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its microarchitecture. Bone microarchitecture is related to the mechanical strength of bone and hence its greater or lesser risk of fracture. Indeed, for the same quantity of bone, different mechanically resistant bone structures may exist (few large trabeculae or numerous thin trabeculae that are mechanically stronger). Actually, bone loss is often accompanied by a deterioration of bone architecture, resulted in a decreased number of trabeculae, increased inter-trabecular distances, and a loss connectivity of the trabecular meshwork. Moreover, reduction of
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is an assessment of the quantity of bone. It does not provide information on bone quality, another important parameter to describe the bone. In addition, clinical risk factors for fracture are at best an indirect assessment of the bone quality. One way to describe the quality of the bone is to assess
280:
Hans, Didier; Barthe, Nicole; Boutroy, Stephanie; Pothuaud, Laurent; Winzenrieth, Renaud; Krieg, Marc-Antoine (2011). "Correlations
Between Trabecular Bone Score, Measured Using Anteroposterior Dual-Energy X-Ray Absorptiometry Acquisition, and 3-Dimensional Parameters of Bone Microarchitecture: An
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and their connectivity and negatively with the space between trabeculae. That is to say that a high TBS value means that microarchitecture bone is dense, well connected with little spaces between trabeculaes. Conversely, a low TBS value means that the microarchitecture of bone is incomplete and
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All these studies have shown that TBS can be used as a clinical risk factor for osteoporotic fracture since it is reversible (with or without treatment), quantitative and independent of BMD. It should therefore be used as such in the same way that taking
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Winzenrieth, Renaud; Dufour, RĂ©my; Pothuaud, Laurent; Hans, Didier (2009). "A Retrospective CaseâControl Study
Assessing the Role of Trabecular Bone Score in Postmenopausal Caucasian Women with Osteopenia: Analyzing the Odds of Vertebral Fracture".
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Pothuaud, Laurent; Barthe, Nicole; Krieg, Marc-Antoine; Mehsen, Nadia; Carceller, Pascal; Hans, Didier (2009). "Evaluation of the
Potential Use of Trabecular Bone Score to Complement Bone Mineral Density in the Diagnosis of Osteoporosis:
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Pothuaud, Laurent; Carceller, Pascal; Hans, Didier (2008). "Correlations between grey-level variations in 2D projection images (TBS) and 3D microarchitecture: Applications in the study of human trabecular bone microarchitecture".
522:
Eller-Vainicher, Cristina; Morelli, Valentina; Ulivieri, Fabio
Massimo; Palmieri, Serena; Zhukouskaya, Volha V.; Cairoli, Elisa; Pino, Rosa; Naccarato, Antonella; Scillitani, Alfredo; Beck-Peccoz, Paolo; Chiodini, Iacopo (2012).
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Piveteau, Teddy; Winzenrieth, Renaud; Hans, Didier (2011). "Assessment of correlations between 3D ÎŒCT microarchitecture parameters and TBS: Effects of resolution and correlation with TBS DXA measurements".
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calculator has an option to include TBS for a TBS adjusted FRAX risk score. The calculated probabilities of fracture have been shown to be more accurate when computed including TBS.
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thickness and increased porosity accompany trabecular bone loss, and in particular promote the fragility of the femoral neck. Osteoporotic bone is called "porous".
151:, which quantifies the local variations in gray level. TBS is derived from the evaluation of the experimental variogram, obtained from the grayscale DEXA.
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Shevroja, Enisa; AubryâRozier, BĂ©rengĂšre; Hans, Gabriel; GonzalezâRodriguez, Elena; Stoll, Delphine; Lamy, Olivier; Hans, Didier (December 2019).
525:"Bone quality, as measured by trabecular bone score (TBS), in patients with adrenal incidentalomas with and without subclinical hypercortisolism"
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It was found that TBS is a reflection of the structural condition of the bone microarchitecture. TBS is strongly correlated with the number of
596:"Clinical Performance of the Updated Trabecular Bone Score (TBS) Algorithm, Which Accounts for the Soft Tissue Thickness: The OsteoLaus Study"
122:(BMD), biological markers and clinical factors of fracture risk, many not detected patients are at risk and many fractures are not explained.
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Stokar, Joshua; Ben-Porat, Tair; Kaluti, Donia; Abu-Gazala, Mahmud; Weiss, Ram; Mintz, Yoav; Elazari, Ram; Szalat, Auryan (January 2023).
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Relative Risk of TBS expressed by standard deviation and compared with relative risks of major clinical risk factors for fracture
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349:"Bone microarchitecture assessed by TBS predicts osteoporotic fractures independent of bone density: The manitoba study"
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653:"Trabecular Bone Score Preceding and during a 2-Year Follow-Up after Sleeve Gastrectomy: Pitfalls and New Insights"
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Rio, L. M.; Winzenrieth, R.; Cormier, C.; Gregorio, S. (2012). "Is bone microarchitecture status of
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As TBS relies on measurement of soft tissue, it is considered unreliable in individuals with a
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in combination with BMD, increase the number of patients at risk (correctly) identified;
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spine assessed by TBS related to femoral neck fracture? A Spanish caseâcontrol study".
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texture correlated with bone microarchitecture and a marker for the risk of
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in better predicting fracture risk in people with metabolic bone problems.
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The trabecular bone score is a textural parameter that can be applied to
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follow-up of the evolution of microarchitecture of a patient over time;
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improvement the management of patients with secondary osteoporosis;
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monitoring of the effect of anti-resorptive or anabolic.
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Microarchitecture of bone in health and in osteoporosis.
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poorly connected with wide spaces between trabeculae.
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281:Experimental Study on Human Cadaver Vertebrae".
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167:From a clinical standpoint, TBS provides:
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225:TBS â main guidelines and fields of usage
102:Learn how and when to remove this message
396:spine BMDâMatched, Case-Control Study".
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36:Need for a marker of microarchitecture
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398:Journal of Clinical Densitometry
319:Journal of Clinical Densitometry
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295:10.1016/j.jocd.2011.05.005
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18:trabecular bone score
231:Notes and references
124:Bone mineral density
120:bone mineral density
76:improve this section
208:waist circumference
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92:August 2012
477:the lumbar
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657:Nutrients
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63:does not
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573:Archived
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