147:
1838:
492:
138:
748:
Garcia-Vaquero, M.; Rajauria, G.; O'Doherty, J.V.; Sweeney, T. (2017-09-01). "Polysaccharides from macroalgae: Recent advances, innovative technologies and challenges in extraction and purification".
866:"The O-linked fucose glycosylation pathway: identification and characterization of a uridine diphosphoglucose: fucose-1,3-glucosyltransferase activity from Chinese hamster ovary cells"
983:
Dalziel, Martin; Crispin, Max; Scanlan, Christopher N.; Zitzmann, Nicole; Dwek, Raymond A. (2014-01-03). "Emerging
Principles for the Therapeutic Exploitation of Glycosylation".
632:
In the fucose-containing glycan structures, fucosylated glycans, fucose can exist as a terminal modification or serve as an attachment point for adding other sugars. In human
810:
856:
259:
505:
687:
have been designed to recruit the immune system to cancers cells have been manufactured in cell lines deficient in the enzyme for core fucosylation (
413:
969:
680:
1102:
725:
684:
108:
378:
512:
500:
104:
618:
614:
1035:
956:
Vanhooren, PT (1999). "L-fucose: occurrence, physiological role, chemical, enzymatic and microbial synthesis".
82:
37:
173:
355:
604:
Two structural features distinguish fucose from other six-carbon sugars present in mammals: the lack of a
1095:
299:
645:
71:
26:
1162:
665:-Fucose has several potential applications in cosmetics, pharmaceuticals, and dietary supplements
637:
1655:
1841:
1649:
1088:
1867:
1643:
907:"Exopolysaccharides enriched in rare sugars: bacterial sources, production, and applications"
861:
159:
1862:
1782:
364:
319:
235:
8:
676:
225:
63:
1872:
1066:
1016:
933:
906:
791:
720:
474:
279:
78:
33:
1058:
1020:
1008:
1000:
938:
887:
837:
783:
775:
21:
795:
1235:
1070:
1050:
992:
965:
928:
918:
877:
827:
765:
757:
594:
535:
436:
761:
644:. However, fucose at the non-reducing termini linked Ξ±-1,2 to galactose forms the
344:
1684:
1630:
1610:
1501:
551:
652:
1671:
1468:
1225:
1202:
1182:
636:-linked glycans, fucose is most commonly linked Ξ±-1,6 to the reducing terminal
576:
483:
1054:
146:
1856:
1777:
1694:
1582:
1473:
1004:
923:
882:
865:
779:
569:
996:
832:
815:
387:
InChI=1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3+,4+,5-,6?/m0/s1
1661:
1542:
1524:
1172:
1112:
1062:
1012:
942:
891:
841:
787:
668:
587:
397:
InChI=1/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3+,4+,5-,6?/m0/s1
970:
10.1002/(SICI)1097-4660(199906)74:6<479::AID-JCTB76>3.0.CO;2-E
747:
1819:
1807:
1679:
1590:
1338:
1333:
1273:
1080:
1036:"Improving Antibody-Based Cancer Therapeutics Through Glycan Engineering"
672:
609:
531:
1595:
1537:
1532:
1405:
1358:
715:
700:
651:
Fucose is released from fucose-containing polymers by an enzyme called
459:
310:
859:
770:
1753:
1749:
1704:
1618:
1600:
1567:
1552:
1373:
1296:
1258:
626:
482:
Except where otherwise noted, data are given for materials in their
1770:
1731:
1716:
1689:
1638:
1572:
1445:
1440:
1425:
1410:
1326:
1321:
1141:
1136:
656:
605:
579:
121:
258:
1812:
1792:
1760:
1735:
1725:
1721:
1699:
1562:
1557:
1547:
1457:
1420:
1415:
1393:
1378:
1368:
1285:
1263:
1247:
710:
608:
group on the carbon at the 6-position (C-6) (thereby making it a
598:
590:
573:
331:
1802:
1797:
1787:
1764:
1741:
1709:
1496:
1491:
1398:
1383:
1363:
1350:
1311:
1306:
1301:
1214:
1167:
1157:
1131:
1126:
583:
562:
558:
528:
290:
809:
1388:
1191:
982:
566:
270:
248:
855:
813:
671:
of antibodies has been established to reduce binding to the
688:
137:
1034:
Yu, X; Marshall, MJE; Cragg, MS; Crispin, M (June 2017).
816:"Fucose: biosynthesis and biological function in mammals"
648:, the substructure of the A and B blood group antigens.
1033:
111:| Latest revision (diff) | Newer revision β (diff)
1854:
343:
691:), thereby enhancing the in vivo cell killing.
234:
69:
1096:
814:Daniel J. Becker; John B. Lowe (July 2003).
17:
1110:
1103:
1089:
572:Fucose is the fundamental sub-unit of the
318:
955:
932:
922:
881:
831:
769:
363:
47:
681:antigen-dependent cellular cytotoxicity
14:
1855:
1084:
1027:
390:Key: SHZGCJCMOBCMKK-DHVFOXMCSA-N
298:
278:
70:Revision as of 21:00, 12 May 2024 by
44:
25:
904:
400:Key: SHZGCJCMOBCMKK-DHVFOXMCBB
334:
117:
102:
685:afucosylated monoclonal antibodies
118:
1884:
62:. The present address (URL) is a
1837:
1836:
854:
808:
586:core of fucoidan is a suspected
490:
145:
136:
486:(at 25 Β°C , 100 kPa).
976:
949:
898:
848:
802:
741:
621:. It is equivalent to 6-deoxy-
13:
1:
762:10.1016/j.foodres.2016.11.016
734:
958:J. Chem. Technol. Biotechnol
7:
750:Food Research International
694:
24:of this page, as edited by
10:
1889:
464:164.16 g/mol
119:
89:
50:
1832:
1670:
1627:
1609:
1581:
1523:
1516:
1484:
1456:
1349:
1284:
1246:
1213:
1190:
1181:
1150:
1119:
1055:10.1007/s40259-017-0223-8
679:cells and thereby reduce
480:
473:
468:
429:
409:
374:
218:
206:
172:
158:
153:
144:
135:
1163:Cyclohexane conformation
924:10.3389/fmicb.2015.00288
469:Supplementary data page
120:Not to be confused with
91:
52:
1656:Isomaltooligosaccharide
997:10.1126/science.1235681
1650:Galactooligosaccharide
883:10.1093/glycob/9.7.679
703:, the methyl ether of
200:-pyran-2,3,4,5-tetraol
1644:Fructooligosaccharide
862:Robert S. Haltiwanger
833:10.1093/glycob/cwg054
194:)-6-Methyltetrahydro-
174:Systematic IUPAC name
726:Verotoxin-producing
860:Daniel J. Moloney;
756:(Pt 3): 1011β1020.
132:
109:β Previous revision
721:Fucosyltransferase
642:-acetylglucosamine
550:. It is found on
513:Infobox references
475:Fucose (data page)
127:
45:21:00, 12 May 2024
1850:
1849:
1828:
1827:
1512:
1511:
991:(6166): 1235681.
706:
664:
617:
521:Chemical compound
519:
518:
260:Interactive image
166:
1880:
1840:
1839:
1631:oligosaccharides
1611:Tetrasaccharides
1521:
1520:
1236:Dihydroxyacetone
1188:
1187:
1105:
1098:
1091:
1082:
1081:
1075:
1074:
1040:
1031:
1025:
1024:
980:
974:
973:
953:
947:
946:
936:
926:
905:Roca, C (2015).
902:
896:
895:
885:
858:
852:
846:
845:
835:
812:
806:
800:
799:
773:
745:
728:Escherichia coli
704:
662:
624:
613:
536:chemical formula
503:
497:
494:
493:
437:Chemical formula
367:
347:
336:
322:
302:
282:
262:
238:
212:
195:
167:-galactopyranose
164:
149:
140:
133:
130:
126:
99:
97:
95:
86:
66:to this version.
61:
60:
58:
56:
46:
42:
41:
22:current revision
1888:
1887:
1883:
1882:
1881:
1879:
1878:
1877:
1853:
1852:
1851:
1846:
1824:
1685:Oat beta-glucan
1672:Polysaccharides
1666:
1629:
1623:
1605:
1577:
1508:
1502:Neuraminic acid
1480:
1452:
1345:
1280:
1242:
1209:
1183:Monosaccharides
1177:
1146:
1115:
1109:
1079:
1078:
1038:
1032:
1028:
981:
977:
954:
950:
911:Front Microbiol
903:
899:
853:
849:
807:
803:
746:
742:
737:
697:
622:
555:-linked glycans
549:
545:
541:
522:
515:
510:
509:
508: ?)
499:
495:
491:
487:
453:
449:
445:
439:
425:
422:
421:O1(O)(OC(O)1O)C
417:
416:
405:
402:
401:
398:
392:
391:
388:
382:
381:
370:
350:
337:
325:
305:
285:
265:
252:
241:
228:
214:
210:
202:
201:
168:
128:
125:
116:
115:
114:
113:
112:
101:
100:
90:
87:
76:
74:
51:
48:
31:
29:
12:
11:
5:
1886:
1876:
1875:
1870:
1865:
1848:
1847:
1845:
1844:
1833:
1830:
1829:
1826:
1825:
1823:
1822:
1817:
1816:
1815:
1810:
1800:
1795:
1790:
1785:
1783:Levan beta 2β6
1780:
1775:
1774:
1773:
1757:
1746:
1745:
1744:
1728:
1719:
1714:
1713:
1712:
1707:
1702:
1697:
1692:
1687:
1676:
1674:
1668:
1667:
1665:
1664:
1659:
1653:
1647:
1641:
1635:
1633:
1625:
1624:
1622:
1621:
1615:
1613:
1607:
1606:
1604:
1603:
1598:
1593:
1587:
1585:
1583:Trisaccharides
1579:
1578:
1576:
1575:
1570:
1565:
1560:
1555:
1550:
1545:
1540:
1535:
1529:
1527:
1518:
1514:
1513:
1510:
1509:
1507:
1506:
1505:
1504:
1494:
1488:
1486:
1482:
1481:
1479:
1478:
1477:
1476:
1471:
1469:Mannoheptulose
1462:
1460:
1454:
1453:
1451:
1450:
1449:
1448:
1443:
1438:
1430:
1429:
1428:
1423:
1418:
1413:
1403:
1402:
1401:
1396:
1391:
1386:
1381:
1376:
1371:
1366:
1355:
1353:
1347:
1346:
1344:
1343:
1342:
1341:
1331:
1330:
1329:
1324:
1316:
1315:
1314:
1309:
1304:
1299:
1290:
1288:
1282:
1281:
1279:
1278:
1277:
1276:
1268:
1267:
1266:
1261:
1252:
1250:
1244:
1243:
1241:
1240:
1239:
1238:
1230:
1229:
1228:
1226:Glyceraldehyde
1219:
1217:
1211:
1210:
1208:
1207:
1206:
1205:
1203:Glycolaldehyde
1196:
1194:
1185:
1179:
1178:
1176:
1175:
1170:
1165:
1160:
1154:
1152:
1148:
1147:
1145:
1144:
1139:
1134:
1129:
1123:
1121:
1117:
1116:
1108:
1107:
1100:
1093:
1085:
1077:
1076:
1049:(3): 151β166.
1026:
975:
964:(6): 479β497.
948:
897:
876:(7): 679β687.
847:
826:(7): 41Rβ53R.
801:
739:
738:
736:
733:
732:
731:
723:
718:
713:
708:
696:
693:
677:Natural Killer
619:-configuration
577:polysaccharide
547:
543:
539:
520:
517:
516:
511:
489:
488:
484:standard state
481:
478:
477:
471:
470:
466:
465:
462:
456:
455:
451:
447:
443:
440:
435:
432:
431:
427:
426:
424:
423:
420:
412:
411:
410:
407:
406:
404:
403:
399:
396:
395:
393:
389:
386:
385:
377:
376:
375:
372:
371:
369:
368:
360:
358:
352:
351:
349:
348:
340:
338:
330:
327:
326:
324:
323:
315:
313:
307:
306:
304:
303:
295:
293:
287:
286:
284:
283:
275:
273:
267:
266:
264:
263:
255:
253:
246:
243:
242:
240:
239:
231:
229:
224:
221:
220:
216:
215:
208:
204:
203:
177:
176:
170:
169:
162:
156:
155:
151:
150:
142:
141:
72:
64:permanent link
27:
16:
15:
9:
6:
4:
3:
2:
1885:
1874:
1871:
1869:
1866:
1864:
1861:
1860:
1858:
1843:
1835:
1834:
1831:
1821:
1818:
1814:
1811:
1809:
1806:
1805:
1804:
1801:
1799:
1796:
1794:
1791:
1789:
1786:
1784:
1781:
1779:
1778:Hemicellulose
1776:
1772:
1769:
1768:
1767:
1766:
1762:
1758:
1756:
1755:
1751:
1747:
1743:
1740:
1739:
1738:
1737:
1733:
1729:
1727:
1723:
1720:
1718:
1715:
1711:
1708:
1706:
1703:
1701:
1698:
1696:
1693:
1691:
1688:
1686:
1683:
1682:
1681:
1678:
1677:
1675:
1673:
1669:
1663:
1660:
1657:
1654:
1651:
1648:
1645:
1642:
1640:
1637:
1636:
1634:
1632:
1626:
1620:
1617:
1616:
1614:
1612:
1608:
1602:
1599:
1597:
1594:
1592:
1589:
1588:
1586:
1584:
1580:
1574:
1571:
1569:
1566:
1564:
1561:
1559:
1556:
1554:
1551:
1549:
1546:
1544:
1541:
1539:
1536:
1534:
1531:
1530:
1528:
1526:
1525:Disaccharides
1522:
1519:
1515:
1503:
1500:
1499:
1498:
1495:
1493:
1490:
1489:
1487:
1483:
1475:
1474:Sedoheptulose
1472:
1470:
1467:
1466:
1465:Ketoheptoses
1464:
1463:
1461:
1459:
1455:
1447:
1444:
1442:
1439:
1437:
1434:
1433:
1432:Deoxy sugars
1431:
1427:
1424:
1422:
1419:
1417:
1414:
1412:
1409:
1408:
1407:
1404:
1400:
1397:
1395:
1392:
1390:
1387:
1385:
1382:
1380:
1377:
1375:
1372:
1370:
1367:
1365:
1362:
1361:
1360:
1357:
1356:
1354:
1352:
1348:
1340:
1337:
1336:
1335:
1332:
1328:
1325:
1323:
1320:
1319:
1318:Ketopentoses
1317:
1313:
1310:
1308:
1305:
1303:
1300:
1298:
1295:
1294:
1293:Aldopentoses
1292:
1291:
1289:
1287:
1283:
1275:
1272:
1271:
1269:
1265:
1262:
1260:
1257:
1256:
1255:Aldotetroses
1254:
1253:
1251:
1249:
1245:
1237:
1234:
1233:
1231:
1227:
1224:
1223:
1221:
1220:
1218:
1216:
1212:
1204:
1201:
1200:
1198:
1197:
1195:
1193:
1189:
1186:
1184:
1180:
1174:
1171:
1169:
1166:
1164:
1161:
1159:
1156:
1155:
1153:
1149:
1143:
1140:
1138:
1135:
1133:
1130:
1128:
1125:
1124:
1122:
1118:
1114:
1113:carbohydrates
1106:
1101:
1099:
1094:
1092:
1087:
1086:
1083:
1072:
1068:
1064:
1060:
1056:
1052:
1048:
1044:
1037:
1030:
1022:
1018:
1014:
1010:
1006:
1002:
998:
994:
990:
986:
979:
971:
967:
963:
959:
952:
944:
940:
935:
930:
925:
920:
916:
912:
908:
901:
893:
889:
884:
879:
875:
871:
867:
864:(July 1999).
863:
857:
851:
843:
839:
834:
829:
825:
821:
817:
811:
805:
797:
793:
789:
785:
781:
777:
772:
767:
763:
759:
755:
751:
744:
740:
730:
729:
724:
722:
719:
717:
714:
712:
709:
702:
699:
698:
692:
690:
686:
683:. Therefore,
682:
678:
674:
670:
666:
660:
658:
654:
649:
647:
643:
641:
635:
630:
628:
620:
616:
611:
607:
602:
600:
596:
592:
589:
585:
584:Ξ±(1β3) linked
581:
578:
575:
571:
570:cell surface.
568:
564:
560:
556:
554:
537:
533:
530:
526:
514:
507:
502:
485:
479:
476:
472:
467:
463:
461:
458:
457:
441:
438:
434:
433:
428:
419:
418:
415:
408:
394:
384:
383:
380:
373:
366:
362:
361:
359:
357:
354:
353:
346:
342:
341:
339:
333:
329:
328:
321:
317:
316:
314:
312:
309:
308:
301:
297:
296:
294:
292:
289:
288:
281:
277:
276:
274:
272:
269:
268:
261:
257:
256:
254:
250:
245:
244:
237:
233:
232:
230:
227:
223:
222:
217:
205:
199:
193:
189:
185:
181:
175:
171:
161:
157:
152:
148:
143:
139:
134:
123:
110:
106:
93:
84:
80:
75:
68:
67:
65:
54:
39:
35:
30:
23:
1868:Deoxy sugars
1759:
1748:
1730:
1662:Maltodextrin
1543:Isomaltulose
1435:
1334:Deoxy sugars
1270:Ketotetrose
1173:Mutarotation
1046:
1042:
1029:
988:
984:
978:
961:
957:
951:
914:
910:
900:
873:
870:Glycobiology
869:
850:
823:
820:Glycobiology
819:
804:
753:
749:
743:
727:
669:Fucosylation
667:
661:
653:Ξ±-fucosidase
650:
639:
633:
631:
603:
588:carbohydrate
552:
524:
523:
300:ChEMBL469449
219:Identifiers
207:Other names
197:
191:
187:
183:
179:
20:This is the
19:
18:
1863:Aldohexoses
1820:Xanthan gum
1808:Amylopectin
1680:Beta-glucan
1591:Maltotriose
1406:Ketohexoses
1359:Aldohexoses
1339:Deoxyribose
1274:Erythrulose
1232:Ketotriose
1222:Aldotriose
673:Fc receptor
610:deoxy sugar
532:deoxy sugar
430:Properties
1857:Categories
1596:Melezitose
1538:Isomaltose
1533:Cellobiose
1199:Aldodiose
771:10197/8191
735:References
716:Fucosidase
701:Digitalose
612:) and the
597:-mediated
460:Molar mass
365:28RYY2IV3F
311:ChemSpider
280:CHEBI:2181
247:3D model (
226:CAS Number
213:-galactose
160:IUPAC name
1873:Pyranoses
1750:Galactose
1705:Cellulose
1695:Sizofiran
1619:Stachyose
1601:Raffinose
1568:Trehalose
1553:Lactulose
1374:Galactose
1297:Arabinose
1259:Erythrose
1111:Types of
1021:206548002
1005:0036-8075
780:0963-9969
657:lysosomes
655:found in
646:H antigen
627:galactose
559:mammalian
534:with the
236:2438-80-4
1842:Category
1771:Glycogen
1754:Galactan
1732:Fructose
1717:Chitosan
1690:Lentinan
1639:Acarbose
1573:Turanose
1517:Multiple
1458:Heptoses
1446:Rhamnose
1441:Fuculose
1426:Tagatose
1411:Fructose
1327:Xylulose
1322:Ribulose
1286:Pentoses
1248:Tetroses
1151:Geometry
1142:Pyranose
1137:Furanose
1063:28466278
1043:BioDrugs
1013:24385630
943:25914689
892:10362837
842:12651883
796:10531419
788:28865611
695:See also
606:hydroxyl
580:fucoidan
209:6-Deoxy-
163:6-Deoxy-
131:-Fucose
122:Fructose
83:contribs
73:Teaktl17
38:contribs
28:Teaktl17
1813:Amylose
1761:Glucose
1736:Fructan
1726:Dextran
1722:Dextrin
1700:Zymosan
1563:Sucrose
1558:Maltose
1548:Lactose
1497:Nonoses
1492:Octoses
1485:Above 7
1421:Sorbose
1416:Psicose
1394:Mannose
1379:Glucose
1369:Altrose
1351:Hexoses
1264:Threose
1215:Trioses
1120:General
1071:3722081
985:Science
934:4392319
917:: 288.
711:Fucitol
707:-fucose
599:allergy
591:antigen
574:seaweed
557:on the
506:what is
504: (
454:
332:PubChem
1803:Starch
1798:Pectin
1793:Mannan
1788:Lignin
1765:Glucan
1742:Inulin
1710:Chitin
1436:Fucose
1399:Talose
1384:Gulose
1364:Allose
1312:Xylose
1307:Ribose
1302:Lyxose
1192:Dioses
1168:Epimer
1158:Anomer
1132:Ketose
1127:Aldose
1069:
1061:
1019:
1011:
1003:
941:
931:
890:
840:
794:
786:
778:
582:. The
563:insect
529:hexose
525:Fucose
501:verify
498:
414:SMILES
291:ChEMBL
154:Names
1658:(IMO)
1652:(GOS)
1646:(FOS)
1628:Other
1389:Idose
1067:S2CID
1039:(PDF)
1017:S2CID
792:S2CID
567:plant
527:is a
379:InChI
345:17106
320:16190
271:ChEBI
249:JSmol
92:ββtop
53:ββtop
1059:PMID
1009:PMID
1001:ISSN
939:PMID
888:PMID
838:PMID
784:PMID
776:ISSN
689:FUT8
593:for
565:and
356:UNII
105:diff
79:talk
34:talk
1051:doi
993:doi
989:343
966:doi
929:PMC
919:doi
878:doi
828:doi
766:hdl
758:doi
675:of
595:IgE
335:CID
96:fmt
57:fmt
43:at
1859::
1763:/
1752:/
1734:/
1724:/
1065:.
1057:.
1047:31
1045:.
1041:.
1015:.
1007:.
999:.
987:.
962:74
960:.
937:.
927:.
913:.
909:.
886:.
872:.
868:.
836:.
824:13
822:.
818:.
790:.
782:.
774:.
764:.
754:99
752:.
659:.
638:Ξ²-
629:.
601:.
561:,
544:12
448:12
190:,5
186:,4
182:,3
178:(2
107:)
94::
81:|
55::
36:|
1104:e
1097:t
1090:v
1073:.
1053::
1023:.
995::
972:.
968::
945:.
921::
915:6
894:.
880::
874:9
844:.
830::
798:.
768::
760::
705:D
663:L
640:N
634:N
625:-
623:L
615:L
553:N
548:5
546:O
542:H
540:6
538:C
496:Y
452:5
450:O
446:H
444:6
442:C
251:)
211:L
198:H
196:2
192:S
188:R
184:R
180:S
165:L
129:L
124:.
103:(
98:)
88:(
85:)
77:(
59:)
49:(
40:)
32:(
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