735: 3733: 3730: 3728: 3727:Benzobarbital 3725: 3723: 3720: 3718: 3715: 3713: 3710: 3708: 3705: 3703: 3700: 3698: 3695: 3693: 3690: 3689: 3687: 3685: 3681: 3675: 3672: 3670: 3667: 3665: 3662: 3660: 3657: 3655: 3653: 3649: 3647: 3645: 3641: 3639: 3636: 3634: 3631: 3629: 3626: 3624: 3621: 3619: 3616: 3614: 3611: 3609: 3606: 3604: 3601: 3599: 3598:Ethchlorvynol 3596: 3593: 3589: 3586: 3584: 3581: 3579: 3576: 3574: 3571: 3569: 3566: 3565: 3563: 3561: 3557: 3553: 3540: 3535: 3533: 3528: 3526: 3521: 3520: 3517: 3505: 3502: 3500: 3497: 3495: 3492: 3490: 3487: 3485: 3482: 3479: 3475: 3472: 3470: 3467: 3463: 3462:Methocarbamol 3460: 3458: 3455: 3453: 3452:Mephenoxalone 3450: 3448: 3445: 3443: 3442:Chlorphenesin 3440: 3439: 3438: 3434: 3431: 3429: 3426: 3424: 3421: 3419: 3416: 3412: 3411:Phenaglycodol 3409: 3407: 3404: 3402: 3399: 3398: 3397: 3394: 3390: 3387: 3386: 3385: 3382: 3381: 3379: 3375: 3369: 3366: 3364: 3361: 3359: 3356: 3354: 3351: 3349: 3346: 3345: 3343: 3341: 3328: 3322: 3319: 3317: 3314: 3312: 3309: 3308: 3306: 3304: 3300: 3294: 3291: 3289: 3286: 3284: 3281: 3279: 3276: 3275: 3273: 3271: 3267: 3257: 3254: 3253: 3251: 3247: 3238: 3235: 3233: 3230: 3228: 3225: 3224: 3223: 3220: 3215: 3212: 3210: 3207: 3206: 3205: 3202: 3201: 3199: 3197: 3193: 3184: 3181: 3179: 3176: 3175: 3174: 3171: 3166: 3163: 3161: 3158: 3156: 3155:Amitriptyline 3153: 3152: 3151: 3148: 3146: 3143: 3142: 3140: 3138: 3134: 3131: 3129: 3122: 3116: 3113: 3111: 3108: 3106: 3103: 3101: 3098: 3096: 3093: 3091: 3088: 3086: 3083: 3081: 3078: 3077: 3075: 3073: 3065: 3052: 3049: 3047: 3044: 3042: 3039: 3038: 3037: 3034: 3029: 3026: 3024: 3021: 3020: 3019: 3016: 3015: 3013: 3011: 3007: 2998: 2995: 2993: 2990: 2989: 2988: 2985: 2980: 2977: 2975: 2972: 2970: 2969:Amitriptyline 2967: 2966: 2965: 2962: 2958: 2955: 2953: 2950: 2948: 2945: 2944: 2943: 2940: 2939: 2937: 2935: 2931: 2925: 2922: 2920: 2917: 2915: 2912: 2910: 2907: 2905: 2904:Methapyrilene 2902: 2900: 2897: 2895: 2892: 2890: 2887: 2885: 2882: 2880: 2877: 2876: 2874: 2872: 2868: 2865: 2863: 2856: 2850: 2847: 2845: 2842: 2840: 2837: 2835: 2832: 2829: 2825: 2822: 2820: 2817: 2815: 2812: 2810: 2809:Aceburic acid 2807: 2805: 2802: 2800: 2797: 2796: 2794: 2792: 2785: 2773: 2770: 2768: 2765: 2763: 2762:Isovaleramide 2760: 2759: 2758: 2757:Sesquiterpene 2755: 2753: 2750: 2746: 2743: 2741: 2738: 2736: 2733: 2732: 2731: 2728: 2726: 2723: 2721: 2718: 2716: 2713: 2711: 2708: 2706: 2703: 2701: 2698: 2696: 2695:Clomethiazole 2693: 2691: 2688: 2686: 2683: 2681: 2678: 2676: 2673: 2669: 2666: 2664: 2661: 2659: 2656: 2655: 2653: 2650: 2648: 2645: 2643: 2640: 2639: 2637: 2633: 2627: 2624: 2622: 2619: 2617: 2614: 2612: 2609: 2607: 2604: 2602: 2599: 2597: 2594: 2592: 2589: 2587: 2584: 2582: 2579: 2578: 2576: 2574: 2570: 2564: 2561: 2559: 2558:Pyrithyldione 2556: 2554: 2551: 2549: 2546: 2545: 2543: 2541: 2537: 2531: 2528: 2527: 2525: 2523: 2519: 2513: 2510: 2508: 2505: 2503: 2500: 2498: 2495: 2493: 2490: 2488: 2485: 2483: 2480: 2478: 2475: 2473: 2470: 2468: 2465: 2463: 2460: 2459: 2457: 2455: 2451: 2445: 2442: 2440: 2437: 2435: 2432: 2430: 2427: 2425: 2422: 2420: 2417: 2415: 2412: 2410: 2407: 2406: 2404: 2402: 2398: 2392: 2389: 2387: 2384: 2382: 2379: 2377: 2374: 2372: 2369: 2367: 2364: 2363: 2361: 2359: 2355: 2349: 2346: 2344: 2341: 2339: 2336: 2335: 2333: 2331: 2327: 2321: 2318: 2316: 2313: 2311: 2310:Phenprobamate 2308: 2306: 2305:Methocarbamol 2303: 2301: 2298: 2296: 2295:Hexapropymate 2293: 2291: 2288: 2286: 2283: 2281: 2278: 2277: 2275: 2273: 2269: 2263: 2260: 2258: 2255: 2253: 2250: 2248: 2245: 2243: 2240: 2238: 2235: 2233: 2230: 2228: 2225: 2223: 2220: 2218: 2215: 2213: 2212:Flutoprazepam 2210: 2208: 2205: 2203: 2200: 2198: 2197:Flunitrazepam 2195: 2193: 2192:Flunitrazolam 2190: 2188: 2187:Flubromazolam 2185: 2183: 2180: 2178: 2175: 2173: 2170: 2168: 2165: 2163: 2160: 2158: 2155: 2154: 2152: 2150: 2146: 2140: 2137: 2135: 2132: 2130: 2127: 2125: 2122: 2120: 2117: 2115: 2112: 2110: 2107: 2105: 2102: 2100: 2097: 2095: 2092: 2090: 2089:Phenobarbital 2087: 2085: 2082: 2080: 2079:Pentobarbital 2077: 2075: 2074:Narcobarbital 2072: 2070: 2067: 2065: 2064:Mephobarbital 2062: 2060: 2057: 2055: 2052: 2050: 2047: 2045: 2044:Cyclobarbital 2042: 2040: 2037: 2035: 2032: 2030: 2027: 2025: 2022: 2020: 2017: 2015: 2012: 2011: 2009: 2007: 2003: 1997: 1994: 1992: 1989: 1987: 1986:Ethchlorvynol 1984: 1982: 1979: 1977: 1974: 1972: 1969: 1967: 1964: 1963: 1961: 1959: 1955: 1952: 1950: 1943: 1938: 1934: 1930: 1923: 1918: 1916: 1911: 1909: 1904: 1903: 1900: 1893: 1890: 1887: 1883: 1880: 1877: 1876: 1863: 1859: 1852: 1844: 1840: 1833: 1825: 1821: 1816: 1811: 1807: 1803: 1799: 1792: 1781: 1774: 1768: 1760: 1756: 1752: 1748: 1743: 1738: 1734: 1730: 1726: 1719: 1711: 1707: 1700: 1692: 1688: 1684: 1677: 1669: 1662: 1654: 1648: 1640: 1636: 1632: 1626: 1622: 1621: 1613: 1605: 1601: 1597: 1591: 1583: 1579: 1575: 1571: 1567: 1563: 1559: 1555: 1548: 1540: 1536: 1532: 1528: 1524: 1520: 1513: 1505: 1501: 1496: 1491: 1487: 1483: 1479: 1475: 1471: 1464: 1456: 1452: 1448: 1444: 1439: 1434: 1430: 1426: 1422: 1415: 1407: 1403: 1398: 1393: 1389: 1385: 1381: 1374: 1372: 1370: 1361: 1355: 1340: 1336: 1335:www.drugs.com 1332: 1326: 1324: 1308: 1304: 1300: 1294: 1279: 1275: 1269: 1254: 1250: 1246: 1239: 1237: 1223: 1217: 1209: 1205: 1198: 1196: 1180: 1176: 1172: 1168: 1162: 1158: 1148: 1145: 1144: 1138: 1136: 1128: 1126: 1122: 1118: 1114: 1110: 1105: 1102: 1100: 1096: 1091: 1088: 1085:or 1 gram of 1084: 1080: 1079:pentobarbital 1076: 1072: 1062: 1060: 1056: 1052: 1048: 1044: 1039: 1037: 1033: 1029: 1026:, playwright 1025: 1021: 1020:Carole Landis 1017: 1016: 1011: 1006: 992: 989: 986: 983: 980: 977: 976: 975: 973: 959: 956: 954: 951: 948: 947: 946: 943: 940: 938: 935: 932: 930: 927: 924: 921: 918: 915: 913: 910: 906: 903: 900: 897: 896: 894: 892: 889: 888: 887: 876: 858: 855: 854: 853: 845: 842: 837: 835: 831: 827: 823: 819: 811: 799: 795: 791: 789: 785: 783: 780:Treatment of 779: 778: 777: 769: 766: 762: 758: 754: 750: 746: 742: 738: 734: 730: 726: 722: 712: 705: 696: 691: 690: 687: 680: 671: 670: 667: 660: 653: 649: 648: 646: 643: 638: 631: 629: 625: 598: 596: 592: 587: 583: 579: 576: 574: 572:ECHA InfoCard 568: 560: 556: 555:DTXSID6044145 552: 551: 549: 540: 536: 529: 525: 524: 522: 520: 516: 509: 505: 504: 502: 500: 496: 489: 485: 484: 482: 480: 476: 469: 465: 464: 462: 460: 456: 449: 445: 444: 442: 440: 436: 429: 425: 424: 422: 420: 416: 409: 405: 404: 402: 400: 396: 389: 385: 384: 382: 375: 371: 364: 360: 359: 357: 355: 351: 343: 338: 337: 334: 327: 322: 319: 316: 314: 310: 306: 304: 297: 294: 291: 289: 285: 281: 279: 275: 271: 269: 265: 261: 257: 251: 241: 238: 228: 226: 216: 213: 204: 202: 193: 190: 180: 179: 177: 175: 171: 166: 158: 153: 148: 143: 140: 139: 137: 135: 131: 127: 125: 119: 112: 111: 109: 107: 101: 97: 93: 91: 87: 83: 79: 77: 73: 69: 65: 63: 59: 56:Clinical data 54: 50: 45: 41: 36: 19: 6163:Barbiturates 6126: 6125: 6096: 5953:Lavender oil 5695:Nitric oxide 5615:Cryofluorane 5560:Acetophenone 5518:Methaqualone 5513:Mecloqualone 5508:Mebroqualone 5498:Diproqualone 5493:Cloroqualone 5422:Glutethimide 5226: 5178: 5145: 5107: 5080:Testosterone 5045:Progesterone 5010:Hydroxydione 4959:Androsterone 4886:Acecarbromal 4791:constituents 4578:Cyclarbamate 4568:Carisoprodol 4340:Metaclazepam 4335:Menitrazepam 4325:Meclonazepam 4320:Lormetazepam 4250:Flutemazepam 4075:Ciclotizolam 4065:Carburazepam 3957:Thiobarbital 3917:Secobarbital 3916: 3882:Phetharbital 3862:Nealbarbital 3847:Methohexital 3832:Hexobarbital 3767:Butallylonal 3762:Butobarbital 3717:Barbexaclone 3712:Aprobarbital 3697:Allobarbital 3684:Barbiturates 3651: 3643: 3633:Petrichloral 3504:Valnoctamide 3406:Metaglycodol 3401:Fenpentadiol 3311:Daridorexant 3214:Thioridazine 3165:Trimipramine 3100:Medetomidine 3028:Thioridazine 2979:Trimipramine 2924:Propiomazine 2919:Promethazine 2725:Petrichloral 2710:Kavalactones 2642:Acetophenone 2611:Methaqualone 2606:Mecloqualone 2601:Mebroqualone 2591:Diproqualone 2586:Cloroqualone 2548:Glutethimide 2444:Progesterone 2434:Hydroxydione 2366:Acecarbromal 2280:Carisoprodol 2222:Lormetazepam 2207:Flutemazepam 2109:Secobarbital 2108: 2069:Methohexital 2059:Hexobarbital 2039:Butobarbital 2034:Butabarbital 2024:Aprobarbital 2014:Allobarbital 2006:Barbiturates 1851: 1842: 1832: 1805: 1801: 1791: 1767: 1732: 1728: 1718: 1709: 1699: 1686: 1676: 1667: 1661: 1619: 1612: 1600:The Guardian 1599: 1590: 1560:(1): 21–30. 1557: 1553: 1547: 1522: 1518: 1512: 1477: 1473: 1463: 1428: 1424: 1414: 1387: 1383: 1354: 1343:. Retrieved 1334: 1311:. Retrieved 1302: 1293: 1282:. Retrieved 1268: 1257:. Retrieved 1248: 1216: 1183:. Retrieved 1161: 1129: 1106: 1103: 1092: 1068: 1040: 1036:Fred Hampton 1024:Judy Garland 1013: 1001: 969: 885: 882:Side effects 851: 838: 816: 805:Availability 775: 760: 732: 721:Secobarbital 720: 719: 708:   341: 300:Elimination 174:Legal status 168:Legal status 32:Secobarbital 6035:Stiripentol 6030:Seproxetine 6000:Niacinamide 5980:Loreclezole 5801:Avermectins 5765:Vinyl ether 5735:Sevoflurane 5715:Paraldehyde 5665:Halopropane 5488:Afloqualone 5470:Tracazolate 5465:ICI-190,622 5455:Cartazolate 5432:Piperidione 5427:Methyprylon 5394:Fospropofol 5316:Pipequaline 5124:Pazinaclone 5114:Eszopiclone 4970:Cholesterol 4954:Androstenol 4878:Monoureides 4858:Methysticin 4658:Tetrabamate 4638:Pentabamate 4628:Meprobamate 4598:Febarbamate 4563:Carisbamate 4515:Triflubazam 4505:Tolufazepam 4465:Rilmazafone 4460:Remimazolam 4435:Proflazepam 4420:Pivoxazepam 4380:Nitrazepate 4370:Nimetazepam 4305:Lopirazepam 4275:Haloxazolam 4225:Fludiazepam 4170:Doxefazepam 4145:Delorazepam 4125:Clotiazepam 4120:Clorazepate 4085:Cinolazepam 3982:Vinbarbital 3937:Tetrabamate 3892:Probarbital 3872:Phenallymal 3837:Metharbital 3812:Febarbamate 3707:Amobarbital 3608:Isopropanol 3578:Chloralodol 3489:Scopolamine 3433:Guaifenesin 3428:Fenadiazole 3384:Cannabidiol 3358:Mirogabalin 3316:Lemborexant 3293:Tasimelteon 3278:Agomelatine 3237:Risperidone 3183:Mirtazapine 3072:-Adrenergic 3051:Risperidone 2997:Mirtazapine 2947:Etoperidone 2914:Pheniramine 2899:Hydroxyzine 2720:Paraldehyde 2715:Loreclezole 2581:Afloqualone 2563:Piperidione 2553:Methyprylon 2482:Pazinaclone 2462:Eszopiclone 2424:Alphaxolone 2419:Alphadolone 2358:Monoureides 2300:Meprobamate 2237:Nitemazepam 2232:Nimetazepam 2177:Doxefazepam 2162:Cinolazepam 2134:Vinbarbital 2099:Proxibarbal 2084:Phenallymal 2019:Amobarbital 1971:Chloralodol 1202:Lexi-Comp. 1115:, used for 1071:Netherlands 834:hygroscopic 830:sodium salt 794:anaesthesia 772:Indications 741:anaesthetic 737:barbiturate 725:sodium salt 635: g·mol 578:100.000.894 324:Identifiers 307:15-40 hours 237:Schedule II 201:Schedule IV 90:MedlinePlus 62:Trade names 6152:Categories 6068:Topiramate 6058:Terpenoids 6015:Propanidid 6005:Org 25,435 5933:Flupirtine 5928:Fluoxetine 5834:Chloralose 5805:ivermectin 5710:Norflurane 5675:Isoflurane 5620:Desflurane 5610:Chloroform 5570:Aliflurane 5503:Etaqualone 5331:SB-205,384 5261:CP-615,003 5256:CL-218,872 5210:Panadiplon 5200:Lorediplon 5129:Suproclone 5090:Zuranolone 5050:Renanolone 5035:Posovolone 5015:Minaxolone 5005:Ganaxolone 4944:Alfaxalone 4939:Alfadolone 4929:Acebrochol 4896:Bromisoval 4774:Metomidate 4761:Imidazoles 4721:Hispidulin 4673:Flavonoids 4633:Nisobamate 4623:Mebutamate 4593:Ethinamate 4588:Emylcamate 4555:Carbamates 4525:Tuclazepam 4500:Tetrazepam 4455:Reclazepam 4430:Premazepam 4410:Phenazepam 4390:Nordazepam 4385:Nitrazolam 4375:Nitrazepam 4355:Motrazepam 4310:Loprazolam 4300:Lofendazam 4285:Imidazenil 4245:Flutazolam 4240:Flurazepam 4210:Fletazepam 4165:Dimdazenil 4160:Diclazepam 4140:Cyprazepam 4130:Cloxazolam 4110:Clonazolam 4105:Clonazepam 4095:Climazolam 4055:Brotizolam 4050:Bromazolam 4045:Bromazepam 4040:Bretazenil 4035:Bentazepam 4025:Arfendazam 4020:Alprazolam 4015:Adinazolam 3987:Vinylbital 3967:Thiopental 3842:Methitural 3757:Buthalital 3752:Butalbital 3603:Isobutanol 3457:Metaxalone 3447:Mephenesin 3368:Pregabalin 3348:Gabapentin 3321:Suvorexant 3256:Niaprazine 3232:Quetiapine 3227:Olanzapine 3110:Tizanidine 3105:Romifidine 3095:Lofexidine 3085:Detomidine 3046:Quetiapine 3041:Olanzapine 2952:Nefazodone 2894:Doxylamine 2879:Captodiame 2690:Chloralose 2654:compounds 2596:Etaqualone 2492:Suproclone 2472:Lirequinil 2439:Minaxolone 2429:Eltanolone 2409:Acebrochol 2376:Bromisoval 2343:Metomidate 2330:Imidazoles 2290:Ethinamate 2285:Emylcamate 2272:Carbamates 2247:Nitrazolam 2242:Nitrazepam 2217:Loprazolam 2202:Flurazepam 2172:Clonazolam 2167:Climazolam 2157:Brotizolam 2139:Vinylbital 2124:Thiopental 1345:2016-03-24 1313:2016-03-24 1284:2014-03-05 1259:2016-03-24 1185:2023-08-16 1153:References 1117:euthanasia 1109:veterinary 1083:thiopental 1075:euthanasia 972:Withdrawal 966:Withdrawal 937:Nightmares 891:Somnolence 798:anxiolysis 749:anxiolytic 640:3D model ( 628:Molar mass 508:CHEBI:9073 468:1P7H87IN75 439:ChemSpider 399:IUPHAR/BPS 354:CAS Number 333:IUPAC name 288:Metabolism 212:Anlage III 6127:See also: 6089:valerenol 6010:Phenytoin 5990:Monastrol 5948:Lanthanum 5943:KRM-II-81 5906:Fenamates 5901:Etifoxine 5896:Etazepine 5891:Efavirenz 5849:Darigabat 5745:Teflurane 5730:Roflurane 5725:Propylene 5670:Halothane 5655:Fluroxene 5640:Enflurane 5543:Volatiles 5460:Etazolate 5371:Viqualine 5326:RWJ-51204 5291:L-838,417 5281:Imepitoin 5251:CGS-20625 5246:CGS-13767 5231:Adipiplon 5205:Ocinaplon 5167:Saripidem 5162:Necopidem 5139:Zopiclone 5134:Suriclone 5119:Pagoclone 5025:ORG-21465 5020:ORG-20599 4911:Ectylurea 4901:Carbromal 4779:Propoxate 4769:Etomidate 4696:Baicalein 4653:Styramate 4648:Procymate 4618:Lorbamate 4603:Felbamate 4573:Clocental 4545:Zomebazam 4540:Zolazepam 4535:Zapizolam 4530:Uldazepam 4510:Triazolam 4495:Temazepam 4490:Sulazepam 4480:Ro48-8684 4475:Ro48-6791 4470:Ripazepam 4440:Pyrazolam 4415:Pinazepam 4365:Nifoxipam 4350:Midazolam 4345:Mexazolam 4330:Medazepam 4315:Lorazepam 4295:Ketazolam 4290:Irazepine 4280:Iclazepam 4270:Halazepam 4265:Gidazepam 4260:Fosazepam 4180:Estazolam 4175:Elfazepam 4150:Demoxepam 4080:Cinazepam 4060:Camazepam 4030:Avizafone 3952:Thiamylal 3887:Primidone 3817:Heptabarb 3807:Eterobarb 3772:Carbubarb 3669:Triclofos 3568:Brometone 3494:Trazodone 3435:-related 3288:Ramelteon 3283:Melatonin 3270:Melatonin 3178:Mianserin 3145:Trazodone 3080:Clonidine 2992:Mianserin 2957:Trazodone 2909:Perlapine 2752:Triclofos 2705:Gaboxadol 2512:Zopiclone 2497:Suriclone 2487:Saripidem 2477:Necopidem 2391:Ectylurea 2386:Carbromal 2348:Propoxate 2338:Etomidate 2315:Procymate 2262:Triazolam 2257:Temazepam 2227:Midazolam 2182:Estazolam 2119:Thiamylal 2054:Heptabarb 1933:sedatives 1929:Hypnotics 1647:cite book 1639:957772989 1554:Epilepsia 1051:Thorazine 1043:Jonestown 1012:'s novel 958:Urticaria 916:Confusion 905:Dizziness 528:ChEMBL447 313:Excretion 302:half-life 122:Routes of 104:Pregnancy 76:Drugs.com 6115:TCS-1205 6110:TCS-1105 6100:α-Pinene 6073:Valerian 6048:tetronal 6025:Safranal 5974:obovatol 5970:magnolol 5966:honokiol 5796:Alogabat 5791:AA-29504 5740:Synthane 5700:Nitrogen 5680:Kerosine 5660:Gasoline 5650:Ethylene 5590:Centalun 5585:Butylene 5399:Propofol 5361:U-89843A 5341:TGSC01AA 5311:NS-11394 5276:GBLD-345 5241:CGS-9896 5236:CGS-8216 5220:Zaleplon 5215:Taniplon 5195:Indiplon 5190:Fasiplon 5185:Divaplon 5172:Zolpidem 5075:SAGE-872 5070:SAGE-689 5065:SAGE-516 5060:SAGE-324 5055:SAGE-105 4963:Certain 4906:Capuride 4868:Yangonin 4745:baicalin 4741:Skullcap 4731:Luteolin 4706:Catechin 4701:Baicalin 4691:Apigenin 4663:Tybamate 4450:Quazepam 4445:QH-II-66 4425:Prazepam 4405:Oxazolam 4400:Oxazepam 4200:Etizolam 4155:Diazepam 4135:CP-1414S 4100:Clobazam 4090:Clazolam 3977:Valofane 3932:Talbutal 3922:Sigmodal 3827:Hexethal 3722:Barbital 3702:Alphenal 3692:(-)-DMBB 3638:Propanol 3628:Pentanol 3618:Methanol 3560:Alcohols 3478:morphine 3469:Midaflur 3389:Cannabis 3363:Phenibut 3115:Xylazine 2844:Phenibut 2814:Baclofen 2740:Tetronal 2675:Centalun 2530:Propofol 2507:Zolpidem 2502:Zaleplon 2467:Indiplon 2381:Capuride 2320:Tybamate 2252:Quazepam 2114:Talbutal 2029:Barbital 1958:Alcohols 1882:Archived 1862:Archived 1824:12621146 1780:Archived 1759:23013621 1751:23574120 1691:Archived 1687:Oncoline 1604:Archived 1582:38785409 1539:13491317 1455:37714069 1339:Archived 1307:Archived 1278:Archived 1253:Archived 1208:Archived 1179:Archived 1141:See also 1113:Somulose 1087:propofol 987:Seizures 981:Insomnia 933:Vomiting 922:Headache 788:insomnia 782:epilepsy 757:hypnotic 753:sedative 723:(as the 711:(verify) 419:DrugBank 189:Class B1 152:QN51AA02 134:ATC code 106:category 6062:borneol 6060:(e.g., 6052:trional 6042:(e.g., 5960:(e.g., 5958:Lignans 5908:(e.g., 5866:(e.g., 5811:Bromide 5803:(e.g., 5786:α-EMTBL 5750:Toluene 5720:Propane 5595:Chloral 5575:Benzene 5555:Acetone 5386:Phenols 5376:Y-23684 5366:U-90042 5351:TPA-023 5336:SX-3228 5321:ROD-188 5306:NS-2710 5301:NS-2664 5286:JM-1232 5271:ELB-139 5266:CTP-354 5152:Alpidem 4751:Wogonin 4726:Linarin 4205:FG-8205 3912:Reposal 3613:Menthol 3573:Butanol 3476:(e.g., 3474:Opioids 3423:Evoxine 3160:Doxepin 2974:Doxepin 2849:Tolibut 2745:Trional 2652:Bromide 2522:Phenols 2104:Reposal 1574:5339251 1504:5448377 1495:2467013 1447:3521843 1406:5338884 1397:1935574 1069:In the 1059:Demerol 990:Tremors 978:Anxiety 912:Anxiety 733:Seconal 633:238.287 595:Formula 428:DB00418 374:PubChem 363:76-73-3 293:Hepatic 225:Class B 210:: 199:: 154: ( 150:) 144: ( 142:N05CA06 96:a682386 66:Seconal 18:Seconal 5995:Niacin 5580:Butane 5533:SL-164 5404:Thymol 5346:TP-003 5227:Others 5030:P1-185 4990:5β-DHP 4985:5α-DHP 4980:3α-DHP 4828:Kavain 4736:Rc-OMe 3377:Others 3303:Orexin 3249:Others 3239:, etc. 3216:, etc. 3185:, etc. 3167:, etc. 3053:, etc. 3030:, etc. 2999:, etc. 2981:, etc. 2635:Others 2626:SL-164 1822:  1757:  1749:  1637:  1627:  1580:  1572:  1537:  1502:  1492:  1453:  1445:  1425:Cancer 1404:  1394:  1228:  1167:Anvisa 1147:Tuinal 1125:cattle 1121:horses 1055:Talwin 1047:Valium 929:Nausea 925:Hunger 839:While 755:, and 666:SMILES 519:ChEMBL 488:D00430 282:45-60% 248: 235: 223: 187: 5854:DEABL 5547:gases 5356:TP-13 5085:THDOC 4975:DHDOC 3499:UMB68 2819:GABOB 1856:NIH. 1783:(PDF) 1776:(PDF) 1755:S2CID 1578:S2CID 1451:S2CID 1111:drug 953:Edema 686:InChI 642:JSmol 499:ChEBI 318:Renal 5157:DS-1 4789:Kava 4716:EGCG 3652:tert 3644:tert 3547:GABA 3339:VDCC 3125:5-HT 2788:GABA 1966:2M2B 1946:GABA 1937:N05C 1820:PMID 1747:PMID 1653:link 1635:OCLC 1625:ISBN 1570:PMID 1535:PMID 1500:PMID 1443:PMID 1402:PMID 1130:The 1123:and 796:and 479:KEGG 459:UNII 448:5005 408:7615 388:5193 262:data 128:Oral 72:AHFS 5886:DS2 4995:DHT 4711:EGC 2839:GVL 2834:GBL 2824:GHB 1843:CBC 1810:doi 1806:348 1737:doi 1733:368 1562:doi 1527:doi 1523:166 1490:PMC 1482:doi 1433:doi 1392:PMC 1249:NPR 1119:of 871:NaO 544:EPA 378:CID 157:WHO 147:WHO 6154:: 6136:• 6132:• 6087:, 6083:, 6079:, 6050:, 6046:, 5972:, 5968:, 5964:, 5920:, 5916:, 5912:, 5878:, 5874:, 5870:, 5821:, 5817:, 5229:: 5183:: 5150:: 5112:: 3127:2A 1860:. 1841:. 1818:. 1804:. 1800:. 1753:. 1745:. 1731:. 1727:. 1708:. 1689:. 1685:. 1649:}} 1645:{{ 1633:. 1598:. 1576:. 1568:. 1556:. 1533:. 1521:. 1498:. 1488:. 1478:46 1476:. 1472:. 1449:. 1441:. 1429:58 1427:. 1423:. 1400:. 1388:95 1386:. 1382:. 1368:^ 1337:. 1333:. 1322:^ 1305:. 1301:. 1251:. 1247:. 1235:^ 1206:. 1194:^ 1134:50 1132:LD 1127:. 1057:, 1053:, 1049:, 1022:, 865:18 861:12 751:, 747:, 743:, 609:18 603:12 342:RS 244:UN 231:US 219:UK 207:DE 196:CA 183:BR 6091:) 6064:) 6054:) 5976:) 5924:) 5882:) 5825:) 5807:) 5545:/ 4747:) 3594:) 3590:( 3550:A 3538:e 3531:t 3524:v 3480:) 3336:δ 3334:2 3332:α 3070:2 3068:α 2861:1 2859:H 2830:) 2826:( 2790:B 1948:A 1939:) 1935:( 1931:/ 1921:e 1914:t 1907:v 1845:. 1826:. 1812:: 1761:. 1739:: 1712:. 1670:. 1655:) 1641:. 1584:. 1564:: 1558:8 1541:. 1529:: 1506:. 1484:: 1457:. 1435:: 1408:. 1362:. 1348:. 1316:. 1287:. 1262:. 1188:. 873:3 869:2 867:N 863:H 644:) 621:3 618:O 615:2 612:N 606:H 600:C 546:) 542:( 340:( 272:? 246:: 233:: 221:: 185:: 160:) 74:/ 20:)

Index

Seconal


Trade names
AHFS
Drugs.com
Consumer Drug Information
MedlinePlus
a682386
Pregnancy
category

Routes of
administration

ATC code
N05CA06
WHO
QN51AA02
WHO
Legal status
Class B1
Schedule IV
Anlage III
Class B
Schedule II
Psychotropic Schedule II
Pharmacokinetic
Bioavailability
Protein binding
Metabolism
Hepatic
Elimination half-life
Excretion

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