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Type II collagen

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have been reported to have positive impact on skin health. A review and analysis of 19 studies found that participants who used collagen supplements saw an improvement in the firmness, suppleness, and moisture content of the skin, with wrinkles appearing less noticeable. There is still a need for
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aggregate, as well as providing tensile strength to the tissue. Oral administration of native type II collagen induces oral tolerance to pathological immune responses and may be useful in arthritis.
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Park KS, Park MJ, Cho ML, Kwok SK, Ju JH, Ko HJ, Park SH, Kim HY (2009). "Type II collagen oral tolerance; mechanism and role in collagen-induced arthritis and rheumatoid arthritis".
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collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)
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Bakilan F, Armagan O, Ozgen M, Tascioglu F, Bolluk O, Alatas O (June 2016).
954: 326: 269: 200: 377: 1032: 961: 697: 642: 103: 173:, including the articular cartilages at joint surfaces. It is formed by 663: 174: 98: 346:
Hector's research on the impact of collagen supplements on skin health
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large, high-quality studies to determine the scientific impact of
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Basis for articular and hyaline cartilage in animals
1131: 247: 188:and 85–90% of collagen of articular cartilage. 1114: 393: 407: 1121: 1107: 400: 386: 370:at the U.S. National Library of Medicine 316: 430: 1132: 381: 1069: 1048:Cartilage oligomeric matrix protein 199:allows the cartilage to entrap the 191:Type II collagen is organised into 13: 339: 184:It makes up 50% of all protein in 14: 1161: 361: 1073: 297:The Eurasian Journal of Medicine 309:10.5152/eurasianjmed.2015.15030 1150:Human chromosome 12 gene stubs 333: 284: 241: 1: 235: 1140:Genes on human chromosome 12 1093:. You can help Knowledge by 812:Cartilage associated protein 215:supplements on skin health. 195:. This fibrillar network of 7: 230:Collagen, type III, alpha 1 218: 10: 1166: 1068: 179:collagen, type II, alpha 1 1021: 937: 843: 793: 522: 439: 419: 262:10.1007/s10165-009-0210-0 150: 140: 135: 131: 114: 109: 97: 85: 73: 61: 49: 41: 31: 26: 21: 372:Medical Subject Headings 206:Supplements containing 342:"Hector Collagen Plus" 826:Procollagen peptidase 250:Modern Rheumatology 1081:This article on a 992:Matrix gla protein 803:Prolyl hydroxylase 340:Hubert, Flemming. 1102: 1101: 1066: 1065: 1017: 1016: 839: 838: 807:Lysyl hydroxylase 598:basement membrane 171:hyaline cartilage 169:is the basis for 164: 163: 160: 159: 1157: 1123: 1116: 1109: 1077: 1070: 437: 436: 428: 427: 402: 395: 388: 379: 378: 368:Collagen+type+II 356: 355: 353: 352: 337: 331: 330: 320: 288: 282: 281: 245: 213:Type II collagen 208:Type II collagen 167:Type II collagen 133: 132: 19: 18: 1165: 1164: 1160: 1159: 1158: 1156: 1155: 1154: 1130: 1129: 1128: 1127: 1067: 1062: 1013: 933: 835: 789: 672:transmembrane: 518: 422: 415: 406: 364: 359: 350: 348: 338: 334: 289: 285: 246: 242: 238: 225:Type I collagen 221: 17: 12: 11: 5: 1163: 1153: 1152: 1147: 1142: 1126: 1125: 1118: 1111: 1103: 1100: 1099: 1078: 1064: 1063: 1061: 1060: 1055: 1051: 1050: 1045: 1040: 1035: 1025: 1023: 1019: 1018: 1015: 1014: 1012: 1011: 1010: 1009: 1004: 994: 989: 984: 979: 974: 969: 964: 959: 958: 957: 947: 941: 939: 935: 934: 932: 931: 930: 929: 924: 919: 909: 908: 907: 902: 897: 892: 882: 881: 880: 875: 870: 865: 860: 849: 847: 841: 840: 837: 836: 834: 833: 828: 823: 818: 809: 799: 797: 791: 790: 788: 787: 782: 777: 776: 775: 770: 760: 750: 749: 748: 743: 733: 723: 722: 721: 716: 711: 706: 692: 691: 686: 681: 676: 669: 668: 667: 666: 661: 649: 639: 638: 637: 636: 631: 626: 621: 616: 611: 594: 593: 588: 583: 578: 573: 568: 563: 553: 552: 551: 546: 541: 526: 524: 520: 519: 517: 516: 511: 506: 505: 504: 499: 494: 482: 475: 463: 462: 461: 456: 443: 441: 440:Fibril forming 434: 425: 421:Extracellular 417: 416: 413:scleroproteins 405: 404: 397: 390: 382: 376: 375: 363: 362:External links 360: 358: 357: 332: 283: 239: 237: 234: 233: 232: 227: 220: 217: 162: 161: 158: 157: 152: 148: 147: 142: 138: 137: 129: 128: 118: 112: 111: 107: 106: 101: 95: 94: 89: 83: 82: 77: 71: 70: 65: 59: 58: 53: 47: 46: 43: 39: 38: 33: 29: 28: 24: 23: 15: 9: 6: 4: 3: 2: 1162: 1151: 1148: 1146: 1143: 1141: 1138: 1137: 1135: 1124: 1119: 1117: 1112: 1110: 1105: 1104: 1098: 1096: 1092: 1088: 1087:chromosome 12 1084: 1079: 1076: 1072: 1071: 1059: 1056: 1053: 1052: 1049: 1046: 1044: 1041: 1039: 1036: 1034: 1030: 1027: 1026: 1024: 1020: 1008: 1005: 1003: 1000: 999: 998: 995: 993: 990: 988: 985: 983: 980: 978: 975: 973: 970: 968: 965: 963: 960: 956: 953: 952: 951: 948: 946: 943: 942: 940: 936: 928: 925: 923: 920: 918: 915: 914: 913: 910: 906: 903: 901: 898: 896: 893: 891: 888: 887: 886: 883: 879: 876: 874: 871: 869: 866: 864: 861: 859: 856: 855: 854: 851: 850: 848: 846: 842: 832: 831:Lysyl oxidase 829: 827: 824: 822: 819: 817: 813: 810: 808: 804: 801: 800: 798: 796: 792: 786: 783: 781: 778: 774: 771: 769: 766: 765: 764: 761: 758: 754: 751: 747: 744: 742: 739: 738: 737: 734: 731: 727: 724: 720: 717: 715: 712: 710: 707: 705: 702: 701: 700: 699: 694: 693: 690: 687: 685: 682: 680: 677: 675: 671: 670: 665: 662: 660: 657: 656: 655: 654: 650: 648: 644: 641: 640: 635: 632: 630: 627: 625: 622: 620: 617: 615: 612: 610: 607: 606: 605: 604: 599: 596: 595: 592: 589: 587: 584: 582: 579: 577: 574: 572: 569: 567: 564: 561: 557: 554: 550: 547: 545: 542: 540: 537: 536: 535: 531: 528: 527: 525: 521: 515: 512: 510: 507: 503: 500: 498: 495: 493: 490: 489: 488: 487: 483: 481: 480: 476: 473: 469: 468: 464: 460: 457: 455: 452: 451: 450: 449: 445: 444: 442: 438: 435: 433: 429: 426: 424: 418: 414: 410: 403: 398: 396: 391: 389: 384: 383: 380: 373: 369: 366: 365: 347: 343: 336: 328: 324: 319: 314: 310: 306: 303:(2): 95–101. 302: 298: 294: 287: 279: 275: 271: 267: 263: 259: 255: 251: 244: 240: 231: 228: 226: 223: 222: 216: 214: 209: 204: 202: 198: 194: 189: 187: 182: 180: 176: 172: 168: 156: 153: 149: 146: 143: 139: 134: 130: 127: 126: 122: 119: 117: 113: 108: 105: 102: 100: 96: 93: 90: 88: 84: 81: 78: 76: 72: 69: 66: 64: 60: 57: 54: 52: 48: 44: 40: 37: 34: 30: 25: 20: 1095:expanding it 1080: 955:Tropoelastin 911: 884: 852: 762: 752: 735: 725: 696: 651: 601: 555: 533: 484: 477: 465: 446: 349:. Retrieved 345: 335: 300: 296: 286: 256:(6): 581–9. 253: 249: 243: 212: 207: 205: 201:proteoglycan 190: 183: 166: 165: 125:q13.11-q13.2 123: 42:Alt. symbols 1033:Cytokeratin 962:Vitronectin 643:multiplexin 175:homotrimers 145:Swiss-model 27:Identifiers 1134:Categories 664:Endostatin 653:type XVIII 351:2022-12-10 236:References 141:Structures 136:Search for 110:Other data 1145:Collagens 1085:on human 1043:Reticulin 736:type VIII 278:207061498 186:cartilage 92:NM_001844 51:NCBI gene 1058:diseases 1054:See also 997:Tectorin 816:Leprecan 726:type VII 556:type XII 479:type III 432:Collagen 327:27551171 270:19697097 219:See also 197:collagen 181:chains. 155:InterPro 1038:Gelatin 1029:Keratin 977:Decorin 950:Elastin 845:Laminin 821:ADAMTS2 795:Enzymes 785:COL28A1 780:COL27A1 773:COL11A2 768:COL11A1 763:type XI 757:COL10A1 698:type VI 695:other: 689:COL25A1 684:COL23A1 679:COL17A1 674:COL13A1 659:COL18A1 647:COL15A1 603:type IV 591:COL22A1 586:COL21A1 581:COL20A1 576:COL19A1 571:COL16A1 566:COL14A1 560:COL12A1 534:type IX 514:COL26A1 509:COL24A1 467:type II 409:Protein 318:4970562 193:fibrils 151:Domains 121:Chr. 12 99:UniProt 982:FAM20C 753:type X 746:COL8A2 741:COL8A1 730:COL7A1 719:COL6A5 714:COL6A3 709:COL6A2 704:COL6A1 634:COL4A6 629:COL4A5 624:COL4A4 619:COL4A3 614:COL4A2 609:COL4A1 549:COL9A3 544:COL9A2 539:COL9A1 502:COL5A3 497:COL5A2 492:COL5A1 486:type V 472:COL2A1 459:COL1A2 454:COL1A1 448:type I 423:matrix 374:(MeSH) 325:  315:  276:  268:  104:P02458 87:RefSeq 80:120140 36:COL2A1 32:Symbol 1089:is a 1022:Other 1007:TECTB 1002:TECTA 972:FREM2 967:FRAS1 945:ALCAM 938:Other 927:LAMC3 922:LAMC2 917:LAMC1 912:gamma 905:LAMB4 900:LAMB3 895:LAMB2 890:LAMB1 878:LAMA5 873:LAMA4 868:LAMA3 863:LAMA2 858:LAMA1 853:alpha 530:FACIT 523:Other 274:S2CID 116:Locus 1091:stub 1083:gene 987:ECM1 885:beta 323:PMID 266:PMID 75:OMIM 68:2200 63:HGNC 56:1280 45:SEDC 313:PMC 305:doi 258:doi 177:of 1136:: 645:: 600:: 532:: 411:: 344:. 321:. 311:. 301:48 299:. 295:. 272:. 264:. 254:19 252:. 1122:e 1115:t 1108:v 1097:. 1031:/ 814:/ 805:/ 759:) 755:( 732:) 728:( 562:) 558:( 474:) 470:( 401:e 394:t 387:v 354:. 329:. 307:: 280:. 260::

Index

COL2A1
NCBI gene
1280
HGNC
2200
OMIM
120140
RefSeq
NM_001844
UniProt
P02458
Locus
Chr. 12
q13.11-q13.2
Swiss-model
InterPro
hyaline cartilage
homotrimers
collagen, type II, alpha 1
cartilage
fibrils
collagen
proteoglycan
Type I collagen
Collagen, type III, alpha 1
doi
10.1007/s10165-009-0210-0
PMID
19697097
S2CID

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