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650:- Edited the Introduction - Added a new photo for Pheo - Added an “also known as” with links to Paraganglioma and other PPGL genetic syndromes (like the influenza page) - NEW**Create an updated “grey box on the right hand side” that mirrors the starred wikipedia pages (see MS) - Edited the Signs and Symptoms
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This is a very unusual disorder and i believe it to be hereditary. I also will make the assuption that having this disease causes people to have a least one other disease from this disorder. This disease has not really been publically talked about wonder how many people get this disease and who is it
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Hello everyone! I added some information on the clinical implications of the endocrine effects of the tumors as well as details on the genetic side of things. I also added more detailed information on the imaging procedures used, specifically MIBG, and linked the iobenguane (compound used in MIBG)
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I have removed carcinoid syndrome from the differential diagnosis. Carcinoid syndrome is not associated with high blood pressure. Early writers, notably I. Page, speculated that it was because serotonin is a vasoconstrictor. The only blood pressure change associated with carcinoid syndrome is
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The
National Cancer Institute points out that this is a rare disease, with only 800 cases per year diagnosed in the USA. That should be pointed out in the article so people with common conditions (like generalized anxiety disorder) do not read this article and think they have a tumor.
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Very good idea. Phaeochromocytomas are, after all, chromaffin-positive neuroendocrine tumours. What distinguishes them from paragangliomas is not their site (both can be extra-adrenal), but the fact that phaeochromocytomas are chromaffin-positive, while paragangliomas are not.
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The MEN 2/3 disorder which is one of the causes is indeed hereditary, although i think it is more likely to be a multifactorial condition than a purely genetic one. I was also under the impression that 1st line treatment was adrenalectomy, and not tumour removal as stated here.
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I think it is very likely that, like me, many readers of this page were inspired to look here by the episode of House MD (S2.E1, "Acceptance") that mentions this condition. Does it warrant a "references in popular culture" section or something like it?
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and "writing for the wrong audience. There is good material here, but the primary sources need to be replaced with secondary sources, and an encyclopedic tone adopted. There are many other issues I haven't detailed, but this is a start.
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I will be posting a weekly work plan to address the various changes I will be making as a part of the a Med
Communications Knowledge Course I am currently taking part of. Please see below for 8/7 to 8/14 agenda
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Naturally, please note, etc-- to be avoided in encyclopedic writing, which is different than term paper writing or essay writing. In encyclopedic writing, the goal is not to convince but to summarize secondary
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I suggest that this article mention the word "chromaffinoma", and either list it as a synonym or disambiguate the terms, so that this article can be found by searching for this term.
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659:- HTN crisis; recognition, management, and prevention - Move the differential diagnosis to this section - Remove the various genetic syndromes from differential
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Article says, "The tumors are made up of large, polyhedral, pleomorphic chromaffin cells. Fewer than 10% of these are malignant." Does this mean that fewer than 10% of the
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The entire
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eochromocytoma" - be used for the title and in the article, with a redirect from the US spelling ("Pheochromocytoma"), rather than the other war round?
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issues, but more significantly, the tone and sourcing issues should be cleaned up before this article could be assessed to B class. Please consult
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Given the ending of "a", what is the plural or collective name ? "phaeochromocytomae" ("ae" being pronounced as in "eye") or "phaeochromocytomas" ?
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I started listing cleanup needs, but have been called away; will add a more detailed explanation here later. For now, there are considerable
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is off-topic. That
Gallery *might* be appropriate at a more general imaging article, but is not appropriate here. Similar advice issue
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Surely we have better info by now, and if this info is still relevant and significant, it would be mentioned in a secondary source.
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Here is an example of NOTADVICE and excess bolding combined to affect the tone (writing for the wrong audience):
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hypotension which occurs during the flush; it is caused by bradykinin, a most powerful vasodilator.
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This article was the subject of a Wiki
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page for more information. If there are any inaccuracies, feel free to edit. Happy editing!!
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These are samples only; the problems are throughout. To receive a B-class assessment,
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if this information were relevant, it would be mentioned in a secondary review, see
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is unhelpful to readers in a dynamic environment ... remains since when? See
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