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Sodium thiopental

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1180:, the sole American manufacturer of the drug, objected to the use of thiopental in lethal injection. "Hospira manufactures this product because it improves or saves lives, and the company markets it solely for use as indicated on the product labeling. The drug is not indicated for capital punishment and Hospira does not support its use in this procedure." On January 21, 2011, the company announced that it would stop production of sodium thiopental from its plant in Italy, because it could not provide Italian authorities with guarantees that exported doses would not be used in executions. According to a company spokesperson, Italy was the only viable place where it could produce the drug, leaving the US without a supplier. 746: 58: 583: 560: 49: 12120: 898:(gas) agent. Inhaled anesthetics are eliminated relatively quickly, so that stopping the inhaled anesthetic will allow rapid return of consciousness. Sodium thiopental would have to be given in large amounts to maintain unconsciousness during anaesthesia due to its rapid redistribution throughout the body (as it has a high 1037:. A very large dose is given to ensure rapid loss of consciousness. Although death usually occurs within ten minutes of the beginning of the injection process, some have been known to take longer. The use of sodium thiopental in execution protocols was challenged in court after a study in the medical journal 1088:
to weaken the resolve of a subject and make the individual more compliant to pressure. Barbiturates decrease both higher cortical brain function and inhibition. It is thought that because lying is a more involved process than telling the truth, suppression of the higher cortical functions may lead to
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in the US, the United Kingdom introduced a ban on the export of sodium thiopental in December 2010, after it was established that no European supplies to the US were being used for any other purpose. The restrictions were based on "the European Union Torture Regulation (including licensing of drugs
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Intravenous administration is the most reliable and rapid way to accomplish euthanasia. Death is quick. A coma is first induced by intravenous administration of 20 mg/kg thiopental sodium (Nesdonal) in a small volume (10 mL physiological saline). Then, a triple dose of a non-depolarizing
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in reducing intracranial pressure. This phenomenon is also called an inverse steal or Robin Hood effect as cerebral perfusion to all parts of the brain is reduced (due to the decreased cerebrovascular response to carbon dioxide) allowing optimal perfusion to ischaemic areas of the brain which have
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used in execution by lethal injection)". From 21 December 2011, the EU extended trade restrictions to prevent the export of certain medicinal products for capital punishment, stating that "the Union disapproves of capital punishment in all circumstances and works towards its universal abolition".
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receptor currents are increased by barbiturates (and other general anesthetics), ligand-gated ion channels that are predominantly permeable for cationic ions are blocked by these compounds. For example, neuronal nAChR are blocked by clinically relevant anesthetic concentrations of both sodium
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will have prolonged recoveries from sodium thiopental due to their lack of body fat and their lean body mass. Conversely, obese animals will have rapid recoveries, but it will take much longer for the drug to be entirely removed (metabolized) from their bodies. Sodium thiopental is always
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confiscated an overseas shipment of thiopental destined for the states of Arizona and Texas. FDA spokesman Jeff Ventura said in a statement, "Courts have concluded that sodium thiopental for the injection in humans is an unapproved drug and may not be imported into the country".
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within 30–45 seconds. At one minute, the drug attains a peak concentration of about 60% of the total dose in the brain. Thereafter, the drug distributes to the rest of the body, and in about 5–10 minutes the concentration is low enough in the brain that consciousness returns.
1395:. It was first used in human beings on March 8, 1934, by Dr. Ralph M. Waters in an investigation of its properties, which were short-term anesthesia and surprisingly little analgesia. Three months later, Dr. John S. Lundy started a clinical trial of thiopental at the 1241:, as do specific disease states and other patient factors. Among patient factors are: age, sex, and lean body mass. Specific disease conditions that can alter the dose requirements of thiopentone and for that matter any other intravenous anaesthetic are: 10030: 1204:
molecule. As with all lipid-soluble anaesthetic drugs, the short duration of action of sodium thiopental is due almost entirely to its redistribution away from central circulation into muscle and fatty tissue, due to its very high lipid–water
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On December 8, 2009, Ohio became the first state to use a single dose of sodium thiopental for an execution, following the failed use of the standard three-drug cocktail during a prior execution, due to inability to locate suitable veins.
950:, either secondary to trauma or following surgery, may benefit from this drug. Sodium thiopental, and the barbiturate class of drugs, decrease neuronal activity thereby decreasing cerebral metabolic rate of oxygen consumption (CMRO 9651: 8392: 1305:. Intravenous administration of sodium thiopental is followed instantly by an odor and/or taste sensation, sometimes described as being similar to rotting onions, or to garlic. Residual side-effects may last up to 36 hours. 9970: 8380: 1606:
The selection and use of essential medicines : report of the WHO Expert Committee, March 2011 (including the 17th WHO model list of essential medicines and the 3rd WHO model list of essential medicines for
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Abraham P, Rennert RC, Gabel BC, Sack JA, Karanjia N, Warnke P, Chen CC (December 2017). "ICP management in patients suffering from traumatic brain injury: a systematic review of randomized controlled trials".
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obstruction. For these reasons, thiopental should only be administered by suitably trained medical personnel, who should give thiopental in an environment equipped to provide (respiratory) support, such as
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was the first in the state to use a single-dose, single-drug injection. His death was pronounced approximately one and a half minutes after the intravenous administration of five grams of the drug.
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of executed inmates showed the level of thiopental in their bloodstream was insufficient to cause unconsciousness although this is dependent on different factors and not just on the drug itself.
7385: 803:. Despite this, thiopental is listed as an acceptable alternative to propofol, depending on local availability and cost of these agents. It was the first of three drugs administered during most 6335: 1729:
Bryson EO (December 2014). "The Abuse of Agents Used to Induce or Maintain General Anesthesia: Intravenous Hypnotics and the Halogenated Hydrocarbons". In Kaye AD, Vadivelu N, Urman RD (eds.).
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the uncovering of the truth. The drug tends to make subjects verbose and cooperative with interrogators; however, the reliability of confessions made under thiopental is questionable.
8961: 3032: 211: 991:. In both Belgium and the Netherlands, where active euthanasia is allowed by law, the standard protocol recommends sodium thiopental as the ideal agent to induce coma, followed by 1410:. These deaths, relatively soon after the drug's introduction, were said to be due to excessive doses given to shocked trauma patients. However, recent evidence available through 8981: 954:), decrease the cerebrovascular response to carbon dioxide, which in turn decreases intracranial pressure. Patients with refractory elevated intracranial pressure (RICH) due to 9015: 8384: 6447: 5136: 2590: 8554: 11655: 9751: 7832: 1707: 12091: 11005: 9897: 1465: 1225:
The usual dose range for induction of anesthesia using thiopental is from 3 to 6 mg/kg; however, there are many factors that can alter this. Premedication with
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Washington State became the second state in the US to use the single-dose sodium thiopental injections for executions. On September 10, 2010, the execution of
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Russo H, Brès J, Duboin MP, Roquefeuil B (1995). "Pharmacokinetics of thiopental after single and multiple intravenous doses in critical care patients".
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higher metabolic demands, since vessels supplying ischaemic areas of the brain would already be maximally dilated because of the metabolic demand.
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banned the export of the drug for this purpose. Although thiopental abuse carries a dependency risk, its recreational use is rare.
2617:"Metabolism of thiopental-S35 and thiopental-2-C14 by a rat liver mince and identification of pentobarbital as a major metabolite" 942:. It has now been superseded by drugs such as propofol because their effects wear off more quickly than thiopental. Patients with 11795: 9287: 8738: 1217:, 5-ethyl-5-(1'-methyl-3'-hydroxybutyl)-2-thiobarbituric acid, and 5-ethyl-5-(1'-methyl-3'-carboxypropyl)-2-thiobarbituric acid. 10180: 10015: 9429: 9262: 9197: 1164:
receptor is an inhibitory channel that decreases neuronal activity, and barbiturates enhance the inhibitory action of the GABA
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at the request of Abbott. Abbott continued to make the drug until 2004, when it spun off its hospital-products division as
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InChI=1S/C11H18N2O2S.Na/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);/q;+1/p-1
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Sodium thiopental is not used to maintain anesthesia in surgical procedures because, in infusion, it displays
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A normal dose of sodium thiopental (usually 4–6 mg/kg) given to a pregnant woman for operative delivery (
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and to "facilitate the recall of painful repressed memories." One psychiatrist who worked with thiopental is
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is added to their neurointensive care treatment. Reportedly, thiopental has been shown to be superior to
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Franks NP, Lieb WR (November 1998). "Which molecular targets are most relevant to general anaesthesia?".
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but pancuronium bromide may be administered intramuscularly at an increased dosage level of 40 mg.
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Pereda J, Gómez-Cambronero L, Alberola A, Fabregat G, Cerdá M, Escobar J, et al. (October 2006).
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Pearlman T (December 1980). "Behavioral desensitization of phobic anxiety using thiopental sodium".
12055: 9685: 7146: 7142: 6315: 4734: 4548: 3181: 2813:"Co-administration of pentoxifylline and thiopental causes death by acute pulmonary oedema in rats" 1176:
Following a shortage that led a court to delay an execution in California, a company spokesman for
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class of drugs, which are relatively non-selective compounds that bind to an entire superfamily of
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channel is one of several representatives. This superfamily of ion channels includes the neuronal
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Shibata Y, Yokooji T, Itamura R, Sagara Y, Taogoshi T, Ogawa K, et al. (December 2016).
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remains conscious. However, larger or repeated doses can depress the baby's consciousness.
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Bory C, Chantin C, Boulieu R, Cotte J, Berthier JC, Fraisse D, Bobenrieth MJ (1986). "".
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Thiopental is famously associated with a number of anesthetic deaths in victims of the
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In addition to anesthesia induction, sodium thiopental was historically used to induce
844: 780: 106: 2488: 2162:"Kenneth Biros Execution: Ohio Man First to Die Under 1-Drug Thiopental Sodium Method" 12060: 11780: 11660: 10794: 9700: 9414: 8982: 8323: 8203: 7704: 7475: 7418: 7359: 7127: 6699: 5794: 5571: 5114: 4247: 4205: 4038: 3713: 3256: 3161: 3001: 2951: 2918: 2842: 2793: 2696: 2691: 2674: 2655: 2628: 2492: 2461: 2365: 2324: 2187: 2058: 2001: 1934: 1876: 1851: 1752: 1742: 1630: 1620: 1555: 1550: 1533: 1503: 930:
and sloughing can occur if it is injected incorrectly into the tissue around a vein.
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of 5.5 to 26 hours is quite long, consciousness would take a long time to return.
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drug is given, such as 20 mg pancuronium bromide (Pavulon) or 20 mg
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administered intravenously, as it can be fairly irritating to tissue and is a
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World Health Organization model list of essential medicines: 22nd list (2021)
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World Health Organization model list of essential medicines: 21st list 2019
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Substance abuse: inpatient and outpatient management for every clinician
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Newsletter of the Multidisciplinary Association for Psychedelic Studies
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Tooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
8856: 8813: 8798: 8793: 8664: 8608: 8604: 8497: 8428: 8368: 8308: 8303: 8269: 8179: 8175: 8116: 8106: 8085: 8031: 7935: 7902: 7657: 7609: 7604: 7589: 7547: 7542: 7500: 7495: 7490: 7448: 7344: 7329: 7269: 7254: 7239: 7059: 6970: 6925: 6890: 6880: 6850: 6845: 6830: 6804: 6766: 6761: 6738: 6733: 6718: 6624: 6619: 6500: 6378: 6368: 6360: 6295: 6272: 6252: 6247: 6217: 6202: 6172: 6154: 6144: 6139: 6134: 6129: 6109: 6094: 6089: 6079: 6074: 6069: 6039: 6014: 5964: 5949: 5944: 5929: 5914: 5894: 5889: 5879: 5869: 5864: 5859: 5779: 5774: 5749: 5679: 5659: 5629: 5551: 5486: 5416: 5406: 5371: 5268: 5172: 5078: 4872: 4762: 4729: 4664: 4576: 4541: 4493: 4336: 4289: 4096: 4081: 4071: 4061: 3970: 3932: 3922: 3914: 3899: 3856: 3846: 3841: 3811: 3766: 3703: 3638: 3425: 3312: 3284: 3274: 3246: 3131: 3126: 3116: 2430:
Weber M, Motin L, Gaul S, Beker F, Fink RH, Adams DJ (January 2005).
2114: 1820:Çakırtekin V, Yıldırım A, Bakan N, Çelebi N, Bozkurt Ö (April 2015). 1527: 1525: 1353: 1234: 1157: 1106: 394: 92: 1033:, thiopental is used in 34 states of the US to execute prisoners by 362:
sodium 5-ethyl-5-pentan-2-yl-2-sulfanylidene-1,3-diazinane-4,6-dione
48: 12019: 11945: 11760: 11750: 11570: 11325: 11315: 11275: 11270: 11260: 11225: 11175: 11170: 11075: 10889: 10687: 10594: 10419: 10404: 10319: 10234: 10150: 10040: 9922: 9853: 9843: 9705: 9571: 9469: 9277: 8851: 8637: 8622: 8612: 8600: 8469: 8459: 8445: 8259: 8125: 8101: 8060: 7925: 7714: 7647: 7624: 7573: 7569: 7565: 7505: 7479: 7339: 7299: 7279: 7259: 7249: 7189: 7184: 6998: 6960: 6910: 6875: 6840: 6835: 6819: 6814: 6794: 6789: 6784: 6771: 6659: 6467: 6344: 6330: 6305: 6300: 6290: 6262: 6049: 6044: 6024: 6004: 5999: 5799: 5754: 5734: 5699: 5689: 5576: 5531: 5521: 5426: 5321: 5301: 5217: 5099: 5062: 5053: 4947: 4699: 4428: 4398: 4324: 4259: 4114: 4091: 4086: 4051: 3904: 3836: 3698: 3613: 3517: 3513: 3371: 3327: 3307: 3279: 3208: 3198: 3121: 2241: 2210: 2166: 1337: 1309: 1246: 1226: 923: 848: 800: 488: 419: 1522: 1320:, and does not show the allergic reactions of sulfa/sulpha drugs. 657: 12015: 11995: 11575: 11546: 11400: 11395: 11390: 11385: 11375: 11279: 11165: 11100: 11095: 10933: 10779: 10769: 10749: 10704: 10190: 9805: 9790: 9756: 9690: 9581: 9459: 9177: 9107: 9087: 9035: 8748: 8580: 8249: 8195: 8133: 8036: 7940: 7886: 7878: 7863: 7842: 7837: 7661: 7651: 7410: 7349: 7324: 7319: 7194: 7174: 7154: 6975: 6965: 6950: 6935: 6920: 6905: 6900: 6885: 6870: 6751: 6490: 6350: 5804: 5511: 5212: 5007: 4744: 4558: 4433: 4329: 4236: 3955: 3688: 3190: 1400: 1177: 1044: 808: 2472: 1097:
Psychiatrists have used thiopental to desensitize patients with
11605: 11425: 11235: 11020: 10809: 10709: 10082: 9813: 9795: 9772: 9067: 9062: 8576: 7894: 7850: 7594: 7557: 7179: 7132: 7003: 6985: 6945: 6629: 6427: 5058: 4210: 4106: 3299: 2890:(9). American Society of Anesthesiologists: 7–9. Archived from 1313: 1302: 1285: 1098: 880: 519: 2880:"The Investigator and His 'Uncompromising Scientific Honesty'" 11975: 10804: 10229: 10020: 9746: 9556: 9082: 9072: 8209: 6955: 5083: 4403: 3171: 2911:
The Journal of the American Association of Nurse Anesthetists
2722: 2614: 1819: 1281: 811:
objected and stopped manufacturing the drug in 2011, and the
648: 499: 293: 8969: 2615:
Winters WD, Spector E, Wallach DP, Shideman FE (July 1955).
2109:
Royal Dutch Society for the Advancement of Pharmacy (1994).
987:
Sodium thiopental is used intravenously for the purposes of
544: 10697: 10524: 10110: 10097: 9731: 9551: 9521: 9511: 9424: 9257: 9222: 9212: 9010: 8669: 8541: 8214: 6388: 3550: 2947:
History of Anesthesia with Emphasis on the Nurse Specialist
2388: 1902: 1578:
WHO Model List of Essential Medicines 16th list, March 2009
1156:
thiopental and pentobarbital. Such findings implicate (non-
851:, but may retain some popularity as an induction agent for 826:," although its efficacy in this role has been questioned. 479: 11033: 9935: 8155: 2917:(2). American Association of Nurse Anesthetists: 95–102. 2621:
The Journal of Pharmacology and Experimental Therapeutics
2541:"US executions delayed by shortage of death penalty drug" 1678: 1647: 1600: 1572: 1485: 2423: 2263:"Controls on torture goods - Detailed guidance - GOV.UK" 1665:. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO. 2645: 2234:"US lethal injection drug faces UK export restrictions" 1982: 1532:
Morgan DJ, Blackman GL, Paull JD, Wolf LJ (June 1981).
1531: 1387:
Sodium thiopental was discovered in the early 1930s by
797:
World Health Organization's List of Essential Medicines
11456: 11052: 10227:
Uncompetitive pore blockers (mostly dizocilpine site):
5144: 822:, especially under the name "sodium pentothal," as a " 12108: 9633: 8680: 4923: 2417:
Multidisciplinary Association for Psychedelic Studies
2203:"Drug sold in UK to be used for execution in Georgia" 2111:"Administration and Compounding of Euthanasic Agents" 879:) rapidly makes her unconscious, but the baby in her 843:
and has been used commonly in the induction phase of
3041:. Vol. 35, issue 4. June 18, 2008. pp. 957–968. 2672: 2648:
Comptes Rendus de l'Académie des Sciences, Série III
2566:"Key death penalty drug discontinued by U.S. maker" 2429: 2140:"Ohio executes inmate with 1-drug lethal injection" 1328:Thiopental should be used with caution in cases of 1826:Turkish Journal of Anaesthesiology and Reanimation 1580:. Geneva, Switzerland: World Health Organization. 1367:in rats. This pulmonary edema was not mediated by 776:(also a trademark), is a rapid-onset short-acting 7697:Unsorted benzodiazepine site positive modulators: 979:, thiopental may be used to terminate a seizure. 847:. Its use has been largely replaced with that of 12132: 2863:. Anesthesia History Association. Archived from 2747:. eMedicineHealth. 12 April 2009. Archived from 2078:"Anesthetic Management of Head-injured Patients" 867:, the drug rapidly reaches the brain and causes 407: 7777: 2294: 2029:"Barbiturates for acute traumatic brain injury" 2026: 1862: 958:(TBI) may have improved long term outcome when 795:. Sodium thiopental was a core medicine in the 379: 11951:Trimetaphan camsilate (trimethaphan camsylate) 9885: 9870: 3512: 3074: 2405:"The LSD Therapy Career of Jan Bastiaans, M.D" 2183:"Killer on death row 16-1/2 years is executed" 2104: 2102: 807:in the United States until the US division of 12206:World Health Organization essential medicines 12151:GABAA receptor positive allosteric modulators 12092:Acetylcholine metabolism/transport modulators 11006: 8955: 8839: 8726: 7763: 5130: 4527:Serotonin antagonists and reuptake inhibitors 3498: 3060: 2563: 2318: 1954:"TRAUMA.ORG: Critical Care: Barbiturate Coma" 1213:. Sodium thiopental is mainly metabolized to 1084:Thiopental is still used in some places as a 12087:Muscarinic acetylcholine receptor modulators 2302:"Truth serum used on 'serial child killers'" 2020: 1976: 5146: 4916: 2971: 2099: 2033:The Cochrane Database of Systematic Reviews 1868: 1055:was executed using the single-drug method. 839:Sodium thiopental is an ultra-short-acting 11013: 10999: 10972:Metabotropic glutamate receptor modulators 8962: 8948: 7770: 7756: 5137: 5123: 3505: 3491: 3067: 3053: 2538: 2478: 1196:Thiopental rapidly and easily crosses the 581: 558: 447: 139:Intravenous (most common), oral, or rectal 11038:Tooltip Nicotinic acetylcholine receptors 10979:Glutamate metabolism/transport modulators 2995: 2980:"Thiopentone anaesthesia at Pearl Harbor" 2877: 2861:"This Month in Anesthesia History: March" 2836: 2787: 2769: 2690: 2515:University of Virginia School of Medicine 2455: 2288:"EU Council Regulation (EU) No 1352/2011" 2052: 1928: 1875:. Elsevier Health Sciences. p. 169. 1845: 1691: 1674: 1672: 1660: 1614: 1585: 1549: 1488:European Journal of Clinical Pharmacology 933: 467: 11581:Candocuronium iodide (chandonium iodide) 9391: 8928:Ionotropic glutamate receptor modulators 7807: 2977: 2939: 2402: 2343: 2231: 2180: 2159: 995:to paralyze muscles and stop breathing. 744: 2673:Avram M, Krejcie T, Henthorn T (1990). 2588: 2321:The Howdunit Book of Poisons (Howdunit) 2027:Roberts I, Sydenham E (December 2012). 1293:. Other side-effects include headache, 1272:, thiopental causes cardiovascular and 554: 427: 12133: 11461:Tooltip negative allosteric modulators 11057:Tooltip positive allosteric modulators 10702:Alcohols/volatile anesthetics/related: 1869:Gleason CA, Juul SE (12 August 2011). 1728: 1669: 1641: 1452: 1112: 913:, sodium thiopental is used to induce 572: 242: 10994: 9858:Other positive allosteric modulators: 9638:Tooltip N-Methyl-D-aspartate receptor 8943: 8685:Tooltip N-Methyl-D-aspartate receptor 7751: 5118: 5103: 3486: 3048: 3023:PubChem Substance Summary: Thiopental 2904: 1771:"Can a drug make you tell the truth?" 1686:. Geneva: World Health Organization. 1655:. Geneva: World Health Organization. 1609:. Geneva: World Health Organization. 1363:and thiopental causes death by acute 1123:Sodium thiopental is a member of the 970: 527: 507: 254: 97: 8377:4-hydroxyquinoline-3-carboxylic acid 8235:4-Phenyl-4-formyl-N-methylpiperidine 7738:GABA metabolism/transport modulators 5104: 2564:Welsh-Huggins A (January 21, 2011). 2323:. Cincinnati: Writers Digest Books. 2132: 1323: 1151:and others. Surprisingly, while GABA 178: 168: 83:Truth serum, thiopentone, thiopental 10599:Ifenprodil (NR2B) site antagonists: 8200:trichloroethane (methyl chloroform) 7355:Trichloroethane (methyl chloroform) 2075: 1909:Biochemistry and Biophysics Reports 1733:. New York: Springer. p. 115. 1637:. WHO technical report series; 965. 1391:and Donalee L. Tabern, working for 1375:but was due to increased pulmonary 1014: 818:Sodium thiopental is well-known in 487: 398: 13: 9163:Pesampator (BIIB-104, PF-04958242) 8804:Pesampator (BIIB-104, PF-04958242) 6418:11-Methoxy-12-hydroxydehydrokavain 2346:The American Journal of Psychiatry 1951: 1412:freedom of information legislation 14: 12217: 11666:Dimethyltubocurarine (metocurine) 7165:Acetylglycinamide chloral hydrate 4232:Acetylglycinamide chloral hydrate 3016: 2142:. Associated Press. December 2001 1794: 1185:U.S. Food and Drug Administration 205: 117: 12118: 11022:Nicotinic acetylcholine receptor 2692:10.1097/00000542-199003000-00002 2354:American Psychiatric Association 2181:Sullivan J (10 September 2010). 1551:10.1097/00000542-198106000-00006 1237:will reduce requirements due to 1171: 1141:nicotinic acetylcholine receptor 612: 606: 56: 47: 12046:Meclofenoxate (centrophenoxine) 11371:Suxethonium (succinyldicholine) 11366:Suxamethonium (succinylcholine) 10639:Rislenemdaz (CERC-301, MK-0657) 9586:Negative allosteric modulators: 9474:Positive allosteric modulators: 9297:Negative allosteric modulators: 9050:Positive allosteric modulators: 7585:Menthyl isovalerate (validolum) 2933: 2898: 2878:Steinhaus JE (September 2001). 2871: 2853: 2817:British Journal of Pharmacology 2804: 2770:James MF, Hift RJ (July 2000). 2763: 2737: 2707: 2666: 2639: 2608: 2582: 2557: 2532: 2503: 2436:British Journal of Pharmacology 2396: 2376: 2337: 2312: 2280: 2255: 2232:Casciani D (29 November 2010). 2225: 2195: 2174: 2153: 2069: 1945: 1896: 1872:Avery's Diseases of the Newborn 1813: 1788: 1763: 1468:from the original on 2023-08-03 1260: 717:Key:AWLILQARPMWUHA-UHFFFAOYSA-M 692:.O=C1NC(=S)/N=C(/)C1(C(C)CCC)CC 9875:Tooltip Dehydroepiandrosterone 9183:Tulrampator (S-47445, CX-1632) 9078:Farampator (CX-691, ORG-24448) 6534:Allopregnanolone (brexanolone) 3029:Thiopental in Lethal Injection 2984:British Journal of Anaesthesia 2978:Bennetts FE (September 1995). 2942:"Chapter 7: Illegal or Legal?" 2776:British Journal of Anaesthesia 2589:Solomon D (October 27, 2015). 2160:Martinez E (8 December 2009). 2045:10.1002/14651858.CD000033.pub2 1722: 1710:. Spiegel Online International 1700: 1594: 1566: 1479: 1446: 1417:British Journal of Anaesthesia 1073: 1067:execution of Jeffrey Landrigan 627: 621: 618: 600: 231: 218: 16:Barbiturate general anesthetic 1: 12082:Receptor/signaling modulators 11736:Hexamethonium (benzohexonium) 10965:Receptor/signaling modulators 10814:Unknown/unsorted antagonists: 9378:Unknown/unsorted antagonists: 8971:Ionotropic glutamate receptor 8903:Receptor/signaling modulators 8844:Tooltip Glycine transporter 2 8754:Bitopertin (RG1678/RO4917838) 8731:Tooltip Glycine transporter 1 7730:Receptor/signaling modulators 6286:Ampelopsin (dihydromyricetin) 2489:10.1016/S0378-4274(98)00158-1 2319:Bannon A, Stevens SD (2007). 1439: 1191: 1092: 982: 834: 12171:Kainate receptor antagonists 8921:receptor positive modulators 7480:ergoloid (dihydroergotoxine) 6565:anabolic-androgenic steroids 5347:Butabarbital/Secbutabarbital 5152:receptor positive modulators 2308:. Reuters. January 12, 2007. 1739:10.1007/978-1-4939-1951-2_10 783:. It is the thiobarbiturate 7: 12176:Lethal injection components 11816:Methorphan (racemethorphan) 11146:Bephenium hydroxynaphthoate 10663:NR2A-selective antagonists: 10195:Polyamine site antagonists: 9420:Acromelic acid (acromelate) 9006:Acromelic acid (acromelate) 6120:Triflunordazepam (Ro5-2904) 4758:Tetracyclic antidepressants 4572:Tetracyclic antidepressants 2539:Pilkington E (2010-09-28). 1921:10.1016/j.bbrep.2016.09.005 1427: 1312:of thiopental contains one 10: 12222: 11196:Dimethylphenylpiperazinium 9103:Hydrochlorothiazide (HCTZ) 7959:chlorobutanol (chloretone) 6448:5,6,7,8-Tetrahydroyangonin 2511:"Anesthesia and Analgesia" 1696:. WHO/MHP/HPS/EML/2021.02. 1382: 1116: 1077: 1018: 590:Chemical and physical data 31: 20: 12191:Drugs developed by Pfizer 12161:Glycine receptor agonists 12146:AMPA receptor antagonists 12141:Drugs developed by AbbVie 12074: 11988: 11449: 11045: 11031: 10956: 10045:Glycine site antagonists: 9631: 9389: 8980: 8894: 8837: 8724: 8707: 8678: 8074:pregnenolone (eltanolone) 8051:Glutamic acid (glutamate) 7805: 7788: 7723: 7373: 7141: 7078: 7045: 7012: 6984: 6698: 6640:Pregnanolone (eltanolone) 6519: 6476: 6387: 6359: 6271: 6153: 5595: 5282: 5183:Chlorobutanol (cloretone) 5158: 5112: 4961: 4914: 4886: 4853: 4833: 4779: 4735:Tricyclic antidepressants 4720: 4708: 4651: 4593: 4549:Tricyclic antidepressants 4517: 4454: 4442: 4371: 4219: 4156: 4123: 4105: 4037: 3984: 3941: 3913: 3855: 3732: 3589: 3541: 3529: 3443: 3418: 3390: 3357: 3298: 3265: 3217: 3189: 3180: 3087: 3038:Fordham Urban Law Journal 1998:10.1007/s00701-017-3363-1 1680:World Health Organization 1649:World Health Organization 1602:World Health Organization 1574:World Health Organization 1352:, or a family history of 1220: 1129:ligand-gated ion channels 749:Pentothal vintage package 725: 700: 680: 668: 646: 633: 594: 589: 570: 538: 518: 498: 478: 458: 438: 418: 393: 370: 350: 345: 335: 322: 312: 299: 287: 277: 269: 195: 190: 155: 143: 131: 105: 87: 79: 69: 64: 55: 46: 12056:Phosphatidylethanolamine 9933:Competitive antagonists: 9841:Polyamine site agonists: 9827:Neboglamine (nebostinel) 9396:Tooltip Kainate receptor 8910:GABA receptor modulators 7812:Tooltip Glycine receptor 7734:GABA receptor modulators 7644:sulfonmethane (sulfonal) 4320:Sulfonmethane (sulfonal) 2745:"Pentothal (thiopental)" 1464:(published 2023-04-04). 853:rapid-sequence induction 799:, but was supplanted by 21:Not to be confused with 11836:Morphanol (racemorphan) 11776:Laudexium (laudolissin) 11186:Desformylflustrabromine 10915:Pentamidine isethionate 10659:Traxoprodil (CP-101606) 9898:Epipregnanolone sulfate 8555:3β-androsterone sulfate 8551:3α-androsterone sulfate 4807:Atypical antipsychotics 4621:Atypical antipsychotics 2905:Lundy JS (April 1966). 2362:10.1176/ajp.137.12.1580 1838:10.5152/TJAR.2014.75547 1462:Diário Oficial da União 946:, causing elevation of 829: 10945:Allosteric modulators: 10880:Ipenoxazone (MLV-6976) 10535:Pethidine (meperidine) 10156:Licostinel (ACEA-1021) 10078:Apimostinel (NRX-1074) 9742:Apimostinel (NRX-1074) 9710:Glycine site agonists: 9542:Licostinel (ACEA-1021) 9253:Licostinel (ACEA-1021) 9138:Mibampator (LY-451395) 8799:ORG-25935 (SCH-900435) 7988:Alkylbenzene sulfonate 7620:Retigabine (ezogabine) 6896:Lirequinil (Ro41-3696) 6463:7,8-Dihydromethysticin 6453:5,6-Dehydromethysticin 5332:Benzylbutylbarbiturate 4981:Chlorophenylalkyldiols 4789:Typical antipsychotics 4603:Typical antipsychotics 3027:Vassallo, Susi, M.D. " 2829:10.1038/sj.bjp.0706871 2483:. 100–101 (1–2): 1–8. 2448:10.1038/sj.bjp.0705942 1408:attack on Pearl Harbor 1373:pulmonary hypertension 1291:mechanical ventilation 1274:respiratory depression 1065:After its use for the 1001:neuromuscular blocking 956:traumatic brain injury 934:Medically-induced coma 900:volume of distribution 750: 12181:Nicotinic antagonists 12041:Glycerophosphocholine 10614:CO-101244 (PD-174494) 10330:Delucemine (NPS-1506) 10280:Alazocine (SKF-10047) 8872:Opiranserin (VVZ-149) 8172:diethyl ether (ether) 2306:Sydney Morning Herald 1422:Tripler Army Hospital 1377:vascular permeability 1359:Co-administration of 1207:partition coefficient 1078:Further information: 1019:Further information: 948:intracranial pressure 915:anesthesia in animals 865:intravenous injection 748: 12186:Organic sodium salts 12036:Dimethylethanolamine 11901:Rapacuronium bromide 11881:Pipecuronium bromide 11721:Gantacurium chloride 11681:Dizocilpine (MK-801) 11266:MEM-63,908 (RG-3487) 11216:Ethoxysebacylcholine 10634:Radiprodil (RGH-896) 10609:Buphenine (nylidrin) 10186:Rapastinel (GLYX-13) 10001:Midafotel (d-CPPene) 9908:Pregnenolone sulfate 9832:Rapastinel (GLYX-13) 9623:Pregnenolone sulfate 9364:Pregnenolone sulfate 8567:pregnenolone sulfate 8547:Neuroactive steroids 8505:constituents (e.g., 8465:Cyanotriphenylborate 8426:Negative modulators: 8349:N,N-Dimethylmuscimol 8275:Cyanotriphenylborate 8112:Tetrahydrocannabinol 8078:pregnenolone acetate 8066:Neuroactive steroids 8039:constituents (e.g., 7948:Positive modulators: 7675:constituents (e.g., 7459:Deuterated etifoxine 6521:Neuroactive steroids 6491:Apronal (apronalide) 6343:constituents (e.g., 5960:N-Desalkylflurazepam 4938:Gabapentin enacarbil 3986:Neuroactive steroids 3956:Apronal (apronalide) 3392:Neuroactive steroids 3359:Arylcyclohexylamines 2997:10.1093/bja/75.3.366 2940:Thatcher VS (1953). 2789:10.1093/bja/85.1.143 2392:. February 24, 1958. 2082:www.amcresidents.com 1986:Acta Neurochirurgica 1414:was reviewed in the 1183:In October 2015 the 227:(Psychoactive drugs) 34:Sound of White Noise 12156:General anesthetics 12051:Phosphatidylcholine 11936:Threohydrobupropion 11921:Stercuronium iodide 11856:Pancuronium bromide 9865:-Hydroxycholesterol 9676:Homoquinolinic acid 9649:Main site agonists: 9407:Main site agonists: 9001:5-Fluorowillardiine 8998:Main site agonists: 8559:deoxycorticosterone 8339:N-Methylbicuculline 7468:dihydroergocryptine 6780:Pyrazolopyrimidines 6438:5,6-Dihydroyangonin 6423:7,8-Dihydroyangonin 5610:3-Hydroxyphenazepam 5452:Methylphenobarbital 3076:General anesthetics 2950:. J.B. Lippincott. 2403:Snelders S (1998). 1393:Abbott Laboratories 1265:As with nearly all 1211:zero-order kinetics 1198:blood–brain barrier 1113:Mechanism of action 1027:pancuronium bromide 993:pancuronium bromide 911:veterinary medicine 791:, and an analog of 762:Abbott Laboratories 386:76-75-5 (free acid) 214:(Prescription only) 75:Pentothal, Trapanal 43: 11971:Vecuronium bromide 11911:Rocuronium bromide 11821:Methyllycaconitine 11746:Hydroxynorketamine 11641:Dextropropoxyphene 11626:Dehydronorketamine 11616:Dacuronium bromide 10213:Diethylenetriamine 9892:prasterone sulfate 9667:Homocysteic acid ( 9410:5-Bromowillardiine 8769:Glycyldodecylamide 8373:4-hydroxyquinoline 8344:N-Methylstrychnine 7562:4-O-methylhonokiol 7225:Dichloralphenazone 7123:Methylmethaqualone 6700:Nonbenzodiazepines 6413:Desmethoxyyangonin 6408:11-Hydroxyyangonin 6403:11-Methoxyyangonin 6398:10-Methoxyyangonin 5785:Ethyl carfluzepate 5387:Cyclopentobarbital 5003:Diethylpropanediol 4285:Dichloralphenazone 4201:Methylmethaqualone 4039:Nonbenzodiazepines 3566:Diethylpropanediol 3470:Never to phase III 2751:on 18 January 2015 2725:. 15 November 2021 2481:Toxicology Letters 1500:10.1007/BF00192371 1389:Ernest H. Volwiler 1350:breathing disorder 1316:atom, it is not a 1295:agitated emergence 1031:potassium chloride 1005:vecuronium bromide 977:status epilepticus 971:Status epilepticus 896:inhaled anesthetic 845:general anesthesia 781:general anesthetic 751: 337:Duration of action 39: 12106: 12105: 12100: 12099: 12061:Phosphorylcholine 11999: 11984: 11983: 11781:Levacetylmethadol 11661:Dihydrochandonium 11541:sodium thiopental 11211:Ethanol (alcohol) 10988: 10987: 10839: 10795:Trichloroethylene 10740:Ethanol (alcohol) 10105: 10048:4-Cl-KYN (AV-101) 9816: 9808: 9775: 9767: 9759: 9716: 9701:Tetrazolylglycine 9670: 9608:Ethanol (alcohol) 9597:sodium thiopental 9415:5-Iodowillardiine 9324:Ethanol (alcohol) 9308:sodium thiopental 8937: 8936: 8890: 8889: 8862:Ethanol (alcohol) 8764:Ethanol (alcohol) 8718: 8703: 8702: 8324:Isonipecotic acid 8230:2-Nitrostrychnine 8225:2-Aminostrychnine 8204:trichloroethylene 8006:sodium thiopental 7963:ethanol (alcohol) 7905: 7897: 7889: 7881: 7853: 7845: 7799: 7745: 7744: 7705:MRK-409 (MK-0343) 7476:dihydroergotamine 7419:potassium bromide 7413:compounds (e.g., 7360:Trichloroethylene 7128:Nitromethaqualone 7047:Pyrazolopyridines 6549:3α-Androstanediol 6443:7,8-Dihydrokavain 5795:Ethyl loflazepate 5572:Thiotetrabarbital 5188:Ethanol (alcohol) 5097: 5096: 4849: 4848: 4647: 4646: 4367: 4366: 4248:Potassium bromide 4206:Nitromethaqualone 3714:Thiotetrabarbital 3561:Ethanol (alcohol) 3480: 3479: 3439: 3438: 3257:Thiotetrabarbital 3162:Trichloroethylene 2384:"Drugged Future?" 2330:978-1-58297-456-9 2213:. 24 January 2011 2188:The Seattle Times 1992:(12): 2279–2287. 1964:on 19 August 2016 1334:Addison's disease 1324:Contraindications 877:caesarean section 805:lethal injections 754:Sodium thiopental 743: 742: 659:Interactive image 540:CompTox Dashboard 258: 246: 234: 222: 209: 121: 41:Sodium thiopental 12213: 12201:Thiobarbiturates 12123: 12122: 12121: 12114: 11993: 11931:Thiocolchicoside 11741:Hydroxybupropion 11636:Dextromethorphan 11508:Allopregnanolone 11462: 11458: 11361:Suberyldicholine 11071:6-Chloronicotine 11058: 11054: 11043: 11042: 11039: 11035: 11015: 11008: 11001: 10992: 10991: 10837: 10790:Trichloroethanol 10350:Dextromethorphan 10103: 9887: 9876: 9872: 9814: 9806: 9773: 9765: 9757: 9714: 9668: 9639: 9635: 9397: 9393: 9228:Fanapanel (MPQX) 8988: 8984: 8964: 8957: 8950: 8941: 8940: 8845: 8841: 8732: 8728: 8722: 8721: 8712: 8686: 8682: 8585:dextromethorphan 8475:Dihydropyridines 8414:Thiocolchicoside 8364:Pseudostrychnine 8304:Gaboxadol (THIP) 8298:anandamide (AEA) 8290:Endocannabinoids 8022:Dihydropyridines 7982:trifluoroethanol 7978:trichloroethanol 7903: 7895: 7887: 7879: 7851: 7843: 7813: 7809: 7803: 7802: 7793: 7779:Glycine receptor 7772: 7765: 7758: 7749: 7748: 7464:Dihydroergolines 7381:3-Hydroxybutanal 7014:Piperidinediones 6747:Imidazopyridines 6281:6-Methylapigenin 6213:Hydroxyphenamate 6085:SH-053-R-CH3-2′F 5790:Ethyl dirazepate 5670:Chlordiazepoxide 5562:Thiobutabarbital 5274:Trifluoroethanol 5264:Trichloroethanol 5254:-Pentanol (2M2B) 5148: 5139: 5132: 5125: 5116: 5115: 5106:Pharmacodynamics 5101: 5100: 5022:muscle relaxants 4925: 4922: 4718: 4717: 4452: 4451: 4389:4-Fluorophenibut 4125:Piperidinediones 3999:Allopregnanolone 3581:Trichloroethanol 3539: 3538: 3507: 3500: 3493: 3484: 3483: 3187: 3186: 3069: 3062: 3055: 3046: 3045: 3010: 3009: 2999: 2975: 2969: 2968: 2966: 2960:. Archived from 2937: 2931: 2930: 2925:. Archived from 2902: 2896: 2895: 2875: 2869: 2868: 2857: 2851: 2850: 2840: 2808: 2802: 2801: 2791: 2767: 2761: 2760: 2758: 2756: 2741: 2735: 2734: 2732: 2730: 2711: 2705: 2704: 2694: 2670: 2664: 2663: 2643: 2637: 2636: 2612: 2606: 2605: 2603: 2601: 2586: 2580: 2579: 2577: 2576: 2561: 2555: 2554: 2552: 2551: 2536: 2530: 2529: 2527: 2526: 2517:. Archived from 2507: 2501: 2500: 2476: 2470: 2469: 2459: 2427: 2421: 2420: 2400: 2394: 2393: 2380: 2374: 2373: 2341: 2335: 2334: 2316: 2310: 2309: 2298: 2292: 2291: 2284: 2278: 2277: 2275: 2273: 2259: 2253: 2252: 2250: 2248: 2229: 2223: 2222: 2220: 2218: 2199: 2193: 2192: 2178: 2172: 2171: 2157: 2151: 2150: 2148: 2147: 2136: 2130: 2129: 2127: 2126: 2117:. Archived from 2106: 2097: 2096: 2094: 2093: 2084:. Archived from 2073: 2067: 2066: 2056: 2039:(12): CD000033. 2024: 2018: 2017: 1980: 1974: 1973: 1971: 1969: 1960:. Archived from 1949: 1943: 1942: 1932: 1900: 1894: 1893: 1891: 1889: 1866: 1860: 1859: 1849: 1817: 1811: 1810: 1808: 1807: 1801:Business Insider 1792: 1786: 1785: 1783: 1782: 1767: 1761: 1760: 1726: 1720: 1719: 1717: 1715: 1704: 1698: 1697: 1695: 1676: 1667: 1666: 1664: 1645: 1639: 1638: 1618: 1598: 1592: 1591: 1589: 1570: 1564: 1563: 1553: 1529: 1520: 1519: 1483: 1477: 1476: 1474: 1473: 1450: 1149:glycine receptor 1060:Cal Coburn Brown 1035:lethal injection 1021:Lethal injection 1015:Lethal injection 960:barbiturate coma 892:pharmacokinetics 760:(a trademark of 758:Sodium Pentothal 756:, also known as 739: 738: 731: 661: 641: 629: 623: 620: 614: 608: 602: 585: 574: 563: 562: 548: 546: 531: 511: 491: 471: 451: 431: 411: 401: 400: 383: 327: 256: 253: 244: 241: 233: 230: 220: 217: 207: 204: 182: 172: 119: 116: 101: 60: 51: 44: 42: 38: 12221: 12220: 12216: 12215: 12214: 12212: 12211: 12210: 12131: 12130: 12129: 12119: 12117: 12109: 12107: 12102: 12101: 12096: 12070: 11992: 11980: 11586:Chlorisondamine 11460: 11453: 11445: 11056: 11049: 11037: 11027: 11019: 10989: 10984: 10952: 10850:Flufenamic acid 10785:Trichloroethane 10560:Rhynchophylline 10480:Methoxphenidine 10445:Levomilnacipran 10345:Dextromethadone 10270:α-Endopsychosin 9874: 9786:Dimethylglycine 9696:Quinolinic acid 9637: 9627: 9465:Quisqualic acid 9395: 9385: 9041:Quisqualic acid 8986: 8976: 8968: 8938: 8933: 8920: 8886: 8843: 8833: 8744:ALX-5407 (NFPS) 8730: 8711: 8699: 8684: 8674: 8434:Benzodiazepines 8319:Isobutyric acid 8160:chloral hydrate 8012:Chlormethiazole 7974:tribromoethanol 7970:-butanol (2M2P) 7811: 7792: 7784: 7776: 7746: 7741: 7719: 7677:isovaleric acid 7640:Sulfonylalkanes 7538:Hopantenic acid 7522:tolfenamic acid 7510:flufenamic acid 7472:dihydroergosine 7415:lithium bromide 7374:Others/unsorted 7369: 7230:Dichloromethane 7205:Chloral hydrate 7200:Chloral betaine 7137: 7074: 7041: 7008: 6980: 6709:Cyclopyrrolones 6694: 6600:Etiocholanolone 6515: 6472: 6433:5-Hydroxykavain 6383: 6355: 6267: 6149: 5597:Benzodiazepines 5591: 5402:Ethallobarbital 5397:Enallylpropymal 5278: 5259:Tribromoethanol 5246:-Butanol (2M2P) 5192:alcoholic drink 5154: 5151: 5143: 5108: 5098: 5093: 4957: 4920: 4910: 4882: 4845: 4829: 4775: 4722:Antidepressants 4713: 4704: 4675:Dexmedetomidine 4656: 4643: 4589: 4519:Antidepressants 4513: 4474:Diphenhydramine 4447: 4438: 4376: 4363: 4352:Isovaleric acid 4315:Sulfonylalkanes 4270:Chloral hydrate 4265:Chloral betaine 4243:Lithium bromide 4215: 4152: 4119: 4101: 4033: 3980: 3937: 3909: 3851: 3734:Benzodiazepines 3728: 3634:Ethallobarbital 3585: 3534: 3525: 3511: 3481: 3476: 3475: 3460:Clinical trials 3435: 3414: 3386: 3353: 3294: 3267:Benzodiazepines 3261: 3213: 3176: 3083: 3073: 3019: 3014: 3013: 2976: 2972: 2964: 2958: 2938: 2934: 2903: 2899: 2876: 2872: 2859: 2858: 2854: 2809: 2805: 2768: 2764: 2754: 2752: 2743: 2742: 2738: 2728: 2726: 2713: 2712: 2708: 2671: 2667: 2644: 2640: 2613: 2609: 2599: 2597: 2587: 2583: 2574: 2572: 2562: 2558: 2549: 2547: 2537: 2533: 2524: 2522: 2509: 2508: 2504: 2477: 2473: 2428: 2424: 2401: 2397: 2382: 2381: 2377: 2342: 2338: 2331: 2317: 2313: 2300: 2299: 2295: 2286: 2285: 2281: 2271: 2269: 2261: 2260: 2256: 2246: 2244: 2230: 2226: 2216: 2214: 2201: 2200: 2196: 2179: 2175: 2158: 2154: 2145: 2143: 2138: 2137: 2133: 2124: 2122: 2107: 2100: 2091: 2089: 2074: 2070: 2025: 2021: 1981: 1977: 1967: 1965: 1950: 1946: 1901: 1897: 1887: 1885: 1883: 1867: 1863: 1818: 1814: 1805: 1803: 1793: 1789: 1780: 1778: 1769: 1768: 1764: 1749: 1727: 1723: 1713: 1711: 1706: 1705: 1701: 1677: 1670: 1646: 1642: 1627: 1599: 1595: 1571: 1567: 1530: 1523: 1494:(1–2): 127–37. 1484: 1480: 1471: 1469: 1451: 1447: 1442: 1430: 1385: 1369:cardiac failure 1365:pulmonary edema 1326: 1263: 1255:hypoproteinemia 1231:benzodiazepines 1223: 1194: 1174: 1167: 1163: 1154: 1136: 1131:, of which the 1121: 1115: 1095: 1082: 1076: 1023: 1017: 1009:bioavailability 985: 973: 953: 936: 928:tissue necrosis 869:unconsciousness 837: 832: 820:popular culture 734: 732: 729:(what is this?) 726: 721: 718: 713: 708: 707: 696: 693: 688: 687: 675:Racemic mixture 664: 639: 626: 617: 611: 605: 566: 542: 534: 514: 494: 474: 454: 434: 414: 397: 389: 385: 366: 363: 358: 357: 325: 314:Onset of action 279:Protein binding 271:Pharmacokinetic 265: 186: 134: 127: 108: 37: 30: 17: 12: 11: 5: 12219: 12209: 12208: 12203: 12198: 12193: 12188: 12183: 12178: 12173: 12168: 12163: 12158: 12153: 12148: 12143: 12128: 12127: 12104: 12103: 12098: 12097: 12095: 12094: 12089: 12084: 12079: 12075: 12072: 12071: 12069: 12068: 12063: 12058: 12053: 12048: 12043: 12038: 12033: 12028: 12023: 12013: 12008: 12002: 12000: 11986: 11985: 11982: 11981: 11979: 11978: 11973: 11968: 11963: 11958: 11953: 11948: 11943: 11938: 11933: 11928: 11923: 11918: 11913: 11908: 11903: 11898: 11893: 11888: 11883: 11878: 11873: 11868: 11863: 11858: 11853: 11848: 11843: 11838: 11833: 11828: 11823: 11818: 11813: 11808: 11803: 11798: 11793: 11788: 11783: 11778: 11773: 11768: 11766:Kynurenic acid 11763: 11758: 11753: 11748: 11743: 11738: 11733: 11728: 11723: 11718: 11713: 11708: 11703: 11698: 11693: 11688: 11683: 11678: 11673: 11668: 11663: 11658: 11653: 11648: 11643: 11638: 11633: 11628: 11623: 11618: 11613: 11608: 11603: 11598: 11593: 11588: 11583: 11578: 11573: 11568: 11563: 11560:κ-bungarotoxin 11556:α-bungarotoxin 11549: 11544: 11530: 11525: 11520: 11515: 11510: 11505: 11500: 11495: 11494:, many others) 11484:α-bungarotoxin 11477: 11472: 11466: 11464: 11447: 11446: 11444: 11443: 11438: 11433: 11428: 11423: 11418: 11416:Tribendimidine 11413: 11408: 11403: 11398: 11393: 11388: 11383: 11378: 11373: 11368: 11363: 11358: 11353: 11348: 11343: 11341:Sebacylcholine 11338: 11333: 11328: 11323: 11318: 11313: 11308: 11303: 11298: 11293: 11288: 11283: 11273: 11268: 11263: 11258: 11253: 11248: 11243: 11238: 11233: 11228: 11223: 11218: 11213: 11208: 11203: 11198: 11193: 11188: 11183: 11178: 11173: 11168: 11163: 11158: 11156:Butyrylcholine 11153: 11148: 11143: 11138: 11133: 11128: 11123: 11118: 11113: 11108: 11103: 11098: 11093: 11088: 11083: 11078: 11073: 11068: 11062: 11060: 11040: 11029: 11028: 11018: 11017: 11010: 11003: 10995: 10986: 10985: 10983: 10982: 10975: 10968: 10957: 10954: 10953: 10951: 10950: 10938: 10937: 10927: 10922: 10917: 10912: 10907: 10902: 10897: 10892: 10887: 10882: 10877: 10872: 10867: 10862: 10857: 10852: 10847: 10842: 10834: 10829: 10824: 10819: 10807: 10802: 10797: 10792: 10787: 10782: 10777: 10772: 10767: 10762: 10760:Methoxyflurane 10757: 10752: 10747: 10742: 10737: 10732: 10727: 10722: 10717: 10712: 10707: 10695: 10690: 10678: 10673: 10668: 10656: 10651: 10646: 10641: 10636: 10631: 10626: 10621: 10616: 10611: 10606: 10601: 10592: 10587: 10582: 10577: 10572: 10567: 10562: 10557: 10552: 10547: 10542: 10537: 10532: 10527: 10522: 10517: 10512: 10507: 10505:Nitromemantine 10502: 10497: 10492: 10487: 10482: 10477: 10472: 10467: 10462: 10457: 10452: 10447: 10442: 10440:Levomethorphan 10437: 10432: 10427: 10422: 10417: 10412: 10407: 10402: 10397: 10392: 10387: 10382: 10377: 10372: 10367: 10362: 10360:Dieticyclidine 10357: 10352: 10347: 10342: 10340:Dextrallorphan 10337: 10332: 10327: 10322: 10317: 10312: 10307: 10302: 10297: 10295:Argiotoxin-636 10292: 10287: 10282: 10277: 10272: 10267: 10262: 10257: 10252: 10247: 10242: 10237: 10232: 10220: 10215: 10210: 10208:Diaminopropane 10205: 10200: 10188: 10183: 10178: 10173: 10168: 10163: 10158: 10153: 10148: 10143: 10138: 10136:Kynurenic acid 10133: 10128: 10123: 10118: 10113: 10108: 10100: 10095: 10090: 10085: 10080: 10075: 10070: 10065: 10060: 10055: 10050: 10038: 10033: 10028: 10023: 10018: 10013: 10008: 10003: 9998: 9993: 9988: 9983: 9978: 9973: 9968: 9963: 9958: 9953: 9948: 9943: 9938: 9926: 9925: 9920: 9915: 9910: 9905: 9900: 9895: 9882: 9867: 9851: 9846: 9834: 9829: 9824: 9819: 9811: 9803: 9798: 9793: 9788: 9783: 9778: 9770: 9762: 9754: 9749: 9744: 9739: 9734: 9729: 9724: 9719: 9703: 9698: 9693: 9688: 9683: 9678: 9673: 9664: 9659: 9654: 9642: 9640: 9629: 9628: 9626: 9625: 9620: 9615: 9610: 9605: 9600: 9579: 9574: 9569: 9564: 9559: 9554: 9549: 9544: 9539: 9537:Kynurenic acid 9534: 9529: 9524: 9519: 9514: 9509: 9500: 9499: 9494: 9489: 9484: 9479: 9467: 9462: 9457: 9452: 9447: 9442: 9437: 9432: 9427: 9422: 9417: 9412: 9400: 9398: 9387: 9386: 9384: 9383: 9371: 9366: 9361: 9356: 9351: 9346: 9341: 9336: 9331: 9326: 9321: 9316: 9311: 9290: 9285: 9280: 9275: 9270: 9265: 9260: 9255: 9250: 9245: 9243:Kynurenic acid 9240: 9235: 9230: 9225: 9220: 9215: 9210: 9205: 9200: 9195: 9186: 9185: 9180: 9175: 9170: 9165: 9160: 9155: 9150: 9145: 9140: 9135: 9130: 9125: 9120: 9115: 9110: 9105: 9100: 9095: 9090: 9085: 9080: 9075: 9070: 9065: 9060: 9055: 9043: 9038: 9033: 9028: 9023: 9018: 9013: 9008: 9003: 8991: 8989: 8978: 8977: 8967: 8966: 8959: 8952: 8944: 8935: 8934: 8932: 8931: 8924: 8918: 8913: 8906: 8899: 8895: 8892: 8891: 8888: 8887: 8885: 8884: 8879: 8874: 8869: 8864: 8859: 8854: 8848: 8846: 8835: 8834: 8832: 8831: 8826: 8821: 8816: 8811: 8806: 8801: 8796: 8791: 8786: 8781: 8776: 8771: 8766: 8761: 8756: 8751: 8746: 8741: 8735: 8733: 8719: 8705: 8704: 8701: 8700: 8698: 8697: 8689: 8687: 8676: 8675: 8673: 8672: 8667: 8662: 8640: 8635: 8630: 8616: 8574: 8544: 8539: 8534: 8500: 8495: 8490: 8472: 8467: 8462: 8457: 8431: 8422: 8421: 8416: 8411: 8406: 8401: 8396: 8366: 8361: 8356: 8354:Nipecotic acid 8351: 8346: 8341: 8336: 8331: 8326: 8321: 8316: 8311: 8306: 8301: 8287: 8282: 8277: 8272: 8267: 8262: 8257: 8252: 8247: 8242: 8237: 8232: 8227: 8218: 8217: 8212: 8207: 8188:methoxyflurane 8149: 8119: 8114: 8109: 8104: 8099: 8094: 8089: 8063: 8058: 8053: 8048: 8045:ginsenoside-Rf 8034: 8029: 8019: 8014: 8009: 7995: 7990: 7985: 7944: 7943: 7938: 7933: 7928: 7923: 7921:Picolinic acid 7918: 7913: 7908: 7900: 7892: 7884: 7876: 7871: 7866: 7861: 7856: 7848: 7840: 7835: 7830: 7825: 7816: 7814: 7800: 7786: 7785: 7775: 7774: 7767: 7760: 7752: 7743: 7742: 7724: 7721: 7720: 7718: 7717: 7712: 7707: 7702: 7693: 7692: 7685:valerenic acid 7670: 7665: 7655: 7637: 7632: 7627: 7622: 7617: 7612: 7607: 7602: 7597: 7592: 7587: 7582: 7577: 7555: 7550: 7545: 7540: 7535: 7530: 7525: 7514:mefenamic acid 7503: 7498: 7493: 7488: 7483: 7461: 7456: 7451: 7446: 7441: 7436: 7431: 7426: 7423:sodium bromide 7408: 7398: 7393: 7388: 7383: 7377: 7375: 7371: 7370: 7368: 7367: 7362: 7357: 7352: 7347: 7342: 7337: 7332: 7327: 7322: 7317: 7312: 7307: 7302: 7297: 7292: 7290:Methoxypropane 7287: 7285:Methoxyflurane 7282: 7277: 7272: 7267: 7262: 7257: 7252: 7247: 7245:Ethyl chloride 7242: 7237: 7232: 7227: 7222: 7217: 7212: 7207: 7202: 7197: 7192: 7187: 7182: 7177: 7172: 7167: 7162: 7157: 7151: 7149: 7139: 7138: 7136: 7135: 7130: 7125: 7120: 7115: 7110: 7105: 7100: 7095: 7090: 7084: 7082: 7080:Quinazolinones 7076: 7075: 7073: 7072: 7067: 7062: 7057: 7051: 7049: 7043: 7042: 7040: 7039: 7034: 7029: 7024: 7018: 7016: 7010: 7009: 7007: 7006: 7001: 6996: 6990: 6988: 6982: 6981: 6979: 6978: 6973: 6968: 6963: 6958: 6953: 6948: 6943: 6938: 6933: 6928: 6923: 6918: 6913: 6908: 6903: 6898: 6893: 6888: 6883: 6878: 6873: 6868: 6863: 6858: 6853: 6848: 6843: 6838: 6833: 6823: 6822: 6817: 6812: 6807: 6802: 6797: 6792: 6787: 6775: 6774: 6769: 6764: 6759: 6754: 6742: 6741: 6736: 6731: 6726: 6721: 6716: 6704: 6702: 6696: 6695: 6693: 6692: 6687: 6682: 6677: 6672: 6667: 6662: 6657: 6652: 6647: 6642: 6637: 6632: 6627: 6622: 6617: 6612: 6607: 6602: 6597: 6592: 6587: 6582: 6577: 6572: 6567: 6561: 6556: 6551: 6546: 6541: 6536: 6531: 6525: 6523: 6517: 6516: 6514: 6513: 6508: 6503: 6498: 6493: 6488: 6482: 6480: 6474: 6473: 6471: 6470: 6465: 6460: 6455: 6450: 6445: 6440: 6435: 6430: 6425: 6420: 6415: 6410: 6405: 6400: 6394: 6392: 6385: 6384: 6382: 6381: 6376: 6371: 6365: 6363: 6357: 6356: 6354: 6353: 6348: 6338: 6333: 6328: 6323: 6318: 6313: 6308: 6303: 6298: 6293: 6288: 6283: 6277: 6275: 6269: 6268: 6266: 6265: 6260: 6255: 6250: 6245: 6240: 6235: 6230: 6225: 6220: 6215: 6210: 6205: 6200: 6195: 6190: 6185: 6180: 6175: 6170: 6165: 6159: 6157: 6151: 6150: 6148: 6147: 6142: 6137: 6132: 6127: 6122: 6117: 6112: 6107: 6102: 6097: 6092: 6087: 6082: 6077: 6072: 6067: 6062: 6057: 6052: 6047: 6042: 6037: 6032: 6027: 6022: 6017: 6012: 6007: 6002: 5997: 5992: 5987: 5982: 5977: 5972: 5967: 5962: 5957: 5952: 5947: 5942: 5937: 5932: 5927: 5922: 5917: 5912: 5907: 5902: 5897: 5892: 5887: 5882: 5877: 5872: 5867: 5862: 5857: 5852: 5847: 5842: 5837: 5832: 5827: 5822: 5817: 5812: 5807: 5802: 5797: 5792: 5787: 5782: 5777: 5772: 5767: 5762: 5757: 5752: 5747: 5742: 5737: 5732: 5727: 5722: 5717: 5712: 5707: 5702: 5697: 5692: 5687: 5682: 5677: 5672: 5667: 5662: 5657: 5652: 5647: 5642: 5637: 5632: 5627: 5622: 5617: 5612: 5607: 5601: 5599: 5593: 5592: 5590: 5589: 5584: 5579: 5574: 5569: 5564: 5559: 5554: 5549: 5544: 5539: 5534: 5529: 5524: 5519: 5514: 5509: 5504: 5502:Propylbarbital 5499: 5494: 5489: 5484: 5479: 5474: 5469: 5464: 5459: 5454: 5449: 5444: 5439: 5434: 5429: 5424: 5419: 5414: 5409: 5404: 5399: 5394: 5389: 5384: 5379: 5377:Crotylbarbital 5374: 5369: 5364: 5359: 5354: 5349: 5344: 5342:Brophebarbital 5339: 5337:Brallobarbital 5334: 5329: 5324: 5319: 5314: 5309: 5304: 5299: 5294: 5288: 5286: 5280: 5279: 5277: 5276: 5271: 5266: 5261: 5256: 5248: 5240: 5235: 5230: 5225: 5223:Methylpentynol 5220: 5215: 5210: 5205: 5200: 5195: 5185: 5180: 5175: 5170: 5164: 5162: 5156: 5155: 5149: 5142: 5141: 5134: 5127: 5119: 5113: 5110: 5109: 5095: 5094: 5092: 5091: 5086: 5081: 5076: 5071: 5069:Passion flower 5066: 5056: 5051: 5050: 5049: 5044: 5039: 5034: 5029: 5015: 5010: 5005: 5000: 4999: 4998: 4993: 4988: 4978: 4977: 4976: 4965: 4963: 4959: 4958: 4956: 4955: 4950: 4945: 4940: 4935: 4929: 4927: 4918: 4912: 4911: 4909: 4908: 4903: 4898: 4892: 4890: 4884: 4883: 4881: 4880: 4875: 4870: 4865: 4859: 4857: 4851: 4850: 4847: 4846: 4844: 4843: 4837: 4835: 4831: 4830: 4828: 4827: 4826: 4825: 4819: 4814: 4804: 4803: 4802: 4796: 4794:Chlorpromazine 4785: 4783: 4781:Antipsychotics 4777: 4776: 4774: 4773: 4772: 4771: 4765: 4755: 4754: 4753: 4747: 4742: 4732: 4726: 4724: 4715: 4711: 4706: 4705: 4703: 4702: 4697: 4692: 4687: 4682: 4677: 4672: 4667: 4661: 4659: 4654: 4649: 4648: 4645: 4644: 4642: 4641: 4640: 4639: 4633: 4628: 4618: 4617: 4616: 4610: 4608:Chlorpromazine 4599: 4597: 4595:Antipsychotics 4591: 4590: 4588: 4587: 4586: 4585: 4579: 4569: 4568: 4567: 4561: 4556: 4546: 4545: 4544: 4539: 4534: 4523: 4521: 4515: 4514: 4512: 4511: 4506: 4501: 4496: 4491: 4486: 4481: 4476: 4471: 4469:Cyproheptadine 4466: 4460: 4458: 4456:Antihistamines 4449: 4445: 4440: 4439: 4437: 4436: 4431: 4426: 4421: 4416: 4413:sodium oxybate 4406: 4401: 4396: 4391: 4386: 4384:1,4-Butanediol 4380: 4378: 4374: 4369: 4368: 4365: 4364: 4362: 4361: 4360: 4359: 4357:Valerenic acid 4354: 4349: 4339: 4334: 4333: 4332: 4327: 4322: 4312: 4307: 4302: 4297: 4292: 4287: 4282: 4277: 4272: 4267: 4262: 4257: 4256: 4255: 4253:Sodium bromide 4250: 4245: 4234: 4229: 4223: 4221: 4217: 4216: 4214: 4213: 4208: 4203: 4198: 4193: 4188: 4183: 4178: 4173: 4168: 4162: 4160: 4158:Quinazolinones 4154: 4153: 4151: 4150: 4145: 4140: 4135: 4129: 4127: 4121: 4120: 4118: 4117: 4111: 4109: 4103: 4102: 4100: 4099: 4094: 4089: 4084: 4079: 4074: 4069: 4064: 4059: 4054: 4049: 4043: 4041: 4035: 4034: 4032: 4031: 4026: 4021: 4016: 4011: 4006: 4001: 3996: 3990: 3988: 3982: 3981: 3979: 3978: 3973: 3968: 3963: 3958: 3953: 3947: 3945: 3939: 3938: 3936: 3935: 3930: 3925: 3919: 3917: 3911: 3910: 3908: 3907: 3902: 3897: 3892: 3887: 3882: 3877: 3872: 3867: 3861: 3859: 3853: 3852: 3850: 3849: 3844: 3839: 3834: 3829: 3824: 3819: 3814: 3809: 3804: 3799: 3794: 3789: 3784: 3779: 3774: 3769: 3764: 3759: 3754: 3749: 3744: 3738: 3736: 3730: 3729: 3727: 3726: 3721: 3716: 3711: 3706: 3701: 3696: 3691: 3686: 3681: 3679:Propylbarbital 3676: 3671: 3666: 3661: 3656: 3651: 3646: 3641: 3636: 3631: 3626: 3621: 3616: 3611: 3606: 3601: 3595: 3593: 3587: 3586: 3584: 3583: 3578: 3576:Methylpentynol 3573: 3568: 3563: 3558: 3553: 3547: 3545: 3536: 3532: 3527: 3526: 3510: 3509: 3502: 3495: 3487: 3478: 3477: 3474: 3473: 3472: 3471: 3468: 3457: 3451: 3445: 3444: 3441: 3440: 3437: 3436: 3434: 3433: 3428: 3422: 3420: 3416: 3415: 3413: 3412: 3407: 3402: 3396: 3394: 3388: 3387: 3385: 3384: 3379: 3374: 3369: 3363: 3361: 3355: 3354: 3352: 3351: 3346: 3340: 3335: 3330: 3325: 3320: 3315: 3310: 3304: 3302: 3296: 3295: 3293: 3292: 3287: 3282: 3277: 3271: 3269: 3263: 3262: 3260: 3259: 3254: 3249: 3244: 3239: 3234: 3229: 3223: 3221: 3215: 3214: 3212: 3211: 3206: 3201: 3195: 3193: 3184: 3178: 3177: 3175: 3174: 3169: 3164: 3159: 3154: 3149: 3147:Methoxypropane 3144: 3142:Methoxyflurane 3139: 3134: 3129: 3124: 3119: 3114: 3109: 3104: 3099: 3093: 3091: 3085: 3084: 3072: 3071: 3064: 3057: 3049: 3043: 3042: 3025: 3018: 3017:External links 3015: 3012: 3011: 2970: 2967:on 2011-05-01. 2956: 2932: 2929:on 2011-05-01. 2897: 2894:on 2011-05-13. 2884:ASA Newsletter 2870: 2867:on 2011-05-01. 2852: 2803: 2762: 2736: 2706: 2685:(3): 403–411. 2679:Anesthesiology 2665: 2638: 2607: 2581: 2556: 2531: 2502: 2471: 2422: 2395: 2375: 2336: 2329: 2311: 2293: 2279: 2254: 2224: 2194: 2173: 2152: 2131: 2098: 2068: 2019: 1975: 1944: 1895: 1881: 1861: 1832:(2): 106–112. 1812: 1787: 1762: 1748:978-1493919512 1747: 1721: 1699: 1668: 1640: 1625: 1593: 1565: 1538:Anesthesiology 1521: 1478: 1456:(2023-03-31). 1444: 1443: 1441: 1438: 1437: 1436: 1429: 1426: 1384: 1381: 1361:pentoxifylline 1325: 1322: 1308:Although each 1262: 1259: 1222: 1219: 1193: 1190: 1173: 1170: 1165: 1161: 1152: 1145:5-HT3 receptor 1134: 1117:Main article: 1114: 1111: 1094: 1091: 1075: 1072: 1016: 1013: 984: 981: 975:In refractory 972: 969: 951: 944:brain swelling 935: 932: 836: 833: 831: 828: 813:European Union 741: 740: 723: 722: 720: 719: 716: 714: 711: 703: 702: 701: 698: 697: 695: 694: 691: 683: 682: 681: 678: 677: 672: 666: 665: 663: 662: 654: 652: 644: 643: 637: 631: 630: 624: 615: 609: 603: 598: 592: 591: 587: 586: 576: 568: 567: 565: 564: 551: 549: 536: 535: 533: 532: 524: 522: 516: 515: 513: 512: 504: 502: 496: 495: 493: 492: 484: 482: 476: 475: 473: 472: 464: 462: 456: 455: 453: 452: 444: 442: 436: 435: 433: 432: 424: 422: 416: 415: 413: 412: 404: 402: 391: 390: 388: 387: 376: 374: 368: 367: 365: 364: 361: 353: 352: 351: 348: 347: 343: 342: 339: 333: 332: 329: 320: 319: 316: 310: 309: 303: 297: 296: 291: 285: 284: 281: 275: 274: 267: 266: 264: 263: 251: 239: 228: 215: 201: 199: 193: 192: 188: 187: 185: 184: 161: 159: 153: 152: 147: 141: 140: 137: 135:administration 129: 128: 126: 125: 123: 113: 111: 103: 102: 95: 85: 84: 81: 77: 76: 73: 67: 66: 62: 61: 53: 52: 15: 9: 6: 4: 3: 2: 12218: 12207: 12204: 12202: 12199: 12197: 12194: 12192: 12189: 12187: 12184: 12182: 12179: 12177: 12174: 12172: 12169: 12167: 12164: 12162: 12159: 12157: 12154: 12152: 12149: 12147: 12144: 12142: 12139: 12138: 12136: 12126: 12116: 12115: 12112: 12093: 12090: 12088: 12085: 12083: 12080: 12077: 12076: 12073: 12067: 12064: 12062: 12059: 12057: 12054: 12052: 12049: 12047: 12044: 12042: 12039: 12037: 12034: 12032: 12029: 12027: 12024: 12021: 12017: 12014: 12012: 12009: 12007: 12004: 12003: 12001: 11997: 11991: 11987: 11977: 11974: 11972: 11969: 11967: 11964: 11962: 11959: 11957: 11954: 11952: 11949: 11947: 11944: 11942: 11939: 11937: 11934: 11932: 11929: 11927: 11924: 11922: 11919: 11917: 11914: 11912: 11909: 11907: 11904: 11902: 11899: 11897: 11894: 11892: 11889: 11887: 11884: 11882: 11879: 11877: 11876:Phencyclidine 11874: 11872: 11869: 11867: 11864: 11862: 11859: 11857: 11854: 11852: 11849: 11847: 11846:Nitrous oxide 11844: 11842: 11839: 11837: 11834: 11832: 11829: 11827: 11824: 11822: 11819: 11817: 11814: 11812: 11809: 11807: 11804: 11802: 11799: 11797: 11794: 11792: 11789: 11787: 11786:Levomethadone 11784: 11782: 11779: 11777: 11774: 11772: 11769: 11767: 11764: 11762: 11759: 11757: 11754: 11752: 11749: 11747: 11744: 11742: 11739: 11737: 11734: 11732: 11731:Hexafluronium 11729: 11727: 11724: 11722: 11719: 11717: 11714: 11712: 11709: 11707: 11704: 11702: 11699: 11697: 11694: 11692: 11689: 11687: 11684: 11682: 11679: 11677: 11674: 11672: 11669: 11667: 11664: 11662: 11659: 11657: 11654: 11652: 11649: 11647: 11644: 11642: 11639: 11637: 11634: 11632: 11629: 11627: 11624: 11622: 11621:Decamethonium 11619: 11617: 11614: 11612: 11609: 11607: 11604: 11602: 11599: 11597: 11594: 11592: 11591:Cisatracurium 11589: 11587: 11584: 11582: 11579: 11577: 11574: 11572: 11569: 11567: 11564: 11561: 11557: 11553: 11552:Bungarotoxins 11550: 11548: 11545: 11542: 11538: 11537:pentobarbital 11534: 11531: 11529: 11526: 11524: 11521: 11519: 11516: 11514: 11511: 11509: 11506: 11504: 11501: 11499: 11496: 11493: 11489: 11485: 11481: 11480:α-Neurotoxins 11478: 11476: 11473: 11471: 11468: 11467: 11465: 11459: 11452: 11448: 11442: 11439: 11437: 11434: 11432: 11429: 11427: 11424: 11422: 11419: 11417: 11414: 11412: 11409: 11407: 11404: 11402: 11399: 11397: 11394: 11392: 11389: 11387: 11384: 11382: 11379: 11377: 11374: 11372: 11369: 11367: 11364: 11362: 11359: 11357: 11354: 11352: 11349: 11347: 11344: 11342: 11339: 11337: 11334: 11332: 11329: 11327: 11324: 11322: 11319: 11317: 11314: 11312: 11309: 11307: 11304: 11302: 11299: 11297: 11294: 11292: 11289: 11287: 11284: 11281: 11277: 11274: 11272: 11269: 11267: 11264: 11262: 11259: 11257: 11254: 11252: 11249: 11247: 11244: 11242: 11239: 11237: 11234: 11232: 11229: 11227: 11224: 11222: 11219: 11217: 11214: 11212: 11209: 11207: 11204: 11202: 11199: 11197: 11194: 11192: 11189: 11187: 11184: 11182: 11181:Decamethonium 11179: 11177: 11174: 11172: 11169: 11167: 11164: 11162: 11159: 11157: 11154: 11152: 11149: 11147: 11144: 11142: 11139: 11137: 11134: 11132: 11129: 11127: 11124: 11122: 11119: 11117: 11116:Acetylcholine 11114: 11112: 11109: 11107: 11104: 11102: 11099: 11097: 11094: 11092: 11089: 11087: 11084: 11082: 11079: 11077: 11074: 11072: 11069: 11067: 11064: 11063: 11061: 11055: 11048: 11044: 11041: 11036: 11030: 11026: 11023: 11016: 11011: 11009: 11004: 11002: 10997: 10996: 10993: 10981: 10980: 10976: 10974: 10973: 10969: 10967: 10966: 10963: 10959: 10958: 10955: 10949: 10946: 10943: 10940: 10939: 10935: 10931: 10930:Transcrocetin 10928: 10926: 10925:Psychotridine 10923: 10921: 10918: 10916: 10913: 10911: 10908: 10906: 10905:Niflumic acid 10903: 10901: 10898: 10896: 10893: 10891: 10888: 10886: 10883: 10881: 10878: 10876: 10873: 10871: 10868: 10866: 10863: 10861: 10858: 10856: 10853: 10851: 10848: 10846: 10843: 10841: 10835: 10833: 10830: 10828: 10825: 10823: 10820: 10818: 10815: 10811: 10808: 10806: 10803: 10801: 10798: 10796: 10793: 10791: 10788: 10786: 10783: 10781: 10778: 10776: 10773: 10771: 10768: 10766: 10765:Nitrous oxide 10763: 10761: 10758: 10756: 10753: 10751: 10748: 10746: 10743: 10741: 10738: 10736: 10733: 10731: 10730:Diethyl ether 10728: 10726: 10723: 10721: 10718: 10716: 10713: 10711: 10708: 10706: 10703: 10699: 10696: 10694: 10691: 10689: 10686: 10682: 10679: 10677: 10674: 10672: 10669: 10667: 10664: 10660: 10657: 10655: 10652: 10650: 10647: 10645: 10642: 10640: 10637: 10635: 10632: 10630: 10627: 10625: 10622: 10620: 10617: 10615: 10612: 10610: 10607: 10605: 10602: 10600: 10596: 10593: 10591: 10588: 10586: 10585:Tenocyclidine 10583: 10581: 10580:Tabernanthine 10578: 10576: 10573: 10571: 10570:Rolicyclidine 10568: 10566: 10563: 10561: 10558: 10556: 10553: 10551: 10548: 10546: 10545:Phencyclidine 10543: 10541: 10540:Phencyclamine 10538: 10536: 10533: 10531: 10528: 10526: 10523: 10521: 10518: 10516: 10513: 10511: 10508: 10506: 10503: 10501: 10498: 10496: 10493: 10491: 10488: 10486: 10483: 10481: 10478: 10476: 10475:Methoxetamine 10473: 10471: 10468: 10466: 10463: 10461: 10458: 10456: 10453: 10451: 10448: 10446: 10443: 10441: 10438: 10436: 10435:Levomethadone 10433: 10431: 10428: 10426: 10423: 10421: 10418: 10416: 10413: 10411: 10408: 10406: 10403: 10401: 10398: 10396: 10395:Fluorolintane 10393: 10391: 10388: 10386: 10383: 10381: 10378: 10376: 10373: 10371: 10368: 10366: 10363: 10361: 10358: 10356: 10353: 10351: 10348: 10346: 10343: 10341: 10338: 10336: 10333: 10331: 10328: 10326: 10323: 10321: 10318: 10316: 10313: 10311: 10308: 10306: 10303: 10301: 10298: 10296: 10293: 10291: 10288: 10286: 10283: 10281: 10278: 10276: 10273: 10271: 10268: 10266: 10263: 10261: 10258: 10256: 10253: 10251: 10248: 10246: 10243: 10241: 10238: 10236: 10233: 10231: 10228: 10224: 10221: 10219: 10216: 10214: 10211: 10209: 10206: 10204: 10201: 10199: 10196: 10192: 10189: 10187: 10184: 10182: 10179: 10177: 10174: 10172: 10169: 10167: 10164: 10162: 10159: 10157: 10154: 10152: 10149: 10147: 10144: 10142: 10139: 10137: 10134: 10132: 10129: 10127: 10124: 10122: 10119: 10117: 10114: 10112: 10109: 10107: 10101: 10099: 10096: 10094: 10091: 10089: 10086: 10084: 10081: 10079: 10076: 10074: 10071: 10069: 10066: 10064: 10061: 10059: 10056: 10054: 10051: 10049: 10046: 10042: 10039: 10037: 10034: 10032: 10029: 10027: 10024: 10022: 10019: 10017: 10014: 10012: 10009: 10007: 10004: 10002: 9999: 9997: 9994: 9992: 9989: 9987: 9984: 9982: 9979: 9977: 9976:Kaitocephalin 9974: 9972: 9969: 9967: 9964: 9962: 9959: 9957: 9954: 9952: 9949: 9947: 9944: 9942: 9939: 9937: 9934: 9931: 9928: 9927: 9924: 9921: 9919: 9916: 9914: 9911: 9909: 9906: 9904: 9901: 9899: 9896: 9893: 9889: 9883: 9880: 9873: 9868: 9866: 9864: 9859: 9855: 9852: 9850: 9847: 9845: 9842: 9838: 9835: 9833: 9830: 9828: 9825: 9823: 9820: 9818: 9812: 9810: 9804: 9802: 9799: 9797: 9794: 9792: 9789: 9787: 9784: 9782: 9779: 9777: 9771: 9769: 9763: 9761: 9755: 9753: 9750: 9748: 9745: 9743: 9740: 9738: 9735: 9733: 9730: 9728: 9725: 9723: 9720: 9718: 9711: 9707: 9704: 9702: 9699: 9697: 9694: 9692: 9689: 9687: 9684: 9682: 9681:Ibotenic acid 9679: 9677: 9674: 9672: 9665: 9663: 9660: 9658: 9655: 9653: 9650: 9647: 9644: 9643: 9641: 9636: 9630: 9624: 9621: 9619: 9616: 9614: 9611: 9609: 9606: 9604: 9601: 9598: 9594: 9593:pentobarbital 9590: 9587: 9583: 9580: 9578: 9575: 9573: 9570: 9568: 9565: 9563: 9560: 9558: 9555: 9553: 9550: 9548: 9545: 9543: 9540: 9538: 9535: 9533: 9532:Kaitocephalin 9530: 9528: 9525: 9523: 9520: 9518: 9515: 9513: 9510: 9508: 9505: 9502: 9501: 9498: 9495: 9493: 9490: 9488: 9485: 9483: 9480: 9478: 9477:Cyclothiazide 9475: 9471: 9468: 9466: 9463: 9461: 9458: 9456: 9453: 9451: 9448: 9446: 9445:Ibotenic acid 9443: 9441: 9438: 9436: 9433: 9431: 9428: 9426: 9423: 9421: 9418: 9416: 9413: 9411: 9408: 9405: 9402: 9401: 9399: 9394: 9388: 9382: 9379: 9375: 9372: 9370: 9367: 9365: 9362: 9360: 9357: 9355: 9352: 9350: 9347: 9345: 9342: 9340: 9337: 9335: 9332: 9330: 9327: 9325: 9322: 9320: 9317: 9315: 9312: 9309: 9305: 9304:pentobarbital 9301: 9298: 9294: 9291: 9289: 9286: 9284: 9281: 9279: 9276: 9274: 9271: 9269: 9266: 9264: 9261: 9259: 9256: 9254: 9251: 9249: 9246: 9244: 9241: 9239: 9238:Kaitocephalin 9236: 9234: 9231: 9229: 9226: 9224: 9221: 9219: 9216: 9214: 9211: 9209: 9206: 9204: 9201: 9199: 9196: 9194: 9191: 9188: 9187: 9184: 9181: 9179: 9176: 9174: 9171: 9169: 9166: 9164: 9161: 9159: 9156: 9154: 9151: 9149: 9146: 9144: 9141: 9139: 9136: 9134: 9131: 9129: 9126: 9124: 9121: 9119: 9116: 9114: 9111: 9109: 9106: 9104: 9101: 9099: 9096: 9094: 9091: 9089: 9086: 9084: 9081: 9079: 9076: 9074: 9071: 9069: 9066: 9064: 9061: 9059: 9058:Cyclothiazide 9056: 9054: 9051: 9047: 9044: 9042: 9039: 9037: 9034: 9032: 9031:Ibotenic acid 9029: 9027: 9024: 9022: 9019: 9017: 9014: 9012: 9009: 9007: 9004: 9002: 8999: 8996: 8993: 8992: 8990: 8985: 8979: 8975: 8972: 8965: 8960: 8958: 8953: 8951: 8946: 8945: 8942: 8930: 8929: 8925: 8923: 8922: 8914: 8912: 8911: 8907: 8905: 8904: 8900: 8897: 8896: 8893: 8883: 8880: 8878: 8875: 8873: 8870: 8868: 8865: 8863: 8860: 8858: 8855: 8853: 8850: 8849: 8847: 8842: 8836: 8830: 8827: 8825: 8822: 8820: 8817: 8815: 8812: 8810: 8807: 8805: 8802: 8800: 8797: 8795: 8792: 8790: 8787: 8785: 8782: 8780: 8777: 8775: 8772: 8770: 8767: 8765: 8762: 8760: 8757: 8755: 8752: 8750: 8747: 8745: 8742: 8740: 8737: 8736: 8734: 8729: 8723: 8720: 8716: 8710: 8706: 8695: 8691: 8690: 8688: 8683: 8677: 8671: 8668: 8666: 8663: 8660: 8656: 8652: 8648: 8644: 8641: 8639: 8636: 8634: 8631: 8628: 8624: 8620: 8617: 8614: 8610: 8606: 8602: 8598: 8594: 8593:levomethadone 8590: 8586: 8582: 8578: 8575: 8572: 8568: 8564: 8560: 8556: 8552: 8548: 8545: 8543: 8540: 8538: 8535: 8532: 8528: 8524: 8520: 8516: 8512: 8508: 8504: 8501: 8499: 8496: 8494: 8491: 8488: 8484: 8480: 8476: 8473: 8471: 8468: 8466: 8463: 8461: 8458: 8455: 8451: 8450:flunitrazepam 8447: 8443: 8439: 8435: 8432: 8430: 8427: 8424: 8423: 8420: 8417: 8415: 8412: 8410: 8407: 8405: 8402: 8400: 8397: 8394: 8390: 8386: 8382: 8378: 8374: 8370: 8367: 8365: 8362: 8360: 8357: 8355: 8352: 8350: 8347: 8345: 8342: 8340: 8337: 8335: 8332: 8330: 8329:Isostrychnine 8327: 8325: 8322: 8320: 8317: 8315: 8312: 8310: 8307: 8305: 8302: 8299: 8295: 8291: 8288: 8286: 8283: 8281: 8278: 8276: 8273: 8271: 8268: 8266: 8263: 8261: 8258: 8256: 8253: 8251: 8248: 8246: 8243: 8241: 8238: 8236: 8233: 8231: 8228: 8226: 8223: 8220: 8219: 8216: 8213: 8211: 8208: 8205: 8201: 8197: 8193: 8189: 8185: 8181: 8177: 8173: 8169: 8165: 8161: 8157: 8153: 8150: 8147: 8143: 8139: 8135: 8131: 8127: 8123: 8120: 8118: 8115: 8113: 8110: 8108: 8105: 8103: 8100: 8098: 8095: 8093: 8092:Nitrous oxide 8090: 8087: 8083: 8079: 8075: 8071: 8067: 8064: 8062: 8059: 8057: 8054: 8052: 8049: 8046: 8042: 8038: 8035: 8033: 8030: 8027: 8023: 8020: 8018: 8015: 8013: 8010: 8007: 8003: 8002:pentobarbital 7999: 7996: 7994: 7991: 7989: 7986: 7983: 7979: 7975: 7971: 7969: 7964: 7960: 7956: 7952: 7949: 7946: 7945: 7942: 7939: 7937: 7934: 7932: 7931:Quisqualamine 7929: 7927: 7924: 7922: 7919: 7917: 7914: 7912: 7909: 7907: 7901: 7899: 7893: 7891: 7885: 7883: 7877: 7875: 7872: 7870: 7867: 7865: 7862: 7860: 7857: 7855: 7849: 7847: 7841: 7839: 7836: 7834: 7831: 7829: 7826: 7824: 7821: 7818: 7817: 7815: 7810: 7804: 7801: 7797: 7791: 7787: 7783: 7780: 7773: 7768: 7766: 7761: 7759: 7754: 7753: 7750: 7740: 7739: 7735: 7731: 7728: 7722: 7716: 7713: 7711: 7708: 7706: 7703: 7701: 7698: 7695: 7694: 7690: 7686: 7682: 7681:isovaleramide 7678: 7674: 7671: 7669: 7666: 7663: 7659: 7656: 7653: 7649: 7645: 7641: 7638: 7636: 7633: 7631: 7628: 7626: 7623: 7621: 7618: 7616: 7613: 7611: 7608: 7606: 7603: 7601: 7598: 7596: 7593: 7591: 7588: 7586: 7583: 7581: 7578: 7575: 7571: 7567: 7563: 7559: 7556: 7554: 7551: 7549: 7546: 7544: 7541: 7539: 7536: 7534: 7531: 7529: 7526: 7523: 7519: 7518:niflumic acid 7515: 7511: 7507: 7504: 7502: 7499: 7497: 7494: 7492: 7489: 7487: 7484: 7481: 7477: 7473: 7469: 7465: 7462: 7460: 7457: 7455: 7452: 7450: 7447: 7445: 7444:Clomethiazole 7442: 7440: 7439:Chlormezanone 7437: 7435: 7432: 7430: 7429:Carbamazepine 7427: 7424: 7420: 7416: 7412: 7409: 7406: 7402: 7399: 7397: 7394: 7392: 7389: 7387: 7384: 7382: 7379: 7378: 7376: 7372: 7366: 7363: 7361: 7358: 7356: 7353: 7351: 7348: 7346: 7343: 7341: 7338: 7336: 7333: 7331: 7328: 7326: 7323: 7321: 7318: 7316: 7313: 7311: 7308: 7306: 7305:Nitrous oxide 7303: 7301: 7298: 7296: 7293: 7291: 7288: 7286: 7283: 7281: 7278: 7276: 7273: 7271: 7268: 7266: 7263: 7261: 7258: 7256: 7253: 7251: 7248: 7246: 7243: 7241: 7238: 7236: 7235:Diethyl ether 7233: 7231: 7228: 7226: 7223: 7221: 7218: 7216: 7213: 7211: 7208: 7206: 7203: 7201: 7198: 7196: 7193: 7191: 7188: 7186: 7183: 7181: 7178: 7176: 7173: 7171: 7168: 7166: 7163: 7161: 7158: 7156: 7153: 7152: 7150: 7148: 7144: 7140: 7134: 7131: 7129: 7126: 7124: 7121: 7119: 7116: 7114: 7111: 7109: 7106: 7104: 7101: 7099: 7096: 7094: 7091: 7089: 7086: 7085: 7083: 7081: 7077: 7071: 7068: 7066: 7063: 7061: 7058: 7056: 7053: 7052: 7050: 7048: 7044: 7038: 7037:Pyrithyldione 7035: 7033: 7030: 7028: 7025: 7023: 7020: 7019: 7017: 7015: 7011: 7005: 7002: 7000: 6997: 6995: 6992: 6991: 6989: 6987: 6983: 6977: 6974: 6972: 6969: 6967: 6964: 6962: 6959: 6957: 6954: 6952: 6949: 6947: 6944: 6942: 6939: 6937: 6934: 6932: 6929: 6927: 6924: 6922: 6919: 6917: 6914: 6912: 6909: 6907: 6904: 6902: 6899: 6897: 6894: 6892: 6889: 6887: 6884: 6882: 6879: 6877: 6874: 6872: 6869: 6867: 6864: 6862: 6859: 6857: 6854: 6852: 6849: 6847: 6844: 6842: 6839: 6837: 6834: 6832: 6828: 6825: 6824: 6821: 6818: 6816: 6813: 6811: 6808: 6806: 6803: 6801: 6798: 6796: 6793: 6791: 6788: 6786: 6782: 6781: 6777: 6776: 6773: 6770: 6768: 6765: 6763: 6760: 6758: 6755: 6753: 6749: 6748: 6744: 6743: 6740: 6737: 6735: 6732: 6730: 6727: 6725: 6722: 6720: 6717: 6715: 6711: 6710: 6706: 6705: 6703: 6701: 6697: 6691: 6688: 6686: 6683: 6681: 6678: 6676: 6673: 6671: 6668: 6666: 6663: 6661: 6658: 6656: 6653: 6651: 6648: 6646: 6643: 6641: 6638: 6636: 6633: 6631: 6628: 6626: 6623: 6621: 6618: 6616: 6613: 6611: 6608: 6606: 6603: 6601: 6598: 6596: 6593: 6591: 6588: 6586: 6583: 6581: 6578: 6576: 6573: 6571: 6568: 6566: 6562: 6560: 6557: 6555: 6552: 6550: 6547: 6545: 6542: 6540: 6537: 6535: 6532: 6530: 6527: 6526: 6524: 6522: 6518: 6512: 6509: 6507: 6504: 6502: 6499: 6497: 6494: 6492: 6489: 6487: 6484: 6483: 6481: 6479: 6475: 6469: 6466: 6464: 6461: 6459: 6456: 6454: 6451: 6449: 6446: 6444: 6441: 6439: 6436: 6434: 6431: 6429: 6426: 6424: 6421: 6419: 6416: 6414: 6411: 6409: 6406: 6404: 6401: 6399: 6396: 6395: 6393: 6390: 6386: 6380: 6377: 6375: 6372: 6370: 6367: 6366: 6364: 6362: 6358: 6352: 6349: 6346: 6342: 6339: 6337: 6334: 6332: 6329: 6327: 6324: 6322: 6319: 6317: 6314: 6312: 6309: 6307: 6304: 6302: 6299: 6297: 6294: 6292: 6289: 6287: 6284: 6282: 6279: 6278: 6276: 6274: 6270: 6264: 6261: 6259: 6256: 6254: 6251: 6249: 6246: 6244: 6243:Phenprobamate 6241: 6239: 6236: 6234: 6231: 6229: 6226: 6224: 6221: 6219: 6216: 6214: 6211: 6209: 6208:Hexapropymate 6206: 6204: 6201: 6199: 6196: 6194: 6191: 6189: 6186: 6184: 6183:Difebarbamate 6181: 6179: 6176: 6174: 6171: 6169: 6166: 6164: 6161: 6160: 6158: 6156: 6152: 6146: 6143: 6141: 6138: 6136: 6133: 6131: 6128: 6126: 6123: 6121: 6118: 6116: 6113: 6111: 6108: 6106: 6103: 6101: 6098: 6096: 6093: 6091: 6088: 6086: 6083: 6081: 6078: 6076: 6073: 6071: 6068: 6066: 6063: 6061: 6058: 6056: 6053: 6051: 6048: 6046: 6043: 6041: 6038: 6036: 6033: 6031: 6028: 6026: 6023: 6021: 6018: 6016: 6013: 6011: 6008: 6006: 6003: 6001: 5998: 5996: 5995:Nortetrazepam 5993: 5991: 5988: 5986: 5983: 5981: 5978: 5976: 5973: 5971: 5968: 5966: 5963: 5961: 5958: 5956: 5953: 5951: 5948: 5946: 5943: 5941: 5938: 5936: 5933: 5931: 5928: 5926: 5923: 5921: 5918: 5916: 5913: 5911: 5908: 5906: 5903: 5901: 5898: 5896: 5893: 5891: 5888: 5886: 5883: 5881: 5878: 5876: 5873: 5871: 5868: 5866: 5863: 5861: 5858: 5856: 5855:Flutoprazepam 5853: 5851: 5848: 5846: 5843: 5841: 5838: 5836: 5835:Flunitrazolam 5833: 5831: 5830:Flunitrazepam 5828: 5826: 5823: 5821: 5820:Flubromazolam 5818: 5816: 5815:Flubromazepam 5813: 5811: 5808: 5806: 5803: 5801: 5798: 5796: 5793: 5791: 5788: 5786: 5783: 5781: 5778: 5776: 5773: 5771: 5768: 5766: 5763: 5761: 5758: 5756: 5753: 5751: 5748: 5746: 5743: 5741: 5738: 5736: 5733: 5731: 5728: 5726: 5723: 5721: 5718: 5716: 5715:Cloniprazepam 5713: 5711: 5708: 5706: 5703: 5701: 5698: 5696: 5693: 5691: 5688: 5686: 5683: 5681: 5678: 5676: 5673: 5671: 5668: 5666: 5663: 5661: 5658: 5656: 5653: 5651: 5648: 5646: 5643: 5641: 5638: 5636: 5633: 5631: 5628: 5626: 5623: 5621: 5618: 5616: 5613: 5611: 5608: 5606: 5605:2-Oxoquazepam 5603: 5602: 5600: 5598: 5594: 5588: 5585: 5583: 5580: 5578: 5575: 5573: 5570: 5568: 5565: 5563: 5560: 5558: 5555: 5553: 5550: 5548: 5547:Thialbarbital 5545: 5543: 5542:Tetrabarbital 5540: 5538: 5535: 5533: 5530: 5528: 5527:Spirobarbital 5525: 5523: 5520: 5518: 5515: 5513: 5510: 5508: 5507:Proxibarbital 5505: 5503: 5500: 5498: 5497:Propallylonal 5495: 5493: 5490: 5488: 5485: 5483: 5480: 5478: 5477:Phenobarbital 5475: 5473: 5470: 5468: 5467:Pentobarbital 5465: 5463: 5460: 5458: 5457:Narcobarbital 5455: 5453: 5450: 5448: 5445: 5443: 5440: 5438: 5435: 5433: 5430: 5428: 5425: 5423: 5422:Heptobarbital 5420: 5418: 5415: 5413: 5410: 5408: 5405: 5403: 5400: 5398: 5395: 5393: 5392:Difebarbamate 5390: 5388: 5385: 5383: 5382:Cyclobarbital 5380: 5378: 5375: 5373: 5370: 5368: 5365: 5363: 5360: 5358: 5355: 5353: 5350: 5348: 5345: 5343: 5340: 5338: 5335: 5333: 5330: 5328: 5327:Benzobarbital 5325: 5323: 5320: 5318: 5315: 5313: 5310: 5308: 5305: 5303: 5300: 5298: 5295: 5293: 5290: 5289: 5287: 5285: 5281: 5275: 5272: 5270: 5267: 5265: 5262: 5260: 5257: 5255: 5253: 5249: 5247: 5245: 5241: 5239: 5236: 5234: 5231: 5229: 5226: 5224: 5221: 5219: 5216: 5214: 5211: 5209: 5206: 5204: 5201: 5199: 5198:Ethchlorvynol 5196: 5193: 5189: 5186: 5184: 5181: 5179: 5176: 5174: 5171: 5169: 5166: 5165: 5163: 5161: 5157: 5153: 5140: 5135: 5133: 5128: 5126: 5121: 5120: 5117: 5111: 5107: 5102: 5090: 5087: 5085: 5082: 5080: 5077: 5075: 5072: 5070: 5067: 5064: 5060: 5057: 5055: 5052: 5048: 5047:Methocarbamol 5045: 5043: 5040: 5038: 5037:Mephenoxalone 5035: 5033: 5030: 5028: 5027:Chlorphenesin 5025: 5024: 5023: 5019: 5016: 5014: 5011: 5009: 5006: 5004: 5001: 4997: 4996:Phenaglycodol 4994: 4992: 4989: 4987: 4984: 4983: 4982: 4979: 4975: 4972: 4971: 4970: 4967: 4966: 4964: 4960: 4954: 4951: 4949: 4946: 4944: 4941: 4939: 4936: 4934: 4931: 4930: 4928: 4926: 4913: 4907: 4904: 4902: 4899: 4897: 4894: 4893: 4891: 4889: 4885: 4879: 4876: 4874: 4871: 4869: 4866: 4864: 4861: 4860: 4858: 4856: 4852: 4842: 4839: 4838: 4836: 4832: 4823: 4820: 4818: 4815: 4813: 4810: 4809: 4808: 4805: 4800: 4797: 4795: 4792: 4791: 4790: 4787: 4786: 4784: 4782: 4778: 4769: 4766: 4764: 4761: 4760: 4759: 4756: 4751: 4748: 4746: 4743: 4741: 4740:Amitriptyline 4738: 4737: 4736: 4733: 4731: 4728: 4727: 4725: 4723: 4719: 4716: 4714: 4707: 4701: 4698: 4696: 4693: 4691: 4688: 4686: 4683: 4681: 4678: 4676: 4673: 4671: 4668: 4666: 4663: 4662: 4660: 4658: 4650: 4637: 4634: 4632: 4629: 4627: 4624: 4623: 4622: 4619: 4614: 4611: 4609: 4606: 4605: 4604: 4601: 4600: 4598: 4596: 4592: 4583: 4580: 4578: 4575: 4574: 4573: 4570: 4565: 4562: 4560: 4557: 4555: 4554:Amitriptyline 4552: 4551: 4550: 4547: 4543: 4540: 4538: 4535: 4533: 4530: 4529: 4528: 4525: 4524: 4522: 4520: 4516: 4510: 4507: 4505: 4502: 4500: 4497: 4495: 4492: 4490: 4489:Methapyrilene 4487: 4485: 4482: 4480: 4477: 4475: 4472: 4470: 4467: 4465: 4462: 4461: 4459: 4457: 4453: 4450: 4448: 4441: 4435: 4432: 4430: 4427: 4425: 4422: 4420: 4417: 4414: 4410: 4407: 4405: 4402: 4400: 4397: 4395: 4394:Aceburic acid 4392: 4390: 4387: 4385: 4382: 4381: 4379: 4377: 4370: 4358: 4355: 4353: 4350: 4348: 4347:Isovaleramide 4345: 4344: 4343: 4342:Sesquiterpene 4340: 4338: 4335: 4331: 4328: 4326: 4323: 4321: 4318: 4317: 4316: 4313: 4311: 4308: 4306: 4303: 4301: 4298: 4296: 4293: 4291: 4288: 4286: 4283: 4281: 4280:Clomethiazole 4278: 4276: 4273: 4271: 4268: 4266: 4263: 4261: 4258: 4254: 4251: 4249: 4246: 4244: 4241: 4240: 4238: 4235: 4233: 4230: 4228: 4225: 4224: 4222: 4218: 4212: 4209: 4207: 4204: 4202: 4199: 4197: 4194: 4192: 4189: 4187: 4184: 4182: 4179: 4177: 4174: 4172: 4169: 4167: 4164: 4163: 4161: 4159: 4155: 4149: 4146: 4144: 4143:Pyrithyldione 4141: 4139: 4136: 4134: 4131: 4130: 4128: 4126: 4122: 4116: 4113: 4112: 4110: 4108: 4104: 4098: 4095: 4093: 4090: 4088: 4085: 4083: 4080: 4078: 4075: 4073: 4070: 4068: 4065: 4063: 4060: 4058: 4055: 4053: 4050: 4048: 4045: 4044: 4042: 4040: 4036: 4030: 4027: 4025: 4022: 4020: 4017: 4015: 4012: 4010: 4007: 4005: 4002: 4000: 3997: 3995: 3992: 3991: 3989: 3987: 3983: 3977: 3974: 3972: 3969: 3967: 3964: 3962: 3959: 3957: 3954: 3952: 3949: 3948: 3946: 3944: 3940: 3934: 3931: 3929: 3926: 3924: 3921: 3920: 3918: 3916: 3912: 3906: 3903: 3901: 3898: 3896: 3895:Phenprobamate 3893: 3891: 3890:Methocarbamol 3888: 3886: 3883: 3881: 3880:Hexapropymate 3878: 3876: 3873: 3871: 3868: 3866: 3863: 3862: 3860: 3858: 3854: 3848: 3845: 3843: 3840: 3838: 3835: 3833: 3830: 3828: 3825: 3823: 3820: 3818: 3815: 3813: 3810: 3808: 3805: 3803: 3800: 3798: 3797:Flutoprazepam 3795: 3793: 3790: 3788: 3785: 3783: 3782:Flunitrazepam 3780: 3778: 3777:Flunitrazolam 3775: 3773: 3772:Flubromazolam 3770: 3768: 3765: 3763: 3760: 3758: 3755: 3753: 3750: 3748: 3745: 3743: 3740: 3739: 3737: 3735: 3731: 3725: 3722: 3720: 3717: 3715: 3712: 3710: 3707: 3705: 3702: 3700: 3697: 3695: 3692: 3690: 3687: 3685: 3682: 3680: 3677: 3675: 3674:Phenobarbital 3672: 3670: 3667: 3665: 3664:Pentobarbital 3662: 3660: 3659:Narcobarbital 3657: 3655: 3652: 3650: 3649:Mephobarbital 3647: 3645: 3642: 3640: 3637: 3635: 3632: 3630: 3629:Cyclobarbital 3627: 3625: 3622: 3620: 3617: 3615: 3612: 3610: 3607: 3605: 3602: 3600: 3597: 3596: 3594: 3592: 3588: 3582: 3579: 3577: 3574: 3572: 3571:Ethchlorvynol 3569: 3567: 3564: 3562: 3559: 3557: 3554: 3552: 3549: 3548: 3546: 3544: 3540: 3537: 3535: 3528: 3523: 3519: 3515: 3508: 3503: 3501: 3496: 3494: 3489: 3488: 3485: 3469: 3467: 3464: 3463: 3461: 3458: 3455: 3452: 3450: 3447: 3446: 3442: 3432: 3429: 3427: 3424: 3423: 3421: 3417: 3411: 3408: 3406: 3403: 3401: 3398: 3397: 3395: 3393: 3389: 3383: 3380: 3378: 3377:Phencyclidine 3375: 3373: 3370: 3368: 3365: 3364: 3362: 3360: 3356: 3350: 3347: 3344: 3341: 3339: 3338:Phenoperidine 3336: 3334: 3331: 3329: 3326: 3324: 3321: 3319: 3316: 3314: 3311: 3309: 3306: 3305: 3303: 3301: 3297: 3291: 3288: 3286: 3283: 3281: 3278: 3276: 3273: 3272: 3270: 3268: 3264: 3258: 3255: 3253: 3250: 3248: 3245: 3243: 3242:Narcobarbital 3240: 3238: 3235: 3233: 3230: 3228: 3225: 3224: 3222: 3220: 3216: 3210: 3207: 3205: 3202: 3200: 3197: 3196: 3194: 3192: 3188: 3185: 3183: 3179: 3173: 3170: 3168: 3165: 3163: 3160: 3158: 3155: 3153: 3152:Nitrous oxide 3150: 3148: 3145: 3143: 3140: 3138: 3135: 3133: 3130: 3128: 3125: 3123: 3120: 3118: 3115: 3113: 3112:Diethyl ether 3110: 3108: 3105: 3103: 3100: 3098: 3095: 3094: 3092: 3090: 3086: 3081: 3077: 3070: 3065: 3063: 3058: 3056: 3051: 3050: 3047: 3040: 3039: 3034: 3030: 3026: 3024: 3021: 3020: 3007: 3003: 2998: 2993: 2989: 2985: 2981: 2974: 2963: 2959: 2957:0-8240-6525-5 2953: 2949: 2948: 2943: 2936: 2928: 2924: 2920: 2916: 2912: 2908: 2901: 2893: 2889: 2885: 2881: 2874: 2866: 2862: 2856: 2848: 2844: 2839: 2834: 2830: 2826: 2822: 2818: 2814: 2807: 2799: 2795: 2790: 2785: 2782:(1): 143–53. 2781: 2777: 2773: 2766: 2750: 2746: 2740: 2724: 2720: 2716: 2710: 2702: 2698: 2693: 2688: 2684: 2680: 2676: 2669: 2661: 2657: 2653: 2650:(in French). 2649: 2642: 2634: 2630: 2627:(3): 343–57. 2626: 2622: 2618: 2611: 2596: 2595:Texas Monthly 2592: 2585: 2571: 2567: 2560: 2546: 2542: 2535: 2521:on 2007-05-18 2520: 2516: 2512: 2506: 2498: 2494: 2490: 2486: 2482: 2475: 2467: 2463: 2458: 2453: 2449: 2445: 2442:(1): 98–107. 2441: 2437: 2433: 2426: 2418: 2414: 2410: 2406: 2399: 2391: 2390: 2385: 2379: 2371: 2367: 2363: 2359: 2355: 2351: 2347: 2340: 2332: 2326: 2322: 2315: 2307: 2303: 2297: 2289: 2283: 2268: 2264: 2258: 2243: 2239: 2235: 2228: 2212: 2208: 2204: 2198: 2190: 2189: 2184: 2177: 2169: 2168: 2163: 2156: 2141: 2135: 2121:on 2008-08-21 2120: 2116: 2112: 2105: 2103: 2088:on 2020-10-18 2087: 2083: 2079: 2072: 2064: 2060: 2055: 2050: 2046: 2042: 2038: 2034: 2030: 2023: 2015: 2011: 2007: 2003: 1999: 1995: 1991: 1987: 1979: 1963: 1959: 1955: 1948: 1940: 1936: 1931: 1926: 1922: 1918: 1914: 1910: 1906: 1899: 1884: 1882:9781455727148 1878: 1874: 1873: 1865: 1857: 1853: 1848: 1843: 1839: 1835: 1831: 1827: 1823: 1816: 1802: 1798: 1791: 1776: 1772: 1766: 1758: 1754: 1750: 1744: 1740: 1736: 1732: 1725: 1709: 1703: 1694: 1689: 1685: 1681: 1675: 1673: 1663: 1658: 1654: 1650: 1644: 1636: 1632: 1628: 1626:9789241209656 1622: 1617: 1612: 1608: 1603: 1597: 1588: 1583: 1579: 1575: 1569: 1561: 1557: 1552: 1547: 1544:(6): 474–80. 1543: 1539: 1535: 1528: 1526: 1517: 1513: 1509: 1505: 1501: 1497: 1493: 1489: 1482: 1467: 1463: 1459: 1455: 1449: 1445: 1435: 1434:Pentobarbital 1432: 1431: 1425: 1423: 1419: 1418: 1413: 1409: 1404: 1402: 1398: 1394: 1390: 1380: 1378: 1374: 1370: 1366: 1362: 1357: 1355: 1351: 1347: 1343: 1342:heart disease 1339: 1335: 1331: 1330:liver disease 1321: 1319: 1315: 1311: 1306: 1304: 1300: 1296: 1292: 1287: 1283: 1279: 1276:resulting in 1275: 1271: 1268: 1258: 1256: 1252: 1251:liver failure 1248: 1244: 1240: 1236: 1232: 1228: 1218: 1216: 1215:pentobarbital 1212: 1208: 1203: 1199: 1189: 1186: 1181: 1179: 1172:Controversies 1169: 1159: 1150: 1146: 1143:(nAChR), the 1142: 1138: 1130: 1126: 1120: 1110: 1108: 1104: 1103:Jan Bastiaans 1100: 1090: 1087: 1081: 1071: 1068: 1063: 1061: 1056: 1054: 1053:Kenneth Biros 1048: 1046: 1042: 1041: 1036: 1032: 1028: 1022: 1012: 1010: 1006: 1002: 996: 994: 990: 980: 978: 968: 965: 964:pentobarbital 961: 957: 949: 945: 941: 940:medical comas 931: 929: 925: 920: 916: 912: 907: 905: 902:). Since its 901: 897: 893: 889: 884: 882: 878: 873: 870: 866: 862: 859:, such as in 858: 854: 850: 846: 842: 827: 825: 821: 816: 814: 810: 806: 802: 798: 794: 790: 789:pentobarbital 786: 782: 779: 775: 771: 767: 763: 759: 755: 747: 737: 730: 724: 715: 710: 709: 706: 699: 690: 689: 686: 679: 676: 673: 671: 667: 660: 656: 655: 653: 650: 645: 638: 636: 632: 599: 597: 593: 588: 584: 580: 577: 575: 573:ECHA InfoCard 569: 561: 557: 556:DTXSID1021744 553: 552: 550: 541: 537: 530: 526: 525: 523: 521: 517: 510: 506: 505: 503: 501: 497: 490: 486: 485: 483: 481: 477: 470: 466: 465: 463: 461: 457: 450: 446: 445: 443: 441: 437: 430: 426: 425: 423: 421: 417: 410: 406: 405: 403: 396: 392: 384:(sodium salt) 382: 378: 377: 375: 373: 369: 360: 359: 356: 349: 344: 340: 338: 334: 330: 328: 321: 318:30–45 seconds 317: 315: 311: 307: 306:Pentobarbital 304: 302: 298: 295: 292: 290: 286: 282: 280: 276: 272: 268: 262: 252: 250: 240: 238: 229: 226: 216: 213: 203: 202: 200: 198: 194: 189: 181: 176: 171: 166: 163: 162: 160: 158: 154: 151: 148: 146: 142: 138: 136: 130: 124: 115: 114: 112: 110: 104: 100: 96: 94: 90: 86: 82: 78: 74: 72: 68: 65:Clinical data 63: 59: 54: 50: 45: 35: 28: 27:phenobarbital 24: 23:pentobarbital 19: 11961:Tubocurarine 11891:Promegestone 11886:Progesterone 11801:Mecamylamine 11611:Cyclopropane 11601:Coronaridine 11540: 11533:Barbiturates 11518:Anatruxonium 11488:α-cobratoxin 11331:Sazetidine A 11251:JNJ-39393406 11241:Ispronicline 10977: 10970: 10961: 10960: 10944: 10941: 10813: 10720:Cyclopropane 10701: 10684: 10662: 10598: 10550:Propoxyphene 10520:Orphenadrine 10425:Ketobemidone 10390:Eticyclidine 10325:Coronaridine 10310:ARL-15896-AR 10226: 10194: 10106:-Cycloserine 10088:Carisoprodol 10044: 9932: 9930:Antagonists: 9929: 9862: 9857: 9840: 9768:-Cycloserine 9709: 9648: 9645: 9596: 9589:Barbiturates 9585: 9562:Selurampanel 9517:Dasolampanel 9504:Antagonists: 9503: 9473: 9406: 9403: 9377: 9314:Cyclopropane 9307: 9300:Barbiturates 9296: 9268:Selurampanel 9218:Dasolampanel 9190:Antagonists: 9189: 9173:Pramiracetam 9049: 8997: 8994: 8926: 8915: 8908: 8901: 8627:picrotoxinin 8571:progesterone 8563:DHEA sulfate 8531:ginkgolide M 8527:ginkgolide J 8523:ginkgolide C 8519:ginkgolide B 8515:ginkgolide A 8487:nitrendipine 8425: 8222:Antagonists: 8221: 8097:Penicillin G 8041:ginsenosides 8005: 7998:Barbiturates 7967: 7947: 7828:β-ABA (BABA) 7819: 7726: 7725: 7696: 7553:Lavender oil 7295:Nitric oxide 7215:Cryofluorane 7160:Acetophenone 7118:Methaqualone 7113:Mecloqualone 7108:Mebroqualone 7098:Diproqualone 7093:Cloroqualone 7022:Glutethimide 6826: 6778: 6745: 6707: 6680:Testosterone 6645:Progesterone 6610:Hydroxydione 6559:Androsterone 6486:Acecarbromal 6391:constituents 6178:Cyclarbamate 6168:Carisoprodol 5940:Metaclazepam 5935:Menitrazepam 5925:Meclonazepam 5920:Lormetazepam 5850:Flutemazepam 5675:Ciclotizolam 5665:Carburazepam 5566: 5557:Thiobarbital 5517:Secobarbital 5482:Phetharbital 5462:Nealbarbital 5447:Methohexital 5432:Hexobarbital 5367:Butallylonal 5362:Butobarbital 5317:Barbexaclone 5312:Aprobarbital 5297:Allobarbital 5284:Barbiturates 5251: 5243: 5233:Petrichloral 5089:Valnoctamide 4991:Metaglycodol 4986:Fenpentadiol 4896:Daridorexant 4799:Thioridazine 4750:Trimipramine 4685:Medetomidine 4613:Thioridazine 4564:Trimipramine 4509:Propiomazine 4504:Promethazine 4310:Petrichloral 4295:Kavalactones 4227:Acetophenone 4196:Methaqualone 4191:Mecloqualone 4186:Mebroqualone 4176:Diproqualone 4171:Cloroqualone 4133:Glutethimide 4029:Progesterone 4019:Hydroxydione 3951:Acecarbromal 3865:Carisoprodol 3807:Lormetazepam 3792:Flutemazepam 3708: 3694:Secobarbital 3654:Methohexital 3644:Hexobarbital 3624:Butobarbital 3619:Butabarbital 3609:Aprobarbital 3599:Allobarbital 3591:Barbiturates 3410:Hydroxydione 3343:Remifentanil 3251: 3237:Methohexital 3232:Hexobarbital 3219:Barbiturates 3102:Cyclopropane 3089:Inhalational 3036: 2990:(3): 366–8. 2987: 2983: 2973: 2962:the original 2946: 2935: 2927:the original 2914: 2910: 2900: 2892:the original 2887: 2883: 2873: 2865:the original 2855: 2823:(4): 450–5. 2820: 2816: 2806: 2779: 2775: 2772:"Porphyrias" 2765: 2753:. Retrieved 2749:the original 2739: 2727:. Retrieved 2718: 2709: 2682: 2678: 2668: 2651: 2647: 2641: 2624: 2620: 2610: 2598:. Retrieved 2584: 2573:. Retrieved 2569: 2559: 2548:. Retrieved 2544: 2534: 2523:. Retrieved 2519:the original 2505: 2480: 2474: 2439: 2435: 2425: 2412: 2408: 2398: 2387: 2378: 2349: 2345: 2339: 2320: 2314: 2305: 2296: 2282: 2270:. Retrieved 2266: 2257: 2245:. Retrieved 2237: 2227: 2215:. Retrieved 2206: 2197: 2186: 2176: 2165: 2155: 2144:. Retrieved 2134: 2123:. Retrieved 2119:the original 2090:. Retrieved 2086:the original 2081: 2071: 2036: 2032: 2022: 1989: 1985: 1978: 1966:. Retrieved 1962:the original 1957: 1947: 1912: 1908: 1898: 1886:. Retrieved 1871: 1864: 1829: 1825: 1815: 1804:. Retrieved 1800: 1790: 1779:. Retrieved 1777:. 2013-10-03 1774: 1765: 1730: 1724: 1712:. Retrieved 1702: 1693:10665/345533 1683: 1662:10665/325771 1652: 1643: 1605: 1596: 1587:10665/70642/ 1577: 1568: 1541: 1537: 1491: 1487: 1481: 1470:. Retrieved 1448: 1415: 1405: 1386: 1358: 1327: 1307: 1297:, prolonged 1264: 1261:Side effects 1239:drug synergy 1224: 1195: 1182: 1175: 1122: 1096: 1083: 1064: 1057: 1049: 1038: 1024: 997: 986: 974: 937: 908: 890:elimination 885: 874: 863:. Following 838: 817: 793:thiobarbital 773: 769: 765: 757: 753: 752: 733:   727:   341:5–10 minutes 331:5.5–26 hours 324:Elimination 261:Schedule III 197:Legal status 191:Legal status 18: 12066:Pirisudanol 12031:Cyprodenate 12011:Adafenoxate 11926:Surugatoxin 11916:Sevoflurane 11871:Pentolinium 11851:Norketamine 11771:Laudanosine 11701:Erythravine 11691:Encenicline 11676:Dipyrandium 11646:Dextrorphan 11492:α-conotoxin 11451:Antagonists 11436:WAY-317,538 11431:Varenicline 11421:Tropisetron 11411:Tebanicline 11356:SSR-180,711 11321:Rivanicline 11311:Pozanicline 11306:PNU-282,987 11301:PNU-120,596 11296:PHA-709,829 11291:PHA-543,613 11231:Galantamine 11206:Epiboxidine 11201:Epibatidine 11121:Altinicline 10910:Pentamidine 10895:Minocycline 10875:Hodgkinsine 10845:Dexanabinol 10775:Sevoflurane 10629:Isoxsuprine 10624:Haloperidol 10604:Besonprodil 10565:Rimantadine 10515:Norketamine 10510:Noribogaine 10485:Milnacipran 10450:Levorphanol 10400:Gacyclidine 10370:Dizocilpine 10365:Diphenidine 10355:Dextrorphan 10275:Alaproclate 10218:Huperzine A 10171:Meprobamate 10131:Harkoseride 10026:Perzinfotel 9903:Plazinemdor 9450:Kainic acid 9435:Domoic acid 9381:Minocycline 9369:Sevoflurane 9046:Willardiine 9021:Domoic acid 8824:SSR-504,734 8819:SSR-103,800 8809:PF-03463275 8789:Mardepodect 8709:Transporter 8655:tropisetron 8597:levorphanol 8589:dextrorphan 8511:ginkgolides 8479:nicardipine 8334:Laudanosine 8255:Cacotheline 8245:Bicuculline 8192:sevoflurane 8142:tropisetron 8026:nicardipine 7869:Hypotaurine 7635:Stiripentol 7630:Seproxetine 7600:Niacinamide 7580:Loreclezole 7401:Avermectins 7365:Vinyl ether 7335:Sevoflurane 7315:Paraldehyde 7265:Halopropane 7088:Afloqualone 7070:Tracazolate 7065:ICI-190,622 7055:Cartazolate 7032:Piperidione 7027:Methyprylon 6994:Fospropofol 6916:Pipequaline 6724:Pazinaclone 6714:Eszopiclone 6570:Cholesterol 6554:Androstenol 6478:Monoureides 6458:Methysticin 6258:Tetrabamate 6238:Pentabamate 6228:Meprobamate 6198:Febarbamate 6163:Carisbamate 6115:Triflubazam 6105:Tolufazepam 6065:Rilmazafone 6060:Remimazolam 6035:Proflazepam 6020:Pivoxazepam 5980:Nitrazepate 5970:Nimetazepam 5905:Lopirazepam 5875:Haloxazolam 5825:Fludiazepam 5770:Doxefazepam 5745:Delorazepam 5725:Clotiazepam 5720:Clorazepate 5685:Cinolazepam 5582:Vinbarbital 5537:Tetrabamate 5492:Probarbital 5472:Phenallymal 5437:Metharbital 5412:Febarbamate 5307:Amobarbital 5208:Isopropanol 5178:Chloralodol 5074:Scopolamine 5018:Guaifenesin 5013:Fenadiazole 4969:Cannabidiol 4943:Mirogabalin 4901:Lemborexant 4878:Tasimelteon 4863:Agomelatine 4822:Risperidone 4768:Mirtazapine 4657:-Adrenergic 4636:Risperidone 4582:Mirtazapine 4532:Etoperidone 4499:Pheniramine 4484:Hydroxyzine 4305:Paraldehyde 4300:Loreclezole 4166:Afloqualone 4148:Piperidione 4138:Methyprylon 4067:Pazinaclone 4047:Eszopiclone 4009:Alphaxolone 4004:Alphadolone 3943:Monoureides 3885:Meprobamate 3822:Nitemazepam 3817:Nimetazepam 3762:Doxefazepam 3747:Cinolazepam 3719:Vinbarbital 3684:Proxibarbal 3669:Phenallymal 3604:Amobarbital 3556:Chloralodol 3456:from market 3323:Embutramide 3318:Anileridine 3290:Remimazolam 3227:Amobarbital 3204:Fospropofol 3167:Vinyl ether 3157:Sevoflurane 2715:"PENTOTHAL" 2654:(1): 7–12. 2076:Trickey D. 1915:: 207–211. 1616:10665/44771 1397:Mayo Clinic 1348:, a severe 1346:hypotension 1318:sulfonamide 1278:hypotension 1243:hypovolemia 1200:as it is a 1125:barbiturate 1119:Barbiturate 1086:truth serum 1080:Truth serum 1074:Truth serum 1025:Along with 919:sighthounds 841:barbiturate 824:truth serum 778:barbiturate 770:thiopentone 642: g·mol 579:100.000.694 346:Identifiers 301:Metabolites 237:Schedule IV 150:Barbiturate 80:Other names 71:Trade names 12135:Categories 12026:Citicoline 12006:Acetyl-coA 11990:Precursors 11966:Vanoxerine 11956:Tropeinium 11941:Toxiferine 11906:Reboxetine 11896:Radafaxine 11841:Neramexane 11831:Mivacurium 11826:Metocurine 11791:Malouetine 11756:Isoflurane 11711:Fazadinium 11706:Esketamine 11686:Doxacurium 11671:Dioscorine 11631:Desflurane 11596:Coclaurine 11528:Atracurium 11513:Amantadine 11503:Alcuronium 11256:Levamisole 11246:Ivermectin 11191:Dianicline 11151:Butinoline 11136:Anatoxin-a 11025:modulators 10948:AGN-241751 10920:Piretanide 10870:Furosemide 10855:Flupirtine 10832:Conantokin 10827:Caroverine 10822:Bumetanide 10755:Isoflurane 10725:Desflurane 10715:Chloroform 10654:Safaprodil 10649:Ro 25-6981 10590:Tiletamine 10575:Sabeluzole 10555:Remacemide 10500:Neramexane 10470:Methorphan 10455:Loperamide 10430:Lanicemine 10415:Indantadol 10380:Esketamine 10375:Ephenidine 10335:Dexoxadrol 10300:Arketamine 10285:Amantadine 10245:3-MeO-PCMo 10223:Putrescine 10166:MDL-105519 10141:Kynurenine 10121:Gavestinel 10036:SDZ-220581 9996:MDL-100453 9879:prasterone 9849:Spermidine 9822:Milacemide 9727:ACC (ACPC) 9613:Evans blue 9577:Topiramate 9567:Tezampanel 9497:Isoflurane 9374:Talampanel 9359:Perampanel 9354:Isoflurane 9339:GYKI-53655 9334:GYKI-52466 9329:Evans blue 9293:Zonampanel 9283:Topiramate 9273:Tezampanel 9248:Kynurenine 9208:Caroverine 9203:Becampanel 9153:Oxiracetam 9053:Aniracetam 8974:modulators 8829:Tilapertin 8784:LY-2365109 8779:Iclepertin 8774:GSK1018921 8659:zatosetron 8647:bemesetron 8619:Picrotoxin 8537:Imipramine 8507:bilobalide 8493:Furosemide 8483:nifedipine 8454:flurazepam 8442:clonazepam 8438:bromazepam 8409:Strychnine 8404:Sinomenine 8369:Quinolines 8359:Pitrazepin 8280:Dendrobine 8265:Colchicine 8184:isoflurane 8168:desflurane 8164:chloroform 8146:zatosetron 8130:bemesetron 8082:minaxolone 8070:alfaxolone 8056:Ivermectin 7993:Anandamide 7916:Milacemide 7906:-Threonine 7874:Ivermectin 7782:modulators 7668:Topiramate 7658:Terpenoids 7615:Propanidid 7605:Org 25,435 7533:Flupirtine 7528:Fluoxetine 7434:Chloralose 7405:ivermectin 7310:Norflurane 7275:Isoflurane 7220:Desflurane 7210:Chloroform 7170:Aliflurane 7103:Etaqualone 6931:SB-205,384 6861:CP-615,003 6856:CL-218,872 6810:Panadiplon 6800:Lorediplon 6729:Suproclone 6690:Zuranolone 6650:Renanolone 6635:Posovolone 6615:Minaxolone 6605:Ganaxolone 6544:Alfaxalone 6539:Alfadolone 6529:Acebrochol 6496:Bromisoval 6374:Metomidate 6361:Imidazoles 6321:Hispidulin 6273:Flavonoids 6233:Nisobamate 6223:Mebutamate 6193:Ethinamate 6188:Emylcamate 6155:Carbamates 6125:Tuclazepam 6100:Tetrazepam 6055:Reclazepam 6030:Premazepam 6010:Phenazepam 5990:Nordazepam 5985:Nitrazolam 5975:Nitrazepam 5955:Motrazepam 5910:Loprazolam 5900:Lofendazam 5885:Imidazenil 5845:Flutazolam 5840:Flurazepam 5810:Fletazepam 5765:Dimdazenil 5760:Diclazepam 5740:Cyprazepam 5730:Cloxazolam 5710:Clonazolam 5705:Clonazepam 5695:Climazolam 5655:Brotizolam 5650:Bromazolam 5645:Bromazepam 5640:Bretazenil 5635:Bentazepam 5625:Arfendazam 5620:Alprazolam 5615:Adinazolam 5587:Vinylbital 5567:Thiopental 5442:Methitural 5357:Buthalital 5352:Butalbital 5203:Isobutanol 5042:Metaxalone 5032:Mephenesin 4953:Pregabalin 4933:Gabapentin 4906:Suvorexant 4841:Niaprazine 4817:Quetiapine 4812:Olanzapine 4695:Tizanidine 4690:Romifidine 4680:Lofexidine 4670:Detomidine 4631:Quetiapine 4626:Olanzapine 4537:Nefazodone 4479:Doxylamine 4464:Captodiame 4275:Chloralose 4239:compounds 4181:Etaqualone 4077:Suproclone 4057:Lirequinil 4024:Minaxolone 4014:Eltanolone 3994:Acebrochol 3961:Bromisoval 3928:Metomidate 3915:Imidazoles 3875:Ethinamate 3870:Emylcamate 3857:Carbamates 3832:Nitrazolam 3827:Nitrazepam 3802:Loprazolam 3787:Flurazepam 3757:Clonazolam 3752:Climazolam 3742:Brotizolam 3724:Vinylbital 3709:Thiopental 3431:Propanidid 3405:Alfaxalone 3400:Alfadolone 3382:Tiletamine 3367:Esketamine 3349:Sufentanil 3333:Alfentanil 3252:Thiopental 3137:Isoflurane 3107:Desflurane 3097:Chloroform 2755:15 October 2575:2022-06-18 2550:2022-06-18 2525:2007-08-05 2356:: 1580–2. 2146:2009-12-08 2125:2008-07-18 2092:2020-10-13 1958:trauma.org 1952:Takeko T. 1806:2024-05-19 1781:2024-05-19 1714:23 January 1472:2023-08-16 1440:References 1299:somnolence 1267:anesthetic 1202:lipophilic 1192:Metabolism 1168:receptor. 1093:Psychiatry 1040:The Lancet 989:euthanasia 983:Euthanasia 888:zero-order 861:obstetrics 857:intubation 835:Anesthesia 766:thiopental 647:3D model ( 635:Molar mass 509:CHEBI:9561 469:49Y44QZL70 440:ChemSpider 372:CAS Number 355:IUPAC name 289:Metabolism 145:Drug class 12196:Sedatives 12166:Hypnotics 11866:Pentamine 11861:Pempidine 11811:Methadone 11806:Memantine 11726:Halothane 11716:Gallamine 11696:Enflurane 11651:Diadonium 11566:Bupropion 11351:SIB-1553A 11346:SIB-1508Y 11336:SB-206553 11161:Carbachol 11141:AR-R17779 11131:Anatabine 11126:Anabasine 11091:A-867,744 11086:A-582,941 11081:A-366,833 10962:See also: 10942:Unsorted: 10885:MDL-27266 10865:FR-115427 10860:FPL-12495 10817:ARR-15896 10745:Halothane 10735:Enflurane 10693:Magnesium 10644:Ro 8-4304 10619:Eliprodil 10530:PD-137889 10490:Morphanol 10465:Methadone 10460:Memantine 10410:Ibogamine 10385:Etoxadrol 10315:ARL-16247 10305:ARL-12495 10290:Aptiganel 10255:4-MeO-PCP 10250:3-MeO-PCP 10240:3-MeO-PCE 10203:Co 101676 10176:MRZ 2/576 10126:GV-196771 10116:Felbamate 10093:CGP-39653 10073:ACEA-1328 10068:ACEA-1011 10011:NPC-17742 10006:NPC-12626 9991:LY-274614 9986:LY-235959 9981:LY-233053 9966:CGS-19755 9961:CGP-40116 9956:CGP-39653 9951:CGP-39551 9946:CGP-37849 9936:AP5 (APV) 9837:Sarcosine 9713:β-Fluoro- 9662:Glutamate 9657:Aspartate 9646:Agonists: 9603:Enflurane 9547:LY-382884 9507:ACEA-1011 9492:Halothane 9487:Enflurane 9482:Diazoxide 9455:LY-339434 9440:Glutamate 9404:Agonists: 9349:Irampanel 9344:Halothane 9319:Enflurane 9193:ACEA-1011 9168:Piracetam 9148:ORG-26576 9143:Nooglutyl 9133:LY-503430 9128:LY-451646 9123:LY-404187 9118:LY-395153 9113:LY-392098 9098:Diazoxide 9026:Glutamate 8995:Agonists: 8877:ORG-25543 8857:Amoxapine 8814:Sarcosine 8794:ORG-24598 8759:CP-802079 8665:Verapamil 8651:LY-278584 8643:Tropeines 8609:pethidine 8605:oripavine 8498:Genistein 8429:Amiloride 8309:Gelsemine 8285:Diaboline 8270:Colubrine 8180:halothane 8176:enflurane 8152:Volatiles 8138:LY-278584 8122:Tropeines 8117:Triclofos 8107:Tamoxifen 8086:ORG-20599 8032:Etomidate 7955:brometone 7936:Sarcosine 7911:MDL-27531 7823:β-Alanine 7820:Agonists: 7727:See also: 7689:valerenol 7610:Phenytoin 7590:Monastrol 7548:Lanthanum 7543:KRM-II-81 7506:Fenamates 7501:Etifoxine 7496:Etazepine 7491:Efavirenz 7449:Darigabat 7345:Teflurane 7330:Roflurane 7325:Propylene 7270:Halothane 7255:Fluroxene 7240:Enflurane 7143:Volatiles 7060:Etazolate 6971:Viqualine 6926:RWJ-51204 6891:L-838,417 6881:Imepitoin 6851:CGS-20625 6846:CGS-13767 6831:Adipiplon 6805:Ocinaplon 6767:Saripidem 6762:Necopidem 6739:Zopiclone 6734:Suriclone 6719:Pagoclone 6625:ORG-21465 6620:ORG-20599 6511:Ectylurea 6501:Carbromal 6379:Propoxate 6369:Etomidate 6296:Baicalein 6253:Styramate 6248:Procymate 6218:Lorbamate 6203:Felbamate 6173:Clocental 6145:Zomebazam 6140:Zolazepam 6135:Zapizolam 6130:Uldazepam 6110:Triazolam 6095:Temazepam 6090:Sulazepam 6080:Ro48-8684 6075:Ro48-6791 6070:Ripazepam 6040:Pyrazolam 6015:Pinazepam 5965:Nifoxipam 5950:Midazolam 5945:Mexazolam 5930:Medazepam 5915:Lorazepam 5895:Ketazolam 5890:Irazepine 5880:Iclazepam 5870:Halazepam 5865:Gidazepam 5860:Fosazepam 5780:Estazolam 5775:Elfazepam 5750:Demoxepam 5680:Cinazepam 5660:Camazepam 5630:Avizafone 5552:Thiamylal 5487:Primidone 5417:Heptabarb 5407:Eterobarb 5372:Carbubarb 5269:Triclofos 5168:Brometone 5079:Trazodone 5020:-related 4873:Ramelteon 4868:Melatonin 4855:Melatonin 4763:Mianserin 4730:Trazodone 4665:Clonidine 4577:Mianserin 4542:Trazodone 4494:Perlapine 4337:Triclofos 4290:Gaboxadol 4097:Zopiclone 4082:Suriclone 4072:Saripidem 4062:Necopidem 3976:Ectylurea 3971:Carbromal 3933:Propoxate 3923:Etomidate 3900:Procymate 3847:Triazolam 3842:Temazepam 3812:Midazolam 3767:Estazolam 3704:Thiamylal 3639:Heptabarb 3518:sedatives 3514:Hypnotics 3466:Phase III 3454:Withdrawn 3426:Etomidate 3313:Oxycodone 3285:Lorazepam 3275:Midazolam 3247:Thiamylal 3182:Injection 3132:Halothane 3127:Fluroxene 3117:Enflurane 2600:March 10, 2272:18 August 2247:18 August 2238:bbc.co.uk 2217:18 August 2207:bbc.co.uk 2115:The Hague 1968:18 August 1888:13 August 1795:Orwig J. 1757:897466425 1635:0512-3054 1607:children) 1354:porphyria 1344:, severe 1340:, severe 1245:, burns, 1235:clonidine 1227:sedatives 1158:GABAergic 1107:Holocaust 1045:autopsies 1043:reported 926:; severe 904:half-life 670:Chirality 529:ChEMBL738 326:half-life 133:Routes of 107:Pregnancy 99:Monograph 93:Drugs.com 12125:Medicine 12078:See also 12020:lecithin 11996:prodrugs 11946:Tramadol 11796:ME-18-MC 11761:Ketamine 11751:Ibogaine 11571:BW284C51 11326:RJR-2429 11316:Pyrantel 11276:Nicotine 11271:Morantel 11261:Lobeline 11226:EVP-6124 11221:EVP-4473 11176:Cytisine 11171:Cotinine 11076:A-84,543 11047:Agonists 10890:Metaphit 10800:Urethane 10688:Hydrogen 10685:Cations: 10595:Tramadol 10420:Ketamine 10405:Ibogaine 10320:Budipine 10235:3-HO-PCP 10161:LU-73068 10151:L-701324 10146:L-689560 10053:5,7-DCKA 10041:Selfotel 9923:SAGE-718 9918:SAGE-301 9913:SAGE-201 9854:Spermine 9844:Neomycin 9809:-Alanine 9801:L-687414 9760:-Alanine 9717:-alanine 9706:Theanine 9572:Theanine 9470:SYM-2081 9278:Theanine 8898:See also 8852:ALX-1393 8715:blockers 8696:instead. 8638:Riluzole 8623:picrotin 8613:thebaine 8601:morphine 8470:Daidzein 8460:Corymine 8446:diazepam 8381:5,7-CIQA 8314:iso-THAZ 8260:Caffeine 8126:atropine 8102:Propofol 8061:Ketamine 7951:Alcohols 7926:Propofol 7890:-Proline 7882:-Alanine 7846:-Alanine 7790:Receptor 7715:TCS-1205 7710:TCS-1105 7700:α-Pinene 7673:Valerian 7648:tetronal 7625:Safranal 7574:obovatol 7570:magnolol 7566:honokiol 7396:Alogabat 7391:AA-29504 7340:Synthane 7300:Nitrogen 7280:Kerosine 7260:Gasoline 7250:Ethylene 7190:Centalun 7185:Butylene 6999:Propofol 6961:U-89843A 6941:TGSC01AA 6911:NS-11394 6876:GBLD-345 6841:CGS-9896 6836:CGS-8216 6820:Zaleplon 6815:Taniplon 6795:Indiplon 6790:Fasiplon 6785:Divaplon 6772:Zolpidem 6675:SAGE-872 6670:SAGE-689 6665:SAGE-516 6660:SAGE-324 6655:SAGE-105 6563:Certain 6506:Capuride 6468:Yangonin 6345:baicalin 6341:Skullcap 6331:Luteolin 6306:Catechin 6301:Baicalin 6291:Apigenin 6263:Tybamate 6050:Quazepam 6045:QH-II-66 6025:Prazepam 6005:Oxazolam 6000:Oxazepam 5800:Etizolam 5755:Diazepam 5735:CP-1414S 5700:Clobazam 5690:Clazolam 5577:Valofane 5532:Talbutal 5522:Sigmodal 5427:Hexethal 5322:Barbital 5302:Alphenal 5292:(-)-DMBB 5238:Propanol 5228:Pentanol 5218:Methanol 5160:Alcohols 5063:morphine 5054:Midaflur 4974:Cannabis 4948:Phenibut 4700:Xylazine 4429:Phenibut 4399:Baclofen 4325:Tetronal 4260:Centalun 4115:Propofol 4092:Zolpidem 4087:Zaleplon 4052:Indiplon 3966:Capuride 3905:Tybamate 3837:Quazepam 3699:Talbutal 3614:Barbital 3543:Alcohols 3372:Ketamine 3328:Fentanyl 3308:Morphine 3280:Diazepam 3209:Propofol 3199:Ciprofol 3122:Ethylene 2847:16953192 2798:10928003 2633:13243246 2570:NBC News 2545:Guardian 2497:10049127 2466:15644873 2419:: 18–20. 2242:BBC News 2211:BBC News 2167:CBS News 2063:23235573 2006:29058090 1939:28955958 1856:27366476 1775:BBC News 1682:(2021). 1651:(2019). 1604:(2012). 1576:(2009). 1516:24285007 1466:Archived 1428:See also 1338:myxedema 1310:molecule 1247:azotemia 1229:such as 1137:receptor 924:vesicant 849:propofol 801:propofol 774:Trapanal 736:(verify) 420:DrugBank 308:, others 225:Class B1 157:ATC code 109:category 12016:Choline 11576:BW-A444 11554:(e.g., 11547:BNC-210 11535:(e.g., 11498:ABT-126 11482:(e.g., 11441:XY-4083 11406:TC-6683 11401:TC-5619 11396:TC-5214 11391:TC-2216 11386:TC-1827 11381:TC-1734 11376:TC-1698 11286:NS-1738 11280:tobacco 11166:Choline 11111:ABT-894 11106:ABT-560 11101:ABT-418 11096:ABT-202 10934:saffron 10780:Toluene 10770:Octanol 10750:Hexanol 10705:Benzene 10681:TCN-213 10676:TCN-201 10671:MPX-007 10666:MPX-004 10260:8A-PDHQ 10198:Arcaine 10191:ZD-9379 9888:sulfate 9817:-Serine 9791:Glycine 9776:-Serine 9691:Proline 9618:NS-3763 9591:(e.g., 9582:UBP-302 9460:Proline 9302:(e.g., 9178:S-18986 9108:IDRA-21 9093:CX-1942 9088:CX-1739 9036:Proline 8882:VVZ-368 8749:ASP2535 8645:(e.g., 8621:(i.e., 8581:codeine 8579:(e.g., 8577:Opioids 8549:(e.g., 8513:(e.g., 8477:(e.g., 8436:(e.g., 8399:RU-5135 8371:(e.g., 8292:(e.g., 8250:Brucine 8196:toluene 8158:(e.g., 8134:cocaine 8124:(e.g., 8068:(e.g., 8043:(e.g., 8037:Ginseng 8024:(e.g., 8017:D12-116 8000:(e.g., 7953:(e.g., 7941:Taurine 7898:-Serine 7864:Glycine 7854:-Serine 7838:Caesium 7796:ligands 7662:borneol 7660:(e.g., 7652:trional 7642:(e.g., 7560:(e.g., 7558:Lignans 7508:(e.g., 7466:(e.g., 7411:Bromide 7403:(e.g., 7386:α-EMTBL 7350:Toluene 7320:Propane 7195:Chloral 7175:Benzene 7155:Acetone 6986:Phenols 6976:Y-23684 6966:U-90042 6951:TPA-023 6936:SX-3228 6921:ROD-188 6906:NS-2710 6901:NS-2664 6886:JM-1232 6871:ELB-139 6866:CTP-354 6752:Alpidem 6351:Wogonin 6326:Linarin 5805:FG-8205 5512:Reposal 5213:Menthol 5173:Butanol 5061:(e.g., 5059:Opioids 5008:Evoxine 4745:Doxepin 4559:Doxepin 4434:Tolibut 4330:Trional 4237:Bromide 4107:Phenols 3689:Reposal 3300:Opioids 3191:Phenols 3033:Archive 3006:7547061 2923:5175948 2838:1978439 2729:18 June 2701:2310019 2660:3093002 2457:1575970 2370:6108082 2054:7061245 2014:3013248 1930:5613958 1847:4917150 1560:7235275 1508:8751034 1401:Hospira 1383:History 1257:, etc. 1178:Hospira 1099:phobias 809:Hospira 596:Formula 449:2272257 429:DB00599 409:3000714 395:PubChem 381:71-73-8 249:Class B 235:: 177: ( 175:N05CA19 173:) 167: ( 165:N01AF03 122: D 12111:Portal 11606:Curare 11523:AQW051 11470:18-MAC 11426:UB-165 11236:GTS-21 11066:5-HIAA 11034:nAChRs 10810:Xylene 10710:Butane 10083:AV-101 9796:HA-966 9083:CX-717 9073:CX-614 9068:CX-546 9063:CX-516 8503:Ginkgo 8393:7-TFQA 8240:αEMBTL 7833:β-AIBA 7595:Niacin 7180:Butane 7133:SL-164 7004:Thymol 6946:TP-003 6827:Others 6630:P1-185 6590:5β-DHP 6585:5α-DHP 6580:3α-DHP 6428:Kavain 6336:Rc-OMe 4962:Others 4888:Orexin 4834:Others 4824:, etc. 4801:, etc. 4770:, etc. 4752:, etc. 4638:, etc. 4615:, etc. 4584:, etc. 4566:, etc. 4220:Others 4211:SL-164 3449:WHO-EM 3419:Others 3004:  2954:  2921:  2845:  2835:  2796:  2719:RXList 2699:  2658:  2631:  2495:  2464:  2454:  2368:  2352:(12). 2327:  2267:gov.uk 2061:  2051:  2012:  2004:  1937:  1927:  1879:  1854:  1844:  1755:  1745:  1633:  1623:  1558:  1514:  1506:  1454:Anvisa 1371:or by 1314:sulfur 1303:nausea 1301:, and 1286:airway 1284:, and 1221:Dosage 1147:, the 881:uterus 785:analog 685:SMILES 640:264.32 520:ChEMBL 489:D00714 259: 247: 223: 210: 11994:(and 11976:Xenon 11475:18-MC 11454:(and 11050:(and 10805:Xenon 10265:18-MC 10230:2-MDP 10058:7-CKA 10021:PEAQX 9747:B6B21 9737:AK-51 9671:-HCA) 9634:NMDAR 9557:NS102 9288:YM90K 8983:AMPAR 8867:NAGly 8840:GlyT2 8739:ACPPB 8727:GlyT1 8681:NMDAR 8419:Tutin 8389:7-TFQ 8385:7-CIQ 8210:Xenon 8156:gases 7454:DEABL 7147:gases 6956:TP-13 6685:THDOC 6575:DHDOC 5084:UMB68 4404:GABOB 3172:Xenon 2965:(PDF) 2723:WebMD 2415:(1). 2010:S2CID 1512:S2CID 1282:apnea 1270:drugs 772:, or 705:InChI 649:JSmol 500:ChEBI 294:Liver 11656:DHβE 11457:NAMs 11053:PAMs 10900:MPEP 10840:-αAA 10698:Zinc 10525:PCPr 10495:NEFA 10181:PNQX 10111:DNQX 10098:CNQX 10031:PPDA 10016:PBPD 9886:DHEA 9871:DHEA 9781:DHPG 9732:ACPD 9722:ACBD 9686:NMDA 9652:AMAA 9552:NBQX 9527:GAMS 9522:DNQX 9512:CNQX 9430:ATPA 9425:AMPA 9263:PNQX 9258:NBQX 9233:GAMS 9223:DNQX 9213:CNQX 9198:ATPO 9158:PEPA 9016:BOAA 9011:AMPA 8917:GABA 8694:here 8692:See 8670:Zinc 8633:PMBA 8625:and 8542:NBQX 8294:2-AG 8215:Zinc 7968:tert 7859:GABA 7808:GlyR 6757:DS-1 6389:Kava 6316:EGCG 5252:tert 5244:tert 5147:GABA 4924:VDCC 4710:5-HT 4373:GABA 3551:2M2B 3531:GABA 3522:N05C 3080:N01A 3002:PMID 2952:ISBN 2919:PMID 2843:PMID 2794:PMID 2757:2010 2731:2023 2697:PMID 2656:PMID 2629:PMID 2602:2021 2493:PMID 2462:PMID 2389:TIME 2366:PMID 2325:ISBN 2274:2016 2249:2016 2219:2016 2059:PMID 2037:2012 2002:PMID 1970:2016 1935:PMID 1890:2016 1877:ISBN 1852:PMID 1753:OCLC 1743:ISBN 1716:2014 1631:ISSN 1621:ISBN 1556:PMID 1504:PMID 1133:GABA 1029:and 855:and 830:Uses 480:KEGG 460:UNII 273:data 89:AHFS 10063:ACC 9971:CPP 9941:AP7 9752:CCG 9392:KAR 7486:DS2 6595:DHT 6311:EGC 4424:GVL 4419:GBL 4409:GHB 3035:). 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1562:. 1548:: 1518:. 1498:: 1475:. 1166:A 1162:A 1153:A 1135:A 952:2 651:) 628:S 625:2 622:O 616:2 613:N 607:H 601:C 547:) 543:( 257:: 245:: 221:: 208:: 183:) 120:: 91:/ 36:. 29:.

Index

pentobarbital
phenobarbital
Sound of White Noise


Trade names
AHFS
Drugs.com
Monograph
Pregnancy
category

Routes of
administration

Drug class
Barbiturate
ATC code
N01AF03
WHO
N05CA19
WHO
Legal status
S4
Class B1
Schedule IV
Class B
Schedule III
Pharmacokinetic
Protein binding
Metabolism
Liver
Metabolites
Pentobarbital

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