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Soft tissue

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202: 31: 2712: 253:. In order to describe the mechanical response of soft tissues, several methods have been used. These methods include: hyperelastic macroscopic models based on strain energy, mathematical fits where nonlinear constitutive equations are used, and structurally based models where the response of a linear elastic material is modified by its geometric characteristics. 198:
properties may be useful for forensics investigation when contusions were induced. When a solid object impacts a human soft tissue, the energy of the impact will be absorbed by the tissues to reduce the effect of the impact or the pain level; subjects with more soft tissue thickness tended to absorb the impacts with less aversion.
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Musculoskeletal specialists, manual therapists, neuromuscular physiologists and neurologists specialize in treating injuries and ailments in the soft tissue areas of the body. These specialized clinicians often develop innovative ways to manipulate the soft tissue to speed natural healing and relieve
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Despite the independence of strain rate, preconditioned soft tissues still present hysteresis, so the mechanical response can be modeled as hyperelastic with different material constants at loading and unloading. By this method the elasticity theory is used to model an inelastic material. Fung has
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The collagen fibers are approximately 1-2 μm thick. Thus, the resolution of the imaging technique needs to be approximately 0.5 μm. Some techniques allow the direct acquisition of volume data while other need the slicing of the specimen. In both cases, the volume that is extracted must be able to
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Human soft tissue is highly deformable, and its mechanical properties vary significantly from one person to another. Impact testing results showed that the stiffness and the damping resistance of a test subject's tissue are correlated with the mass, velocity, and size of the striking object. Such
1377: 357: 182:. The collagen fibers are comparatively inextensible and are usually loose (wavy, crimped). With increasing tissue deformation the collagen is gradually stretched in the direction of deformation. When taut, these fibers produce a strong growth in tissue stiffness. The 1556:
is proportional to these stimuli. Diseases, injuries and changes in the level of mechanical load may induce remodeling. An example of this phenomenon is the thickening of farmer's hands. The remodeling of connective tissues is well known in bones by the
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are some of the most chronically painful and difficult conditions to treat because it is very difficult to see what is going on under the skin with the soft connective tissues, fascia, joints, muscles and tendons.
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is a stiffening parameter, associated with limiting chain extensibility. This constitutive model cannot be stretched in uni-axial tension beyond a maximal stretch
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Elbischger PJ, Bischof H, Holzapfel GA, Regitnig P (2005). "Computer vision analysis of collagen fiber bundles in the adventitia of human blood vessels".
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The Fung-model, simplified with isotropic hypothesis (same mechanical properties in all directions). This written in respect of the principal stretches (
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causes shrinkage, altering the structure of the original tissue. Some typical values of contraction for different fixation are: formalin (5% - 10%),
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Alkhaledi K, Cochran D, Riley M, Stentz T, Bashford G, Meyer G (August 2011). "The psycophysical effects of physical impact to human soft tissue".
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Soft tissues have the potential to grow and remodel reacting to chemical and mechanical long term changes. The rate the fibroblasts produce
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Soft tissues have the potential to undergo large deformations and still return to the initial configuration when unloaded, i.e. they are
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to a load pattern. After some cycles of loading and unloading the material, the mechanical response becomes independent of strain rate.
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are the most common cell responsible for the production of soft tissues' fibers and ground substance. Variations of fibroblasts, like
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Even though soft tissues have viscoelastic properties, i.e. stress as function of strain rate, it can be approximated by a
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and is rapidly expanding as technology continues to improve the ability of these specialists to identify problem areas.
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does the role of collagen. In soft tissues, the collagen limits the deformation and protects the tissues from injury.
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There are certain issues that have to be kept in mind when choosing an imaging technique for visualizing soft tissue
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Humphrey JD (2008). "Vascular adaptation and mechanical homeostasis at tissue, cellular, and sub-cellular levels".
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Rozman P, Bolta Z (December 2007). "Use of platelet growth factors in treating wounds and soft-tissue injuries".
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must be aware of this fact to avoid mistakes when analyzing excised tissues. This retraction usually causes a
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the mysterious pain that often accompanies soft tissue injuries. This area of expertise has become known as
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Growth and remodeling have a major role in the cause of some common soft tissue diseases, like arterial
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On the other hand, the linear term is negligible when the analysis rely only on big strains.
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is the science that study the relation between stress and growth at cellular level.
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easier, especially when color information is available. In addition, the need for
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It is sometimes defined by what it is not – such as "nonepithelial, extraskeletal
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per volume unit, which is the mechanical strain energy for a given temperature.
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Proceedings of the 29th Annual European Conference on Cognitive Ergonomics
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A promising new method of treating wounds and soft tissue injuries is via
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Humphrey JD (2003). "Continuum biomechanics of soft biological tissues".
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For small strains, the exponential term is very small, thus negligible.
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must also be addressed. It has been shown that soft tissue fixation in
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There is a close overlap between the term "soft tissue disorder" and
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and surrounds or supports internal organs and bones, and includes
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follow the fiber bundles across the volume. High contrast makes
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Establishing an easy and reproducible setup for tissue analysis.
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Having an optimal resolution for the components of interest;
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Gent AN (1996). "A new constitutive relation for rubber".
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Journal of the Mechanical Behavior of Biomedical Materials
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Acta Dermatovenerologica Alpina, Pannonica, et Adriatica
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Saini K, Cho S, Dooling LJ, Discher DE (January 2020).
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Tissue in the body that is not hardened by ossification
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Biomechanics: Mechanical Properties of Living Tissues
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to point out that the material is not truly elastic.
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In physiological state soft tissues usually present
190:, whose rubber band does the role of elastin as the 1408:is the shear modulus for infinitesimal strains and 1536: 1460: 1433: 1400: 1371: 1206: 1096: 1003: 796: 757: 737: 717: 681: 645: 609: 483: 351: 3430:Shoulder injury related to vaccine administration 2688:Meleger AL (June 2022). Isaac Z, Case SM (eds.). 2325: 3619: 2439:Topol H, Demirkoparan H, Pence TJ (2021-09-01). 2126:Current diagnosis & treatment in orthopedics 2117: 2530: 2326:Sherman VR, Yang W, Meyers MA (December 2015). 2536: 1997:are medical conditions affecting soft tissue. 3161: 2738: 2690:"Overview of soft tissue rheumatic disorders" 1621:Having the option of volume data acquisition; 165: 2583:Studies in Health Technology and Informatics 2543:Proceedings of the Royal Society of London A 2253:Proceedings of the Royal Society of London A 1615:Achieving high contrast of those components; 2660: 2149:Junqueira LC, Carneiro J, Gratzl M (2005). 772: 3168: 3154: 2745: 2731: 2305:. New York: Springer-Verlag. p. 568. 2246: 2244: 1019:Simplification for small and big stretches 410:for preconditioned soft tissues which is 3175: 2637: 2562: 2487: 2415: 2343: 2191: 138:The characteristic substances inside the 3216:Stenosing tenosynovitis (Trigger finger) 2608:Georgakoudi I, Rice WL, Hronik-Tupaj M, 2493: 2250: 2142: 1989: 1547: 1217: 398: 379:that may be released when the tissue is 200: 29: 2687: 2241: 2174:Amar M, Alkhaledi K, Cochran D (2014). 2123: 14: 3620: 2549:(2118). The Royal Society: 1551–1597. 2296: 2294: 2292: 2290: 2076: 2074: 2034:that can develop in the soft tissues. 3149: 2752: 2726: 2576: 2574: 2402:. Matrix Biomechanics. 85–86: 34–46. 1599: 1004:{\displaystyle W={\frac {1}{2}}\left} 484:{\displaystyle W={\frac {1}{2}}\left} 178:to the tissue and stores most of the 162:, may also produce these substances. 2539:"Constitutive modelling of arteries" 2366: 2300: 1683:Multi-Photon Excitation Fluorescence 1659:visualization and their properties. 213:(λ) of a preconditioned soft tissue. 3420:Adhesive capsulitis of the shoulder 2618:Tissue Engineering. Part B, Reviews 2328:"The materials science of collagen" 2287: 2071: 256: 24: 2571: 370: 25: 3654: 3042:Dense irregular connective tissue 2704: 2710: 2496:Cell Biochemistry and Biophysics 1468:, which is the positive root of 1015:where a, b and c are constants. 342: 334: 326: 307: 296: 288: 280: 3059:Dense regular connective tissue 2654: 2601: 2537:Holzapfel GA, Ogden RW (2010). 2432: 2387: 2360: 2180:Journal of Engineering Research 1618:Keeping the artifact count low; 555: 324: 320: 2319: 2200: 2167: 2095: 2015:platelet-derived growth factor 980: 920: 898: 838: 346: 338: 321: 317: 292: 133: 13: 1: 3425:Shoulder impingement syndrome 3268:Tenosynovial giant cell tumor 2502:(2). Springer-Verlag: 53–78. 2064: 1588:in response to the growth of 3247:Synovial osteochondromatosis 2408:10.1016/j.matbio.2019.06.001 1698:Optical coherence tomography 1624:Keeping the data volume low; 797:{\displaystyle \lambda _{i}} 229:. The soft tissues are also 7: 2345:10.1016/j.jmbbm.2015.05.023 2037: 186:behavior is analogous to a 43:Hematoxylin and eosin stain 10: 3659: 1690:Second Harmonic Generation 1434:{\displaystyle J_{m}>0} 1221: 166:Mechanical characteristics 3574: 3537: 3530: 3498: 3453: 3408: 3389: 3368: 3359: 3278: 3192: 3183: 3111: 3088: 3032: 2997: 2988: 2981: 2899: 2881: 2870: 2843: 2802: 2793: 2786: 2760: 2630:10.1089/ten.teb.2008.0248 2508:10.1007/s12013-007-9002-3 2445:Applied Mechanics Reviews 2193:10.7603/s40632-014-0026-8 2111:National Cancer Institute 1401:{\displaystyle \mu >0} 1224:Gent (hyperelastic model) 3465:Iliotibial band syndrome 1655:Imaging methods used in 773:Isotropic simplification 718:{\displaystyle b_{ijkl}} 682:{\displaystyle a_{ijkl}} 95:in the body that is not 3598:Aggressive fibromatosis 3588:Dupuytren's contracture 2217:10.1145/2074712.2074774 142:of soft tissue are the 3262:villonodular synovitis 2564:10.1098/rspa.2010.0058 2273:10.1098/rspa.2002.1060 1538: 1462: 1435: 1402: 1373: 1208: 1098: 1005: 798: 767:strain energy function 759: 739: 719: 683: 647: 646:{\displaystyle E_{ij}} 622:Green-Lagrange strains 611: 485: 353: 219:hyperelastic materials 214: 91:. Soft tissue is 46: 3177:Soft tissue disorders 1995:Soft tissue disorders 1990:Clinical significance 1548:Remodeling and growth 1539: 1463: 1461:{\displaystyle J_{m}} 1436: 1403: 1374: 1222:Further information: 1218:Gent-elastic material 1209: 1099: 1006: 799: 760: 740: 720: 684: 648: 612: 486: 408:constitutive equation 399:Fung-elastic material 363:called this model as 354: 204: 33: 3593:Plantar fibromatosis 3221:De Quervain syndrome 2719:at Wikimedia Commons 2369:Rubber Chem. Technol 2211:. pp. 269–270. 2028:Soft tissue sarcomas 1999:Soft tissue injuries 1814:Up to 2–3 mm 1606:extracellular matrix 1580:and any soft tissue 1475: 1445: 1412: 1386: 1232: 1114: 1030: 811: 781: 749: 745:material constants. 729: 693: 657: 627: 501: 417: 276: 140:extracellular matrix 99:by the processes of 3643:Continuum mechanics 3475:Achilles tendinitis 3470:Patellar tendinitis 3241:osteochondromatosis 3228:Transient synovitis 3211:Calcific tendinitis 2555:2010RSPSA.466.1551H 2457:2021ApMRv..73e0802T 2265:2003RSPSA.459....3H 2124:Skinner HB (2006). 2008:soft tissue therapy 1746:Lateral: 1-15 μm 1719:Axial: 0.25-0.5 μm 1492: 1340: 1322: 1304: 973: 955: 937: 891: 873: 855: 620:quadratic forms of 223:stress-strain curve 124:reticuloendothelial 3376:Ligamentous laxity 2030:are many types of 1669:Transmission Light 1600:Imaging techniques 1534: 1478: 1458: 1431: 1398: 1369: 1326: 1308: 1290: 1204: 1094: 1001: 959: 941: 923: 877: 859: 841: 794: 755: 735: 715: 679: 643: 607: 481: 349: 215: 174:, elastin confers 89:synovial membranes 47: 3638:Tissues (biology) 3615: 3614: 3611: 3610: 3526: 3525: 3522: 3521: 3435:Rotator cuff tear 3355: 3354: 3347:Calcific bursitis 3143: 3142: 3139: 3138: 3084: 3083: 2977: 2976: 2973: 2972: 2866: 2865: 2754:Connective tissue 2715:Media related to 2612:(December 2008). 2465:10.1115/1.4052752 2381:10.5254/1.3538357 1987: 1986: 1968:Moderate to high 1358: 1264: 1131: 1047: 828: 758:{\displaystyle W} 738:{\displaystyle c} 434: 314: 207:lagrangian stress 122:exclusive of the 16:(Redirected from 3650: 3535: 3534: 3503: 3458: 3413: 3406: 3405: 3366: 3365: 3190: 3189: 3170: 3163: 3156: 3147: 3146: 2995: 2994: 2986: 2985: 2914:Reticular fibers 2883:Ground substance 2879: 2878: 2800: 2799: 2791: 2790: 2747: 2740: 2733: 2724: 2723: 2714: 2698: 2697: 2685: 2679: 2678: 2658: 2652: 2651: 2641: 2605: 2599: 2598: 2578: 2569: 2568: 2566: 2534: 2528: 2527: 2491: 2485: 2484: 2436: 2430: 2429: 2419: 2391: 2385: 2384: 2364: 2358: 2357: 2347: 2323: 2317: 2316: 2301:Fung YC (1993). 2298: 2285: 2284: 2248: 2239: 2238: 2204: 2198: 2197: 2195: 2171: 2165: 2164: 2146: 2140: 2139: 2121: 2115: 2114: 2107:NCI Dictionaries 2099: 2093: 2092: 2090: 2088: 2078: 1822:Image stack cost 1662: 1661: 1592:detected by the 1543: 1541: 1540: 1535: 1521: 1520: 1508: 1507: 1491: 1486: 1467: 1465: 1464: 1459: 1457: 1456: 1440: 1438: 1437: 1432: 1424: 1423: 1407: 1405: 1404: 1399: 1378: 1376: 1375: 1370: 1368: 1364: 1363: 1359: 1357: 1356: 1347: 1339: 1334: 1321: 1316: 1303: 1298: 1288: 1265: 1260: 1259: 1258: 1245: 1213: 1211: 1210: 1205: 1203: 1199: 1192: 1191: 1190: 1189: 1177: 1176: 1164: 1163: 1132: 1124: 1103: 1101: 1100: 1095: 1093: 1092: 1080: 1079: 1067: 1066: 1048: 1040: 1010: 1008: 1007: 1002: 1000: 996: 995: 991: 984: 983: 972: 967: 954: 949: 936: 931: 890: 885: 872: 867: 854: 849: 829: 821: 803: 801: 800: 795: 793: 792: 764: 762: 761: 756: 744: 742: 741: 736: 724: 722: 721: 716: 714: 713: 688: 686: 685: 680: 678: 677: 652: 650: 649: 644: 642: 641: 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3584: 3582: 3572: 3571: 3569: 3568: 3563: 3558: 3553: 3543: 3541: 3532: 3528: 3527: 3524: 3523: 3520: 3519: 3517: 3516: 3506: 3504: 3501:other/general: 3496: 3495: 3493: 3492: 3487: 3482: 3480:Calcaneal spur 3477: 3472: 3467: 3461: 3459: 3451: 3450: 3448: 3447: 3442: 3440:Golfer's elbow 3437: 3432: 3427: 3422: 3416: 3414: 3403: 3387: 3386: 3384: 3383: 3378: 3372: 3370: 3363: 3357: 3356: 3353: 3352: 3350: 3349: 3344: 3343: 3342: 3332: 3331: 3330: 3325: 3320: 3318:Retrocalcaneal 3315: 3310: 3305: 3300: 3295: 3284: 3282: 3276: 3275: 3273: 3272: 3271: 3270: 3257: 3256: 3254:Plica syndrome 3251: 3250: 3249: 3236: 3235: 3230: 3225: 3224: 3223: 3218: 3213: 3198: 3196: 3187: 3181: 3180: 3173: 3172: 3165: 3158: 3150: 3141: 3140: 3137: 3136: 3134: 3133: 3128: 3123: 3117: 3115: 3109: 3108: 3106: 3105: 3100: 3094: 3092: 3086: 3085: 3082: 3081: 3079: 3078: 3077: 3076: 3071: 3066: 3056: 3055: 3054: 3049: 3038: 3036: 3030: 3029: 3027: 3026: 3025: 3024: 3019: 3009: 3003: 3001: 2992: 2983: 2979: 2978: 2975: 2974: 2971: 2970: 2968: 2967: 2966: 2965: 2960: 2955: 2954: 2953: 2948: 2938: 2933: 2926:Elastic fibers 2923: 2922: 2921: 2911: 2905: 2903: 2897: 2896: 2894: 2893: 2887: 2885: 2876: 2872:Extracellular 2868: 2867: 2864: 2863: 2861: 2860: 2855: 2849: 2847: 2841: 2840: 2838: 2837: 2832: 2827: 2822: 2820:Reticular cell 2817: 2812: 2806: 2804: 2797: 2788: 2784: 2783: 2781: 2780: 2775: 2770: 2764: 2762: 2758: 2757: 2750: 2749: 2742: 2735: 2727: 2721: 2720: 2706: 2705:External links 2703: 2700: 2699: 2680: 2669:(4): 156–165. 2653: 2624:(4): 321–340. 2600: 2570: 2529: 2486: 2431: 2400:Matrix Biology 2386: 2359: 2318: 2311: 2286: 2259:(2029): 3–46. 2240: 2225: 2199: 2166: 2159: 2141: 2134: 2116: 2094: 2069: 2068: 2066: 2063: 2062: 2061: 2056: 2051: 2046: 2039: 2036: 1991: 1988: 1985: 1984: 1979: 1974: 1969: 1966: 1961: 1953: 1952: 1947: 1942: 1937: 1932: 1927: 1919: 1918: 1913: 1908: 1903: 1898: 1893: 1885: 1884: 1879: 1874: 1869: 1864: 1859: 1851: 1850: 1845: 1840: 1835: 1830: 1825: 1817: 1816: 1811: 1806: 1801: 1796: 1791: 1783: 1782: 1777: 1772: 1767: 1762: 1757: 1749: 1748: 1740: 1738:Lateral: 1 μm 1735:Axial: 0.5 μm 1732: 1730:Lateral: 1 μm 1727:Axial: 0.5 μm 1724: 1722:Lateral: 1 μm 1716: 1711: 1703: 1702: 1693: 1686: 1679: 1672: 1665: 1629: 1628: 1625: 1622: 1619: 1616: 1613: 1601: 1598: 1590:blood pressure 1586:cardiac muscle 1567:Mechanobiology 1549: 1546: 1545: 1544: 1533: 1530: 1527: 1524: 1519: 1515: 1511: 1506: 1502: 1498: 1495: 1490: 1485: 1481: 1455: 1451: 1430: 1427: 1422: 1418: 1397: 1394: 1391: 1380: 1379: 1367: 1362: 1355: 1351: 1346: 1343: 1338: 1333: 1329: 1325: 1320: 1315: 1311: 1307: 1302: 1297: 1293: 1286: 1282: 1279: 1275: 1271: 1268: 1263: 1257: 1253: 1249: 1243: 1240: 1237: 1219: 1216: 1215: 1214: 1202: 1198: 1195: 1188: 1185: 1181: 1175: 1172: 1168: 1162: 1159: 1156: 1153: 1149: 1144: 1139: 1135: 1130: 1127: 1122: 1119: 1105: 1104: 1091: 1088: 1084: 1078: 1075: 1071: 1065: 1062: 1059: 1056: 1052: 1046: 1043: 1038: 1035: 1020: 1017: 1013: 1012: 999: 994: 990: 987: 982: 979: 976: 971: 966: 962: 958: 953: 948: 944: 940: 935: 930: 926: 922: 919: 915: 910: 906: 903: 900: 897: 894: 889: 884: 880: 876: 871: 866: 862: 858: 853: 848: 844: 840: 837: 833: 827: 824: 819: 816: 791: 787: 774: 771: 754: 734: 712: 709: 706: 703: 699: 676: 673: 670: 667: 663: 640: 637: 633: 618: 617: 604: 601: 597: 591: 588: 584: 578: 575: 572: 569: 565: 561: 558: 552: 549: 545: 539: 536: 532: 526: 523: 520: 517: 513: 509: 506: 492: 491: 479: 474: 470: 467: 462: 458: 453: 449: 446: 443: 439: 433: 430: 425: 422: 400: 397: 372: 369: 360: 359: 348: 344: 340: 336: 332: 328: 323: 319: 313: 309: 302: 298: 294: 290: 286: 282: 258: 255: 235:incompressible 188:nylon stocking 167: 164: 135: 132: 73:fibrous tissue 26: 9: 6: 4: 3: 2: 3655: 3644: 3641: 3639: 3636: 3634: 3631: 3629: 3626: 3625: 3623: 3604: 3601: 3599: 3596: 3594: 3591: 3589: 3586: 3585: 3583: 3581: 3577: 3573: 3567: 3564: 3562: 3559: 3557: 3554: 3552: 3548: 3545: 3544: 3542: 3540: 3536: 3533: 3529: 3515: 3511: 3508: 3507: 3505: 3502: 3497: 3491: 3488: 3486: 3485:Metatarsalgia 3483: 3481: 3478: 3476: 3473: 3471: 3468: 3466: 3463: 3462: 3460: 3457: 3452: 3446: 3443: 3441: 3438: 3436: 3433: 3431: 3428: 3426: 3423: 3421: 3418: 3417: 3415: 3412: 3407: 3404: 3402: 3397: 3392: 3388: 3382: 3381:Hypermobility 3379: 3377: 3374: 3373: 3371: 3367: 3364: 3358: 3348: 3345: 3341: 3338: 3337: 3336: 3335:Synovial cyst 3333: 3329: 3326: 3324: 3321: 3319: 3316: 3314: 3311: 3309: 3306: 3304: 3301: 3299: 3296: 3294: 3291: 3290: 3289: 3286: 3285: 3283: 3281: 3277: 3269: 3266: 3265: 3264: 3263: 3259: 3258: 3255: 3252: 3248: 3245: 3244: 3243: 3242: 3238: 3237: 3234: 3233:Ganglion cyst 3231: 3229: 3226: 3222: 3219: 3217: 3214: 3212: 3209: 3208: 3207: 3206:Tenosynovitis 3203: 3200: 3199: 3197: 3195: 3191: 3188: 3182: 3178: 3171: 3166: 3164: 3159: 3157: 3152: 3151: 3148: 3132: 3129: 3127: 3124: 3122: 3119: 3118: 3116: 3114: 3110: 3104: 3101: 3099: 3096: 3095: 3093: 3091: 3087: 3075: 3072: 3070: 3067: 3065: 3062: 3061: 3060: 3057: 3053: 3050: 3048: 3045: 3044: 3043: 3040: 3039: 3037: 3035: 3031: 3023: 3020: 3018: 3015: 3014: 3013: 3010: 3008: 3005: 3004: 3002: 3000: 2996: 2993: 2991: 2987: 2984: 2980: 2964: 2961: 2959: 2956: 2952: 2949: 2947: 2944: 2943: 2942: 2939: 2937: 2934: 2932: 2929: 2928: 2927: 2924: 2920: 2917: 2916: 2915: 2912: 2910: 2907: 2906: 2904: 2902: 2898: 2892: 2889: 2888: 2886: 2884: 2880: 2877: 2875: 2869: 2859: 2856: 2854: 2851: 2850: 2848: 2846: 2842: 2836: 2833: 2831: 2828: 2826: 2823: 2821: 2818: 2816: 2813: 2811: 2808: 2807: 2805: 2801: 2798: 2796: 2792: 2789: 2785: 2779: 2776: 2774: 2771: 2769: 2766: 2765: 2763: 2759: 2755: 2748: 2743: 2741: 2736: 2734: 2729: 2728: 2725: 2718: 2713: 2709: 2708: 2695: 2691: 2684: 2676: 2672: 2668: 2664: 2657: 2649: 2645: 2640: 2635: 2631: 2627: 2623: 2619: 2615: 2611: 2604: 2596: 2592: 2588: 2584: 2577: 2575: 2565: 2560: 2556: 2552: 2548: 2544: 2540: 2533: 2525: 2521: 2517: 2513: 2509: 2505: 2501: 2497: 2490: 2482: 2478: 2474: 2470: 2466: 2462: 2458: 2454: 2451:(5): 050802. 2450: 2446: 2442: 2435: 2427: 2423: 2418: 2413: 2409: 2405: 2401: 2397: 2390: 2382: 2378: 2374: 2370: 2363: 2355: 2351: 2346: 2341: 2337: 2333: 2329: 2322: 2314: 2312:0-387-97947-6 2308: 2304: 2297: 2295: 2293: 2291: 2282: 2278: 2274: 2270: 2266: 2262: 2258: 2254: 2247: 2245: 2236: 2232: 2228: 2226:9781450310291 2222: 2218: 2214: 2210: 2203: 2194: 2189: 2186:(4): 87–101. 2185: 2181: 2177: 2170: 2162: 2160:3-540-21965-X 2156: 2152: 2145: 2137: 2135:0-07-143833-5 2131: 2127: 2120: 2112: 2108: 2104: 2103:"Soft Tissue" 2098: 2083: 2082:"Soft tissue" 2077: 2075: 2070: 2060: 2057: 2055: 2052: 2050: 2047: 2045: 2042: 2041: 2035: 2033: 2029: 2025: 2023: 2018: 2016: 2011: 2009: 2003: 2000: 1996: 1983: 1980: 1978: 1975: 1973: 1970: 1967: 1965: 1962: 1960: 1959: 1955: 1954: 1951: 1948: 1946: 1945:Not required 1943: 1941: 1940:Not required 1938: 1936: 1935:Not required 1933: 1931: 1928: 1926: 1925: 1921: 1920: 1917: 1914: 1912: 1911:Not required 1909: 1907: 1906:Not required 1904: 1902: 1899: 1897: 1894: 1892: 1891: 1887: 1886: 1883: 1880: 1878: 1877:Not required 1875: 1873: 1872:Not required 1870: 1868: 1865: 1863: 1860: 1858: 1857: 1853: 1852: 1849: 1846: 1844: 1841: 1839: 1836: 1834: 1831: 1829: 1826: 1824: 1823: 1819: 1818: 1815: 1812: 1810: 1809:100-1000 μm 1807: 1805: 1804:100-1000 μm 1802: 1800: 1799:10 μm-300 μm 1797: 1795: 1792: 1790: 1789: 1785: 1784: 1781: 1778: 1776: 1773: 1771: 1768: 1766: 1763: 1761: 1758: 1756: 1755: 1751: 1750: 1747: 1744: 1741: 1739: 1736: 1733: 1731: 1728: 1725: 1723: 1720: 1717: 1715: 1712: 1710: 1709: 1705: 1704: 1701: 1700: 1699: 1694: 1692: 1691: 1687: 1685: 1684: 1680: 1678: 1677: 1673: 1671: 1670: 1666: 1664: 1663: 1660: 1658: 1653: 1651: 1647: 1643: 1639: 1635: 1626: 1623: 1620: 1617: 1614: 1611: 1610: 1609: 1607: 1597: 1595: 1591: 1587: 1583: 1579: 1575: 1570: 1568: 1564: 1560: 1555: 1554:tropocollagen 1531: 1528: 1525: 1522: 1517: 1513: 1509: 1504: 1500: 1496: 1493: 1488: 1483: 1479: 1471: 1470: 1469: 1453: 1449: 1428: 1425: 1420: 1416: 1395: 1392: 1389: 1365: 1360: 1353: 1349: 1344: 1341: 1336: 1331: 1327: 1323: 1318: 1313: 1309: 1305: 1300: 1295: 1291: 1284: 1280: 1277: 1273: 1269: 1266: 1261: 1255: 1251: 1247: 1241: 1238: 1235: 1228: 1227: 1225: 1200: 1196: 1193: 1186: 1183: 1179: 1173: 1170: 1166: 1160: 1157: 1154: 1151: 1147: 1142: 1137: 1133: 1128: 1125: 1120: 1117: 1110: 1109: 1108: 1089: 1086: 1082: 1076: 1073: 1069: 1063: 1060: 1057: 1054: 1050: 1044: 1041: 1036: 1033: 1026: 1025: 1024: 1016: 997: 992: 988: 985: 977: 974: 969: 964: 960: 956: 951: 946: 942: 938: 933: 928: 924: 917: 913: 908: 904: 901: 895: 892: 887: 882: 878: 874: 869: 864: 860: 856: 851: 846: 842: 835: 831: 825: 822: 817: 814: 807: 806: 805: 789: 785: 770: 768: 752: 732: 710: 707: 704: 701: 697: 674: 671: 668: 665: 661: 638: 635: 631: 623: 602: 599: 595: 589: 586: 582: 576: 573: 570: 567: 563: 559: 556: 550: 547: 543: 537: 534: 530: 524: 521: 518: 515: 511: 507: 504: 497: 496: 495: 477: 472: 468: 465: 460: 456: 451: 447: 444: 441: 437: 431: 428: 423: 420: 413: 412: 411: 409: 405: 396: 394: 390: 386: 385:Physiologists 382: 378: 368: 366: 365:pseudoelastic 330: 311: 300: 284: 272: 271: 270: 268: 264: 254: 252: 248: 244: 240: 236: 232: 228: 224: 220: 212: 211:stretch ratio 208: 203: 199: 195: 193: 189: 185: 181: 180:strain energy 177: 173: 163: 161: 160:chondroblasts 157: 153: 149: 145: 141: 131: 129: 125: 121: 116: 114: 110: 106: 105:calcification 102: 98: 94: 90: 86: 82: 81:blood vessels 78: 74: 70: 66: 62: 58: 54: 51: 44: 40: 36: 32: 19: 3633:Biomechanics 3603:Knuckle pads 3576:Fibromatosis 3566:Eosinophilic 3500: 3455: 3445:Tennis elbow 3410: 3401:Tendinopathy 3391:Enthesopathy 3340:Baker's cyst 3303:Trochanteric 3260: 3239: 3194:Synoviopathy 2891:Tissue fluid 2767: 2717:Soft tissues 2693: 2683: 2666: 2662: 2656: 2621: 2617: 2603: 2586: 2582: 2546: 2542: 2532: 2499: 2495: 2489: 2448: 2444: 2434: 2399: 2389: 2372: 2368: 2362: 2335: 2331: 2321: 2302: 2256: 2252: 2208: 2202: 2183: 2179: 2169: 2150: 2144: 2125: 2119: 2106: 2097: 2085:. Retrieved 2049:Biomechanics 2026: 2019: 2012: 2004: 1994: 1993: 1982:Moderate 1981: 1976: 1971: 1963: 1957: 1956: 1949: 1944: 1939: 1934: 1929: 1923: 1922: 1915: 1910: 1905: 1900: 1895: 1889: 1888: 1881: 1876: 1871: 1866: 1861: 1855: 1854: 1847: 1842: 1837: 1832: 1827: 1821: 1820: 1813: 1808: 1803: 1798: 1793: 1787: 1786: 1779: 1774: 1769: 1764: 1759: 1753: 1752: 1745: 1742: 1737: 1734: 1729: 1726: 1721: 1718: 1713: 1707: 1706: 1696: 1695: 1689: 1688: 1682: 1681: 1675: 1674: 1668: 1667: 1654: 1634:segmentation 1630: 1603: 1571: 1551: 1381: 1106: 1022: 1014: 776: 619: 493: 406:developed a 402: 389:histologists 374: 364: 361: 267:precondition 266: 265:model after 263:hyperelastic 260: 237:and usually 231:viscoelastic 221:, and their 216: 196: 169: 137: 117: 101:ossification 49: 48: 18:Soft tissues 3628:Soft tissue 3580:contracture 3561:Necrotizing 3539:Fasciopathy 3360:Noncapsular 3308:Subacromial 3298:Prepatellar 3113:Specialized 3103:Mesenchymal 3074:Aponeurosis 2825:Tendon cell 2787:Composition 2768:Soft tissue 2054:Davis's law 2044:Biomaterial 1788:Penetration 1780:Moderate 1559:Wolff's law 239:anisotropic 209:(T) versus 156:fibroblasts 134:Composition 126:system and 50:Soft tissue 3622:Categories 3514:Tendinosis 3510:Tendinitis 3456:lower limb 3411:upper limb 3396:Enthesitis 3280:Bursopathy 2858:Macrophage 2835:Melanocyte 2810:Fibroblast 2761:Physiology 2589:: 97–129. 2151:Histologie 2065:References 2022:rheumatism 1896:Required 1867:Required 1760:Very High 1708:Resolution 1652:(<5%). 251:hysteresis 243:relaxation 120:mesenchyme 35:Micrograph 3547:Fasciitis 3490:Bone spur 3328:Iliopsoas 3293:Olecranon 3202:Synovitis 3121:Cartilage 3090:Embryonic 3047:Submucosa 3007:Reticular 2936:Fibrillin 2853:Mast cell 2830:Adipocyte 2815:Fibrocyte 2610:Kaplan DL 2481:244582251 2473:0003-6900 2375:: 59–61. 2338:: 22–50. 2281:108637580 1930:Required 1901:Required 1890:Embedding 1862:Required 1578:aneurisms 1523:− 1510:− 1501:λ 1480:λ 1390:μ 1342:− 1328:λ 1310:λ 1292:λ 1281:− 1270:⁡ 1248:μ 1242:− 1194:− 986:− 975:− 961:λ 943:λ 925:λ 893:− 879:λ 861:λ 843:λ 786:λ 466:− 322:→ 312:˙ 227:nonlinear 205:Graph of 184:composite 176:stiffness 170:At small 65:ligaments 3531:Nonjoint 3369:Symptoms 3313:Achilles 3288:Bursitis 3184:Capsular 3064:Ligament 2803:Resident 2778:Scarring 2773:Fibrosis 2694:UpToDate 2675:18204746 2648:18844604 2595:15923739 2524:25942366 2516:18209957 2426:31201857 2354:26144973 2235:34428866 2059:Rheology 2038:See also 1924:Staining 1856:Fixation 1754:Contrast 1714:0.25 μm 1676:Confocal 1642:formalin 1638:fixation 1594:arterial 1582:fibrosis 1574:stenosis 144:collagen 107:such as 97:hardened 53:connects 3556:Nodular 3551:Plantar 3323:Ischial 3012:Adipose 2963:Elaunin 2958:EMILIN1 2931:Elastin 2639:2817652 2551:Bibcode 2453:Bibcode 2417:6906264 2261:Bibcode 2087:13 July 1648:(10%), 1646:alcohol 765:is the 381:excised 172:strains 148:elastin 85:fasciae 61:tendons 3098:Mucoid 3069:Tendon 3052:Dermis 2990:Proper 2919:COL3A1 2901:Fibers 2874:matrix 2673:  2646:  2636:  2593:  2522:  2514:  2479:  2471:  2424:  2414:  2352:  2309:  2279:  2233:  2223:  2157:  2132:  2032:cancer 1848:Low 1770:High 1596:wall. 1382:where 93:tissue 87:, and 57:muscle 39:tendon 3362:joint 3186:joint 3131:Blood 3034:Dense 3022:White 3017:Brown 2999:Loose 2982:Types 2795:Cells 2520:S2CID 2477:S2CID 2277:S2CID 2231:S2CID 2109:. at 1977:High 1972:High 1828:High 1775:High 1765:Low 1650:bouin 494:with 247:creep 192:nylon 113:teeth 109:bones 77:lymph 37:of a 3126:Bone 2951:FBN3 2946:FBN2 2941:FBN1 2671:PMID 2644:PMID 2591:PMID 2512:PMID 2469:ISSN 2422:PMID 2350:PMID 2307:ISBN 2221:ISBN 2155:ISBN 2130:ISBN 2089:2020 1964:Low 1958:Cost 1843:Low 1838:Low 1833:Low 1794:N/A 1576:and 1426:> 1393:> 725:and 653:and 404:Fung 387:and 249:and 150:and 128:glia 111:and 79:and 2634:PMC 2626:doi 2587:113 2559:doi 2547:466 2504:doi 2461:doi 2412:PMC 2404:doi 2377:doi 2340:doi 2269:doi 2257:459 2213:doi 2188:doi 1657:ECM 1565:). 804:): 225:is 130:". 103:or 69:fat 3624:: 3549:: 2692:. 2667:16 2665:. 2642:. 2632:. 2622:14 2620:. 2616:. 2585:. 2573:^ 2557:. 2545:. 2541:. 2518:. 2510:. 2500:50 2498:. 2475:. 2467:. 2459:. 2449:73 2447:. 2443:. 2420:. 2410:. 2398:. 2373:69 2371:. 2348:. 2336:52 2334:. 2330:. 2289:^ 2275:. 2267:. 2255:. 2243:^ 2229:. 2219:. 2182:. 2178:. 2105:. 2073:^ 2017:. 1267:ln 689:, 395:. 383:. 245:, 233:, 146:, 115:. 83:, 75:, 71:, 67:, 63:, 59:, 41:. 3578:/ 3512:/ 3398:/ 3393:/ 3204:/ 3169:e 3162:t 3155:v 2746:e 2739:t 2732:v 2696:. 2677:. 2650:. 2628:: 2597:. 2567:. 2561:: 2553:: 2526:. 2506:: 2483:. 2463:: 2455:: 2428:. 2406:: 2383:. 2379:: 2356:. 2342:: 2315:. 2283:. 2271:: 2263:: 2237:. 2215:: 2196:. 2190:: 2184:2 2163:. 2138:. 2113:. 2091:. 1561:( 1532:1 1529:= 1526:3 1518:m 1514:J 1505:m 1497:2 1494:+ 1489:2 1484:m 1454:m 1450:J 1429:0 1421:m 1417:J 1396:0 1366:) 1361:) 1354:m 1350:J 1345:3 1337:2 1332:3 1324:+ 1319:2 1314:2 1306:+ 1301:2 1296:1 1285:( 1278:1 1274:( 1262:2 1256:m 1252:J 1239:= 1236:W 1201:) 1197:1 1187:l 1184:k 1180:E 1174:j 1171:i 1167:E 1161:l 1158:k 1155:j 1152:i 1148:b 1143:e 1138:( 1134:c 1129:2 1126:1 1121:= 1118:W 1090:l 1087:k 1083:E 1077:j 1074:i 1070:E 1064:l 1061:k 1058:j 1055:i 1051:a 1045:2 1042:1 1037:= 1034:W 1011:, 998:] 993:) 989:1 981:) 978:3 970:2 965:3 957:+ 952:2 947:2 939:+ 934:2 929:1 921:( 918:c 914:e 909:( 905:b 902:+ 899:) 896:3 888:2 883:3 875:+ 870:2 865:2 857:+ 852:2 847:1 839:( 836:a 832:[ 826:2 823:1 818:= 815:W 790:i 753:W 733:c 711:l 708:k 705:j 702:i 698:b 675:l 672:k 669:j 666:i 662:a 639:j 636:i 632:E 603:l 600:k 596:E 590:j 587:i 583:E 577:l 574:k 571:j 568:i 564:b 560:= 557:Q 551:l 548:k 544:E 538:j 535:i 531:E 525:l 522:k 519:j 516:i 512:a 508:= 505:q 478:] 473:) 469:1 461:Q 457:e 452:( 448:c 445:+ 442:q 438:[ 432:2 429:1 424:= 421:W 347:) 343:E 339:( 335:S 331:= 327:S 318:) 308:E 301:, 297:E 293:( 289:S 285:= 281:S 45:. 20:)

Index

Soft tissues

Micrograph
tendon
Hematoxylin and eosin stain
connects
muscle
tendons
ligaments
fat
fibrous tissue
lymph
blood vessels
fasciae
synovial membranes
tissue
hardened
ossification
calcification
bones
teeth
mesenchyme
reticuloendothelial
glia
extracellular matrix
collagen
elastin
ground substance
fibroblasts
chondroblasts

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