463:
427:
511:
611:
451:
475:
415:
439:
523:
499:
595:
45:
487:
2449:
2411:
842:
Physical therapy is usually recommended to prevent muscle atrophy and to regain muscle strength and range of motion. Many individuals with dermatomyositis may need a topical ointment, such as topical corticosteroids, for their skin disorder. They should wear high-protection sunscreen and protective
917:
The cutaneous manifestations of dermatomyositis may or may not improve with therapy in parallel with the improvement of the myositis. In some people, the weakness and rash resolve together. In others, the two are not linked, with one or the other being more challenging to control. Often, cutaneous
710:
The fifth criterion is what differentiates dermatomyositis from polymyositis; the diagnosis is considered definite for dermatomyositis if three of items 1 through 4 are present in addition to 5, probable with any two in addition to 5, and possible if just one is present in addition to 5.
806:
No cure for dermatomyositis is known, but the symptoms can be treated. Options include medication, physical therapy, exercise, heat therapy (including microwave and ultrasound), orthotics and assistive devices, and rest. The standard treatment for dermatomyositis is a
334:. It can occur around the eyes along with swelling, but also occurs on the upper chest or back what is called the "shawl" (around the neck) or "V-sign" above the breasts and may also occur on the face, upper arms, thighs, or hands. Another form the rash takes is called
404:
There are further complications possible with dermatomyositis. These complications include difficulty swallowing due to the muscles in the esophagus being affected which can result in malnutrition and can cause the breathing of food or liquids, into the lungs.
301:
About one per 100,000 people per year are newly affected. The condition usually occurs in those in their 40s and 50s with women being affected more often than men. People of any age, however, may be affected. The condition was first described in the 1800s.
1603:
361:
If a person exhibits only skin findings characteristic of DM, without weakness or abnormal muscle enzymes, then he or she may be experiencing amyopathic dermatomyositis (ADM), formerly known as "dermatomyositis sine myositis".
763:
A given case of dermatomyositis may be classified as amyopathic dermatomyositis if only skin is affected and no muscle weakness for longer than 6 months is seen according to one 2016 review, or two years according to another.
2367:
2102:
Bernatsky S, Joseph L, Pineau CA, Belisle P, Boivin JF, Banerjee D, Clarke AE (July 2009). "Estimating the prevalence of polymyositis and dermatomyositis from administrative data: age, sex and regional differences".
2502:
2478:
237:
and worsening muscle weakness over time. These may occur suddenly or develop over months. Other symptoms may include weight loss, fever, lung inflammation, or light sensitivity. Complications may include
539:
374:
muscles (for example, the shoulders and thighs). Tasks that use these muscles: standing from sitting, lifting, and climbing stairs, can become increasingly difficult for people with dermatomyositis.
2262:
2415:
1599:
929:
Incidence of DM peaks at ages 40–50, but the disease can affect people of all ages. It tends to affect more women than men. The prevalence of DM ranges from one to 22 per 100,000 people.
603:
2614:
2385:
Ramos-E-Silva M, Pinto AP, Pirmez R, Cuzzi T, Carneiro SC (1 August 2016). "Dermatomyositis—Part 1: Definition, Epidemiology, Etiology and
Pathogenesis, and Clinics".
677:(testing of electric signalling in muscles), finding all three of: erratic, repetitive, high-frequency signals; short, low-energy signals between skeletal muscles and
2895:
1250:"Adult and juvenile dermatomyositis: are the distinct clinical features explained by our current understanding of serological subgroups and pathogenic mechanisms?"
1702:
Ramos-E-Silva M, Lima Pinto AP, Pirmez R, Cuzzi T, Carneiro S (1 October 2016). "Dermatomyositis-Part 2: Diagnosis, Association With
Malignancy, and Treatment".
696:
between the muscle cells, and finding abnormal muscle cell degeneration and regeneration, dying muscle cells, and muscle cells being consumed by other cells (
2426:
866:
As of 2016, treatments for amyopathic dermatomyositis in adults did not have a strong evidence base; published treatments included antimalarial medications,
2258:
571:. Between 18 and 25 per cent of people with amyopathic DM also have cancer. Malignancy in association with dermatomyositis is more prevalent after age 60.
3156:
2865:
2607:
722:(ANA). Around 80% of people with DM test positive for ANA and around 30% of people have myositis-specific autoantibodies which include antibodies to
1868:
1733:
2310:
2288:
1758:
Danieli MG, Gelardi C, Guerra F, Cardinaletti P, Pedini V, Gabrielli A (May 2016). "Cardiac involvement in polymyositis and dermatomyositis".
1492:
Callander J, Robson Y, Ingram J, Piguet V (11 May 2016). "Treatment of clinically amyopathic dermatomyositis in adults: a systematic review".
462:
3161:
2600:
1793:
Feldman BM, Rider LG, Reed AM, Pachman LM (June 2008). "Juvenile dermatomyositis and other idiopathic inflammatory myopathies of childhood".
1090:
426:
937:
The diagnostic criteria were proposed in 1975 and became widely adopted. Amyopathic DM, also called DM sine myositis, was named in 2002.
385:
In some people, the condition affects the lungs, and they may have a cough or difficulty breathing. If the disease affects the heart,
2345:
1177:
827:
can also improve recovery. Other immunosuppressive agents used to treat the inflammation associated with dermatomyositis include
3065:
2946:
2858:
2830:
2148:"Incidence of Dermatomyositis and Clinically Amyopathic Dermatomyositis: A Population-Based Study in Olmsted County, Minnesota"
510:
389:
may occur. If it affects the blood vessels in the stomach or intestines, which is more common in juvenile DM, the people might
2976:
1371:
450:
2928:
628:
The diagnosis of dermatomyositis is based on five criteria, which are also used to differentially diagnose with respect to
3146:
253:. Dermatomyositis may develop as a paraneoplastic syndrome associated with several forms of malignancy. It is a type of
2923:
347:
274:
Although no cure for the condition is known, treatments generally improve symptoms. Treatments may include medication,
2851:
2810:
2259:"Greek Reporter: 'Maria Callas did not kill herself from grief for Onassis, a rare disease cost her career and life'"
2040:
Tymms KE, Webb J (December 1985). "Dermatopolymyositis and other connective tissue diseases: a review of 105 cases".
1539:
474:
2647:
1199:
Tudorancea AD, Ciurea PL, Vreju AF, Turcu-Stiolica A, Gofita CE, Criveanu C, Musetescu AE, Dinescu SC (July 2021).
544:
The cause is unknown, but it may result from an initial viral infection or cancer, either of which could raise an
414:
3106:
3075:
3070:
2981:
2747:
2014:
2900:
2723:
843:
clothing. Surgery may be required to remove calcium deposits that cause nerve pain and recurrent infections.
298:
may also improve outcomes. Most people improve with treatment and in some, the condition resolves completely.
3037:
2652:
3166:
3151:
3141:
2991:
2639:
398:
351:
2420:
1933:
Wright NA, Vleugels RA, Callen JP (January 2016). "Cutaneous dermatomyositis in the era of biologicals".
1864:
1017:
898:. None appears to be very effective; among them, intravenous immunoglobulin has had the best outcomes.
739:
354:
may also be found over other bony prominences including the elbows, knees, or feet. All these rashes are
2815:
883:
824:
773:
749:
727:
723:
295:
17:
2624:
966:
731:
552:
343:
1729:
3116:
2689:
2517:
2314:
2284:
974:
795:
268:
Eighty percent of adults with adult-onset dermatomyositis have a myositis-specific antibody (MSA).
3080:
1989:
1082:
3047:
3032:
3004:
2874:
2698:
2223:
Bohan A, Peter JB (20 February 1975). "Polymyositis and
Dermatomyositis: (Second of Two Parts)".
788:
438:
271:
Sixty percent of children with juvenile dermatomyositis have a myositis-specific antibody (MSA).
155:
87:
2195:
Bohan A, Peter JB (13 February 1975). "Polymyositis and
Dermatomyositis: (First of Two Parts)".
2805:
2800:
875:
719:
660:
146:
2795:
2557:
1448:
Kuhn A, Landmann A, Bonsmann G (October 2016). "The skin in autoimmune diseases-Unmet needs".
2905:
2667:
2368:"'Dangal' actor Suhani Bhatnagar succumbs to dermatomyositis: Know about this rare condition"
1621:
1020:
gel (Phase IV, open label), IMO-8400, an antagonist of Toll-like receptor 7,8 and 9 (Ph II),
895:
780:
668:
254:
222:
2337:
706:
typical of dermatomyositis, which include heliotrope rash, Gottron sign, and
Gottron papules
3111:
3060:
3055:
2915:
2790:
2718:
1390:
Callen JP (June 2010). "Cutaneous
Manifestations of Dermatomyositis and Their Management".
1342:
Approximately 60% of patients with JDM are positive for a myositis-specific antibody (MSA).
1304:"Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care"
990:
743:
664:
1169:
8:
2971:
2956:
2680:
2506:
522:
2774:
1836:
1328:
1303:
921:
The risk of death from the condition is much higher if the heart or lungs are affected.
752:
may be useful to guide muscle biopsy and to investigate involvement of internal organs;
498:
3085:
3014:
2766:
2592:
2172:
2147:
2128:
1958:
1910:
1883:
1818:
1679:
1652:
1567:
1517:
1415:
1276:
1249:
1225:
1200:
1128:
1025:
906:
Before the advent of modern treatments such as prednisone, intravenous immunoglobulin,
850:
486:
327:
246:
77:
2511:
2080:
1806:
2951:
2528:
2394:
2240:
2212:
2177:
2120:
2084:
2049:
1950:
1915:
1822:
1810:
1775:
1711:
1684:
1633:
1559:
1509:
1465:
1407:
1367:
1333:
1281:
1230:
1132:
960:
335:
219:
129:
114:
65:
2132:
1600:"Polymyositis and Dermatomyositis – Musculoskeletal and Connective Tissue Disorders"
1571:
1521:
1419:
811:
drug, given either in pill form or intravenously. Immunosuppressant drugs, such as
2882:
2762:
2743:
2568:
2232:
2204:
2167:
2159:
2112:
2076:
1962:
1942:
1905:
1895:
1802:
1767:
1674:
1664:
1551:
1501:
1457:
1399:
1359:
1323:
1315:
1271:
1261:
1220:
1212:
1124:
996:
954:
871:
832:
674:
355:
275:
258:
170:
135:
2163:
2825:
2657:
2522:
2454:
1771:
1461:
984:
652:
648:
315:
283:
250:
187:
2236:
2208:
1363:
60:
in a person with juvenile dermatomyositis. These are known as
Gottron's papules.
2890:
2728:
2533:
1319:
1290:
Myositis-specific autoantibodies (MSAs) can now be identified in 80% of adults.
970:
911:
907:
867:
828:
808:
560:
382:
Around 30% of people have swollen, painful joints, but this is generally mild.
2571:
2491:
2487:
2067:
Cooper GS, Stroehla BC (May 2003). "The epidemiology of autoimmune diseases".
1946:
1403:
783:, along with polymyositis, necrotizing autoimmune myositis, cancer-associated
3135:
1900:
1669:
1013:
757:
689:
682:
678:
618:
610:
564:
262:
257:. Diagnosis is typically based on some combination of symptoms, blood tests,
139:
96:
2116:
540:
List of human leukocyte antigen alleles associated with cutaneous conditions
2966:
2843:
2694:
2398:
2181:
2124:
2088:
1954:
1919:
1814:
1779:
1715:
1688:
1637:
1563:
1513:
1469:
1411:
1337:
1302:
Papadopoulou C, Chew C, Wilkinson MG, McCann L, Wedderburn LR (June 2023).
1285:
1234:
1216:
1136:
963:
947:
891:
887:
846:
816:
812:
715:
697:
693:
629:
622:
390:
291:
287:
195:
191:
151:
70:
2244:
2216:
2053:
1555:
3090:
2710:
2552:
1867:. National Institute of Neurological Disorders and Stroke. 27 July 2015.
980:
977:
in 1977, died at the age of 29 from heart failure caused by this disease.
854:
568:
386:
370:
People with DM experience progressively worsening muscle weakness in the
159:
2961:
1622:"Cancer risk in dermatomyositis: a systematic review of the literature"
1009:
836:
820:
640:
614:
556:
545:
239:
182:
92:
2470:
1884:"Idiopathic Inflammatory Myopathies: Clinical Approach and Management"
1505:
602:
2938:
2820:
2563:
1021:
1012:; clinical trials were ongoing for use of the following drugs in DM:
860:
279:
234:
174:
950:(1923–1977) allegedly had dermatomyositis from 1975 until her death.
3024:
2675:
2580:
1266:
1198:
857:, are used to treat the rashes, as is done for similar conditions.
794:
A form of this disorder that occurs prior to adulthood is known as
784:
735:
656:
579:
371:
331:
1701:
1620:
Di Rollo D, Abeni D, Tracanna M, Capo A, Amerio P (October 2014).
776:, a class of diseases that often involves autoimmune dysfunction.
594:
44:
983:(1948–2011) a doctor, comedian, author, and the president of the
879:
644:
583:
575:
339:
230:
57:
53:
1757:
1651:
Simon JP, Marie I, Jouen F, Boyer O, Martinet J (14 June 2016).
1008:
As of 2016, research was ongoing into causes for DM, as well as
940:
2482:
1301:
918:
disease persists after adequate control of the muscle disease.
819:, may reduce inflammation in people who do not respond well to
394:
685:; and sharp activity when a needle is inserted into the muscle
468:
Gottron's papules in a severe case of juvenile dermatomyositis
2384:
753:
2101:
1115:
Callen JP, Wortmann RL (September 2006). "Dermatomyositis".
586:
seem to create a disposition to autoimmune dermatomyositis.
432:
Gottron's papules on the elbows of a person with juvenile DM
2495:
1491:
1201:"A Study on Dermatomyositis and the Relation to Malignancy"
703:
338:, which is red or violet, sometimes scaly, slightly raised
311:
226:
957:(1907–1989) had dermatomyositis from 1974 until his death.
1619:
2622:
863:
is used when people do not respond to other treatments.
1792:
1730:"ICD-10 Systemic connective tissue disorders (M30-M36)"
1247:
27:
Long-term inflammatory disorder of the skin and muscles
2145:
282:, and assistive devices, and rest. Medications in the
2427:
United States
Department of Health and Human Services
2313:. Pro Football Weekly. 8 January 2010. Archived from
1882:
Malik A, Hayat G, Kalia JS, Guzman MA (20 May 2016).
1881:
245:
The cause is unknown. Theories include that it is an
2460:
2444:
1932:
1650:
1447:
358:, and are often very itchy, painful, and may bleed.
286:
family are typically used with other agents such as
1994:
Genetic and Rare
Diseases Information Center (GARD)
1487:
1485:
1483:
1481:
1479:
606:
X-Ray of the knee in a person with dermatomyositis.
559:response. The most commonly associated cancers are
516:Severe rash on the hands, extending up the forearm
1753:
1751:
756:may be used to investigate joint involvement and
636:Muscle weakness in both thighs or both upper arms
3133:
2146:Bendewald MJ, Wetter DA, Li X, Davis MD (2010).
1859:
1857:
1626:Giornale Italiano di Dermatologia e Venereologia
1476:
310:The main symptoms include several kinds of skin
1593:
1591:
1589:
1587:
1585:
1583:
1581:
1174:NORD (National Organization for Rare Disorders)
330:" (a purplish color) or lilac, but may also be
2285:"Laurence Olivier Dies: 'The Rest Is Silence'"
2066:
1748:
1114:
294:recommended if steroids are not working well.
2859:
2608:
1854:
1443:
1441:
1439:
1437:
1435:
1433:
1431:
1429:
1248:Tansley SL, McHugh NJ, Wedderburn LR (2013).
941:People who were affected with dermatomyositis
779:It has also been classified as an idiopathic
2873:
1969:
1786:
1578:
456:Gottron's bumps on a person with juvenile DM
342:that erupt on any of the finger joints (the
1653:"Autoimmune Myopathies: Where Do We Stand?"
914:, and other drugs, the prognosis was poor.
574:Some cases are inherited, and HLA subtypes
551:Between 7 and 30% of dermatomyositis cases
3157:Steroid-responsive inflammatory conditions
2866:
2852:
2615:
2601:
2222:
2194:
1426:
1164:
1162:
1160:
1158:
1156:
1154:
1152:
1150:
1148:
1146:
1077:
1075:
1073:
1071:
1069:
1067:
1065:
1063:
1061:
43:
2171:
2039:
1909:
1899:
1678:
1668:
1615:
1613:
1327:
1275:
1265:
1224:
1110:
1108:
1059:
1057:
1055:
1053:
1051:
1049:
1047:
1045:
1043:
1041:
82:Rash, muscle weakness, weight loss, fever
1597:
973:in 1976, and the number-one pick in the
609:
601:
593:
480:Heliotrope with swelling around the eyes
1537:
1143:
14:
3134:
3066:Acrokeratosis paraneoplastica of Bazex
2947:Paraneoplastic cerebellar degeneration
2831:Congenital contractural arachnodactyly
2422:NINDS Dermatomyositis Information Page
1610:
1602:. Merck Manuals Professional Edition.
1389:
1105:
1038:
772:Dermatomyositis is a form of systemic
2847:
2596:
2335:
1979:, Blackwell Scientific. Third Edition
1871:from the original on 2 December 2016.
1606:from the original on 12 October 2015.
1533:
1531:
1180:from the original on 19 February 2017
305:
3162:Systemic connective tissue disorders
2929:Nonbacterial thrombotic endocarditis
1841:The Lecturio Medical Concept Library
1736:from the original on 8 February 2017
1385:
1383:
326:One form the rashes take is called "
2348:from the original on 1 October 2013
2265:from the original on 4 January 2015
993:, Indian actress diagnosed in 2022.
969:(1955–1984), the runner-up for the
714:Dermatomyositis is associated with
240:calcium deposits in muscles or skin
24:
2924:Multicentric reticulohistiocytosis
2291:from the original on 10 March 2011
1528:
1494:The British Journal of Dermatology
1129:10.1016/j.clindermatol.2006.07.001
598:Calcification from dermatomyositis
420:Gottron's papules on finger joints
356:made worse by exposure to sunlight
25:
3178:
2977:Lambert–Eaton myasthenic syndrome
2440:
2287:. People Magazine. 24 July 1989.
2261:. GR Reporter. 28 December 2010.
1380:
767:
2447:
2414: This article incorporates
2409:
2105:Annals of the Rheumatic Diseases
1975:Page 285 in: Thomson and Cotton
1254:Arthritis Research & Therapy
1093:from the original on 5 July 2017
730:), including antibodies against
521:
509:
497:
485:
473:
461:
449:
437:
425:
413:
399:hole somewhere in their GI tract
134:Based on symptoms, blood tests,
3107:Febrile neutrophilic dermatosis
3076:Florid cutaneous papillomatosis
2982:Anti-NMDA receptor encephalitis
2748:Mixed connective tissue disease
2378:
2360:
2329:
2303:
2277:
2251:
2225:New England Journal of Medicine
2197:New England Journal of Medicine
2188:
2139:
2095:
2060:
2033:
2007:
1982:
1926:
1875:
1829:
1722:
1695:
1644:
1544:New England Journal of Medicine
1205:Current Health Sciences Journal
924:
692:under a microscope and finding
233:. Its symptoms are generally a
205:~ 1 per 100,000 people per year
2724:Progressive systemic sclerosis
1540:"Inflammatory Muscle Diseases"
1354:"History of Dermatomyositis".
1347:
1295:
1241:
1192:
985:Humanist Association of Canada
318:in both upper arms or thighs.
13:
1:
3038:Necrolytic migratory erythema
2811:Eosinophilia–myalgia syndrome
2164:10.1001/archdermatol.2009.328
2081:10.1016/s1568-9972(03)00006-5
1865:"Dermatomyositis Information"
1807:10.1016/S0140-6736(08)60955-1
1031:
694:mononuclear white blood cells
3071:Extramammary Paget's disease
2640:Systemic lupus erythematosus
1772:10.1016/j.autrev.2016.01.015
1538:Dalakas MC (30 April 2015).
1462:10.1016/j.autrev.2016.07.013
1392:Current Rheumatology Reports
1024:(Phase IV, open label), and
999:(2005–2024), Indian actress.
901:
823:. Periodic treatment using
801:
589:
7:
2625:connective tissue disorders
2336:Jones T (12 October 2011).
2237:10.1056/nejm197502202920807
2209:10.1056/nejm197502132920706
2042:The Journal of Rheumatology
1935:Seminars in Immunopathology
1364:10.1007/978-3-540-79313-7_2
1308:Nature Reviews Rheumatology
1018:adrenocorticotropic hormone
1003:
740:signal recognition particle
643:, finding higher levels of
409:Examples of dermatomyositis
395:black tarry bowel movements
10:
3183:
3147:Connective tissue diseases
2901:Zollinger–Ellison syndrome
1977:Lecture Notes in Pathology
1320:10.1038/s41584-023-00967-9
932:
884:intravenous immunoglobulin
825:intravenous immunoglobulin
774:connective tissue disorder
750:Magnetic resonance imaging
728:anti-synthetase antibodies
724:aminoacyl-tRNA synthetases
537:
365:
344:metacarpophalangeal joints
296:Intravenous immunoglobulin
278:, exercise, heat therapy,
173:, exercise, heat therapy,
3099:
3046:
3022:
3013:
2990:
2937:
2914:
2881:
2783:
2760:
2739:
2709:
2666:
2653:Libman–Sacks endocarditis
2638:
2631:
2543:
2464:
1947:10.1007/s00281-015-0543-z
1598:Hajj-ali RA (June 2013).
1404:10.1007/s11926-010-0100-7
533:
201:
181:
177:, assistive devices, rest
165:
145:
128:
120:
110:
102:
86:
76:
64:
51:
42:
37:
3117:Paraneoplastic pemphigus
2875:Paraneoplastic syndromes
2690:Juvenile dermatomyositis
1901:10.3389/fneur.2016.00064
1670:10.3389/fimmu.2016.00234
849:medications, especially
796:juvenile dermatomyositis
377:
3033:Erythema gyratum repens
3005:Hypertrophic osteopathy
2699:Inclusion body myositis
2311:"Forgotten: Ricky Bell"
2152:Archives of Dermatology
2117:10.1136/ard.2008.093161
1657:Frontiers in Immunology
789:inclusion body myositis
321:
156:inclusion body myositis
2816:Ehlers–Danlos syndrome
2806:Eosinophilic fasciitis
2801:Polymyalgia rheumatica
2416:public domain material
2338:"Rob Buckman obituary"
2019:Johns Hopkins Medicine
1888:Frontiers in Neurology
1837:"Dermatomyositis (DM)"
1358:. 2009. pp. 5–8.
1217:10.12865/CHSJ.47.03.07
1117:Clinics in Dermatology
876:calcineurin inhibitors
720:antinuclear antibodies
665:pyruvate transaminases
661:glutamate oxaloacetate
625:
607:
599:
348:interphalangeal joints
147:Differential diagnosis
2668:Inflammatory myopathy
1556:10.1056/NEJMra1402225
896:mycophenolate mofetil
878:applied to the skin,
870:, taken or orally or
781:inflammatory myopathy
732:histidine—tRNA ligase
669:lactate dehydrogenase
613:
605:
597:
255:inflammatory myopathy
223:inflammatory disorder
95:, lung inflammation,
3112:Pyoderma gangrenosum
3061:Ichthyosis acquisita
3056:Acanthosis nigricans
2791:IgG4-related disease
2719:Systemic scleroderma
2069:Autoimmunity Reviews
1760:Autoimmunity Reviews
1450:Autoimmunity Reviews
744:anti-Mi-2 antibodies
617:of dermatomyositis,
3167:Idiopathic diseases
3152:Disorders of fascia
3142:Autoimmune diseases
2972:Transverse myelitis
2957:Limbic encephalitis
2681:Dermatopolymyositis
2374:. 18 February 2024.
1801:(9631): 2201–2212.
872:applied to the skin
681:that have multiple
397:, or may develop a
3086:Pityriasis rotunda
2906:Cushing's syndrome
2544:External resources
2372:The Times of India
2317:on 11 January 2010
2021:. 19 November 2019
1026:sodium thiosulfate
851:hydroxychloroquine
626:
608:
600:
306:Signs and symptoms
247:autoimmune disease
225:which affects the
3129:
3128:
3125:
3124:
3081:Leser-Trélat sign
2952:Encephalomyelitis
2841:
2840:
2756:
2755:
2590:
2589:
2015:"Dermatomyositis"
1990:"Dermatomyositis"
1550:(18): 1734–1747.
1506:10.1111/bjd.14726
1373:978-3-540-79312-0
1170:"Dermatomyositis"
1083:"Dermatomyositis"
961:American football
738:); antibodies to
555:, probably as an
553:arise from cancer
444:Gottron's papules
352:Gottron's papules
249:or a result of a
209:
208:
130:Diagnostic method
32:Medical condition
16:(Redirected from
3174:
3020:
3019:
2868:
2861:
2854:
2845:
2844:
2796:Behçet's disease
2775:Sjögren syndrome
2763:hypersensitivity
2744:Overlap syndrome
2648:Drug-induced SLE
2636:
2635:
2617:
2610:
2603:
2594:
2593:
2462:
2461:
2457:
2452:
2451:
2450:
2437:
2435:
2433:
2413:
2412:
2403:
2402:
2382:
2376:
2375:
2364:
2358:
2357:
2355:
2353:
2333:
2327:
2326:
2324:
2322:
2307:
2301:
2300:
2298:
2296:
2281:
2275:
2274:
2272:
2270:
2255:
2249:
2248:
2220:
2192:
2186:
2185:
2175:
2143:
2137:
2136:
2111:(7): 1192–1196.
2099:
2093:
2092:
2064:
2058:
2057:
2048:(6): 1140–1148.
2037:
2031:
2030:
2028:
2026:
2011:
2005:
2004:
2002:
2000:
1986:
1980:
1973:
1967:
1966:
1930:
1924:
1923:
1913:
1903:
1879:
1873:
1872:
1861:
1852:
1851:
1849:
1847:
1833:
1827:
1826:
1790:
1784:
1783:
1755:
1746:
1745:
1743:
1741:
1726:
1720:
1719:
1699:
1693:
1692:
1682:
1672:
1648:
1642:
1641:
1617:
1608:
1607:
1595:
1576:
1575:
1535:
1526:
1525:
1500:(6): 1248–1255.
1489:
1474:
1473:
1445:
1424:
1423:
1387:
1378:
1377:
1351:
1345:
1344:
1331:
1299:
1293:
1292:
1279:
1269:
1245:
1239:
1238:
1228:
1196:
1190:
1189:
1187:
1185:
1166:
1141:
1140:
1112:
1103:
1102:
1100:
1098:
1079:
997:Suhani Bhatnagar
955:Laurence Olivier
833:cyclophosphamide
675:electromyography
525:
513:
501:
489:
477:
465:
453:
441:
429:
417:
276:physical therapy
259:electromyography
171:physical therapy
136:electromyography
47:
35:
34:
21:
3182:
3181:
3177:
3176:
3175:
3173:
3172:
3171:
3132:
3131:
3130:
3121:
3095:
3042:
3009:
3000:Dermatomyositis
2992:Musculoskeletal
2986:
2933:
2910:
2877:
2872:
2842:
2837:
2826:Marfan syndrome
2779:
2752:
2735:
2705:
2686:Dermatomyositis
2662:
2658:Lupus nephritis
2627:
2621:
2591:
2586:
2585:
2539:
2538:
2473:
2455:Medicine portal
2453:
2448:
2446:
2443:
2431:
2429:
2419:
2410:
2407:
2406:
2383:
2379:
2366:
2365:
2361:
2351:
2349:
2334:
2330:
2320:
2318:
2309:
2308:
2304:
2294:
2292:
2283:
2282:
2278:
2268:
2266:
2257:
2256:
2252:
2193:
2189:
2144:
2140:
2100:
2096:
2065:
2061:
2038:
2034:
2024:
2022:
2013:
2012:
2008:
1998:
1996:
1988:
1987:
1983:
1974:
1970:
1931:
1927:
1880:
1876:
1863:
1862:
1855:
1845:
1843:
1835:
1834:
1830:
1791:
1787:
1756:
1749:
1739:
1737:
1728:
1727:
1723:
1700:
1696:
1649:
1645:
1618:
1611:
1596:
1579:
1536:
1529:
1490:
1477:
1446:
1427:
1388:
1381:
1374:
1356:Dermatomyositis
1353:
1352:
1348:
1300:
1296:
1246:
1242:
1197:
1193:
1183:
1181:
1168:
1167:
1144:
1113:
1106:
1096:
1094:
1081:
1080:
1039:
1034:
1006:
943:
935:
927:
904:
804:
787:, and sporadic
770:
653:creatine kinase
649:skeletal muscle
592:
542:
536:
529:
526:
517:
514:
505:
502:
493:
490:
481:
478:
469:
466:
457:
454:
445:
442:
433:
430:
421:
418:
380:
368:
324:
316:muscle weakness
308:
284:corticosteroids
263:muscle biopsies
251:viral infection
212:Dermatomyositis
188:Corticosteroids
140:muscle biopsies
38:Dermatomyositis
33:
28:
23:
22:
15:
12:
11:
5:
3180:
3170:
3169:
3164:
3159:
3154:
3149:
3144:
3127:
3126:
3123:
3122:
3120:
3119:
3114:
3109:
3103:
3101:
3097:
3096:
3094:
3093:
3088:
3083:
3078:
3073:
3068:
3063:
3058:
3052:
3050:
3048:Papulosquamous
3044:
3043:
3041:
3040:
3035:
3029:
3027:
3017:
3011:
3010:
3008:
3007:
3002:
2996:
2994:
2988:
2987:
2985:
2984:
2979:
2974:
2969:
2964:
2959:
2954:
2949:
2943:
2941:
2935:
2934:
2932:
2931:
2926:
2920:
2918:
2912:
2911:
2909:
2908:
2903:
2898:
2893:
2891:Hypercalcaemia
2887:
2885:
2879:
2878:
2871:
2870:
2863:
2856:
2848:
2839:
2838:
2836:
2835:
2834:
2833:
2828:
2818:
2813:
2808:
2803:
2798:
2793:
2787:
2785:
2781:
2780:
2778:
2777:
2771:
2769:
2758:
2757:
2754:
2753:
2751:
2750:
2740:
2737:
2736:
2734:
2733:
2732:
2731:
2729:CREST syndrome
2726:
2715:
2713:
2707:
2706:
2704:
2703:
2702:
2701:
2692:
2678:
2672:
2670:
2664:
2663:
2661:
2660:
2655:
2650:
2644:
2642:
2633:
2629:
2628:
2620:
2619:
2612:
2605:
2597:
2588:
2587:
2584:
2583:
2574:
2560:
2548:
2547:
2545:
2541:
2540:
2537:
2536:
2525:
2514:
2499:
2474:
2469:
2468:
2466:
2465:Classification
2459:
2458:
2442:
2441:External links
2439:
2405:
2404:
2393:(4): 273–279.
2377:
2359:
2328:
2302:
2276:
2250:
2231:(8): 403–407.
2203:(7): 344–347.
2187:
2138:
2094:
2075:(3): 119–125.
2059:
2032:
2006:
1981:
1968:
1925:
1874:
1853:
1828:
1785:
1747:
1721:
1710:(5): 354–358.
1694:
1643:
1632:(5): 525–537.
1609:
1577:
1527:
1475:
1456:(10): 948–54.
1425:
1398:(3): 192–197.
1379:
1372:
1346:
1314:(6): 343–362.
1294:
1267:10.1186/ar4198
1240:
1211:(3): 377–382.
1191:
1142:
1123:(5): 363–373.
1104:
1036:
1035:
1033:
1030:
1005:
1002:
1001:
1000:
994:
988:
978:
971:Heisman Trophy
958:
951:
942:
939:
934:
931:
926:
923:
912:chemotherapies
908:plasmapheresis
903:
900:
829:cyclosporine A
809:corticosteroid
803:
800:
769:
768:Classification
766:
758:calcifications
716:autoantibodies
708:
707:
701:
686:
671:
637:
591:
588:
561:ovarian cancer
535:
532:
531:
530:
527:
520:
518:
515:
508:
506:
503:
496:
494:
491:
484:
482:
479:
472:
470:
467:
460:
458:
455:
448:
446:
443:
436:
434:
431:
424:
422:
419:
412:
410:
379:
376:
367:
364:
336:Gottron's sign
323:
320:
307:
304:
207:
206:
203:
199:
198:
185:
179:
178:
167:
163:
162:
149:
143:
142:
132:
126:
125:
122:
118:
117:
112:
108:
107:
104:
100:
99:
90:
84:
83:
80:
74:
73:
68:
62:
61:
56:overlying the
49:
48:
40:
39:
31:
26:
9:
6:
4:
3:
2:
3179:
3168:
3165:
3163:
3160:
3158:
3155:
3153:
3150:
3148:
3145:
3143:
3140:
3139:
3137:
3118:
3115:
3113:
3110:
3108:
3105:
3104:
3102:
3098:
3092:
3089:
3087:
3084:
3082:
3079:
3077:
3074:
3072:
3069:
3067:
3064:
3062:
3059:
3057:
3054:
3053:
3051:
3049:
3045:
3039:
3036:
3034:
3031:
3030:
3028:
3026:
3021:
3018:
3016:
3015:Mucocutaneous
3012:
3006:
3003:
3001:
2998:
2997:
2995:
2993:
2989:
2983:
2980:
2978:
2975:
2973:
2970:
2968:
2965:
2963:
2960:
2958:
2955:
2953:
2950:
2948:
2945:
2944:
2942:
2940:
2936:
2930:
2927:
2925:
2922:
2921:
2919:
2917:
2916:Hematological
2913:
2907:
2904:
2902:
2899:
2897:
2894:
2892:
2889:
2888:
2886:
2884:
2880:
2876:
2869:
2864:
2862:
2857:
2855:
2850:
2849:
2846:
2832:
2829:
2827:
2824:
2823:
2822:
2819:
2817:
2814:
2812:
2809:
2807:
2804:
2802:
2799:
2797:
2794:
2792:
2789:
2788:
2786:
2782:
2776:
2773:
2772:
2770:
2768:
2764:
2759:
2749:
2745:
2742:
2741:
2738:
2730:
2727:
2725:
2722:
2721:
2720:
2717:
2716:
2714:
2712:
2708:
2700:
2696:
2693:
2691:
2687:
2684:
2683:
2682:
2679:
2677:
2674:
2673:
2671:
2669:
2665:
2659:
2656:
2654:
2651:
2649:
2646:
2645:
2643:
2641:
2637:
2634:
2630:
2626:
2618:
2613:
2611:
2606:
2604:
2599:
2598:
2595:
2582:
2578:
2575:
2573:
2570:
2566:
2565:
2561:
2559:
2555:
2554:
2550:
2549:
2546:
2542:
2535:
2531:
2530:
2526:
2524:
2520:
2519:
2515:
2513:
2509:
2508:
2504:
2500:
2497:
2493:
2489:
2485:
2484:
2480:
2476:
2475:
2472:
2467:
2463:
2456:
2445:
2438:
2428:
2424:
2423:
2417:
2400:
2396:
2392:
2388:
2381:
2373:
2369:
2363:
2347:
2343:
2339:
2332:
2316:
2312:
2306:
2290:
2286:
2280:
2264:
2260:
2254:
2246:
2242:
2238:
2234:
2230:
2226:
2218:
2214:
2210:
2206:
2202:
2198:
2191:
2183:
2179:
2174:
2169:
2165:
2161:
2157:
2153:
2149:
2142:
2134:
2130:
2126:
2122:
2118:
2114:
2110:
2106:
2098:
2090:
2086:
2082:
2078:
2074:
2070:
2063:
2055:
2051:
2047:
2043:
2036:
2020:
2016:
2010:
1995:
1991:
1985:
1978:
1972:
1964:
1960:
1956:
1952:
1948:
1944:
1941:(1): 113–21.
1940:
1936:
1929:
1921:
1917:
1912:
1907:
1902:
1897:
1893:
1889:
1885:
1878:
1870:
1866:
1860:
1858:
1842:
1838:
1832:
1824:
1820:
1816:
1812:
1808:
1804:
1800:
1796:
1789:
1781:
1777:
1773:
1769:
1765:
1761:
1754:
1752:
1735:
1731:
1725:
1717:
1713:
1709:
1705:
1698:
1690:
1686:
1681:
1676:
1671:
1666:
1662:
1658:
1654:
1647:
1639:
1635:
1631:
1627:
1623:
1616:
1614:
1605:
1601:
1594:
1592:
1590:
1588:
1586:
1584:
1582:
1573:
1569:
1565:
1561:
1557:
1553:
1549:
1545:
1541:
1534:
1532:
1523:
1519:
1515:
1511:
1507:
1503:
1499:
1495:
1488:
1486:
1484:
1482:
1480:
1471:
1467:
1463:
1459:
1455:
1451:
1444:
1442:
1440:
1438:
1436:
1434:
1432:
1430:
1421:
1417:
1413:
1409:
1405:
1401:
1397:
1393:
1386:
1384:
1375:
1369:
1365:
1361:
1357:
1350:
1343:
1339:
1335:
1330:
1325:
1321:
1317:
1313:
1309:
1305:
1298:
1291:
1287:
1283:
1278:
1273:
1268:
1263:
1259:
1255:
1251:
1244:
1236:
1232:
1227:
1222:
1218:
1214:
1210:
1206:
1202:
1195:
1179:
1175:
1171:
1165:
1163:
1161:
1159:
1157:
1155:
1153:
1151:
1149:
1147:
1138:
1134:
1130:
1126:
1122:
1118:
1111:
1109:
1092:
1088:
1084:
1078:
1076:
1074:
1072:
1070:
1068:
1066:
1064:
1062:
1060:
1058:
1056:
1054:
1052:
1050:
1048:
1046:
1044:
1042:
1037:
1029:
1027:
1023:
1019:
1015:
1014:ajulemic acid
1011:
998:
995:
992:
989:
986:
982:
979:
976:
972:
968:
965:
962:
959:
956:
952:
949:
946:Opera singer
945:
944:
938:
930:
922:
919:
915:
913:
909:
899:
897:
893:
889:
885:
881:
877:
873:
869:
864:
862:
858:
856:
852:
848:
844:
840:
838:
834:
830:
826:
822:
818:
814:
810:
799:
797:
792:
790:
786:
782:
777:
775:
765:
761:
759:
755:
751:
747:
745:
741:
737:
733:
729:
725:
721:
718:, especially
717:
712:
705:
702:
699:
695:
691:
690:muscle biopsy
687:
684:
680:
679:motor neurons
676:
672:
670:
666:
662:
658:
654:
650:
646:
642:
638:
635:
634:
633:
631:
624:
623:H&E stain
620:
619:muscle biopsy
616:
612:
604:
596:
587:
585:
581:
577:
572:
570:
566:
565:breast cancer
562:
558:
554:
549:
547:
541:
524:
519:
512:
507:
500:
495:
488:
483:
476:
471:
464:
459:
452:
447:
440:
435:
428:
423:
416:
411:
408:
407:
406:
402:
400:
396:
392:
388:
383:
375:
373:
363:
359:
357:
353:
349:
345:
341:
337:
333:
329:
319:
317:
313:
303:
299:
297:
293:
289:
285:
281:
277:
272:
269:
266:
264:
260:
256:
252:
248:
243:
241:
236:
232:
228:
224:
221:
217:
213:
204:
200:
197:
193:
189:
186:
184:
180:
176:
172:
168:
164:
161:
157:
153:
150:
148:
144:
141:
137:
133:
131:
127:
123:
119:
116:
113:
109:
105:
101:
98:
97:heart disease
94:
91:
89:
88:Complications
85:
81:
79:
75:
72:
69:
67:
63:
59:
55:
52:Discrete red
50:
46:
41:
36:
30:
19:
2999:
2967:Polymyositis
2939:Neurological
2695:Polymyositis
2685:
2576:
2562:
2551:
2527:
2516:
2501:
2477:
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2342:The Guardian
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1086:
1028:(Phase II).
1016:(Phase II),
1007:
964:running back
948:Maria Callas
936:
928:
925:Epidemiology
920:
916:
905:
892:azathioprine
888:methotrexate
865:
859:
847:Antimalarial
845:
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817:methotrexate
813:azathioprine
805:
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748:
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709:
698:phagocytosis
688:Examining a
651:, including
630:polymyositis
627:
573:
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543:
528:Forearm rash
403:
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292:azathioprine
288:methotrexate
273:
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196:azathioprine
192:methotrexate
169:Medication,
152:Polymyositis
71:Rheumatology
29:
3091:Tripe palms
2711:Scleroderma
2553:MedlinePlus
2432:12 December
981:Rob Buckman
855:chloroquine
742:(SRP); and
569:lung cancer
504:Facial rash
391:vomit blood
387:arrhythmias
314:along with
160:scleroderma
103:Usual onset
3136:Categories
2962:Opsoclonus
2767:autoimmune
2529:DiseasesDB
2321:26 January
1740:9 December
1260:(2): 211.
1032:References
1010:biomarkers
967:Ricky Bell
837:tacrolimus
821:prednisone
641:blood test
615:Micrograph
557:autoimmune
548:response.
546:autoimmune
538:See also:
492:Heliotrope
328:heliotrope
183:Medication
106:40s to 50s
93:Calcinosis
18:Shawl sign
3023:Reactive
2883:Endocrine
2821:fibrillin
2623:Systemic
2564:eMedicine
2269:1 January
1823:205951454
1022:abatacept
975:NFL draft
902:Prognosis
861:Rituximab
802:Treatment
647:found in
590:Diagnosis
280:orthotics
235:skin rash
220:long-term
202:Frequency
175:orthotics
166:Treatment
115:Long term
66:Specialty
3025:erythema
2676:Myositis
2569:med/2608
2498:M33.910)
2399:27784516
2346:Archived
2289:Archived
2263:Archived
2182:20083689
2133:21500536
2125:18713785
2089:12848952
1955:26563285
1920:27242652
1869:Archived
1815:18586175
1780:26826433
1734:Archived
1716:27871347
1689:27379096
1638:24975953
1604:Archived
1572:37761391
1564:25923553
1522:45638288
1514:27167896
1470:27481041
1420:29083422
1412:20425525
1338:37188756
1329:10184643
1286:23566358
1235:35003769
1178:Archived
1176:. 2015.
1137:16966018
1091:Archived
1089:. 2017.
1004:Research
991:Samantha
868:steroids
785:myositis
736:Anti-Jo1
657:aldolase
639:Using a
580:HLA-DR52
372:proximal
229:and the
111:Duration
78:Symptoms
58:knuckles
2632:General
2581:Q681160
2577:Scholia
2572:derm/98
2523:D003882
2387:Skinmed
2352:16 July
2295:16 July
2245:1089199
2217:1090839
2173:2886726
2054:4093921
2025:11 July
1999:11 July
1963:7104535
1911:4873503
1846:11 July
1732:. WHO.
1704:Skinmed
1680:4905946
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1277:3672700
1226:8679146
1184:13 July
1097:13 July
933:History
880:dapsone
645:enzymes
584:HLA-DR6
576:HLA-DR3
393:, have
366:Muscles
346:or the
340:papules
231:muscles
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567:, and
534:Causes
261:, and
121:Causes
3100:Other
2896:SIADH
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2492:M33.1
2488:M33.0
2418:from
2129:S2CID
1959:S2CID
1819:S2CID
1568:S2CID
1518:S2CID
1416:S2CID
754:X-ray
378:Other
54:areas
2518:MeSH
2507:9-CM
2496:ILDS
2434:2016
2395:PMID
2354:2012
2323:2010
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2121:PMID
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2050:PMID
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1466:PMID
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1368:ISBN
1334:PMID
1282:PMID
1231:PMID
1186:2017
1133:PMID
1099:2017
1087:GARD
853:and
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667:and
322:Skin
312:rash
227:skin
2503:ICD
2479:ICD
2233:doi
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