250:
Diagnosis of a vasculitic neuropathy depends on whether the patient first presents with multiple symptoms pointing at a systemic disorder or else primary neuropathic complaints. In the former case the patient is more likely to be assessed first by a rheumatologist and in the latter a neurologist or
191:
Non-systemic vasculitic neuropathy (NSVN) is a diagnosis of elimination. When no systemic illness can be found, yet evidence of a vasculitic neuropathy exists, a diagnosis of non-systemic vasculitic neuropathy is made. It is a single-organ problem. A nerve biopsy is required in order to make the
241:
Postsurgical inflammatory neuropathy is typically a multi-focal neuropathy which manifests thirty days after a surgical procedure. It mostly presents with motor and sensory symptoms. It is generally a self-limiting condition that has resolved with and without treatment.
223:
There is an ongoing debate over this categorisation, particularly its overlap with the condition non-diabetic radiculoplexus neuropathy. This neuropathy involves a clinical picture where the nerve damage is distally predominant as demonstrated in a nerve biopsy.
85:
Some patients with systemic vasculitis will have their multi-organ disease spread to the peripheral nervous system; this is primary vasculitic neuropathy. Some examples of systemic vasculitic disease are: IgA vasculitis, Hypocomplementemic urticarial vasculitis,
232:
Warternberg migratory sensory neuropathy is typically a multi-focal neuropathy where there is pure sensory deficits. It is characterised by sudden-onset and chronicity as well as having a propensity for relapse. It generally resolves slowly with time.
65:, nerve biopsy and clinical examination. It is a serious medical condition that can cause prolonged morbidity and disability and generally requires treatment. Treatment depends on the type but it is mostly with
122:
can subsequently develop vasculitic neuropathy as a direct consequence of the former illness; this is secondary vasculitic neuropathy. Some examples of such illness which can cause vasculitic neuropathy are:
99:
477:
91:
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There are distinct subtypes of NSVN with evolving categorisation in the literature. Currently accepted subtypes are:
349:"Update on classification, epidemiology, clinical phenotype and imaging of the nonsystemic vasculitic neuropathies"
95:
132:
472:
54:
103:
53:. It can be as part of a systemic problem or can exist as a single-organ issue only affecting the
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There are three main categories of vasculitic neuropathies: primary, secondary and non-systemic.
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42:
128:
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8:
136:
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27:
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Diabetic radiculoplexus neuropathy (lumbosacral, thoracic or cervical predominant)
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Some patients with a non-vasculitic systemic disease or another illness such as
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66:
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Collins, Michael P.; Dyck, P. James B.; Hadden, Robert D.M. (October 2019).
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neuropathy there is damage to the vessels that supply blood to the
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Non-systemic skin/nerve vasculitis (for example, cutaneous PAN)
50:
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80:
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Treatment of vasculitic neuropathy depends on the type.
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Drugs (amphetamines, sympathomimetics, cocaine, etc.)
417:Collins, Michael P.; Hadden, Robert D. (May 2017).
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192:diagnosis of non-systemic vasculitic neuropathy.
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110:Vasculitic neuropathy secondary to other disease
283:Graf, Jonathan; Imboden, John (January 2019).
416:
100:eosinophilic granulomatosis with polyangiitis
282:
434:
419:"The nonsystemic vasculitic neuropathies"
228:Warternberg migratory sensory neuropathy
202:Wartenberg migratory sensory neuropathy
94:(ANCA) associated vasculitides such as
57:(PNS). It is diagnosed with the use of
465:
285:"Vasculitis and peripheral neuropathy"
166:, human T-cell-lymphotrophic virus-I,
81:Primary systemic vasculitic neuropathy
205:Post-surgical inflammatory neuropathy
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237:Postsurgical inflammatory neuropathy
92:anti-neutrophil cytoplasmic antibody
478:Peripheral nervous system disorders
219:'Classical' distal-predominant NSVN
199:'Classical' distal-predominant NSVN
13:
187:Non-systemic vasculitic neuropathy
14:
489:
395:
331:
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96:granulomatosis with polyangiitis
289:Current Opinion in Rheumatology
69:or immunomodulating therapies.
43:peripheral neuropathic disease
1:
262:
254:
365:10.1097/WCO.0000000000000727
353:Current Opinion in Neurology
301:10.1097/BOR.0000000000000559
245:
156:human immunodeficiency virus
133:systemic lupus erythematosus
127:Connective tissue diseases:
7:
10:
494:
55:peripheral nervous system
26:
21:
436:10.1038/nrneurol.2017.42
423:Nature Reviews Neurology
104:microscopic polyangiitis
72:
146:Infectious diseases:
39:Vasculitic neuropathy
22:Vasculitic neuropathy
211:Neuralgic amyotrophy
129:rheumatoid arthritis
88:polyarteritis nodosa
59:electrophysiological
473:Vascular diseases
137:primary sjögren's
36:
35:
16:Medical condition
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160:cytomegalovirus
141:dermatomyositis
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83:
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67:corticosteroids
17:
12:
11:
5:
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429:(5): 302–316.
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359:(5): 684–695.
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251:neurosurgeon.
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168:parvovirus B19
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295:(1): 40–45.
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180:Vaccinations
164:lyme disease
113:
84:
76:
38:
37:
173:Malignancy.
152:hepatitis C
148:hepatitis B
102:(EGPA) and
63:blood tests
467:Categories
263:References
255:Treatments
120:malignancy
90:(PAN) and
47:vasculitic
445:1759-4758
389:197423473
373:1350-7540
309:1040-8711
246:Diagnosis
116:infection
61:testing,
32:Neurology
28:Specialty
453:28447661
381:31313704
325:53943955
317:30461543
158:(HIV),
106:(MPA).
98:(GPA),
45:. In a
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443:
387:
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371:
323:
315:
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51:nerves
385:S2CID
321:S2CID
73:Types
41:is a
449:PMID
441:ISSN
377:PMID
369:ISSN
313:PMID
305:ISSN
431:doi
361:doi
297:doi
118:or
469::
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427:13
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397:^
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367:.
357:32
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351:.
333:^
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293:31
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271:^
162:,
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131:,
455:.
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143:.
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